hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080502/iprscan-20080502-00325229/chunk_1/iprscan-20080502-00325229.nocrc
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Query sequence: KIAA0351
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
PF00617.10.fs RasGEF domain                                  189.6    7.1e-54   1
PF00617.10.ls RasGEF domain                                  176.4    6.7e-50   1
PF00169.19.fs PH domain                                       65.7    1.6e-19   1
PF00169.19.ls PH domain                                       67.7    3.4e-17   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PF00617.10.fs   1/1      80   251 ..     1   207 [.   189.6  7.1e-54
PF00617.10.ls   1/1      80   271 ..     1   227 []   176.4  6.7e-50
PF00169.19.fs   1/1     465   576 ..     1    92 []    65.7  1.6e-19
PF00169.19.ls   1/1     465   576 ..     1    92 []    67.7  3.4e-17

Alignments of top-scoring domains:
PF00617.10.fs: domain 1 of 1, from 80 to 251: score 189.6, E = 7.1e-54
                   *->LlldplelAkQLTLlEhelfkkItpfefLgsKmKHEGPqvWgkksfk
                      L + p e+A Q TL++  +fk I p+e+           +W+kk   
    KIAA0351    80    LKVTPEEFASQITLMDIPVFKAIQPEELAS--------CGWSKK--- 115  

                   vkneripnidktiknfNqltnfvsetIlkqeFPTNPEFSKkvdpkkRaev
                   +k  ++pn  +++++fNq++ +v ++Il ++           + k Rae+
    KIAA0351   116 EKHSLAPNVVAFTRRFNQVSFWVVREILTAQ-----------TLKIRAEI 154  

                   iqkfIqVAdhcReLnNFnSllaIisALysspIyRLkkTWekvppqslklI
                   +++f+ +A +++eLnN+ Sl++++sAL+s+pI+RL+kTW++++++++ + 
    KIAA0351   155 LSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTT- 203  

                   feeLnkLmdsdrNfsnyRelLksigplappnLdddfvraPCVPFfGvYLs
                   fe+L  Lm+ + N++++Re ++s   +            P +P++G YL 
    KIAA0351   204 FEKLDYLMSKEDNYKRTREYIRSLKMV------------PSIPYLGIYLL 241  

                   DLtfleeGnp<-*
                   DL  ++++ p   
    KIAA0351   242 DLIYIDSAYP    251  

PF00617.10.ls: domain 1 of 1, from 80 to 271: score 176.4, E = 6.7e-50
                   *->LlldplelAkQLTLlEhelfkkItpfefLgsKmKHEGPqvWgkksfk
                      L + p e+A Q TL++  +fk I p+e+           +W+kk   
    KIAA0351    80    LKVTPEEFASQITLMDIPVFKAIQPEELAS--------CGWSKK--- 115  

                   vkneripnidktiknfNqltnfvsetIlkqeFPTNPEFSKkvdpkkRaev
                   +k  ++pn  +++++fNq++ +v ++Il ++           + k Rae+
    KIAA0351   116 EKHSLAPNVVAFTRRFNQVSFWVVREILTAQ-----------TLKIRAEI 154  

                   iqkfIqVAdhcReLnNFnSllaIisALysspIyRLkkTWekvppqslklI
                   +++f+ +A +++eLnN+ Sl++++sAL+s+pI+RL+kTW++++++++ + 
    KIAA0351   155 LSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTT- 203  

                   feeLnkLmdsdrNfsnyRelLksigplappnLdddfvraPCVPFfGvYLs
                   fe+L  Lm+ + N++++Re ++s   +            P +P++G YL 
    KIAA0351   204 FEKLDYLMSKEDNYKRTREYIRSLKMV------------PSIPYLGIYLL 241  

                   DLtfleeGnp...dyleekKINtnlvNFsKrrk<-*
                   DL  ++++ p ++++ e+     + + ++   +   
    KIAA0351   242 DLIYIDSAYPasgSIMENE---QRSNQMNNILR    271  

PF00169.19.fs: domain 1 of 1, from 465 to 576: score 65.7, E = 1.6e-19
                   *->vikeGwLlkkg........gkkswkkRyfvLfddvLlyykdkk....
                      +++eG L++k+  +++++++++sw +++++L++++Llyy  k+ +++
    KIAA0351   465    PTMEGPLRRKTllkegrkpALSSWTRYWVILSGSTLLYYGAKSlrgt 511  

                   ......kkpkgsipLsgiqvtkvpdnkrkncFeirt.dr.etlllqaese
                   ++++ +++p +++++ g  v  ++d++++ +F++ ++d+++++ +q+ s 
    KIAA0351   512 drkhykSTPGKKVSIVGWMVQLPDDPEHPDIFQLNNpDKgNVYKFQTGSR 561  

                   eerkeWvkaiqsair<-*
                    ++  W k++ +a++   
    KIAA0351   562 FHAILWHKHLDDACK    576  

PF00169.19.ls: domain 1 of 1, from 465 to 576: score 67.7, E = 3.4e-17
                   *->vikeGwLlkkg........gkkswkkRyfvLfddvLlyykdkk....
                      +++eG L++k+  +++++++++sw +++++L++++Llyy  k+ +++
    KIAA0351   465    PTMEGPLRRKTllkegrkpALSSWTRYWVILSGSTLLYYGAKSlrgt 511  

                   ......kkpkgsipLsgiqvtkvpdnkrkncFeirt.dr.etlllqaese
                   ++++ +++p +++++ g  v  ++d++++ +F++ ++d+++++ +q+ s 
    KIAA0351   512 drkhykSTPGKKVSIVGWMVQLPDDPEHPDIFQLNNpDKgNVYKFQTGSR 561  

                   eerkeWvkaiqsair<-*
                    ++  W k++ +a++   
    KIAA0351   562 FHAILWHKHLDDACK    576  

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