BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC148398.1 + phase: 2 /pseudo/partial
(2332 letters)
Database: uniref100
2,790,947 sequences; 848,049,833 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef100_Q9ZW94 F5A8.4 protein [Arabidopsis thaliana] 698 0.0
UniRef100_Q869L3 Similar to midasin, a large protein with an N-t... 317 3e-84
UniRef100_UPI00002366BE UPI00002366BE UniRef100 entry 303 5e-80
UniRef100_Q6FIU8 Similar to sp|Q12019 Saccharomyces cerevisiae Y... 297 3e-78
UniRef100_Q5RII8 Novel protein similar to human MDN1, midasin ho... 294 3e-77
UniRef100_Q12019 Midasin [Saccharomyces cerevisiae] 290 3e-76
UniRef100_UPI000034DD79 UPI000034DD79 UniRef100 entry 290 5e-76
UniRef100_Q6CJB6 Similar to sp|Q12019 Saccharomyces cerevisiae Y... 286 5e-75
UniRef100_Q6CFC5 Similar to sp|Q12019 Saccharomyces cerevisiae M... 282 8e-74
UniRef100_O94248 SPCC737.08 protein [Schizosaccharomyces pombe] 281 2e-73
UniRef100_UPI000023F705 UPI000023F705 UniRef100 entry 280 3e-73
UniRef100_Q7RYV1 Hypothetical protein [Neurospora crassa] 280 5e-73
UniRef100_Q74ZY4 AGR074Cp [Ashbya gossypii] 279 8e-73
UniRef100_UPI000043035A UPI000043035A UniRef100 entry 272 1e-70
UniRef100_Q9NU22 Midasin [Homo sapiens] 271 2e-70
UniRef100_UPI000042CC69 UPI000042CC69 UniRef100 entry 270 4e-70
UniRef100_UPI000036FA32 UPI000036FA32 UniRef100 entry 269 9e-70
UniRef100_Q6AI22 Hypothetical protein DKFZp686H16106 [Homo sapiens] 268 1e-69
UniRef100_Q9V628 CG13185-PA [Drosophila melanogaster] 258 1e-66
UniRef100_UPI000021BFA6 UPI000021BFA6 UniRef100 entry 243 7e-62
>UniRef100_Q9ZW94 F5A8.4 protein [Arabidopsis thaliana]
Length = 5138
Score = 698 bits (1801), Expect = 0.0
Identities = 473/1447 (32%), Positives = 749/1447 (51%), Gaps = 128/1447 (8%)
Query: 24 WNCSHHGTYLPKFLLSAARALFQQIIYAHRKSFDADQYAAIKYNFSSFERNMATEESIHL 83
W S T+ + IIY H+KSF+++ + AIK F + E+ + I
Sbjct: 2860 WQLSDSVTFYADSACENSYRCSDSIIYTHQKSFESETFVAIKSVFHAIEKKQNKMDGIQN 2919
Query: 84 VSTLVGSSRHHRLKNSVNKFIVPLLRELYIQSTTTDFNFNYTIGCAWAHIGALRIHLLLS 143
+ +L+GSS H++LK+ + F+ PL + LY S++ +F N +G AW ++G LR HLL S
Sbjct: 2920 LISLIGSSSHNKLKSVTHSFVGPLAKRLYSDSSSNEFYCN--LGLAWLYLGGLRFHLLNS 2977
Query: 144 YNEVDPVMKYYCKYTQLEETISSLELEIQVRKECGYLSGQFLTVEADKRKAERLEKLQAE 203
+ +DP MK CK +LEE ISSLEL I+VR ECGYLSG + D+ L KL+ E
Sbjct: 2978 LDVIDPAMKITCKLLKLEEKISSLELNIKVRGECGYLSGLLYSGNNDESSEHTLSKLKTE 3037
Query: 204 LRKLQRKIVFRSESWKYKKLMNECDEFLKHIASLEVLVGNVEAEDLQQVIDRTHSWQETA 263
++LQRK++FRS+ KY+ L DEF + LV ++E D QV+++ +WQETA
Sbjct: 3038 HKRLQRKVIFRSDPKKYQDLRRALDEFAGFLTRPISLVNDIEVLDWNQVVEQVFNWQETA 3097
Query: 264 MCFINRLTDEYTAYNDIIQPIQVAVYEMKFGLSLVLSSFLEKEYLRKVGHENINLVTDMI 323
+ FI+R++ +Y+ Y DI QPIQV+VYEMK GLSL +S L + L + + ++ V + I
Sbjct: 3098 ISFIDRMSSDYSEYVDITQPIQVSVYEMKLGLSLFVSGALLGKLLNRFDIDMVDSVMETI 3157
Query: 324 YILMRFPRAASWKFISVEDVGVDLHSSYKLDF-GTDFYLNMGLIERLITLSSGVSADKKV 382
Y LMRFPR +S + + LH S+ + L++GL+ +LI++SS + +K
Sbjct: 3158 YALMRFPRDSSIASTTYTECLPPLHLSHGANSRAKSLGLDVGLLHKLISVSSAEDS-RKA 3216
Query: 383 SAMRCRASIYWNILVQIAYSIANAKIIDRESYMLLHKIFDEFASLWMSMKVYAKSKSDHD 442
S ++ + ++Y N+ ++ +AN ++D S+ LL KI+ E A +WM MK AK+K+D+
Sbjct: 3217 SELQLKVALYKNLHARVLQFVANTGLLDEASFELLDKIYVELARIWMEMKFQAKTKADNL 3276
Query: 443 AQQFKFKPRAFQIESIMELEIPALANSSATEAFSDWKEFSYEEKS---ADNMESSEECEI 499
+KF+ R F+I+S+ME++I AL E+FS+W+E+ ++ + D ++ E
Sbjct: 3277 PGLYKFRSRDFKIDSVMEVDISALGKYFPNESFSEWQEYLADDDTKNVKDMTHIDQDEEN 3336
Query: 500 LDEEWKHLEESILDNVVLIHSQLFGSGDLVQ------APGIFEISDEDRLHSFSESYKLG 553
L+++W ++E LD++ H++LFG DL + G F I+D RL SF++SY+LG
Sbjct: 3337 LEDDWDLIQEH-LDSIYSTHNELFGFCDLSEKTIYSIQSGRFCITDSRRLDSFTDSYELG 3395
Query: 554 INLIKGAHSSNLASLDAKLIPEHLFYLSIDYRRKFHSSSKSANRYNFYKDSNAHEIEQML 613
+++IKG +SLDAKL+PEHL L ++ ++ F S+ +SA++YNFYKD + E+ +M+
Sbjct: 3396 VSMIKGLRGLFTSSLDAKLVPEHLLRLCLENKKNFTSNYQSASKYNFYKDLDGPELGKMV 3455
Query: 614 KVLAPLRQQITSLLNEWEEQNDLQRFLDVIDMLLTLPSDIPLAKAFSGLQFLLHKAQVMQ 673
K L PL+Q+I SLL E E+ LQ+ V+ MLL +PS PLAKA SGLQFLL K +Q
Sbjct: 3456 KFLTPLQQRINSLLQEREDHPGLQKLSGVLQMLLAIPSSTPLAKALSGLQFLLCKVHKLQ 3515
Query: 674 ENHSKFTFSNQLKSVFDLMSSWHKMELGSWPVLLDEVMDQYENNAKKSVLSSSIHYF*SI 733
E K S+ L+ + L SSW K+E WP LLDEV DQYE NA+K + F ++
Sbjct: 3516 EEGCKLPISDLLEPIISLASSWQKVEFERWPTLLDEVQDQYELNARKFCFRRMLWKFQNM 3575
Query: 734 -NFPKSNFYFSYESCSLEDFIQTSSFGEFRKRLQLLYAFLGQNHTSACLKINSSNIVFFL 792
P F + L+ +I SS QL+ L TS +S F+
Sbjct: 3576 KTSPFHKVSFLKDLKGLQHYILKSS--------QLIAPPLFLQLTSNLTVFDSR---FYF 3624
Query: 793 HCWTLQLLSDGAVNILVQYVWILCAVLTNHIDASRKEILTELKDLVKLCRWEQDKSYSSI 852
+ + + NI Y+ L V+ +D +RK + TELK+++KLCRWE+ +Y
Sbjct: 3625 DSDSHKRRVEMCYNIFGFYIQFL-PVVMEQLDLNRKNVETELKEVLKLCRWERPDNYLYN 3683
Query: 853 ENLKKSRQKLKKLIKKHTDILQEPMDKLIRD----------VLHKGSISGVSDL------ 896
E K++RQK+KKLI+K TD+L+ P+ + D +L + G SD+
Sbjct: 3684 ETTKRTRQKVKKLIQKFTDMLRLPVMLVKPDLTKERAQFLPLLDPDLMDGASDMRIEVLV 3743
Query: 897 --------------------PLFSDENRLYQE---------------------GWKDVWH 915
L R +QE WK++W
Sbjct: 3744 SALDAEQLRDRSSWYVVWWNKLKESVGRFHQEMHYKTLLMGAEHQYSSPVYQGDWKNLWS 3803
Query: 916 MIENIYIKAVDSGNIWKEDKNNQRKSRALSDLLNLLKTSGLSQRK------STHKVKIVD 969
+ I ++W+ + K RAL +LL LL++SGL + K S H ++
Sbjct: 3804 TVARIGETIAGCSDLWRNSDRDVAKKRALFELLKLLESSGLQKHKFENIEMSNHFKGLLY 3863
Query: 970 SPVHPWK---LMVK*KIKMPLKKAHLRSGRQLLSITSRVLCVCVFCRKRYASILIKI*L- 1025
P + K L+ K + ++ + RV F K AS+ + + +
Sbjct: 3864 QPAYDPKHLLLLTHTKSNIHPSMGVEDQNKENSLVEWRVANEFYF--KSLASVQLMLNID 3921
Query: 1026 ----------LNRSSSFLSQLVQIQQDQLAAASVFSEKLKCFREFATTMGKLFSFSSPTD 1075
+ R+ SFL+ LV+IQ+ Q +A F+E FR+ ++ +L S D
Sbjct: 3922 RKHSDVTAEQVKRAISFLNHLVEIQRQQRKSAYAFAELFNRFRQCVLSLARLLGDSVGAD 3981
Query: 1076 NSKSYMCSIVPPNQLATYKCMWQQKQLFDSLCATSNGELLLLRILENSHLNTCQRTRPSA 1135
+ S P NQ A + C+W QKQLFD++ A E LLR + ++HL++CQ + S+
Sbjct: 3982 RKDDSVFSF-PQNQHAVFNCLWLQKQLFDNITAMLLEESALLRTVGSTHLDSCQAVKTSS 4040
Query: 1136 SEMTASIEEFLPVFCKSKESLDCYLIGGSKAVTTIASSHLSVVTQEMEQLVSENFKVIKD 1195
+ + IE +P+ SK SLD L+ + + T +SS VTQ M Q++ +NF + D
Sbjct: 4041 RSLLSFIEILIPIAQNSKASLDRLLLDCNGFIITPSSSLKQFVTQHMVQVLRQNFDQLTD 4100
Query: 1196 FKDHFLVLQANGMDRSSVKNVLIHHFQEIIDKAKSIEEEFITAKNENSNPVDLSEKDHFC 1255
++ N ++S ++VL+ F + + K + E N + K+
Sbjct: 4101 LENQISSFCENN-EKSYCRDVLLSQFSPVFKEGKLLAENLNCLLNVRDQSTGMEPKERLF 4159
Query: 1256 GRQCAEPNARFDEALKSTYQHITSVLQSLCS----PSTIPSMINLGSWELQFVA---NLS 1308
+E L S + ++ V+ LCS + +N+ +W+ F +L+
Sbjct: 4160 ----------LEENLASIFANVKDVIGKLCSYKDGSLSQEEEMNITTWDGLFKKAENDLN 4209
Query: 1309 LDMLCDDLFKTITFGAKLVNCCDNNISSSSKVGAHFQNLHTLVDLLLKFSDELLKNFFAM 1368
LD LC L ++ +L+N ++ S+ VG + L +DLLL F D LK F A+
Sbjct: 4210 LDNLCKLLSESFGSIEQLLN---SSGVLSAGVGDQLKQLQAFLDLLLSFGDCYLKEFLAI 4266
Query: 1369 HKS*QLM 1375
K+ L+
Sbjct: 4267 SKTVSLI 4273
Score = 583 bits (1503), Expect = e-164
Identities = 348/856 (40%), Positives = 505/856 (58%), Gaps = 70/856 (8%)
Query: 1450 KEEQEESKEVPGNDNTGIEMDQDFQADAVSLSEDSSENEDCDG-ENEELESEMGPTGPDS 1508
+EE++E +V G N GIEM +F S+SED E+++ +G E+E L++ +G G D+
Sbjct: 4322 EEEEKEQDDVLGK-NKGIEMSDEFDGKEYSVSEDEEEDKEDEGSEDEPLDNGIGDVGSDA 4380
Query: 1509 EAVGEKIWDQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDD--STSDQSGD-DSCDE 1565
E EK W+++E++ ++ EK ESGPS+ D D ++ELRAKDD T+D+ + ++ D+
Sbjct: 4381 EKADEKPWNKDEEDEEENMNEKNESGPSIVDKDTRSRELRAKDDGVETADEPEESNTSDK 4440
Query: 1566 GDAQNDEAAAQNEFDDEENGDDVNMDKEAAHSDATGLKPDEPDHSSDMEIDLNANEDVDP 1625
+ NDE Q++FDD +N ++ KE A GL PD + D +++++ E+V+
Sbjct: 4441 PEEGNDENVEQDDFDDTDNLEEKIQTKEEA---LGGLTPDVDNEQIDDDMEMDKTEEVEK 4497
Query: 1626 IEEGDQE-------GHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEHQEND 1678
+ QE H + EN +QE+ P +E ME + S +K++ G + ++
Sbjct: 4498 EDANQQEEPCSEDQKHPEEGEN-DQEETQEPSEENMEAEAEDRCGSPQKEEPGNDLEQEP 4556
Query: 1679 DMNSMDPKNDTSE---SSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNSHHDFG 1735
+ ++ K SE + N +S V+ SQ+ G+ + A Q NLS + D
Sbjct: 4557 ETEPIEGKEVMSEDMMKPNFRNDNISGVESGSQNPHGSNVLGAGSTAPQENLSAT--DVT 4614
Query: 1736 NPAVTG-GFPSSDMSEMDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEKQTNPSRSTGD 1794
+ PSS +EM++ M++ +N + PK PQ++ S +Q+ + NP R+ GD
Sbjct: 4615 DELTDSMDLPSSSNTEMNLMMTNMANGETLTDNLPKMEFPQNQSSTAQQTKVNPYRNVGD 4674
Query: 1795 ALDFRKEKINVSGDLPEDNIEHHGEMDDNNADEYGYVSEFEKGTTQALGPATLEQVDRNI 1854
AL KE++ +S DL E E EM+D +A EYG+ S+F+ GT+QALGPA EQV+ ++
Sbjct: 4675 ALKEWKERVRISSDLGEKQ-EAENEMEDPDASEYGFASQFDAGTSQALGPALPEQVNTDM 4733
Query: 1855 DVDKVDTESRAGED---ANLQLEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKS-QDDG 1910
+ + E AG + + ++ N E S N +Q P +++ Q++
Sbjct: 4734 REGESEEEKLAGNQDDVSPMDIDDLNPENKPAVQSKPSISNSIAEQVQEPDTDRTHQENS 4793
Query: 1911 SVKPLGSANIDPESHLEDLISISRSYLGENTHKLSQLSVNDEELGKYHEPCDAPDHVKDN 1970
+ G N S ++ ++S+ ++LGE L ++ V D + + + PD + N
Sbjct: 4794 PIHNFGDGN----SRMDSMVSVDNTFLGEEACNLDRMQVTDNDSESNQDNQEDPD-ARSN 4848
Query: 1971 ATALWRRYELSTTKLSQELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKVIQFIASYYRM 2030
A LWRR EL T K SQEL EQLRL+LEPT+ASKL G Y+TGKRI+MKKVI +IAS+YR
Sbjct: 4849 AVVLWRRCELLTAKPSQELAEQLRLILEPTLASKLSGDYRTGKRINMKKVIPYIASHYRK 4908
Query: 2031 DKIWLRRTRPNKRDYQVVIAVDDSHSMSESCCGDVAVEALVTVCRAVSQLEMGSLAVASF 2090
DKIWLRRT+PNKRDYQVVIAVDDS SMSES CGD A+ AL TVCRA+SQLE+GSLAVASF
Sbjct: 4909 DKIWLRRTKPNKRDYQVVIAVDDSRSMSESGCGDFAIRALATVCRAMSQLELGSLAVASF 4968
Query: 2091 GTKGNINLLHDFDSPFTAESGVKVSRIYTSLVFFFIDISTVHLLNMLKGSDCSFLTEEQM 2150
G +G+I +LHDF FT ESG+K M
Sbjct: 4969 GKQGSIKMLHDFGQSFTTESGIK------------------------------------M 4992
Query: 2151 VSNLTFKQENTIADEPVVDLLKFLTNKLDAAVVKARLPSGHNPLQQLVLIIADGRFHEKD 2210
+SNLTFKQEN I D+PVV+LL+ + L+ R G NPLQQLVLII DG+FHE++
Sbjct: 4993 ISNLTFKQENLIEDQPVVNLLRNMNEMLENLASTRRQSYGSNPLQQLVLIIGDGKFHERE 5052
Query: 2211 NLKRCVREALASNRMVAFLLLDNSQESIMDLMEASFEGGKMKFSK--YMDSFPFPYYIVL 2268
LKR VR L RMV +LLLD++++S+ DL + ++G + + K Y+DSFPFPYYIVL
Sbjct: 5053 KLKRTVRSFLQQKRMVVYLLLDDAEQSVFDLADYVYDGERRPYKKMNYLDSFPFPYYIVL 5112
Query: 2269 RNIEALPRTLANLLRQ 2284
R+IEALPRTL ++LRQ
Sbjct: 5113 RDIEALPRTLGDVLRQ 5128
Score = 43.9 bits (102), Expect = 0.060
Identities = 67/361 (18%), Positives = 129/361 (35%), Gaps = 53/361 (14%)
Query: 1575 AQNEFDDEENGDDVNMDKEAAHSDATGLKPDEPDHSSDMEIDLN----ANEDVDPIEEGD 1630
++NE DD+ D + D G K +E + D + N +++ D E
Sbjct: 4292 SKNEEDDDSKVDKSEAAEGTGMGDGVGAKDEEEEKEQDDVLGKNKGIEMSDEFDGKEYSV 4351
Query: 1631 QEGHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEHQENDDMNSMDPKNDTS 1690
E ++ E+ EDE P D + + ++ + + EK E E ++MN + +
Sbjct: 4352 SEDEEEDKEDEGSEDE--PLDNGIGDVGSDAEKADEKPWNKDEEDEEENMNEKNESGPSI 4409
Query: 1691 ESSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAVTGGFPSSDMSE 1750
D + ++ D ++ + + S + + + N N D F +D E
Sbjct: 4410 VDKDTRSRELRAKDDGVETADEPEESNTSDKPEEGNDENVEQD--------DFDDTDNLE 4461
Query: 1751 MDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEKQTNPSRSTGDALDFRKEKINVSGDLP 1810
I + + GG + P Q + +K + KE N + P
Sbjct: 4462 EKIQTKEEA-LGGLT---PDVDNEQIDDDMEMDKTE----------EVEKEDANQQEE-P 4506
Query: 1811 EDNIEHHGEMDDNNADEYGYVSEFEKGTTQALGPATLEQVDRNIDVDKVD-----TESRA 1865
+ H E +N+ +E T E + N++ + D +
Sbjct: 4507 CSEDQKHPEEGENDQEE------------------TQEPSEENMEAEAEDRCGSPQKEEP 4548
Query: 1866 GEDANLQLEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKSQDDGSVKPLGSANIDPESH 1925
G D + E + E V + ++ N + D + V SQ+ LG+ + P+ +
Sbjct: 4549 GNDLEQEPETEPIEGKEVMSEDMMKPNFRNDNIS-GVESGSQNPHGSNVLGAGSTAPQEN 4607
Query: 1926 L 1926
L
Sbjct: 4608 L 4608
>UniRef100_Q869L3 Similar to midasin, a large protein with an N-terminal domain, a
central AAA domain (With similarity to dynein) composed
of 6 tandem AAA protomers, and a C-terminal M-domain
containing MIDAS (Metal Ion Dependent Adhesion Site)
sequence motifs; Mdn1p [Dictyostelium discoideum]
Length = 5864
Score = 317 bits (812), Expect = 3e-84
Identities = 268/971 (27%), Positives = 441/971 (44%), Gaps = 196/971 (20%)
Query: 1448 QKKEEQEESKEVPGNDNTGIEMDQDFQADAVSLSEDSSENED--CDGENE-ELESEMGP- 1503
+K E+++E KE D G +M DF+ + + +D +++ED D NE E + EMG
Sbjct: 4947 EKDEDEDEEKEEKDEDE-GFDMQDDFEGEMHDIKKDENKDEDKKDDPNNEKENDKEMGDL 5005
Query: 1504 TGPDSEAVGEKIWDQ---NEDETPDDTGEKYESGP----SVKDGDGSNKELRAKDDSTSD 1556
P+ V EK+WD+ ++E D+ G+ E+ + +DG N + + DD D
Sbjct: 5006 EKPEDNVVDEKLWDEQDVQDEEEQDEEGKGDETNSEEMMAKQDGKDDNDDDKKDDDKKDD 5065
Query: 1557 ------------------QSGDDSCDEGDAQN----DEAAAQNEFDDEENGDDV---NMD 1591
+ DD ++G N D A+ +++F EEN DDV +
Sbjct: 5066 KKKKKEENGKPDENEEGEEGKDDEEEDGKDDNKNADDGASDEDDFGQEENEDDVINQEQE 5125
Query: 1592 KEAAHSDATG---------LKPDEPDHSSDMEIDLNANEDV-DPIEEGDQEGHDDSAE-- 1639
KE H D G L+ ++PD + + + +D DP++E D G D S E
Sbjct: 5126 KEENHGDPRGDDQMEIPEDLELEDPDEGKEDDEQQDGGDDFKDPLDEMD--GDDVSKEEE 5183
Query: 1640 -----NGNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEHQENDDMN--SMDPKNDTSES 1692
+G++++E+ + +E + D ++D +E+Q D N S++P+ D E
Sbjct: 5184 KKKELDGDEKEESDQDGDEEKEDEEKEDGDEDEDKEDKENQPIDPSNVDSINPEGDEPEK 5243
Query: 1693 SDVVNPQVSNVDLASQSKSDLQTSGSE-------NIASQSNLSNSHHDFGNPAVTGGFPS 1745
P+ L + + D SE S+SN+SN+ + + + +
Sbjct: 5244 E---QPEEDQTSLTTNEQQDETPKDSEQPLGVKDKTGSKSNVSNTDEEMKDES------N 5294
Query: 1746 SDMSEMDINMSD---SSNTGGFSKTQPKSHLPQHEHSFSQEKQ----TNPSRSTGDALDF 1798
D ++ D M+ S N G K PQ +KQ NP RS GDA
Sbjct: 5295 QDNADDDSGMTQPTPSENDTGALKNLKSQPPPQSSAQQPPKKQKQVDPNPYRSMGDANKE 5354
Query: 1799 RKEKINVSGDLPEDNIEHHGE-----------MDDNNADEYGYVSEFEK-----GTTQAL 1842
K+++N+ + E+ E E +N +Y ++ + EK T QAL
Sbjct: 5355 WKKRLNLKQEQEEEEEEQSSEPKEKAPKQDPNAKENENQDYEFIKDDEKLDKDEETDQAL 5414
Query: 1843 GPAT----------------LEQVDRNIDVDKVD-------TESRAGEDANLQL-EKQNS 1878
AT EQ + +D+D+ D E +D+ QL E +
Sbjct: 5415 AAATDTQLQDIPQNKAQDDQAEQEEDQMDIDEEDDMDVDHKQEVEHQDDSKQQLDENKKI 5474
Query: 1879 EIDSVSNSSLLPKNEKRDQANMPVMEKSQDDGSVKPLGSANIDPE---SHLEDLISISRS 1935
+ + L + EK + +EK Q DG L N + LE+L ++ +
Sbjct: 5475 SMSKLKQDQLKQQKEKEKEK----LEKDQQDGQDDELDGLNQKEQFTKEQLENLTNLDKE 5530
Query: 1936 YL---------------GENTHKLSQLSVNDEELGKYHEPCD----APDHVKDNATALWR 1976
++ + + + E+L + + + + T LW+
Sbjct: 5531 KAVLDDGDDQEMEQDGDQDDEESVEEKKLTREDLDRMRQELEQYKIENSSNPEIGTELWK 5590
Query: 1977 RYELSTTKLSQELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKVIQFIASYYRMDKIWLR 2036
+YE T LSQ+L EQLRL+LEPT+A+KLQG YK+GKRI+MKKVI +IAS ++ DKIWLR
Sbjct: 5591 KYEQLTNDLSQDLCEQLRLILEPTLATKLQGDYKSGKRINMKKVIPYIASQFKKDKIWLR 5650
Query: 2037 RTRPNKRDYQVVIAVDDSHSMSESCCGDVAVEALVTVCRAVSQLEMGSLAVASFGTKGNI 2096
RT+PNKR YQV++A+DD+ SM+ G A+EA+ + RA+S+LE+G L + FG ++
Sbjct: 5651 RTKPNKRQYQVLLAIDDTESMAAYHSGGFALEAMTMISRAMSRLEVGQLGIVRFGE--DV 5708
Query: 2097 NLLHDFDSPFTAESGVKVSRIYTSLVFFFIDISTVHLLNMLKGSDCSFLTEEQMVSNLTF 2156
L+H FD F+ ++G ++++ F
Sbjct: 5709 QLVHSFDQVFSDQTG------------------------------------PEIITQFKF 5732
Query: 2157 KQENTIADEPVVDLLKFLTNKLDAAVVKARLPSGHNPLQQLVLIIADG-RFHEKDNLKRC 2215
+Q T +++ FL+ L + + SG P QLV I++DG + + K+
Sbjct: 5733 QQTKT-------NMVNFLSKTLQIMDMNKQSSSG-EPAMQLVFIVSDGWSLRDPETTKKY 5784
Query: 2216 VREALASNRMVAFLLLDN--SQESIMDLMEASFEGGKMKFSKYMDSFPFPYYIVLRNIEA 2273
+REA N + F+++DN + SI+D SF GK++ + YM FPF YY++LR++
Sbjct: 5785 LREASIKNVFIVFIVIDNPVNNNSILDFESISFNNGKIQRTNYMSEFPFMYYVILRSLNN 5844
Query: 2274 LPRTLANLLRQ 2284
+P L++ LRQ
Sbjct: 5845 IPSILSDTLRQ 5855
Score = 177 bits (448), Expect = 5e-42
Identities = 211/953 (22%), Positives = 382/953 (39%), Gaps = 152/953 (15%)
Query: 78 EESIHLVSTLVGSSRHHRLKNSVNKFIVPLLRELYIQSTTT----DFNFNYTIGCAWAHI 133
+E I + L+ S + ++P L L + T G +
Sbjct: 3378 DELIENIKELIIQSNDKSFNEKSKQLLLPCLDILLCLDDKVLYKDELKLQSTFGRLQLLL 3437
Query: 134 GALRIHLLLSYNEVDPVMKYYCKYTQLEETISSLELEIQVR----KECGYLSGQFLTVEA 189
R+ + + +DP KY +E L+ EI++R K+ G L ++
Sbjct: 3438 NTFRLIMFVPSGSIDPTQKYDVILQYSKEHSKQLQDEIEIRTIIEKQYTGKDGTSLVIDE 3497
Query: 190 DKRKAERLEKLQAELRKLQRKIVFRSESWKYKKLMNECDEFLKHIASLEVLVGNVEAEDL 249
+K + +++ +L +KI R ++++L + +F H +++E ++ DL
Sbjct: 3498 LVQKKQSIDQ---KLALDSKKITLRPIPSQFEELYRDVSQFSNHFSNIEKIIDLFSKLDL 3554
Query: 250 QQV---------------------------------IDRTHSWQETAMCFINRLTDE-YT 275
QV + WQE A FI + Y+
Sbjct: 3555 SQVKNEFNLEVESEGGDNQQQQENNTSANSSYNQMILSTEQMWQEKANHFIQSCEKKFYS 3614
Query: 276 AYNDIIQPIQVAVYEMKFGLSLVLSSFLEKEYLRKVGHEN--INLVTDMIYILMRFPRAA 333
Y DII PI AVY+MK GL ++ SF +K K+G + ++ L +FPR
Sbjct: 3615 RYRDIIVPIITAVYQMKSGLRMMSVSFKQKVQDNKLGGNQGITKQIQKVLLSLTQFPRIN 3674
Query: 334 SWKFISVEDVGVDLHSSYKLDFGTDFYLNMGLIERLI--TLSSGVSADKKVSAMRCRASI 391
S + + ++ T+ N L+++L ++ + +++ + C +
Sbjct: 3675 S---VDINSKITTTSTTTTATTTTNTTSNNILLDKLTLDSIKDMMKFNQRTNQDNCNGGL 3731
Query: 392 Y---------WNILVQIAYSIANAKIIDRESYMLLHKIFDEFASLWMSMKVYAKSKSDHD 442
+ L QI ++N+ +D ++ + IF F W + + K + +
Sbjct: 3732 QNFKVIGLLLRSSLCQIYSQLSNSNYLDVDNLEAIDSIFRIFVQEWRFQEEEKRKKEELE 3791
Query: 443 AQQFKFKPRAFQIESIMELEIPALANSSAT--EAFSDWKEFSYEEKSADN--------ME 492
Q+FK+K + ++E+ E + S + F D + + E D+ E
Sbjct: 3792 NQEFKYKVQTHKMETKEEKDEKVFLTSFPNFYKDFEDLEVANVVENQIDDDNDEENKDKE 3851
Query: 493 SSEECEILDEEWKHLEESILDNVVL-----IHSQLFGSGDLVQAPGI---FEISDEDRLH 544
++E + E+ +S ++N + IH +F D + P + +SD DR
Sbjct: 3852 NNESNVLTSEDGSMFFKSSINNEEILQLCSIHRDIFKHLDGIPIPKEQQQWTLSDRDRSE 3911
Query: 545 SFSESYKLGINLIK----------------GAH---SSNLASLDAKLIPEHLFYLSIDYR 585
F Y L+K G+H +SNL + P + Y +D +
Sbjct: 3912 LFQLFYSSSYLLMKILNQRSGDMEFDQLSLGSHILSASNLKETLSIRPPSLITYSKLDEK 3971
Query: 586 RKF-------HSSSKSAN----------------RYNFYKDSNAHEIEQMLKVLAPLRQQ 622
+F + SK N YN Y+DSN EI + + L R++
Sbjct: 3972 FRFLKTSSYLYKKSKGINDDDGDNQVVDVIHQKKTYNIYRDSNISEIGIIREPLISFRKR 4031
Query: 623 ITSLLNEWEEQNDLQRFLDVIDMLLTLPSDIPLAKAFSGLQFLLHKAQVMQENHSK-FTF 681
+ LL E+ EQ +L + +ID L+T P+ PLAK +GL+ LL K+ + SK +
Sbjct: 4032 VFELLVEYPEQANLTLMVKLIDRLMTYPATDPLAKILTGLELLLRKSLEWESFASKAVSI 4091
Query: 682 SNQLKSVFDLMSSWHKMELGSWPVLLDEVMDQYENNAKKSVLSSSIHYF*SINFPKSNFY 741
N L + L+ W K+E+ SWP + E A+ L S + IN S+
Sbjct: 4092 QNHLNEISSLIVRWRKLEIESWP----SIFQSQEKEAEVKALKSWFILYDLINDEPSSPE 4147
Query: 742 FSYESCS-----LEDFIQTSSFGEFRKRLQLLYAFLGQNHTSACLKINSSNIVFFLHCWT 796
E+ S L+ ++ +SS G+F R++LL +F Q +++ L S N +
Sbjct: 4148 LEDENLSKNFHTLQQYLYSSSLGDFLTRIELLKSFYKQLNSTIKLIGTSKNTNY------ 4201
Query: 797 LQLLSDGAVNILVQYVWILCAVLTNHIDASRKEILTELKDLVKLCRWEQDKSYSSIENLK 856
Q LSD NI +Y + + + S K I + + ++L RW+ ++ + E LK
Sbjct: 4202 KQKLSDIIYNIF-KYFENFISRFEDRLAKSIKPIEDKALEFIRLSRWDDNRLLTQYERLK 4260
Query: 857 K----SRQKLKKLIKKHTDILQEPMDKLIRD----------VLHKGSISGVSD 895
+ S + L K+ K+ ++L +P+ + VLH G+ + + D
Sbjct: 4261 QHIEVSHRNLAKVTIKYKNVLAQPLHDIFTQIENELDIPPLVLHSGAATILED 4313
Score = 63.2 bits (152), Expect = 9e-08
Identities = 89/450 (19%), Positives = 171/450 (37%), Gaps = 68/450 (15%)
Query: 1481 SEDSSENEDCDGENEELESEMGPTGPDSEAVGEKIWDQNEDETPDDTGEKYESGPSVKDG 1540
++ + E +G E ++ TG E G+K D ++ E ++D
Sbjct: 4893 ADGGDDGEGGEGGRSNFEDDVEGTGM-GEGKGKK-----------DVSDQLEDQGQIEDT 4940
Query: 1541 DGSNKELRAKDDSTSDQSGDDSCDEGDAQNDEAAAQ------NEFDDEENGDDVNMDKEA 1594
+ KE + +D+ + D+ DEG D+ + +E DE+ DD N +KE
Sbjct: 4941 NTQKKEEKDEDEDEEKEEKDE--DEGFDMQDDFEGEMHDIKKDENKDEDKKDDPNNEKEN 4998
Query: 1595 AHSDATGLKPDEPDHSSDMEIDLNANEDVDPIEEGDQEGHDD--------SAENGNQEDE 1646
KP++ + ++ L +DV EE D+EG D + ++G +++
Sbjct: 4999 DKEMGDLEKPED----NVVDEKLWDEQDVQDEEEQDEEGKGDETNSEEMMAKQDGKDDND 5054
Query: 1647 TCPPDEIMEEAHTEVDVSSEKDDLGQEHQENDDMNSMDPKNDTSESSDVVNPQVSNVDLA 1706
D+ ++ + + K D +E +E D D K+D + D A
Sbjct: 5055 DDKKDDDKKDDKKKKKEENGKPDENEEGEEGKDDEEEDGKDDNKNADDG----------A 5104
Query: 1707 SQSKSDLQTSGSENIASQSNLSNSHHDFGNPAVTGGFPSSDMSEMDI----NMSDSSNTG 1762
S Q +++ +Q +H G+P + E++ D G
Sbjct: 5105 SDEDDFGQEENEDDVINQEQEKEENH--GDPRGDDQMEIPEDLELEDPDEGKEDDEQQDG 5162
Query: 1763 GFSKTQPKSHLPQHEHSFSQEKQTNPSRSTGDALDFRKEKINVSGD-LPEDNIEHHGEMD 1821
G P + + S +EK+ GD KE+ + GD ED + G+ D
Sbjct: 5163 GDDFKDPLDEMDGDDVSKEEEKK---KELDGD----EKEESDQDGDEEKEDEEKEDGDED 5215
Query: 1822 DNNADEYGYVSEFEKGTTQALGPATLEQVDRNIDVDKVDTESRAGEDANLQLEKQNSEID 1881
++ D+ Q + P+ ++ + N + D+ + E + +L +Q E
Sbjct: 5216 EDKEDK----------ENQPIDPSNVDSI--NPEGDEPEKEQPEEDQTSLTTNEQQDETP 5263
Query: 1882 SVSNSSLLPKNEKRDQANMPVMEKSQDDGS 1911
S L K++ ++N+ ++ D S
Sbjct: 5264 KDSEQPLGVKDKTGSKSNVSNTDEEMKDES 5293
Score = 49.7 bits (117), Expect = 0.001
Identities = 73/391 (18%), Positives = 142/391 (35%), Gaps = 51/391 (13%)
Query: 1564 DEGDAQNDEAAAQNEFDDEENGDDVN-----------MDKEAAHSDATGLKPDEPDHSSD 1612
D GD ++ F+D+ G + ++ + D K +E D D
Sbjct: 4894 DGGDDGEGGEGGRSNFEDDVEGTGMGEGKGKKDVSDQLEDQGQIEDTNTQKKEEKDEDED 4953
Query: 1613 MEID-LNANEDVDPIEEGDQEGHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSEKDDLG 1671
E + + +E D ++ + E HD + ED+ P+ E D+ +D++
Sbjct: 4954 EEKEEKDEDEGFDMQDDFEGEMHDIKKDENKDEDKKDDPNNEKENDKEMGDLEKPEDNVV 5013
Query: 1672 QEHQENDDMNSMDPKNDTSESSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNSH 1731
E ++ + + D D N S +A Q D ++ + +
Sbjct: 5014 DEKLWDEQDVQDEEEQDEEGKGDETN---SEEMMAKQDGKDDNDDDKKDDDKKDDKKKKK 5070
Query: 1732 HDFGNPAVTGGFPSSDMSEMDINMSDSSNTGGFSKTQPKSHLPQHEHSF---SQEKQTNP 1788
+ G P E + D+ N + + ++E QEK+ N
Sbjct: 5071 EENGKPDENEEGEEGKDDEEEDGKDDNKNADDGASDEDDFGQEENEDDVINQEQEKEENH 5130
Query: 1789 SRSTGDALDFRKEKINVSGDL--------PEDNIEHHG------EMDDNNADEYGYVSEF 1834
GD +++ + DL ED+ + G +D+ + D+ E
Sbjct: 5131 GDPRGD------DQMEIPEDLELEDPDEGKEDDEQQDGGDDFKDPLDEMDGDDVSKEEEK 5184
Query: 1835 EKGTTQALGPATLEQVDRNIDVDKVDTESRAGEDANLQLEKQNSEIDSVSNSSLLPKNE- 1893
+K L E+ D++ D +K D E G++ + +K+N ID + S+ P+ +
Sbjct: 5185 KK----ELDGDEKEESDQDGDEEKEDEEKEDGDEDEDKEDKENQPIDPSNVDSINPEGDE 5240
Query: 1894 ------KRDQANMPVMEKSQD--DGSVKPLG 1916
+ DQ ++ E+ + S +PLG
Sbjct: 5241 PEKEQPEEDQTSLTTNEQQDETPKDSEQPLG 5271
>UniRef100_UPI00002366BE UPI00002366BE UniRef100 entry
Length = 4917
Score = 303 bits (775), Expect = 5e-80
Identities = 246/886 (27%), Positives = 400/886 (44%), Gaps = 129/886 (14%)
Query: 1444 LSMMQKKEEQEESKEVPGNDNTGIEMDQDF---QADAVSLSEDSSENEDCD-GENEELES 1499
LS + ++E+QE + E + MDQ+ + ED ++E D GE ++++
Sbjct: 4106 LSELAQQEQQEGAGEDIDKSKDAVNMDQEDLKGEEGEHEEEEDGEKDESGDEGEEDDIDE 4165
Query: 1500 EMGPTGP-DSEAVGEKIWDQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQS 1558
E+G D AV EK+WD DE +T + G S D + E Q
Sbjct: 4166 EVGSVNDLDVSAVDEKMWDGGHDEQQKETENEEGKGASEADQQAAAPE----------QK 4215
Query: 1559 GDDSCDEGDAQNDEAAAQNEFDDEENGDDVNMDKEAAHSDATGLKPDEP---DHSSDMEI 1615
+ +EGD + +EA ++E ++EE DD D T + E D +M++
Sbjct: 4216 EGEKGEEGDKEGEEAEEEDEEEEEEAPDDEGEAVGREDMDVTDPQAPEQETLDLPDEMQL 4275
Query: 1616 DLNANEDVDPIEEGDQEGHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEHQ 1675
D + +D + G +G DD + N E PDE +EE D+ E++++ + +
Sbjct: 4276 D-GDEKGMDDEDFGSDDGLDDLPDAPNDEQMDEKPDENIEEEGPG-DLPGEEEEINPDEE 4333
Query: 1676 ---ENDDMNSMDPKNDTSESSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNSHH 1732
E ++ N+ + +++ ++ P+ + D + D +T+G E S+
Sbjct: 4334 APPEEENANAAEGEDEAQAPAE--EPEETQQDEFLAQRDDNETAGEEVAPSE-------- 4383
Query: 1733 DFGNPAVTGGFPSSDMSEMDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEKQTNPSRST 1792
AV GG + + S ++ S T P Q + + ++ R
Sbjct: 4384 -----AVNGGLGAEQDQNQEKGASGNAQQQDGS-TDPSVEPKQQTGAAKEGEENERHRDA 4437
Query: 1793 GDALDFRKEKINVS-----GDLPED-----------NIEHHGEMDD--------NNADEY 1828
G D E + GD+ E + + GE D+ +AD
Sbjct: 4438 GGGDDINPEDPQLQAFKKLGDVLEQWHRRQKEIMNASKQEEGETDEPLPQDTEMGDADFE 4497
Query: 1829 GYVSEFEKGTTQALGPATLEQVDRNIDVDKVDTESRAGEDANLQLEKQNSEIDSVSNSSL 1888
+ + TQALG A+ EQ + G +++++ Q D+
Sbjct: 4498 HLADQDDVADTQALGQASEEQAKA--------LDQNRGVESDVKPTDQEMLPDASDEPQA 4549
Query: 1889 LPKNEKRDQANMPVMEKSQDDGSVKPLGSANIDPESHLEDLISISRSYLGENTHKLSQLS 1948
LP+NE D M S +D + A I SH + S +++ E + QL
Sbjct: 4550 LPENELEDAMQMDHNGASTEDQAA----GAFIPGASHAQQNQSDAQAQPAE----IEQLD 4601
Query: 1949 VNDEELGKYHEPCDAPDHV-KDNATALWRRYELSTTKLSQELTEQLRLVLEPTVASKLQG 2007
D L H P +D A LW +YE +T LS LTEQLRL+L PT+A+KL+G
Sbjct: 4602 EVDSHLAAIHLSSTLPPLTPRDEAQRLWSKYESATNDLSLSLTEQLRLILAPTLATKLRG 4661
Query: 2008 YYKTGKRIHMKKVIQFIASYYRMDKIWLRRTRPNKRDYQVVIAVDDSHSMSESCCGDVAV 2067
Y+TGKR+++K++I +IAS Y+ DKIW+RR+ P+KR+YQ+++AVDDS SM ES G +A
Sbjct: 4662 DYRTGKRLNIKRIIPYIASQYKRDKIWMRRSVPSKRNYQIMLAVDDSKSMLESGSGQLAF 4721
Query: 2068 EALVTVCRAVSQLEMGSLAVASFGTKGNINLLHDFDSPFTAESGVKVSRIYTSLVFFFID 2127
E L V +++S LE G L V FG++ ++ + HDF PF++E+GV
Sbjct: 4722 ETLALVAKSLSMLEAGDLCVLGFGSEDHVRVAHDFGKPFSSEAGV--------------- 4766
Query: 2128 ISTVHLLNMLKGSDCSFLTEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLDAAVVKARL 2187
Q+ N +++Q T + + D + A K
Sbjct: 4767 ---------------------QVFQNFSYQQTGTNVRKLIADSIALFRE----ARFKQSP 4801
Query: 2188 PSGHNPLQQLVLIIADGRFHEKDNLKRCVREALASNRMVAFLLLDNSQ-ESIMDLMEASF 2246
G L QL LII+DG + + ++R VR+A M+ F+++D + SI+DL +ASF
Sbjct: 4802 AGGSADLWQLELIISDGICEDHETIRRLVRQAQEERIMIVFIIVDALKGNSILDLTQASF 4861
Query: 2247 EGG--------KMKFSKYMDSFPFPYYIVLRNIEALPRTLANLLRQ 2284
E K+K +Y++ FPFPYY+V+R++ LP LA L+Q
Sbjct: 4862 EPDNESGTGEMKLKMKRYLEGFPFPYYLVVRDVRELPAVLATALKQ 4907
Score = 71.6 bits (174), Expect = 3e-10
Identities = 67/309 (21%), Positives = 140/309 (44%), Gaps = 26/309 (8%)
Query: 591 SSKSANRYNFYKDSNAHEIEQMLKVLAPLRQQITSLLNEWEEQNDLQRFLDVIDMLLTLP 650
++ SA YNFY D N E +++L + ++ + + W + + V +
Sbjct: 3274 TTTSAKNYNFYTDQNPAEAKKLLILTRSIQARFVQIQQAWPDHAVPGDVISVCKEIYQFR 3333
Query: 651 SDIPLAKAFS---GLQFLLHKAQVMQENHSKFTFSNQLKSVFDLMSSWHKMELGSWPVLL 707
P+AK + L L+H+ Q++ +++ ++ + +L+ SW ++EL +W LL
Sbjct: 3334 HTEPVAKFLTKVEKLHSLVHEWQLVASR--EYSAASYYDELTNLIISWRRLELSTWAKLL 3391
Query: 708 DEVMDQYENNAK-------KSVLSSSIHYF*SINFPKSNFYFSYESCSLEDFIQTSSFGE 760
D D+ ++++ + I S S+ + +LE F +++ GE
Sbjct: 3392 DLEKDKCVQGVSSWWFIIFEALIRAPIQIAESGTTDLSD-HVQEVVGTLEQFTHSTTLGE 3450
Query: 761 FRKRLQLLYAFLGQNHTSACLKINSSNIVFFLHCWTLQLLSDGAVNILVQYVWILCAVLT 820
+ +RL+L+ F A L + + +L+ L N L Y AV
Sbjct: 3451 YSERLRLIKDF------RALLSLYVQDYP------SLKQLVFALDNFLQYYAQFEPAVSK 3498
Query: 821 NHIDASRKEILTELKDLVKLCRWEQDKSYSSIENLKKSRQKLKKLIKKHTDILQEPMDKL 880
ID R + ++K+ ++L W+ + E+ K+S KL KL++K+ ++L P++++
Sbjct: 3499 FLID-KRSSLEKDIKEQIQLASWKDTNIVALRESAKRSHVKLFKLVRKYREVLGLPVEQI 3557
Query: 881 IRDVLHKGS 889
+ + +G+
Sbjct: 3558 LSQDMPEGN 3566
Score = 62.4 bits (150), Expect = 2e-07
Identities = 90/435 (20%), Positives = 161/435 (36%), Gaps = 87/435 (20%)
Query: 1519 NEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQSGDDSCDEGDAQNDEAAAQNE 1578
+E+ T + K ESG + +G+G+ D S D GD ++ AQ E
Sbjct: 4069 HEESTEEGQSGKLESGTGLGEGEGAE---------------DISKDVGDDEDLSELAQQE 4113
Query: 1579 FDDEENGDDVNMDKEAAHSDATGLKPDEPDH--SSDMEIDLNANE--------------- 1621
E G+D++ K+A + D LK +E +H D E D + +E
Sbjct: 4114 -QQEGAGEDIDKSKDAVNMDQEDLKGEEGEHEEEEDGEKDESGDEGEEDDIDEEVGSVND 4172
Query: 1622 -DVDPIEEGDQEGHDDSAENGNQEDETCPPDEIMEEA----HTEVDVSSEKDDLGQEHQE 1676
DV ++E +G D + + +E E ++A E + E D G+E +E
Sbjct: 4173 LDVSAVDEKMWDGGHDEQQKETENEEGKGASEADQQAAAPEQKEGEKGEEGDKEGEEAEE 4232
Query: 1677 NDDMNSMDPKNDTSES-----SDVVNPQV---SNVDLASQSKSDLQTSGSENIASQSNLS 1728
D+ + +D E+ DV +PQ +DL + + D G ++
Sbjct: 4233 EDEEEEEEAPDDEGEAVGREDMDVTDPQAPEQETLDLPDEMQLDGDEKGMDD-------- 4284
Query: 1729 NSHHDFGNPAVTGGFPSSDMSEMDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEKQTNP 1788
DFG+ P + E D + + + LP E + +++ P
Sbjct: 4285 ---EDFGSDDGLDDLPDAPNDEQMDEKPDEN-----IEEEGPGDLPGEEEEINPDEEAPP 4336
Query: 1789 SRSTGDALDFRKEKINVSGDLPEDNIEHHGEMDDNNADEYGYVSEFEKGTTQALGPATLE 1848
+A + E P + E ++ DE ++++ + T A E
Sbjct: 4337 EEENANAAEGEDE-----AQAPAE------EPEETQQDE--FLAQRDDNETAGEEVAPSE 4383
Query: 1849 QVDRNIDVDKVDTESRAGEDANLQLEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKSQD 1908
V+ + ++ D G N Q + D ++ S+ PK + E+ +D
Sbjct: 4384 AVNGGLGAEQ-DQNQEKGASGNAQQQ------DGSTDPSVEPKQQTGAAKEGEENERHRD 4436
Query: 1909 DGSVKPLGSANIDPE 1923
G G +I+PE
Sbjct: 4437 AG-----GGDDINPE 4446
>UniRef100_Q6FIU8 Similar to sp|Q12019 Saccharomyces cerevisiae YLR106c [Candida
glabrata]
Length = 4880
Score = 297 bits (760), Expect = 3e-78
Identities = 254/893 (28%), Positives = 426/893 (47%), Gaps = 132/893 (14%)
Query: 1451 EEQEESKEVPGNDNTGIEMDQDFQADAVSLSE-DSSENEDCDGENEELESEMGPTGPD-S 1508
++ ++ +E DN ++M+ D + +S+ D+S++ D + + EEL+ E+ D +
Sbjct: 4053 QKDKDDREDDDEDNA-VDMEGDMAGELEDISDQDNSDDSDNESDEEELDEEINDIDDDDA 4111
Query: 1509 EAVGEKIWDQ------------NEDETPDDTGEKYESGPSVK--DGD-GSNKELRAKDDS 1553
AV +K+WD+ N+ E ++ E ++ + + +GD GSNKE +K+++
Sbjct: 4112 NAVDDKMWDEKVDDNLKEKETDNQIENQNNESEDVQAAENEQQENGDEGSNKEPDSKEEN 4171
Query: 1554 TSDQSGDDSCDEGDAQNDEAAAQNEFDDEENGDD---------VNMDKEAAHSDATGLKP 1604
DQ D GD Q + + D+EE+G++ VN +KE DA ++
Sbjct: 4172 NEDQQNDSENQNGDEQ------EQDLDNEESGEEDVGQQEDEVVNDEKEEQMFDAPEIET 4225
Query: 1605 DEPDHSSDMEIDLNANEDVDPIEEGDQ---EGHDDSAENGNQE----DETCPPDEIMEEA 1657
E DM++D D EE D G + +AE E DE D+ ME
Sbjct: 4226 MELPE--DMQLDSEEESKSDNEEEEDDMKDSGFESNAEEMEVEEDILDEKQNKDD-MEVD 4282
Query: 1658 HTEVDVSSEKDDLGQEHQENDDM---NSMDPKNDTS----ESSDVVNPQVSNVDLASQSK 1710
+ E + E+++L ++END+ N+ + ND E + PQ N + +
Sbjct: 4283 NLEEENIEEENNLSDANEENDNQEGENNDEDNNDVDMQDEEQTLQEEPQTENGETGTNI- 4341
Query: 1711 SDLQTSGSENIASQSNLSNSHHDFGNPAVTGGFPSSDMSEMDINMSDSSNTGGFSKTQPK 1770
D G EN ++ ++ + N G + E N+ DS T + Q K
Sbjct: 4342 DDEGAEGIENYLDNNDETSEANAEQNAGAKGAGADTKDDEDQENIGDSGMTNLEHQEQEK 4401
Query: 1771 SHLPQHEHSFSQEKQTNPSRSTGDAL-DFRKEKINVSGDLPEDNIEHHGEMDDNNADEYG 1829
++ + S+EK + GD+L ++ + ++ ++N E+ + + DE+
Sbjct: 4402 DS--ENHNDSSREKANEVLKELGDSLKEYHNRRQEINNPSNDENKENENKANQR-PDEFE 4458
Query: 1830 YVSEFEKGT-TQALGPATLEQVDRNIDVDKVDTESRAGEDANLQLEKQNSEIDSVSNSSL 1888
++ T TQALG A E+ + K+D + +D + + EK +S+ID+ ++L
Sbjct: 4459 HLDGANTETDTQALGGANQEEAN------KIDDDLAINDDLDEE-EKIDSDIDTDDAANL 4511
Query: 1889 LPKNEKRDQANMPVMEKSQDDGSVKPLGSANIDPESHLEDLISISRSYLGENT------- 1941
NE +++ + Q D K G+ S ++DL SI + EN
Sbjct: 4512 ESHNEIKEELEEDLNTDIQKDTDSKSQGAF----ASTMKDL-SIEDKEIYENDGLFKRED 4566
Query: 1942 --HKLSQLSVNDEELGKYHEPCDAPDHVKDNATALWRRYELSTTKLSQELTEQLRLVLEP 1999
++L QL ++ D P + LWR+ E+ T +LS L EQLRL+LEP
Sbjct: 4567 YENELDQLMDEIDKETNLKAEIDKPQRDLTESRELWRKSEIETVELSARLGEQLRLILEP 4626
Query: 2000 TVASKLQGYYKTGKRIHMKKVIQFIASYYRMDKIWLRRTRPNKRDYQVVIAVDDSHSMSE 2059
T+A+KL+G YKTGKR++MK++I +IAS YR DKIWLRRT+P+KR YQ+++A+D+S SMSE
Sbjct: 4627 TLATKLRGDYKTGKRLNMKRIIPYIASQYRKDKIWLRRTKPSKRQYQIMLALDNSKSMSE 4686
Query: 2060 SCCGDVAVEALVTVCRAVSQLEMGSLAVASFGTKGNINLLHDFDSPFTAESGVKVSRIYT 2119
S +A +L V + +SQLE G L++ FG +H FD F+ +SG KV + +
Sbjct: 4687 SKSAQLAFNSLCLVSKTLSQLESGGLSIVRFGE--YTKEVHSFDQNFSNDSGSKVFQWF- 4743
Query: 2120 SLVFFFIDISTVHLLNMLKGSDCSFLTEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLD 2179
F+++ T V + +K
Sbjct: 4744 -----------------------------------NFQEDKTDVKRLVGESIKIFE---- 4764
Query: 2180 AAVVKARLPSGHNPLQQLVLIIADGRFHEKDNLKRCVREALASNRMVAFLLLDN---SQE 2236
+AR S N QL ++I+DG + D ++R VR A M+ F+++DN S E
Sbjct: 4765 ----RARAYS-DNDQWQLEIVISDGLCEDHDTVERLVRRARDKKIMLVFVIIDNLGQSNE 4819
Query: 2237 SIMDLMEASFEGG-----KMKFSKYMDSFPFPYYIVLRNIEALPRTLANLLRQ 2284
SIMD+ + + ++K +KY+D+FPF +Y+V+ +I LP LA +LRQ
Sbjct: 4820 SIMDMSQVKYVPDSSGNLQLKITKYLDTFPFEFYVVVHDIVELPEMLALILRQ 4872
Score = 88.2 bits (217), Expect = 3e-15
Identities = 143/769 (18%), Positives = 299/769 (38%), Gaps = 121/769 (15%)
Query: 123 NYTIGCAWAHIGALRIHLLLSYNEVDPVMKYYCKYTQLEETISSLELEIQVRKECGYLSG 182
++ + W + G I L DP ++ Y +Y L+ E + G+
Sbjct: 2848 SFALASCWIYFGITLIELFCPDTAFDPAIENYVQYDLFRSHRDFLQAE-----KSGWAKF 2902
Query: 183 QFLTVEADKRKAERLEKLQAELRKLQRKIVFRSESWKYKKLMNECDEFLKHIASLEVLVG 242
+ +T E L + E ++ +V+R+ L +E + FL S + +
Sbjct: 2903 RMVTSGVTPIYNELLAQSIEEPSAPEKPLVYRTNE-AVDDLFDEWNAFLLSSLSQDHIND 2961
Query: 243 NVEAEDLQQVID-RTHSWQETAMCFINRLTDEYTAYNDIIQPIQVAVYEMKFGLSLVLSS 301
V+A L+ I R S Q + F+ R+ + ++D+ ++ +KFG ++
Sbjct: 2962 LVQAGKLKHSISSRLDSLQVNSSKFVERVKSGFKMFSDLNDIFAGYIFAIKFGFDIMKQK 3021
Query: 302 FLEKEYLRKVGHENINLVTDMIYILMRFPRAASWKFISVEDVGVDLHSSYKLDFGTDFYL 361
L ++N++ T ++ + ++V + V H +
Sbjct: 3022 LL---------NDNLHQGTTRLWAVN--------PLLTVSEYSVKQH-----------FK 3053
Query: 362 NMGLIERLITLSSGVSADKKVSAMRCRASIYWNILVQIAYSIANAKIIDRESYMLLHKIF 421
NM ++ + + ++ AD+ + + + Y + +++D + H+
Sbjct: 3054 NMFVMLQRAS-ANNYDADRTLL----------HFVRLFRYFKQSDELLD-----IFHESL 3097
Query: 422 DEFASLWMSMKVYAKSKSDHDAQQFKFKPRAFQIESIMELEIPALANSSATEAFSDWKEF 481
+ W K+ ++ K + A+ FK+ + E E F D+
Sbjct: 3098 HTLYARWSMRKMQSEKKQEEQAKTFKYTDESDDFEREFR------------EMFPDYD-- 3143
Query: 482 SYEEKSADNMESSEECEILDEEWKHLEESILDNVVLIHSQLFGSGDLVQAPGIFEISDED 541
D + SE+ + DEE L + + + LF S + + + I++
Sbjct: 3144 -------DELNLSEDIKSQDEETVDLYHQL----TIEYMNLFSSDEQLSLNDV--ITEGT 3190
Query: 542 RLHSFSESYKLGINLIKGAHSSNLASLDAKLIPEHLFYLSIDYRRKFHSSSKSANR-YNF 600
++ S S L L G + PE L ++ +K + K+ N+ ++
Sbjct: 3191 KISSLDNS--LSAQLTSGI-----------VTPETLLSVANILAQKINGFDKTENKSFSI 3237
Query: 601 YKDSNAHEIEQMLKVLAPLRQQITSLLNEWEEQNDLQRFLDVIDMLLTLPSDIPLAKAFS 660
+KD + E ++ + + L ++ LLN+W E LQ L+ D +A+
Sbjct: 3238 FKDFSIPESKKAARSILTLLGKVNELLNQWPENATLQDLFRTCHEFLSFTLDTTIARQLQ 3297
Query: 661 GLQFLLHKAQVMQENHSKFTFS--NQLKSVFDLMSSWHKMELGSWPVLLDEVMDQYENNA 718
L+ ++ E ++ T S + + + + + SW +MEL SW E++ + A
Sbjct: 3298 KLE-QIYTILTEWEKYASSTVSLNDYITEIVNTLVSWRRMELRSW----SELLLNEDKQA 3352
Query: 719 KKSVLSSSIHYF*SINFP-KSNFYFSYESC-----SLEDFIQTSSFGEFRKRLQLLYAFL 772
++S+ + + +I P +SN E +L F S+ GE+ R+ L+ +F
Sbjct: 3353 QRSISKWWFYLYETIILPTESNMDGENEKQYKLLQALNVFFSESTIGEYDHRINLVISFK 3412
Query: 773 GQNHTSACLKINSSNIVFFLHCWTLQLLSDGAVNILVQYVWILCAVLTNHIDASRKEILT 832
S K + N + NI++ Y V + I +RK +
Sbjct: 3413 EHLLNSFPNKEQTINAL---------------TNIILYYKQFQEKV-QDVIKTTRKTLDK 3456
Query: 833 ELKDLVKLCRWEQDKSYSSIENLKKSRQKLKKLIKKHTDILQEPMDKLI 881
++KD++ L W+ + ++ KKS L K+++K+ +++ + LI
Sbjct: 3457 DMKDIILLASWKDVNIDALKQSSKKSHNNLYKIVRKYRNVISGKVTDLI 3505
Score = 68.2 bits (165), Expect = 3e-09
Identities = 89/443 (20%), Positives = 158/443 (35%), Gaps = 50/443 (11%)
Query: 1540 GDGSNKELRAKDDSTSDQSGDDSCDEGDAQNDEAAAQNEFDDEENGDDVNMDKEAAHSDA 1599
GDG E ++ D + +D+ Q D+ E DDE+N D+ D D
Sbjct: 4024 GDGEGAENKSNDIDQDEDLTEDAQTSNQDQKDK--DDREDDDEDNAVDMEGDMAGELEDI 4081
Query: 1600 TGL-KPDEPDHSSDMEIDLNANEDVDPIEEGDQEGHDD------------------SAEN 1640
+ D+ D+ SD E +E+++ I++ D DD EN
Sbjct: 4082 SDQDNSDDSDNESDEE---ELDEEINDIDDDDANAVDDKMWDEKVDDNLKEKETDNQIEN 4138
Query: 1641 GNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEHQENDDMNSMDPKNDTSESSDVVNPQV 1700
N E E E E D S K+ +E D N + +N + D+ N +
Sbjct: 4139 QNNESEDVQAAE--NEQQENGDEGSNKEPDSKEENNEDQQNDSENQNGDEQEQDLDNEES 4196
Query: 1701 SNVDLASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAVTGGFPSSDMSEMDINMSDSSN 1760
D+ Q + E + + + SD E + +M DS
Sbjct: 4197 GEEDVGQQEDEVVNDEKEEQMFDAPEIETMELPEDMQLDSEEESKSDNEEEEDDMKDS-- 4254
Query: 1761 TGGFSKTQPKSHLPQHEHSFSQEKQTNPSRSTGDALDFRKEKINVSGDLPEDNIEHHGEM 1820
GF + + E EKQ + + E+ N D E+N GE
Sbjct: 4255 --GFESNAEEMEV---EEDILDEKQNKDDMEVDNLEEENIEEENNLSDANEENDNQEGEN 4309
Query: 1821 DDNNADEYGYVSE---------FEKGTT----QALGPATLEQ-VDRNIDVDKVDTESRA- 1865
+D + ++ E E G T G +E +D N + + + E A
Sbjct: 4310 NDEDNNDVDMQDEEQTLQEEPQTENGETGTNIDDEGAEGIENYLDNNDETSEANAEQNAG 4369
Query: 1866 --GEDANLQLEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKSQDDGSVKPLGSANIDPE 1923
G A+ + ++ I ++L + +++D N + + + +K LG + +
Sbjct: 4370 AKGAGADTKDDEDQENIGDSGMTNLEHQEQEKDSENHNDSSREKANEVLKELGDSLKEYH 4429
Query: 1924 SHLEDLISISRSYLGENTHKLSQ 1946
+ +++ + S EN +K +Q
Sbjct: 4430 NRRQEINNPSNDENKENENKANQ 4452
Score = 53.9 bits (128), Expect = 6e-05
Identities = 74/349 (21%), Positives = 138/349 (39%), Gaps = 49/349 (14%)
Query: 1626 IEEGDQEGHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEHQENDDMNSMDP 1685
+ EG G + AEN + + + +++ E+A T +KDD + D+ N++D
Sbjct: 4017 LHEGTGLGDGEGAENKSNDIDQ--DEDLTEDAQTSNQDQKDKDDREDD----DEDNAVDM 4070
Query: 1686 KNDTSESSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAVTGGFPS 1745
+ D + + D++ Q SD S+N + + L +D +
Sbjct: 4071 EGDMAGELE---------DISDQDNSD----DSDNESDEEELDEEINDIDD--------- 4108
Query: 1746 SDMSEMDINMSDSSNTGGFSKTQPKSHLP-QHEHSFSQEKQTNPSRSTGDALDFRKEKIN 1804
D + +D M D + + + + Q+ S + N + GD E N
Sbjct: 4109 DDANAVDDKMWDEKVDDNLKEKETDNQIENQNNESEDVQAAENEQQENGD------EGSN 4162
Query: 1805 VSGDLPEDNIE-HHGEMDDNNADEYGYVSEFEKGTTQALGPATLEQV-----DRNIDVDK 1858
D E+N E + ++ N DE + E+ + +G E V ++ D +
Sbjct: 4163 KEPDSKEENNEDQQNDSENQNGDEQEQDLDNEESGEEDVGQQEDEVVNDEKEEQMFDAPE 4222
Query: 1859 VDTESRAGEDANLQLEKQ----NSEIDSVSNSSLLPKNEKRDQANMPVMEKSQ--DDGSV 1912
++T ED L E++ N E + S N + + ++++ Q DD V
Sbjct: 4223 IET-MELPEDMQLDSEEESKSDNEEEEDDMKDSGFESNAEEMEVEEDILDEKQNKDDMEV 4281
Query: 1913 KPLGSANIDPESHLEDLISISRSYLGENTHK-LSQLSVNDEELGKYHEP 1960
L NI+ E++L D + + GEN + + + + DEE EP
Sbjct: 4282 DNLEEENIEEENNLSDANEENDNQEGENNDEDNNDVDMQDEEQTLQEEP 4330
Score = 50.1 bits (118), Expect = 8e-04
Identities = 69/402 (17%), Positives = 151/402 (37%), Gaps = 59/402 (14%)
Query: 1555 SDQSGDDSCDEGDAQNDEAAAQNEFDDEENGDDVNMDKEAAHSDATGLKPDEPDHSSDME 1614
S+++ D++ EG D A+N+ +D + +D+ D + ++ D
Sbjct: 4009 SEETYDENLHEGTGLGDGEGAENKSNDIDQDEDLTEDAQTSNQDQ--------------- 4053
Query: 1615 IDLNANEDVDPIEEGDQEGHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEH 1674
++ D DD + E + E + + D +E D+ +
Sbjct: 4054 ------------KDKDDREDDDEDNAVDMEGDMAGELEDISDQDNSDDSDNESDEEELDE 4101
Query: 1675 Q----ENDDMNSMDPKNDTSESSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNS 1730
+ ++DD N++D K + D + + ++ + +Q+ +EN ++ S
Sbjct: 4102 EINDIDDDDANAVDDKMWDEKVDDNLKEKETDNQIENQNNESEDVQAAENEQQENGDEGS 4161
Query: 1731 HHDFGNPAVTGGFPSSDMSEMDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEKQTNPSR 1790
+ + P S + +DS N G + Q + E Q++ +
Sbjct: 4162 NKE----------PDSKEENNEDQQNDSENQNGDEQEQDLDNEESGEEDVGQQEDEVVND 4211
Query: 1791 STGDALDFRKEKINVSGDLPE------------DNIEHHGEMDDNNADEYGYVSEFEKGT 1838
+ + F +I +LPE DN E +M D+ + E E+
Sbjct: 4212 EKEEQM-FDAPEIETM-ELPEDMQLDSEEESKSDNEEEEDDMKDSGFESNAEEMEVEEDI 4269
Query: 1839 TQALGPATLEQVDRNIDVDKVDTESRAGEDANLQLEKQNSEIDSVSNSSLLPKNEKRDQA 1898
+VD N++ + ++ E+ DAN + + Q E + N+ + ++E++
Sbjct: 4270 LDEKQNKDDMEVD-NLEEENIEEENNL-SDANEENDNQEGENNDEDNNDVDMQDEEQTLQ 4327
Query: 1899 NMPVMEKSQDDGSVKPLGSANIDPESHLEDLISISRSYLGEN 1940
P E + ++ G+ I E++L++ S + +N
Sbjct: 4328 EEPQTENGETGTNIDDEGAEGI--ENYLDNNDETSEANAEQN 4367
>UniRef100_Q5RII8 Novel protein similar to human MDN1, midasin homolog [Brachydanio
rerio]
Length = 2197
Score = 294 bits (752), Expect = 3e-77
Identities = 262/927 (28%), Positives = 441/927 (47%), Gaps = 160/927 (17%)
Query: 1450 KEEQEESKEVPGNDNTGIEMDQDFQADAVSLS--EDSSENEDCDGENEELESEMGPTGP- 1506
K+E+E+ K+ ++ IEM +DF + E + ED D E+EEL+ +MG G
Sbjct: 1329 KDEEEQDKQDIKEEDNAIEMSEDFDGKMHDGTDREPGEDEEDSDKEDEELDKKMGDLGDG 1388
Query: 1507 DSEAVGEKIW--DQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDST-SDQSGDDSC 1563
++ + E++W D ++++ DD+ ++ ESGP + G+ EL AKDD+T + +S D
Sbjct: 1389 QTDTLDERMWGDDDDDEDNNDDSDKEEESGPGMDQGES---ELVAKDDNTDAGESNKDKN 1445
Query: 1564 DEGDAQNDEAAAQN--------EFDDEENG------------------DDVNMDKEAAHS 1597
+ D DE + EFD+ E +++N+D++
Sbjct: 1446 QDKDLPKDEEEKEKIHEQVDEREFDENEVDPYHGKQEKKAEPEAMELPEELNLDEDGKDE 1505
Query: 1598 DATGLKPDEPDHSSD--MEIDLNANEDVDPIEEGDQEGHDDSAENGNQEDETCPPD--EI 1653
+ + P D ME+D ED EEG E D+ + G QE+E D E
Sbjct: 1506 EGEEANEENPFDIDDKLMEVDEKTGEDKGEPEEGGDEMTDEQQQEG-QEEEHGEEDNTEE 1564
Query: 1654 MEEAHTEVDVSSEKDDLGQEHQENDDMNS-------------------MDPKNDTSESSD 1694
EEA D E D+ G+ +E+D+ +PK + D
Sbjct: 1565 KEEAEKSEDQDPEMDERGENEEEDDNKEKNKGQEEGREEDKSIPADQGQEPKKEEDGDED 1624
Query: 1695 VVNPQVSNVDLASQSK--SDLQTSGSENIASQS--NLSNSHHDFGNPAVTGGFPSSDMSE 1750
P +D A + + SD QT G EN+ S + L+ + + G ++D S+
Sbjct: 1625 DEAP----LDSAERKEHASDGQT-GEENVQSDTAVELAGAASEKDQAKEEDGSGAADASQ 1679
Query: 1751 MDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEK-QTNPSRSTGDALDFRKEKINVSGDL 1809
S+ ++ ++ + ++ SF ++ Q + RS GD + +++ D
Sbjct: 1680 -----SEGHDSKLMARMSSQKQRQKNTQSFKRKPGQADNERSMGDYNERVNKRLRTV-DK 1733
Query: 1810 PEDNIEHHGEMD-DNNADEYGYVSEF-EKGTTQALGPATLEQVD-RNIDVDKVDTESRAG 1866
E + + D +D Y ++ + E+ Q A+ EQ + ++ D E
Sbjct: 1734 TEQKTQDQTQPDTQQESDLYEHIKQGDERYDAQTYDVASKEQQKPTGVKQEEEDEE---- 1789
Query: 1867 EDANLQLEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKSQDDGSVKPLGSANIDPESHL 1926
+D +++E++ ++ +V L P+ ++A+ +K D G ++ A + L
Sbjct: 1790 DDIAMEVEEEK-DLQAVEAQELKPEKLNDNKAS----QKGLDCGDLEAQKQAIEEEMEKL 1844
Query: 1927 EDLISISRSYLGENT-----HKLSQLSV--------NDEELGKYHE-------PCDAPDH 1966
E SI+ + E + H + +L + N EEL + E H
Sbjct: 1845 ETQRSINEEEMKERSDESTIHTVPELLMETQKATLMNPEELRREMELQLEAWQRQTLGSH 1904
Query: 1967 VKDNATA-LWRRYELSTTKLSQELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKVIQFIA 2025
+++A A LW +Y+ T+ LSQ+L EQLRLVLEPT A+KL+G ++TGKR++M+KVI +IA
Sbjct: 1905 EEESAAAALWHQYQTLTSPLSQQLCEQLRLVLEPTQAAKLRGDFRTGKRLNMRKVIPYIA 1964
Query: 2026 SYYRMDKIWLRRTRPNKRDYQVVIAVDDSHSMSESCCGDVAVEALVTVCRAVSQLEMGSL 2085
S +R DKIWLRRT+P+KR+YQ+ +AVDDS SM ++ +A EA+ + A++ LE+G +
Sbjct: 1965 SQFRKDKIWLRRTKPSKRNYQICLAVDDSSSMVDNHTKQLAFEAVSVIVNALTLLEVGQV 2024
Query: 2086 AVASFGTKGNINLLHDFDSPFTAESGVKVSRIYTSLVFFFIDISTVHLLNMLKGSDCSFL 2145
+V SFG + LLH F F ++G K+ R+
Sbjct: 2025 SVCSFGE--TVQLLHPFHQQFNDQTGAKILRL---------------------------- 2054
Query: 2146 TEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLDAAVVKARLPSGHN-PLQQLVLIIADG 2204
F+Q+ T + L+ TN AA K ++P N QL+LI++DG
Sbjct: 2055 --------CQFQQKKT----RIAQFLETSTNMFMAA--KQQIPGATNTETSQLLLIVSDG 2100
Query: 2205 R---FHEKDNLKRCVREALASNRMVAFLLLD--NSQESIMDLMEASFEG-GKM-KFSKYM 2257
R K+ + V+ A ++N V F++LD NS++SI+D+ F+G G++ + YM
Sbjct: 2101 RGLFLEGKERVATAVQAARSANVFVIFVVLDNPNSRDSILDIKVPIFKGPGELPEIRSYM 2160
Query: 2258 DSFPFPYYIVLRNIEALPRTLANLLRQ 2284
+ FPFP+Y++LRN+ LP TL++ LRQ
Sbjct: 2161 EEFPFPFYVILRNVNGLPETLSDALRQ 2187
Score = 142 bits (358), Expect = 1e-31
Identities = 167/758 (22%), Positives = 300/758 (39%), Gaps = 101/758 (13%)
Query: 196 RLEKLQAELRKLQRKIVFRSESWKYKKLMNECDEFL-------------KHIASLEVLVG 242
R+++++ ++ +L RK +R +Y +L E +L H+ G
Sbjct: 5 RMQQVKEQICELSRKQAYRPPEPQYGRLYQELQHYLCSIGQPAAVGDLLSHLLKALQAPG 64
Query: 243 NVEAEDLQQVIDRTHSWQETAMCFINRLTDEYTAYNDIIQPIQVAVYEMKFGLSLVLSSF 302
+Q ++ WQ + F RL +E+ Y D++ P++ A+ +++ G+ L+ S
Sbjct: 65 PKSKLGVQGLLKEEAVWQASQHRFSQRLLEEFPLYPDVVVPLRAAILQVQHGMRLLAS-- 122
Query: 303 LEKEYLRKVGHENINLVTDMIYILMRFPRAASWKFISVEDVGVDLHSSYKLDFGTDFYLN 362
+ + ++LV+ M+ FP + ++ D+ +
Sbjct: 123 -QVSFSTTAQPGLVHLVSTML----TFPCPVASSDLAC----------------ADYLCS 161
Query: 363 MGLIERLITLSSGVSADKKVSAMRCRASIYWNILVQIAYSIANAKIIDRESYMLLHKIFD 422
+ L TL + A + + A + N L+ I +A + E+ L +
Sbjct: 162 RECLRTLKTLGKQLPATEVSRVIPDHAVLLLNALLYIQSHTLSAGQLSAEAQKLFRHVCQ 221
Query: 423 EFASLWMSMKVYAKSKSDHDAQQFKFKPRAFQIESIMELEIPALANSSATEAFSDWKEFS 482
+ W + A+ K +A ++ + R + + S D+ + +
Sbjct: 222 AIVNEWDEQEKRAREKEQMEASLYRSRSRLHGTGLTEDQQEEREFRRSFPSYHKDFADIT 281
Query: 483 YEEKSADN---MESSEECEILDE--EWKHLEESILDNVVLIHSQLFGSGDLVQAPGIFEI 537
E S D +E ++ ++ E E L S + VV +H +L L A ++
Sbjct: 282 -SEPSLDQPIIIEDDDDADMKAESSETSSLLISNMSRVVQVHQRLC----LSFARSLWYH 336
Query: 538 SD------EDRLHSFSESYKLGINLIKGAHSSNLASLDAKLIPEHLFYLSIDYRRKFHSS 591
S+ +D + + SY++ LI + +++KL+ L LS + S
Sbjct: 337 SEPPTNHAKDHISALVSSYQITAPLIARFYHLMDCEVNSKLMGSQLL-LSTLLQNTVSGS 395
Query: 592 SKSANR-------YNFYKDSNAHEIEQMLKVLAPLRQQITSLLNEWEEQNDLQRFLDVID 644
SA Y+FY++ N + L L L + + LN+W E L + + VI+
Sbjct: 396 GGSAGLILQNDGPYDFYREPNMSQARLCLPALEQLSKAVRQRLNDWPEHPALVQIIMVIE 455
Query: 645 MLLTLPSDIPLAKAFSGLQFLLHKAQVMQENHSK-FTFSNQLKSVFDLMSSWHKMELGSW 703
+L PLAK +GL+ LL KAQ + N S+ + N+L+ V L+ W K+EL W
Sbjct: 456 RILAFSLSSPLAKFLNGLEILLSKAQDWENNASRAVSLRNELEVVTQLIIQWRKLELNCW 515
Query: 704 PVLLDEVMDQYENNAKKSVLS--SSIHYF*SINFPKS-------NFYFSYESCSLEDFIQ 754
LD + ++ N+ K LS I + S N S S SL+ FI+
Sbjct: 516 SSSLDNALKRHAENSTKHWLSIYQLIEKYLQEQKTNSRHDDGVENLSLSSVSSSLQAFIE 575
Query: 755 TSSFGEFRKRLQLLYAFLGQNHTSACLKINSSNIVFFLHCWTLQLLSDGAVNILVQYVWI 814
S+ GEF RL +L F HC L + L +W
Sbjct: 576 GSTLGEFSVRLSMLLGF---------------------HCHILLAPKQEGHDSLCSLLWN 614
Query: 815 L-------CAVLTNHIDASRKEILTELKDLVKLCRWEQDKSYSSIENLKKSRQKLKKLIK 867
L + I R + ELKD VK+ +W +S +++K+ + L K +K
Sbjct: 615 LYKYYSQFSPSIQTKITHLRSPLEKELKDFVKISKWNDVSFWSIKHSVEKTHRTLFKFVK 674
Query: 868 KHTDILQEPMDKLIRDVLHKGSISGVSDLPLFSDENRL 905
K L+EP + + +GS S + D+ +E L
Sbjct: 675 KFEAALKEPCAPCL---VEQGSSSSMDDVDSQPEETPL 709
Score = 57.8 bits (138), Expect = 4e-06
Identities = 87/450 (19%), Positives = 175/450 (38%), Gaps = 43/450 (9%)
Query: 1531 YESGPSVKDGDGSNKELRAKDDSTSDQSGDDSCDEGDAQNDEAAAQNEFDDEENGDDVNM 1590
YE G + +G+G D ++ +D+ EG +++E + + +E+N +++
Sbjct: 1295 YEGG-GIGEGEGVKD---VSDKIENEDQVEDTFQEGKDKDEEEQDKQDIKEEDNAIEMSE 1350
Query: 1591 DKEAAHSDATGLKPDEPDHSSDM---EIDLNANE----DVDPIEE---GDQEGHDDSAEN 1640
D + D T +P E + SD E+D + D ++E GD + +D+ ++
Sbjct: 1351 DFDGKMHDGTDREPGEDEEDSDKEDEELDKKMGDLGDGQTDTLDERMWGDDDDDEDNNDD 1410
Query: 1641 GNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQ----EHQENDDMNSMDPKNDTSESSDVV 1696
++E+E+ P M++ +E+ + D G+ ++Q+ D + K E D
Sbjct: 1411 SDKEEESGPG---MDQGESELVAKDDNTDAGESNKDKNQDKDLPKDEEEKEKIHEQVDER 1467
Query: 1697 NPQVSNVDLASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAVTGGFPSSDMSEMDINMS 1756
+ VD + + + + NL D P ++D +
Sbjct: 1468 EFDENEVDPYHGKQEKKAEPEAMELPEELNLDEDGKDEEGEEANEENP----FDIDDKLM 1523
Query: 1757 DSSNTGGFSKTQPK---SHLPQHEHSFSQEKQTNPSRSTGDALDFRK-EKINVSGDLPED 1812
+ G K +P+ + + QE++ +T + + K E + D +
Sbjct: 1524 EVDEKTGEDKGEPEEGGDEMTDEQQQEGQEEEHGEEDNTEEKEEAEKSEDQDPEMDERGE 1583
Query: 1813 NIEHHGEMDDNNADEYGYVSEFEKGTTQALGPATLEQVDRNIDVDKVDTESRAGEDANLQ 1872
N E + N E G + Q P E D + D +D+ R ++ Q
Sbjct: 1584 NEEEDDNKEKNKGQEEGREEDKSIPADQGQEPKKEEDGDED-DEAPLDSAERKEHASDGQ 1642
Query: 1873 LEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKSQDDGSVKPLGSANIDPESHLEDLISI 1932
++N + D+ L ++DQA ++DGS S + +S L +S
Sbjct: 1643 TGEENVQSDTA--VELAGAASEKDQA-------KEEDGSGAADASQSEGHDSKLMARMS- 1692
Query: 1933 SRSYLGENTHKLSQ---LSVNDEELGKYHE 1959
S+ +NT + + N+ +G Y+E
Sbjct: 1693 SQKQRQKNTQSFKRKPGQADNERSMGDYNE 1722
Score = 48.1 bits (113), Expect = 0.003
Identities = 62/290 (21%), Positives = 120/290 (41%), Gaps = 30/290 (10%)
Query: 1447 MQKKEEQEESKEVPGN-DNTGIEMDQDFQADAVSLSEDSSENEDCD-------GENEELE 1498
M +++QE +E G DNT + + + D ++ ENE+ D G+ E E
Sbjct: 1543 MTDEQQQEGQEEEHGEEDNTEEKEEAEKSEDQDPEMDERGENEEEDDNKEKNKGQEEGRE 1602
Query: 1499 SEMG-PTGPDSEAVGEKIWDQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQ 1557
+ P E E+ D+ +DE P D+ E+ E DG E + D+ +
Sbjct: 1603 EDKSIPADQGQEPKKEEDGDE-DDEAPLDSAERKEHA-----SDGQTGEENVQSDTAVEL 1656
Query: 1558 SG----DDSCDEGDAQNDEAAAQNEFDDEENGDDVNMDKE-AAHSDATGLKPDEPDHSSD 1612
+G D E D A+Q+E D + ++ K+ ++ + KP + D+
Sbjct: 1657 AGAASEKDQAKEEDGSGAADASQSEGHDSKLMARMSSQKQRQKNTQSFKRKPGQADNERS 1716
Query: 1613 M-EIDLNANEDVDPIEEGDQEGHDDSAENGNQEDETC----PPDEIMEEAHTEVDVSSEK 1667
M + + N+ + +++ +Q+ D + + QE + DE + +V ++
Sbjct: 1717 MGDYNERVNKRLRTVDKTEQKTQDQTQPDTQQESDLYEHIKQGDERYDAQTYDVASKEQQ 1776
Query: 1668 DDLGQEHQENDD-----MNSMDPKNDTSESSDVVNPQVSNVDLASQSKSD 1712
G + +E D+ M + K+ + + + P+ N + ASQ D
Sbjct: 1777 KPTGVKQEEEDEEDDIAMEVEEEKDLQAVEAQELKPEKLNDNKASQKGLD 1826
>UniRef100_Q12019 Midasin [Saccharomyces cerevisiae]
Length = 4910
Score = 290 bits (743), Expect = 3e-76
Identities = 236/889 (26%), Positives = 413/889 (45%), Gaps = 128/889 (14%)
Query: 1448 QKKEEQEESKEVPGNDNTGIEMDQDFQADAVSLSE-DSSENEDCDGENEELESEMGPTGP 1506
+ KE+Q++ + N++ +EM+ D + LS + +++ED D E EEL+ E+
Sbjct: 4090 ENKEQQDKDERDDENEDDAVEMEGDMAGELEDLSNGEENDDEDTDSEEEELDEEIDDLNE 4149
Query: 1507 DS-EAVGEKIWDQ--NEDETPDDTGEKYESGPSVKDGDGSNKELRAKD-------DSTSD 1556
D A+ +K+WD +++ DT + + +D + + + +D D +
Sbjct: 4150 DDPNAIDDKMWDDKASDNSKEKDTDQNLDGKNQEEDVQAAENDEQQRDNKEGGDEDPNAP 4209
Query: 1557 QSGDDSCDE---GDAQNDEAAAQNEFDDEENGD---------------DVNMDKEAAHSD 1598
+ GD+ + + +ND ++E DEE D D+N+D E SD
Sbjct: 4210 EDGDEEIENDENAEEENDVGEQEDEVKDEEGEDLEANVPEIETLDLPEDMNLDSEHEESD 4269
Query: 1599 ATGLKPDEPDHSSDMEIDLN----ANEDVDPIEEGDQEGHDDSAENGNQEDETCPPDEIM 1654
++ D S M DLN NED + +E E +++ E G +ED +
Sbjct: 4270 ------EDVDMSDGMPDDLNKEEVGNEDEEVKQESGIESDNENDEPGPEEDAGETETALD 4323
Query: 1655 EEAHTEVDVSSEKDDLGQEHQENDDMNSMDPKNDTSESSDVVNPQVSNVDLASQSKSDLQ 1714
EE E DV D+ G+E +EN + + S + Q + ++ + +
Sbjct: 4324 EEEGAEEDVDMTNDE-GKEDEENGP-------EEQAMSDEEELKQDAAMEENKEKGGEQN 4375
Query: 1715 TSGSENIASQSNLSNSHHDFGNPAVTG----GFPSSDMSEMDINMSDSSNTGGFSKTQPK 1770
T G + + +++ + + +G G ++D E D + GG TQ
Sbjct: 4376 TEGLDGVEEKADTEDIDQEAAVQQDSGSKGAGADATDTQEQD-------DVGGSGTTQNT 4428
Query: 1771 SHLPQHE----HSFSQEKQTNPSRSTGDAL-DFRKEKINVSGDLPEDNIEHHGEMDDNNA 1825
Q + + S+E+ T + GD++ ++ + + ++ + + E ++
Sbjct: 4429 YEEDQEDVTKNNEESREEATAALKQLGDSMKEYHRRRQDIKEAQTNGEEDENLEKNNERP 4488
Query: 1826 DEYGYVSEFEKGT-TQALGPATLEQVDRNIDVDKVDTESRAGEDANLQ--LEKQNSEIDS 1882
DE+ +V T TQALG AT +Q+ + ID D + R ++ + + +E + E
Sbjct: 4489 DEFEHVEGANTETDTQALGSATQDQL-QTIDEDMAIDDDREEQEVDQKELVEDADDEKMD 4547
Query: 1883 VSNSSLLPKNEKRDQANMPVMEKSQDDGSVKPLGSANIDPESHLEDLISISRSYLGENTH 1942
+ +L + D N +KS G K E +L + S E+
Sbjct: 4548 IDEEEMLSDIDAHDANNDVDSKKSGFIGKRK-------SEEDFENELSNEHFSADQEDDS 4600
Query: 1943 KLSQLSVNDEELGKYHEPCDAPDHVKDNATALWRRYELSTTKLSQELTEQLRLVLEPTVA 2002
++ L N E+ P+ + + LW + E+ST L L EQLRL+LEPT+A
Sbjct: 4601 EIQSLIENIEDNPPDASASLTPERSLEESRELWHKSEISTADLVSRLGEQLRLILEPTLA 4660
Query: 2003 SKLQGYYKTGKRIHMKKVIQFIASYYRMDKIWLRRTRPNKRDYQVVIAVDDSHSMSESCC 2062
+KL+G YKTGKR++MK++I +IAS +R DKIWLRRT+P+KR YQ++IA+DDS SMSES C
Sbjct: 4661 TKLKGDYKTGKRLNMKRIIPYIASQFRKDKIWLRRTKPSKRQYQIMIALDDSKSMSESKC 4720
Query: 2063 GDVAVEALVTVCRAVSQLEMGSLAVASFGTKGNINLLHDFDSPFTAESGVKVSRIYTSLV 2122
+A ++L V + ++QLE G L++ FG NI +H FD F+ ESG + + +
Sbjct: 4721 VKLAFDSLCLVSKTLTQLEAGGLSIVKFGE--NIKEVHSFDQQFSNESGARAFQWF---- 4774
Query: 2123 FFFIDISTVHLLNMLKGSDCSFLTEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLDAAV 2182
F++ T + V + K + + A V
Sbjct: 4775 --------------------------------GFQETKTDVKKLVAESTK-IFERARAMV 4801
Query: 2183 VKARLPSGHNPLQQLVLIIADGRFHEKDNLKRCVREALASNRMVAFLLLD--NSQESIMD 2240
HN QL ++I+DG + + +++ VR A + M+ F+++D S ESI+D
Sbjct: 4802 --------HNDQWQLEIVISDGICEDHETIQKLVRRARENKIMLVFVIIDGITSNESILD 4853
Query: 2241 LMEAS-----FEGGKMKFSKYMDSFPFPYYIVLRNIEALPRTLANLLRQ 2284
+ + + + ++K +KY+D+FPF +Y+V+ +I LP L+ +LRQ
Sbjct: 4854 MSQVNYIPDQYGNPQLKITKYLDTFPFEFYVVVHDISELPEMLSLILRQ 4902
Score = 87.4 bits (215), Expect = 5e-15
Identities = 109/506 (21%), Positives = 204/506 (39%), Gaps = 59/506 (11%)
Query: 446 FKFKPRAFQIESIMELEIPALANSSATEAFSDWKEFSYEEKSADNMESSEECEILDEEWK 505
FKF R + I E + L + + F +E E + ++ + ++ + + +++
Sbjct: 3123 FKFHKRDTNLLEIFEAALYTLYSRWSVRRFRQEQE---ENEKSNMFKFNDNSDDYEADFR 3179
Query: 506 HLEESILDNVVLIHSQLFGSGDLVQ------APGIFEISDEDRLHSFSESYKLG--INLI 557
L D ++ + + S + + A + D+D +FS K G I I
Sbjct: 3180 KLFPDYEDTALVTNEKDISSPENLDDIYFKLADTYISVFDKDHDANFSSELKSGAIITTI 3239
Query: 558 KGAHSSNLASLDAKLIPEHLFYLSIDYRRKFHSSSKSANRYNFYKDSNAHEIEQMLKVLA 617
N + K ++D + +++ +FY D + E ++ ++
Sbjct: 3240 LSEDLKNTRIEELKSGSLSAVINTLDAETQSFKNTEVFGNIDFYHDFSIPEFQKAGDIIE 3299
Query: 618 PLRQQITSLLNEWEEQNDLQRFLDVIDMLLTLPSDIPLAKAFSGL-QFLLHKAQVMQENH 676
+ + + LL +W E L+ V L P PLA+ + Q + A+ +
Sbjct: 3300 TVLKSVLKLLKQWPEHATLKELYRVSQEFLNYPIKTPLARQLQKIEQIYTYLAEWEKYAS 3359
Query: 677 SKFTFSNQLKSVFDLMSSWHKMELGSWPVLLDEVMDQYENNAKKSVLSSSIHYF*SINFP 736
S+ + +N +K + DL+ SW K+EL +W L + + +KS+ + + SI
Sbjct: 3360 SEVSLNNTVKLITDLIVSWRKLELRTWKGLFNSE----DAKTRKSIGKWWFYLYESIVI- 3414
Query: 737 KSNFYFSYESC---------SLEDFIQTSSFGEFRKRLQLLYAFLGQNHTSACLKINSSN 787
SNF + SL F S+ GEF RL L+ AF H + + SS
Sbjct: 3415 -SNFVSEKKETAPNATLLVSSLNLFFSKSTLGEFNARLDLVKAFY--KHIQL-IGLRSSK 3470
Query: 788 IVFFLHCWTLQLLSDGAVNILVQYVWILCAVLTNHIDASRKEILTELKDLVKLCRWEQDK 847
I LH + Q+ ++ +TN +K + E+ D++ L W+
Sbjct: 3471 IAGLLH---------NTIKFYYQFKPLIDERITN----GKKSLEKEIDDIILLASWKDVN 3517
Query: 848 SYSSIENLKKSRQKLKKLIKKHTDILQEPMDKLIRDVLHKGSISGVSDLPLFSDENRLYQ 907
+ ++ +KS L K+++K+ D+L +I L L+S+EN+L
Sbjct: 3518 VDALKQSSRKSHNNLYKIVRKYRDLLNGDAKTIIEAGL------------LYSNENKLKL 3565
Query: 908 EGWKDVWHMIENIYIKAVDSGNIWKE 933
K H E+ ++A S N+ KE
Sbjct: 3566 PTLKQ--HFYEDPNLEA--SKNLVKE 3587
Score = 68.2 bits (165), Expect = 3e-09
Identities = 100/489 (20%), Positives = 193/489 (39%), Gaps = 64/489 (13%)
Query: 1540 GDGSNKELRAKDDSTSDQSGDDSCDEGDAQNDEAAAQNEFDDEENGDDVNMDKEAA---H 1596
GDG + KD + +D+ +E Q D ++E DDE D V M+ + A
Sbjct: 4065 GDGEGAQNNNKDVEQDEDLTEDAQNENKEQQD----KDERDDENEDDAVEMEGDMAGELE 4120
Query: 1597 SDATGLKPDEPDHSSDMEIDLNANEDVDPIEEGDQEG-----HDDSAENGNQEDETCPPD 1651
+ G + D+ D S+ E +E++D + E D DD A + ++E +T D
Sbjct: 4121 DLSNGEENDDEDTDSEEE---ELDEEIDDLNEDDPNAIDDKMWDDKASDNSKEKDT---D 4174
Query: 1652 EIMEEAHTEVDV-SSEKDDLGQEHQENDDMNSMDPKNDTSESSDVVNPQVSN------VD 1704
+ ++ + E DV ++E D+ ++++E D + P++ E + N + N +
Sbjct: 4175 QNLDGKNQEEDVQAAENDEQQRDNKEGGDEDPNAPEDGDEEIENDENAEEENDVGEQEDE 4234
Query: 1705 LASQSKSDLQTSGSE----NIASQSNLSNSHHDFGNPA-VTGGFPSSDMSEMDINMSDSS 1759
+ + DL+ + E ++ NL + H + ++ G P D+N +
Sbjct: 4235 VKDEEGEDLEANVPEIETLDLPEDMNLDSEHEESDEDVDMSDGMPD------DLNKEEVG 4288
Query: 1760 NTGGFSKTQPKSHLPQHEHSFSQEKQTNPSRSTGDALDFRKEKINVSGDLPEDNIEHHGE 1819
N K + E+ + + D + +E ++++ D +++ E+ E
Sbjct: 4289 NEDEEVKQESGIESDNENDEPGPEEDAGETETALDEEEGAEEDVDMTNDEGKEDEENGPE 4348
Query: 1820 ---MDDNNADEYGYVSEFEKGTTQALGPATLEQVDRNIDVDKVDTESRAGEDANLQ---- 1872
M D + E K L+ V+ D + +D E+ +D+ +
Sbjct: 4349 EQAMSDEEELKQDAAMEENKEKGGEQNTEGLDGVEEKADTEDIDQEAAVQQDSGSKGAGA 4408
Query: 1873 LEKQNSEIDSVSNSSLLPKNEKRDQANMPV-MEKSQDD--GSVKPLGSANIDPESHLEDL 1929
E D V S + DQ ++ E+S+++ ++K LG + + +D+
Sbjct: 4409 DATDTQEQDDVGGSGTTQNTYEEDQEDVTKNNEESREEATAALKQLGDSMKEYHRRRQDI 4468
Query: 1930 ISISRSYLGENTHKLSQLSVNDEELGKYHEPCDAPDHVKDNATALWRRYELSTTKLSQEL 1989
+ GE DE L K +E D +HV+ T E T L
Sbjct: 4469 KEAQTN--GE----------EDENLEKNNERPDEFEHVEGANT------ETDTQALGSAT 4510
Query: 1990 TEQLRLVLE 1998
+QL+ + E
Sbjct: 4511 QDQLQTIDE 4519
Score = 60.5 bits (145), Expect = 6e-07
Identities = 81/387 (20%), Positives = 154/387 (38%), Gaps = 52/387 (13%)
Query: 1555 SDQSGDDSCDEGDAQNDEAAAQNEFDDEENGDDVNMDKEAAHSDATGLKPDEPDHSSDME 1614
S++ D + EG D AQN D E +D+ D + + + K + D + D
Sbjct: 4050 SEEVDDKNLQEGTGLGDGEGAQNNNKDVEQDEDLTEDAQNENKEQQD-KDERDDENEDDA 4108
Query: 1615 IDLNANEDVDPIEEGDQEGHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEH 1674
+++ EGD G + NG + D DE + E+D E DDL +
Sbjct: 4109 VEM----------EGDMAGELEDLSNGEEND-----DEDTDSEEEELD--EEIDDLNE-- 4149
Query: 1675 QENDDMNSMDPKNDTSESSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNSHHDF 1734
DD N++D K ++SD + ++ +L +++ + +EN Q + +
Sbjct: 4150 ---DDPNAIDDKMWDDKASDNSKEKDTDQNLDGKNQEE-DVQAAENDEQQRDNKEGGDED 4205
Query: 1735 GNPAVTG---------GFPSSDMSEMDINMSDSSNTGGFSKTQPKSH---LPQHEHSFSQ 1782
N G +D+ E + + D P+ LP+ + S+
Sbjct: 4206 PNAPEDGDEEIENDENAEEENDVGEQEDEVKDEEGE-DLEANVPEIETLDLPEDMNLDSE 4264
Query: 1783 EKQTNPSRSTGDAL--DFRKEKINVSGDLPEDNIEHHGEMDDNNADEYGYVSEFEKGTTQ 1840
++++ D + D KE++ G+ E+ + G DN DE G E + G T+
Sbjct: 4265 HEESDEDVDMSDGMPDDLNKEEV---GNEDEEVKQESGIESDNENDEPG--PEEDAGETE 4319
Query: 1841 ALGPATLEQVDRNIDVDKVDTESRAGEDANLQLEKQNSEIDSVSNSSLLPKNEKRDQANM 1900
A E+ DVD + E + E+ + + + E + ++++ EK + N
Sbjct: 4320 T---ALDEEEGAEEDVDMTNDEGKEDEENGPEEQAMSDEEELKQDAAMEENKEKGGEQNT 4376
Query: 1901 PVMEKSQDDGSVKPLGSANIDPESHLE 1927
+ DG + + +ID E+ ++
Sbjct: 4377 EGL-----DGVEEKADTEDIDQEAAVQ 4398
>UniRef100_UPI000034DD79 UPI000034DD79 UniRef100 entry
Length = 5257
Score = 290 bits (741), Expect = 5e-76
Identities = 261/903 (28%), Positives = 410/903 (44%), Gaps = 183/903 (20%)
Query: 1448 QKKEEQEESKEVPGNDNTGIEMDQDFQADAVSLSEDSSENEDCDGENEELESE----MGP 1503
++KEEQ+E K + DN IEM +DF + E+ ++ ++ E+EE E E MG
Sbjct: 4463 EQKEEQKEEK-IKSEDNA-IEMSEDFDGQTYDMDENEADKDNDTSEDEEEEQELDKKMGD 4520
Query: 1504 TGPD-SEAVGEKIWDQNEDETPDDTGEKYESGPSVKDG-DGSNKELRAKDDS--TSDQSG 1559
G ++ + EK+W +ED DD E+++ G D + EL AKDD T+D S
Sbjct: 4521 LGEGHTDTLDEKMWGDDEDN--DDKEEEFKKEEKSGRGMDQTKSELAAKDDDLETADPSK 4578
Query: 1560 DDSCDEGDAQNDEA----AAQNEFDDEENG------------------DDVNMDKEAAHS 1597
D DE D+Q +E Q +FD+ E +++N+D+E AH
Sbjct: 4579 DKG-DETDSQTEEKINEQGDQRDFDENEVDPYHGQQDTRPEPEAMDLPEELNLDQEEAHD 4637
Query: 1598 DAT-----------GLKP---DEPDHSSDMEIDLNANEDVD------PIEEGDQEGHDDS 1637
D G K DE D +D E + E+++ P EE QE D+
Sbjct: 4638 DGPDEDREENPFDIGEKTSAVDEEDKQNDGEGEEETAEEMEEIQTSHPEEESAQEPQDEE 4697
Query: 1638 AENGNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEHQENDDMNSMDPKNDTSESSDVVN 1697
+N + P +E EEA+ KD+ G+E D +D + E +DV
Sbjct: 4698 EKNVGDDKNNNPVEENEEEAN--------KDEKGKEAVNGDPRVPVDEEQRPKEGADVEE 4749
Query: 1698 --PQVSNVD----LASQSKSDLQTSGSENIASQ-SNLSNSHHDFGNPAVTGGFPSSDMSE 1750
P+ S + S+ ++Q+ + +A + S + + GN A S+ E
Sbjct: 4750 ELPESSEREEHGASGQTSEQNIQSDTAVELAGEVSEKDQAKEEHGNGAADAN--QSEGHE 4807
Query: 1751 MDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEKQTNPSRSTGDALDFRKEKINVSGDLP 1810
+ +S T KTQ P H + S GD + K+++
Sbjct: 4808 SKLTARLTSQTQVEKKTQNFKRKPGHADN---------QHSAGDYNEQIKKRLRT----- 4853
Query: 1811 EDNIEHHGEM-DDNNADEYGYVSEFEKGTTQALGPATLEQVDRNIDVDKVDTESRAGEDA 1869
+E E+ DN + SE + Q T K + + E+
Sbjct: 4854 ---VERKEELAPDNRQSDVKQESELYQHVMQE---ETAYDTQTYAGSQKDQDDGKTNEET 4907
Query: 1870 NLQLEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKSQDDGSVKPLGSANIDPESHLE-D 1928
+++E Q ++++V L P+ L S NI SH E D
Sbjct: 4908 AMEMENQEEDLEAVEAQELKPEQ----------------------LDSKNI---SHKEID 4942
Query: 1929 LISISRSYLGENTHKLSQLSVNDEELGKYHEPCDAPDHVKDNATALWRRYELSTTKLSQE 1988
L E K +L +L +HE A ++W +Y+ T+ LSQ+
Sbjct: 4943 L---------EQARKEMEL-----QLEAWHELSPGSKEEMSAAFSMWHQYQHLTSTLSQQ 4988
Query: 1989 LTEQLRLVLEPTVASKLQGYYKTGKRIHMKKVIQFIASYYRMDKIWLRRTRPNKRDYQVV 2048
L EQLRL+LEPT+A+KL+G Y+TGKR++M+KVI +IAS +R DKIWLRRT+P+KRDYQ+
Sbjct: 4989 LCEQLRLILEPTLAAKLKGDYRTGKRLNMRKVIPYIASQFRKDKIWLRRTKPSKRDYQIC 5048
Query: 2049 IAVDDSHSMSESCCGDVAVEALVTVCRAVSQLEMGSLAVASFGTKGNINLLHDFDSPFTA 2108
+A+DDS SM ++ +A E+L + A++ LE+G ++V SFG ++ LLH F F
Sbjct: 5049 LAIDDSSSMVDNHSKQLAFESLSVIVNALTLLEVGQVSVYSFGE--HVQLLHPFHQQFND 5106
Query: 2109 ESGVKVSRIYTSLVFFFIDISTVHLLNMLKGSDCSFLTEEQMVSNLTFKQENTIADEPVV 2168
ESG ++ R+ C F ++ ++ F + +T
Sbjct: 5107 ESGARILRL------------------------CQFQQKKTRIAQ--FLETST------- 5133
Query: 2169 DLLKFLTNKLDAAVVKARLPSGHNPLQQLVLIIADGR---FHEKDNLKRCVREALASNRM 2225
K+ A + S + QL+LI++DGR KD + VR AL +N
Sbjct: 5134 --------KMFLAAQQHTPGSVNRETAQLLLIVSDGRGMFVEGKDRVTAAVRAALTTNVF 5185
Query: 2226 VAFLLLD--NSQESIMDLMEASFE--GGKMKFSKYMDSFPFPYYIVLRNIEALPRTLANL 2281
+ F++LD NS++S++D+ F+ G + YMD FPFP+Y++LR+I ALP TL++
Sbjct: 5186 IIFVVLDSPNSRDSVLDIKVPIFKSPGEMPEIRSYMDEFPFPFYVILRDINALPETLSDA 5245
Query: 2282 LRQ 2284
LRQ
Sbjct: 5246 LRQ 5248
Score = 92.8 bits (229), Expect = 1e-16
Identities = 91/336 (27%), Positives = 134/336 (39%), Gaps = 59/336 (17%)
Query: 594 SANRYNFYKDSNAHEIEQMLKVLAPLRQQITSLLNEWEEQNDLQRFLDVIDMLLTLPSDI 653
S Y+FY N E VL L + L +W E M +L S
Sbjct: 3487 SEGPYDFYHQPNMKEARLCFSVLEQLNVAVNQRLQDWPEHPXRI-------MAFSLAS-- 3537
Query: 654 PLAKAFSGLQFLLHKAQVMQENHSK-FTFSNQLKSVFDLMSSWHKMELGSWPVLLDEVMD 712
PLAK +GL+ LL KAQ + N S+ + +L+ V + W K+EL W LD VM
Sbjct: 3538 PLAKFLNGLEILLSKAQDWENNASRSVSLGKELEQVTQFIVQWRKLELNCWSSSLDNVMR 3597
Query: 713 QYENNAKKSVLSSSIHYF*--------------SINFPKSNFYFSYESCSLEDFIQTSSF 758
Q+ AKKS H+F S + S S SL+ FI++S+
Sbjct: 3598 QH---AKKSTR----HWFSIYQLIGRYLEERTSSSKTEEEPLSLSSVSSSLQAFIESSTL 3650
Query: 759 GEFRKRLQLLYAFLGQNHTSACLKINSSNIVFFLHCWTLQLLSDGAVNILVQYVWILCAV 818
GEF RL LL +F HC L + + L +W L
Sbjct: 3651 GEFHTRLALLLSF---------------------HCHLLMVPNQPGQEPLSSLLWNLHKY 3689
Query: 819 LTNHIDAS-------RKEILTELKDLVKLCRWEQDKSYSSIENLKKSRQKLKKLIKKHTD 871
+ D R+ I ELKD VK+ RW +S ++++K+ + + K +KK +
Sbjct: 3690 YSQFSDCIQTTICQLRQPIEKELKDFVKISRWNDVSFWSIKQSVEKAHRTIFKFLKKFEE 3749
Query: 872 ILQEPMDKLIRDVLHKGSISGVSDLPLFSDENRLYQ 907
L P + + + + + L S EN + Q
Sbjct: 3750 ALSGPCLPALIEPESRSNNFDLDSLDQNSAENPIQQ 3785
Score = 60.8 bits (146), Expect = 5e-07
Identities = 52/220 (23%), Positives = 97/220 (43%), Gaps = 34/220 (15%)
Query: 110 ELYIQSTTTDFNFNYTIGCAWAHIGALRIHLLLSYNEVDPVMKYYCKYTQLEETISSLEL 169
E Y+++ + G W ++G L+I + DP +K K ++ +S L+
Sbjct: 2987 EQYVRNKVQSSDQLACSGVFWVNLGLLQIKVWTPQAIFDPAVKRSYKLIYAQQELSLLQE 3046
Query: 170 EIQVRKECGYLSGQFLTVEADKRKAE---------------RLEKLQAELRKLQRKIVFR 214
E + R LS Q +T A+ ++ R+++L+ ++ +L RK R
Sbjct: 3047 EWRSRS----LSSQMMT-GAELTESSITDGFQHPRIRYLWIRMQQLKEQIAELSRKQACR 3101
Query: 215 SESWKYKKLMNECDEFL---------KHIAS--LEVLVGNVEAED---LQQVIDRTHSWQ 260
Y +L E +L H+ S L L G+ A+ +Q ++ WQ
Sbjct: 3102 PNESHYGQLFQELQHYLCSIGQKSSVDHLLSRLLNALQGSSTAKSRSMVQGLLKEVAVWQ 3161
Query: 261 ETAMCFINRLTDEYTAYNDIIQPIQVAVYEMKFGLSLVLS 300
++ F +L D++ Y D++ PIQ + +++ G+SLV S
Sbjct: 3162 KSQQHFCQKLVDDFPLYPDVVGPIQTGILQLRHGMSLVAS 3201
>UniRef100_Q6CJB6 Similar to sp|Q12019 Saccharomyces cerevisiae YLR106c [Kluyveromyces
lactis]
Length = 4915
Score = 286 bits (732), Expect = 5e-75
Identities = 246/882 (27%), Positives = 422/882 (46%), Gaps = 115/882 (13%)
Query: 1448 QKKEEQEESKEVPGNDNTGIEMDQDFQADAVSLSEDSSENEDCDGEN--EELESEMGPTG 1505
Q+ + E+ +E ++ +EM+ D D + S+ +E ED + E+ +EL+ E+
Sbjct: 4096 QRNDSDEDDEE---KEDDAVEMEGDIAGDLENASDQENEEEDDNNEDDEDELDEEIDNLD 4152
Query: 1506 PDS-EAVGEKIWDQNEDETPDDTGEK-YESGPSVKDGDG-SNKELRAKDD-STSDQSGDD 1561
D A+ EK+W E+E DD+ EK E+ P + D E +A+DD D +
Sbjct: 4153 EDDPNALDEKMW---EEEAEDDSKEKDSENMPEKSNADDVQASEEQAEDDVKPEDHQQNQ 4209
Query: 1562 SCDEGDAQNDEAAAQNEFDDEENGDDVNMDKEAAHSDATGLKPDEPD-HSSDMEIDLNAN 1620
DE + + + E +EE D + E + + L+ + P+ + D+ D+N +
Sbjct: 4210 ETDEMETEEKDNDDDGEEQEEEEEDVGEQEDEVRNDENENLENNVPEVETMDLPEDMNLD 4269
Query: 1621 EDVDPIEEGDQEGHDDSAE--NGNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEHQEND 1678
D D E+G +E +D + ++E+E E E T +D S+ D+ +E E+
Sbjct: 4270 SDKDNEEDGSEEEEEDFEDKMEVDEEEEEGKQPENTENEQTNIDEESDADE-NRESDEDV 4328
Query: 1679 DMNSMDPKNDTSES----SDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNSHHDF 1734
DM+ D ++T E+ D P + +A S S+L+ E
Sbjct: 4329 DMDG-DDNSETEEALDKEDDTEKPDIKEEAIA-DSDSELENPQDEPKQEGGEDEKGEDVE 4386
Query: 1735 GNPAVTGGFPSSDMSEMDINMSDSSNTGG----FSKTQPKSHLPQHEHSFSQEKQTNPSR 1790
G + G D D + S G + ++ + + ++ SQ ++ N
Sbjct: 4387 GLDGLEGVEDDKDQINTDAAVEQDSGAKGEGSNAADSEEQQDIGSSGNAQSQSQENNQEE 4446
Query: 1791 STGDALDFRKEKINVSGDLPEDNIEHHGEM--------------DDNNADEYGYVSEFEK 1836
T + +E + GD ++ H E+ + DE+ +V
Sbjct: 4447 ITDTSRKDAQESLKQLGDSLKEFHRRHQEIKEASTNSEEQQPEGSNQKPDEFEHVDGANT 4506
Query: 1837 GT-TQALGPATLEQV---DRNIDVDKVDTESRA-GEDANLQLEKQNSEIDSVSNSSLLPK 1891
T TQALG A +Q+ D ++ +D+ E +A E+ N + +K +++ + P+
Sbjct: 4507 ETDTQALGSADKDQLTGFDEDLAIDEDSNEEKAEPENENDEDQKHPTDVMDIDE----PE 4562
Query: 1892 NEKRDQANMPVMEKSQDDGSVKPLGSANIDPESHLEDLISI-SRSYLGENTHKLSQ-LSV 1949
+ D ++ +++G K A I + LE+ ++ ++ + + + + Q L+
Sbjct: 4563 VQNGD------IDNEENNGKSK---GAFIGERNALENSGALWDQNDIVSDENDIDQILNE 4613
Query: 1950 NDEELGKYHEPCDAPDHVKDNATALWRRYELSTTKLSQELTEQLRLVLEPTVASKLQGYY 2009
D E+ + + AP D A LW+R E T +L+ L+EQLRL+LEPT+A+KL+G Y
Sbjct: 4614 VDNEVSEENSVAVAP-RPFDEARELWKRSEQETNELAAGLSEQLRLILEPTLATKLKGDY 4672
Query: 2010 KTGKRIHMKKVIQFIASYYRMDKIWLRRTRPNKRDYQVVIAVDDSHSMSESCCGDVAVEA 2069
KTGKR++MK++I +IAS YR DKIWLRRT+P+KR YQ++IAVDDS SMSES ++A ++
Sbjct: 4673 KTGKRLNMKRIIPYIASQYRKDKIWLRRTKPSKRQYQIMIAVDDSKSMSESKSVNLAFQS 4732
Query: 2070 LVTVCRAVSQLEMGSLAVASFGTKGNINLLHDFDSPFTAESGVKVSRIYTSLVFFFIDIS 2129
+ V +A++QLE G L++ FG + +H F+ PF ++G + F + D
Sbjct: 4733 ICLVSKALTQLESGGLSIVKFGE--TVREVHPFNQPFNTQTGAQ--------TFQWFD-- 4780
Query: 2130 TVHLLNMLKGSDCSFLTEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLDAAVVKARLPS 2189
F++ T + V + +K +AR
Sbjct: 4781 --------------------------FQETRTDVKKLVAESIKIFE--------RARAME 4806
Query: 2190 GHNPLQQLVLIIADGRFHEKDNLKRCVREALASNRMVAFLLLD--NSQESIMDLMEASF- 2246
N L QL +II+DG + + L R VR A + M+ F+++D NS ESIMD+ + ++
Sbjct: 4807 S-NDLWQLEIIISDGVCEDHETLVRLVRRARENKIMLVFVVIDGINSNESIMDMSQVNYI 4865
Query: 2247 --EGGKMKFS--KYMDSFPFPYYIVLRNIEALPRTLANLLRQ 2284
+ G MK S KY+D+FPF +Y+V+ +I LP L+ +LRQ
Sbjct: 4866 PDQFGNMKLSVQKYLDTFPFEFYVVVHDITELPEMLSIILRQ 4907
Score = 85.9 bits (211), Expect = 1e-14
Identities = 171/912 (18%), Positives = 344/912 (36%), Gaps = 188/912 (20%)
Query: 126 IGCAWAHIGALRIHLLLSYNEVDPVMKYYCKYTQLEETISSLELEIQVRKECGYLSGQFL 185
+G AW + L + + DP ++ Y Y S E I K +G L
Sbjct: 2896 LGKAWVLFAVGLLQLYVPSSPYDPAIRDYVIYDNYVAHKSLTESIIHNWK----CAGSVL 2951
Query: 186 TVEADKRKAERLEKLQAELRKLQRKIVFRSESWKYKKLMNECDEFLKHIASLEVLVGNVE 245
+ D + + ++ ++ + ++ VFR L +E F+ + ++ +E
Sbjct: 2952 FGDVDSYTQKLVPEVSSD-DEPKKPRVFRPNH-SIDSLFDEWSAFMLSTVDVTPVISLLE 3009
Query: 246 AEDLQQVID--RTHSWQETAMCFINRLTDEYTAYNDIIQPIQVAVYEMKFGLSLVLSSFL 303
+ I R +++ F++RL+ Y Y+DI VY MKFG +++
Sbjct: 3010 SSTEYNSISDSRFKMFEQNTSQFLSRLSSTYEVYSDINDIFAGYVYAMKFGFNVI----- 3064
Query: 304 EKEYLRKVGHENINLVTDMIYILMRFPRAASWKFISVEDVGVDLHSSYKLDFGTDFYLNM 363
+G EN S +LD F ++
Sbjct: 3065 ------SLGAEN---------------------------------ESQELDISPLFTVDC 3085
Query: 364 GLIERLITLSSGVSADKKVSAMRCRASIYWNILVQIAYSIANAKIIDRESYMLLHKIFDE 423
+ R ++ S S +++ ++ + + +I N ++S ++ + +
Sbjct: 3086 LAVTREKSILSHFS---RLNKFLKNQNVGSHDVEEILIHFLNLCYAHKDSESMIDSLNEI 3142
Query: 424 FASLWMSMKVYAKSKSDHDAQQ----FKFKPRAFQIESIMELEIPALANSSATEAFSDWK 479
L+ + + KS+ +A+Q FKF + IE+ + P +S + ++
Sbjct: 3143 LQPLYYRWSL-RRMKSEQEAEQKNSLFKFNDNSDDIEAEFKAMFPDYEDSVSLDS----- 3196
Query: 480 EFSYEEKSADNMESSEECEILDEEWKHLEESILDNVVLIHSQLFGSGDLVQAPGIFEISD 539
+E S ++D ++ + I+ ++F V +
Sbjct: 3197 ----------PVEESSATSLIDTYYE---------IAKIYIEIFEDASNVSLSQVMRKGS 3237
Query: 540 EDRLHSFSESYKLGINLIKGAHSSNLASLDAKLIPEHLFYLSIDYRRKFHSSSKSANR-- 597
E + L++ L +L+ ++ + LS K +S S+N
Sbjct: 3238 ET-----------SVILLRSCSDFKLYNLNESMVLAAIKTLS----EKTNSFKDSSNTEI 3282
Query: 598 YNFYKDSNAHEIEQMLKVLAPLRQQITSLLNEWEEQNDLQRFLDVIDMLLTLPSDIPLAK 657
++FY+ ++ E ++ V+ L + +LL EW E L+ V ++ P P+A+
Sbjct: 3283 FDFYRGTSRIETKKAQHVIQGLWNNVNTLLKEWPEHATLRDLFRVCKEFISYPVSTPMAR 3342
Query: 658 AFSGL-QFLLHKAQVMQENHSKFTFSNQLKSVFDLMSSWHKMELGSWPVLLDEVMDQYEN 716
+ Q + + SK + + S+ +L+ SW ++EL +W L +
Sbjct: 3343 LLQKIEQIYTFVVEWQKYASSKVSLQAHVDSITNLIVSWRRLELHTWKALFQ----MEDM 3398
Query: 717 NAKKSVLSSSIHYF*SI--NFPKSNFYFSYESCSLED----FIQTSSFGEFRKRLQLLYA 770
N+ K++ + + F +I +N S S SL F S+ GEF RL+L+ A
Sbjct: 3399 NSTKTIGNWWFYLFETIIVGTENANIDVSERSGSLLSALNVFFSKSTLGEFANRLRLVKA 3458
Query: 771 FLGQNHTSACLKINSSNIVFFLHCWTLQLLSDGAVNILVQYVWILCAVLTNHIDASRKEI 830
F H S +H T ++S NI+ Y +V+ + I +K +
Sbjct: 3459 FC--KHVSV------------MHGKT-SIISQALQNIISFYEQFT-SVVNDKIKTGKKLL 3502
Query: 831 LTELKDLVKLCRWEQDKSYSSIENLKKSRQKLKKLIKKHTDILQEPMDKLI--------- 881
E+ +++ L W+ + ++ ++S L K+++K+ +L EP+ +I
Sbjct: 3503 EKEISEVILLASWKDVNIDALKQSSRRSHNSLFKIVRKYRTLLSEPLTSMIESGIDSALP 3562
Query: 882 -------------RDVLHKGSISGVSDLPLFSDENRLYQEGWKDVWHMIEN--IYIKAVD 926
R + G+ S V+++P + ++ KD++ +N IYI +
Sbjct: 3563 VTKQFERVTISHFRSIDVSGAKSIVTNIPGWESRSK----SLKDIYITQKNLSIYISKIT 3618
Query: 927 SGN------------------------IWKEDKNN------QRKSRALSDLLNLLKTSGL 956
+ N ++K++K +KS+ LSD L LK GL
Sbjct: 3619 NQNYPDLLEYALYISKEAKRLREETPTVYKKEKKKLLATLKTQKSKLLSDSLKELKRIGL 3678
Query: 957 SQ--RKSTHKVK 966
R+ K++
Sbjct: 3679 KSNFREDIRKIQ 3690
Score = 66.2 bits (160), Expect = 1e-08
Identities = 93/458 (20%), Positives = 193/458 (41%), Gaps = 55/458 (12%)
Query: 1521 DETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQSGDDSCDEGDAQNDEAAAQNEFD 1580
+ET D+ + G + DGDG A+++S + +D ++ N + ++ D
Sbjct: 4053 EETEDNN---LQEGTGLGDGDG------AQNNSKDVEEDEDLLEDAQQPNKDQRNDSDED 4103
Query: 1581 DEENGDD-VNMDKEAAHS--DATGLKPDEPDHSSDMEIDLNANEDVDPIEEGDQEGHDDS 1637
DEE DD V M+ + A +A+ + +E D +++ + D +E++D ++E D D+
Sbjct: 4104 DEEKEDDAVEMEGDIAGDLENASDQENEEEDDNNEDDED-ELDEEIDNLDEDDPNALDEK 4162
Query: 1638 AENGNQEDETCPPD-EIMEEAHTEVDVSS-----EKDDLGQEHQENDDMNSMDPKNDTSE 1691
ED++ D E M E DV + E D ++HQ+N + + M+ + +
Sbjct: 4163 MWEEEAEDDSKEKDSENMPEKSNADDVQASEEQAEDDVKPEDHQQNQETDEME--TEEKD 4220
Query: 1692 SSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAVTGGFPSSDMSEM 1751
+ D Q + + + +++ +EN+ ++N+ P V + D+ E
Sbjct: 4221 NDDDGEEQEEEEEDVGEQEDEVRNDENENL--ENNV---------PEV----ETMDLPE- 4264
Query: 1752 DINM-SDSSNTGGFSKTQPKSHLPQHEHSFSQEKQTNPSRSTGDALDFRKEKINVSGDLP 1810
D+N+ SD N S+ + + + E +E+ P + + + +E
Sbjct: 4265 DMNLDSDKDNEEDGSEEEEEDFEDKMEVDEEEEEGKQPENTENEQTNIDEESDADENRES 4324
Query: 1811 EDNIEHHGEMDDNNADEYGYVSEFEKGTTQALGPATLEQVDRNIDVDKVDTESRAGEDAN 1870
+++++ G DDN+ E E + A + D ++ + + + GED
Sbjct: 4325 DEDVDMDG--DDNSETEEALDKEDDTEKPDIKEEAIADS-DSELENPQDEPKQEGGEDEK 4381
Query: 1871 LQ-------LEKQNSEIDSVSNSSLLPKNE--KRDQANMPVMEKSQDDGSVKPLGSANID 1921
+ LE + D ++ + + ++ K + +N E+ QD GS S N
Sbjct: 4382 GEDVEGLDGLEGVEDDKDQINTDAAVEQDSGAKGEGSNAADSEEQQDIGS-----SGNAQ 4436
Query: 1922 PESHLEDLISISRSYLGENTHKLSQLSVNDEELGKYHE 1959
+S + I+ + + L QL + +E + H+
Sbjct: 4437 SQSQENNQEEITDTSRKDAQESLKQLGDSLKEFHRRHQ 4474
>UniRef100_Q6CFC5 Similar to sp|Q12019 Saccharomyces cerevisiae Midasin [Yarrowia
lipolytica]
Length = 4696
Score = 282 bits (722), Expect = 8e-74
Identities = 257/914 (28%), Positives = 438/914 (47%), Gaps = 164/914 (17%)
Query: 1446 MMQKKEEQEESKEVPGNDNTGIEMDQDFQADAVSLSEDSSENEDCDGENEELESEMGP-T 1504
M Q+ E+QE+ + +D +E D +++ ++D E ED DGE EE E E+ T
Sbjct: 3863 MEQENEDQEDKDDDEDDDAVSVEGDMAGKSEN---AKDEEEGEDKDGEEEEEEEEIDDET 3919
Query: 1505 GP----DSEAVGEKIWDQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQSGD 1560
G D A+ +K+W N+DE D EK + G D DG +K+ ++ D G
Sbjct: 3920 GNLDDLDPNAMDDKMW--NDDEEVQD--EKEKDG----DVDGDDKDDGGEEGKQDD--GK 3969
Query: 1561 DSCDEGDAQNDEAAAQNEFDDEEN---GDDVNMDKEAAHSDATGLKPDEPDHSSDMEID- 1616
+EG+A+ E ++E + EEN GD+ +KE SD + E D + E D
Sbjct: 3970 QQGEEGEAETKEGEGEDEGEQEENEGDGDEGEQEKEEDDSDGESVDAQEDDVRNKQEGDE 4029
Query: 1617 ----LNANEDVDPIEEGDQEGHDDSAENGNQE-DETCPPDEIMEEAHTEVDVSSEKDDLG 1671
L+ +E ++ E+ + +G D+ E G E D+ D EE + DV E +DL
Sbjct: 4030 LDPHLDESEVLELPEDMNLDGMDEDKEEGEDEFDDGLDKDMSDEEGDGDEDVEMEDEDLN 4089
Query: 1672 ---QEHQENDDMNSMDPK----NDTSESSDVVNPQ-VSNV--DLASQSKSDL-----QTS 1716
+E +E D +D N+ E +D NP+ + NV D + K D+ +T
Sbjct: 4090 AGEEEPEEGADEEEVDEGAGEVNEDVEDADEKNPEEMDNVKEDAMEEEKMDVDQDDNETG 4149
Query: 1717 GSENIASQSNLSNSH--HDFGNPAVT------------GGFPSSDMSEMDINMSDSSNTG 1762
A + + H D G+ G +D E + ++ G
Sbjct: 4150 KQNEDAPELEMEGLHGQDDAGDQEENDESAVKQETGEKGSGQDADSKEEEEDVGGGGEAG 4209
Query: 1763 GFSKTQPKSH-------LPQHEHSFSQEKQTNPSRSTGDAL-DFRKEKINVSGDLPEDNI 1814
+ Q + + + +++ + + + GDAL +F K+K + +N
Sbjct: 4210 AKEEDQDEDQDEDQDDKTKEGQEDDAEDSRVDQMKQLGDALKEFHKKKEEIKNS---NND 4266
Query: 1815 EHHGEMDDNNAD--EYGYVSEFE-KGTTQALGPATLEQVDRNIDVDKVDTESRAGEDANL 1871
++D N D E+ +V + K TQA+G A DR++ D D + E +
Sbjct: 4267 SAQDDVDSANVDPQEFEHVDGPDSKHDTQAMGAA-----DRDVKQDIDDDMAMEDEQEEV 4321
Query: 1872 QLEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKSQDDGSVKPLGSAN---IDPESHLED 1928
+ E++N K E+ ++ E +D G+ P G+A+ ++ E+ +D
Sbjct: 4322 KPERRNEV-----------KQEEGEEPEEDAEEADEDGGA--PEGAASKTAVEGEAESDD 4368
Query: 1929 LISISRSYLGENTHKLSQLSVNDEELGKYHEPCDAPD-HVKDNATAL------WRRYELS 1981
+ S+ GE + ++ ++EEL + E D D + ++A +L W+ Y+ S
Sbjct: 4369 EEAESKVQ-GE----MMEVDSDEEELEEVEE--DIEDLSIDESAMSLSESRDKWKTYQSS 4421
Query: 1982 TTKLSQELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKVIQFIASYYRMDKIWLRRTRPN 2041
L+ L EQLRL+LEPT+A+K++G +KTGKR++MK++I +IAS ++ DKIW+RRT+P+
Sbjct: 4422 VADLATTLCEQLRLILEPTLATKMRGDFKTGKRLNMKRIIPYIASSFKKDKIWMRRTKPS 4481
Query: 2042 KRDYQVVIAVDDSHSMSES-CCGDVAVEALVTVCRAVSQLEMGSLAVASFGTKGNINLLH 2100
KR YQ++I+VDDS SM+ES C ++A +++ + +A++QLE G LAV FG + L+H
Sbjct: 4482 KRQYQIMISVDDSKSMNESPQCVELAFQSIALISKALTQLESGQLAVMKFGQ--DAQLVH 4539
Query: 2101 DFDSPFTAESGVKVSRIYTSLVFFFIDISTVHLLNMLKGSDCSFLTEEQMVSNLTFKQEN 2160
F+ F+ ESG ++VS +F Q+
Sbjct: 4540 PFEKTFSDESG------------------------------------GELVSKFSFAQDQ 4563
Query: 2161 TIADEPVVDLLKFLTNKLDAAVVKARLPSGHNPLQQLVLIIADGRFHEKDNLKRCVREAL 2220
T ++ K + N +D + + G L QL +II+DG + L++ VR A
Sbjct: 4564 T-------NVQKLVQNSID---IFQQQKLGGAELWQLQIIISDGICENHEVLRQLVRHAR 4613
Query: 2221 ASNRMVAFLLLD-----NSQESIMDLMEASF---EGGKM--KFSKYMDSFPFPYYIVLRN 2270
M+ F+++D + SI D+ +A + + G+M K KY+D+FPF +Y+++R+
Sbjct: 4614 ELKIMLVFVVIDALAAASGSSSITDIKQAKYISQDDGQMVLKMEKYLDTFPFEFYVIVRD 4673
Query: 2271 IEALPRTLANLLRQ 2284
I+ LP L+++LRQ
Sbjct: 4674 IKELPSVLSSVLRQ 4687
Score = 81.6 bits (200), Expect = 3e-13
Identities = 106/470 (22%), Positives = 201/470 (42%), Gaps = 53/470 (11%)
Query: 434 YAKSKSDHDAQQFKFKPRAFQIESIMELEIPALANSSATEAFSDW--KEFSYEEKSADNM 491
Y K KS D K + S AL T F+ W + EE++A +
Sbjct: 2903 YCKDKSVEDLSVEKTLSFVMDVVSKQGNSDTALVAYCCTTVFARWTLRRLRMEEQAA--I 2960
Query: 492 ESSEECEILDEEWKHLEESILDNVVLIHSQLFGSGDLVQAPGIFEISDEDRLHSFSESYK 551
ESS LDE EE +L +G++++ P + + D D H + +SY+
Sbjct: 2961 ESSGFSTNLDET---AEEEFAKLFPDYEIKLDDAGNVIK-PKVTK-QDVDYSH-WLKSYE 3014
Query: 552 L---GIN------LIKGAHSSN---LASLDAKLIPEHLFYLSIDYRRKFHSSSKSANRYN 599
G+ ++KGA + + + L+ H+ L D ++++ ++
Sbjct: 3015 RVFGGVEEPMSHVILKGAALATHGKVGHVMPSLLQAHVTVLETDCI----DVAEASPSFD 3070
Query: 600 FYKDSNAHEIEQMLKVLAPLRQQITSLLNEWEEQNDLQRFLDVIDMLLTLPSDIPLAKAF 659
FY+ +A E ++ + V L + + LL +W E + LQ+ + LL+ P+A+
Sbjct: 3071 FYRQHSAAETQKCVNVATKLLKFVNGLLAKWPEHDTLQQIAFQCNELLSFSVVTPVARLL 3130
Query: 660 SGLQFLLHKAQVMQENHSKFTFSNQLKSVFD-LMSSWHKMELGSWPVLLDEVMDQYENNA 718
+ ++ + ++ S+ + +F L+ SW ++EL WP L D +E A
Sbjct: 3131 AKVEQIYTFLHEWEKLASRDVSVREYIDIFTTLIVSWRRLELAMWPKLFD-----FEEEA 3185
Query: 719 KKSVLSSSIH--YF*SINFPKSNFYFSYESCS-----LEDFIQTSSFGEFRKRLQLLYAF 771
+K L Y + + N S + + L F+ S+ G++ RL+LL A
Sbjct: 3186 QKDGLGQWWFNVYEAVVVVCRDNSELSRDDITQLVQTLNLFLSQSTIGQYSFRLELLDAV 3245
Query: 772 LGQNHTSACLKINSSNIVFFLHCWTLQLLSDGAVNILVQYVWILCAVLTNHIDASRKEIL 831
L H + S N V A+ + Y + +T H+ A +K +
Sbjct: 3246 L--KHIGSMEPSTSVNQVTV------------ALKAFLVYYKMFVPSITAHVAARKKSLQ 3291
Query: 832 TELKDLVKLCRWEQDKSYSSIENLKKSRQKLKKLIKKHTDILQEPMDKLI 881
++++++ L W+ ++ E+ +KS +KL K++KK+ +L EP+ ++
Sbjct: 3292 KDIQEVILLASWKDTNVHALKESARKSHRKLFKVVKKYRTLLCEPVKSVL 3341
>UniRef100_O94248 SPCC737.08 protein [Schizosaccharomyces pombe]
Length = 4717
Score = 281 bits (718), Expect = 2e-73
Identities = 244/872 (27%), Positives = 411/872 (46%), Gaps = 130/872 (14%)
Query: 1452 EQEESKEVPGNDNTGIEMDQD------FQADAVSLSEDS----SENEDCDGENEELESEM 1501
E ++ +E+ ++T + D D ++D +++DS +EN D + EN++L+ E+
Sbjct: 3929 EDDDLEELANEEDTANQSDLDESEARELESDMNGVTKDSVVSENENSDSEEENQDLDEEV 3988
Query: 1502 GPTGPD-SEAVGEKIWDQ-NEDETPDDTGEKYESGPSVKDGD-----GSNKELRAKDDST 1554
D S ++ EK+WD+ NE++ + + E + + D NK L KD
Sbjct: 3989 NDIPEDLSNSLNEKLWDEPNEEDLLETEQKSNEQSAANNESDLVSKEDDNKALEDKDRQE 4048
Query: 1555 SDQSGDDSCDEG--DAQNDEAAAQNEFDDEENGDDVNMDKEAAHSDATG-LKPDEPDHSS 1611
+ + S D G D + N EN D +++ ++ + G + D
Sbjct: 4049 KEDEEEMSDDVGIDDEIQPDIQENNSQPPPENEDHLDLPEDLKLDEKEGDVSKDSDLEDM 4108
Query: 1612 DMEIDLNANEDVDPIEEGDQEGHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSEKDDLG 1671
DME E+ D ++ + +D E N DE D+ + A E D +D
Sbjct: 4109 DMEAADENKEEADAEKDEPMQDFEDPLEENNTLDEDIQQDDFSDLA--EDDEKMNEDGFE 4166
Query: 1672 QEHQENDDMNSMDPKNDTS-ESSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNS 1730
+ QEN++ K+D E +V Q + +KS ++ ++ + +
Sbjct: 4167 ENVQENEESTEDGVKSDEELEQGEVPEDQAIDNHPKMDAKSTFASAEADEENTDKGIVGE 4226
Query: 1731 HHDFGNP--AVTGGFPSSDMSEMDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEKQTNP 1788
+ + G A G + ++ + + ++ G + T PK + + + +
Sbjct: 4227 NEELGEEDGAAESGVRGNGTADGEFSSAEQVQKGEDTST-PKEAMSEADRQY-------- 4277
Query: 1789 SRSTGDALDFRKE--KINVSGDLPEDNIEHHGEMDDNNADEYGYVSEFEKGTTQALGPAT 1846
+S GD L ++ +I+ DL E + DD+ E+ +V E E+ QALG A
Sbjct: 4278 -QSLGDHLREWQQANRIHEWEDLTESQSQ---AFDDS---EFMHVKEDEEEDLQALGNAE 4330
Query: 1847 LEQVDRNIDVDKVDTESRAGEDANLQLEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKS 1906
+Q+ ++ID D E N DS++++++ ++ D+ ++
Sbjct: 4331 KDQI-KSIDRD----------------ESANQNPDSMNSTNIA--EDEADEVGDKQLQDG 4371
Query: 1907 QDDGSVKPLGSANIDPESHLEDLISISRSYLGENTHKLSQLSVNDEELGKYHE-----PC 1961
QD +K G + E SI++S E +LS+ ++EL Y+ P
Sbjct: 4372 QDISDIKQTGEDTLPTEFG-----SINQS---EKVFELSEDEDIEDELPDYNVKITNLPA 4423
Query: 1962 DAPDHVKDNATALWRRYELSTTKLSQELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKVI 2021
P D A LW ++E ST +LS EL EQLRL+LEPT+A+K+QG ++TGKR++MK++I
Sbjct: 4424 AMPI---DEARDLWNKHEDSTKQLSIELCEQLRLILEPTLATKMQGDFRTGKRLNMKRII 4480
Query: 2022 QFIASYYRMDKIWLRRTRPNKRDYQVVIAVDDSHSMSESCCGDVAVEALVTVCRAVSQLE 2081
+IAS ++ DKIW+RR +P+KR YQV+I++DDS SMSES +A+E L V +A+S LE
Sbjct: 4481 PYIASQFKKDKIWMRRVKPSKRTYQVMISIDDSKSMSESGSTVLALETLALVTKALSLLE 4540
Query: 2082 MGSLAVASFGTKGNINLLHDFDSPFTAESGVKVSRIYTSLVFFFIDISTVHLLNMLKGSD 2141
+G +AV FG + LLH FD F++ESGV
Sbjct: 4541 VGQIAVMKFGEQP--ELLHPFDKQFSSESGV----------------------------- 4569
Query: 2142 CSFLTEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLDAAVVKARLPSGHNPLQQLVLII 2201
QM S+ TF+Q NT V L + K A ++ ++QL +II
Sbjct: 4570 -------QMFSHFTFEQSNT-----NVLALADASMKCFNYANTASHHRSNSDIRQLEIII 4617
Query: 2202 ADGRFHEKDNLKRCVREALASNRMVAFLLLDN----SQESIMDLMEASF---EGGKM--K 2252
+DG + D++++ +R A M+ F++LDN + SI+D+ + + E G M K
Sbjct: 4618 SDGICEDHDSIRKLLRRAQEEKVMIVFVILDNVNTQKKSSILDIKKVYYDTKEDGTMDLK 4677
Query: 2253 FSKYMDSFPFPYYIVLRNIEALPRTLANLLRQ 2284
Y+D F F YY+V+RNIE LP+ L++ LRQ
Sbjct: 4678 IQPYIDEFAFDYYLVVRNIEELPQLLSSALRQ 4709
Score = 78.6 bits (192), Expect = 2e-12
Identities = 69/293 (23%), Positives = 136/293 (45%), Gaps = 31/293 (10%)
Query: 598 YNFYKDSNAHEIEQMLKVLAPLRQQITSLLNEWEEQNDLQRFLDVIDMLLTLPSDIPLAK 657
YNFY D N + ++ ++ + + SL+ W E L+ D ID +L L P+A+
Sbjct: 3125 YNFYSDPNPSKAIEVRDLIKIVESRAISLIKNWPENFVLRGLKDAIDAILNLSPFSPIAE 3184
Query: 658 AFSGLQFLLHKAQVMQENHSK-FTFSNQLKSVFDLMSSWHKMELGSWPVLLDEVMDQYEN 716
S L+ + H ++ S+ ++ +N++ + + W K EL +W LL +++Y+
Sbjct: 3185 YLSKLERVFHLLSEWEKLASREYSLANEMDLIKKKIIDWRKFELSNWNNLLK--LEEYKL 3242
Query: 717 NAK-----KSVLSSSI--HYF*SINFPKSNFYFSYESCS-LEDFIQTSSFGEFRKRLQLL 768
+ + S+L I +F + F K N ES S + FI + GEF+ L+ L
Sbjct: 3243 SERVYPRLYSILQFIILKPFFENSKFTKQNL---CESASIIVQFITDLTVGEFQLCLKCL 3299
Query: 769 YAFLGQNHTSACLKINSSNIVFFLHCWTLQLLSDGAVNILVQYVWILCAVLTNHIDASRK 828
+F + +A L+I H LL+ + Y + ++ I ++
Sbjct: 3300 LSF---SQHAASLRI--------CHGIDAMLLN------IYHYFEQFLSKVSEAIHTQKQ 3342
Query: 829 EILTELKDLVKLCRWEQDKSYSSIENLKKSRQKLKKLIKKHTDILQEPMDKLI 881
+ +K+ + L W+ Y+ E+ KKS +L K++ ++ ++L++P+ +
Sbjct: 3343 SLENSIKERILLMSWKDTNVYALKESAKKSHAELFKVLHRYREVLRQPVSSYL 3395
>UniRef100_UPI000023F705 UPI000023F705 UniRef100 entry
Length = 4911
Score = 280 bits (717), Expect = 3e-73
Identities = 234/907 (25%), Positives = 412/907 (44%), Gaps = 152/907 (16%)
Query: 1444 LSMMQKKEEQEESKEVPGNDNTGIEMDQDFQADAVSLS-----EDSSENEDCDGENEELE 1498
LS + ++ +EE+ E+ + D++ + D S+ E+ S+N D + E +++
Sbjct: 4082 LSELAQEANKEENGEMEDEKDAVDMADEELEGDMGSVDGAEDDEEGSKNGDEEEEENDMD 4141
Query: 1499 SEMGPTGP-DSEAVGEKIWDQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQ 1557
E G D AV EK+WD +++E EK + G K G + E A D+ Q
Sbjct: 4142 EEAGDVDDLDPTAVDEKMWDGDDEEK----AEKDQQGEKAK-GQKKDDEQLAGDEDAQKQ 4196
Query: 1558 SGDDSCD-----EGDAQNDEAAAQNEFDDEENGDDVNMDKEAAHSDATGLKP-------- 1604
G++ D E DA+ +E A E +D + +++N ++ A + T P
Sbjct: 4197 DGEEQPDVDDSGEQDAEEEEDEAGVEEEDVKTQEEMNKQEQTAQENDTLALPEDMDLDLG 4256
Query: 1605 ---------DEPDHSSDMEIDLNANEDVDPIEEGDQEGHDDSAEN----------GNQED 1645
D+ D SD+E + ED + ++GD++ D +AE G +ED
Sbjct: 4257 DEQEPASDSDDLDDLSDIEEEKKDVEDQEMGDDGDEDSDDAAAETQLQEEAGEEAGIEED 4316
Query: 1646 ETCPPDEIMEEAHTEVDVSSEKDDLGQEHQENDDMNSMDPKNDTSESSDVVNPQVSNVDL 1705
E P ++ + + +V E+++ +E ++ D N N T+++ +
Sbjct: 4317 EETPEEKAGGKDEVDEEVEPEEEEKAEEQEDATDQNQPPQDNATTDTDNA---------- 4366
Query: 1706 ASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAVTGGFPSSDMSEMDINMSDSS-NTGGF 1764
+ SD++TSG + A ++ ++ G +M E + S+ N G
Sbjct: 4367 ---APSDVKTSGQDQNADSMDVDDNFQSNAAQQEDG-----EMGEGAADQDTSAGNKGST 4418
Query: 1765 SKTQPKSHLPQHEHSFSQEKQTNPSRSTGDALD-FRKEKINVSGDLPEDNIEHHGEMD-- 1821
S+++ + E +++P + GDAL+ + +++ ++ D E + D
Sbjct: 4419 SQSKEITDRADQEQDKPDSARSDPFKKLGDALERWHRQQKDIKDAESSDANEQNAPQDPS 4478
Query: 1822 -DNNADEYGYVSEFEKGT-TQALGPATLEQVD-----RNIDVDKVDTESRAGEDANLQLE 1874
D E+ ++ + E T TQA+G A EQV ID +K D SR ++ + E
Sbjct: 4479 ADQGRKEFQHLQDDETATDTQAMGTADDEQVQPIDESMAIDEEKQDPTSRLMDEDKEETE 4538
Query: 1875 KQNSEIDSVSNSSLLPKNEKRDQANMPVMEKSQDDGSVKPLGSANIDPE--------SHL 1926
+ ++D+ + E D +N + D S N D E L
Sbjct: 4539 QDPDQMDTADTA------EAPDASNQDADKDQDDTRSGVKTRQGNYDRELSPSEQEAQML 4592
Query: 1927 EDLISISRSYLGENTHKLSQLSVNDEELGKYHEPCDAPDHVKDNATALWRRYELSTTKLS 1986
E+ + + E + +LS ++DEE P + W ++ T LS
Sbjct: 4593 EE--DQDEADIQETSTQLSITHISDEE---------RPLRDFGESMQQWTEFQTKTHSLS 4641
Query: 1987 QELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKVIQFIASYYRMDKIWLRRTRPNKRDYQ 2046
LT QLRL+L P+ ++KL G ++TGKR+ +K++I +IAS Y+ DKIW+RR+ P KR YQ
Sbjct: 4642 LSLTSQLRLILTPSQSTKLSGGFRTGKRLSIKRIIPYIASSYKRDKIWMRRSIPTKRTYQ 4701
Query: 2047 VVIAVDDSHSMSESCCGDVAVEALVTVCRAVSQLEMGSLAVASFGTKGNINLLHDFDSPF 2106
+++ VDDS SM E+ G +A+E+LV V R+++ LE G + V FG ++ H PF
Sbjct: 4702 ILLCVDDSKSMGETSSGTLAMESLVMVSRSLTMLEAGQVGVMGFG--ADVFAAHCLTEPF 4759
Query: 2107 TAESGVKVSRIYTSLVFFFIDISTVHLLNMLKGSDCSFLTEEQMVSNLTFKQENTIADEP 2166
+++G KV + F Q+ T
Sbjct: 4760 ASDAGAKV------------------------------------LQKFNFSQDRT----- 4778
Query: 2167 VVDLLKFLTNKLDAAVVKARLPSGHNPLQQLVLIIADGRFHEK--DNLKRCVREALASNR 2224
D+ + ++ + SG+ L QL LI++DG + ++R +REA+
Sbjct: 4779 --DIGLLIQRTIETFREARQQSSGNTDLWQLALILSDGLTPSSAHEGIRRMLREAMEERI 4836
Query: 2225 MVAFLLLDNS----QESIMDLMEASF--EGGKMK--FSKYMDSFPFPYYIVLRNIEALPR 2276
M+ F+++D++ +S+++L EA F +GG+ K +Y+D+FPF YY+++ N+E LP
Sbjct: 4837 MIVFIIMDDTGKKKGDSVLELKEAKFVRDGGESKVVIERYLDTFPFQYYLIVHNLEELPS 4896
Query: 2277 TLANLLR 2283
LA LLR
Sbjct: 4897 ALAGLLR 4903
Score = 68.2 bits (165), Expect = 3e-09
Identities = 97/430 (22%), Positives = 176/430 (40%), Gaps = 51/430 (11%)
Query: 561 HSSNLASLDAKLIPEHLFYLSIDYRRKFHSSSKSANRYNFYKDSNAHEIEQMLKVLAPLR 620
H + +L +K++ +F+L+ D S + YNFY D+N E Q++ ++ ++
Sbjct: 3221 HKNIDRNLTSKMLAGTMFFLN-DKLESLISPTVDKG-YNFYTDANVPEARQLVALMYKIK 3278
Query: 621 QQITSLLNEWEEQNDLQRFLDVI---DMLLTLPSDIPLAKAFSGLQFLLHKAQVMQ---- 673
+ L +E +Q DVI D +L L PLAK +++L Q
Sbjct: 3279 ARFREL-QMVDEIGHMQPLADVIQACDQVLELVHSEPLAKILPKVEYLHGHVYEWQFGGW 3337
Query: 674 --ENHSKFTFSNQLKSVFDLMSSWHKMELGSWPVLLDEVMDQYENNAK-------KSVLS 724
+ + T N L D + W ++EL +W L D + +++A + V++
Sbjct: 3338 ASKIYGVLTLHNLLT---DTVIRWRRLELSTWANLFDMEQKKCQDDAYSWWFVAYQVVIA 3394
Query: 725 SSIHYF*SINFPKS-NFYFSYESCSLEDFIQTSSFGEFRKRLQLLYAFLGQNHTSACLKI 783
+ ++ PK Y + SLE + T+ G++ RL LL Q+H LK+
Sbjct: 3395 VPLSL---VDVPKEMEEYAASLISSLEMYFSTAIVGQYGARLALLRQL--QSH----LKL 3445
Query: 784 NSSNIVFFLHCWTLQLLSDGAVNILVQYVWILCAVLTNHIDASRKEILTELKDLVKLCRW 843
+ + LQ++ N +QY ++ + R I ++KD++ + W
Sbjct: 3446 LTEDYP------VLQVILHSLSNF-IQYYSRYEKIMEETLQKGRLPIEKKMKDVLLMASW 3498
Query: 844 EQDKSYSSIENLKKSRQKLKKLIKKHTDILQEPMDKLI------RDVLHKGSISGVSDLP 897
+ + E+ +KS QKL ++I+K +L + ++I DV I S P
Sbjct: 3499 KDTNINALRESARKSHQKLFRIIRKFRGVLGQQAKQIIEQGLPDEDVRRMAHIDNKSPAP 3558
Query: 898 -----LFSDENRLYQEGWKDVWHMIENIYIKAVDSGNIWKEDKNNQRKSRALSDLLNLLK 952
+FS N GW D + N+ I + + + D ++ L
Sbjct: 3559 EVPADVFSKLNET-MPGWIDGHKRLANVSKTVSVMRKISDNPDMSSDVPQTIDDYVSSLS 3617
Query: 953 TSGLSQRKST 962
S + RK T
Sbjct: 3618 ESMVELRKET 3627
>UniRef100_Q7RYV1 Hypothetical protein [Neurospora crassa]
Length = 4992
Score = 280 bits (715), Expect = 5e-73
Identities = 247/916 (26%), Positives = 417/916 (44%), Gaps = 150/916 (16%)
Query: 1444 LSMMQKKEEQEESKEVPGNDNTGIEMDQDFQADAVSLSEDSSENE-DCDGENEELESEM- 1501
L+ Q + Q + ++ P + G E D + +V E+ EN+ D DG ++E + EM
Sbjct: 4142 LAQDQNNKNQNDIEDNPDAVDMG-EDDLEGDMGSVKAEEEDEENQKDKDGSDDEEDDEMD 4200
Query: 1502 ----GPTGPDSEAVGEKIWDQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQ 1557
G D AV EK+WD +DE + +K E+ +D D K+ Q
Sbjct: 4201 EEAGGVDDLDPTAVDEKMWD-GKDEEDAEKDQKGENNSGKQDEDEQAAAEPGKEKKEQQQ 4259
Query: 1558 SGDDSCDEGDAQNDEAAAQNEFDDEENGD-------DVNMDKEAAHSDATGLKPDEPDHS 1610
+++ E + + ++ + E +DEE G+ D +E + D + D
Sbjct: 4260 ESEEAVGEEEEKKEKKEGEEENEDEEEGEPGQEQEGDAQPQEELNNQDQNVQEQDTLALP 4319
Query: 1611 SDMEIDLNANED-----VDPIEEGDQEGHDDSAENGNQEDETCPPDEIMEEAHTEVDVSS 1665
DM+ID++ ED +D +E+G++ ++G E+E P + + EE E +
Sbjct: 4320 DDMQIDISDGEDEEEDNLDDLEDGEKP------QDGEMEEEQAP-NGVEEEQQLEEQKDA 4372
Query: 1666 EKDDLGQEHQENDDMNSMDPKN-----DTSESSDVVNPQVSNVDLASQSK-----SDLQT 1715
EK + E +E DD+N MD N D E D PQ + + + K +D Q
Sbjct: 4373 EKPEEA-EAEETDDLNPMDEDNMDVDMDKEEEQDEDAPQDLDKEEEDKEKEQPGLNDDQA 4431
Query: 1716 SGSENIASQSNLS-------NSHHDFGNPAVTGGFPSSDMSEMDINMSDSSNTGGFSKTQ 1768
++ A+ S++ + +D + + ++ SD N G Q
Sbjct: 4432 QADDDNAAPSDVKTGGGLAQDDQNDMQDDTADNKAAQREQGAVNNQSSDQDNAPGSKGEQ 4491
Query: 1769 PKSHLPQHEHSFSQ-EKQTNPSRSTGDALDFRKEKINVSGDLPEDNIEHHGEMDDNNADE 1827
++ + + + E + P + GDALD + PE E D E
Sbjct: 4492 SRTEQQEGPNEDQETEASSQPFKKLGDALDRWYRNQRDIRNAPESKEEQQKPDVDMAKVE 4551
Query: 1828 YGYVSEFE-KGTTQALGPATLEQVDRNIDVDKVDTESRAGEDANLQL---------EKQN 1877
+ ++ + + + TQALG A E+V D +DTE EDAN + + +
Sbjct: 4552 FQHLQDEDAEPDTQALGTANDEEVRPMDDAMAIDTEM---EDANNHVLPEDEPAAEDNKQ 4608
Query: 1878 SEID----SVSNSSLLPKNEKRD-----QANMPVMEKSQDDGSVKPLGSANIDPESHLED 1928
++D +S+ PK +++D + E S D+ S SA E L++
Sbjct: 4609 EDVDMEDAEAPDSTDAPKEDRKDGRSGVATHQGAFEDSDDEDSDARKASAK---EGDLDE 4665
Query: 1929 LISISRSYLGENTHKLSQLSVNDEELGKYHEPCDAPDHVKD--NATALWRRYELSTTKLS 1986
I+ E++ +LS + + D+ P ++D A ++W ++ T LS
Sbjct: 4666 AIN------EESSTQLSAIHLEDQP----------PRPLRDFNEALSMWTTFQTKTQSLS 4709
Query: 1987 QELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKVIQFIASYYRMDKIWLRRTRPNKRDYQ 2046
L+ QLRL+L P+ ++KL G ++TGKR+++KK+I +IAS Y+ DKIW+RR P KR YQ
Sbjct: 4710 MSLSSQLRLILTPSQSTKLSGSFRTGKRLNIKKIIPYIASSYKRDKIWMRRAIPTKRSYQ 4769
Query: 2047 VVIAVDDSHSMSES-----CCGDVAVEALVTVCRAVSQLEMGSLAVASFGTKGNINLLHD 2101
+++ VDDS SM +S G +A+E+LV RA++ LE+G + V FGT ++ + H
Sbjct: 4770 ILLCVDDSQSMGDSLNNSGSAGRLALESLVMTSRALTMLEVGQVGVLGFGT--DVFVAHR 4827
Query: 2102 FDSPFTA-ESGVKVSRIYTSLVFFFIDISTVHLLNMLKGSDCSFLTEEQMVSNLTFKQEN 2160
PF + ++G +V + TFKQE
Sbjct: 4828 LTDPFASHDAGARV------------------------------------LQQFTFKQEG 4851
Query: 2161 TIADEPVVDLLKFLTNKLDAAVVKARLPSGHNPLQQLVLIIADGRFHEKDN--LKRCVRE 2218
T +V+LL+ + A + + SG L QL LI++DG KD+ L+ +RE
Sbjct: 4852 T----DMVNLLRRTIDHFRDARLTSASQSGGEDLWQLALILSDGLVQSKDHARLRPLLRE 4907
Query: 2219 ALASNRMVAFLLLDNSQ----------ESIMDLMEASF-EGGKMKFSKYMDSFPFPYYIV 2267
A+ MV F+++D+++ +S++DL EA F G +Y+DSFPF YY++
Sbjct: 4908 AMEQRVMVVFIVMDDARDAQGNAKKGSQSVLDLKEARFGSDGMPVIHRYLDSFPFQYYLI 4967
Query: 2268 LRNIEALPRTLANLLR 2283
+ +++ LP LA LLR
Sbjct: 4968 VHHLDDLPGALAGLLR 4983
Score = 83.2 bits (204), Expect = 9e-14
Identities = 89/360 (24%), Positives = 160/360 (43%), Gaps = 45/360 (12%)
Query: 568 LDAKLIPEHLFYLSIDYRRKFHSSSKSANRYNFYKDSNAHEIEQMLKVLAPLRQQITSLL 627
+DA L+P + L+ + + K S++ +N YNFY DS E+ + L ++ L+++ L
Sbjct: 3284 MDALLLPATI--LAFEDQIKAFSANVDSNNYNFYTDSILVEVRKALTLVTALKKRFQEL- 3340
Query: 628 NEWEEQNDLQRFLDVI---DMLLTLPSDIPLAKAFSGLQFLL------HKAQVMQENHSK 678
EE Q DVI D +L + D PLA S ++ L H+ + H
Sbjct: 3341 QTIEEIGHHQTLADVIIACDKVLDMSIDDPLAAIISPMEKLYAHVYEWHEGGWATKAHKA 3400
Query: 679 FTFSNQLKSVFDLMSSWHKMELGSWPVLLDEVMDQYENNAKK-------SVLSSSIHYF* 731
+L+ D + W ++EL SW LLD + ++AK +V+ +
Sbjct: 3401 TVLYEKLR---DTICDWRRLELSSWSRLLDAEAKKCHDDAKSWWFIAYGAVILQPCSW-- 3455
Query: 732 SINFPKSNFYFSYESC-SLEDFIQTSSFGEFRKRLQLLYAFLGQNHTSACLKINSSNIVF 790
+ K + ++ E +LE + T+S G+F RL LL Q L ++
Sbjct: 3456 -LQEGKDLYAYAVELLGALESYFNTASLGQFTSRLNLLRQLRNQLEL---LMVDEPQ--- 3508
Query: 791 FLHCWTLQLLSDGAVNILVQYVWILCAVLTNHIDASRKEILTELKDLVKLCRWEQDKSYS 850
L ++ D N + + V I A R + ++KD++ L +W +DK+
Sbjct: 3509 ------LSVIRDAVQNFITYHARYERKV-KEAIAAGRTPLDRKMKDVLLLSKW-RDKNIE 3560
Query: 851 SIE-NLKKSRQKLKKLIKKHTDILQEPMDKLIRDVL----HKGSISGVSDLPLFSDENRL 905
++ + +KS QKL KL++K +L +P+ + L HK ++ V + +D+ +
Sbjct: 3561 ALRASARKSHQKLFKLVRKFRGVLSQPVSGITEQGLPEEEHKSLVAIVDKAAVQADQEAI 3620
>UniRef100_Q74ZY4 AGR074Cp [Ashbya gossypii]
Length = 4899
Score = 279 bits (713), Expect = 8e-73
Identities = 217/863 (25%), Positives = 421/863 (48%), Gaps = 96/863 (11%)
Query: 1449 KKEEQEESKEVPGNDNTGIEMDQDFQADAVSL-SEDSSENEDCDGENEELESEMGPTGPD 1507
+K++ E S++ D+ ++M+ D + + +DS + ++ + E ++L+ E+ D
Sbjct: 4098 QKDQDERSED---EDDNAVDMEGDIAGELENAPGQDSGDEDEMEEEEKDLDEEIDDLDDD 4154
Query: 1508 SEAVGEKIWDQN-EDETPDDTGEKYESGPSVKDGDGSNKE-LRAKDDSTSDQSGDDSCDE 1565
A+ +K+W++ E++T + EK + D S +E A D++ +D + +D +E
Sbjct: 4155 PNAIDDKMWNEEPEEDTKEKESEKMPENSAADDVQASKEEDENANDNNQADGTAEDGREE 4214
Query: 1566 GDAQNDEAAAQNEFDDE-ENGDDVNMDKEAAHSDATGLKPD---------EPDHSSDMEI 1615
DA+ D E DDE ++ D+ +++ + L D + D +D +
Sbjct: 4215 DDAEEDGEEDVGEQDDEVKHEDNEDLEANVPEVETMDLPEDMNLDSGDEKDSDDGADDQF 4274
Query: 1616 DLNANEDVDPIEEGDQEGHDDSAENGNQ--EDETCPPDEIMEEAHTEVDVSSEKDDLGQ- 1672
D + + D +P E + E DD+ + N +DE P+E ++ D + D+
Sbjct: 4275 DDDMSVDEEPNAE-EMETKDDAIDENNMGSDDEALSPEEEQQDDGIAEDGEAASDEEADG 4333
Query: 1673 EHQENDDMNSMDPKNDTSESSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSNSHH 1732
+E D NS D + + +D + ++ + AS + L+ G E++A ++
Sbjct: 4334 AEEEGQDQNSEDELAE--DHADENKQEPADQEAASDKQQGLE--GIEDLADVQDIDMEAA 4389
Query: 1733 DFGNPAVTG-GFPSSDMSEMDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEKQTNPSRS 1791
+ +G G ++D E D N+ S + Q Q S+E+ +
Sbjct: 4390 VEQHAGASGEGAEAADSKEQD-NVGSSGMAQSHEQQQDNGEEVQDS---SREEAIESLKQ 4445
Query: 1792 TGDALDFRKEKINVSGDLPEDNIEHHGEMDDNNADEYGYVS-EFEKGTTQALGPATLEQV 1850
GD+L + + + E + + + DE+ +++ TQAL AT +Q+
Sbjct: 4446 LGDSLKEFHRRHQQIKEASNNEEETNADAANTRPDEFEHINGAATDADTQALDTATKDQL 4505
Query: 1851 DRNIDVDKVDTESRAGEDANLQLEKQ--NSEIDSVSNSSLLPKNEKRDQANMPVMEKSQD 1908
+ VD + +D ++ +K+ +++ID++ + + D A + + +
Sbjct: 4506 E------SVDKDQAIEDDHDMDADKKAPDADIDAMD----VDDADADDDAQLQNGDVDAE 4555
Query: 1909 DGSVKPLGSANIDPESHLEDLISISRSYLGENTHKLSQLSVNDEELGKYHEPCDAPDHVK 1968
+ + K +G + + ++ ++ + +L Q+ + + + P
Sbjct: 4556 EVNGKNVGGFIGNRDMQDDNAQALDLDLPLQQQDELEQIIEQIDIESRADQEAAVPPRSI 4615
Query: 1969 DNATALWRRYELSTTKLSQELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKVIQFIASYY 2028
+++ LW++ E +T +L L+EQLRL+LEPT+A+KL+G YKTGKR++MK++I +IAS +
Sbjct: 4616 EDSRVLWKKSEQATDELVTVLSEQLRLILEPTLATKLRGDYKTGKRLNMKRIIPYIASQF 4675
Query: 2029 RMDKIWLRRTRPNKRDYQVVIAVDDSHSMSESCCGDVAVEALVTVCRAVSQLEMGSLAVA 2088
R DKIWLRRT+P+KR YQ++IAVDDS SMSES ++A +++ V +A++QLE G L++
Sbjct: 4676 RKDKIWLRRTKPSKRQYQIMIAVDDSKSMSESKSVELAFQSICLVSKALTQLESGGLSIV 4735
Query: 2089 SFGTKGNINLLHDFDSPFTAESGVKVSRIYTSLVFFFIDISTVHLLNMLKGSDCSFLTEE 2148
FG LH+FD F A++G KV + +
Sbjct: 4736 KFGE--TTKELHNFDQQFAADAGAKVFQWF------------------------------ 4763
Query: 2149 QMVSNLTFKQENTIADEPVVDLLKFLTNKLDAAVVKARLPSGHNPLQQLVLIIADGRFHE 2208
F++ T V + +K + + S ++ L QL ++I+DG +
Sbjct: 4764 ------GFQETKTDVKRLVAESIK---------IFERARTSQNSDLWQLQIVISDGVCED 4808
Query: 2209 KDNLKRCVREALASNRMVAFLLLD--NSQESIMDLMEASF---EGG--KMKFSKYMDSFP 2261
+ ++R VR A + M+ F+++D N++ESI+D+ + S+ + G +++ +KY+D+FP
Sbjct: 4809 HETVQRLVRRARENRIMLVFVIIDGINAKESILDMGQVSYVPDQNGVLQLQVTKYLDTFP 4868
Query: 2262 FPYYIVLRNIEALPRTLANLLRQ 2284
F +Y+V+R+I LP ++ +LRQ
Sbjct: 4869 FEFYVVVRDISELPEMISIILRQ 4891
Score = 78.2 bits (191), Expect = 3e-12
Identities = 70/299 (23%), Positives = 141/299 (46%), Gaps = 31/299 (10%)
Query: 595 ANRYNFYKDSNAHEIEQMLKVLAPLRQQITSLLNEWEEQNDLQRFLDVIDMLLTLPSDIP 654
A+ +FY + E+++ K++ L + +LL +W E L+ + L ++ P
Sbjct: 3282 ASDIDFYHGGSVVELKKSAKLIERLLYSVNNLLVQWPEHATLRELFRICKEYLEYSANTP 3341
Query: 655 LAKAFSGLQFLLHKAQVMQENHSK-FTFSNQLKSVFDLMSSWHKMELGSWPVLLDEVMDQ 713
+AK ++ + A ++ SK + S + + L+ W K+EL +W L +
Sbjct: 3342 IAKLLQKIEQIYTFAAEWEKYASKNVSLSVHIDELTRLIVEWRKLELLTWKSLFE----- 3396
Query: 714 YENNA-KKSVLSSSIHYF*SI---NFPKSNFYFSYES-----CSLEDFIQTSSFGEFRKR 764
YEN + ++++ + H + +I NF F+ + E +L F S++GE R
Sbjct: 3397 YENKSVERNIGNWWFHLYETIINANFKNVEFHGTDEEYTQLLLALNVFFSKSTYGEIHIR 3456
Query: 765 LQLLYAFLGQNHTSACLKINSSNIVFFLHCWTLQLLSDGAVNILVQYVWILCAVLTNHID 824
LQ+++AF+ H S +NS+ LH T NI Y L V+ + I
Sbjct: 3457 LQMVHAFI--KHVSV---LNSAGTPV-LHALT---------NITTFYEQFL-PVIEDSIA 3500
Query: 825 ASRKEILTELKDLVKLCRWEQDKSYSSIENLKKSRQKLKKLIKKHTDILQEPMDKLIRD 883
A++K + E+ +++ L W+ + ++ ++S L K+++K+ D+L + L+++
Sbjct: 3501 ANKKILEKEISEVILLASWKDVNVDALKQSSRRSHNNLYKILRKYRDVLATEVSPLVQN 3559
Score = 68.6 bits (166), Expect = 2e-09
Identities = 83/428 (19%), Positives = 172/428 (39%), Gaps = 59/428 (13%)
Query: 1523 TPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQSGDDSCDEGDAQNDEAAAQNEFDDE 1582
+P+ E+ E ++ +G G A+++S + +D ++ ND+ Q+E ++
Sbjct: 4049 SPEPPSEEVEDN-NLHEGTGLGDGEGAQNNSKDVEEDEDLLEDAQKPNDDQKDQDERSED 4107
Query: 1583 ENGDDVNMDKEAAHS--DATGLKPDEPDHSSDMEIDLNANEDVDPIEEGDQEGHDDSAEN 1640
E+ + V+M+ + A +A G + D + E DL+ E++D +++ D DD N
Sbjct: 4108 EDDNAVDMEGDIAGELENAPGQDSGDEDEMEEEEKDLD--EEIDDLDD-DPNAIDDKMWN 4164
Query: 1641 GNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEHQENDDMNSMDPKNDTSESSDVVNPQV 1700
E++T E+ ++ +S DD+ +E+++ N + + T+E
Sbjct: 4165 EEPEEDT------KEKESEKMPENSAADDVQASKEEDENANDNNQADGTAED-------- 4210
Query: 1701 SNVDLASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAVTGGFPSSDM----SEMDINMS 1756
+ + D + G E++ Q + H D N + P + +M+++
Sbjct: 4211 ------GREEDDAEEDGEEDVGEQDD-EVKHED--NEDLEANVPEVETMDLPEDMNLDSG 4261
Query: 1757 DSSNTGGFSKTQPKSHLPQHEHSFSQEKQTNPSRSTGDALDFRKEKINVSGDLPEDNIEH 1816
D ++ + Q + E ++E +T + + E ++ + +D I
Sbjct: 4262 DEKDSDDGADDQFDDDMSVDEEPNAEEMETKDDAIDENNMGSDDEALSPEEEQQDDGIAE 4321
Query: 1817 HGE--------------MDDNNADEYGYVSEFEKGTTQALGPAT------LEQVDRNIDV 1856
GE D N+ DE E A A LE ++ DV
Sbjct: 4322 DGEAASDEEADGAEEEGQDQNSEDELAEDHADENKQEPADQEAASDKQQGLEGIEDLADV 4381
Query: 1857 DKVDTESRAGEDANLQLE----KQNSEIDSVSNSSLLPKNEKRDQANMPVMEKSQDDG-- 1910
+D E+ + A E + E D+V +S + +E++ V + S+++
Sbjct: 4382 QDIDMEAAVEQHAGASGEGAEAADSKEQDNVGSSGMAQSHEQQQDNGEEVQDSSREEAIE 4441
Query: 1911 SVKPLGSA 1918
S+K LG +
Sbjct: 4442 SLKQLGDS 4449
>UniRef100_UPI000043035A UPI000043035A UniRef100 entry
Length = 5037
Score = 272 bits (695), Expect = 1e-70
Identities = 251/936 (26%), Positives = 426/936 (44%), Gaps = 163/936 (17%)
Query: 1449 KKEEQEESKEVPGNDNTGIEMDQDFQADAVSLSE--DSSENEDCDGENEELESEMGPTGP 1506
K+++ + +E +D IE D Q + S E D E+ED + EEL+ E+
Sbjct: 4157 KEKDDGDEEEEENDDAVDIEGDMAGQLEEASDQEKDDDKEDEDHSDDKEELDEEIDDIDD 4216
Query: 1507 -DSEAVGEKIWDQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQSGDDSCDE 1565
D A+ EK+WD+ E +D EK +S ++ + ++ E+ A +D ++ D D
Sbjct: 4217 LDPNAIDEKMWDE---EVKEDKKEK-DSDKLPENSNNNDDEMEAMEDEENETKPKDK-DN 4271
Query: 1566 GDAQNDEAAAQNEFDDEENGDDVNMDKEAAHSDATGLKPDEPD------HSSDMEIDLNA 1619
D Q + + E +E +GDD D++ +K +E D H + E L+
Sbjct: 4272 NDNQEGDDNEKEEQREENDGDDDEEDEKDVGEQEDDVKNNEDDNEKLEDHVPETET-LDL 4330
Query: 1620 NEDVDPIEEGDQEGHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEHQENDD 1679
ED++ +E + +G ++ E ++ D+ D M+ D + +D G+E +E+DD
Sbjct: 4331 PEDMNLDDEDEMKGEEEEEEGQDKFDDNLDDDIEMK------DDDEKSNDNGEEEEEDDD 4384
Query: 1680 M----NSMDPKNDTS-----ESSDVV-----NPQVSNVDLASQSKSDLQTSGSENIA--- 1722
N MDP N+ E DV N +++ + S ++ D+ +E
Sbjct: 4385 DHQQDNEMDPTNEEEQLPEDEGGDVDDEFNGNNEINEDVMESDNEDDVVGEDNEKPLYEN 4444
Query: 1723 SQSNLSNSHHDFGNPAVTGGFPSSDMSEMDINMS-------------------DSSNTGG 1763
+ N + + P G ++D+ D +M + +N G
Sbjct: 4445 EEGGNDNDNDEDEEPTAEGVEGANDIDTEDADMDSAVKQESGEKGEGADNQVMEENNDIG 4504
Query: 1764 FSKTQPKSHLPQHEHSFSQEKQTNPS-------------RSTGDAL-DFRKEKINVSGDL 1809
S T Q + E++ + S + GD+L +F + + + +
Sbjct: 4505 ASGTATTMDQQQQQQQQKSEEEEDKSVQDDAREKANESLKQLGDSLKEFHRRRQEIMDVI 4564
Query: 1810 PEDNIEHHGEMD---DNNADEYGYVS-EFEKGTTQALGPATLEQVDRNIDVDK-VDTESR 1864
++ E E + + DE+ +V E TQALG A +QV ++ID DK +D E
Sbjct: 4565 KQEQPEEKEEENSAKNTKPDEFQHVDGENADFDTQALGAADKDQV-QSIDEDKAIDDEE- 4622
Query: 1865 AGEDANLQLEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKSQDDGSVKPLGSANIDPES 1924
E+AN Q + + E D + KNE D ++ DG + + E
Sbjct: 4623 --ENANHQEDIEIKEEDEI-------KNEDEDDLESGEIKDENPDGDFEGEAKSAFMGER 4673
Query: 1925 HLED--------LISISRSYLGENTHKLSQLSVNDEELG-KYHEPCDAPDHVKDNATALW 1975
+ D +IS + E H++ + +D+ + + E + P + A LW
Sbjct: 4674 KITDNLDDDDDMMISNELNDEEEEEHEMEDDASDDDLIPMELDEINNIPPIELEIARKLW 4733
Query: 1976 RRYELSTTKLSQELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKVIQFIASYYRMDKIWL 2035
+ +L+T +L+ L EQLRL+LEPT+A+KL+G YKTGKR++MK++I +IAS ++ DKIWL
Sbjct: 4734 KNSDLATQELASGLCEQLRLILEPTLATKLRGDYKTGKRLNMKRIIPYIASDFKKDKIWL 4793
Query: 2036 RRTRPNKRDYQVVIAVDDSHSMSESCCGDVAVEALVTVCRAVSQLEMGSLAVASFGTKGN 2095
RRT+P+KR YQ++IAVDDS SMSES ++A ++ V +A+SQLE G L++ FG +
Sbjct: 4794 RRTKPSKRQYQIMIAVDDSKSMSESKSTELAFHSIALVSKALSQLESGGLSIVRFGE--D 4851
Query: 2096 INLLHDFDS-PF--TAESGVKVSRIYTSLVFFFIDISTVHLLNMLKGSDCSFLTEEQMVS 2152
+ ++ F++ PF + E G K +F + D +D L E +
Sbjct: 4852 VKVVQSFNNKPFNNSQEMGAK--------IFQWFDFQQTK-------TDMKLLCNESLKI 4896
Query: 2153 NLTFKQENTIADEPVVDLLKFLTNKLDAAVVKARLPSGHNPLQQLVLIIADGRFHEKDNL 2212
K + + + +N L QL +I++DG + + +
Sbjct: 4897 FQDAKANGSSSSS-----------------------TTNNDLWQLQIILSDGVCEDHETI 4933
Query: 2213 KRCVREALASNRMVAFLLLD------------------NSQESIMDLMEASF------EG 2248
R VR+A M+ F+++D ESIMD+ + S+ G
Sbjct: 4934 LRMVRKAREEKIMMVFVIIDGITTTTTTTTSGTSGTTTGKHESIMDMQQVSYVTDNNTGG 4993
Query: 2249 GKMKFSKYMDSFPFPYYIVLRNIEALPRTLANLLRQ 2284
+K KY+DSFPF +Y+V++NI+ LP LA +LRQ
Sbjct: 4994 MVLKVDKYLDSFPFEFYVVVKNIQELPEMLALILRQ 5029
Score = 79.3 bits (194), Expect = 1e-12
Identities = 159/772 (20%), Positives = 304/772 (38%), Gaps = 125/772 (16%)
Query: 126 IGCAWAHIGALRIHLLLSYNEVDPVMKYYCKYTQLEET-------ISSLELEIQVRKECG 178
+G AW I L + + DP +K Y Y E+ ISS E +V
Sbjct: 2919 LGKAWVSFSLGLILLYVPDSPYDPAIKEYVLYKVFEDRKVFGGNLISSWESARRV----- 2973
Query: 179 YLSGQFLTVEADKRK-AERLEKLQAELRKLQRKIVFRSESWKYKKLMNECDEFLKH---I 234
DK E K +L V+R +S L +E + ++ +
Sbjct: 2974 --------FSGDKEMYLESTLKHLIDLEAPNNPKVYR-DSKSIDGLFDEWNSIMESTIDM 3024
Query: 235 ASLEVLVGNVEAEDLQQVIDRTHSWQETAMCFINRLTDEYTAYNDIIQPIQVAVYEMKFG 294
+E L+ +V +Q ++ +Q FI RL Y Y+D+ + +Y MK G
Sbjct: 3025 GPVESLLKSVFTSS-EQGVNMMEMFQNNTSQFIMRLKKNYLLYSDLDDILCGYIYGMKLG 3083
Query: 295 LSLVLSSFLEKEYLR-KVGHENINLVTDMIYILMRFPRAASWKFISVEDVGVDLHSSYKL 353
++ + +YL + ++ T + + FP + + V +D S
Sbjct: 3084 FEMITIDKNQGKYLYPQTWSIDVCDFTSLKSVERVFPSVQDF----AKTVSID---SSAA 3136
Query: 354 DFGTDFYLNMGLIERLITLSSGVSADKKVSAMRCRASIYWNILVQIAYSIANAKIIDRES 413
+F +++ +G R S +++ + SI L + Y +
Sbjct: 3137 EFVMAYFIKLGFAHRS-------SENEQQQKQQQTQSILIQSLQTLYYRWS--------- 3180
Query: 414 YMLLHKIFDEFASLWMSMKVYAKSKSDHDAQQFKFKPRAFQIESIMELEIPALANSSATE 473
L +I +E +L +Y + D D + FK E + L+I N++ +
Sbjct: 3181 ---LRRIKEEKENLQQG-SLYKYNDPDEDIEG-DFKQLFPDYEDV--LDIDGTTNANTLK 3233
Query: 474 AFSDWKEFSYEEKSADNMESSEECEILDEEWKHLEESILDNVVLIHSQLFGSGDLVQAPG 533
+ E YE ++D ++ E L +E ++S++D ++H +L+
Sbjct: 3234 KNNASFESIYESIASDYIK-----EYLLQE----KDSVID---IVHQ----GSELITHLN 3277
Query: 534 IFEISDEDRLHSFSESYKLGINLIKGAHSSNLASLDAKLIPEHLFYLSIDYRRKFHSSSK 593
+E + YK+ N +S + SL +L H + ++
Sbjct: 3278 QYE----------NNLYKISNN------ASMITSLVNELANTHTKF------------NQ 3309
Query: 594 SANRYNFYKDSNAHEIEQMLKVLAPLRQQITSLLNEWEEQNDLQRFLDVIDMLLTLPSDI 653
+ + +NFY+DSN E+++ + ++ + LL++W E L+ + + L+ P +
Sbjct: 3310 AVSDFNFYQDSNPTEVKRAVTIMTTVYNLSKKLLDQWPEHATLKNIVFATNEFLSYPIGL 3369
Query: 654 PLAKAFSGL-QFLLHKAQVMQENHSKFTFSNQLKSVFDLMSSWHKMELGSWPVLLDEVMD 712
PL + L Q A+ + S+ + +Q + +L+ SW K+EL +W L +
Sbjct: 3370 PLGRYLQKLEQIYTFIAEWQKYASSQVSLEDQFVVLTNLIVSWRKLELSTWKSLFEFEEK 3429
Query: 713 QYENNAKK---SVLSSSIHYF*SINFPKSNFYFSYESCSLEDFIQTSSFGEFRKRLQLLY 769
E N K +L I N + +L F+ + GEF RL+LL
Sbjct: 3430 SVEKNIGKWWFYLLEIIIIPMLGDNEKEPAVTLL---SALNVFMSKVTCGEFTIRLKLLK 3486
Query: 770 AFLGQNHTSACLKINSSNIVFFLHCWTLQLLSDGAVNILVQYVWILCAVLTNHIDASRKE 829
AF +NH +IN ++ + D N + Y VL+ I+ S+K
Sbjct: 3487 AF--KNHA---FEINKTHPIV-----------DALCNFVTFYEQFQPTVLST-IEDSKKR 3529
Query: 830 ILTELKDLVKLCRWEQDKSYSSIENLKKSRQKLKKLIKKHTDILQEPMDKLI 881
+ ++ +++ L W+ + ++ ++S L K+++K+ IL P+ +I
Sbjct: 3530 LEKDINEVILLASWKDVNIDALKQSARRSHNNLYKIVRKYRAILSTPVQPII 3581
Score = 77.4 bits (189), Expect = 5e-12
Identities = 101/455 (22%), Positives = 184/455 (40%), Gaps = 70/455 (15%)
Query: 1523 TPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQSGDDSCDEGDAQNDEAAAQNEFDDE 1582
TP+ E+ + ++ DG G A+++S + +D ++ N+E +++ D+E
Sbjct: 4106 TPEAPNEQKDDNTNLHDGTGLGDGEGAQNNSNDVEDDEDLSEQAQQPNEENKEKDDGDEE 4165
Query: 1583 ENGDDVNMD---------KEAAHSDATGLKPDEPDHSSD---MEIDLNANEDVDP----- 1625
E +D +D +EA+ + K DE DHS D ++ +++ +D+DP
Sbjct: 4166 EEENDDAVDIEGDMAGQLEEASDQEKDDDKEDE-DHSDDKEELDEEIDDIDDLDPNAIDE 4224
Query: 1626 -------IEEGDQEGHDDSAENGNQEDETCPPDEIMEEAHTEV-------DVSSEKDDLG 1671
E+ ++ D EN N D+ E ME+ E + + E DD
Sbjct: 4225 KMWDEEVKEDKKEKDSDKLPENSNNNDDEM---EAMEDEENETKPKDKDNNDNQEGDDNE 4281
Query: 1672 QEHQ--ENDDMNSMDPKNDTSESSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSN 1729
+E Q END + + + D E D V +N D + + + + + ++ NL +
Sbjct: 4282 KEEQREENDGDDDEEDEKDVGEQEDDVK---NNEDDNEKLEDHVPETETLDLPEDMNLDD 4338
Query: 1730 SHHDFGNPAVTGGFPS-SDMSEMDINMSD----SSNTGGFSKTQPKSHLPQHEHSFSQEK 1784
G G D + DI M D S++ G + H +E + E+
Sbjct: 4339 EDEMKGEEEEEEGQDKFDDNLDDDIEMKDDDEKSNDNGEEEEEDDDDHQQDNEMDPTNEE 4398
Query: 1785 QTNPSRSTGDALDFRKEKINVSGDLPEDNIEHHGEMDDNNADEYGYVSEFEKG----TTQ 1840
+ P GD D + N + ++ ED +E E D D + E E+G
Sbjct: 4399 EQLPEDEGGDVDD----EFNGNNEINEDVMESDNEDDVVGEDNEKPLYENEEGGNDNDND 4454
Query: 1841 ALGPATLEQVDRNIDVDKVDTE---------SRAGEDANLQLEKQNSEIDSVSNSSLLPK 1891
T E V+ D+D D + GE A+ Q+ ++N++I + ++ + +
Sbjct: 4455 EDEEPTAEGVEGANDIDTEDADMDSAVKQESGEKGEGADNQVMEENNDIGASGTATTMDQ 4514
Query: 1892 NEKRDQANMPVMEKS--QDDG------SVKPLGSA 1918
+++ Q E QDD S+K LG +
Sbjct: 4515 QQQQQQQKSEEEEDKSVQDDAREKANESLKQLGDS 4549
>UniRef100_Q9NU22 Midasin [Homo sapiens]
Length = 5596
Score = 271 bits (693), Expect = 2e-70
Identities = 251/931 (26%), Positives = 413/931 (43%), Gaps = 152/931 (16%)
Query: 1450 KEEQEESKEVPGNDNTGIEMDQDFQADAVS--LSEDSSENEDCDGENEELESEMGP-TGP 1506
KE+ + ++ G DN IEM +DF L E ++E D E +L+ MG G
Sbjct: 4711 KEDPDSKSDIKGEDNA-IEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGE 4769
Query: 1507 DSEAVGEKIW---DQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQSGDDSC 1563
+++ + E++W D+ EDE +D + E+GP + + D EL AKDD+ SG+ +
Sbjct: 4770 EADKLDERLWGDDDEEEDEEEEDNKTE-ETGPGMDEEDS---ELVAKDDNLD--SGNSNK 4823
Query: 1564 DEGDAQNDEAAAQNEFDDEENGDD-VNMDKEAAHSDATGLKP--------------DEPD 1608
D+ E + E DD G+D +N + D + P D PD
Sbjct: 4824 DKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPD 4883
Query: 1609 HSSDMEIDLNANEDVDPIEEGDQE------------GH----------DDSAENGNQEDE 1646
+ D N ED D EEG++E GH D + QE E
Sbjct: 4884 DLNLDSEDKNGGEDTDN-EEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPE 4942
Query: 1647 TCPPDEIMEEAHTEVDVSSEKDDLG-----QEHQENDDMNSMDPKNDTSESSDVVNPQVS 1701
P ++ E E+D ++ D +EH E + + + E P +
Sbjct: 4943 EGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGP--A 5000
Query: 1702 NVDLASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAV-----------TGGFPSSDMSE 1750
+ Q + + + S +E ++ H G V G P + +
Sbjct: 5001 DQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGK 5060
Query: 1751 -------MDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEK-QTNPSRSTGDALDFRKEK 1802
D N ++ + ++ + H ++ SF ++ Q + RS GD + ++
Sbjct: 5061 EEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKR 5120
Query: 1803 INV--SGDLPEDNIEHHGEMDDNNADEYGYVSEFEKG-TTQALGPATLEQVDRNIDVDKV 1859
+ + E + +AD + ++ + Q A+ EQ D K
Sbjct: 5121 LRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGK- 5179
Query: 1860 DTESRAGEDANLQLEKQNSEIDSVSNSSLLPKNEKR--------DQANMPVM----EKSQ 1907
D E ED + E+Q E + L P+ K D+ + + E+ Q
Sbjct: 5180 DQEEEEIEDTLMDTEEQE-EFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQ 5238
Query: 1908 DDGSVKP-LGSANIDPESHLEDLISISRSYLGENTHKLSQLSVND--EELGKYHE---PC 1961
D + K + N PE E I + +L + + VN+ +EL + E P
Sbjct: 5239 DPRTDKAHKETENEKPERSRESTIHTAHQFLMDTIFQPFLKDVNELRQELERQLEMWQPR 5298
Query: 1962 DAPDHVKDNATA-LWRRYELSTTKLSQELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKV 2020
++ + ++ A +W+ Y + T LSQ L E+LRL+LEPT A+KL+G Y+TGKR++++KV
Sbjct: 5299 ESGNPEEEKVAAEMWQSYLILTAPLSQRLCEELRLILEPTQAAKLKGDYRTGKRLNIRKV 5358
Query: 2021 IQFIASYYRMDKIWLRRTRPNKRDYQVVIAVDDSHSMSESCCGDVAVEALVTVCRAVSQL 2080
I +IAS +R DKIWLRRT+P+KR YQ+ +A+DDS SM ++ +A E+L + A++ L
Sbjct: 5359 IPYIASQFRKDKIWLRRTKPSKRQYQICLAIDDSSSMVDNHTKQLAFESLAVIGNALTLL 5418
Query: 2081 EMGSLAVASFGTKGNINLLHDFDSPFTAESGVKVSRIYTSLVFFFIDISTVHLLNMLKGS 2140
E+G +AV SFG ++ LLH F F+ SG ++ R+
Sbjct: 5419 EVGQIAVCSFGE--SVKLLHPFHEQFSDYSGSQILRL----------------------- 5453
Query: 2141 DCSFLTEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLDAAVVKARLPSGHNPLQQLVLI 2200
F+Q+ T + L+ + N AA ++ S QL+L+
Sbjct: 5454 -------------CKFQQKKT----KIAQFLESVANMFAAAQQLSQNISSETA--QLLLV 5494
Query: 2201 IADGR---FHEKDNLKRCVREALASNRMVAFLLLDN--SQESIMDLMEASFEG-GKM-KF 2253
++DGR K+ + V+ A +N V F++LDN S++SI+D+ F+G G+M +
Sbjct: 5495 VSDGRGLFLEGKERVLAAVQAARNANIFVIFVVLDNPSSRDSILDIKVPIFKGPGEMPEI 5554
Query: 2254 SKYMDSFPFPYYIVLRNIEALPRTLANLLRQ 2284
YM+ FPFPYYI+LR++ ALP TL++ LRQ
Sbjct: 5555 RSYMEEFPFPYYIILRDVNALPETLSDALRQ 5585
Score = 170 bits (431), Expect = 4e-40
Identities = 187/853 (21%), Positives = 335/853 (38%), Gaps = 120/853 (14%)
Query: 127 GCAWAHIGALRIHLLLSYNEVDPVMKYYCKYTQLEETISSLELEIQVRKECGYLSGQFLT 186
G W +G L+I L DP +K K ++E + L+ E + R LS Q T
Sbjct: 3221 GSLWVSLGLLQIQTWLPQARFDPAVKREYKLNYVKEELHQLQCEWKTRN----LSSQLQT 3276
Query: 187 ----------------VEADKRKAERLEKLQAELRKLQRKIVFRSESWKYKKLMNECDEF 230
V +++ +RL+ L L K Q FR + Y+ L+ E +
Sbjct: 3277 GRDLEDEVVVSYSHPHVRLLRQRMDRLDNLTCHLLKKQ---AFRPQLPAYESLVQEIHHY 3333
Query: 231 LKHIASLEVLV-------------GNVEAEDLQQVIDRTHSWQETAMCFINRLTDEYTAY 277
+ IA + G A+ Q ++ SWQ++ F RL++EYT Y
Sbjct: 3334 VTSIAKAPAVQDLLTRLLQALHIDGPRSAQVAQSLLKEEASWQQSHHQFRKRLSEEYTFY 3393
Query: 278 NDIIQPIQVAVYEMKFGLSLVLSSFLEKEYLRKVGHENINLVTDMIYILMRFPRAASW-- 335
D + P+Q ++ +++ G+ LV S + VG + + + L+ FP
Sbjct: 3394 PDAVSPLQASILQLQHGMRLVASELHTSLHSSMVGADRLGTLATA---LLAFPSVGPTFP 3450
Query: 336 KFISVEDVGVDLHSSYKLDFGTDFYLNMGLIERLITLSSGVSADKK-VSAMRCRASIYWN 394
+ + D + S L GL + ++ S G + K A R + N
Sbjct: 3451 TYYAHADTLCSVKSEEVL---------RGLGKLILKRSGGKELEGKGQKACPTREQLLMN 3501
Query: 395 ILVQIAYSIANAKIIDRESYMLLHKIFDEFASLWMSMKVYAKSKSDHDAQQFKFKPRAFQ 454
L+ + + +D+ + L + E S W + A+ K++ ++ ++++ R +
Sbjct: 3502 ALLYLRSHVLCKGELDQRALQLFRHVCQEIISEWDEQERIAQEKAEQESGLYRYRSRNSR 3561
Query: 455 IESIMELEIPALANSSATEAFSDWKEFSYEEKSADNMESSEECEILDEEWKH---LEESI 511
E E D+ + + +N +S+ E +E + L ++
Sbjct: 3562 TALSEEEEEEREFRKQFPLHEKDFADILVQPTLEENKGTSDGQE--EEAGTNPALLSQNS 3619
Query: 512 LDNVVLIHSQLF--GSGDLVQAPGIFEISDEDRLHSFSESYKLGINLIKGAHSSNLASLD 569
+ V+LIH QL + L + + L F Y+ G +L+ + L+
Sbjct: 3620 MQAVMLIHQQLCLNFARSLWYQQTLPPHEAKHYLSLFLSCYQTGASLVTHFYPLMGVELN 3679
Query: 570 AKLIPEHLFYLSIDYRRKFHSSS-----KSANRYNFYKDSNAHEIEQMLKVLAPLRQQIT 624
+L+ L ++ + F + K Y+FY+ N E Q VL + ++
Sbjct: 3680 DRLLGSQLLACTLSHNTLFGEAPSDLMVKPDGPYDFYQHPNVPEARQCQPVLQGFSEAVS 3739
Query: 625 SLLNEWEEQNDLQRFLDVIDMLLTLPSDIPLAKAFSGLQFLLHKAQVMQENHSK-FTFSN 683
LL +W E L++ L V+D + + P P++K +GL+ LL KAQ +EN S+ +
Sbjct: 3740 HLLQDWPEHPALEQLLVVMDRIRSFPLSSPISKFLNGLEILLAKAQDWEENASRALSLRK 3799
Query: 684 QLKSVFDLMSSWHKMELGSWPVLLDEVMDQYENNAKKSVLSSSIHYF*SINFPKSNFYFS 743
L + ++ W K+EL W + LD M ++ + K H+F + +
Sbjct: 3800 HLDLISQMIIRWRKLELNCWSMSLDNTMKRHTEKSTK-------HWFSIYQMLEKHMQEQ 3852
Query: 744 YES-------------CSLEDFIQTSSFGEFRKRLQLLYAFLGQNHTSACLKINSSNIVF 790
E +L+ FI+ SS GEF RLQ+L F
Sbjct: 3853 TEEQEDDKQMTLMLLVSTLQAFIEGSSLGEFHVRLQMLLVF------------------- 3893
Query: 791 FLHCWTLQLLSDGAVNILVQYVWILCAVLTNHIDASRKEIL-------TELKDLVKLCRW 843
HC L + + L +W L D + +I+ ELK+ VK+ +W
Sbjct: 3894 --HCHVLLMPQVEGKDSLCSVLWNLYHYYKQFFDRVQAKIVELRSPLEKELKEFVKISKW 3951
Query: 844 EQDKSYSSIENLKKSRQKLKKLIKKHTDILQEPMDKLI--------RDVLHKGSISGVSD 895
+S ++++K+ + L K +KK +L EP + D L + + S+
Sbjct: 3952 NDVSFWSIKQSVEKTHRTLFKFMKKFEAVLSEPCRSSLVESDKEEQPDFLPRPTDGAASE 4011
Query: 896 LPLFSDENRLYQE 908
L + NR +E
Sbjct: 4012 LSSIQNLNRALRE 4024
Score = 56.2 bits (134), Expect = 1e-05
Identities = 74/335 (22%), Positives = 130/335 (38%), Gaps = 47/335 (14%)
Query: 1520 EDETPDDTGEKYESGPSVKDGDGSNKELRAKD-DSTSDQSGDDSCDE---------GDAQ 1569
E E D ++ + V+D +E +D DS SD G+D+ E D +
Sbjct: 4682 EGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGE 4741
Query: 1570 NDEAAAQNEFDDEENGDDVNMDKEAAHSDATGLKPD--------EPDHSSDMEIDLNANE 1621
+E +E D E GD +DK D G + D + D D E + N E
Sbjct: 4742 LEEQEEDDEKSDSEGGD---LDKHM--GDLNGEEADKLDERLWGDDDEEEDEEEEDNKTE 4796
Query: 1622 DVDP-IEEGDQE--GHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSE-KDDLGQEHQEN 1677
+ P ++E D E DD+ ++GN + D+ E+ E D + +D + ++ E
Sbjct: 4797 ETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDER 4856
Query: 1678 D-DMNSMDPKNDTSESSDVVNPQVSNVDLASQSKSDLQ-TSGSENIASQSNLSNSHHDFG 1735
D D N +DP + E P+ +DL D + +G E+ ++ + +
Sbjct: 4857 DYDENEVDPYHGNQEKV----PEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIK 4912
Query: 1736 NPAVTGGFPSSDMSEMDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEK-QTNPSRSTGD 1794
G + + E + + ++S S +P+ + + + +E+ T GD
Sbjct: 4913 EKPEEAGHEAEERGETETDQNESQ-----SPQEPEEGPSEDDKAEGEEEMDTGADDQDGD 4967
Query: 1795 ALDFRKEKINVSGDLPEDNIEHHGEMDDNNADEYG 1829
A +E + + E D ADE G
Sbjct: 4968 AAQHPEEH--------SEEQQQSVEEKDKEADEEG 4994
>UniRef100_UPI000042CC69 UPI000042CC69 UniRef100 entry
Length = 1184
Score = 270 bits (690), Expect = 4e-70
Identities = 250/935 (26%), Positives = 426/935 (44%), Gaps = 167/935 (17%)
Query: 1448 QKKEEQEESKEVPGNDNTGIEMDQDFQADAVSLSEDSSENEDCDGENEELESEMGPTGP- 1506
+++EE +++ ++ G+ +E D + D D E+ED + EEL+ E+
Sbjct: 311 EEEEENDDAVDIEGDMAGQLEEASDQEKD------DDKEDEDHSDDKEELDEEIDDIDDL 364
Query: 1507 DSEAVGEKIWDQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQSGDDSCDEG 1566
D A+ EK+WD +E +D EK +S ++ + ++ E+ A +D ++ D D
Sbjct: 365 DPNAIDEKMWD---EEVKEDKKEK-DSDKLPENSNNNDDEMEAMEDEENETKPKDK-DNN 419
Query: 1567 DAQNDEAAAQNEFDDEENGDDVNMDKEAAHSDATGLKPDE------PDHSSDMEIDLNAN 1620
D Q + + E +E +GDD D++ +K +E DH + E L+
Sbjct: 420 DNQEGDDNEKEEQREENDGDDDEEDEKDVGEQEDDVKNNEDDNEKLEDHVPETE-TLDLP 478
Query: 1621 EDVDPIEEGDQEGHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSEKDDLGQEHQENDD- 1679
ED++ +E + +G ++ E ++ D+ D M+ D + +D G+E +E+DD
Sbjct: 479 EDMNLDDEDEMKGEEEEEEGQDKFDDNLDDDIEMK------DDDEKSNDNGEEEEEDDDD 532
Query: 1680 ---MNSMDPKND-----TSESSDV-----VNPQVSNVDLASQSKSDLQTSGSENIA---S 1723
N MDP N+ E DV N +++ + S ++ D+ +E
Sbjct: 533 HQQDNEMDPTNEEEQLPEDEGGDVDDEFNGNNEINEDVMESDNEDDVVGEDNEKPLYENE 592
Query: 1724 QSNLSNSHHDFGNPAVTGGFPSSDMSEMDINMS-------------------DSSNTGGF 1764
+ N + + P G ++D+ D +M + +N G
Sbjct: 593 EGGNDNDNDEDEEPTAEGVEGANDIDTEDADMDSAVKQESGEKGEGADNQVMEENNDIGA 652
Query: 1765 SKTQPKSHLPQHEHSFSQEKQTNPS-------------RSTGDAL-DF---RKEKINVSG 1807
S T Q + E++ + S + GD+L +F R+E ++V
Sbjct: 653 SGTATTMDQQQQQQQQKSEEEEDKSVQDDAREKANESLKQLGDSLKEFHRRRQEIMDVIK 712
Query: 1808 DLPEDNIEHHGEMDDNNADEYGYV-SEFEKGTTQALGPATLEQVDRNIDVDK-VDTESRA 1865
+ E + DE+ +V E TQALG A +QV ++ID DK +D E
Sbjct: 713 QEQPEEKEEENSAKNTKPDEFQHVDGENADFDTQALGAADKDQV-QSIDEDKAIDDEE-- 769
Query: 1866 GEDANLQLEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKSQDDGSVKPLGSANIDPESH 1925
E+AN Q + + E D + KNE D ++ DG + + E
Sbjct: 770 -ENANHQEDIEIKEEDEI-------KNEDEDDLESGEIKDENPDGDFEGEAKSAFMGERK 821
Query: 1926 LED--------LISISRSYLGENTHKLSQLSVNDEELG-KYHEPCDAPDHVKDNATALWR 1976
+ D +IS + E H++ + +D+ + + E + P + A LW+
Sbjct: 822 ITDNLDDDDDMMISNELNDEEEEEHEMEDDASDDDLIPMELDEINNIPPIELEIARKLWK 881
Query: 1977 RYELSTTKLSQELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKVIQFIASYYRMDKIWLR 2036
+L+T +L+ L EQLRL+LEPT+A+KL+G YKTGKR++MK++I +IAS ++ DKIWLR
Sbjct: 882 NSDLATQELASGLCEQLRLILEPTLATKLRGDYKTGKRLNMKRIIPYIASDFKKDKIWLR 941
Query: 2037 RTRPNKRDYQVVIAVDDSHSMSESCCGDVAVEALVTVCRAVSQLEMGSLAVASFGTKGNI 2096
RT+P+KR YQ++IAVDDS SMSES ++A ++ V +A+SQLE G L++ FG ++
Sbjct: 942 RTKPSKRQYQIMIAVDDSKSMSESKSTELAFHSIALVSKALSQLESGGLSIVRFGE--DV 999
Query: 2097 NLLHDFDS-PF--TAESGVKVSRIYTSLVFFFIDISTVHLLNMLKGSDCSFLTEEQMVSN 2153
++ F++ PF + E G K +F + D +D L E +
Sbjct: 1000 KVVQSFNNKPFNNSQEMGAK--------IFQWFDFQQTK-------TDMKLLCNESLKIF 1044
Query: 2154 LTFKQENTIADEPVVDLLKFLTNKLDAAVVKARLPSGHNPLQQLVLIIADGRFHEKDNLK 2213
K + + + +N L QL +I++DG + + +
Sbjct: 1045 QDAKANGSSSSS-----------------------TTNNDLWQLQIILSDGVCEDHETIL 1081
Query: 2214 RCVREALASNRMVAFLLLD------------------NSQESIMDLMEASF------EGG 2249
R VR+A M+ F+++D ESIMD+ + S+ G
Sbjct: 1082 RMVRKAREEKIMMVFVIIDGITTTTTTTTSGTSGTTTGKHESIMDMQQVSYVTDNNTGGM 1141
Query: 2250 KMKFSKYMDSFPFPYYIVLRNIEALPRTLANLLRQ 2284
+K KY+DSFPF +Y+V++NI+ LP LA +LRQ
Sbjct: 1142 VLKVDKYLDSFPFEFYVVVKNIQELPEMLALILRQ 1176
Score = 77.4 bits (189), Expect = 5e-12
Identities = 101/455 (22%), Positives = 184/455 (40%), Gaps = 70/455 (15%)
Query: 1523 TPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQSGDDSCDEGDAQNDEAAAQNEFDDE 1582
TP+ E+ + ++ DG G A+++S + +D ++ N+E +++ D+E
Sbjct: 253 TPEAPNEQKDDNTNLHDGTGLGDGEGAQNNSNDVEDDEDLSEQAQQPNEENKEKDDGDEE 312
Query: 1583 ENGDDVNMD---------KEAAHSDATGLKPDEPDHSSD---MEIDLNANEDVDP----- 1625
E +D +D +EA+ + K DE DHS D ++ +++ +D+DP
Sbjct: 313 EEENDDAVDIEGDMAGQLEEASDQEKDDDKEDE-DHSDDKEELDEEIDDIDDLDPNAIDE 371
Query: 1626 -------IEEGDQEGHDDSAENGNQEDETCPPDEIMEEAHTEV-------DVSSEKDDLG 1671
E+ ++ D EN N D+ E ME+ E + + E DD
Sbjct: 372 KMWDEEVKEDKKEKDSDKLPENSNNNDDEM---EAMEDEENETKPKDKDNNDNQEGDDNE 428
Query: 1672 QEHQ--ENDDMNSMDPKNDTSESSDVVNPQVSNVDLASQSKSDLQTSGSENIASQSNLSN 1729
+E Q END + + + D E D V +N D + + + + + ++ NL +
Sbjct: 429 KEEQREENDGDDDEEDEKDVGEQEDDVK---NNEDDNEKLEDHVPETETLDLPEDMNLDD 485
Query: 1730 SHHDFGNPAVTGGFPS-SDMSEMDINMSD----SSNTGGFSKTQPKSHLPQHEHSFSQEK 1784
G G D + DI M D S++ G + H +E + E+
Sbjct: 486 EDEMKGEEEEEEGQDKFDDNLDDDIEMKDDDEKSNDNGEEEEEDDDDHQQDNEMDPTNEE 545
Query: 1785 QTNPSRSTGDALDFRKEKINVSGDLPEDNIEHHGEMDDNNADEYGYVSEFEKG----TTQ 1840
+ P GD D + N + ++ ED +E E D D + E E+G
Sbjct: 546 EQLPEDEGGDVDD----EFNGNNEINEDVMESDNEDDVVGEDNEKPLYENEEGGNDNDND 601
Query: 1841 ALGPATLEQVDRNIDVDKVDTE---------SRAGEDANLQLEKQNSEIDSVSNSSLLPK 1891
T E V+ D+D D + GE A+ Q+ ++N++I + ++ + +
Sbjct: 602 EDEEPTAEGVEGANDIDTEDADMDSAVKQESGEKGEGADNQVMEENNDIGASGTATTMDQ 661
Query: 1892 NEKRDQANMPVMEKS--QDDG------SVKPLGSA 1918
+++ Q E QDD S+K LG +
Sbjct: 662 QQQQQQQKSEEEEDKSVQDDAREKANESLKQLGDS 696
>UniRef100_UPI000036FA32 UPI000036FA32 UniRef100 entry
Length = 4063
Score = 269 bits (687), Expect = 9e-70
Identities = 252/933 (27%), Positives = 417/933 (44%), Gaps = 152/933 (16%)
Query: 1448 QKKEEQEESK-EVPGNDNTGIEMDQDFQADAVSLS-EDSSENEDCDGENEELESEMGP-T 1504
Q+K++ +SK ++ G DN IEM +DF E+ ++E D E +L+ MG
Sbjct: 3176 QEKDKDPDSKSDIKGEDNA-IEMSEDFDGKMHDGELEEQEDDEKSDSEGGDLDKHMGDLN 3234
Query: 1505 GPDSEAVGEKIW---DQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQSGDD 1561
G +++ + E++W D+ EDE +D + E+GP + + D EL AKDD+ SG+
Sbjct: 3235 GEEADKLDERLWGDDDEEEDEEEEDNKTE-ETGPGMDEEDS---ELVAKDDNLD--SGNS 3288
Query: 1562 SCDEGDAQNDEAAAQNEFDDEENGDD-VNMDKEAAHSDATGLKP--------------DE 1606
+ D+ E + E DD G+D +N + D + P D
Sbjct: 3289 NKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDEREYDENEVDPYHGNQEKVPEPEALDL 3348
Query: 1607 PDHSSDMEIDLNANEDVDPIEEGDQE------------GH----------DDSAENGNQE 1644
PD + D N ED D EEG++E GH D + QE
Sbjct: 3349 PDDLNLDSEDKNGGEDTDN-EEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQE 3407
Query: 1645 DETCPPDEIMEEAHTEVDVSSEKDDLG-----QEHQENDDMNSMDPKNDTSESSDVVNPQ 1699
E P ++ E E+D ++ D +EH E + + + E P
Sbjct: 3408 PEEGPSEDDEAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGP- 3466
Query: 1700 VSNVDLASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAV-----------TGGFPSSDM 1748
++ Q + + + S +E ++ H G V G P +
Sbjct: 3467 -ADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQ 3525
Query: 1749 SE-------MDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEK-QTNPSRSTGDALDFRK 1800
+ D N ++ + ++ + H ++ SF ++ Q + RS GD +
Sbjct: 3526 GKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVH 3585
Query: 1801 EKINV--SGDLPEDNIEHHGEMDDNNADEYGYVSEFEKG-TTQALGPATLEQVDRNIDVD 1857
+++ + E + +AD + ++ + Q A+ EQ D
Sbjct: 3586 KRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSG 3645
Query: 1858 KVDTESRAGEDANLQLEKQNSEIDSVSNSSLLPKNEKR--------DQANMPVM----EK 1905
K D E ED + E+Q E + L P+ K D+ + + E+
Sbjct: 3646 K-DQEEEEIEDTLMDTEEQE-EFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEE 3703
Query: 1906 SQDDGSVKP-LGSANIDPESHLEDLISISRSYLGENTHKLSQLSVND--EELGKYHE--- 1959
QD + K + N PE E I + +L + + VN+ +EL + E
Sbjct: 3704 DQDPRTDKAHKETENEKPERSRESTIHTAHQFLMDTIFQPFLKDVNELRQELERQLEMWQ 3763
Query: 1960 PCDAPDHVKDNATA-LWRRYELSTTKLSQELTEQLRLVLEPTVASKLQGYYKTGKRIHMK 2018
P ++ + ++ A +W+ Y + T LSQ L E+LRL+LEPT A+KL+G Y+TGKR++++
Sbjct: 3764 PRESGNPEEEKVAAEMWQSYLILTAPLSQRLCEELRLILEPTQAAKLKGDYRTGKRLNIR 3823
Query: 2019 KVIQFIASYYRMDKIWLRRTRPNKRDYQVVIAVDDSHSMSESCCGDVAVEALVTVCRAVS 2078
KVI +IAS +R DKIWLRRT+P+KR YQ+ +A+DDS SM ++ +A E+L + A++
Sbjct: 3824 KVIPYIASQFRKDKIWLRRTKPSKRQYQICLAIDDSSSMVDNHTKQLAFESLAVIGNALT 3883
Query: 2079 QLEMGSLAVASFGTKGNINLLHDFDSPFTAESGVKVSRIYTSLVFFFIDISTVHLLNMLK 2138
LE+G +AV SFG ++ LLH F F+ SG ++ R+
Sbjct: 3884 LLEVGQIAVCSFGE--SVKLLHPFHEQFSDYSGSQILRL--------------------- 3920
Query: 2139 GSDCSFLTEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLDAAVVKARLPSGHNPLQQLV 2198
F+Q+ T + L+ + N AA ++ S QL+
Sbjct: 3921 ---------------CKFQQKKT----KIAQFLESVANMFAAAQQLSQNISSETA--QLL 3959
Query: 2199 LIIADGR---FHEKDNLKRCVREALASNRMVAFLLLDN--SQESIMDLMEASFEG-GKM- 2251
L+++DGR K+ + V+ A +N V F++LDN S++SI+D+ F+G G+M
Sbjct: 3960 LVVSDGRGLFLEGKERVLAAVQAARNANIFVIFVVLDNPSSRDSILDIKVPIFKGPGEMP 4019
Query: 2252 KFSKYMDSFPFPYYIVLRNIEALPRTLANLLRQ 2284
+ YM+ FPFPYYI+LR++ ALP TL++ LRQ
Sbjct: 4020 EIRSYMEEFPFPYYIILRDVNALPETLSDALRQ 4052
Score = 171 bits (432), Expect = 3e-40
Identities = 180/813 (22%), Positives = 322/813 (39%), Gaps = 112/813 (13%)
Query: 127 GCAWAHIGALRIHLLLSYNEVDPVMKYYCKYTQLEETISSLELEIQVRKECGYLSGQFLT 186
G W +G L+I L DP +K K +E + L+ E + R LS Q T
Sbjct: 1690 GSLWVSLGLLQIQTWLPQARFDPAVKREYKLNYAKEELHQLQCEWKTRN----LSSQLQT 1745
Query: 187 ----------------VEADKRKAERLEKLQAELRKLQRKIVFRSESWKYKKLMNECDEF 230
V +++ +RL+ L L K Q FR + Y+ L+ E +
Sbjct: 1746 GRDLEDEVVVSYSHPHVRLLRQRMDRLDNLTCHLLKKQ---AFRPQLPAYESLVQEIHHY 1802
Query: 231 LKHIASLEVLV-------------GNVEAEDLQQVIDRTHSWQETAMCFINRLTDEYTAY 277
+ IA + G A+ Q ++ SWQ++ F RL++EYT Y
Sbjct: 1803 VTSIAKAPAVQDLLTRLLQALHMDGPRSAQVAQSLLKEEASWQQSHHQFRKRLSEEYTFY 1862
Query: 278 NDIIQPIQVAVYEMKFGLSLVLSSFLEKEYLRKVGHENINLVTDMIYILMRFPRAASW-- 335
D + P+Q ++ +++ G+ LV S + VG + + + L+ FP
Sbjct: 1863 PDAVSPLQASILQLQHGMRLVASELHTSLHSSMVGADRLGTLATA---LLAFPSVGPTFP 1919
Query: 336 KFISVEDVGVDLHSSYKLDFGTDFYLNMGLIERLITLSSGVSADKK-VSAMRCRASIYWN 394
+ + D + S L GL + ++ S G + K A R + N
Sbjct: 1920 TYYAHADTLCSVKSEEVL---------RGLGKLILKRSGGKELEGKGQKACPTREQLLMN 1970
Query: 395 ILVQIAYSIANAKIIDRESYMLLHKIFDEFASLWMSMKVYAKSKSDHDAQQFKFKPRAFQ 454
L+ + + +D+ + L + E S W + A+ K++ ++ ++++ R +
Sbjct: 1971 ALLYLRSHVLCKGELDQRALQLFRHVCQEIISEWDEQERIAQEKAEQESSLYRYRSRNSR 2030
Query: 455 IESIMELEIPALANSSATEAFSDWKEFSYEEKSADNMESSEECEILDEEWKH---LEESI 511
E E D+ + + + +N +S+ E +E + L ++
Sbjct: 2031 TALSEEEEEEREFRKQFPLHEKDFADILVQPELEENKGTSDGQE--EEAGTNPALLSQNS 2088
Query: 512 LDNVVLIHSQLF--GSGDLVQAPGIFEISDEDRLHSFSESYKLGINLIKGAHSSNLASLD 569
+ V+LIH QL + L + + L F Y+ G +L+ + L+
Sbjct: 2089 MQAVMLIHQQLCLNFARSLWYQQTLPPHEAKHYLSLFLSCYQTGASLVTHFYPLMGVELN 2148
Query: 570 AKLIPEHLFYLSIDYRRKFHSSS-----KSANRYNFYKDSNAHEIEQMLKVLAPLRQQIT 624
+L+ L ++ + F + K Y+FY+ N E Q VL + ++
Sbjct: 2149 DRLLGSQLLACTLSHNTLFGEAPSDLMVKPDGPYDFYQHPNVPEARQCQPVLQGFSEAVS 2208
Query: 625 SLLNEWEEQNDLQRFLDVIDMLLTLPSDIPLAKAFSGLQFLLHKAQVMQENHSK-FTFSN 683
LL +W E L++ L V+D + + P P++K +GL+ LL KAQ +EN S+ +
Sbjct: 2209 HLLQDWPEHPALEQLLVVMDRIRSFPLSSPISKFLNGLEILLAKAQDWEENASRVLSLRK 2268
Query: 684 QLKSVFDLMSSWHKMELGSWPVLLDEVMDQYENNAKKSVLSSSIHYF*SINFPKSNFYFS 743
L + ++ W K+EL W + LD M ++ + K H+F + +
Sbjct: 2269 HLDLISQMIIRWRKLELNCWSMSLDNTMKRHTEKSTK-------HWFSIYQMLEKHMQEQ 2321
Query: 744 YES-------------CSLEDFIQTSSFGEFRKRLQLLYAFLGQNHTSACLKINSSNIVF 790
E +L+ FI+ SS GEF RLQ+L F
Sbjct: 2322 TEEQEDDKQMTLMLLVSTLQAFIEGSSLGEFHVRLQMLLVF------------------- 2362
Query: 791 FLHCWTLQLLSDGAVNILVQYVWILCAVLTNHIDASRKEIL-------TELKDLVKLCRW 843
HC L + + L +W L D + +I+ ELK+ VK+ +W
Sbjct: 2363 --HCHVLLMPQVEGKDSLCSVLWNLYHYYKQFFDRVQAKIVELRSPLEKELKEFVKISKW 2420
Query: 844 EQDKSYSSIENLKKSRQKLKKLIKKHTDILQEP 876
+S ++++K+ + L K +KK +L EP
Sbjct: 2421 NDVSFWSIKQSVEKTHRTLFKFMKKFEAVLSEP 2453
Score = 60.1 bits (144), Expect = 8e-07
Identities = 70/328 (21%), Positives = 125/328 (37%), Gaps = 35/328 (10%)
Query: 1520 EDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQSGDDSCDEGDAQNDEAAAQNEF 1579
E E D ++ E+ V+D +E DS SD G+D+ E D E
Sbjct: 3151 EGEGMKDVSDQIENEEQVEDTFQKGQEKDKDPDSKSDIKGEDNAIEMSEDFDGKMHDGEL 3210
Query: 1580 ---DDEENGDDVNMDKEAAHSDATGLKPD--------EPDHSSDMEIDLNANEDVDP-IE 1627
+D+E D D + D G + D + D D E + N E+ P ++
Sbjct: 3211 EEQEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMD 3270
Query: 1628 EGDQE--GHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSE-KDDLGQEHQEND-DMNSM 1683
E D E DD+ ++GN + D+ E+ E D + +D + ++ E + D N +
Sbjct: 3271 EEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDEREYDENEV 3330
Query: 1684 DPKNDTSESSDVVNPQVSNVDLASQSKSDLQ-TSGSENIASQSNLSNSHHDFGNPAVTGG 1742
DP + E P+ +DL D + +G E+ ++ + + G
Sbjct: 3331 DPYHGNQEKV----PEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAG 3386
Query: 1743 FPSSDMSEMDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEK-QTNPSRSTGDALDFRKE 1801
+ + E + + ++S S +P+ + + + +E+ T GDA +E
Sbjct: 3387 HEAEERGETETDQNESQ-----SPQEPEEGPSEDDEAEGEEEMDTGADDQDGDAAQHPEE 3441
Query: 1802 KINVSGDLPEDNIEHHGEMDDNNADEYG 1829
+ + E D ADE G
Sbjct: 3442 H--------SEEQQQSVEEKDKEADEEG 3461
>UniRef100_Q6AI22 Hypothetical protein DKFZp686H16106 [Homo sapiens]
Length = 2810
Score = 268 bits (686), Expect = 1e-69
Identities = 250/931 (26%), Positives = 412/931 (43%), Gaps = 152/931 (16%)
Query: 1450 KEEQEESKEVPGNDNTGIEMDQDFQADAVS--LSEDSSENEDCDGENEELESEMGP-TGP 1506
KE+ + ++ G DN IEM +DF L E ++E D E +L+ MG G
Sbjct: 1925 KEDPDSKSDIKGEDNA-IEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGE 1983
Query: 1507 DSEAVGEKIW---DQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQSGDDSC 1563
+++ + E++W D+ EDE +D + E+GP + + D EL AKDD+ SG+ +
Sbjct: 1984 EADKLDERLWGDDDEEEDEEEEDNKTE-ETGPGMDEEDS---ELVAKDDNLD--SGNSNK 2037
Query: 1564 DEGDAQNDEAAAQNEFDDEENGDD-VNMDKEAAHSDATGLKP--------------DEPD 1608
D+ E + E DD G+D +N + D + P D PD
Sbjct: 2038 DKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPD 2097
Query: 1609 HSSDMEIDLNANEDVDPIEEGDQE------------GH----------DDSAENGNQEDE 1646
+ D N ED D EEG++E GH D + QE E
Sbjct: 2098 DLNLDSEDKNGGEDTDN-EEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPE 2156
Query: 1647 TCPPDEIMEEAHTEVDVSSEKDDLG-----QEHQENDDMNSMDPKNDTSESSDVVNPQVS 1701
P ++ E E+D ++ D +EH E + + + E P +
Sbjct: 2157 EGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGP--A 2214
Query: 1702 NVDLASQSKSDLQTSGSENIASQSNLSNSHHDFGNPAV-----------TGGFPSSDMSE 1750
+ Q + + + S +E ++ H G V G P + +
Sbjct: 2215 DQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGK 2274
Query: 1751 -------MDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEK-QTNPSRSTGDALDFRKEK 1802
D N ++ + ++ + H ++ SF ++ Q + RS GD + ++
Sbjct: 2275 EEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKR 2334
Query: 1803 INV--SGDLPEDNIEHHGEMDDNNADEYGYVSEFEKG-TTQALGPATLEQVDRNIDVDKV 1859
+ + E + +AD + ++ + Q A+ EQ D K
Sbjct: 2335 LRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGK- 2393
Query: 1860 DTESRAGEDANLQLEKQNSEIDSVSNSSLLPKNEKR--------DQANMPVM----EKSQ 1907
D E ED + E+Q E + L P+ K D+ + + E+ Q
Sbjct: 2394 DQEEEEIEDTLMDTEEQE-EFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQ 2452
Query: 1908 DDGSVKP-LGSANIDPESHLEDLISISRSYLGENTHKLSQLSVND--EELGKYHE---PC 1961
D + K + N PE E I + +L + + VN+ +EL + E P
Sbjct: 2453 DPRTDKAHKETENEKPERSRESTIHTAHQFLMDTIFQPFLKDVNELRQELERQLEMWQPR 2512
Query: 1962 DAPDHVKDNATA-LWRRYELSTTKLSQELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKV 2020
++ + ++ A +W+ Y + T LSQ L E+LRL+L PT A+KL+G Y+TGKR++++KV
Sbjct: 2513 ESGNPEEEKVAAEMWQSYLILTAPLSQRLCEELRLILVPTQAAKLKGDYRTGKRLNIRKV 2572
Query: 2021 IQFIASYYRMDKIWLRRTRPNKRDYQVVIAVDDSHSMSESCCGDVAVEALVTVCRAVSQL 2080
I +IAS +R DKIWLRRT+P+KR YQ+ +A+DDS SM ++ +A E+L + A++ L
Sbjct: 2573 IPYIASQFRKDKIWLRRTKPSKRQYQICLAIDDSSSMVDNHTKQLAFESLAVIGNALTLL 2632
Query: 2081 EMGSLAVASFGTKGNINLLHDFDSPFTAESGVKVSRIYTSLVFFFIDISTVHLLNMLKGS 2140
E+G +AV SFG ++ LLH F F+ SG ++ R+
Sbjct: 2633 EVGQIAVCSFGE--SVKLLHPFHEQFSDYSGSQILRL----------------------- 2667
Query: 2141 DCSFLTEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLDAAVVKARLPSGHNPLQQLVLI 2200
F+Q+ T + L+ + N AA ++ S QL+L+
Sbjct: 2668 -------------CKFQQKKT----KIAQFLESVANMFAAAQQLSQNISSETA--QLLLV 2708
Query: 2201 IADGR---FHEKDNLKRCVREALASNRMVAFLLLDN--SQESIMDLMEASFEG-GKM-KF 2253
++DGR K+ + V+ A +N V F++LDN S++SI+D+ F+G G+M +
Sbjct: 2709 VSDGRGLFLEGKERVLAAVQAARNANIFVIFVVLDNPSSRDSILDIKVPIFKGPGEMPEI 2768
Query: 2254 SKYMDSFPFPYYIVLRNIEALPRTLANLLRQ 2284
YM+ FPFPYYI+LR++ ALP TL++ LRQ
Sbjct: 2769 RSYMEEFPFPYYIILRDVNALPETLSDALRQ 2799
Score = 170 bits (431), Expect = 4e-40
Identities = 187/853 (21%), Positives = 335/853 (38%), Gaps = 120/853 (14%)
Query: 127 GCAWAHIGALRIHLLLSYNEVDPVMKYYCKYTQLEETISSLELEIQVRKECGYLSGQFLT 186
G W +G L+I L DP +K K ++E + L+ E + R LS Q T
Sbjct: 435 GSLWVSLGLLQIQTWLPQARFDPAVKREYKLNYVKEELHQLQCEWKTRN----LSSQLQT 490
Query: 187 ----------------VEADKRKAERLEKLQAELRKLQRKIVFRSESWKYKKLMNECDEF 230
V +++ +RL+ L L K Q FR + Y+ L+ E +
Sbjct: 491 GRDLEDEVVVSYSHPHVRLLRQRMDRLDNLTCHLLKKQ---AFRPQLPAYESLVQEIHHY 547
Query: 231 LKHIASLEVLV-------------GNVEAEDLQQVIDRTHSWQETAMCFINRLTDEYTAY 277
+ IA + G A+ Q ++ SWQ++ F RL++EYT Y
Sbjct: 548 VTSIAKAPAVQDLLTRLLQALHIDGPRSAQVAQSLLKEEASWQQSHHQFRKRLSEEYTFY 607
Query: 278 NDIIQPIQVAVYEMKFGLSLVLSSFLEKEYLRKVGHENINLVTDMIYILMRFPRAASW-- 335
D + P+Q ++ +++ G+ LV S + VG + + + L+ FP
Sbjct: 608 PDAVSPLQASILQLQHGMRLVASELHTSLHSSMVGADRLGTLATA---LLAFPSVGPTFP 664
Query: 336 KFISVEDVGVDLHSSYKLDFGTDFYLNMGLIERLITLSSGVSADKK-VSAMRCRASIYWN 394
+ + D + S L GL + ++ S G + K A R + N
Sbjct: 665 TYYAHADTLCSVKSEEVL---------RGLGKLILKRSGGKELEGKGQKACPTREQLLMN 715
Query: 395 ILVQIAYSIANAKIIDRESYMLLHKIFDEFASLWMSMKVYAKSKSDHDAQQFKFKPRAFQ 454
L+ + + +D+ + L + E S W + A+ K++ ++ ++++ R +
Sbjct: 716 ALLYLRSHVLCKGELDQRALQLFRHVCQEIISEWDEQERIAQEKAEQESGLYRYRSRNSR 775
Query: 455 IESIMELEIPALANSSATEAFSDWKEFSYEEKSADNMESSEECEILDEEWKH---LEESI 511
E E D+ + + +N +S+ E +E + L ++
Sbjct: 776 TALSEEEEEEREFRKQFPLHEKDFADILVQPTLEENKGTSDGQE--EEAGTNPALLSQNS 833
Query: 512 LDNVVLIHSQLF--GSGDLVQAPGIFEISDEDRLHSFSESYKLGINLIKGAHSSNLASLD 569
+ V+LIH QL + L + + L F Y+ G +L+ + L+
Sbjct: 834 MQAVMLIHQQLCLNFARSLWYQQTLPPHEAKHYLSLFLSCYQTGASLVTHFYPLMGVELN 893
Query: 570 AKLIPEHLFYLSIDYRRKFHSSS-----KSANRYNFYKDSNAHEIEQMLKVLAPLRQQIT 624
+L+ L ++ + F + K Y+FY+ N E Q VL + ++
Sbjct: 894 DRLLGSQLLACTLSHNTLFGEAPSDLMVKPDGPYDFYQHPNVPEARQCQPVLQGFSEAVS 953
Query: 625 SLLNEWEEQNDLQRFLDVIDMLLTLPSDIPLAKAFSGLQFLLHKAQVMQENHSK-FTFSN 683
LL +W E L++ L V+D + + P P++K +GL+ LL KAQ +EN S+ +
Sbjct: 954 HLLQDWPEHPALEQLLVVMDRIRSFPLSSPISKFLNGLEILLAKAQDWEENASRALSLRK 1013
Query: 684 QLKSVFDLMSSWHKMELGSWPVLLDEVMDQYENNAKKSVLSSSIHYF*SINFPKSNFYFS 743
L + ++ W K+EL W + LD M ++ + K H+F + +
Sbjct: 1014 HLDLISQMIIRWRKLELNCWSMSLDNTMKRHTEKSTK-------HWFSIYQMLEKHMQEQ 1066
Query: 744 YES-------------CSLEDFIQTSSFGEFRKRLQLLYAFLGQNHTSACLKINSSNIVF 790
E +L+ FI+ SS GEF RLQ+L F
Sbjct: 1067 TEEQEDDKQMTLMLLVSTLQAFIEGSSLGEFHVRLQMLLVF------------------- 1107
Query: 791 FLHCWTLQLLSDGAVNILVQYVWILCAVLTNHIDASRKEIL-------TELKDLVKLCRW 843
HC L + + L +W L D + +I+ ELK+ VK+ +W
Sbjct: 1108 --HCHVLLMPQVEGKDSLCSVLWNLYHYYKQFFDRVQAKIVELRSPLEKELKEFVKISKW 1165
Query: 844 EQDKSYSSIENLKKSRQKLKKLIKKHTDILQEPMDKLI--------RDVLHKGSISGVSD 895
+S ++++K+ + L K +KK +L EP + D L + + S+
Sbjct: 1166 NDVSFWSIKQSVEKTHRTLFKFMKKFEAVLSEPCRSSLVESDKEEQPDFLPRPTDGAASE 1225
Query: 896 LPLFSDENRLYQE 908
L + NR +E
Sbjct: 1226 LSSIQNLNRALRE 1238
Score = 56.2 bits (134), Expect = 1e-05
Identities = 74/335 (22%), Positives = 130/335 (38%), Gaps = 47/335 (14%)
Query: 1520 EDETPDDTGEKYESGPSVKDGDGSNKELRAKD-DSTSDQSGDDSCDE---------GDAQ 1569
E E D ++ + V+D +E +D DS SD G+D+ E D +
Sbjct: 1896 EGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGE 1955
Query: 1570 NDEAAAQNEFDDEENGDDVNMDKEAAHSDATGLKPD--------EPDHSSDMEIDLNANE 1621
+E +E D E GD +DK D G + D + D D E + N E
Sbjct: 1956 LEEQEEDDEKSDSEGGD---LDKHM--GDLNGEEADKLDERLWGDDDEEEDEEEEDNKTE 2010
Query: 1622 DVDP-IEEGDQE--GHDDSAENGNQEDETCPPDEIMEEAHTEVDVSSE-KDDLGQEHQEN 1677
+ P ++E D E DD+ ++GN + D+ E+ E D + +D + ++ E
Sbjct: 2011 ETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDER 2070
Query: 1678 D-DMNSMDPKNDTSESSDVVNPQVSNVDLASQSKSDLQ-TSGSENIASQSNLSNSHHDFG 1735
D D N +DP + E P+ +DL D + +G E+ ++ + +
Sbjct: 2071 DYDENEVDPYHGNQEKV----PEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIK 2126
Query: 1736 NPAVTGGFPSSDMSEMDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEK-QTNPSRSTGD 1794
G + + E + + ++S S +P+ + + + +E+ T GD
Sbjct: 2127 EKPEEAGHEAEERGETETDQNESQ-----SPQEPEEGPSEDDKAEGEEEMDTGADDQDGD 2181
Query: 1795 ALDFRKEKINVSGDLPEDNIEHHGEMDDNNADEYG 1829
A +E + + E D ADE G
Sbjct: 2182 AAQHPEEH--------SEEQQQSVEEKDKEADEEG 2208
>UniRef100_Q9V628 CG13185-PA [Drosophila melanogaster]
Length = 5303
Score = 258 bits (660), Expect = 1e-66
Identities = 243/945 (25%), Positives = 409/945 (42%), Gaps = 176/945 (18%)
Query: 1448 QKKEEQEESKEVPGNDNTGIEMDQDFQADAVSLSEDSSENEDCDGENEELESEMGPTGPD 1507
+ ++++ + +E + GIEM DF A + + ++ E E+L EMG T
Sbjct: 4419 EDRKDEGDKQEPDCKEEKGIEMSDDFDAKMQDVEKPEEDDSGESEEEEDLNKEMGETEEG 4478
Query: 1508 SEAVGEKIWDQNEDETPDDTGE----KYESGPSVKDGDGSNKELRAKDDSTSDQSGDDSC 1563
+E + ++IW +E+E P++ E + + G KD ++ +L K+D+ + D+
Sbjct: 4479 AEKLDDQIWGDDEEEKPEEEQEPDMNEEDQGKGSKDEKDAHNDLDTKNDAAKEDGKDEHE 4538
Query: 1564 DEG-DAQNDEAAAQNEFDDEENGDDV---NMDKEAAHSDATGL-KPDEPDH--------- 1609
+G DA N+ + + ++ DD+ MD+E ++ L +P EP+
Sbjct: 4539 KDGLDATNEPSGEDKRKEQAKDIDDMKDPEMDEEQTNAMHNELEEPPEPEEMDLGDMNNV 4598
Query: 1610 -----------SSDMEIDLNA-NEDVDPIEEGDQEGHDDSAENGNQEDETCPPDEIMEEA 1657
+ + D++A E++ P EE + +G D+ N + ++ D +EA
Sbjct: 4599 DEGHDDQDEQPTDENPFDIDAMKENMQPAEEPEADGDDEHDANEEGDPQSDGSDSEEDEA 4658
Query: 1658 HTEVDVSSEKDDLGQEHQENDDMNSMD-PKNDTSESSDVVNPQVSNVDLASQ-------- 1708
TE + E G+E D+ + + K E D P+ S D +
Sbjct: 4659 GTEAKPAEEDHGEGEEATPEDEKDEAETQKRGELEDEDDSKPEDSPEDSKEEKEEKREEK 4718
Query: 1709 ----SKSDLQTSGSENIAS--QSNLSNSHHDFGNPAVTGGFPSSDMSEMDI--------- 1753
S+S + S EN+ S +++ S+S P + E +
Sbjct: 4719 PEEHSQSKDKASKEENVQSMPETDQSSSADQVQQPQDPDIKQDQKLDEQETGEEKDGVGQ 4778
Query: 1754 --NMSDSSNTGGFSKTQPK-SHLPQHEHSFSQEK----QTNPSRSTGDALDFRKEKINVS 1806
N +D G ++TQ S + +QEK +TN RS G+A + +++
Sbjct: 4779 AENDADDGGHQGVAETQETVSQEDRKNERQTQEKRKQGRTNEERSLGEAEQNKLKQLKTI 4838
Query: 1807 GDLPEDNIEHHGE------MDDNNADEYGYVSEFEKGTTQALGPATLEQV---------- 1850
L + E MD A+EY +V E + L AT EQ
Sbjct: 4839 DQLKDSKESDDAEQEKPEPMDQTEAEEYQHVKEPKNSDKTTLDNATEEQSKKIQHQEDEP 4898
Query: 1851 --DRNIDVDKVDTESRAGEDA-----NLQLEKQNSEIDSVSNSSLLPKNEKRDQANMPVM 1903
+ I+ + VD A E A + +LE+ +E S P ++ + +
Sbjct: 4899 PNEEEIEAENVDELMEAEEPAVDPEDDAELEQLGAE--KTEQKSDKPSKTEKSKEQLETP 4956
Query: 1904 EKSQDDGSV-----KPLGSAN---------IDPESHLEDLISISRSYLGENTHK-LSQLS 1948
E + +G V P S +D SH EDL S + L + K L+
Sbjct: 4957 EGMEIEGEVVLTMTVPRSSETTAHSNSEILLDKSSHAEDLSSAEQIELRQQYQKQLTTFR 5016
Query: 1949 VNDEELGKYHEPCDAPDHVKDNATALWRRYELSTTKLSQELTEQLRLVLEPTVASKLQGY 2008
V E HE + W+ T+ ++EL EQLRL+LEPT ++L+G
Sbjct: 5017 VAQPE----HEDYET-----------WQGISNRMTQNARELCEQLRLILEPTKCTRLKGD 5061
Query: 2009 YKTGKRIHMKKVIQFIASYYRMDKIWLRRTRPNKRDYQVVIAVDDSHSMSESCCGDVAVE 2068
Y+TG+RI+MKK+I +IAS +R DKIWLRRT+P +RDY++ IA+DDS SM + + +E
Sbjct: 5062 YRTGRRINMKKIIPYIASQFRKDKIWLRRTKPAQRDYKITIAIDDSKSMHHNNSKTLTLE 5121
Query: 2069 ALVTVCRAVSQLEMGSLAVASFGTKGNINLLH--DFDSPFTAESGVKVSRIYTSLVFFFI 2126
A+ V +A++ LE G L++ SFG I L H FD P
Sbjct: 5122 AISLVSQALTLLESGRLSIVSFGEAPQIILNHTEQFDGP--------------------- 5160
Query: 2127 DISTVHLLNMLKGSDCSFLTEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLDAAVVKAR 2186
++V+ L F Q+ T + LL F+ A +
Sbjct: 5161 ----------------------RLVNALNFAQDKT----KIAGLLNFIR----TANAEES 5190
Query: 2187 LPSGHNPL-QQLVLIIADGR--FHE-KDNLKRCVREALASNRMVAFLLLDN--SQESIMD 2240
G N L + L+LI++DGR F E N+K ++ A + ++++DN ++ SI+D
Sbjct: 5191 GTGGDNGLFENLLLILSDGRNIFSEGAQNVKNAIKLARLQRIFLVYIIIDNPDNKNSILD 5250
Query: 2241 LMEASFEG-GKMKFSKYMDSFPFPYYIVLRNIEALPRTLANLLRQ 2284
+ + G + + Y+DSFPFPYY+++R++ LP L+ +RQ
Sbjct: 5251 IQHVAVNADGSVNINSYLDSFPFPYYVIVRDLNQLPLVLSEAMRQ 5295
Score = 95.5 bits (236), Expect = 2e-17
Identities = 171/856 (19%), Positives = 335/856 (38%), Gaps = 168/856 (19%)
Query: 115 STTTDFNFNYTIGCAWAHIGALRIHLLLSYNEVDPVMKYYCKYTQLEETISSLELE---- 170
S T DF + T A +GA+ + LL + +DPV K K + E I L
Sbjct: 3070 SMTKDFEVSLTN----ALVGAIELCLLTNTPLIDPVEKNRLKNEYIAEDIDCLSTLTTAY 3125
Query: 171 --IQVRKECGYLSGQFLTVEADKRKAERLEKLQAELRKLQRKIVFRSESWKYKKLMNECD 228
+++ + + G+ + E + R L++ Q +L +K+ RSE Y L+ +
Sbjct: 3126 DFMKIAMKYRHF-GEEIYSELELRLRTALQRQQ----QLSQKLALRSEKCLYASLVQDIT 3180
Query: 229 EFLKHIASLEVLVG-----NVEAEDLQ--------------QVIDRTHSWQETAMCFINR 269
FL E L + E E+ Q +V+ + W A F++
Sbjct: 3181 HFLHSNGDCESLYKLFQLIHSEWENFQGLHVATSAQLKSSIEVLGKLDLWLANAQRFVHH 3240
Query: 270 LTDEYTAY-NDIIQPIQVAVYEMKFGLSLVLSSFLEKEYLRKVGHENINLVTDMIYILMR 328
Y+AY D ++PI+ +V ++ + G E++ ++
Sbjct: 3241 TLSRYSAYYQDFVEPIKCSVNQL------------------RFGLESLKVI--------- 3273
Query: 329 FPRAASWKFISVEDVGVDLHSSYKLDFGTDFYLNMGLIERLITLSSGVSADKKVSAMRCR 388
F V+ G ++ E++ + + R
Sbjct: 3274 --------FTRVQQAG-----------------SVSQAEQMQQTIGDIVQFPSQHPLVIR 3308
Query: 389 ASIYWNILVQIAYS------IANAKIIDRESYMLLHKIFDE--FASLWMSMKVYAKSKSD 440
S + +L ++ +S + AK+ + +Y+ L ++ DE FA+ ++ + ++
Sbjct: 3309 NSRLYGLLAELPHSEYEYFRLLKAKLSELSNYIALGRVIDETTFAAYDDALSICNQTWQQ 3368
Query: 441 HDAQQFKFKPRAFQ---------IESIMELEIPALANSSATEAFSDWKEFSYE------- 484
+ ++ + K A ++S +E+ + ++ T D+ EF +
Sbjct: 3369 EEHRRCQLKAEAESLYVTKTKGGVDSEELIEMQEIEHNFPTNLDEDFAEFVSQPTLEQVL 3428
Query: 485 --EKSADNMESSEECEILDEEWKHLEESILDNVVLIHSQLFGSGDLVQAPGIFEISDEDR 542
+K A + + +++E++ L + +D V+ H+Q++ + P + +
Sbjct: 3429 KLDKKASAKDKQSQI-VVEEDYAFLARNFID-VMTRHTQVYYK----EQPKSSKELELHL 3482
Query: 543 LHSFSESYKLGINLIKGAHSSNLASLDAKLIPEHLFYLSIDYRRKFH---SSSKSANRYN 599
L + +++ NL ++ +SL+ + F L++ ++ S++ Y+
Sbjct: 3483 LAPYQARFQVFANLHGHYKTALGSSLEERACNGLAFGLALQQKQLRDIELEEGVSSSPYD 3542
Query: 600 FYKDSNAHEIEQMLKVLAPLRQQITSLLNEWEEQNDLQRFLDVIDMLLTLPSDIPLAKAF 659
FYKDSN EI+ L V+ + +++ L ++ E L VI + LP+ P+ +
Sbjct: 3543 FYKDSNISEIQSCLDVMERIEKRVLEQLEQYPEHAGLADIKLVISRIRRLPAHAPVVRFN 3602
Query: 660 SGLQFLLHKAQVMQE-NHSKFTFSNQLKSVFDLMSSWHKMELGSWPVLLDEVMDQYENNA 718
+G Q L K + E H ++ V + + W ++EL W L + Q E A
Sbjct: 3603 TGFQLLRQKLALWNEVAHRNNNLVSEEIEVAEFVQRWTRLELQHWRNCLGQTAAQVELQA 3662
Query: 719 KK------SVLSSSIHY------F*SINFPKSNFYFSY--------ESCSLE-------- 750
+ ++L IH + I + F + ES LE
Sbjct: 3663 YRYWFFIYNLLQQFIHQKQLDHSYTDIKLAEQRFAQDHLLDAQDLGESQRLELAQVVRIL 3722
Query: 751 -DFIQTSSFGEFRKRLQLLYAF-LGQNHTSACLKINS-SNIVFFLHCWTLQLLSDGAVNI 807
F++ S +G+F RLQLL F L ++ KIN ++ LH LQL
Sbjct: 3723 RQFVEASCYGDFHIRLQLLQGFELYLHNVERAGKINGLPPLIAALH--NLQL-------- 3772
Query: 808 LVQYVWILCAVLTNHIDASRKEILTELKDLVKLCRWEQDKSYSSIENLKKS-RQKLKKLI 866
Y + + R I +LK+ VK+ + +D SY S+ N S + L K +
Sbjct: 3773 ---YFSQFAGEIADSAKLRRSPIEKKLKEFVKIQSYSKDLSYFSMRNSVASVHRNLNKFL 3829
Query: 867 KKHTDILQEPMDKLIR 882
K++ +QE + ++ +
Sbjct: 3830 KEYRLSIQEKISEVFQ 3845
Score = 63.5 bits (153), Expect = 7e-08
Identities = 100/504 (19%), Positives = 186/504 (36%), Gaps = 62/504 (12%)
Query: 1476 DAVSLSEDSSENEDCDGENEELESEMGPTGPDSEAVGE-KIWDQNEDETPDDTGEKYESG 1534
D + E S+ E +GE LE G + E ++ D E D G+K E
Sbjct: 4372 DLMQDEEGQSKQESKNGEGFGLEDGTGENDASDKIESEDQLDDAKRPEDRKDEGDKQE-- 4429
Query: 1535 PSVKDGDGSNKELRAKDDSTSDQSGDDSCDEGDAQNDEAAAQNEFDDEENGDDVNMDKEA 1594
P K+ + G + D+ DA+ + E D E+ ++ +++KE
Sbjct: 4430 PDCKE-----------------EKGIEMSDDFDAKMQDVEKPEEDDSGESEEEEDLNKEM 4472
Query: 1595 AHSDATGLKPDEPDHSSDMEIDLNANEDVDPIEEGDQEGHDDSAENGNQED---ETCPPD 1651
++ K D+ D E ++ D EE +G D + N D + D
Sbjct: 4473 GETEEGAEKLDDQIWGDDEEEKPEEEQEPDMNEEDQGKGSKDEKDAHNDLDTKNDAAKED 4532
Query: 1652 EIMEEAHTEVDVSSEKDDLGQEHQENDDMNSM-DPKNDTSESSDVVN-----PQVSNVDL 1705
E +D ++E + ++ D++ M DP+ D +++ + N P+ +DL
Sbjct: 4533 GKDEHEKDGLDATNEPSGEDKRKEQAKDIDDMKDPEMDEEQTNAMHNELEEPPEPEEMDL 4592
Query: 1706 ASQSKSDLQTSGSENIASQSN------LSNSHHDFGNPAVTG---------GFPSSDMSE 1750
+ D + + N + + P G G P SD S+
Sbjct: 4593 GDMNNVDEGHDDQDEQPTDENPFDIDAMKENMQPAEEPEADGDDEHDANEEGDPQSDGSD 4652
Query: 1751 MDINMSDSSNTGGFSKTQPKSHLPQHEHSFSQEKQTNPSRSTGDALDFRKEKINVSGDLP 1810
S+ G +K + H E + EK ++ G+ D E + D P
Sbjct: 4653 -----SEEDEAGTEAKPAEEDHGEGEEATPEDEKDEAETQKRGELED---EDDSKPEDSP 4704
Query: 1811 EDNIEHHGEMDDNNADEYGYVSEFEKGTTQALGPATLEQVDRNIDVDKVD--TESRAGED 1868
ED+ E E + +E+ S+ + ++ ++ + D++ D+V + +D
Sbjct: 4705 EDSKEEKEEKREEKPEEH---SQSKDKASKEENVQSMPETDQSSSADQVQQPQDPDIKQD 4761
Query: 1869 ANLQLEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKSQDDGSVKPLGSANIDPESHLED 1928
L ++ E D V + +N+ D + V E +Q+ S + + E +
Sbjct: 4762 QKLDEQETGEEKDGVGQA----ENDADDGGHQGVAE-TQETVSQEDRKNERQTQEKRKQG 4816
Query: 1929 LISISRSYLGENTHKLSQLSVNDE 1952
+ RS +KL QL D+
Sbjct: 4817 RTNEERSLGEAEQNKLKQLKTIDQ 4840
>UniRef100_UPI000021BFA6 UPI000021BFA6 UniRef100 entry
Length = 5086
Score = 243 bits (619), Expect = 7e-62
Identities = 243/946 (25%), Positives = 416/946 (43%), Gaps = 172/946 (18%)
Query: 1444 LSMMQKKEEQEESKEVPGNDNTGIEMDQD-FQADAVSLS-----EDSSENEDCDGENEEL 1497
LS + ++ Q+++ E ++ I+M D + D S+ +D + D DG+ +E+
Sbjct: 4168 LSELAQEPNQQQNNEDMDDEEDAIDMGTDEMEGDLASVGGGDDEQDGERSGDEDGDEDEM 4227
Query: 1498 ESEMGPTGP-DSEAVGEKIWDQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSD 1556
+ + G D AV EK+W+ + +E D SG KD + + AK +
Sbjct: 4228 DEQAGDVDDLDPTAVDEKMWNDDGEEADKDQRGDAASGKQQKDEEVGATDSTAKQAAEQQ 4287
Query: 1557 QS-----GDDSCDEGDAQNDEAAAQNEFDDEENGDDVNMDKEAAHSDATGLKPDEPDHSS 1611
Q +++ +E Q +EA Q E N D N+ + A + ++ D D
Sbjct: 4288 QGEEPAEAEEAGEEAGPQEEEAKPQEEL----NRQDQNVQESEALALPDEMELDRDDDDG 4343
Query: 1612 DMEIDLNANEDVDPIEEGDQ------EGHDDSAENGNQEDETCPPDE---IMEEAHTEVD 1662
D + D + D P E DQ E D+ +++D T P E I +E +E +
Sbjct: 4344 DGDDDDGDDLDDLPELENDQAEPQGMETDSDNDYGDDKDDITEAPKEAEGIEDEIASEDE 4403
Query: 1663 VSSEKDDLGQEHQENDDMNSMDPKNDT-SESSDVVNPQVSNVDL--ASQSKSDLQTSGSE 1719
+ + +D+G+ + D+ DPK++ ++ D + S D A + +D + + S
Sbjct: 4404 MGIDDEDIGRGEDQMDE----DPKDEAETDDPDAAKEKESGTDQNQARDNNADPENAASS 4459
Query: 1720 NIASQSNLSNSHHDFGNPAVT----GGFPSSDMSEMDINMSDSSNTGGFSKTQPKSHLPQ 1775
++ S + N T G D+++ + S+ + G + + ++ P
Sbjct: 4460 DVKSGGGQDQHDNQQDNSEETQENAGQRDQGDITDPGAEQNTSAASQGRASGREEAPQPD 4519
Query: 1776 HEHSF-SQEKQTNPSRSTGDALD--FRKEKI--NVSGDLPEDNIEHHGE--MDDNNADEY 1828
E S E++T P + GD L+ +R K + D E + + + D DE+
Sbjct: 4520 AEQGADSAEQETLPFKKLGDLLEKWYRNNKDIREATKDQDEADTKRQAQEPRDQAATDEF 4579
Query: 1829 GYVS-EFEKGTTQALGPATLEQVDRNIDVDKVDTESRAGEDANLQLEKQ--NSEIDSVSN 1885
++ E TQALG AT E+ D +D E+ A +D + Q + E D V
Sbjct: 4580 QHLQDETAPADTQALGAATDEEAKPIDDTMAIDEEAEADKDKPQLMPDQMEDEEDDKVMQ 4639
Query: 1886 SSL------------------LPKNEK--RDQANMPVMEK----------SQDDGSVKPL 1915
S + KN K RDQ V S + G V+
Sbjct: 4640 DSAQEDADEAAGDDNANAEDGIGKNNKNDRDQGRSGVATHQGAYHRDNTASPEPGPVEQA 4699
Query: 1916 GSANIDPESHLEDLISISRSYLGENTHKLSQLSVNDEELGKYHEPCDAPDHVKDNATAL- 1974
A D E+ ED + E + +LS + DEE + ++D A +
Sbjct: 4700 QDA-ADGETEEED------EMVQETSTQLSATHLVDEEAEQ--------STLRDLAECVE 4744
Query: 1975 -WRRYELSTTKLSQELTEQLRLVLEPTVASKLQGYYKTGKRIHMKKVIQFIASYYRMDKI 2033
W +++ T LS L QLRL+L P+ A+KL G ++TGKR+++KK+I +IAS Y+ DKI
Sbjct: 4745 SWSKFQTRTHGLSLSLASQLRLILTPSQATKLSGSHRTGKRLNIKKIIPYIASGYKRDKI 4804
Query: 2034 WLRRTRPNKRDYQVVIAVDDSHSMSESCC----------------------GDVAVEALV 2071
W+RR+ P KR YQ+++ VDDS SM + G +A+E+LV
Sbjct: 4805 WMRRSVPTKRTYQILLCVDDSLSMGNNGMTSSQAVAPGGAVASKDADVEGPGALALESLV 4864
Query: 2072 TVCRAVSQLEMGSLAVASFGTKGNINLLHDFDSPF-TAESGVKVSRIYTSLVFFFIDIST 2130
V RA++ LE+G + V FG+ ++ + H+ PF T ++G +V
Sbjct: 4865 MVSRALNMLEVGQVGVLGFGS--SVFVAHELAEPFSTLDAGARV---------------- 4906
Query: 2131 VHLLNMLKGSDCSFLTEEQMVSNLTFKQENTIADEPVVDLLKFLTNKLDAAVVKARLPSG 2190
+ N F+Q+ T V L++ + + A +++ SG
Sbjct: 4907 --------------------LQNFCFRQDGT----DVALLMRRIIDHFTTARLQSS-SSG 4941
Query: 2191 HNPLQQLVLIIADGRFHEK--DNLKRCVREALASNRMVAFLLLDN------SQESIMDLM 2242
L QL L+++DG D ++R +REA+ MV F+++D+ +S++DL
Sbjct: 4942 QQDLWQLALVMSDGLTPSSTHDRIRRLLREAMEERIMVVFIVMDDPIATGKKGDSVLDLK 5001
Query: 2243 EASFE-----GGKMKFSKYMDSFPFPYYIVLRNIEALPRTLANLLR 2283
EA F ++ +Y+D+FPFPYY+++ +++ LP LA LLR
Sbjct: 5002 EAKFVKDDAGNSRVVLERYLDTFPFPYYLIVHHLDDLPNALAGLLR 5047
Score = 65.9 bits (159), Expect = 1e-08
Identities = 74/307 (24%), Positives = 124/307 (40%), Gaps = 31/307 (10%)
Query: 591 SSKSANRYNFYKDSNAHEIEQMLKVLAPLRQQITSLLNEWEEQNDLQRFLDVIDM---LL 647
S+ N YNFY D+N E ++++V+ + + L +E LQ DV++ ++
Sbjct: 3315 STGVTNTYNFYTDANLSEARRLIEVVHKTQLKFQEL-QRVDEIGHLQPLADVVNACSRVM 3373
Query: 648 TLPSDIPLAKAFSGLQFL---LHKAQVMQENHSKFTFSNQLKSVFDLMSSWHKMELGSWP 704
L PLAK L+ L L++ Q ++ + V + + SW ++EL +W
Sbjct: 3374 ELGYADPLAKMLPSLEKLHESLYEWQFRGYASRQYIPATLYDKVTETIVSWRRLELSTWA 3433
Query: 705 VLLDEVMDQYENNAKKSVLSSSIHYF*SINFPKSNFYFSYESCS--------LEDFIQTS 756
L D + + +A + Y I P S + + LE + S
Sbjct: 3434 RLFDSELQKCREDADSWYF---VAYQAVIAGPLSLMEKGVDLRTHAPALLEELEQYFANS 3490
Query: 757 SFGEFRKRLQLLYAFLGQNHTSACLKINSSNIVFFLHCWTLQLLSDGAVNILVQYVWILC 816
GEF RL +L F Q H + L L + D N L Y
Sbjct: 3491 ILGEFTTRLNMLKQF--QAHLD----------LLALDYPQLAAIRDALRNFLTFYARFEI 3538
Query: 817 AVLTNHIDASRKEILTELKDLVKLCRWEQDKSYSSIENLKKSRQKLKKLIKKHTDILQEP 876
T I R + +KD++ + W+ + E+ +KS KL +L++K +L +P
Sbjct: 3539 KA-TEAIQRGRASLEKTMKDVLLMASWKDTNVVALRESSRKSHLKLFRLVRKFRAVLGQP 3597
Query: 877 MDKLIRD 883
M +I D
Sbjct: 3598 MRPIIVD 3604
Score = 58.2 bits (139), Expect = 3e-06
Identities = 104/536 (19%), Positives = 195/536 (35%), Gaps = 83/536 (15%)
Query: 1500 EMGPTGPDSEAVGEKIWDQNEDETPDDTGEKYESGPSVKDGDGSNKELRAKDDSTSDQSG 1559
++G + D + G + + DET D G K E G + DG+G+ E +KD +
Sbjct: 4113 QLGKSFLDIASHGFCMPQEKSDETSGDKG-KMEGGTGLGDGEGA--ENISKDIGEDEDLS 4169
Query: 1560 DDSCDEGDAQNDEAAAQNEFDDEENGDDVNMDKEAAHSDATGLKPDEPD-------HSSD 1612
+ + + QN+E + DDEE+ D+ D+ + G DE D +
Sbjct: 4170 ELAQEPNQQQNNE-----DMDDEEDAIDMGTDEMEGDLASVGGGDDEQDGERSGDEDGDE 4224
Query: 1613 MEIDLNAN--EDVDPI-----------EEGDQEGHDDSAENGNQEDE-------TCPPDE 1652
E+D A +D+DP EE D++ D+A Q+DE T
Sbjct: 4225 DEMDEQAGDVDDLDPTAVDEKMWNDDGEEADKDQRGDAASGKQQKDEEVGATDSTAKQAA 4284
Query: 1653 IMEEAHTEVDVSSEKDDLGQEHQE---NDDMNSMDPKNDTSESSDVVNPQVSNVDL---- 1705
++ + ++ G + +E +++N D + ES + P +D
Sbjct: 4285 EQQQGEEPAEAEEAGEEAGPQEEEAKPQEELNRQD--QNVQESEALALPDEMELDRDDDD 4342
Query: 1706 ------ASQSKSDLQTSGSENIASQSNLSNSHHDFGN--------PAVTGGFPSSDMSEM 1751
DL ++ Q ++S +D+G+ P G SE
Sbjct: 4343 GDGDDDDGDDLDDLPELENDQAEPQGMETDSDNDYGDDKDDITEAPKEAEGIEDEIASED 4402
Query: 1752 DINMSDSSNTGGFSK--TQPKSHLPQHEHSFSQEKQTNPSRSTGDALDFRKEKINVS--- 1806
++ + D G + PK + ++EK++ ++ A D + N +
Sbjct: 4403 EMGIDDEDIGRGEDQMDEDPKDEAETDDPDAAKEKESGTDQN--QARDNNADPENAASSD 4460
Query: 1807 -----GDLPEDNIEHHGEMDDNNADEYGYVSEFEKGTTQALGPATLEQVDRNIDVDKVDT 1861
G DN + + E NA + + G Q A+ + + + D
Sbjct: 4461 VKSGGGQDQHDNQQDNSEETQENAGQRDQGDITDPGAEQNTSAASQGRASGREEAPQPDA 4520
Query: 1862 ESRA--GEDANLQLEKQNSEIDSVSNSSLLPKNEKRDQANMPVMEKSQDDGSVKPLGSAN 1919
E A E L +K ++ ++ + +DQ ++Q+ P A
Sbjct: 4521 EQGADSAEQETLPFKKLGDLLEKWYRNNKDIREATKDQDEADTKRQAQE-----PRDQAA 4575
Query: 1920 IDPESHLED-LISISRSYLGENTHKLSQ-----LSVNDEELGKYHEPCDAPDHVKD 1969
D HL+D LG T + ++ +++++E +P PD ++D
Sbjct: 4576 TDEFQHLQDETAPADTQALGAATDEEAKPIDDTMAIDEEAEADKDKPQLMPDQMED 4631
Database: uniref100
Posted date: Jan 5, 2005 1:24 AM
Number of letters in database: 848,049,833
Number of sequences in database: 2,790,947
Lambda K H
0.319 0.133 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,749,057,610
Number of Sequences: 2790947
Number of extensions: 160780197
Number of successful extensions: 733953
Number of sequences better than 10.0: 7151
Number of HSP's better than 10.0 without gapping: 1004
Number of HSP's successfully gapped in prelim test: 6629
Number of HSP's that attempted gapping in prelim test: 598804
Number of HSP's gapped (non-prelim): 47528
length of query: 2332
length of database: 848,049,833
effective HSP length: 144
effective length of query: 2188
effective length of database: 446,153,465
effective search space: 976183781420
effective search space used: 976183781420
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 83 (36.6 bits)
Medicago: description of AC148398.1