hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-11083608/chunk_1/iprscan-20080502-11083608.nocrc
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Query sequence: KIAA0720
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
PF00621.11.fs RhoGEF domain                                   62.0      4e-18   2
PF00621.11.ls RhoGEF domain                                   63.6    5.9e-16   1
PF00169.19.fs PH domain                                       33.2    1.2e-09   1
PF00169.19.ls PH domain                                       35.2    2.2e-07   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PF00621.11.ls   1/1     425   612 ..     1   207 []    63.6  5.9e-16
PF00621.11.fs   1/2     425   482 ..     1    60 [.    36.3  1.7e-10
PF00621.11.fs   2/2     517   612 ..   101   207 .]    25.7  2.3e-07
PF00169.19.ls   1/1     670   769 ..     1    92 []    35.2  2.2e-07
PF00169.19.fs   1/1     670   769 ..     1    92 []    33.2  1.2e-09

Alignments of top-scoring domains:
PF00621.11.ls: domain 1 of 1, from 425 to 612: score 63.6, E = 5.9e-16
                   *->vlkElleTEkkYvrdLeildnvymkpLreaaisskplLtpddietiF
                      ++ Ell+TE+ Y+r L+ ++n ++  L++ + s   lL   ++e +F
    KIAA0720   425    AVWELLHTEASYIRKLRVIINLFLCCLLNLQESG--LLCEVEAERLF 469  

                   sNiediyefhreFLkssLearisssnfedlDekkiepsaqrl...GdlFl
                   sNi++i ++hr++  s + ++++              +++ l ++Gd + 
    KIAA0720   470 SNIPEIAQLHRRLWASVMAPVLEKA-----------RRTRALlqpGDFLK 508  

                   elkaef...lqvYgeYcsnkpyAqelleklrqaasnpqFaefldeveass
                    + + f++ +++Y +Yc   +  +e  + l+    n+ F+  +   e+++
    KIAA0720   509 GF-KMFgslFKPYIRYCMEEEGCMEYMRGLL--RDNDLFRAYITWAEKHP 555  

                   ntgAkddavkltLqsLLlkPvqRilrYpLLLkeLLkhtpegedssesedL
                   ++       +l+L++ L kP qR+++YpLLLk  L +t    +   +e  
    KIAA0720   556 QCQ------RLKLSDMLAKPHQRLTKYPLLLKSVLRKTE---EPRAKEAV 596  

                   kkaldalqdlaksiNe<-*
                   ++ +  ++++++++N+   
    KIAA0720   597 VAMIGSVERFIHHVNA    612  

PF00621.11.fs: domain 1 of 2, from 425 to 482: score 36.3, E = 1.7e-10
                   *->vlkElleTEkkYvrdLeildnvymkpLreaaisskplLtpddietiF
                      ++ Ell+TE+ Y+r L+ ++n ++  L++ + s   lL   ++e +F
    KIAA0720   425    AVWELLHTEASYIRKLRVIINLFLCCLLNLQESG--LLCEVEAERLF 469  

                   sNiediyefhreF<-*
                   sNi++i ++hr++   
    KIAA0720   470 SNIPEIAQLHRRL    482  

PF00621.11.fs: domain 2 of 2, from 517 to 612: score 25.7, E = 2.3e-07
                   *->lqvYgeYcsnkpyAqelleklrqaasnpqFaefldeveassntgAkd
                      +++Y +Yc   +  +e  + l+    n+ F+  +   e+++++    
    KIAA0720   517    FKPYIRYCMEEEGCMEYMRGLL--RDNDLFRAYITWAEKHPQCQ--- 558  

                   davkltLqsLLlkPvqRilrYpLLLkeLLkhtpegedssesedLkkalda
                      +l+L++ L kP qR+++YpLLLk  L +t    +   +e  ++ +  
    KIAA0720   559 ---RLKLSDMLAKPHQRLTKYPLLLKSVLRKTE---EPRAKEAVVAMIGS 602  

                   lqdlaksiNe<-*
                   ++++++++N+   
    KIAA0720   603 VERFIHHVNA    612  

PF00169.19.ls: domain 1 of 1, from 670 to 769: score 35.2, E = 2.2e-07
                   *->vikeGwLlkkggkkswkkRyfvLfddvLlyykdkk.....kkpkgsi
                      +  eG L++k+gk s  ++y++Lf+d Ll  k  k+ +++   +  +
    KIAA0720   670    LLLEGSLRMKEGKDSKMDVYCFLFTDLLLVTKAVKkaertRVIRPPL 716  

                   pLsgiqvtkvpdnkrkncFeirt.dr.....etlllqaeseeerkeWvka
                    +++i ++++ d   + +F ++  ++ ++    +++qa+ +  ++ Wv+ 
    KIAA0720   717 LVDKIVCRELRD---PGSFLLIYlNEfhsavGAYTFQASGQALCRGWVDT 763  

                   iqsair<-*
                   i +a+    
    KIAA0720   764 IYNAQN    769  

PF00169.19.fs: domain 1 of 1, from 670 to 769: score 33.2, E = 1.2e-09
                   *->vikeGwLlkkggkkswkkRyfvLfddvLlyykdkk.....kkpkgsi
                      +  eG L++k+gk s  ++y++Lf+d Ll  k  k+ +++   +  +
    KIAA0720   670    LLLEGSLRMKEGKDSKMDVYCFLFTDLLLVTKAVKkaertRVIRPPL 716  

                   pLsgiqvtkvpdnkrkncFeirt.dr.....etlllqaeseeerkeWvka
                    +++i ++++ d   + +F ++  ++ ++    +++qa+ +  ++ Wv+ 
    KIAA0720   717 LVDKIVCRELRD---PGSFLLIYlNEfhsavGAYTFQASGQALCRGWVDT 763  

                   iqsair<-*
                   i +a+    
    KIAA0720   764 IYNAQN    769  

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