hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080502/iprscan-20080502-13494157/chunk_1/iprscan-20080502-13494157.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: KIAA0814 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF00008.17.ls EGF-like domain 326.5 4.3e-95 9 PF00008.17.fs EGF-like domain 310.1 3.6e-90 9 PF00560.23.ls Leucine Rich Repeat 249.5 6.7e-72 22 PF00560.23.fs Leucine Rich Repeat 210.0 5.2e-60 21 PF01462.9.fs Leucine rich repeat N-terminal domain 138.9 6e-41 5 PF01462.9.ls Leucine rich repeat N-terminal domain 145.3 1.5e-40 4 PF07974.3.ls EGF-like domain 127.7 3e-35 9 PF02210.14.fs Laminin G domain 114.6 4.2e-33 1 PF02210.14.ls Laminin G domain 116.5 6.9e-32 1 PF07974.3.fs EGF-like domain 112.4 1.2e-30 8 PF01463.14.fs Leucine rich repeat C-terminal domain 79.1 6.6e-24 5 PF00054.13.fs Laminin G domain 83.5 1.3e-23 1 PF01463.14.ls Leucine rich repeat C-terminal domain 88.9 1.4e-23 6 PF00054.13.ls Laminin G domain 85.3 1.7e-22 1 PF00053.14.fs Laminin EGF-like (Domains III and V) 37.7 2.8e-10 6 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF01462.9.fs 1/5 69 96 .. 1 34 [] 41.3 1.3e-11 PF01462.9.ls 1/4 69 96 .. 1 34 [] 43.1 8.8e-10 PF00560.23.ls 1/22 98 120 .. 1 24 [] 10.6 2.7 PF00560.23.fs 2/21 122 144 .. 1 24 [] 14.2 0.0079 PF00560.23.ls 2/22 122 144 .. 1 24 [] 16.0 0.12 PF00560.23.ls 3/22 146 168 .. 1 24 [] 9.6 4.2 PF00560.23.fs 4/21 170 192 .. 1 24 [] 12.4 0.024 PF00560.23.ls 4/22 170 192 .. 1 24 [] 14.3 0.42 PF00560.23.ls 5/22 194 216 .. 1 24 [] 13.0 0.96 PF00560.23.fs 5/21 194 216 .. 1 24 [] 11.2 0.053 PF00560.23.ls 6/22 218 240 .. 1 24 [] 11.2 2.1 PF01463.14.ls 1/6 275 300 .. 1 26 [] 24.9 0.00027 PF01463.14.fs 1/5 275 300 .. 1 26 [] 22.9 3.2e-06 PF01462.9.fs 2/5 315 342 .. 1 34 [] 31.6 1.1e-08 PF01462.9.ls 2/4 315 342 .. 1 34 [] 33.5 7e-07 PF00560.23.fs 9/21 368 390 .. 1 24 [] 14.9 0.005 PF00560.23.ls 9/22 368 390 .. 1 24 [] 16.8 0.074 PF00560.23.ls 10/22 392 414 .. 1 24 [] 16.5 0.092 PF00560.23.fs 10/21 392 414 .. 1 24 [] 14.6 0.0061 PF00560.23.ls 12/22 440 462 .. 1 24 [] 12.5 1.2 PF01463.14.fs 2/5 497 522 .. 1 26 [] 15.8 0.00054 PF01462.9.fs 3/5 540 567 .. 1 34 [] 30.6 2.2e-08 PF01462.9.ls 3/4 540 567 .. 1 34 [] 32.4 1.4e-06 PF00560.23.fs 14/21 594 616 .. 1 24 [] 11.9 0.033 PF00560.23.ls 15/22 594 616 .. 1 24 [] 13.8 0.58 PF00560.23.ls 16/22 618 640 .. 1 24 [] 11.2 2.1 PF00560.23.ls 17/22 642 664 .. 1 24 [] 9.8 3.9 PF00560.23.fs 17/21 666 688 .. 1 24 [] 12.0 0.031 PF00560.23.ls 18/22 666 688 .. 1 24 [] 13.9 0.54 PF01463.14.fs 3/5 723 748 .. 1 26 [] 16.6 0.0003 PF01462.9.fs 4/5 760 787 .. 1 34 [] 34.5 1.5e-09 PF01462.9.ls 4/4 760 787 .. 1 34 [] 36.3 9.7e-08 PF00560.23.fs 18/21 789 810 .. 1 24 [] 11.5 0.043 PF00560.23.ls 19/22 789 810 .. 1 24 [] 13.4 0.79 PF00560.23.ls 20/22 812 834 .. 1 24 [] 13.9 0.55 PF00560.23.fs 19/21 812 834 .. 1 24 [] 12.0 0.031 PF00560.23.ls 21/22 836 858 .. 1 24 [] 16.1 0.12 PF00560.23.fs 20/21 836 858 .. 1 24 [] 14.2 0.0077 PF00560.23.fs 21/21 860 882 .. 1 24 [] 14.9 0.0052 PF00560.23.ls 22/22 860 882 .. 1 24 [] 16.7 0.077 PF01463.14.fs 4/5 917 942 .. 1 26 [] 19.4 4e-05 PF01463.14.ls 4/6 917 942 .. 1 26 [] 21.4 0.003 PF07974.3.ls 1/9 956 988 .. 1 37 [] 21.8 0.0022 PF00008.17.ls 1/9 956 988 .. 1 38 [] 33.2 8.2e-07 PF00008.17.fs 1/9 956 988 .. 1 38 [] 31.4 6.7e-08 PF00008.17.fs 2/9 995 1029 .. 1 38 [] 35.7 4.2e-09 PF00008.17.ls 2/9 995 1029 .. 1 38 [] 37.5 4.2e-08 PF00008.17.fs 3/9 1036 1067 .. 1 38 [] 41.6 9e-11 PF00008.17.ls 3/9 1036 1067 .. 1 38 [] 43.5 6.9e-10 PF00008.17.ls 4/9 1074 1107 .. 1 38 [] 41.7 2.2e-09 PF00008.17.fs 4/9 1074 1107 .. 1 38 [] 39.9 2.8e-10 PF00008.17.fs 5/9 1114 1145 .. 1 38 [] 40.1 2.5e-10 PF00008.17.ls 5/9 1114 1145 .. 1 38 [] 41.9 2e-09 PF00008.17.fs 6/9 1159 1190 .. 1 38 [] 38.4 7.5e-10 PF00008.17.ls 6/9 1159 1190 .. 1 38 [] 40.2 6.7e-09 PF00054.13.ls 1/1 1222 1353 .. 1 159 [] 85.3 1.7e-22 PF02210.14.ls 1/1 1222 1350 .. 1 141 [] 116.5 6.9e-32 PF00054.13.fs 1/1 1222 1353 .. 1 159 [] 83.5 1.3e-23 PF02210.14.fs 1/1 1222 1350 .. 1 141 [] 114.6 4.2e-33 PF00008.17.ls 7/9 1368 1400 .. 1 38 [] 24.0 0.0005 PF00008.17.fs 8/9 1408 1438 .. 1 38 [] 32.8 2.8e-08 PF00008.17.ls 8/9 1408 1438 .. 1 38 [] 34.5 3.3e-07 PF00008.17.fs 9/9 1448 1479 .. 1 38 [] 28.1 5.7e-07 PF00008.17.ls 9/9 1448 1479 .. 1 38 [] 29.9 8.2e-06 Alignments of top-scoring domains: PF01462.9.fs: domain 1 of 5, from 69 to 96: score 41.3, E = 1.3e-11 *->aCpapCtCserytdglvVdCsgrgLtvavPrdlP<-* aCp CtCs + +VdC+g+gL+ avPr++P KIAA0814 69 ACPTKCTCS-----AASVDCHGLGLR-AVPRGIP 96 PF01462.9.ls: domain 1 of 4, from 69 to 96: score 43.1, E = 8.8e-10 *->aCpapCtCserytdglvVdCsgrgLtvavPrdlP<-* aCp CtCs + +VdC+g+gL+ avPr++P KIAA0814 69 ACPTKCTCS-----AASVDCHGLGLR-AVPRGIP 96 PF00560.23.ls: domain 1 of 22, from 98 to 120: score 10.6, E = 2.7 *->nLeeLdLsgCNpsltgslpss.l.nl<-* n e LdL++ N ++t + + ++ +l KIAA0814 98 NAERLDLDR-N-NIT-RITKMdFaGL 120 PF00560.23.fs: domain 2 of 21, from 122 to 144: score 14.2, E = 0.0079 *->nLeeLdLsgCNpsltgslpss.l.nl<-* nL++L+L++ N +++ ++ +++++l KIAA0814 122 NLRVLHLED-N-QVS-VIERGaFqDL 144 PF00560.23.ls: domain 2 of 22, from 122 to 144: score 16.0, E = 0.12 *->nLeeLdLsgCNpsltgslpss.l.nl<-* nL++L+L++ N +++ ++ +++++l KIAA0814 122 NLRVLHLED-N-QVS-VIERGaFqDL 144 PF00560.23.ls: domain 3 of 22, from 146 to 168: score 9.6, E = 4.2 *->nLeeLdLsgCNpsltgslpss.l.nl<-* +Le L+L+ N +l+ lp+ +++ KIAA0814 146 QLERLRLNK-N-KLQ-VLPELlFqST 168 PF00560.23.fs: domain 4 of 21, from 170 to 192: score 12.4, E = 0.024 *->nLeeLdLsgCNpsltgslpss.l.nl<-* +L+ LdLs N +++ +p ++++ KIAA0814 170 KLTRLDLSE-N-QIQ-GIPRKaFrGI 192 PF00560.23.ls: domain 4 of 22, from 170 to 192: score 14.3, E = 0.42 *->nLeeLdLsgCNpsltgslpss.l.nl<-* +L+ LdLs N +++ +p ++++ KIAA0814 170 KLTRLDLSE-N-QIQ-GIPRKaFrGI 192 PF00560.23.ls: domain 5 of 22, from 194 to 216: score 13.0, E = 0.96 *->nLeeLdLsgCNpsltgslpss.l.nl<-* +++L L++ N +++ +++++++ l KIAA0814 194 DVKNLQLDN-N-HIS-CIEDGaFrAL 216 PF00560.23.fs: domain 5 of 21, from 194 to 216: score 11.2, E = 0.053 *->nLeeLdLsgCNpsltgslpss.l.nl<-* +++L L++ N +++ +++++++ l KIAA0814 194 DVKNLQLDN-N-HIS-CIEDGaFrAL 216 PF00560.23.ls: domain 6 of 22, from 218 to 240: score 11.2, E = 2.1 *->nLeeLdLsgCNpsltgslpss.l.nl<-* Le+L L++ N +++ + + +++++ KIAA0814 218 DLEILTLNN-N-NIS-RILVTsFnHM 240 PF01463.14.ls: domain 1 of 6, from 275 to 300: score 24.9, E = 0.00027 *->dlrCasPeslrGqplldlppsdfsCp<-* +++C+ P +lrG++++d++ ++ +Cp KIAA0814 275 FTLCMAPVHLRGFNVADVQKKEYVCP 300 PF01463.14.fs: domain 1 of 5, from 275 to 300: score 22.9, E = 3.2e-06 *->dlrCasPeslrGqplldlppsdfsCp<-* +++C+ P +lrG++++d++ ++ +Cp KIAA0814 275 FTLCMAPVHLRGFNVADVQKKEYVCP 300 PF01462.9.fs: domain 2 of 5, from 315 to 342: score 31.6, E = 1.1e-08 *->aCpapCtCserytdglvVdCsgrgLtvavPrdlP<-* Cp pCtCs VdC+g+gL ++P lP KIAA0814 315 SCPSPCTCS-----NNIVDCRGKGLM-EIPANLP 342 PF01462.9.ls: domain 2 of 4, from 315 to 342: score 33.5, E = 7e-07 *->aCpapCtCserytdglvVdCsgrgLtvavPrdlP<-* Cp pCtCs VdC+g+gL ++P lP KIAA0814 315 SCPSPCTCS-----NNIVDCRGKGLM-EIPANLP 342 PF00560.23.fs: domain 9 of 21, from 368 to 390: score 14.9, E = 0.005 *->nLeeLdLsgCNpsltgslpss.l.nl<-* +L+ +d+s N +++ +++++++++l KIAA0814 368 KLKRIDISK-N-QIS-DIAPDaFqGL 390 PF00560.23.ls: domain 9 of 22, from 368 to 390: score 16.8, E = 0.074 *->nLeeLdLsgCNpsltgslpss.l.nl<-* +L+ +d+s N +++ +++++++++l KIAA0814 368 KLKRIDISK-N-QIS-DIAPDaFqGL 390 PF00560.23.ls: domain 10 of 22, from 392 to 414: score 16.5, E = 0.092 *->nLeeLdLsgCNpsltgslpss.l.nl<-* +L++L L+g N ++t +++++ +++l KIAA0814 392 SLTSLVLYG-N-KIT-EIAKGlFdGL 414 PF00560.23.fs: domain 10 of 21, from 392 to 414: score 14.6, E = 0.0061 *->nLeeLdLsgCNpsltgslpss.l.nl<-* +L++L L+g N ++t +++++ +++l KIAA0814 392 SLTSLVLYG-N-KIT-EIAKGlFdGL 414 PF00560.23.ls: domain 12 of 22, from 440 to 462: score 12.5, E = 1.2 *->nLeeLdLsgCNpsltgslpss.l.nl<-* nL L+L++ N +l+ +++++ + l KIAA0814 440 NLNLLSLYD-N-KLQ-TISKGlFaPL 462 PF01463.14.fs: domain 2 of 5, from 497 to 522: score 15.8, E = 0.00054 *->dlrCasPeslrGqplldlppsdfsCp<-* +rC+sP +l+ +++ ++ +++f C+ KIAA0814 497 GARCSSPRRLANKRISQIKSKKFRCS 522 PF01462.9.fs: domain 3 of 5, from 540 to 567: score 30.6, E = 2.2e-08 *->aCpapCtCserytdglvVdCsgrgLtvavPrdlP<-* Cp C+C+ g+ VdCs+++L ++P+ lP KIAA0814 540 VCPEKCRCE-----GTIVDCSNQKLV-RIPSHLP 567 PF01462.9.ls: domain 3 of 4, from 540 to 567: score 32.4, E = 1.4e-06 *->aCpapCtCserytdglvVdCsgrgLtvavPrdlP<-* Cp C+C+ g+ VdCs+++L ++P+ lP KIAA0814 540 VCPEKCRCE-----GTIVDCSNQKLV-RIPSHLP 567 PF00560.23.fs: domain 14 of 21, from 594 to 616: score 11.9, E = 0.033 *->nLeeLdLsgCNpsltgslpss.l.nl<-* nL++++Ls+ N ++ +++ ++++++ KIAA0814 594 NLRKINLSN-N-KI-KEVREGaFdGA 616 PF00560.23.ls: domain 15 of 22, from 594 to 616: score 13.8, E = 0.58 *->nLeeLdLsgCNpsltgslpss.l.nl<-* nL++++Ls+ N ++ +++ ++++++ KIAA0814 594 NLRKINLSN-N-KI-KEVREGaFdGA 616 PF00560.23.ls: domain 16 of 22, from 618 to 640: score 11.2, E = 2.1 *->nLeeLdLsgCNpsltgslpss.l.nl<-* +++eL L g N +l+ +++ +++l KIAA0814 618 SVQELMLTG-N-QLE-TVHGRvFrGL 640 PF00560.23.ls: domain 17 of 22, from 642 to 664: score 9.8, E = 3.9 *->nLeeLdLsgCNpsltgslpss.l.nl<-* L++L L++ N + g ++++++ +l KIAA0814 642 GLKTLMLRS-N-LI-GCVSNDtFaGL 664 PF00560.23.fs: domain 17 of 21, from 666 to 688: score 12.0, E = 0.031 *->nLeeLdLsgCNpsltgslpss.l.nl<-* +++ L+L++ N ++t ++ +++++ l KIAA0814 666 SVRLLSLYD-N-RIT-TITPGaFtTL 688 PF00560.23.ls: domain 18 of 22, from 666 to 688: score 13.9, E = 0.54 *->nLeeLdLsgCNpsltgslpss.l.nl<-* +++ L+L++ N ++t ++ +++++ l KIAA0814 666 SVRLLSLYD-N-RIT-TITPGaFtTL 688 PF01463.14.fs: domain 3 of 5, from 723 to 748: score 16.6, E = 0.0003 *->dlrCasPeslrGqplldlppsdfsCp<-* ++rC+ P l+ p+ d+ +df+C+ KIAA0814 723 NPRCQKPFFLKEIPIQDVAIQDFTCD 748 PF01462.9.fs: domain 4 of 5, from 760 to 787: score 34.5, E = 1.5e-09 *->aCpapCtCserytdglvVdCsgrgLtvavPrdlP<-* Cp +CtC ++vV Cs++gL+ a+Pr+ P KIAA0814 760 RCPEQCTCM-----ETVVRCSNKGLR-ALPRGMP 787 PF01462.9.ls: domain 4 of 4, from 760 to 787: score 36.3, E = 9.7e-08 *->aCpapCtCserytdglvVdCsgrgLtvavPrdlP<-* Cp +CtC ++vV Cs++gL+ a+Pr+ P KIAA0814 760 RCPEQCTCM-----ETVVRCSNKGLR-ALPRGMP 787 PF00560.23.fs: domain 18 of 21, from 789 to 810: score 11.5, E = 0.043 *->nLeeLdLsgCNpsltgslpssl.nl<-* ++eL+L+g N +lt +p +l+ l KIAA0814 789 DVTELYLEG-N-HLT-AVPRELsAL 810 PF00560.23.ls: domain 19 of 22, from 789 to 810: score 13.4, E = 0.79 *->nLeeLdLsgCNpsltgslpssl.nl<-* ++eL+L+g N +lt +p +l+ l KIAA0814 789 DVTELYLEG-N-HLT-AVPRELsAL 810 PF00560.23.ls: domain 20 of 22, from 812 to 834: score 13.9, E = 0.55 *->nLeeLdLsgCNpsltgslpss.l.nl<-* +L+ +dLs+ N s++ l + +++n+ KIAA0814 812 HLTLIDLSN-N-SIS-MLTNYtFsNM 834 PF00560.23.fs: domain 19 of 21, from 812 to 834: score 12.0, E = 0.031 *->nLeeLdLsgCNpsltgslpss.l.nl<-* +L+ +dLs+ N s++ l + +++n+ KIAA0814 812 HLTLIDLSN-N-SIS-MLTNYtFsNM 834 PF00560.23.ls: domain 21 of 22, from 836 to 858: score 16.1, E = 0.12 *->nLeeLdLsgCNpsltgslpss.l.nl<-* +L +L Ls+ N +l + +p++++++l KIAA0814 836 HLSTLILSY-N-RL-RCIPVHaFnGL 858 PF00560.23.fs: domain 20 of 21, from 836 to 858: score 14.2, E = 0.0077 *->nLeeLdLsgCNpsltgslpss.l.nl<-* +L +L Ls+ N +l + +p++++++l KIAA0814 836 HLSTLILSY-N-RL-RCIPVHaFnGL 858 PF00560.23.fs: domain 21 of 21, from 860 to 882: score 14.9, E = 0.0052 *->nLeeLdLsgCNpsltgslpss.l.nl<-* +L++L L+g N ++ s+p++++++l KIAA0814 860 SLRVLTLHG-N-DIS-SVPEGsFnDL 882 PF00560.23.ls: domain 22 of 22, from 860 to 882: score 16.7, E = 0.077 *->nLeeLdLsgCNpsltgslpss.l.nl<-* +L++L L+g N ++ s+p++++++l KIAA0814 860 SLRVLTLHG-N-DIS-SVPEGsFnDL 882 PF01463.14.fs: domain 4 of 5, from 917 to 942: score 19.4, E = 4e-05 *->dlrCasPeslrGqplldlpp.sdfsCp<-* +rC+sPe++++ +ll+++p++ f+C+ KIAA0814 917 IARCSSPEPMAD-RLLLTTPtHRFQCK 942 PF01463.14.ls: domain 4 of 6, from 917 to 942: score 21.4, E = 0.003 *->dlrCasPeslrGqplldlpp.sdfsCp<-* +rC+sPe++++ +ll+++p++ f+C+ KIAA0814 917 IARCSSPEPMAD-RLLLTTPtHRFQCK 942 PF07974.3.ls: domain 1 of 9, from 956 to 988: score 21.8, E = 0.0022 *->C....CngshGtCvspngtstpcgkCvCdsgyedkyqGadC<-* C +++C + +GtC + + +C C+ + y G+dC KIAA0814 956 ClsspCKN-NGTCTQDPVE---LYRCACPYS----YKGKDC 988 PF00008.17.ls: domain 1 of 9, from 956 to 988: score 33.2, E = 8.2e-07 *->CspnngpCsngGtCvdtp.ggytCeCppGyfllytGkrC<-* C + pC+n+GtC++ p + y+C Cp y+Gk+C KIAA0814 956 CLSS--PCKNNGTCTQDPvELYRCACPYS----YKGKDC 988 PF00008.17.fs: domain 1 of 9, from 956 to 988: score 31.4, E = 6.7e-08 *->CspnngpCsngGtCvdtp.ggytCeCppGyfllytGkrC<-* C + pC+n+GtC++ p + y+C Cp y+Gk+C KIAA0814 956 CLSS--PCKNNGTCTQDPvELYRCACPYS----YKGKDC 988 PF00008.17.fs: domain 2 of 9, from 995 to 1029: score 35.7, E = 4.2e-09 *->CspnngpCsngGtCvdtp...ggytCeCppGyfllytGkrC<-* C +n pC++gGtC+ ++++++g++C Cp G + G rC KIAA0814 995 CIQN--PCQHGGTCHLSDshkDGFSCSCPLG----FEGQRC 1029 PF00008.17.ls: domain 2 of 9, from 995 to 1029: score 37.5, E = 4.2e-08 *->CspnngpCsngGtCvdtp...ggytCeCppGyfllytGkrC<-* C +n pC++gGtC+ ++++++g++C Cp G + G rC KIAA0814 995 CIQN--PCQHGGTCHLSDshkDGFSCSCPLG----FEGQRC 1029 PF00008.17.fs: domain 3 of 9, from 1036 to 1067: score 41.6, E = 9e-11 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C +n C n++tCvd+ + y C+Cpp ytG+ C KIAA0814 1036 CEDN--DCENNATCVDGINNYVCICPPN----YTGELC 1067 PF00008.17.ls: domain 3 of 9, from 1036 to 1067: score 43.5, E = 6.9e-10 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C +n C n++tCvd+ + y C+Cpp ytG+ C KIAA0814 1036 CEDN--DCENNATCVDGINNYVCICPPN----YTGELC 1067 PF00008.17.ls: domain 4 of 9, from 1074 to 1107: score 41.7, E = 2.2e-09 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C p+ + C++ ++C++++ g++CeC pG y+Gk C KIAA0814 1074 CVPELNLCQHEAKCIPLDKGFSCECVPG----YSGKLC 1107 PF00008.17.fs: domain 4 of 9, from 1074 to 1107: score 39.9, E = 2.8e-10 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C p+ + C++ ++C++++ g++CeC pG y+Gk C KIAA0814 1074 CVPELNLCQHEAKCIPLDKGFSCECVPG----YSGKLC 1107 PF00008.17.fs: domain 5 of 9, from 1114 to 1145: score 40.1, E = 2.5e-10 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C + C +g++Cvdt +gytC Cp+G ++G++C KIAA0814 1114 CVAH--KCRHGAQCVDTINGYTCTCPQG----FSGPFC 1145 PF00008.17.ls: domain 5 of 9, from 1114 to 1145: score 41.9, E = 2e-09 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C + C +g++Cvdt +gytC Cp+G ++G++C KIAA0814 1114 CVAH--KCRHGAQCVDTINGYTCTCPQG----FSGPFC 1145 PF00008.17.fs: domain 6 of 9, from 1159 to 1190: score 38.4, E = 7.5e-10 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C++ C+ng++C+ +++++tC+CppG ++G+rC KIAA0814 1159 CDQY--ECQNGAQCIVVQQEPTCRCPPG----FAGPRC 1190 PF00008.17.ls: domain 6 of 9, from 1159 to 1190: score 40.2, E = 6.7e-09 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C++ C+ng++C+ +++++tC+CppG ++G+rC KIAA0814 1159 CDQY--ECQNGAQCIVVQQEPTCRCPPG----FAGPRC 1190 PF00054.13.ls: domain 1 of 1, from 1222 to 1353: score 85.3, E = 1.7e-22 *->FRTtepsGlLllgYnGtqterrskkeigdDFlaleLvdGrlevsydl ++T + +G+Ll Y G+++ aleL G++++ yd KIAA0814 1222 VATDKDNGILL--YKGDNDPL-----------ALELYQGHVRLVYDS 1255 GsgrlrpavvrsgdkvlnDGkWHsvelerngrsgtLsVdgearskktLgG s p ++++ ++++nDG+ Hsvel+ ++ ++L Vd+ + KIAA0814 1256 LSS---PPTTVYSVETVNDGQFHSVELVTLNQTLNLVVDKGTP------- 1295 svvtgesplgattesttLdvdgkLyvGGlPeldqavkarrlaisp..... + lg++++ + + + +Ly+GG+P +++ +++l+ ++++ + KIAA0814 1296 ------KSLGKLQKQPAVGINSPLYLGGIP---TSTGLSALRQGTdrplg 1336 sfkGCirdviingkpld<-* +f+GCi++v in++ +d KIAA0814 1337 GFHGCIHEVRINNELQD 1353 PF02210.14.ls: domain 1 of 1, from 1222 to 1350: score 116.5, E = 6.9e-32 *->FRTatqpnGlLlyaggk.glpdradpksdKflaLeLvdGrlvlrydl + T ++nG+Lly g+++ laLeL +G+++l+yd KIAA0814 1222 VAT-DKDNGILLYKGDNdP------------LALELYQGHVRLVYDS 1255 Gsgg.vlltsg.plnDGqWHtVsverngrsvtLsVDgg.vv.g.spgssd s+++++++s +++nDGq H+V+++ ++++ L+VD+g++ + + ++++ KIAA0814 1256 LSSPpTTVYSVeTVNDGQFHSVELVTLNQTLNLVVDKGtPKsLgKLQKQP 1305 tlslnlngplylGGlpesskssllrliaaqnlvtvs.gFvGCirnvring + +n+plylGG+p s ++s+lr+ + +gF+GCi +vrin+ KIAA0814 1306 --AVGINSPLYLGGIPTSTGLSALRQGTDRP----LgGFHGCIHEVRINN 1349 e<-* e KIAA0814 1350 E 1350 PF00054.13.fs: domain 1 of 1, from 1222 to 1353: score 83.5, E = 1.3e-23 *->FRTtepsGlLllgYnGtqterrskkeigdDFlaleLvdGrlevsydl ++T + +G+Ll Y G+++ aleL G++++ yd KIAA0814 1222 VATDKDNGILL--YKGDNDPL-----------ALELYQGHVRLVYDS 1255 GsgrlrpavvrsgdkvlnDGkWHsvelerngrsgtLsVdgearskktLgG s p ++++ ++++nDG+ Hsvel+ ++ ++L Vd+ + KIAA0814 1256 LSS---PPTTVYSVETVNDGQFHSVELVTLNQTLNLVVDKGTP------- 1295 svvtgesplgattesttLdvdgkLyvGGlPeldqavkarrlaisp..... + lg++++ + + + +Ly+GG+P +++ +++l+ ++++ + KIAA0814 1296 ------KSLGKLQKQPAVGINSPLYLGGIP---TSTGLSALRQGTdrplg 1336 sfkGCirdviingkpld<-* +f+GCi++v in++ +d KIAA0814 1337 GFHGCIHEVRINNELQD 1353 PF02210.14.fs: domain 1 of 1, from 1222 to 1350: score 114.6, E = 4.2e-33 *->FRTatqpnGlLlyaggk.glpdradpksdKflaLeLvdGrlvlrydl + T ++nG+Lly g+++ laLeL +G+++l+yd KIAA0814 1222 VAT-DKDNGILLYKGDNdP------------LALELYQGHVRLVYDS 1255 Gsgg.vlltsg.plnDGqWHtVsverngrsvtLsVDgg.vv.g.spgssd s+++++++s +++nDGq H+V+++ ++++ L+VD+g++ + + ++++ KIAA0814 1256 LSSPpTTVYSVeTVNDGQFHSVELVTLNQTLNLVVDKGtPKsLgKLQKQP 1305 tlslnlngplylGGlpesskssllrliaaqnlvtvs.gFvGCirnvring + +n+plylGG+p s ++s+lr+ + +gF+GCi +vrin+ KIAA0814 1306 --AVGINSPLYLGGIPTSTGLSALRQGTDRP----LgGFHGCIHEVRINN 1349 e<-* e KIAA0814 1350 E 1350 PF00008.17.ls: domain 7 of 9, from 1368 to 1400: score 24.0, E = 0.0005 *->CspnngpCsngGtCvdtp.ggytCeCppGyfllytGkrC<-* C + + C++ G C+++++++ CeC pG +tG+ C KIAA0814 1368 CKSCT-VCKH-GLCRSVEkDSVVCECRPG----WTGPLC 1400 PF00008.17.fs: domain 8 of 9, from 1408 to 1438: score 32.8, E = 2.8e-08 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C + C++ G+Cv t+++y+C+C++G y G+ C KIAA0814 1408 CLGH--RCHH-GKCVATGTSYMCKCAEG----YGGDLC 1438 PF00008.17.ls: domain 8 of 9, from 1408 to 1438: score 34.5, E = 3.3e-07 *->CspnngpCsngGtCvdtpggytCeCppGyfllytGkrC<-* C + C++ G+Cv t+++y+C+C++G y G+ C KIAA0814 1408 CLGH--RCHH-GKCVATGTSYMCKCAEG----YGGDLC 1438 PF00008.17.fs: domain 9 of 9, from 1448 to 1479: score 28.1, E = 5.7e-07 *->CspnngpCsngGtCvdtp.ggytCeCppGyfllytGkrC<-* Cs C++ G+C+ +++g+++C C+pG ++G++C KIAA0814 1448 CSAF--KCHH-GQCHISDqGEPYCLCQPG----FSGEHC 1479 PF00008.17.ls: domain 9 of 9, from 1448 to 1479: score 29.9, E = 8.2e-06 *->CspnngpCsngGtCvdtp.ggytCeCppGyfllytGkrC<-* Cs C++ G+C+ +++g+++C C+pG ++G++C KIAA0814 1448 CSAF--KCHH-GQCHISDqGEPYCLCQPG----FSGEHC 1479 //