hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-17573515/chunk_1/iprscan-20080502-17573515.nocrc
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Query sequence: KIAA0959
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
PF00617.10.ls RasGEF domain                                  287.1      3e-83   1
PF00617.10.fs RasGEF domain                                  285.2    1.1e-82   1
PF00618.10.fs Guanine nucleotide exchange factor for Ras-l   113.8    1.4e-32   1
PF00618.10.ls Guanine nucleotide exchange factor for Ras-l   115.7    1.2e-31   1
PF00788.13.ls Ras association (RalGDS/AF-6) domain            72.1    1.6e-18   1
PF00788.13.fs Ras association (RalGDS/AF-6) domain            70.3    5.7e-18   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PF00618.10.ls   1/1     120   226 ..     1   109 []   115.7  1.2e-31
PF00618.10.fs   1/1     120   226 ..     1   109 []   113.8  1.4e-32
PF00617.10.fs   1/1     281   502 ..     1   227 []   285.2  1.1e-82
PF00617.10.ls   1/1     281   502 ..     1   227 []   287.1    3e-83
PF00788.13.fs   1/1     700   787 ..     1    97 []    70.3  5.7e-18
PF00788.13.ls   1/1     700   787 ..     1    97 []    72.1  1.6e-18

Alignments of top-scoring domains:
PF00618.10.ls: domain 1 of 1, from 120 to 226: score 115.7, E = 1.2e-31
                   *->qvkagtlekLvehLtshskl.DssFvstFLlTYRsFttpaeLlekLi
                      ++kagtlekLve L+  ++ +D +++s+FL TYR F+++ e+le+L+
    KIAA0959   120    TIKAGTLEKLVENLLTAFGDnDFTYISIFLSTYRGFASTKEVLELLL 166  

                   eRywseippp.nl.qssknsweekkkllkpiqlrvlnvlrhWvenyfeDF
                   +Ry   ++ ++n + + ++s +e+k   + i++ + ++lr W++++ eDF
    KIAA0959   167 DRY--GNLTSpNCeEDGSQSSSESK---MVIRNAIASILRAWLDQCAEDF 211  

                   adeddpellsrLleF<-*
                   ++++ + +l++Ll++   
    KIAA0959   212 REPPHFPCLQKLLDY    226  

PF00618.10.fs: domain 1 of 1, from 120 to 226: score 113.8, E = 1.4e-32
                   *->qvkagtlekLvehLtshskl.DssFvstFLlTYRsFttpaeLlekLi
                      ++kagtlekLve L+  ++ +D +++s+FL TYR F+++ e+le+L+
    KIAA0959   120    TIKAGTLEKLVENLLTAFGDnDFTYISIFLSTYRGFASTKEVLELLL 166  

                   eRywseippp.nl.qssknsweekkkllkpiqlrvlnvlrhWvenyfeDF
                   +Ry   ++ ++n + + ++s +e+k   + i++ + ++lr W++++ eDF
    KIAA0959   167 DRY--GNLTSpNCeEDGSQSSSESK---MVIRNAIASILRAWLDQCAEDF 211  

                   adeddpellsrLleF<-*
                   ++++ + +l++Ll++   
    KIAA0959   212 REPPHFPCLQKLLDY    226  

PF00617.10.fs: domain 1 of 1, from 281 to 502: score 285.2, E = 1.1e-82
                   *->LlldplelAkQLTLlEhelfkkItpfefLgsKmKHEGPqvWgkksfk
                        ++ +++A+QLT ++++lfkk++p ++Lg         +W+++++k
    KIAA0959   281    TCFSEDLVAEQLTYMDAQLFKKVVPHHCLG--------CIWSRRDKK 319  

                   vkneripnidktiknfNqltnfvsetIlkqeFPTNPEFSKkvdpkkRaev
                   ++ +++p+i++ti++fN+lt +v +tIl+ +          ++   Ra++
    KIAA0959   320 ENKHLAPTIRATISQFNTLTKCVVSTILGGK---------ELKTQQRAKI 360  

                   iqkfIqVAdhcReLnNFnSllaIisALysspIyRLkkTWekvppqslklI
                   i+k+I++A +cR L+NF+Sl aI+sAL+s++IyRLkkTW++vp++     
    KIAA0959   361 IEKWINIAHECRLLKNFSSLRAIVSALQSNSIYRLKKTWAAVPRDRMLM- 409  

                   feeLnkLmdsdrNfsnyRelLksigplappnLd.................
                   feeL+ ++++++N+ ++RelL ++g+++++nLd++ ++++++++++ + +
    KIAA0959   410 FEELSDIFSDHNNHLTSRELLMKEGTSKFANLDssvkenqkrtqrrlqlq 459  

                   .ddfvraPCVPFfGvYLsDLtfleeGnpdyleekKINtnlvNFsKrrk<-
                   +d +v +++VP++G++L+DLt+l+++  dy e     ++l+NF+Krr+  
    KIAA0959   460 kDMGVMQGTVPYLGTFLTDLTMLDTALQDYIE-----GGLINFEKRRR   502  

                   *
                    
    KIAA0959     -   -    

PF00617.10.ls: domain 1 of 1, from 281 to 502: score 287.1, E = 3e-83
                   *->LlldplelAkQLTLlEhelfkkItpfefLgsKmKHEGPqvWgkksfk
                        ++ +++A+QLT ++++lfkk++p ++Lg         +W+++++k
    KIAA0959   281    TCFSEDLVAEQLTYMDAQLFKKVVPHHCLG--------CIWSRRDKK 319  

                   vkneripnidktiknfNqltnfvsetIlkqeFPTNPEFSKkvdpkkRaev
                   ++ +++p+i++ti++fN+lt +v +tIl+ +          ++   Ra++
    KIAA0959   320 ENKHLAPTIRATISQFNTLTKCVVSTILGGK---------ELKTQQRAKI 360  

                   iqkfIqVAdhcReLnNFnSllaIisALysspIyRLkkTWekvppqslklI
                   i+k+I++A +cR L+NF+Sl aI+sAL+s++IyRLkkTW++vp++     
    KIAA0959   361 IEKWINIAHECRLLKNFSSLRAIVSALQSNSIYRLKKTWAAVPRDRMLM- 409  

                   feeLnkLmdsdrNfsnyRelLksigplappnLd.................
                   feeL+ ++++++N+ ++RelL ++g+++++nLd++ ++++++++++ + +
    KIAA0959   410 FEELSDIFSDHNNHLTSRELLMKEGTSKFANLDssvkenqkrtqrrlqlq 459  

                   .ddfvraPCVPFfGvYLsDLtfleeGnpdyleekKINtnlvNFsKrrk<-
                   +d +v +++VP++G++L+DLt+l+++  dy e     ++l+NF+Krr+  
    KIAA0959   460 kDMGVMQGTVPYLGTFLTDLTMLDTALQDYIE-----GGLINFEKRRR   502  

                   *
                    
    KIAA0959     -   -    

PF00788.13.fs: domain 1 of 1, from 700 to 787: score 70.3, E = 5.7e-18
                   *->dsgvlrVygedgtpgtyktilvskntTaeeViralLrKfgldaddpe
                      d++++r+  ed++ ++yk+i++++++ ++ Vi+ ++ K++ld d  e
    KIAA0959   700    DTCIIRISVEDNNGNMYKSIMLTSQDKTPAVIQRAMLKHNLDSDPAE 746  

                   dyvLvEvslvlerggeerrvLpddEkPlqiqlqlkrdaqrsrFlLrrred
                   +y+Lv    +++++++e  v+pd++++++++        +  F+Lr+++ 
    KIAA0959   747 EYELV----QVISEDKEL-VIPDSANVFYAMNSQV----NFDFILRKKNS 787  

                   <-*
                      
    KIAA0959     -     -    

PF00788.13.ls: domain 1 of 1, from 700 to 787: score 72.1, E = 1.6e-18
                   *->dsgvlrVygedgtpgtyktilvskntTaeeViralLrKfgldaddpe
                      d++++r+  ed++ ++yk+i++++++ ++ Vi+ ++ K++ld d  e
    KIAA0959   700    DTCIIRISVEDNNGNMYKSIMLTSQDKTPAVIQRAMLKHNLDSDPAE 746  

                   dyvLvEvslvlerggeerrvLpddEkPlqiqlqlkrdaqrsrFlLrrred
                   +y+Lv    +++++++e  v+pd++++++++        +  F+Lr+++ 
    KIAA0959   747 EYELV----QVISEDKEL-VIPDSANVFYAMNSQV----NFDFILRKKNS 787  

                   <-*
                      
    KIAA0959     -     -    

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