Nr search
BLASTX 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= KCC001185A_C01 KCC001185A_c01
(662 letters)
Database: nr
1,537,769 sequences; 498,525,298 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gb|AAA36487.1| profilaggrin 44 0.002
gb|AAA63244.1| profilaggrin 44 0.002
pir||A35938 profilaggrin - human (fragments) 43 0.004
ref|XP_048104.2| similar to profilaggrin - human (fragments) [Ho... 42 0.011
gb|AAA63246.1| profilaggrin 41 0.014
>gb|AAA36487.1| profilaggrin
Length = 1218
Score = 44.3 bits (103), Expect = 0.002
Identities = 31/134 (23%), Positives = 52/134 (38%), Gaps = 9/134 (6%)
Frame = -3
Query: 510 SARSAVLKLGHVHDAVEGLGHVDGQKAGDDKQAHHGATARSQRASGR---------HPQA 358
S+R + + G AV GH + + Q H + SQ S + H ++
Sbjct: 1042 SSRHSAIGRGQASSAVRDRGHRGSRGSQASDQEGHSEDSDSQSVSAQRQAGSHQQSHQES 1101
Query: 357 VRSGDEGQGGDEPVVAVQLLARKNRGETIDAGQGASGLRYGTHSESSRSAPKSDYGAGDD 178
R +G+ G Q+ + + ++G R G+H E +R + +
Sbjct: 1102 TRGRSQGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQ 1161
Query: 177 ETQRPHARSGRGGR 136
+T R H S RGGR
Sbjct: 1162 DTIRAHPGSRRGGR 1175
Score = 40.4 bits (93), Expect = 0.024
Identities = 33/136 (24%), Positives = 52/136 (37%), Gaps = 11/136 (8%)
Frame = -3
Query: 510 SARSAVLKLGHVHDAVEGLGH--VDGQKAGDDKQAHHGATARSQRASGR---------HP 364
S+R + + G AV GH G +A D Q H + SQ SG+ H
Sbjct: 718 SSRHSGIGHGQASSAVRDSGHRGYSGSQASD--QEGHSENSDSQSVSGQRQARSHQQSHQ 775
Query: 363 QAVRSGDEGQGGDEPVVAVQLLARKNRGETIDAGQGASGLRYGTHSESSRSAPKSDYGAG 184
++ R G+ G Q+ + ++ R G+H + +R + +
Sbjct: 776 ESTRGQSRGRSGRSGSFLYQVSTHEQSESAHGRSAPSTRRRQGSHHDQARDSSRHSASQE 835
Query: 183 DDETQRPHARSGRGGR 136
+T R H S RGGR
Sbjct: 836 GQDTIRGHPGSSRGGR 851
Score = 34.7 bits (78), Expect = 1.3
Identities = 30/117 (25%), Positives = 43/117 (36%), Gaps = 9/117 (7%)
Frame = -3
Query: 462 EGLGHVDGQKAGDDKQAHHGATARSQRASGRHPQAVRSGDEGQGGDEPVVAVQLLARKNR 283
EG + +G + HHG+ R RHP RS DE + +
Sbjct: 304 EGHSEDSERHSGSASRNHHGSAWEQSRDGSRHP---RSHDEDRASHGHSADSSRQSGTRH 360
Query: 282 GETIDAGQGAS---------GLRYGTHSESSRSAPKSDYGAGDDETQRPHARSGRGG 139
ET GQ AS G R+G+H + S + + G G + + SG G
Sbjct: 361 AETSSRGQTASSHEQARSSAGERHGSHHQQSADSSRHS-GIGHGQASTAVSDSGHRG 416
Score = 32.3 bits (72), Expect = 6.5
Identities = 33/139 (23%), Positives = 47/139 (33%), Gaps = 19/139 (13%)
Frame = -3
Query: 453 GHVDGQKAGDDKQAHHGATARSQRASGRHPQAVRSGDEGQGGDEPVVAVQLLARKNRGET 274
GH ++ HH + +A+ QA S E G Q A +R
Sbjct: 669 GHRQSAESSSQSGTHHAENSSGGQAASSQEQARSSAGERHGSGH-----QQSADSSRHSG 723
Query: 273 IDAGQGASGLRYGTHSESSRSAPKSDYGAGDDETQ---------RPHARS---------- 151
I GQ +S +R H S S G ++ R H +S
Sbjct: 724 IGHGQASSAVRDSGHRGYSGSQASDQEGHSENSDSQSVSGQRQARSHQQSHQESTRGQSR 783
Query: 150 GRGGRPCFFIEKLKVMEQS 94
GR GR F+ ++ EQS
Sbjct: 784 GRSGRSGSFLYQVSTHEQS 802
Score = 32.0 bits (71), Expect = 8.5
Identities = 38/133 (28%), Positives = 50/133 (37%), Gaps = 11/133 (8%)
Frame = -3
Query: 432 AGDDKQAHHGATARSQRASG-RHPQAVR----SGDEGQGGDEPVVAVQLLARKNRGETID 268
AG+ +HH +A S R SG H QA SG G G + A N G + D
Sbjct: 380 AGERHGSHHQQSADSSRHSGIGHGQASTAVSDSGHRGYRGSQ--------ASDNEGHSED 431
Query: 267 ------AGQGASGLRYGTHSESSRSAPKSDYGAGDDETQRPHARSGRGGRPCFFIEKLKV 106
AGQ + R+ +H ES+R R SGR G + + +
Sbjct: 432 SDSQSVAGQRQARSRHQSHQESTRG--------------RSRGGSGRSGSFLYQVSTHEQ 477
Query: 105 MEQSHDILTGFTG 67
E SH TG
Sbjct: 478 SESSHGWARTSTG 490
>gb|AAA63244.1| profilaggrin
Length = 990
Score = 44.3 bits (103), Expect = 0.002
Identities = 31/134 (23%), Positives = 52/134 (38%), Gaps = 9/134 (6%)
Frame = -3
Query: 510 SARSAVLKLGHVHDAVEGLGHVDGQKAGDDKQAHHGATARSQRASGR---------HPQA 358
S+R + + G AV GH + + Q H + SQ S + H ++
Sbjct: 820 SSRHSAIGRGQASSAVRDRGHRGSRGSQASDQEGHSEDSDSQSVSAQRQAGSHQQSHQES 879
Query: 357 VRSGDEGQGGDEPVVAVQLLARKNRGETIDAGQGASGLRYGTHSESSRSAPKSDYGAGDD 178
R +G+ G Q+ + + ++G R G+H E +R + +
Sbjct: 880 TRGRSQGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQ 939
Query: 177 ETQRPHARSGRGGR 136
+T R H S RGGR
Sbjct: 940 DTIRAHPGSRRGGR 953
Score = 40.4 bits (93), Expect = 0.024
Identities = 33/136 (24%), Positives = 52/136 (37%), Gaps = 11/136 (8%)
Frame = -3
Query: 510 SARSAVLKLGHVHDAVEGLGH--VDGQKAGDDKQAHHGATARSQRASGR---------HP 364
S+R + + G AV GH G +A D Q H + SQ SG+ H
Sbjct: 496 SSRHSGIGHGQASSAVRDSGHRGYSGSQASD--QEGHSENSDSQSVSGQRQARSHQQSHQ 553
Query: 363 QAVRSGDEGQGGDEPVVAVQLLARKNRGETIDAGQGASGLRYGTHSESSRSAPKSDYGAG 184
++ R G+ G Q+ + ++ R G+H + +R + +
Sbjct: 554 ESTRGQSRGRSGRSGSFLYQVSTHEQSESAHGRSAPSTRRRQGSHHDQARDSSRHSASQE 613
Query: 183 DDETQRPHARSGRGGR 136
+T R H S RGGR
Sbjct: 614 GQDTIRGHPGSSRGGR 629
Score = 33.9 bits (76), Expect = 2.2
Identities = 30/116 (25%), Positives = 44/116 (37%), Gaps = 11/116 (9%)
Frame = -3
Query: 453 GHVDGQK--AGDDKQAHHGATARSQRASGRHPQAVRSGDEGQGGDEPVVAVQLLARKNRG 280
GH + + +G + HHG+ R RHP RS DE + +
Sbjct: 83 GHSEDSERHSGSASRNHHGSAWEQSRDGSRHP---RSHDEDRASHGHSADSSRQSGTRHA 139
Query: 279 ETIDAGQGAS---------GLRYGTHSESSRSAPKSDYGAGDDETQRPHARSGRGG 139
ET GQ AS G R+G+H + S + + G G + + SG G
Sbjct: 140 ETSSRGQTASSHEQARSSAGERHGSHHQQSADSSRHS-GIGHGQASTAVSDSGHRG 194
Score = 32.3 bits (72), Expect = 6.5
Identities = 33/139 (23%), Positives = 47/139 (33%), Gaps = 19/139 (13%)
Frame = -3
Query: 453 GHVDGQKAGDDKQAHHGATARSQRASGRHPQAVRSGDEGQGGDEPVVAVQLLARKNRGET 274
GH ++ HH + +A+ QA S E G Q A +R
Sbjct: 447 GHRQSAESSSQSGTHHAENSSGGQAASSQEQARSSAGERHGSGH-----QQSADSSRHSG 501
Query: 273 IDAGQGASGLRYGTHSESSRSAPKSDYGAGDDETQ---------RPHARS---------- 151
I GQ +S +R H S S G ++ R H +S
Sbjct: 502 IGHGQASSAVRDSGHRGYSGSQASDQEGHSENSDSQSVSGQRQARSHQQSHQESTRGQSR 561
Query: 150 GRGGRPCFFIEKLKVMEQS 94
GR GR F+ ++ EQS
Sbjct: 562 GRSGRSGSFLYQVSTHEQS 580
Score = 32.0 bits (71), Expect = 8.5
Identities = 38/133 (28%), Positives = 50/133 (37%), Gaps = 11/133 (8%)
Frame = -3
Query: 432 AGDDKQAHHGATARSQRASG-RHPQAVR----SGDEGQGGDEPVVAVQLLARKNRGETID 268
AG+ +HH +A S R SG H QA SG G G + A N G + D
Sbjct: 158 AGERHGSHHQQSADSSRHSGIGHGQASTAVSDSGHRGYRGSQ--------ASDNEGHSED 209
Query: 267 ------AGQGASGLRYGTHSESSRSAPKSDYGAGDDETQRPHARSGRGGRPCFFIEKLKV 106
AGQ + R+ +H ES+R R SGR G + + +
Sbjct: 210 SDSQSVAGQRQARSRHQSHQESTRG--------------RSRGGSGRSGSFLYQVSTHEQ 255
Query: 105 MEQSHDILTGFTG 67
E SH TG
Sbjct: 256 SESSHGWARTSTG 268
>pir||A35938 profilaggrin - human (fragments)
Length = 2248
Score = 43.1 bits (100), Expect = 0.004
Identities = 31/134 (23%), Positives = 52/134 (38%), Gaps = 9/134 (6%)
Frame = -3
Query: 510 SARSAVLKLGHVHDAVEGLGHVDGQKAGDDKQAHHGATARSQRASGR---------HPQA 358
S+R + + G AV GH + + Q H + SQ S + H ++
Sbjct: 820 SSRHSGIGRGQASSAVRDRGHRGSRGSQASDQEGHSEDSDSQSVSAQRQAGSHQQSHQES 879
Query: 357 VRSGDEGQGGDEPVVAVQLLARKNRGETIDAGQGASGLRYGTHSESSRSAPKSDYGAGDD 178
R +G+ G Q+ + + ++G R G+H E +R + +
Sbjct: 880 TRGRSQGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQ 939
Query: 177 ETQRPHARSGRGGR 136
+T R H S RGGR
Sbjct: 940 DTIRAHPGSRRGGR 953
Score = 42.7 bits (99), Expect = 0.005
Identities = 36/134 (26%), Positives = 57/134 (41%), Gaps = 9/134 (6%)
Frame = -3
Query: 510 SARSAVLKLGHVHDAVEGLGH--VDGQKAGDDKQAHHGATARSQRASGR---HPQAVRSG 346
S+R A + G AV GH G +A D + + +S A G+ H QA +
Sbjct: 1499 SSRHAGIGHGQASSAVRDSGHRGYRGSQATDSEGHSEDSDTQSVSAQGQAGPHQQAHQES 1558
Query: 345 DEGQGGDEPVVAVQLLARKNRGETIDAGQGAS----GLRYGTHSESSRSAPKSDYGAGDD 178
GQ G+ + L + + E ++ G S G R G+H + ++ + +
Sbjct: 1559 ARGQSGESSGRSGSFLYQVSTHEQSESTHGQSVPSTGGRQGSHHDQAQDSSRHSASQEGQ 1618
Query: 177 ETQRPHARSGRGGR 136
+T R H S RGGR
Sbjct: 1619 DTIRGHPGSSRGGR 1632
Score = 40.8 bits (94), Expect = 0.018
Identities = 37/139 (26%), Positives = 50/139 (35%), Gaps = 19/139 (13%)
Frame = -3
Query: 453 GHVDGQKAGDDKQAHHGATARSQRASGRHPQAVRSGDEGQGGDEPVVAVQLLARKNRGET 274
GH ++ D HH + +A+ H QA S E G Q A +R
Sbjct: 1774 GHRHSAESSDQSGTHHAENSSGGQAASSHEQARSSAGERHGSHH-----QQSADSSRHSG 1828
Query: 273 IDAGQGASGLRYGTHSESSRSAPKSDYGAGDDET-------------QRPHARSGRG--- 142
I GQ +S +R H SS S G +D Q+ H S RG
Sbjct: 1829 IGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGSHQQSHQESTRGRSQ 1888
Query: 141 ---GRPCFFIEKLKVMEQS 94
GR F+ ++ EQS
Sbjct: 1889 EGSGRSGSFLYQVSTHEQS 1907
Score = 40.4 bits (93), Expect = 0.024
Identities = 33/136 (24%), Positives = 52/136 (37%), Gaps = 11/136 (8%)
Frame = -3
Query: 510 SARSAVLKLGHVHDAVEGLGH--VDGQKAGDDKQAHHGATARSQRASGR---------HP 364
S+R + + G AV GH G +A D Q H + SQ SG+ H
Sbjct: 496 SSRHSGIGHGQASSAVRDSGHRGYSGSQASD--QEGHSENSDSQSVSGQRQARSHQQSHQ 553
Query: 363 QAVRSGDEGQGGDEPVVAVQLLARKNRGETIDAGQGASGLRYGTHSESSRSAPKSDYGAG 184
++ R G+ G Q+ + ++ R G+H + +R + +
Sbjct: 554 ESTRGQSRGRSGRSGSFLYQVSTHEQSESAHGRSAPSTRRRQGSHHDQARDSSRHSASQE 613
Query: 183 DDETQRPHARSGRGGR 136
+T R H S RGGR
Sbjct: 614 GQDTIRGHPGSSRGGR 629
Score = 35.0 bits (79), Expect = 1.0
Identities = 29/134 (21%), Positives = 50/134 (36%), Gaps = 9/134 (6%)
Frame = -3
Query: 510 SARSAVLKLGHVHDAVEGLGH--VDGQKAGDDKQAHHGATARSQRASGR-------HPQA 358
S+R + + G AV GH G +A D + + +S A G+ H ++
Sbjct: 1000 SSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAQGQAGPHQQSHQES 1059
Query: 357 VRSGDEGQGGDEPVVAVQLLARKNRGETIDAGQGASGLRYGTHSESSRSAPKSDYGAGDD 178
R G+ G Q+ + + ++ R G+H E +R + +
Sbjct: 1060 TRGRSAGRSGRSGSFLYQVSTHEQSESAHGRARTSTRGRQGSHHEQARDSSRHSTSQEGQ 1119
Query: 177 ETQRPHARSGRGGR 136
+T R H GGR
Sbjct: 1120 DTIRGHPGPSSGGR 1133
Score = 34.3 bits (77), Expect = 1.7
Identities = 47/164 (28%), Positives = 63/164 (37%), Gaps = 35/164 (21%)
Frame = -3
Query: 480 HVHDAVEGLGHVDGQKAGDDKQAHHGATARSQRASGRHPQAV-RSGDEG--------QGG 328
H A + H Q+ D +AH G+ R R H Q+V RSG G QG
Sbjct: 922 HHEQARDSSRHSASQEGQDTIRAHPGSR-RGGRQGSHHEQSVDRSGHSGSHHSHTTSQGR 980
Query: 327 DEPVVAV-------QLLARKNRGETIDAGQGASGLRYGTHSESSRS-APKSDYGAGDDET 172
+ Q A +R I GQ +S +R H SS S A S+ + D +T
Sbjct: 981 SDASHGQSGSGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDT 1040
Query: 171 QR--------PHARS----------GRGGRPCFFIEKLKVMEQS 94
Q PH +S GR GR F+ ++ EQS
Sbjct: 1041 QSVSAQGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQS 1084
Score = 33.9 bits (76), Expect = 2.2
Identities = 30/116 (25%), Positives = 44/116 (37%), Gaps = 11/116 (9%)
Frame = -3
Query: 453 GHVDGQK--AGDDKQAHHGATARSQRASGRHPQAVRSGDEGQGGDEPVVAVQLLARKNRG 280
GH + + +G + HHG+ R RHP RS DE + +
Sbjct: 83 GHSEDSERHSGSASRNHHGSAWEQSRDGSRHP---RSHDEDRASHGHSADSSRQSGTRHA 139
Query: 279 ETIDAGQGAS---------GLRYGTHSESSRSAPKSDYGAGDDETQRPHARSGRGG 139
ET GQ AS G R+G+H + S + + G G + + SG G
Sbjct: 140 ETSSRGQTASSHEQARSSAGERHGSHHQQSADSSRHS-GIGHGQASTAVSDSGHRG 194
Score = 32.3 bits (72), Expect = 6.5
Identities = 33/139 (23%), Positives = 47/139 (33%), Gaps = 19/139 (13%)
Frame = -3
Query: 453 GHVDGQKAGDDKQAHHGATARSQRASGRHPQAVRSGDEGQGGDEPVVAVQLLARKNRGET 274
GH ++ HH + +A+ QA S E G Q A +R
Sbjct: 447 GHRQSAESSSQSGTHHAENSSGGQAASSQEQARSSAGERHGSGH-----QQSADSSRHSG 501
Query: 273 IDAGQGASGLRYGTHSESSRSAPKSDYGAGDDETQ---------RPHARS---------- 151
I GQ +S +R H S S G ++ R H +S
Sbjct: 502 IGHGQASSAVRDSGHRGYSGSQASDQEGHSENSDSQSVSGQRQARSHQQSHQESTRGQSR 561
Query: 150 GRGGRPCFFIEKLKVMEQS 94
GR GR F+ ++ EQS
Sbjct: 562 GRSGRSGSFLYQVSTHEQS 580
Score = 32.0 bits (71), Expect = 8.5
Identities = 38/133 (28%), Positives = 50/133 (37%), Gaps = 11/133 (8%)
Frame = -3
Query: 432 AGDDKQAHHGATARSQRASG-RHPQAVR----SGDEGQGGDEPVVAVQLLARKNRGETID 268
AG+ +HH +A S R SG H QA SG G G + A N G + D
Sbjct: 158 AGERHGSHHQQSADSSRHSGIGHGQASTAVSDSGHRGYRGSQ--------ASDNEGHSED 209
Query: 267 ------AGQGASGLRYGTHSESSRSAPKSDYGAGDDETQRPHARSGRGGRPCFFIEKLKV 106
AGQ + R+ +H ES+R R SGR G + + +
Sbjct: 210 SDSQSVAGQRQARSRHQSHQESTRG--------------RSRGGSGRSGSFLYQVSTHEQ 255
Query: 105 MEQSHDILTGFTG 67
E SH TG
Sbjct: 256 SESSHGWARTSTG 268
Score = 32.0 bits (71), Expect = 8.5
Identities = 34/118 (28%), Positives = 48/118 (39%), Gaps = 2/118 (1%)
Frame = -3
Query: 483 GHVHDAVEGLGHVDGQKAGDDKQAHHGAT-ARSQRASGRHPQAVRSGDEGQGGDEPVVAV 307
GH D+ GQ AG +Q+H +T RSQ SG RSG +
Sbjct: 1856 GHSEDSDTQSVSAHGQ-AGSHQQSHQESTRGRSQEGSG------RSGS----------FL 1898
Query: 306 QLLARKNRGETIDAGQGAS-GLRYGTHSESSRSAPKSDYGAGDDETQRPHARSGRGGR 136
++ + E+ G S G R G+ E +R + + +T R H S RGGR
Sbjct: 1899 YQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGR 1956
>ref|XP_048104.2| similar to profilaggrin - human (fragments) [Homo sapiens]
Length = 5689
Score = 41.6 bits (96), Expect = 0.011
Identities = 32/131 (24%), Positives = 51/131 (38%), Gaps = 2/131 (1%)
Frame = -3
Query: 522 VRERSARSAVLKLGHVHDAVEGLGHVDGQKAGDDKQA--HHGATARSQRASGRHPQAVRS 349
+ R A SAV GH + +G D Q+ HG Q++ H ++ R
Sbjct: 2677 IPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQS---HQESARD 2733
Query: 348 GDEGQGGDEPVVAVQLLARKNRGETIDAGQGASGLRYGTHSESSRSAPKSDYGAGDDETQ 169
G+ G Q+ + + ++G R G+H E +R + + +T
Sbjct: 2734 WSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTI 2793
Query: 168 RPHARSGRGGR 136
R H S RGGR
Sbjct: 2794 RAHPGSRRGGR 2804
Score = 40.4 bits (93), Expect = 0.024
Identities = 33/134 (24%), Positives = 56/134 (41%), Gaps = 9/134 (6%)
Frame = -3
Query: 510 SARSAVLKLGHVHDAVEGLGH--VDGQKAGDDKQAHHGATARSQRASGR---HPQAVRSG 346
S+R + + G AV GH G +A D + + +S A G+ H Q+ +
Sbjct: 3644 SSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKES 3703
Query: 345 DEGQGGDEPVVAVQLLARKNRGETIDAGQGAS----GLRYGTHSESSRSAPKSDYGAGDD 178
GQ G+ + L + + E ++ G S G R G+H + ++ + +
Sbjct: 3704 ARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQ 3763
Query: 177 ETQRPHARSGRGGR 136
+T R H RGGR
Sbjct: 3764 DTIRGHPGPSRGGR 3777
Score = 40.4 bits (93), Expect = 0.024
Identities = 33/134 (24%), Positives = 54/134 (39%), Gaps = 9/134 (6%)
Frame = -3
Query: 510 SARSAVLKLGHVHDAVEGLGH--VDGQKAGDDKQAHHGATARSQRASGR---HPQAVRSG 346
S+R + G AV GH G +A D + + +S G+ Q+ +
Sbjct: 2103 SSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQES 2162
Query: 345 DEGQGGDEPVVAVQLLARKNRGETIDAGQGASGL----RYGTHSESSRSAPKSDYGAGDD 178
G+ G+ + L + + E D+ G +G R G+H E +R + +
Sbjct: 2163 TRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQ 2222
Query: 177 ETQRPHARSGRGGR 136
+T R H S RGGR
Sbjct: 2223 DTIRGHPGSSRGGR 2236
Score = 40.0 bits (92), Expect = 0.031
Identities = 39/139 (28%), Positives = 54/139 (38%), Gaps = 19/139 (13%)
Frame = -3
Query: 453 GHVDGQKAGDDKQAHHGATARSQRASGRHPQAVRSGDEGQGGDEPVVAVQLLARKNRGET 274
GH ++ HH + +A+ H QA S E G Q A +R
Sbjct: 5215 GHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHH-----QQSADSSRHSG 5269
Query: 273 IDAGQGASGLRYGTHSESSRS-APKSDYGAGDDETQR--------PHARS---------- 151
I GQ +S +R H SS S A S+ + D +TQ PH +S
Sbjct: 5270 IGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSA 5329
Query: 150 GRGGRPCFFIEKLKVMEQS 94
GR GR F+ ++ EQS
Sbjct: 5330 GRSGRSGSFLYQVSTHEQS 5348
Score = 38.9 bits (89), Expect = 0.069
Identities = 30/109 (27%), Positives = 44/109 (39%), Gaps = 2/109 (1%)
Frame = -3
Query: 462 EGLGHVDGQKAGDDKQAHHGATARSQRASGRHPQAVRSGDEGQGGDEPVVAVQLLARKNR 283
EG + +G + HHG+ R RHP RS DE + +
Sbjct: 2013 EGHSEDSERHSGSASRNHHGSAWEQSRDGSRHP---RSHDEDRASHGHSADSSRQSGTRH 2069
Query: 282 GETIDAGQGASGLRYGTHSESSRSAPKSDYGAGDDET--QRPHARSGRG 142
ET GQ AS E +RS+P +G+G ++ H+ +GRG
Sbjct: 2070 AETSSRGQTASS------HEQARSSPGERHGSGHQQSADSSRHSATGRG 2112
Score = 35.4 bits (80), Expect = 0.77
Identities = 29/117 (24%), Positives = 43/117 (35%), Gaps = 9/117 (7%)
Frame = -3
Query: 462 EGLGHVDGQKAGDDKQAHHGATARSQRASGRHPQAVRSGDEGQGGDEPVVAVQLLARKNR 283
EG +++G + HHG+ R RHP RS E + G + +
Sbjct: 3878 EGHSEDSERRSGSASRNHHGSAQEQSRDGSRHP---RSHHEDRAGHGHSAESSRQSGTHH 3934
Query: 282 GETIDAGQGAS---------GLRYGTHSESSRSAPKSDYGAGDDETQRPHARSGRGG 139
E GQ AS G R+G+H + S + + G G + SG G
Sbjct: 3935 AENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHS-GIGHGQASSAVRDSGHRG 3990
Score = 35.0 bits (79), Expect = 1.0
Identities = 31/142 (21%), Positives = 53/142 (36%), Gaps = 9/142 (6%)
Frame = -3
Query: 510 SARSAVLKLGHVHDAVEGLGH--VDGQKAGDDKQAHHGATARSQRASGR-------HPQA 358
S+R + + G AV GH G +A D + + +S A G+ H ++
Sbjct: 3968 SSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQES 4027
Query: 357 VRSGDEGQGGDEPVVAVQLLARKNRGETIDAGQGASGLRYGTHSESSRSAPKSDYGAGDD 178
R G+ G Q+ + ++G R G+H + +R + +
Sbjct: 4028 TRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQ 4087
Query: 177 ETQRPHARSGRGGRPCFFIEKL 112
+T H S GGR E+L
Sbjct: 4088 DTIHGHPGSSSGGRQGSHYEQL 4109
Score = 32.3 bits (72), Expect = 6.5
Identities = 29/116 (25%), Positives = 43/116 (37%), Gaps = 11/116 (9%)
Frame = -3
Query: 453 GHVDGQK--AGDDKQAHHGATARSQRASGRHPQAVRSGDEGQGGDEPVVAVQLLARKNRG 280
GH + + +G + HHG+ R RHP RS E + G +
Sbjct: 4203 GHSEDSERWSGSASRNHHGSAQEQLRDGSRHP---RSHQEDRAGHGHSADSSRQSGTRHT 4259
Query: 279 ETIDAGQGAS---------GLRYGTHSESSRSAPKSDYGAGDDETQRPHARSGRGG 139
+T GQ AS G R+G+H + S + + G G + SG G
Sbjct: 4260 QTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHS-GIGHGQASSAVRDSGHRG 4314
Score = 32.3 bits (72), Expect = 6.5
Identities = 29/116 (25%), Positives = 43/116 (37%), Gaps = 11/116 (9%)
Frame = -3
Query: 453 GHVDGQK--AGDDKQAHHGATARSQRASGRHPQAVRSGDEGQGGDEPVVAVQLLARKNRG 280
GH + + +G + HHG+ R RHP RS E + G +
Sbjct: 4527 GHSEDSERWSGSASRNHHGSAQEQLRDGSRHP---RSHQEDRAGHGHSADSSRQSGTRHT 4583
Query: 279 ETIDAGQGAS---------GLRYGTHSESSRSAPKSDYGAGDDETQRPHARSGRGG 139
+T GQ AS G R+G+H + S + + G G + SG G
Sbjct: 4584 QTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHS-GIGHGQASSAVRDSGHRG 4638
>gb|AAA63246.1| profilaggrin
Length = 465
Score = 41.2 bits (95), Expect = 0.014
Identities = 35/136 (25%), Positives = 55/136 (39%), Gaps = 11/136 (8%)
Frame = -3
Query: 510 SARSAVLKLGHVHDAVEGLGH--VDGQKAGDDKQAHHGATARSQRASGR-----HPQAVR 352
S+R + G AV GH G +A D + H + +Q SG Q+ +
Sbjct: 172 SSRHSATGRGQASSAVSDRGHRGSSGSQASDSEG--HSENSDTQSVSGHGQARLRQQSHQ 229
Query: 351 SGDEGQGGDEPVVAVQLLARKNRGETIDAGQGASGL----RYGTHSESSRSAPKSDYGAG 184
G+ G+ + L + + E D+ G +G R G+H E +R + +
Sbjct: 230 ESARGRSGERSGRSGSFLYQVSTHEQSDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQE 289
Query: 183 DDETQRPHARSGRGGR 136
+T R H S RGGR
Sbjct: 290 GQDTIRGHPGSSRGGR 305
Score = 38.1 bits (87), Expect = 0.12
Identities = 30/109 (27%), Positives = 44/109 (39%), Gaps = 2/109 (1%)
Frame = -3
Query: 462 EGLGHVDGQKAGDDKQAHHGATARSQRASGRHPQAVRSGDEGQGGDEPVVAVQLLARKNR 283
EG + +G + HHG+ R RHP RS DE + +
Sbjct: 82 EGHSEDSERHSGSASRNHHGSAWEQSRDVSRHP---RSHDEDRASHGHSADSSRQSGTRH 138
Query: 282 GETIDAGQGASGLRYGTHSESSRSAPKSDYGAGDDET--QRPHARSGRG 142
ET GQ AS E +RS+P +G+G ++ H+ +GRG
Sbjct: 139 AETSSRGQTASS------HEQARSSPGERHGSGHQQSADSSRHSATGRG 181
