hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-08220169/chunk_1/iprscan-20080502-08220169.nocrc
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Query sequence: KIAA0623
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
PF00069.15.ls Protein kinase domain                       284.0    2.7e-82   1
PF00069.15.fs Protein kinase domain                       282.1      1e-81   1
PF07714.7.fs Protein tyrosine kinase                     122.3    2.2e-35   1
PF07714.7.ls Protein tyrosine kinase                     123.3    6.3e-34   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
PF00069.15.fs   1/1      73   335 ..     1   287 []   282.1    1e-81
PF07714.7.fs   1/1      73   269 ..     1   207 [.   122.3  2.2e-35
PF00069.15.ls   1/1      73   335 ..     1   287 []   284.0  2.7e-82
PF07714.7.ls   1/1      73   335 ..     1   272 []   123.3  6.3e-34

Alignments of top-scoring domains:
PF00069.15.fs: domain 1 of 1, from 73 to 335: score 282.1, E = 1e-81
                   *->yelleklGsGsfGtVykakhkgtgk.iVAvKiikkrkekskkdktar
                      y +   +G G+f++V++++h+   + +VA+K i+k++ ++++    +
    KIAA0623    73    YSKRDLVGHGAFAVVFRGRHRQKTDwEVAIKSINKKNLSKSQ----I 115  

                   rl.sEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrvldLfdyl
                   +l+ Ei+ilk+L+H+NIv l+dv e ++++ lV+Eyc+gG    dL dyl
    KIAA0623   116 LLgKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGG----DLADYL 161  

                   setrrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldnn
                   +   +kg+l  sed+++ ++ Qi+ ++  LHs+giiHRDLKP+NILl+  
    KIAA0623   162 Q---AKGTL--SEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYA 206  

                   gvvda.....flKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllggn
                   +  +++ ++ ++KiaDFG+A+   ++s+  + t++G+p YmAPEv++ ++
    KIAA0623   207 NRRKSsvsgiRIKIADFGFARY--LhSNMmAATLCGSPMYMAPEVIM-SQ 253  

                   gygtkvDvWSlGvilyelltGkpPFsgevqds.ldqlqlirkilgpplef
                   +y+ k+D WS+G ++y+ l GkpPF+     s+ d +  ++k+++  +++
    KIAA0623   254 HYDAKADLWSIGTVIYQCLVGKPPFQAN---SpQDLRMFYEKNRSLMPSI 300  

                   dspewdsisrsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf
                   +++++               + +  L+ ++L+++ ++R  +e  + HP++
    KIAA0623   301 PRETS---------------PYLANLLLGLLQRNQKDRMDFEAFFSHPFL 335  

                   <-*
                      
    KIAA0623     -     -    

PF07714.7.fs: domain 1 of 1, from 73 to 269: score 122.3, E = 2.2e-35
                   *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtL.keigaseeei
                       ++    G+GaF +V++G+ +   ++t+ +VA+K+++k+ + s +  
    KIAA0623    73    YSKRDLVGHGAFAVVFRGRHR---QKTDWEVAIKSInKK-NLSKS-- 113  

                   eredFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGd
                    +  + +E++i+k+l +H+NiV L+ v      +    +++V+Ey+ gGd
    KIAA0623   114 -QILLGKEIKILKEL-QHENIVALYDVQEL-PNS----VFLVMEYCNGGD 156  

                   LldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcLV
                   L d+L++   ++ L+  ++  f +QiA++M  L+sk+++HRDL   N+L+
    KIAA0623   157 LADYLQA---KGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILL 203  

                   se........nl.vVKIsDFGLaRdiynddyY.vrkkgggklPvkWmAPE
                   s  ++++++ ++  +KI+DFG aR++      ++ + + +  P   mAPE
    KIAA0623   204 SYanrrkssvSGiRIKIADFGFARYL----HSnMMAATLCGSPM-YMAPE 248  

                   slkygkFtskSDVWSFGVlLW<-*
                   +++   +  k D WS G +++   
    KIAA0623   249 VIMSQHYDAKADLWSIGTVIY    269  

PF00069.15.ls: domain 1 of 1, from 73 to 335: score 284.0, E = 2.7e-82
                   *->yelleklGsGsfGtVykakhkgtgk.iVAvKiikkrkekskkdktar
                      y +   +G G+f++V++++h+   + +VA+K i+k++ ++++    +
    KIAA0623    73    YSKRDLVGHGAFAVVFRGRHRQKTDwEVAIKSINKKNLSKSQ----I 115  

                   rl.sEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrvldLfdyl
                   +l+ Ei+ilk+L+H+NIv l+dv e ++++ lV+Eyc+gG    dL dyl
    KIAA0623   116 LLgKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGG----DLADYL 161  

                   setrrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldnn
                   +   +kg+l  sed+++ ++ Qi+ ++  LHs+giiHRDLKP+NILl+  
    KIAA0623   162 Q---AKGTL--SEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYA 206  

                   gvvda.....flKiaDFGlAkklst.sss.lttfvGTpwYmAPEvllggn
                   +  +++ ++ ++KiaDFG+A+   ++s+  + t++G+p YmAPEv++ ++
    KIAA0623   207 NRRKSsvsgiRIKIADFGFARY--LhSNMmAATLCGSPMYMAPEVIM-SQ 253  

                   gygtkvDvWSlGvilyelltGkpPFsgevqds.ldqlqlirkilgpplef
                   +y+ k+D WS+G ++y+ l GkpPF+     s+ d +  ++k+++  +++
    KIAA0623   254 HYDAKADLWSIGTVIYQCLVGKPPFQAN---SpQDLRMFYEKNRSLMPSI 300  

                   dspewdsisrsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf
                   +++++               + +  L+ ++L+++ ++R  +e  + HP++
    KIAA0623   301 PRETS---------------PYLANLLLGLLQRNQKDRMDFEAFFSHPFL 335  

                   <-*
                      
    KIAA0623     -     -    

PF07714.7.ls: domain 1 of 1, from 73 to 335: score 123.3, E = 6.3e-34
                   *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtL.keigaseeei
                       ++    G+GaF +V++G+ +   ++t+ +VA+K+++k+ + s +  
    KIAA0623    73    YSKRDLVGHGAFAVVFRGRHR---QKTDWEVAIKSInKK-NLSKS-- 113  

                   eredFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGd
                    +  + +E++i+k+l +H+NiV L+ v      +    +++V+Ey+ gGd
    KIAA0623   114 -QILLGKEIKILKEL-QHENIVALYDVQEL-PNS----VFLVMEYCNGGD 156  

                   LldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcLV
                   L d+L++   ++ L+  ++  f +QiA++M  L+sk+++HRDL   N+L+
    KIAA0623   157 LADYLQA---KGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILL 203  

                   se........nl.vVKIsDFGLaRdiynddyY.vrkkgggklPvkWmAPE
                   s  ++++++ ++  +KI+DFG aR++      ++ + + +  P   mAPE
    KIAA0623   204 SYanrrkssvSGiRIKIADFGFARYL----HSnMMAATLCGSPM-YMAPE 248  

                   slkygkFtskSDVWSFGVlLWEiftlGeqPFYpgmsneevlellyedGyR
                   +++   +  k D WS G +++  +  G++P ++  s+++ l ++ye+++ 
    KIAA0623   249 VIMSQHYDAKADLWSIGTVIYQCLV-GKPP-FQANSPQD-LRMFYEKNRS 295  

                   Lpr..PenCPdelYdlMlqCWaedPedRPtFsel..veeL<-*
                   L ++ P+ +++ l +l+l   +++ +dR  F++  ++ +L   
    KIAA0623   296 LMPsiPRETSPYLANLLLGLLQRNQKDRMDFEAFfsHPFL    335  

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