hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/smart.HMMs.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-11033257/chunk_1/iprscan-20080502-11033257.nocrc
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Query sequence: KIAA0717
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model     Description                                   Score    E-value  N 
--------  -----------                                   -----    ------- ---
SM00174                                                 135.3    6.6e-36   1
SM00225                                                 128.9    5.4e-34   2
SM00175                                                 -28.2    1.6e-06   1
SM00173                                                 -42.6    0.00017   1

Parsed for domains:
Model     Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------  ------- ----- -----    ----- -----      -----  -------
SM00173     1/1      36   234 ..     1   167 []   -42.6  0.00017
SM00175     1/1      39   234 ..     1   172 []   -28.2  1.6e-06
SM00174     1/1      41   234 ..     1   180 []   135.3  6.6e-36
SM00225     1/2     290   496 ..     1   114 []    68.0  1.2e-15
SM00225     2/2     524   622 ..     1   114 []    60.9  1.6e-13

Alignments of top-scoring domains:
SM00173: domain 1 of 1, from 36 to 234: score -42.6, E = 0.00017
                   *->mreYKlVVlGgGGVGKSALTiQ......FiqghFvdeYDPTI..EDS
                      +++ K VV+G+  VGK+ L   +  + +++q + + ++ PT    D+
    KIAA0717    36    VETIKCVVVGDNAVGKTRLICAracnatLTQYQLLATHVPTVwaIDQ 82   

                   Yr..Kqi......eiDgevalLDILDTAGQeEFsAMRdqYmRtG..eGFl
                   Yr  +++ +++++++D+  + L   DT G +      d  +  G+++  +
    KIAA0717    83 YRvcQEVlersrdVVDDVSVSLRLWDTFGDHH----KDRRFAYGrsDVVV 128  

                   LVYSitsrqSFeeikkf.reqIlRVKdrddvPivLVGNKcDLen......
                   L++Si + +S +++k++ +  I     r   P++LVG   DL   + +  
    KIAA0717   129 LCFSIANPNSLHHVKTMwYPEIKHFCPR--APVILVGCQLDLRYadleav 176  

                   .............eRqVsteEGkeLAkqlncpFlEtSAKerinVdeaFyd
                   ++ +++  ++ ++      e G+e+Ak+l++p++EtS  ++  + ++F  
    KIAA0717   177 nrarrplarpikpNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDN 226  

                   LVReirks<-*
                    +R +  s   
    KIAA0717   227 AIRAALIS    234  

SM00175: domain 1 of 1, from 39 to 234: score -28.2, E = 1.6e-06
                   *->FKiilIGDSGVGKSsLLsR......FtddkFsedsksTI.GVD.Fkt
                       K +++GD +VGK+ L++ +  + + t  +    + +T+  +D++++
    KIAA0717    39    IKCVVVGDNAVGKTRLICAracnatLTQYQLLATHVPTVwAIDqYRV 85   

                   ktiev.......dGkrvKLQIWDTAGQE....RFRSiTssYYRGAvGalL
                   +   ++++++  d+  v L +WDT G  ++++RF       Y  ++ ++L
    KIAA0717    86 CQEVLersrdvvDDVSVSLRLWDTFGDHhkdrRFA------YGRSDVVVL 129  

                   VYDiTnreSFenlkn.WlkelreyadpppenvvimLVGNKsDLee..qRq
                   ++ i n++S  ++k  W  e++  ++      +++LVG+  DL+  +  +
    KIAA0717   130 CFSIANPNSLHHVKTmWYPEIKHFCPR----APVILVGCQLDLRYadLEA 175  

                   Vst.................EeaekficDcAeehgllFifETSAKtntNV
                   V++ +++  ++ ++++  ++E +++     A+e+g++++ ETS  + + +
    KIAA0717   176 VNRarrplarpikpneilppEKGREV----AKELGIPYY-ETSVVAQFGI 220  

                   eeAFeelakkIlkr<-*
                   +++F + ++  l     
    KIAA0717   221 KDVFDNAIRAALIS    234  

SM00174: domain 1 of 1, from 41 to 234: score 135.3, E = 6.6e-36
                   *->lVvVGDGaVGKTCLLisYTtnaFPedY......VPTVF..ENYsadv
                      +VvVGD aVGKT L  + + na  ++Y+   ++VPTV   + Y ++ 
    KIAA0717    41    CVVVGDNAVGKTRLICARACNATLTQYqllathVPTVWaiDQYRVCQ 87   

                   ev.......pDgkpvnLgLWDTAGQEdYDRLRPLSYPqtDVfLiCFSVds
                   ev +++++  D+  v+L LWDT G  d    R   Y  +DV+ +CFS+ +
    KIAA0717    88 EVlersrdvVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIAN 135  

                   paSfeNVkeKWyPEvkhfcPnvPiiLVGtKlDLR.nDedtleelsekkqe
                   p+S+  Vk++WyPE+khfcP +P+iLVG++lDLR  D +++++ +++   
    KIAA0717   136 PNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRyADLEAVNRARRPLAR 185  

                   Pvt......teqGeanskialAkeIGAvkYlECSAltqeGvkeVFeeAir
                   P+++++  ++e+G++     +Ake+G   Y E+S   q G+k+VF+ Air
    KIAA0717   186 PIKpneilpPEKGRE-----VAKELGI-PYYETSVVAQFGIKDVFDNAIR 229  

                   aaLnk<-*
                   aaL +   
    KIAA0717   230 AALIS    234  

SM00225: domain 1 of 2, from 290 to 496: score 68.0, E = 1.2e-15
                   *->cDvtlvvggdlggdnaegkkfhasqHkavLaacrrdSpyFkalfes.
                       Dv+lv ++        +++++a  Hk +L+++   S+ F++lf+ +
    KIAA0717   290    ADVILVLQE--------RVRIFA--HKIYLSTS---SSKFYDLFLMd 323  

                   ..................................................
                    ++++ ++++++++++++++++++++++++++++++++   +  + +  +
    KIAA0717   324 lsegelggpsepggthpedhqghsdqhhhhhhhhhgrdfllraasfdvce 373  

                   ..................................................
                   + ++ +++++ + + +++++  ++++++  +++++  ++ ++   + +++
    KIAA0717   374 svdeaggsgpaglrastsdgilrgngtgylpgrgrvlsswsrafvsiqee 423  

                   ...............ieldDeallievspeaFralLnflYt.kldlpeed
                     +++ + +++    + +d      +++p  Fra+L++lYt++ld +e  
    KIAA0717   424 maedpltyksrlmvvVKMDS-----SIQPGPFRAVLKYLYTgELDENER- 467  

                   venveelLelAdfldSYGqip.lvelCeefllknl<-*
                     +++++ ++A++l    ++ +l+ ++ ++l +     
    KIAA0717   468 --DLMHIAHIAELL----EVFdLRMMVANILNNEA    496  

SM00225: domain 2 of 2, from 524 to 622: score 60.9, E = 1.6e-13
                   *->cDvtlvvggdlggdnaegkkfhasqHkavLaacrrdSpyFkalfes.
                      +Dvt++ ++           ++a  Hk +L ++   ++   a+f ++
    KIAA0717   524    SDVTFILDD---------GTISA--HKPLLISS---CDWMAAMFGGp 556  

                   ........ieldDeallievspeaFralLnflYt.kldlpeedvenveel
                     +++++++ ++        s +++ra+L++lYt+ +  +++  ++ ++l
    KIAA0717   557 fvesstreVVFPY------TSKSCMRAVLEYLYTgMFTSSPD--LDDMKL 598  

                   LelAdfldSYGqip.lvelCeefllknl<-*
                   + lA++l    ++p+lv l e++ ++ l   
    KIAA0717   599 IILANRL----CLPhLVALTEQYTVTGL    622  

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