Nr search
BLASTX 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= KCC002538A_C01 KCC002538A_c01
(589 letters)
Database: nr
1,537,769 sequences; 498,525,298 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|NP_663583.1| cDNA sequence BC021891; mixed lineage kinase 4 ... 95 8e-19
emb|CAC17571.1| dJ862P8.3 (Similar to MAP3K10 (mitogen-activated... 95 8e-19
ref|XP_226572.2| similar to Mixed lineage kinase 4 [Rattus norve... 91 9e-18
emb|CAC84639.1| mixed lineage kinase 4alpha [Homo sapiens] 91 9e-18
ref|NP_115811.1| mixed lineage kinase 4 [Homo sapiens] gi|177367... 91 9e-18
>ref|NP_663583.1| cDNA sequence BC021891; mixed lineage kinase 4 [Mus musculus]
gi|18257338|gb|AAH21891.1| CDNA sequence BC021891 [Mus
musculus]
Length = 1001
Score = 94.7 bits (234), Expect = 8e-19
Identities = 67/199 (33%), Positives = 100/199 (49%), Gaps = 4/199 (2%)
Frame = +2
Query: 2 HPNIVKLLAVCLTPPRFCMVMELMQLNLAQLLHGDIGRVCTCGAQGSGPCSPYCPMSSRA 181
HPNI++L VCL P C+V+E + G + R A S P +P P +R
Sbjct: 166 HPNIIQLRGVCLRQPHLCLVLEFAR-------GGALNRALAAAA--SDPRAP-GPRRARR 215
Query: 182 LPLVMVLDIAIDVARALAYLHP----TVSHRDLKPANVLLTWSESAEALAASARSGGSGS 349
+P ++++ A+ +AR + YLH + HRDLK +N+LL + +
Sbjct: 216 IPPQVLVNWAVQIARGMLYLHEEAVVPILHRDLKSSNILLLEKIEHDDICNK-------- 267
Query: 350 AASGGGRRRRIVAKLSDFGISRMSHTLRATITPEAGTPAYIAPECFNPANWLVSCKSDMY 529
K++DFG++R H R T AGT A++APE + L S SD++
Sbjct: 268 -----------TLKITDFGLAREWH--RTTRMSAAGTYAWMAPEVIRSS--LFSKGSDIW 312
Query: 530 AYGVLLWELLTSLEPWKGI 586
+YGVLLWELLT P++GI
Sbjct: 313 SYGVLLWELLTGEVPYRGI 331
>emb|CAC17571.1| dJ862P8.3 (Similar to MAP3K10 (mitogen-activated protein kinase
kinase kinase 10)) [Homo sapiens]
Length = 564
Score = 94.7 bits (234), Expect = 8e-19
Identities = 65/199 (32%), Positives = 98/199 (48%), Gaps = 4/199 (2%)
Frame = +2
Query: 2 HPNIVKLLAVCLTPPRFCMVMELMQLNLAQLLHGDIGRVCTCGAQGSGPCSPYCPMSSRA 181
HPNI++L VCL P C+V+E + G + R P +P P +R
Sbjct: 180 HPNIIELRGVCLQQPHLCLVLEFAR-------GGALNRALAAANAAPDPRAP-GPRRARR 231
Query: 182 LPLVMVLDIAIDVARALAYLHP----TVSHRDLKPANVLLTWSESAEALAASARSGGSGS 349
+P ++++ A+ +AR + YLH + HRDLK +N+LL + +
Sbjct: 232 IPPHVLVNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEKIEHDDICNK-------- 283
Query: 350 AASGGGRRRRIVAKLSDFGISRMSHTLRATITPEAGTPAYIAPECFNPANWLVSCKSDMY 529
K++DFG++R H R T AGT A++APE + L S SD++
Sbjct: 284 -----------TLKITDFGLAREWH--RTTKMSTAGTYAWMAPEVIKSS--LFSKGSDIW 328
Query: 530 AYGVLLWELLTSLEPWKGI 586
+YGVLLWELLT P++GI
Sbjct: 329 SYGVLLWELLTGEVPYRGI 347
>ref|XP_226572.2| similar to Mixed lineage kinase 4 [Rattus norvegicus]
Length = 995
Score = 91.3 bits (225), Expect = 9e-18
Identities = 66/199 (33%), Positives = 98/199 (49%), Gaps = 4/199 (2%)
Frame = +2
Query: 2 HPNIVKLLAVCLTPPRFCMVMELMQLNLAQLLHGDIGRVCTCGAQGSGPCSPYCPMSSRA 181
HPNI++L VCL P C+V+E + G + R A P P P +R
Sbjct: 166 HPNIIQLRGVCLQQPHLCLVLEFAR-------GGALNRALAAAAPD--PRVPG-PRRARR 215
Query: 182 LPLVMVLDIAIDVARALAYLHPT----VSHRDLKPANVLLTWSESAEALAASARSGGSGS 349
+P ++++ A+ +AR + YLH + HRDLK +N+LL + +
Sbjct: 216 IPPHVLVNWAVQIARGMLYLHEEAVVPILHRDLKSSNILLLEKIEHDDICNKT------- 268
Query: 350 AASGGGRRRRIVAKLSDFGISRMSHTLRATITPEAGTPAYIAPECFNPANWLVSCKSDMY 529
K++DFG++R H R T AGT A++APE + L S SD++
Sbjct: 269 ------------LKITDFGLAREWH--RTTRMSAAGTYAWMAPEVIRSS--LFSKGSDIW 312
Query: 530 AYGVLLWELLTSLEPWKGI 586
+YGVLLWELLT P++GI
Sbjct: 313 SYGVLLWELLTGEVPYRGI 331
>emb|CAC84639.1| mixed lineage kinase 4alpha [Homo sapiens]
Length = 570
Score = 91.3 bits (225), Expect = 9e-18
Identities = 64/199 (32%), Positives = 97/199 (48%), Gaps = 4/199 (2%)
Frame = +2
Query: 2 HPNIVKLLAVCLTPPRFCMVMELMQLNLAQLLHGDIGRVCTCGAQGSGPCSPYCPMSSRA 181
HPNI++L VCL P C+V+E + G + R P +P P +R
Sbjct: 180 HPNIIELRGVCLQQPHLCLVLEFAR-------GGALNRALAAANAAPDPRAP-GPRRARR 231
Query: 182 LPLVMVLDIAIDVARALAYLHP----TVSHRDLKPANVLLTWSESAEALAASARSGGSGS 349
+P ++++ A+ +AR + YLH + HRDLK +N+LL + +
Sbjct: 232 IPPHVLVNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEEIEHDDICNK-------- 283
Query: 350 AASGGGRRRRIVAKLSDFGISRMSHTLRATITPEAGTPAYIAPECFNPANWLVSCKSDMY 529
K++DFG++R H R T AGT A++APE + L S SD++
Sbjct: 284 -----------TLKITDFGLAREWH--RTTKMSTAGTYAWMAPEVIKSS--LFSKGSDIW 328
Query: 530 AYGVLLWELLTSLEPWKGI 586
+ GVLLWELLT P++GI
Sbjct: 329 SCGVLLWELLTGEVPYRGI 347
>ref|NP_115811.1| mixed lineage kinase 4 [Homo sapiens] gi|17736731|emb|CAC84640.1|
mixed lineage kinase 4beta [Homo sapiens]
Length = 1036
Score = 91.3 bits (225), Expect = 9e-18
Identities = 64/199 (32%), Positives = 97/199 (48%), Gaps = 4/199 (2%)
Frame = +2
Query: 2 HPNIVKLLAVCLTPPRFCMVMELMQLNLAQLLHGDIGRVCTCGAQGSGPCSPYCPMSSRA 181
HPNI++L VCL P C+V+E + G + R P +P P +R
Sbjct: 180 HPNIIELRGVCLQQPHLCLVLEFAR-------GGALNRALAAANAAPDPRAP-GPRRARR 231
Query: 182 LPLVMVLDIAIDVARALAYLHP----TVSHRDLKPANVLLTWSESAEALAASARSGGSGS 349
+P ++++ A+ +AR + YLH + HRDLK +N+LL + +
Sbjct: 232 IPPHVLVNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEEIEHDDICNK-------- 283
Query: 350 AASGGGRRRRIVAKLSDFGISRMSHTLRATITPEAGTPAYIAPECFNPANWLVSCKSDMY 529
K++DFG++R H R T AGT A++APE + L S SD++
Sbjct: 284 -----------TLKITDFGLAREWH--RTTKMSTAGTYAWMAPEVIKSS--LFSKGSDIW 328
Query: 530 AYGVLLWELLTSLEPWKGI 586
+ GVLLWELLT P++GI
Sbjct: 329 SCGVLLWELLTGEVPYRGI 347
