hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-13532198/chunk_1/iprscan-20080502-13532198.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA0816 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF00058.8.ls Low-density lipoprotein receptor repeat 748.0 5.5e-222 19 PF00058.8.fs Low-density lipoprotein receptor repeat 736.8 3.7e-221 20 PF00057.9.fs Low-density lipoprotein receptor domain 427.5 1.6e-137 8 PF00057.9.ls Low-density lipoprotein receptor domain 442.8 4.1e-130 8 PF00008.17.fs EGF-like domain 147.5 3.2e-41 11 PF00008.17.ls EGF-like domain 147.2 4.2e-41 8 PF07645.6.fs Calcium binding EGF domain 54.4 9e-16 6 PF07645.6.ls Calcium binding EGF domain 32.7 1.2e-06 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00057.9.ls 1/8 73 114 .. 1 40 [] 42.4 1.4e-09 PF00057.9.fs 1/8 73 114 .. 1 40 [] 40.5 2.1e-12 PF00057.9.ls 2/8 117 153 .. 1 40 [] 66.8 6.5e-17 PF00057.9.fs 2/8 117 153 .. 1 40 [] 64.9 2.7e-20 PF00057.9.fs 3/8 156 191 .. 1 40 [] 50.5 1.2e-15 PF00057.9.ls 3/8 156 191 .. 1 40 [] 52.4 1.4e-12 PF00057.9.ls 4/8 194 230 .. 1 40 [] 64.4 3.4e-16 PF00057.9.fs 4/8 194 230 .. 1 40 [] 62.5 1.6e-19 PF00057.9.fs 5/8 237 273 .. 1 40 [] 48.2 6.8e-15 PF00057.9.ls 5/8 237 273 .. 1 40 [] 50.1 7e-12 PF00057.9.ls 6/8 277 313 .. 1 40 [] 54.5 3.3e-13 PF00057.9.fs 6/8 277 313 .. 1 40 [] 52.6 2.5e-16 PF00057.9.fs 7/8 316 352 .. 1 40 [] 59.2 1.9e-18 PF00057.9.ls 7/8 316 352 .. 1 40 [] 61.1 3.4e-15 PF00057.9.fs 8/8 358 397 .. 1 40 [] 49.2 3.1e-15 PF00057.9.ls 8/8 358 397 .. 1 40 [] 51.2 3.2e-12 PF00008.17.fs 6/11 406 441 .. 1 38 [] 29.7 2.1e-07 PF00008.17.ls 3/8 406 441 .. 1 38 [] 31.6 2.5e-06 PF07645.6.ls 1/1 443 481 .. 1 55 [] 32.7 1.2e-06 PF07645.6.fs 3/6 443 481 .. 1 55 [] 31.0 1.2e-08 PF00058.8.ls 1/19 528 569 .. 1 47 [] 41.5 2.6e-09 PF00058.8.fs 1/20 528 569 .. 1 47 [] 39.6 3.8e-11 PF00058.8.ls 2/19 571 612 .. 1 47 [] 56.7 7.2e-14 PF00058.8.fs 2/20 571 612 .. 1 47 [] 54.8 1e-15 PF00058.8.fs 3/20 614 656 .. 1 47 [] 48.0 1.1e-13 PF00058.8.ls 3/19 614 656 .. 1 47 [] 49.9 7.8e-12 PF00058.8.ls 4/19 658 699 .. 1 47 [] 52.8 1e-12 PF00058.8.fs 4/20 658 698 .. 1 46 [. 47.1 2.1e-13 PF00058.8.ls 5/19 701 741 .. 1 47 [] 13.4 0.041 PF00008.17.ls 5/8 750 784 .. 1 38 [] 20.5 0.0055 PF00058.8.fs 6/20 833 874 .. 1 47 [] 44.3 1.5e-12 PF00058.8.ls 6/19 833 874 .. 1 47 [] 46.2 1.1e-10 PF00058.8.fs 7/20 876 917 .. 1 47 [] 42.9 3.9e-12 PF00058.8.ls 7/19 876 917 .. 1 47 [] 44.8 2.8e-10 PF00058.8.fs 8/20 919 961 .. 1 47 [] 50.1 2.6e-14 PF00058.8.ls 8/19 919 961 .. 1 47 [] 52.0 1.8e-12 PF00058.8.ls 9/19 963 1004 .. 1 47 [] 41.4 2.9e-09 PF00058.8.fs 9/20 963 1002 .. 1 45 [. 37.1 2.2e-10 PF00058.8.fs 10/20 1004 1045 .. 1 47 [] 29.2 5e-08 PF00058.8.ls 10/19 1005 1045 .. 1 47 [] 26.2 0.00011 PF00008.17.ls 6/8 1054 1091 .. 1 38 [] 35.2 2.1e-07 PF00008.17.fs 9/11 1054 1091 .. 1 38 [] 33.2 2.1e-08 PF00058.8.fs 11/20 1141 1182 .. 1 47 [] 41.9 7.9e-12 PF00058.8.ls 11/19 1141 1182 .. 1 47 [] 43.8 5.5e-10 PF00058.8.ls 12/19 1184 1225 .. 1 47 [] 48.4 2.3e-11 PF00058.8.fs 12/20 1184 1225 .. 1 47 [] 46.5 3.3e-13 PF00058.8.ls 13/19 1227 1269 .. 1 47 [] 58.3 2.3e-14 PF00058.8.fs 13/20 1227 1269 .. 1 47 [] 56.4 3.3e-16 PF00058.8.fs 14/20 1271 1308 .. 1 44 [. 18.9 6.7e-05 PF00058.8.ls 14/19 1271 1311 .. 1 47 [] 19.1 0.007 PF00058.8.ls 15/19 1312 1353 .. 1 47 [] 8.0 0.22 PF00008.17.fs 10/11 1361 1396 .. 1 38 [] 34.4 9.9e-09 PF00008.17.ls 7/8 1361 1396 .. 1 38 [] 36.3 9.7e-08 PF00058.8.fs 16/20 1445 1486 .. 1 47 [] 32.9 3.9e-09 PF00058.8.ls 16/19 1445 1486 .. 1 47 [] 34.8 2.7e-07 PF00058.8.ls 17/19 1488 1526 .. 1 47 [] 23.9 0.00052 PF00058.8.fs 17/20 1488 1526 .. 1 47 [] 22.1 7.1e-06 PF00058.8.ls 18/19 1528 1570 .. 1 47 [] 58.0 2.8e-14 PF00058.8.fs 18/20 1528 1570 .. 1 47 [] 56.1 4.1e-16 PF00058.8.ls 19/19 1572 1617 .. 1 47 [] 28.8 1.8e-05 PF00058.8.fs 19/20 1572 1608 .. 1 43 [. 27.7 1.4e-07 Alignments of top-scoring domains: PF00057.9.ls: domain 1 of 8, from 73 to 114: score 42.4, E = 1.4e-09 *->stCgpdeFqCgsgr....rCIprswvCDGdpDCeDgSDEslenC<-* Cg+ +F+C+ + ++ CIp +w+CDGd+DC+D+SDE ++C KIAA0816 73 CACGRSHFTCAVSAlgecTCIPAQWQCDGDNDCGDHSDE--DGC 114 PF00057.9.fs: domain 1 of 8, from 73 to 114: score 40.5, E = 2.1e-12 *->stCgpdeFqCgsgr....rCIprswvCDGdpDCeDgSDEslenC<-* Cg+ +F+C+ + ++ CIp +w+CDGd+DC+D+SDE ++C KIAA0816 73 CACGRSHFTCAVSAlgecTCIPAQWQCDGDNDCGDHSDE--DGC 114 PF00057.9.ls: domain 2 of 8, from 117 to 153: score 66.8, E = 6.5e-17 *->stCgpdeFqCgsgrrCIprswvCDGdpDCeDgSDEslenC<-* +tC+p +F+C +g+ CI rswvCDGd+DCeD SDE ++C KIAA0816 117 PTCSPLDFHCDNGK-CIRRSWVCDGDNDCEDDSDE--QDC 153 PF00057.9.fs: domain 2 of 8, from 117 to 153: score 64.9, E = 2.7e-20 *->stCgpdeFqCgsgrrCIprswvCDGdpDCeDgSDEslenC<-* +tC+p +F+C +g+ CI rswvCDGd+DCeD SDE ++C KIAA0816 117 PTCSPLDFHCDNGK-CIRRSWVCDGDNDCEDDSDE--QDC 153 PF00057.9.fs: domain 3 of 8, from 156 to 191: score 50.5, E = 1.2e-15 *->stCgpdeFqCgsgrrCIprswvCDGdpDCeDgSDEslenC<-* + C++deF C++g CI ++w+CDGd+DC+D SDE +C KIAA0816 156 RECEEDEFPCQNGY-CIRSLWHCDGDNDCGDNSDE---QC 191 PF00057.9.ls: domain 3 of 8, from 156 to 191: score 52.4, E = 1.4e-12 *->stCgpdeFqCgsgrrCIprswvCDGdpDCeDgSDEslenC<-* + C++deF C++g CI ++w+CDGd+DC+D SDE +C KIAA0816 156 RECEEDEFPCQNGY-CIRSLWHCDGDNDCGDNSDE---QC 191 PF00057.9.ls: domain 4 of 8, from 194 to 230: score 64.4, E = 3.4e-16 *->stCgpdeFqCgsgrrCIprswvCDGdpDCeDgSDEslenC<-* ++C+ eF+C++g+ CI+ +w CDGd DC+DgSDE enC KIAA0816 194 RKCSDKEFRCSDGS-CIAEHWYCDGDTDCKDGSDE--ENC 230 PF00057.9.fs: domain 4 of 8, from 194 to 230: score 62.5, E = 1.6e-19 *->stCgpdeFqCgsgrrCIprswvCDGdpDCeDgSDEslenC<-* ++C+ eF+C++g+ CI+ +w CDGd DC+DgSDE enC KIAA0816 194 RKCSDKEFRCSDGS-CIAEHWYCDGDTDCKDGSDE--ENC 230 PF00057.9.fs: domain 5 of 8, from 237 to 273: score 48.2, E = 6.8e-15 *->stCgpdeFqCgsgrrCIprswvCDGdpDCeDgSDEslenC<-* ++C eFqC+ gr CI ++CDGd+DC+D+SDE +C KIAA0816 237 PPCNLEEFQCAYGR-CILDIYHCDGDDDCGDWSDE--SDC 273 PF00057.9.ls: domain 5 of 8, from 237 to 273: score 50.1, E = 7e-12 *->stCgpdeFqCgsgrrCIprswvCDGdpDCeDgSDEslenC<-* ++C eFqC+ gr CI ++CDGd+DC+D+SDE +C KIAA0816 237 PPCNLEEFQCAYGR-CILDIYHCDGDDDCGDWSDE--SDC 273 PF00057.9.ls: domain 6 of 8, from 277 to 313: score 54.5, E = 3.3e-13 *->stCgpdeFqCgsgrrCIprswvCDGdpDCeDgSDEslenC<-* +C+++eF C sg CI+ w+CDGd+DC+D+SDE nC KIAA0816 277 QPCRSGEFMCDSGL-CINAGWRCDGDADCDDQSDE--RNC 313 PF00057.9.fs: domain 6 of 8, from 277 to 313: score 52.6, E = 2.5e-16 *->stCgpdeFqCgsgrrCIprswvCDGdpDCeDgSDEslenC<-* +C+++eF C sg CI+ w+CDGd+DC+D+SDE nC KIAA0816 277 QPCRSGEFMCDSGL-CINAGWRCDGDADCDDQSDE--RNC 313 PF00057.9.fs: domain 7 of 8, from 316 to 352: score 59.2, E = 1.9e-18 *->stCgpdeFqCgsgrrCIprswvCDGdpDCeDgSDEslenC<-* s C + +F+C+sgr C+ sw+CDG++DC+D SDE enC KIAA0816 316 SMCTAEQFRCHSGR-CVRLSWRCDGEDDCADNSDE--ENC 352 PF00057.9.ls: domain 7 of 8, from 316 to 352: score 61.1, E = 3.4e-15 *->stCgpdeFqCgsgrrCIprswvCDGdpDCeDgSDEslenC<-* s C + +F+C+sgr C+ sw+CDG++DC+D SDE enC KIAA0816 316 SMCTAEQFRCHSGR-CVRLSWRCDGEDDCADNSDE--ENC 352 PF00057.9.fs: domain 8 of 8, from 358 to 397: score 49.2, E = 3.1e-15 *->stCgpdeFqCgsgrrCIprswvCDGdpDCeDgSDE.slenC<-* ++C+ d+F C +gr CI ++++C+G +DC+D SDE++++nC KIAA0816 358 PQCALDQFLCWNGR-CIGQRKLCNGVNDCGDNSDEsPQQNC 397 PF00057.9.ls: domain 8 of 8, from 358 to 397: score 51.2, E = 3.2e-12 *->stCgpdeFqCgsgrrCIprswvCDGdpDCeDgSDE.slenC<-* ++C+ d+F C +gr CI ++++C+G +DC+D SDE++++nC KIAA0816 358 PQCALDQFLCWNGR-CIGQRKLCNGVNDCGDNSDEsPQQNC 397 PF00008.17.fs: domain 6 of 11, from 406 to 441: score 29.7, E = 2.1e-07 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C+ nng+C +C++++g +C C+ Gy+l +G++C KIAA0816 406 CNVNNGGCAQ--KCQMVRGAVQCTCHTGYRLTEDGHTC 441 PF00008.17.ls: domain 3 of 8, from 406 to 441: score 31.6, E = 2.5e-06 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C+ nng+C +C++++g +C C+ Gy+l +G++C KIAA0816 406 CNVNNGGCAQ--KCQMVRGAVQCTCHTGYRLTEDGHTC 441 PF07645.6.ls: domain 1 of 1, from 443 to 481: score 32.7, E = 1.2e-06 *->DvDECadgtlhnCdDpdantvCvNtiGSFeCvarkdCpeGYeVpvse Dv+ECa+ + C + C+N +G F+C C+ GYe KIAA0816 443 DVNECAEEG--YC-----SQGCTNSEGAFQCW----CETGYE----- 473 nnedgtnC<-* +d+ C KIAA0816 474 LRPDRRSC 481 PF07645.6.fs: domain 3 of 6, from 443 to 481: score 31.0, E = 1.2e-08 *->DvDECadgtlhnCdDpdantvCvNtiGSFeCvarkdCpeGYeVpvse Dv+ECa+ + C + C+N +G F+C C+ GYe KIAA0816 443 DVNECAEEG--YC-----SQGCTNSEGAFQCW----CETGYE----- 473 nnedgtnC<-* +d+ C KIAA0816 474 LRPDRRSC 481 PF00058.8.ls: domain 1 of 19, from 528 to 569: score 41.5, E = 2.6e-09 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi ++++W+D+ l+ +i +a+lnGs++ ++s l++P g+avD++ KIAA0816 528 ELVFWSDVTLD---RILRANLNGSNVEEVVSTG--LESPGGLAVDWV 569 <-* KIAA0816 - - PF00058.8.fs: domain 1 of 20, from 528 to 569: score 39.6, E = 3.8e-11 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi ++++W+D+ l+ +i +a+lnGs++ ++s l++P g+avD++ KIAA0816 528 ELVFWSDVTLD---RILRANLNGSNVEEVVSTG--LESPGGLAVDWV 569 <-* KIAA0816 - - PF00058.8.ls: domain 2 of 19, from 571 to 612: score 56.7, E = 7.2e-14 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi ++lYWtDs++ +i+va+l+G++r++l+ ++ l++P++Ia++p KIAA0816 571 DKLYWTDSGTS---RIEVANLDGAHRKVLLWQN--LEKPRAIALHPM 612 <-* KIAA0816 - - PF00058.8.fs: domain 2 of 20, from 571 to 612: score 54.8, E = 1e-15 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi ++lYWtDs++ +i+va+l+G++r++l+ ++ l++P++Ia++p KIAA0816 571 DKLYWTDSGTS---RIEVANLDGAHRKVLLWQN--LEKPRAIALHPM 612 <-* KIAA0816 - - PF00058.8.fs: domain 3 of 20, from 614 to 656: score 48.0, E = 1.1e-13 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi g +YWtD+++ ++i++ ++Gs rr++ + l +Png+++D+ KIAA0816 614 GTIYWTDWGNT--PRIEASSMDGSGRRIIADTH--LFWPNGLTIDYA 656 <-* KIAA0816 - - PF00058.8.ls: domain 3 of 19, from 614 to 656: score 49.9, E = 7.8e-12 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi g +YWtD+++ ++i++ ++Gs rr++ + l +Png+++D+ KIAA0816 614 GTIYWTDWGNT--PRIEASSMDGSGRRIIADTH--LFWPNGLTIDYA 656 <-* KIAA0816 - - PF00058.8.ls: domain 4 of 19, from 658 to 699: score 52.8, E = 1e-12 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi +r+YW+D++ + i++a+l+Gs+r++++s+ l hP++I+v++ KIAA0816 658 RRMYWVDAKHH---VIERANLDGSHRKAVISQG--LPHPFAITVFED 699 <-* KIAA0816 - - PF00058.8.fs: domain 4 of 20, from 658 to 698: score 47.1, E = 2.1e-13 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDp< +r+YW+D++ + i++a+l+Gs+r++++s+ l hP++I+v++ KIAA0816 658 RRMYWVDAKHH---VIERANLDGSHRKAVISQG--LPHPFAITVFE 698 -* KIAA0816 - - PF00058.8.ls: domain 5 of 19, from 701 to 741: score 13.4, E = 0.041 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngI.avDp lYWtD+ ++ + s+++++G++ ++++ l+ P +I++++p KIAA0816 701 --LYWTDWHTK--SINSANKFTGKN-QEIIRNK--LHFPMDIhTLHP 740 i<-* + KIAA0816 741 Q 741 PF00008.17.ls: domain 5 of 8, from 750 to 784: score 20.5, E = 0.0055 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C +nng+C + C+++++ ytC Cp G f + + C KIAA0816 750 CGDNNGGCTH--LCLPSGQNYTCACPTG-FRKISSHAC 784 PF00058.8.fs: domain 6 of 20, from 833 to 874: score 44.3, E = 1.5e-12 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi +++YWtD+s++ +is+a+ +G+ + ++++ l++P+g+a+D++ KIAA0816 833 DHVYWTDVSTD---TISRAKWDGTGQEVVVDTS--LESPAGLAIDWV 874 <-* KIAA0816 - - PF00058.8.ls: domain 6 of 19, from 833 to 874: score 46.2, E = 1.1e-10 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi +++YWtD+s++ +is+a+ +G+ + ++++ l++P+g+a+D++ KIAA0816 833 DHVYWTDVSTD---TISRAKWDGTGQEVVVDTS--LESPAGLAIDWV 874 <-* KIAA0816 - - PF00058.8.fs: domain 7 of 20, from 876 to 917: score 42.9, E = 3.9e-12 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi ++lYWtD++++ +i+va+++Gs r +l+ e+ l+ P++I+v p KIAA0816 876 NKLYWTDAGTD---RIEVANTDGSMRTVLIWEN--LDRPRDIVVEPM 917 <-* KIAA0816 - - PF00058.8.ls: domain 7 of 19, from 876 to 917: score 44.8, E = 2.8e-10 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi ++lYWtD++++ +i+va+++Gs r +l+ e+ l+ P++I+v p KIAA0816 876 NKLYWTDAGTD---RIEVANTDGSMRTVLIWEN--LDRPRDIVVEPM 917 <-* KIAA0816 - - PF00058.8.fs: domain 8 of 20, from 919 to 961: score 50.1, E = 2.6e-14 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi g++YWtD++ ++i++a+++ s r +++s++ l +Png+a+D+ KIAA0816 919 GYMYWTDWGAS--PKIERAGMDASGRQVIISSN--LTWPNGLAIDYG 961 <-* KIAA0816 - - PF00058.8.ls: domain 8 of 19, from 919 to 961: score 52.0, E = 1.8e-12 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi g++YWtD++ ++i++a+++ s r +++s++ l +Png+a+D+ KIAA0816 919 GYMYWTDWGAS--PKIERAGMDASGRQVIISSN--LTWPNGLAIDYG 961 <-* KIAA0816 - - PF00058.8.ls: domain 9 of 19, from 963 to 1004: score 41.4, E = 2.9e-09 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi +rlYW D++ + +i+ a+l+Gs+r++l+ ++ l hP+g++++ + KIAA0816 963 QRLYWADAGMK---TIEFAGLDGSKRKVLIGSQ--LPHPFGLTLYGE 1004 <-* KIAA0816 - - PF00058.8.fs: domain 9 of 20, from 963 to 1002: score 37.1, E = 2.2e-10 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavD<- +rlYW D++ + +i+ a+l+Gs+r++l+ ++ l hP+g++++ KIAA0816 963 QRLYWADAGMK---TIEFAGLDGSKRKVLIGSQ--LPHPFGLTLY 1002 * KIAA0816 - - PF00058.8.fs: domain 10 of 20, from 1004 to 1045: score 29.2, E = 5e-08 *->grlYWtDsslrkIasisvad.lnGsdrrtlfsededlqhPngIavDp +r+YWtD+ ++ si++ad+l+G d r ++e+ l++ +I v++ KIAA0816 1004 ERIYWTDWQTK---SIQSADrLTGLD-RETLQEN--LENLMDIHVFH 1044 i<-* + KIAA0816 1045 R 1045 PF00058.8.ls: domain 10 of 19, from 1005 to 1045: score 26.2, E = 0.00011 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi r+YWtD+ ++ + s+++l+G d r ++e+ l++ +I v+++ KIAA0816 1005 -RIYWTDWQTK--SIQSADRLTGLD-RETLQEN--LENLMDIHVFHR 1045 <-* KIAA0816 - - PF00008.17.ls: domain 6 of 8, from 1054 to 1091: score 35.2, E = 2.1e-07 *->CspnngpCsngGtCvdtp..ggytCeCppGyfllytGkrC<-* C+ +ng+Cs+ C+++p+++g++C Cp G ll +Gk+C KIAA0816 1054 CAMENGGCSH--LCLRSPnpSGFSCTCPTGINLLSDGKTC 1091 PF00008.17.fs: domain 9 of 11, from 1054 to 1091: score 33.2, E = 2.1e-08 *->CspnngpCsngGtCvdtp..ggytCeCppGyfllytGkrC<-* C+ +ng+Cs+ C+++p+++g++C Cp G ll +Gk+C KIAA0816 1054 CAMENGGCSH--LCLRSPnpSGFSCTCPTGINLLSDGKTC 1091 PF00058.8.fs: domain 11 of 20, from 1141 to 1182: score 41.9, E = 7.9e-12 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi g++YW+Ds l+ +is+a+l+Gs + +++ lq+ +g+avD i KIAA0816 1141 GKVYWSDSTLH---RISRANLDGSQHEDIITTG--LQTTDGLAVDAI 1182 <-* KIAA0816 - - PF00058.8.ls: domain 11 of 19, from 1141 to 1182: score 43.8, E = 5.5e-10 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi g++YW+Ds l+ +is+a+l+Gs + +++ lq+ +g+avD i KIAA0816 1141 GKVYWSDSTLH---RISRANLDGSQHEDIITTG--LQTTDGLAVDAI 1182 <-* KIAA0816 - - PF00058.8.ls: domain 12 of 19, from 1184 to 1225: score 48.4, E = 2.3e-11 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi +++YWtD ++ +i+v +l+Gs r++l+ ++ l++P++I+++++ KIAA0816 1184 RKVYWTDTGTN---RIEVGNLDGSMRKVLVWQN--LDSPRAIVLYHE 1225 <-* KIAA0816 - - PF00058.8.fs: domain 12 of 20, from 1184 to 1225: score 46.5, E = 3.3e-13 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi +++YWtD ++ +i+v +l+Gs r++l+ ++ l++P++I+++++ KIAA0816 1184 RKVYWTDTGTN---RIEVGNLDGSMRKVLVWQN--LDSPRAIVLYHE 1225 <-* KIAA0816 - - PF00058.8.ls: domain 13 of 19, from 1227 to 1269: score 58.3, E = 2.3e-14 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi g++YWtD+++ a++++ +++Gsdr +l++++ l +Png++vD KIAA0816 1227 GFMYWTDWGEN--AKLERSGMDGSDRAVLINNN--LGWPNGLTVDKA 1269 <-* KIAA0816 - - PF00058.8.fs: domain 13 of 20, from 1227 to 1269: score 56.4, E = 3.3e-16 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi g++YWtD+++ a++++ +++Gsdr +l++++ l +Png++vD KIAA0816 1227 GFMYWTDWGEN--AKLERSGMDGSDRAVLINNN--LGWPNGLTVDKA 1269 <-* KIAA0816 - - PF00058.8.fs: domain 14 of 20, from 1271 to 1308: score 18.9, E = 6.7e-05 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIav<-* l W D+ ++ +i++adlnG++r+tl+s qhP g+++ KIAA0816 1271 SQLLWADAHTE---RIEAADLNGANRHTLVSPV---QHPYGLTL 1308 PF00058.8.ls: domain 14 of 19, from 1271 to 1311: score 19.1, E = 0.007 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi l W D+ ++ +i++adlnG++r+tl+s qhP g+++ + KIAA0816 1271 SQLLWADAHTE---RIEAADLNGANRHTLVSPV---QHPYGLTLLDS 1311 <-* KIAA0816 - - PF00058.8.ls: domain 15 of 19, from 1312 to 1353: score 8.0, E = 0.22 *->grlYWtDsslrkIasisvad.lnGsdrrtlfsededlqhPngI.avD ++YWtD+ +r si +ad+++Gs+ +l++++ l + +avD KIAA0816 1312 -YIYWTDWQTR---SIHRADkGTGSN-VILVRSN--LPGLMDMqAVD 1351 pi<-* KIAA0816 1352 RA 1353 PF00008.17.fs: domain 10 of 11, from 1361 to 1396: score 34.4, E = 9.9e-09 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C + ng+Cs+ C++ p+g++C Cp G +l ++Gk+C KIAA0816 1361 CGSRNGGCSH--LCLPRPSGFSCACPTGIQLKGDGKTC 1396 PF00008.17.ls: domain 7 of 8, from 1361 to 1396: score 36.3, E = 9.7e-08 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C + ng+Cs+ C++ p+g++C Cp G +l ++Gk+C KIAA0816 1361 CGSRNGGCSH--LCLPRPSGFSCACPTGIQLKGDGKTC 1396 PF00058.8.fs: domain 16 of 20, from 1445 to 1486: score 32.9, E = 3.9e-09 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi g++Y tD+ l+ i +adlnGs+ t++ l + +g+avD++ KIAA0816 1445 GKVYYTDVFLD---VIRRADLNGSNMETVIGRG--LKTTDGLAVDWV 1486 <-* KIAA0816 - - PF00058.8.ls: domain 16 of 19, from 1445 to 1486: score 34.8, E = 2.7e-07 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi g++Y tD+ l+ i +adlnGs+ t++ l + +g+avD++ KIAA0816 1445 GKVYYTDVFLD---VIRRADLNGSNMETVIGRG--LKTTDGLAVDWV 1486 <-* KIAA0816 - - PF00058.8.ls: domain 17 of 19, from 1488 to 1526: score 23.9, E = 0.00052 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi ++lYWtD + +i++ +l+Gs r++l+++ ++Ia +p+ KIAA0816 1488 RNLYWTDTGRN---TIEASRLDGSCRKVLINNS-----LDDIAAFPR 1526 <-* KIAA0816 - - PF00058.8.fs: domain 17 of 20, from 1488 to 1526: score 22.1, E = 7.1e-06 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi ++lYWtD + +i++ +l+Gs r++l+++ ++Ia +p+ KIAA0816 1488 RNLYWTDTGRN---TIEASRLDGSCRKVLINNS-----LDDIAAFPR 1526 <-* KIAA0816 - - PF00058.8.ls: domain 18 of 19, from 1528 to 1570: score 58.0, E = 2.8e-14 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi g+l+WtD++ a+i++a+l+Gs+r++l++ d l +Png+++D+ KIAA0816 1528 GYLFWTDWGHI--AKIERANLDGSERKVLINTD--LGWPNGLTLDYD 1570 <-* KIAA0816 - - PF00058.8.fs: domain 18 of 20, from 1528 to 1570: score 56.1, E = 4.1e-16 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIavDpi g+l+WtD++ a+i++a+l+Gs+r++l++ d l +Png+++D+ KIAA0816 1528 GYLFWTDWGHI--AKIERANLDGSERKVLINTD--LGWPNGLTLDYD 1570 <-* KIAA0816 - - PF00058.8.ls: domain 19 of 19, from 1572 to 1617: score 28.8, E = 1.8e-05 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIa.... +r+YW+D+ l+ +i++adlnG+ r+++ + ++hP++++++++ KIAA0816 1572 RRIYWVDAHLD---RIESADLNGKL-RQVLVGH--VSHPFALTqqdr 1612 .vDpi<-* ++++ KIAA0816 1613 wIYWT 1617 PF00058.8.fs: domain 19 of 20, from 1572 to 1608: score 27.7, E = 1.4e-07 *->grlYWtDsslrkIasisvadlnGsdrrtlfsededlqhPngIa<-* +r+YW+D+ l+ +i++adlnG+ r+++ + ++hP++++ KIAA0816 1572 RRIYWVDAHLD---RIESADLNGKL-RQVLVGH--VSHPFALT 1608 //