hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080501/iprscan-20080501-16473439/chunk_1/iprscan-20080501-16473439.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA1079 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF07714.7.fs Protein tyrosine kinase 165.1 8.5e-48 1 PF07714.7.ls Protein tyrosine kinase 166.9 4.7e-47 1 PF00069.15.ls Protein kinase domain 34.6 1.2e-10 1 PF00069.15.fs Protein kinase domain 35.9 4.5e-10 2 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00069.15.fs 1/2 159 308 .. 1 159 [. 33.9 1.7e-09 PF07714.7.fs 1/1 159 429 .. 1 272 [] 165.1 8.5e-48 PF00069.15.ls 1/1 159 429 .. 1 287 [] 34.6 1.2e-10 PF07714.7.ls 1/1 159 429 .. 1 272 [] 166.9 4.7e-47 Alignments of top-scoring domains: PF00069.15.fs: domain 1 of 2, from 159 to 308: score 33.9, E = 1.7e-09 *->yelleklGsGsfGtVykakhkgtgk...iVAvKiikkrkekskkdkt + ++ +G G fG+V ++ ++ tg + +V vK++k + + +++d KIAA1079 159 LNYIQEIGNGWFGKVLLG-EIYTGTsvaRVIVKELKASANPKEQDTF 204 arrlsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrvldLfdy + + E ++ L+HpNI+++ + + + + lV+E+c+ G dL++y KIAA1079 205 LKNG-EPYYI--LQHPNILQCVGQCVEAIPYLLVFEFCDLG----DLKAY 247 ls.e.trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILl l++e+ +++g + ++++a +++ gl+ +H+ ++H DL + N++l KIAA1079 248 LRsEqEHMRGDS--QTMLLQRMACEVAAGLAAMHKLHFLHSDLALRNCFL 295 dnngvvdaflKiaDFGl<-* ++ +v K++D G+ KIAA1079 296 TSDLNV----KVGDYGI 308 PF07714.7.fs: domain 1 of 1, from 159 to 429: score 165.1, E = 8.5e-48 *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtLkeigaseeeie l ++++G G FG+V +G+ + + V VK Lk +a ++e KIAA1079 159 LNYIQEIGNGWFGKVLLGEIY--TGTSVARVIVKELKA-SANPKE-- 200 redFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGdL ++ Fl+ + l +HpNi+++ G c++ P +++V+E++ +GdL KIAA1079 201 QDTFLKNGEPYYIL-QHPNILQCVGQCVE-AIP----YLLVFEFCDLGDL 244 ldfLrkhregrpL....tlkdLlsfalQiAkGMeYLesknfvHRDLAARN + +Lr+ +++ ++++ + L +a ++A+G++ + +f H DLA RN KIAA1079 245 KAYLRSE--QEHMrgdsQTMLLQRMACEVAAGLAAMHKLHFLHSDLALRN 292 cLVsenlvVKIsDFGL..aRdiynddyYvrkkgggk.lPvkWmAPEslky c ++++l VK++D G + +R+ + Y +++ k +P +W+APE KIAA1079 293 CFLTSDLNVKVGDYGIgfSRYK---EDY-IETDDKKvFPLRWTAPELVTS 338 gk.......FtskSDVWSFGVlLWEiftlGeqPFYpgmsneevlellyed ++ + + t S +WS GV+LWE+f +qP Y ++sn +vl+++ + KIAA1079 339 FQdrlltadQTKYSNIWSLGVTLWELFDNAAQP-YSNLSNLDVLNQV-IR 386 .......GyRLprPenCPdelYdlMlqCWaedPedRPtFselveeL<-* +++++ + +L++P +d Y++++ CW Pe+RP +++++ L KIAA1079 387 erdtklpKPQLEQPY--SDRWYEVLQFCW-LSPEKRPAAEDVHRLL 429 PF00069.15.ls: domain 1 of 1, from 159 to 429: score 34.6, E = 1.2e-10 *->yelleklGsGsfGtVykakhkgtgk...iVAvKiikkrkekskkdkt + ++ +G G fG+V ++ ++ tg + +V vK++k + + +++d KIAA1079 159 LNYIQEIGNGWFGKVLLG-EIYTGTsvaRVIVKELKASANPKEQDTF 204 arrlsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrvldLfdy + + E ++ L+HpNI+++ + + + + lV+E+c+ G dL++y KIAA1079 205 LKNG-EPYYI--LQHPNILQCVGQCVEAIPYLLVFEFCDLG----DLKAY 247 ls.e.trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILl l++e+ +++g + ++++a +++ gl+ +H+ ++H DL + N++l KIAA1079 248 LRsEqEHMRGDS--QTMLLQRMACEVAAGLAAMHKLHFLHSDLALRNCFL 295 dnngvvdaflKiaDFGlAkkls.....t.sss.lttfvGTpwYmAPEv.. ++ +v K++D G+ +s+ ++++ + ++f +++ APE+ + KIAA1079 296 TSDLNV----KVGDYGIG--FSrykedYiETDdKKVFP--LRWTAPELvt 337 .....llggngygtkvDvWSlGvilyelltGk.pPFsgevqdsldqlqli + +++ll + ++ + +WSlGv+l+el+ P+s+ + ++l KIAA1079 338 sfqdrLL-TADQTKYSNIWSLGVTLWELFDNAaQPYSNL----SNLDVLN 382 rkilgpplefdspewdsisrsefrrlpnlseeakdLikkcLnkDPskRlt + i++++++ + p+ ++ s+ +++ c+ + P+kR+ KIAA1079 383 QVIRERDTKLPKPQLEQPY----------SDRWYEVLQFCW-LSPEKRPA 421 aeeilqHPwf<-* ae++ + KIAA1079 422 AEDVHRL--L 429 PF07714.7.ls: domain 1 of 1, from 159 to 429: score 166.9, E = 4.7e-47 *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtLkeigaseeeie l ++++G G FG+V +G+ + + V VK Lk +a ++e KIAA1079 159 LNYIQEIGNGWFGKVLLGEIY--TGTSVARVIVKELKA-SANPKE-- 200 redFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGdL ++ Fl+ + l +HpNi+++ G c++ P +++V+E++ +GdL KIAA1079 201 QDTFLKNGEPYYIL-QHPNILQCVGQCVE-AIP----YLLVFEFCDLGDL 244 ldfLrkhregrpL....tlkdLlsfalQiAkGMeYLesknfvHRDLAARN + +Lr+ +++ ++++ + L +a ++A+G++ + +f H DLA RN KIAA1079 245 KAYLRSE--QEHMrgdsQTMLLQRMACEVAAGLAAMHKLHFLHSDLALRN 292 cLVsenlvVKIsDFGL..aRdiynddyYvrkkgggk.lPvkWmAPEslky c ++++l VK++D G + +R+ + Y +++ k +P +W+APE KIAA1079 293 CFLTSDLNVKVGDYGIgfSRYK---EDY-IETDDKKvFPLRWTAPELVTS 338 gk.......FtskSDVWSFGVlLWEiftlGeqPFYpgmsneevlellyed ++ + + t S +WS GV+LWE+f +qP Y ++sn +vl+++ + KIAA1079 339 FQdrlltadQTKYSNIWSLGVTLWELFDNAAQP-YSNLSNLDVLNQV-IR 386 .......GyRLprPenCPdelYdlMlqCWaedPedRPtFselveeL<-* +++++ + +L++P +d Y++++ CW Pe+RP +++++ L KIAA1079 387 erdtklpKPQLEQPY--SDRWYEVLQFCW-LSPEKRPAAEDVHRLL 429 //