hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-15435171/chunk_1/iprscan-20080502-15435171.nocrc
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Query sequence: KIAA0881
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
PF00069.15.ls Protein kinase domain                       262.8    6.6e-76   1
PF00069.15.fs Protein kinase domain                       260.9    2.4e-75   1
PF07714.7.fs Protein tyrosine kinase                     103.0    8.7e-30   2
PF07714.7.ls Protein tyrosine kinase                      94.4    3.2e-25   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
PF00069.15.fs   1/1      43   296 ..     1   287 []   260.9  2.4e-75
PF07714.7.fs   1/2      43   186 ..     1   158 [.    89.6  6.7e-26
PF07714.7.ls   1/1      43   296 ..     1   272 []    94.4  3.2e-25
PF00069.15.ls   1/1      43   296 ..     1   287 []   262.8  6.6e-76
PF07714.7.fs   2/2     203   233 ..   182   209 ..    13.4  0.00083

Alignments of top-scoring domains:
PF00069.15.fs: domain 1 of 1, from 43 to 296: score 260.9, E = 2.4e-75
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkr.kekskkdktar
                      +  l+ +G GsfG Vy a+++ ++++VA+K++++++k++ +k++  +
    KIAA0881    43    FSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSgKQSNEKWQDII 89   

                   rlsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGL.rvldLfdyl
                   +  E++ l++L+HpN +++++++ ++   +lV+Eyc g  +++l+ +   
    KIAA0881    90 K--EVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSAsDLLEVH--- 134  

                   setrrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldnn
                        k+pl  +e e+  +    l+gl+YLHs++ iHRD+K  NILl++ 
    KIAA0881   135 -----KKPL--QEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEP 177  

                   gvvdaflKiaDFGlAkklstsss.lttfvGTpwYmAPEvll..ggngygt
                   g v    K++DFG+A  +     ++++fvGTp++mAPEv+l  +   y+ 
    KIAA0881   178 GLV----KLGDFGSASIM----ApANSFVGTPYWMAPEVILamDEGQYDG 219  

                   kvDvWSlGvilyelltGkpPFsgevqds.ldqlqlirkilgpplefdspe
                   kvDvWSlG++++el+ +kpP  +    +  + l+ i+++ +p l +  + 
    KIAA0881   220 KVDVWSLGITCIELAERKPPLFNM---NaMSALYHIAQNESPVLQSGHW- 265  

                   wdsisrsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<-*
                                  se ++ ++++cL+k P++R+t e +l+H ++   
    KIAA0881   266 ---------------SEYFRNFVDSCLQKIPQDRPTSEVLLKHRFV    296  

PF07714.7.fs: domain 1 of 2, from 43 to 186: score 89.6, E = 6.7e-26
                   *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtLkeigaseeei.
                      ++ ++++G+G+FG Vy ++       +   VA+K++   ++s ++ +
    KIAA0881    43    FSDLREIGHGSFGAVYFARDV----RNSEVVAIKKM---SYSGKQSn 82   

                   e.redFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegG
                   e+++d ++E++ + kl +HpN +++ G+ ++ +       ++V+Ey+ +G
    KIAA0881    83 EkWQDIIKEVRFLQKL-RHPNTIQYRGCYLR-EHT----AWLVMEYC-LG 125  

                   dLldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcL
                   +  d L  h  ++pL   ++    +   +G++YL+s+n++HRD+ A N+L
    KIAA0881   126 SASDLLEVH--KKPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNIL 173  

                   VsenlvVKIsDFG<-*
                   +se++ VK +DFG   
    KIAA0881   174 LSEPGLVKLGDFG    186  

PF07714.7.ls: domain 1 of 1, from 43 to 296: score 94.4, E = 3.2e-25
                   *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtLkeigaseeei.
                      ++ ++++G+G+FG Vy ++       +   VA+K++   ++s ++ +
    KIAA0881    43    FSDLREIGHGSFGAVYFARDV----RNSEVVAIKKM---SYSGKQSn 82   

                   e.redFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegG
                   e+++d ++E++ + kl +HpN +++ G+ ++ +       ++V+Ey+ +G
    KIAA0881    83 EkWQDIIKEVRFLQKL-RHPNTIQYRGCYLR-EHT----AWLVMEYC-LG 125  

                   dLldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcL
                   +  d L  h  ++pL   ++    +   +G++YL+s+n++HRD+ A N+L
    KIAA0881   126 SASDLLEVH--KKPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNIL 173  

                   VsenlvVKIsDFGLaRdiynddyYvrkkgggk.lPvkWmAPEslkygk..
                   +se++ VK +DFG a  +        +  ++      WmAPE++  + ++
    KIAA0881   174 LSEPGLVKLGDFGSASIM--------APANSFvGTPYWMAPEVILAMDeg 215  

                   .FtskSDVWSFGVlLWEiftlGeqPFYpgmsneevlellyedGyRLprPe
                   ++  k DVWS G+++ E+    ++P   +m     l +++++     +  
    KIAA0881   216 qYDGKVDVWSLGITCIELAE-RKPP-LFNMNAMSALYHIAQNESPVLQSG 263  

                   nCPdelYdlMlqCWaedPedRPtFsel..veeL<-*
                   + ++   +   +C ++ P+dRPt + l ++++    
    KIAA0881   264 HWSEYFRNFVDSCLQKIPQDRPTSEVLlkHRFV    296  

PF00069.15.ls: domain 1 of 1, from 43 to 296: score 262.8, E = 6.6e-76
                   *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkr.kekskkdktar
                      +  l+ +G GsfG Vy a+++ ++++VA+K++++++k++ +k++  +
    KIAA0881    43    FSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSgKQSNEKWQDII 89   

                   rlsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGL.rvldLfdyl
                   +  E++ l++L+HpN +++++++ ++   +lV+Eyc g  +++l+ +   
    KIAA0881    90 K--EVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSAsDLLEVH--- 134  

                   setrrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldnn
                        k+pl  +e e+  +    l+gl+YLHs++ iHRD+K  NILl++ 
    KIAA0881   135 -----KKPL--QEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEP 177  

                   gvvdaflKiaDFGlAkklstsss.lttfvGTpwYmAPEvll..ggngygt
                   g v    K++DFG+A  +     ++++fvGTp++mAPEv+l  +   y+ 
    KIAA0881   178 GLV----KLGDFGSASIM----ApANSFVGTPYWMAPEVILamDEGQYDG 219  

                   kvDvWSlGvilyelltGkpPFsgevqds.ldqlqlirkilgpplefdspe
                   kvDvWSlG++++el+ +kpP  +    +  + l+ i+++ +p l +  + 
    KIAA0881   220 KVDVWSLGITCIELAERKPPLFNM---NaMSALYHIAQNESPVLQSGHW- 265  

                   wdsisrsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<-*
                                  se ++ ++++cL+k P++R+t e +l+H ++   
    KIAA0881   266 ---------------SEYFRNFVDSCLQKIPQDRPTSEVLLKHRFV    296  

PF07714.7.fs: domain 2 of 2, from 203 to 233: score 13.4, E = 0.00083
                   *->WmAPEslkygk...FtskSDVWSFGVlLWEi<-*
                      WmAPE++  + ++++  k DVWS G+++ E+   
    KIAA0881   203    WMAPEVILAMDegqYDGKVDVWSLGITCIEL    233  

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