Nr search
BLASTX 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= KCC000387A_C01 KCC000387A_c01
(1982 letters)
Database: nr
1,537,769 sequences; 498,525,298 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gb|AAM74046.1|AF481771_1 cAMP-dependent protein kinase regulator... 136 1e-30
gb|AAG30146.1|AF288614_1 cAMP dependent protein kinase regulator... 132 2e-29
gb|AAA33015.1| cAMP-dependent protein kinase regulatory subunit 126 2e-27
sp|P31320|KAPR_BLAEM cAMP-dependent protein kinase regulatory ch... 125 3e-27
ref|NP_500142.1| EGg Laying defective EGL-4, ODoRant response ab... 125 4e-27
>gb|AAM74046.1|AF481771_1 cAMP-dependent protein kinase regulatory subunit [Cryptococcus
neoformans var. neoformans]
Length = 482
Score = 136 bits (343), Expect = 1e-30
Identities = 87/309 (28%), Positives = 157/309 (50%), Gaps = 6/309 (1%)
Frame = +3
Query: 528 RKLAVGGPQAKEEKEKIYEVSDSEDEELEDDPSERTTLSGD--WYKPQEVTDAILEALKR 701
R+ +V ++ Y + + +E+D + SG + K +E I +A+K
Sbjct: 157 RRTSVSAESLVPTSQRAYGPTSGLETTMEEDENTHNLSSGTPVFPKSEEQLARIRQAIKP 216
Query: 702 NFVFKGIPQNHLVEVVGRMYGISFKSGAVVLQQGALPKQDDCMYYLQQGEAEVVISGGAD 881
NF+F+ + +V+ M + +G VV++QGA D Y ++ G +V ++
Sbjct: 217 NFLFRNLDDEQEADVLAAMKEVKMDAGEVVIEQGAA---GDFFYIVENGRLDVFVNKEGQ 273
Query: 882 ASKNHGEERKVDGHTVRIPQKPGWLFGDVALLFHSPRTASVVAKTNITVWAMDRRTFLKF 1061
+R+ G V + G FG++AL+ ++PR AS+++ T T+WA+DR +F
Sbjct: 274 VLDLEKGDRQGLGKKVAECSE-GSSFGELALMHNAPRAASIISLTPCTLWALDRVSFRTI 332
Query: 1062 VMKHAQGARAL--RFLRKLPLLKGLSDNDLIRAASRMPQRMYEDGQPLIRIGERGDELFL 1235
++ H R L FL ++P+L L + + A + R Y +G+ +IR G+ GDE FL
Sbjct: 333 LLDHTSRKRRLYESFLSEVPILASLQPQERAKIADVLESRTYNEGEDVIRQGDAGDEFFL 392
Query: 1236 IRYGKVRVFRPDGNGGRVEVAVLGRGQFVGERAVINDKLRSADCVAQG--QVQVVVLKKR 1409
I G + D +G + V LG+G++ GE A++N + R+A A+G +++V L ++
Sbjct: 393 IESGNAMAIKTDEDGNQSVVKHLGQGEYFGELALLNRRTRAATIRAEGPDKLRVAALGEQ 452
Query: 1410 EFMDLDNPL 1436
F L P+
Sbjct: 453 AFTRLLGPV 461
>gb|AAG30146.1|AF288614_1 cAMP dependent protein kinase regulatory subunit [Cryptococcus
neoformans var. grubii]
Length = 482
Score = 132 bits (333), Expect = 2e-29
Identities = 87/309 (28%), Positives = 156/309 (50%), Gaps = 6/309 (1%)
Frame = +3
Query: 528 RKLAVGGPQAKEEKEKIYEVSDSEDEELEDDPSERTTLSGD--WYKPQEVTDAILEALKR 701
R+ +V ++ Y + + +E+D + SG + K +E I +A+K
Sbjct: 157 RRTSVSAESLVPTSQRGYGPTSGLETTMEEDENTVNLNSGTPVFPKSEEQLARIRQAIKP 216
Query: 702 NFVFKGIPQNHLVEVVGRMYGISFKSGAVVLQQGALPKQDDCMYYLQQGEAEVVISGGAD 881
NF+F+ + +V+ M + +G VV++QGA D Y ++ G +V ++
Sbjct: 217 NFLFRNLDDEQEADVLAAMKEVKVDAGEVVIEQGAA---GDFFYIVENGRLDVFVNKEGQ 273
Query: 882 ASKNHGEERKVDGHTVRIPQKPGWLFGDVALLFHSPRTASVVAKTNITVWAMDRRTFLKF 1061
+R+ G V + G FG++AL+ ++PR AS+++ T T+WA+DR +F
Sbjct: 274 VLDLEKGDRQGLGKKVAECSE-GSSFGELALMHNAPRAASIISLTPCTLWALDRVSFRTI 332
Query: 1062 VMKHAQGARAL--RFLRKLPLLKGLSDNDLIRAASRMPQRMYEDGQPLIRIGERGDELFL 1235
++ H R L FL ++P+L L + + A + R Y +G+ +IR G+ GDE FL
Sbjct: 333 LLDHTSRKRRLYESFLSEVPILASLQPQERAKIADVLESRTYNEGEDVIRQGDAGDEFFL 392
Query: 1236 IRYGKVRVFRPDGNGGRVEVAVLGRGQFVGERAVINDKLRSADCVAQG--QVQVVVLKKR 1409
I G + D +G V LG+G++ GE A++N + R+A A+G +++V L ++
Sbjct: 393 IESGNAMAIKTDEDGNASVVKHLGQGEYFGELALLNRRTRAATIRAEGPDKLRVAALGEQ 452
Query: 1410 EFMDLDNPL 1436
F L P+
Sbjct: 453 AFTRLLGPV 461
>gb|AAA33015.1| cAMP-dependent protein kinase regulatory subunit
Length = 403
Score = 126 bits (316), Expect = 2e-27
Identities = 105/398 (26%), Positives = 177/398 (44%), Gaps = 37/398 (9%)
Frame = +3
Query: 354 TKPSEVPHVEK--AQSINRGQPGD--------GSGPLQQPSPAMPGAKQGGTKERRAAAG 503
T PSE+P + K ++ + R QP D + L Q + + TK A+
Sbjct: 5 TIPSELPPILKDLSREVLRHQPADLVQFCHDYFAKLLAQQRKVLMDSADPATKATIASTA 64
Query: 504 SEAVRDQIRKLAVGGPQAKEEKEKIYEVSDSEDEELEDDPS----------ERTTLSGDW 653
AV + A A + D +D++ EDD + RT++S +
Sbjct: 65 GPAV--DADEAARANSYAYSTDDGFGTEDDDDDDDDEDDEAAIPPPVVNRGRRTSVSAES 122
Query: 654 YKP---------------QEVTDAILEALKRNFVFKGIPQNHLVEVVGRMYGISFKSGAV 788
P E I ++ NF+F+ + ++ +VV M +G V
Sbjct: 123 MAPTAHDVDAVKTVIPKSDEQRARIQASIGNNFLFRNLDEDQYTDVVNAMAEKKVAAGEV 182
Query: 789 VLQQGALPKQDDCMYYLQQGEAEVVISGGADASKNHGEERKVDGHTVRIPQKPGWLFGDV 968
V++QG + D Y ++ G +V ++ +N + KV ++ G FG++
Sbjct: 183 VIRQGGV---GDYFYVVETGALDVFVN------RNGNGDVKVTDYSA------GGSFGEL 227
Query: 969 ALLFHSPRTASVVAKTNITVWAMDRRTFLKFVMKHAQGARAL--RFLRKLPLLKGLSDND 1142
AL++++PR A+VVA +WA+DR TF + +M H R + FL ++PLL L +
Sbjct: 228 ALMYNAPRAATVVATAESVLWALDRVTFRRILMDHTSRKRRMYEAFLEEVPLLSSLEPYE 287
Query: 1143 LIRAASRMPQRMYEDGQPLIRIGERGDELFLIRYGKVRVFRPDGNGGRVEVAVLGRGQFV 1322
+ A + Y DG +IR G+ G+ ++I G V + D NG L +G +
Sbjct: 288 RHKIADALESVAYADGDVVIRQGDVGENFYIIEAGDAEVIKIDENGEEHHFRPLHKGNYF 347
Query: 1323 GERAVINDKLRSADCVAQGQVQVVVLKKREFMDLDNPL 1436
GE A+++DK R A A+G+++ L K+ F L PL
Sbjct: 348 GELALLSDKPRVATIRAKGKLKCATLGKKAFTRLLGPL 385
Score = 67.4 bits (163), Expect = 9e-10
Identities = 56/238 (23%), Positives = 104/238 (43%), Gaps = 5/238 (2%)
Frame = +3
Query: 1116 LLKGLSDNDLIRAASRMPQRMYEDGQPLIRIGERGDELFLIRYGKVRVFRPDGNGGRVEV 1295
L + L ++ + M ++ G+ +IR G GD +++ G + VF G V+V
Sbjct: 156 LFRNLDEDQYTDVVNAMAEKKVAAGEVVIRQGGVGDYFYVVETGALDVFVNRNGNGDVKV 215
Query: 1296 AVLGRGQFVGERAVINDKLRSADCVAQGQVQVVVLKKREFMDLDNPLLAWMLDYDA---- 1463
G GE A++ + R+A VA + + L + F + ++D+ +
Sbjct: 216 TDYSAGGSFGELALMYNAPRAATVVATAESVLWALDRVTFRRI-------LMDHTSRKRR 268
Query: 1464 -VSAVIRSLPQFKGLKQEQMENILDRFDAREELMQGDTILNQGDMLEKLYVVKIGEIALF 1640
A + +P L+ + I D ++ GD ++ QGD+ E Y+++ G+ +
Sbjct: 269 MYEAFLEEVPLLSSLEPYERHKIADALES-VAYADGDVVIRQGDVGENFYIIEAGDAEVI 327
Query: 1641 RNDERVEDPNFVHEIAGFSYFGETAITQTGKCPYTIRVASESLHLLSLPKRQVDSFMG 1814
+ DE E+ +F + +YFGE A+ TIR A L +L K+ +G
Sbjct: 328 KIDENGEEHHF-RPLHKGNYFGELALLSDKPRVATIR-AKGKLKCATLGKKAFTRLLG 383
>sp|P31320|KAPR_BLAEM cAMP-dependent protein kinase regulatory chain gi|285215|pir||A43435
protein kinase (EC 2.7.1.37), cAMP-dependent, type II
regulatory chain - fungus (Blastocladiella emersonii)
gi|167192|gb|AAA33016.1| cAMP-dependent protein kinase
regulatory subunit
Length = 403
Score = 125 bits (314), Expect = 3e-27
Identities = 105/398 (26%), Positives = 177/398 (44%), Gaps = 37/398 (9%)
Frame = +3
Query: 354 TKPSEVPHVEK--AQSINRGQPGD--------GSGPLQQPSPAMPGAKQGGTKERRAAAG 503
T PSE+P + K ++ + R QP D + L Q + + TK A+
Sbjct: 5 TIPSELPPILKDLSREVLRHQPADLVQFCHDYFAKLLAQQRKVLMDSADPATKATIASTA 64
Query: 504 SEAVRDQIRKLAVGGPQAKEEKEKIYEVSDSEDEELEDDPS----------ERTTLSGDW 653
AV + A A + D +D++ EDD + RT++S +
Sbjct: 65 GPAV--DADEAARANSYAYSTDDGFGTEDDDDDDDDEDDEAAIPPPVVNRGRRTSVSAES 122
Query: 654 YKP---------------QEVTDAILEALKRNFVFKGIPQNHLVEVVGRMYGISFKSGAV 788
P E I ++ NF+F+ + ++ +VV M +G V
Sbjct: 123 MAPTAHDVDAVKTVIPKSDEQRARIQASIGNNFLFRNLDEDQYTDVVNAMAEKKVAAGEV 182
Query: 789 VLQQGALPKQDDCMYYLQQGEAEVVISGGADASKNHGEERKVDGHTVRIPQKPGWLFGDV 968
V++QG + D Y ++ G +V ++ +N + KV ++ G FG++
Sbjct: 183 VIRQGGV---GDYFYVVETGALDVFVN------RNGNGDVKVTDYSA------GGSFGEL 227
Query: 969 ALLFHSPRTASVVAKTNITVWAMDRRTFLKFVMKHAQGARAL--RFLRKLPLLKGLSDND 1142
AL++++PR A+VVA +WA+DR TF + +M H R + FL ++PLL L +
Sbjct: 228 ALMYNAPRAATVVATAESVLWALDRVTFRRILMDHTSRKRRMYEAFLEEVPLLSSLEPYE 287
Query: 1143 LIRAASRMPQRMYEDGQPLIRIGERGDELFLIRYGKVRVFRPDGNGGRVEVAVLGRGQFV 1322
+ A + Y DG +IR G+ G+ ++I G V + D NG L +G +
Sbjct: 288 RHKIADALESVAYADGDVVIRQGDVGENFYIIEAGDAEVIKIDENGEEHHFRPLHKGNYF 347
Query: 1323 GERAVINDKLRSADCVAQGQVQVVVLKKREFMDLDNPL 1436
GE A+++DK R A A+G+++ L K+ F L PL
Sbjct: 348 GELALLSDKPRVATIRAKGKLKCAKLGKKAFTRLLGPL 385
Score = 67.0 bits (162), Expect = 1e-09
Identities = 56/238 (23%), Positives = 103/238 (42%), Gaps = 5/238 (2%)
Frame = +3
Query: 1116 LLKGLSDNDLIRAASRMPQRMYEDGQPLIRIGERGDELFLIRYGKVRVFRPDGNGGRVEV 1295
L + L ++ + M ++ G+ +IR G GD +++ G + VF G V+V
Sbjct: 156 LFRNLDEDQYTDVVNAMAEKKVAAGEVVIRQGGVGDYFYVVETGALDVFVNRNGNGDVKV 215
Query: 1296 AVLGRGQFVGERAVINDKLRSADCVAQGQVQVVVLKKREFMDLDNPLLAWMLDYDA---- 1463
G GE A++ + R+A VA + + L + F + ++D+ +
Sbjct: 216 TDYSAGGSFGELALMYNAPRAATVVATAESVLWALDRVTFRRI-------LMDHTSRKRR 268
Query: 1464 -VSAVIRSLPQFKGLKQEQMENILDRFDAREELMQGDTILNQGDMLEKLYVVKIGEIALF 1640
A + +P L+ + I D ++ GD ++ QGD+ E Y+++ G+ +
Sbjct: 269 MYEAFLEEVPLLSSLEPYERHKIADALES-VAYADGDVVIRQGDVGENFYIIEAGDAEVI 327
Query: 1641 RNDERVEDPNFVHEIAGFSYFGETAITQTGKCPYTIRVASESLHLLSLPKRQVDSFMG 1814
+ DE E+ +F + +YFGE A+ TIR A L L K+ +G
Sbjct: 328 KIDENGEEHHF-RPLHKGNYFGELALLSDKPRVATIR-AKGKLKCAKLGKKAFTRLLG 383
>ref|NP_500142.1| EGg Laying defective EGL-4, ODoRant response abnormal ODR-9, Cyclic
GMP-dependent Kinase (egl-4) [Caenorhabditis elegans]
gi|4982489|gb|AAD36953.1|AF067612_2 Egg laying defective
protein 4, isoform b [Caenorhabditis elegans]
Length = 737
Score = 125 bits (313), Expect = 4e-27
Identities = 105/421 (24%), Positives = 205/421 (47%), Gaps = 7/421 (1%)
Frame = +3
Query: 249 ARQQPQATQQKSVEPAVVKKPVEPARVEPKVEVPSTKPSEVPHVEKAQSINRGQPGDGSG 428
+R+ Q QQ+++ +K+ E +E +V + ++ V + ++ + PG
Sbjct: 34 SRKDAQLRQQQTIVEGHIKRISE---LEGEVTTLQRECDKLRSVLEQKAQSAASPGG--- 87
Query: 429 PLQQPSPAMPGAKQGGTKERRAAAGSEAVRDQIRKLAVGGPQAKEEKEKIYEVSDSEDEE 608
Q PSP+ + G +++A ++ V+ + +K+AV +E
Sbjct: 88 --QPPSPSPRTDQLGNDLQQKAVLPADGVQ-RAKKIAVS----------------AEPTN 128
Query: 609 LEDDPSERTTLSGDWYKPQEVTDAILEALKRNFVFKGIPQNHLVEVVGRMYGISFKSGAV 788
E+ P+ TL + K I +A+++N K + + ++E+V MY + ++G
Sbjct: 129 FENKPA---TLQ-HYNKTVGAKQMIRDAVQKNDFLKQLAKEQIIELVNCMYEMRARAGQW 184
Query: 789 VLQQGALPKQDDCMYYLQQGEAEVVISGGADASKNHGEERKVDGHTVRIPQKPGWLFGDV 968
V+Q+G + D ++ + +GE +V G + G + G++
Sbjct: 185 VIQEG---EPGDRLFVVAEGELQVSREGALLGK-----------------MRAGTVMGEL 224
Query: 969 ALLFHSPRTASVVAKTNITVWAMDRRTFLKFVMK--HAQGARALRFLRKLPLLKGLSDND 1142
A+L++ RTASV A T++ +W +DR F + + ++ + FL K+ + + LS++
Sbjct: 225 AILYNCTRTASVQALTDVQLWVLDRSVFQMITQRLGMERHSQLMNFLTKVSIFQNLSEDR 284
Query: 1143 LIRAASRMPQRMYEDGQPLIRIGERGDELFLIRYGKVRVFRP-DGNGGRVEVAVLGRGQF 1319
+ + A M Q Y+ G +IR GE+GD F+I G+V+V + +G E+ VL +G F
Sbjct: 285 ISKMADVMDQDYYDGGHYIIRQGEKGDAFFVINSGQVKVTQQIEGETEPREIRVLNQGDF 344
Query: 1320 VGERAVINDKLRSADCVAQGQ-VQVVVLKKREFMDLDNPLLAWMLDY---DAVSAVIRSL 1487
GERA++ +++R+A+ +AQ V+V+ L + F L L + DY + ++ V+R
Sbjct: 345 FGERALLGEEVRTANIIAQAPGVEVLTLDRESFGKLIGDLESLKKDYGDKERLAQVVREP 404
Query: 1488 P 1490
P
Sbjct: 405 P 405
Score = 66.2 bits (160), Expect = 2e-09
Identities = 58/249 (23%), Positives = 114/249 (45%), Gaps = 3/249 (1%)
Frame = +3
Query: 1101 LRKLPLLKGLSDNDLIRAASRMPQRMYEDGQPLIRIGERGDELFLIRYGKVRVFRPDGNG 1280
++K LK L+ +I + M + GQ +I+ GE GD LF++ G+++V R
Sbjct: 153 VQKNDFLKQLAKEQIIELVNCMYEMRARAGQWVIQEGEPGDRLFVVAEGELQVSR----- 207
Query: 1281 GRVEVAVLGR---GQFVGERAVINDKLRSADCVAQGQVQVVVLKKREFMDLDNPLLAWML 1451
E A+LG+ G +GE A++ + R+A A VQ+ VL + F + L M
Sbjct: 208 ---EGALLGKMRAGTVMGELAILYNCTRTASVQALTDVQLWVLDRSVFQMITQRL--GME 262
Query: 1452 DYDAVSAVIRSLPQFKGLKQEQMENILDRFDAREELMQGDTILNQGDMLEKLYVVKIGEI 1631
+ + + + F+ L ++++ + D D ++ G I+ QG+ + +V+ G++
Sbjct: 263 RHSQLMNFLTKVSIFQNLSEDRISKMADVMD-QDYYDGGHYIIRQGEKGDAFFVINSGQV 321
Query: 1632 ALFRNDERVEDPNFVHEIAGFSYFGETAITQTGKCPYTIRVASESLHLLSLPKRQVDSFM 1811
+ + E +P + + +FGE A+ I + + +L+L + +
Sbjct: 322 KVTQQIEGETEPREIRVLNQGDFFGERALLGEEVRTANIIAQAPGVEVLTLDRESFGKLI 381
Query: 1812 GRDTGLKNE 1838
G LK +
Sbjct: 382 GDLESLKKD 390
