Nr search
BLASTX 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= KCC000887A_C01 KCC000887A_c01
(671 letters)
Database: nr
1,537,769 sequences; 498,525,298 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|NP_014328.1| Dihydrolipoamide acetyltransferase component (E... 130 2e-29
ref|NP_609118.1| CG5261-PB [Drosophila melanogaster] gi|7297250|... 129 4e-29
ref|XP_343390.1| dihydrolipoamide acetyltransferase [Rattus norv... 125 6e-28
gb|AAH26680.1| Dihydrolipoamide S-acetyltransferase (E2 componen... 124 2e-27
ref|NP_663589.2| dihydrolipoamide S-acetyltransferase (E2 compon... 124 2e-27
>ref|NP_014328.1| Dihydrolipoamide acetyltransferase component (E2) of pyruvate
dehydrogenase complex; Lat1p [Saccharomyces cerevisiae]
gi|129060|sp|P12695|ODP2_YEAST Dihydrolipoamide
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor (E2) (PDC-E2)
gi|82982|pir||A30198 dihydrolipoamide
S-acetyltransferase (EC 2.3.1.12) precursor - yeast
(Saccharomyces cerevisiae) gi|170972|gb|AAA34385.1|
dihydrolipoamide acetyltransferase precursor (EC
2.3.1.12) gi|791115|emb|CAA60189.1| dihydrolipoamide
S-acetyltransferase [Saccharomyces cerevisiae]
gi|1301955|emb|CAA95945.1| LAT1 [Saccharomyces
cerevisiae]
Length = 482
Score = 130 bits (327), Expect = 2e-29
Identities = 64/150 (42%), Positives = 93/150 (61%), Gaps = 10/150 (6%)
Frame = +2
Query: 137 QLQRHGAAAQSCGVLSRCFSGVPAHTIVGMPALSPTMSQGNIAKWHVKPGQEVSPGSVLA 316
++ R +S + RC++ P HTI+GMPALSPTM+QGN+A W K G ++SPG V+A
Sbjct: 10 RISRSSVLTRSLRLQLRCYASYPEHTIIGMPALSPTMTQGNLAAWTKKEGDQLSPGEVIA 69
Query: 317 DIETDKATLAFENQDEGFVAKLLVPDGARDIPIGQPVLVLVEDASSVAAFANF------- 475
+IETDKA + FE Q++G++AK+LVP+G +DIP+ +P+ V VED + V AF +F
Sbjct: 70 EIETDKAQMDFEFQEDGYLAKILVPEGTKDIPVNKPIAVYVEDKADVPAFKDFKLEDSGS 129
Query: 476 ---TPGQSAPADAAPAAPVEQPPAATAAPA 556
T ++ PA+ E P T A
Sbjct: 130 DSKTSTKAQPAEPQAEKKQEAPAEETKTSA 159
>ref|NP_609118.1| CG5261-PB [Drosophila melanogaster] gi|7297250|gb|AAF52514.1|
CG5261-PB [Drosophila melanogaster]
Length = 512
Score = 129 bits (324), Expect = 4e-29
Identities = 65/145 (44%), Positives = 90/145 (61%), Gaps = 1/145 (0%)
Frame = +2
Query: 182 SRCFSGVPAHTIVGMPALSPTMSQGNIAKWHVKPGQEVSPGSVLADIETDKATLAFENQD 361
+R ++ +P H V +PALSPTM +G+I W K G +++ G +L +IETDKAT+ FE +
Sbjct: 71 ARAYANLPEHIRVPLPALSPTMERGSIVSWEKKEGDKLNEGDLLCEIETDKATMGFETPE 130
Query: 362 EGFVAKLLVPDGARDIPIGQPVLVLVEDASSVAAFANFTPGQSAPADAAPAA-PVEQPPA 538
EGF+AK+L+ G +D+P+GQ + ++V D SVAAFANF +A A AAPAA P P A
Sbjct: 131 EGFLAKILIQGGTKDVPVGQLLCIIVPDQGSVAAFANFKDDGAAAAPAAPAAAPAPAPAA 190
Query: 539 ATAAPALMEHAYPPHTRLTMPVPVS 613
A A P A P P P +
Sbjct: 191 AAAPPPPPPPAAAPAAAAPPPAPAA 215
>ref|XP_343390.1| dihydrolipoamide acetyltransferase [Rattus norvegicus]
Length = 632
Score = 125 bits (314), Expect = 6e-28
Identities = 62/154 (40%), Positives = 93/154 (60%), Gaps = 2/154 (1%)
Frame = +2
Query: 146 RHGAAAQSCGVLSRCFSGVPAHTIVGMPALSPTMSQGNIAKWHVKPGQEVSPGSVLADIE 325
R+ Q G SR +P H V +P+LSPTM G IA+W K G+++S G ++A++E
Sbjct: 61 RNRILQQLLGSPSRRSYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGEKISEGDLIAEVE 120
Query: 326 TDKATLAFENQDEGFVAKLLVPDGARDIPIGQPVLVLVEDASSVAAFANFTPGQSAPADA 505
TDKAT+ FE+ +E ++AK+LVP+G RD+P+G + + VE + AF N+T + A
Sbjct: 121 TDKATVGFESLEECYMAKILVPEGTRDVPVGSIICITVEKPQDIEAFKNYTLDSATAATQ 180
Query: 506 APAAPVEQPPAATAAPALME--HAYPPHTRLTMP 601
A AP P AA AAP+ +YP H ++ +P
Sbjct: 181 AAPAPAAAPAAAPAAPSASAPGSSYPVHMQIVLP 214
Score = 123 bits (309), Expect = 2e-27
Identities = 60/141 (42%), Positives = 88/141 (61%)
Frame = +2
Query: 155 AAAQSCGVLSRCFSGVPAHTIVGMPALSPTMSQGNIAKWHVKPGQEVSPGSVLADIETDK 334
AAA + S S P H + +PALSPTM+ G + +W K G+++S G +LA+IETDK
Sbjct: 190 AAAPAAPSASAPGSSYPVHMQIVLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDK 249
Query: 335 ATLAFENQDEGFVAKLLVPDGARDIPIGQPVLVLVEDASSVAAFANFTPGQSAPADAAPA 514
AT+ FE Q+EG++AK+LVP+G RD+P+G P+ ++VE +AAFA++ P + P
Sbjct: 250 ATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKQEDIAAFADYRP--TEVTSLKPQ 307
Query: 515 APVEQPPAATAAPALMEHAYP 577
AP PP A P + + P
Sbjct: 308 APPPVPPPVAAVPPIPQPLAP 328
>gb|AAH26680.1| Dihydrolipoamide S-acetyltransferase (E2 component of pyruvate
dehydrogenase complex) [Mus musculus]
Length = 642
Score = 124 bits (310), Expect = 2e-27
Identities = 62/135 (45%), Positives = 88/135 (64%), Gaps = 2/135 (1%)
Frame = +2
Query: 155 AAAQSCGVLSRCFSGVPAHTIVGMPALSPTMSQGNIAKWHVKPGQEVSPGSVLADIETDK 334
AAA + S S P H + +PALSPTM+ G + +W K G+++S G +LA+IETDK
Sbjct: 199 AAAPAAPSASAPGSSYPTHMQIVLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDK 258
Query: 335 ATLAFENQDEGFVAKLLVPDGARDIPIGQPVLVLVEDASSVAAFANFTPGQ--SAPADAA 508
AT+ FE Q+EG++AK+LVP+G RD+P+G P+ ++VE +AAFA++ P + S AA
Sbjct: 259 ATIGFEVQEEGYLAKILVPEGTRDVPLGAPLCIIVEKQEDIAAFADYRPTEVTSLKPQAA 318
Query: 509 PAAPVEQPPAATAAP 553
P AP PP A P
Sbjct: 319 PPAP---PPVAAVPP 330
Score = 122 bits (307), Expect = 4e-27
Identities = 66/163 (40%), Positives = 98/163 (59%), Gaps = 4/163 (2%)
Frame = +2
Query: 125 SAKSQLQRHGAAAQSCGVLSRCFSGVPAHTIVGMPALSPTMSQGNIAKWHVKPGQEVSPG 304
S + R+ Q G SR +P H V +P+LSPTM G IA+W K G+++S G
Sbjct: 62 SGSGTVPRNRLLRQLLGSPSRRSYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGEKISEG 121
Query: 305 SVLADIETDKATLAFENQDEGFVAKLLVPDGARDIPIGQPVLVLVEDASSVAAFANFTPG 484
++A++ETDKAT+ FE+ +E ++AK+LVP+G RD+P+G + + VE + AF N+T
Sbjct: 122 DLIAEVETDKATVGFESLEECYMAKILVPEGTRDVPVGSIICITVEKPQDIEAFKNYTLD 181
Query: 485 QSAPA--DAAPAAPVEQPPAATAAPALME--HAYPPHTRLTMP 601
+A A AAPAA P AA AAP+ +YP H ++ +P
Sbjct: 182 LAAAAAPQAAPAA-APAPAAAPAAPSASAPGSSYPTHMQIVLP 223
>ref|NP_663589.2| dihydrolipoamide S-acetyltransferase (E2 component of pyruvate
dehydrogenase complex); dihydrolipoamide
S-acetyltransferase precursor [Mus musculus]
gi|26327949|dbj|BAC27715.1| unnamed protein product [Mus
musculus]
Length = 642
Score = 124 bits (310), Expect = 2e-27
Identities = 62/135 (45%), Positives = 88/135 (64%), Gaps = 2/135 (1%)
Frame = +2
Query: 155 AAAQSCGVLSRCFSGVPAHTIVGMPALSPTMSQGNIAKWHVKPGQEVSPGSVLADIETDK 334
AAA + S S P H + +PALSPTM+ G + +W K G+++S G +LA+IETDK
Sbjct: 199 AAAPAAPSASAPGSSYPTHMQIVLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDK 258
Query: 335 ATLAFENQDEGFVAKLLVPDGARDIPIGQPVLVLVEDASSVAAFANFTPGQ--SAPADAA 508
AT+ FE Q+EG++AK+LVP+G RD+P+G P+ ++VE +AAFA++ P + S AA
Sbjct: 259 ATIGFEVQEEGYLAKILVPEGTRDVPLGAPLCIIVEKQEDIAAFADYRPTEVTSLKPQAA 318
Query: 509 PAAPVEQPPAATAAP 553
P AP PP A P
Sbjct: 319 PPAP---PPVAAVPP 330
Score = 121 bits (304), Expect = 8e-27
Identities = 64/164 (39%), Positives = 94/164 (57%), Gaps = 5/164 (3%)
Frame = +2
Query: 125 SAKSQLQRHGAAAQSCGVLSRCFSGVPAHTIVGMPALSPTMSQGNIAKWHVKPGQEVSPG 304
S + R+ Q G SR +P H V +P+LSPTM G IA+W K G+++S G
Sbjct: 62 SGSGTVPRNRLLRQLLGSPSRRSYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGEKISEG 121
Query: 305 SVLADIETDKATLAFENQDEGFVAKLLVPDGARDIPIGQPVLVLVEDASSVAAFANFTPG 484
++A++ETDKAT+ FE+ +E ++AK+LVP+G RD+P+G + + VE + AF N+T
Sbjct: 122 DLIAEVETDKATVGFESLEECYMAKILVPEGTRDVPVGSIICITVEKPQDIEAFKNYT-- 179
Query: 485 QSAPADAAPAAPVEQPPAATAAPALME-----HAYPPHTRLTMP 601
A AAP A PA AAPA +YP H ++ +P
Sbjct: 180 LDLAAAAAPQAAPAAAPATAAAPAAPSASAPGSSYPTHMQIVLP 223
