Nr search
BLASTX 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= KCC002562A_C01 KCC002562A_c01
(1056 letters)
Database: nr
1,537,769 sequences; 498,525,298 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gb|AAL35383.1|AF442557_1 putative ABC transporter [Chlamydomonas... 718 0.0
ref|NP_610079.2| CG9270-PA [Drosophila melanogaster] gi|22946960... 206 4e-52
gb|AAQ22531.1| LD15381p [Drosophila melanogaster] 206 4e-52
gb|AAL85706.1|AF474335_1 ABC transporter ABCC.3 [Dictyostelium d... 202 1e-50
ref|NP_038818.1| ATP-binding cassette, sub-family C, member 5; A... 200 4e-50
>gb|AAL35383.1|AF442557_1 putative ABC transporter [Chlamydomonas reinhardtii]
Length = 1082
Score = 718 bits (1854), Expect = 0.0
Identities = 350/351 (99%), Positives = 350/351 (99%)
Frame = +3
Query: 3 HVPKFEVKPGQVVAVVGRIAAGKSSLVQAILGNMVKEHGSFNVGGRISYVPQNPWLQNLS 182
HVPKFEVKPGQVVAVVGRIAAGKSSLVQAILGNMVKEHGSFNVGGRISYVPQNPWLQNLS
Sbjct: 192 HVPKFEVKPGQVVAVVGRIAAGKSSLVQAILGNMVKEHGSFNVGGRISYVPQNPWLQNLS 251
Query: 183 LRDNVLFGEQFDENKYTDVIESCALTLDLQILSNGDQSKAGIRGVNFSGGQRQRVNLARC 362
LRDNVLFGEQFDENKYTDVIESCALTLDLQILSNGDQSKAGIRGVNFSGGQRQRVNLARC
Sbjct: 252 LRDNVLFGEQFDENKYTDVIESCALTLDLQILSNGDQSKAGIRGVNFSGGQRQRVNLARC 311
Query: 363 AYADADLVLLDNALSAVDHHTVHHIFDKCIKGLFSDKAVVLVTHQIEFMPRCDNVAIMDE 542
AYADADLVLLDNALSAVDHHT HHIFDKCIKGLFSDKAVVLVTHQIEFMPRCDNVAIMDE
Sbjct: 312 AYADADLVLLDNALSAVDHHTAHHIFDKCIKGLFSDKAVVLVTHQIEFMPRCDNVAIMDE 371
Query: 543 GRCLYFGKWNEEAQHLLGKLLPITHLLHAAGSQEAPPAPKKKAEDKAGPQKSQSLQLTLA 722
GRCLYFGKWNEEAQHLLGKLLPITHLLHAAGSQEAPPAPKKKAEDKAGPQKSQSLQLTLA
Sbjct: 372 GRCLYFGKWNEEAQHLLGKLLPITHLLHAAGSQEAPPAPKKKAEDKAGPQKSQSLQLTLA 431
Query: 723 PTSIGKPTEKPKDVQKLTAYQAALIYTWYGNLFLVGVCFFFFLAAQCSRQISDFWVRWWV 902
PTSIGKPTEKPKDVQKLTAYQAALIYTWYGNLFLVGVCFFFFLAAQCSRQISDFWVRWWV
Sbjct: 432 PTSIGKPTEKPKDVQKLTAYQAALIYTWYGNLFLVGVCFFFFLAAQCSRQISDFWVRWWV 491
Query: 903 NDEYKKFPVKGEQDSAATTFYCLIYLLLVGLFYIFMIFRGATFLWWVLKSS 1055
NDEYKKFPVKGEQDSAATTFYCLIYLLLVGLFYIFMIFRGATFLWWVLKSS
Sbjct: 492 NDEYKKFPVKGEQDSAATTFYCLIYLLLVGLFYIFMIFRGATFLWWVLKSS 542
Score = 75.1 bits (183), Expect = 2e-12
Identities = 64/235 (27%), Positives = 103/235 (43%), Gaps = 14/235 (5%)
Frame = +3
Query: 15 FEVKPGQVVAVVGRIAAGKSSLVQAILGNMVKEHGSFNVGG-------------RISYVP 155
F++ G+ V VGR +GKS+ + A+ G V G +S +P
Sbjct: 841 FKINDGEKVGAVGRTGSGKSTTLLALYRMFELGKGRILVDGVDIATLSLKRLRTGLSIIP 900
Query: 156 QNPWLQNLSLRDNV-LFGEQFDENKYTDVIESCALTLDLQILSNGDQSKAGIRGVNFSGG 332
Q P + ++R N+ FGE D+ +V++ L Q D G G +S G
Sbjct: 901 QEPVMFTGTVRSNLDPFGEFKDDAILWEVLKKVGLEDQAQHAGGLDGQVDGTGGKAWSLG 960
Query: 333 QRQRVNLARCAYADADLVLLDNALSAVDHHTVHHIFDKCIKGLFSDKAVVLVTHQIEFMP 512
Q Q V LAR A ++ LD A +A+D HT I + IK +F D+ + + H+++ +
Sbjct: 961 QMQLVCLARAALRAVPILCLDEATAAMDPHT-EAIVQQTIKKVFDDRTTITIAHRLDTII 1019
Query: 513 RCDNVAIMDEGRCLYFGKWNEEAQHLLGKLLPITHLLHAAGSQEAPPAPKKKAED 677
D + +M++G + + E LL + L A A +K AED
Sbjct: 1020 ESDKIIVMEQGSLMEY----ESPSKLLANRDSMFSKLVDKTGPAAAAALRKMAED 1070
>ref|NP_610079.2| CG9270-PA [Drosophila melanogaster] gi|22946960|gb|AAF53950.2|
CG9270-PA [Drosophila melanogaster]
Length = 1145
Score = 206 bits (525), Expect = 4e-52
Identities = 129/358 (36%), Positives = 187/358 (52%), Gaps = 13/358 (3%)
Frame = +3
Query: 21 VKPGQVVAVVGRIAAGKSSLVQAILGNMVKEHGSFNVGGRISYVPQNPWLQNLSLRDNVL 200
+ P Q+VAV+G + +GKSSL+QAILG + E G V G ISY Q PWL N S+RDN+L
Sbjct: 290 LSPPQLVAVIGPVGSGKSSLIQAILGELPGESGKLKVQGDISYASQEPWLFNASVRDNIL 349
Query: 201 FGEQFDENKYTDVIESCALTLDLQILSNGDQSKAGIRGVNFSGGQRQRVNLARCAYADAD 380
FG D+++Y +VI +CAL D ++L +GD++ G RG + SGGQR R++LAR Y AD
Sbjct: 350 FGLPMDKHRYRNVIRNCALERDFELL-HGDRTFVGERGASLSGGQRARISLARAVYRQAD 408
Query: 381 LVLLDNALSAVDHHTVHHIFDKCIKGLFSDKAVVLVTHQIEFMPRCDNVAIMDEGRCLYF 560
LLD+ LSAVD H H+F++C++G DK V+LVTHQ++F+ D + IMD+G+
Sbjct: 409 TYLLDDPLSAVDTHVGRHLFEECMRGFLRDKLVILVTHQLQFLEHADLIVIMDKGKISAV 468
Query: 561 GKWNE--EAQHLLGKLLPITHLLHAAGSQEAPPAPKKKAEDKAGPQKSQSLQLTLAPTSI 734
G + E ++ GKLL +QE A DK+ + S ++ TS+
Sbjct: 469 GTYEEMLKSGQDFGKLLATEAQEMGDSNQEQVNAEGDSRNDKSTYSRQSSRVSRVSVTSV 528
Query: 735 GKPTEKPKDVQKLTAY----QAALIYTWYGNLFLVG-------VCFFFFLAAQCSRQISD 881
TE D ++ A Q + YG F G + FF L Q D
Sbjct: 529 DSSTESILDNERQPAQESRSQGKIGLGIYGKYFSAGSGWLMVILVAFFCLGTQILASGGD 588
Query: 882 FWVRWWVNDEYKKFPVKGEQDSAATTFYCLIYLLLVGLFYIFMIFRGATFLWWVLKSS 1055
+++ +W VK S++T Y I+ + IF + R F + SS
Sbjct: 589 YFLSYW---------VKNNDSSSSTDIY--IFSGINAALVIFALLRTLLFFSMAMHSS 635
Score = 88.2 bits (217), Expect = 2e-16
Identities = 60/195 (30%), Positives = 101/195 (51%), Gaps = 12/195 (6%)
Frame = +3
Query: 15 FEVKPGQVVAVVGRIAAGKSSLVQAIL------GNMVKEH------GSFNVGGRISYVPQ 158
F + P + + +VGR AGKSSL+ A+ G++V ++ G ++ +IS +PQ
Sbjct: 908 FIIMPREKIGIVGRTGAGKSSLINALFRLSYNEGSLVIDNTDILGIGLHDLRSKISIIPQ 967
Query: 159 NPWLQNLSLRDNVLFGEQFDENKYTDVIESCALTLDLQILSNGDQSKAGIRGVNFSGGQR 338
P L + +LR N+ EQ+ + K + +E L ++ L NG +S G N+S GQR
Sbjct: 968 EPVLFSGTLRCNLDPFEQYADEKLWEALEEVHLKDEVSELPNGLESVVAEGGSNYSVGQR 1027
Query: 339 QRVNLARCAYADADLVLLDNALSAVDHHTVHHIFDKCIKGLFSDKAVVLVTHQIEFMPRC 518
Q V LAR + ++++D A + VD T + I+ F D V+ + H++ +
Sbjct: 1028 QLVCLARAILRENRILVMDEATANVDPQT-DALIQSTIRRKFRDCTVLTIAHRLNTIIDS 1086
Query: 519 DNVAIMDEGRCLYFG 563
D V ++D G + FG
Sbjct: 1087 DRVMVLDAGTLVEFG 1101
>gb|AAQ22531.1| LD15381p [Drosophila melanogaster]
Length = 1145
Score = 206 bits (525), Expect = 4e-52
Identities = 129/358 (36%), Positives = 187/358 (52%), Gaps = 13/358 (3%)
Frame = +3
Query: 21 VKPGQVVAVVGRIAAGKSSLVQAILGNMVKEHGSFNVGGRISYVPQNPWLQNLSLRDNVL 200
+ P Q+VAV+G + +GKSSL+QAILG + E G V G ISY Q PWL N S+RDN+L
Sbjct: 290 LSPPQLVAVIGPVGSGKSSLIQAILGELPGESGKLKVQGDISYASQEPWLFNASVRDNIL 349
Query: 201 FGEQFDENKYTDVIESCALTLDLQILSNGDQSKAGIRGVNFSGGQRQRVNLARCAYADAD 380
FG D+++Y +VI +CAL D ++L +GD++ G RG + SGGQR R++LAR Y AD
Sbjct: 350 FGLPMDKHRYRNVIRNCALERDFELL-HGDRTFVGERGASLSGGQRARISLARAVYRQAD 408
Query: 381 LVLLDNALSAVDHHTVHHIFDKCIKGLFSDKAVVLVTHQIEFMPRCDNVAIMDEGRCLYF 560
LLD+ LSAVD H H+F++C++G DK V+LVTHQ++F+ D + IMD+G+
Sbjct: 409 TYLLDDPLSAVDTHVGRHLFEECMRGFLRDKLVILVTHQLQFLEHADLIVIMDKGKISAV 468
Query: 561 GKWNE--EAQHLLGKLLPITHLLHAAGSQEAPPAPKKKAEDKAGPQKSQSLQLTLAPTSI 734
G + E ++ GKLL +QE A DK+ + S ++ TS+
Sbjct: 469 GTYEEMLKSGQDFGKLLATEAQEMGDSNQEQVNAEGDSRNDKSTYSRQSSRVSRVSVTSV 528
Query: 735 GKPTEKPKDVQKLTAY----QAALIYTWYGNLFLVG-------VCFFFFLAAQCSRQISD 881
TE D ++ A Q + YG F G + FF L Q D
Sbjct: 529 DSSTESILDNERQPAQESRSQGKIGLGIYGKYFSAGSGWLMVILVAFFCLGTQILASGGD 588
Query: 882 FWVRWWVNDEYKKFPVKGEQDSAATTFYCLIYLLLVGLFYIFMIFRGATFLWWVLKSS 1055
+++ +W VK S++T Y I+ + IF + R F + SS
Sbjct: 589 YFLSYW---------VKNNDSSSSTDIY--IFSGINAALVIFALLRTLLFFSMAMHSS 635
Score = 88.2 bits (217), Expect = 2e-16
Identities = 60/195 (30%), Positives = 101/195 (51%), Gaps = 12/195 (6%)
Frame = +3
Query: 15 FEVKPGQVVAVVGRIAAGKSSLVQAIL------GNMVKEH------GSFNVGGRISYVPQ 158
F + P + + +VGR AGKSSL+ A+ G++V ++ G ++ +IS +PQ
Sbjct: 908 FIIMPREKIGIVGRTGAGKSSLINALFRLSYNEGSLVIDNTDILGIGLHDLRSKISIIPQ 967
Query: 159 NPWLQNLSLRDNVLFGEQFDENKYTDVIESCALTLDLQILSNGDQSKAGIRGVNFSGGQR 338
P L + +LR N+ EQ+ + K + +E L ++ L NG +S G N+S GQR
Sbjct: 968 EPVLFSGTLRCNLDPFEQYADEKLWEALEEVHLKDEVSELPNGLESVVAEGGSNYSVGQR 1027
Query: 339 QRVNLARCAYADADLVLLDNALSAVDHHTVHHIFDKCIKGLFSDKAVVLVTHQIEFMPRC 518
Q V LAR + ++++D A + VD T + I+ F D V+ + H++ +
Sbjct: 1028 QLVCLARAILRENRILVMDEATANVDPQT-DALIQSTIRRKFRDCTVLTIAHRLNTIIDS 1086
Query: 519 DNVAIMDEGRCLYFG 563
D V ++D G + FG
Sbjct: 1087 DRVMVLDAGTLVEFG 1101
>gb|AAL85706.1|AF474335_1 ABC transporter ABCC.3 [Dictyostelium discoideum]
Length = 1390
Score = 202 bits (513), Expect = 1e-50
Identities = 128/357 (35%), Positives = 190/357 (52%), Gaps = 15/357 (4%)
Frame = +3
Query: 15 FEVKPGQVVAVVGRIAAGKSSLVQAILGNMVKEHGSFNVGGRISYVPQNPWLQNLSLRDN 194
FE K + +VG + +GKSSL+QA+LG M GS + G ++YVPQ W+ N +L+DN
Sbjct: 440 FEAKGKTLTMIVGSVGSGKSSLIQAMLGEMDVLDGSVAMKGNVAYVPQQAWIINATLKDN 499
Query: 195 VLFGEQFDENKYTDVIESCALTLDLQILSNGDQSKAGIRGVNFSGGQRQRVNLARCAYAD 374
+LFG +DE KY V+E CAL D+++ GD + G RGVN SGGQ+QRV++AR Y+D
Sbjct: 500 ILFGSPYDEAKYRKVLEVCALERDIELFPQGDLVEIGERGVNLSGGQKQRVSIARAVYSD 559
Query: 375 ADLVLLDNALSAVDHHTVHHIFDKCIKGLFSDKAVVLVTHQIEFMPRCDNVAIMDEGRCL 554
+D+ +LD+ LSAVD H H+F +C KG+ K V+L +Q+ ++P N ++ G
Sbjct: 560 SDVYILDDPLSAVDAHVGKHLFHRCFKGILKSKTVILAANQLNYLPFAHNTVVLKAGEIS 619
Query: 555 YFGKWNEEAQHLLGKLLPITHLLHAAGSQEAPPAPKKKAEDKAGPQKSQSLQLTLAPTSI 734
G + Q L+ + LL A G E+ A + ED ++S ++ +
Sbjct: 620 ERGSY----QQLINAQKEFSGLLQAYGVDES--AVNEDVEDDKEIEESDNIVV----EEK 669
Query: 735 GKPTEKPKDVQK---LTAYQ-------AALIYTWY---GNLFLVGVCFFFFLAAQCSRQI 875
KPTEKPK K LT+ + A +Y Y G FL + F FFL +R
Sbjct: 670 TKPTEKPKLQNKDGVLTSQEEREEGAVAMWVYWKYITVGGGFLFLMAFIFFLMDTGTRTF 729
Query: 876 SDFWVRWWVNDEYKK--FPVKGEQDSAATTFYCLIYLLLVGLFYIFMIFRGATFLWW 1040
D+W+ W N+ K +G + S T L + VG+ I +I G FL++
Sbjct: 730 VDWWLSHWQNESTKNALAVAQGLEPSGLTDTQYLGIYIGVGMTSI-LISAGRNFLFF 785
Score = 81.6 bits (200), Expect = 2e-14
Identities = 68/256 (26%), Positives = 122/256 (47%), Gaps = 14/256 (5%)
Frame = +3
Query: 18 EVKPGQVVAVVGRIAAGKSSLVQAILGNMVKEHGSFNVGGR-------------ISYVPQ 158
E+K + + +VGR AGKSS+V A+ + G+ + G ++ +PQ
Sbjct: 1063 EIKAKEKIGIVGRTGAGKSSIVLALFRLIEASEGAILIDGENIAKFGLKDLRRNLAIIPQ 1122
Query: 159 NPWLQNLSLRDNV-LFGEQFDENKYTDVIESCALTLDLQILSNGDQSKAGIRGVNFSGGQ 335
+P L + +LR+N+ F E+ D+ ++ V++ L + L G SK G N+S GQ
Sbjct: 1123 DPVLFSGTLRENIDPFNEKTDDQLWS-VLKDIQLHDVAKSLEGGLDSKVTENGDNWSVGQ 1181
Query: 336 RQRVNLARCAYADADLVLLDNALSAVDHHTVHHIFDKCIKGLFSDKAVVLVTHQIEFMPR 515
RQ + LAR D +++LD A ++VD H+ + I+ FS+ ++ + H++ +
Sbjct: 1182 RQLLCLARALLRDPKILVLDEATASVDGHS-DSLIQATIREKFSNCTILTIAHRLNTIMD 1240
Query: 516 CDNVAIMDEGRCLYFGKWNEEAQHLLGKLLPITHLLHAAGSQEAPPAPKKKAEDKAGPQK 695
D + ++D G+ F + Q+ G L L+ G Q A ++ A+ K
Sbjct: 1241 SDRIIVLDAGKISEFDEPWTLLQNPAGLL---NWLVEETGPQNAAYL-RRLAQAKKDGVN 1296
Query: 696 SQSLQLTLAPTSIGKP 743
+ ++PT KP
Sbjct: 1297 IDQITPPISPTPEQKP 1312
>ref|NP_038818.1| ATP-binding cassette, sub-family C, member 5; ATP-binding cassette,
sub-family C (CFTR/MRP), member 5a; ATP-binding cassette,
sub-family C (CFTR/MRP), member 5b [Mus musculus]
gi|8928229|sp|Q9R1X5|MRP5_MOUSE Multidrug
resistance-associated protein 5 (ABC transporter MOAT-C)
(SMRP) gi|4587085|dbj|BAA76609.1| MRP5 [Mus musculus]
Length = 1436
Score = 200 bits (508), Expect = 4e-50
Identities = 125/366 (34%), Positives = 186/366 (50%), Gaps = 20/366 (5%)
Frame = +3
Query: 18 EVKPGQVVAVVGRIAAGKSSLVQAILGNMVKEHGSFNVGGRISYVPQNPWLQNLSLRDNV 197
E++ G++V + G + +GK+SLV AILG M GS V G +YV Q W+ N +LRDN+
Sbjct: 584 EIEEGKLVGICGSVGSGKTSLVSAILGQMTLLEGSIAVSGTFAYVAQQAWILNATLRDNI 643
Query: 198 LFGEQFDENKYTDVIESCALTLDLQILSNGDQSKAGIRGVNFSGGQRQRVNLARCAYADA 377
LFG++FDE +Y V+ SC L DL IL N D ++ G RG N SGGQRQR++LAR Y+D
Sbjct: 644 LFGKEFDEERYNSVLNSCCLRPDLAILPNSDLTEIGERGANLSGGQRQRISLARALYSDR 703
Query: 378 DLVLLDNALSAVDHHTVHHIFDKCIKGLFSDKAVVLVTHQIEFMPRCDNVAIMDEGRCLY 557
+ +LD+ LSA+D H +HIF+ I+ K V+ VTHQ++++ CD V M EG C+
Sbjct: 704 SIYILDDPLSALDAHVGNHIFNSAIRKRLKSKTVLFVTHQLQYLVDCDEVIFMKEG-CIT 762
Query: 558 FGKWNEEAQHLLGKLLPITHLLHAAGSQEAPPAPKKKAEDKAGPQKSQSLQLTLAPTSIG 737
+EE +L G I + L E PP ++ G QKSQ P S+
Sbjct: 763 ERGTHEELMNLNGDYATIFNNLLLG---ETPPVEINSKKEATGSQKSQ--DKGPKPGSVK 817
Query: 738 K----PTEKPKDVQKLTAYQAALIYTWY-------GNLFLVGVCFFFFLAAQCSRQISDF 884
K +E+ + VQ Q ++ ++ Y G V F+ S S +
Sbjct: 818 KEKAVKSEEGQLVQVEEKGQGSVPWSVYWVYIQAAGGPLAFLVIMVLFMLNVGSTAFSTW 877
Query: 885 WVRWWVN---------DEYKKFPVKGEQDSAATTFYCLIYLLLVGLFYIFMIFRGATFLW 1037
W+ +W+ + F +D+ +Y IY L + + I RG F+
Sbjct: 878 WLSYWIKQGSGNSTVYQGNRSFVSDSMKDNPFMQYYASIYALSMAVMLILKAIRGVVFVK 937
Query: 1038 WVLKSS 1055
L++S
Sbjct: 938 GTLRAS 943
Score = 74.7 bits (182), Expect = 2e-12
Identities = 50/204 (24%), Positives = 100/204 (48%), Gaps = 22/204 (10%)
Frame = +3
Query: 15 FEVKPGQVVAVVGRIAAGKSSLVQAIL-------------GNMVKEHGSFNVGGRISYVP 155
F +KP + + +VGR +GKSSL A+ G + + G ++ +++ +P
Sbjct: 1214 FTIKPKEKIGIVGRTGSGKSSLGMALFRLVELSGGCIKIDGIRISDIGLADLRSKLAIIP 1273
Query: 156 QNPWLQNLSLRDNVLFGEQFDENKYTDVIE---------SCALTLDLQILSNGDQSKAGI 308
Q P L + ++R N+ Q+ E++ D +E L L+ +++ NGD
Sbjct: 1274 QEPVLFSGTVRSNLDPFNQYTEDQIWDALERTHMKECIAQLPLKLESEVMENGD------ 1327
Query: 309 RGVNFSGGQRQRVNLARCAYADADLVLLDNALSAVDHHTVHHIFDKCIKGLFSDKAVVLV 488
NFS G+RQ + +AR +++LD A +A+D T + + I+ F+D ++ +
Sbjct: 1328 ---NFSVGERQLLCIARALLRHCKILILDEATAAMDTET-DLLIQETIREAFADCTMLTI 1383
Query: 489 THQIEFMPRCDNVAIMDEGRCLYF 560
H++ + D + ++ +G+ + F
Sbjct: 1384 AHRLHTVLGSDRIMVLAQGQVVEF 1407
