BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC146743.14 + phase: 0
(720 letters)
Database: uniref100
2,790,947 sequences; 848,049,833 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef100_Q9LNV7 F22G5.28 [Arabidopsis thaliana] 800 0.0
UniRef100_Q7XJQ9 At2g38010 protein [Arabidopsis thaliana] 756 0.0
UniRef100_Q9FIL4 Neutral ceramidase [Arabidopsis thaliana] 701 0.0
UniRef100_Q5W7F1 Neutral ceramidase [Brachydanio rerio] 527 e-148
UniRef100_Q71ME6 Neutral/alkaline ceramidase [Homo sapiens] 516 e-145
UniRef100_Q75WL6 Ceramidase [Dictyostelium discoideum] 516 e-144
UniRef100_Q5T1D5 N-acylsphingosine amidohydrolase (Non-lysosomal... 515 e-144
UniRef100_Q7QI06 ENSANGP00000018598 [Anopheles gambiae str. PEST] 514 e-144
UniRef100_UPI000024831D UPI000024831D UniRef100 entry 509 e-143
UniRef100_UPI00002D197B UPI00002D197B UniRef100 entry 504 e-141
UniRef100_Q9JHE3 Nerutal ceramidase [Mus musculus] 504 e-141
UniRef100_Q8BNP0 Mus musculus 4 days neonate male adipose cDNA, ... 504 e-141
UniRef100_Q91XT9 Ceramidase [Rattus norvegicus] 501 e-140
UniRef100_UPI0000362C02 UPI0000362C02 UniRef100 entry 499 e-140
UniRef100_UPI0000362C01 UPI0000362C01 UniRef100 entry 479 e-133
UniRef100_Q7YTD8 Neutral ceramidase [Drosophila melanogaster] 475 e-132
UniRef100_Q9VA70 CG1471-PA, isoform A [Drosophila melanogaster] 475 e-132
UniRef100_Q86NP1 SD07768p [Drosophila melanogaster] 475 e-132
UniRef100_UPI0000432379 UPI0000432379 UniRef100 entry 461 e-128
UniRef100_UPI000045638E N-acylsphingosine amidohydrolase (Non-ly... 456 e-126
>UniRef100_Q9LNV7 F22G5.28 [Arabidopsis thaliana]
Length = 808
Score = 800 bits (2067), Expect = 0.0
Identities = 421/734 (57%), Positives = 514/734 (69%), Gaps = 59/734 (8%)
Query: 22 TYGEYLIGVGSYDMTGPAADVNMMGYANIEQNTAGIHFRLRARTFIVAENLQGPRFVFVN 81
++ EYLIG+GSYD+TGPAADVNMMGYAN+EQ +GIHFRLRARTFIV+E QG R VFVN
Sbjct: 34 SHSEYLIGLGSYDITGPAADVNMMGYANMEQVASGIHFRLRARTFIVSEP-QGKRVVFVN 92
Query: 82 LDAGMASQLLTIKLLERLKSRFGNLYTEENVAISGIHTHAGPGGYLQYVVYSVTSLGFVT 141
LDA MASQ++ +K++ERLK+R+G+LYTE+NV ISGIHTHAGPGGYLQYVVY VTSLGFV
Sbjct: 93 LDACMASQIVKLKVIERLKARYGDLYTEQNVGISGIHTHAGPGGYLQYVVYIVTSLGFVR 152
Query: 142 QSFDAIANAVEQSIIQAHNNLKPGSIFINTGDVKEASINRSPSAYLLNPAEERSRYPSNV 201
QSFDA+ + +E SIIQAH NL+PGSIF+N G++ +A +NRSPSAYL NP++ERS++ NV
Sbjct: 153 QSFDALVDGIENSIIQAHENLRPGSIFLNNGELLDAGVNRSPSAYLNNPSKERSKHKYNV 212
Query: 202 DTQMTLLKFVDSASGKSKGSFSWFATHGTSMSNNNKLISGDNKDIG-------------- 247
D +MTLLKFVD G GSF+WFATHGTSMS N LISGDNK
Sbjct: 213 DKEMTLLKFVDDQWGPV-GSFNWFATHGTSMSRTNSLISGDNKGAASRFMEDWYEQNTAE 271
Query: 248 ----------------------------ELVQIAQLIKATGGKDCNEKSSQASKVR---- 275
EL+++A ++ GK SS A +VR
Sbjct: 272 RSYSEEFISDEIPRRVSSLIENHQDSHHELLELASYFESQPGKPVTRISSSARRVRSALR 331
Query: 276 KNDGSLFVGAFCQSNVGDVSPNVLGAFCIDSGKPCDFNHSSCNGNDLLCVGRGPGYPNEI 335
K D FV AFCQ+N GDVSPNVLGAFC+D+G PCDFNHS+C G + +C GRGPGYP+E
Sbjct: 332 KADKPGFVSAFCQTNCGDVSPNVLGAFCLDTGLPCDFNHSTCGGKNEMCYGRGPGYPDEF 391
Query: 336 LSTKIIGERQFRSAVELFGSASEELTGKIDYRHVYLNFTNIEVELDNK----KVVKTCPA 391
ST+IIGERQF+ A+ELF ASE+L GK+DYRHVY++F+ + V L K +VVKTCPA
Sbjct: 392 ESTRIIGERQFKMALELFNKASEQLQGKVDYRHVYVDFSQLNVTLPKKDGKSEVVKTCPA 451
Query: 392 ALGPGFAAGTTDGPGVFGFQQGDPEISPFWKNVRDFLKEPSQYQVDCQNPKPVLLSSGEM 451
A+G FAAGTTDGPG F F QGD + +PFW+ VR+ LK P + Q+DC PKP+LL +GEM
Sbjct: 452 AMGFAFAAGTTDGPGAFDFTQGDDKGNPFWRLVRNVLKTPDKKQIDCHYPKPILLDTGEM 511
Query: 452 FDPYPWAPAILPIQILRLGKLIILSVPGEFTTMAGRRLREAVKETLISNSNGEFNNETHV 511
PY WAP+IL +Q+LR+G+L ILSVPGEFTTMAGRRLR AVK L ++ N + + E HV
Sbjct: 512 TKPYDWAPSILSLQVLRIGQLFILSVPGEFTTMAGRRLRYAVKTQLKNSGNKDLSGEIHV 571
Query: 512 VIAGLTNTYSQYIATFEEYHQQRYEAASTLYGPHTLSAYIQEFNKLAQAMAKGDKIYGNG 571
VIAGL N YSQY+ TFEEY QRYE ASTLYGPHTLS YIQEF KL++++ D G
Sbjct: 572 VIAGLANGYSQYVTTFEEYQVQRYEGASTLYGPHTLSGYIQEFKKLSKSLVL-DMPVQPG 630
Query: 572 TSPPDLLSVQKSFLLDPFGDTTPDGIKLGDIKEDIAFPGSGYFTKGD-KPSATFWSANPR 630
PPDLL Q SFL DTTP G GD+ D+ P + +G+ + + F SA PR
Sbjct: 631 PQPPDLLDKQLSFLTPVMMDTTPSGDSFGDVISDV--PKNLSLKRGNGQVTVVFRSACPR 688
Query: 631 YDLLTEGTYAVVERLQ--GERWISVQDDDDLSLFFRW-KVDNTSFHGFAAIEWEIPTDAI 687
DLLTEGT+ +VERL+ + W V DDDDL L F+W + S A +EW IP A
Sbjct: 689 NDLLTEGTFTLVERLEQKDKTWTPVYDDDDLCLRFKWSRHKKLSSRSQATVEWRIPESAS 748
Query: 688 SGVYRLKHFGASKK 701
GVYR+ HFGA+KK
Sbjct: 749 PGVYRITHFGAAKK 762
>UniRef100_Q7XJQ9 At2g38010 protein [Arabidopsis thaliana]
Length = 715
Score = 756 bits (1952), Expect = 0.0
Identities = 403/744 (54%), Positives = 492/744 (65%), Gaps = 91/744 (12%)
Query: 19 MQSTYGEYLIGVGSYDMTGPAADVNMMGYANIEQNTAGIHFRLRARTFIVAENLQGPRFV 78
+ T YLIGVGSYD+TGPAADVNMMGYAN +Q +GIHFRLRAR FIVAE
Sbjct: 19 LSRTVYAYLIGVGSYDITGPAADVNMMGYANSDQIASGIHFRLRARAFIVAEP------- 71
Query: 79 FVNLDAGMASQLLTIKLLERLKSRFGNLYTEENVAISGIHTHAGPGGYLQYVVYSVTSLG 138
E+NVAISGIHTHAGPGGYLQYV Y VTSLG
Sbjct: 72 -----------------------------QEKNVAISGIHTHAGPGGYLQYVTYIVTSLG 102
Query: 139 FVTQSFDAIANAVEQSIIQAHNNLKPGSIFINTGDVKEASINRSPSAYLLNPAEERSRYP 198
FV QSFD + N +EQSI+QAH +L+PGS F+N GD+ +A +NRSPS+YL NPA ERS+Y
Sbjct: 103 FVRQSFDVVVNGIEQSIVQAHESLRPGSAFVNKGDLLDAGVNRSPSSYLNNPAAERSKYK 162
Query: 199 SNVDTQMTLLKFVDSASGKSKGSFSWFATHGTSMSNNNKLISGDNKDIG----------- 247
+VD +MTL+KFVDS G + GSF+WFATHGTSMS N LISGDNK
Sbjct: 163 YDVDKEMTLVKFVDSQLGPT-GSFNWFATHGTSMSRTNSLISGDNKGAAARFMEDWFENG 221
Query: 248 --------------------------ELVQIAQLIKATGGKDCNEKSSQASKVRKNDGSL 281
L+ IA K++ G ++ ++VR
Sbjct: 222 QKNSVSSRNIPRRVSTIVSDFSRNQSRLLDIAATYKSSRGHSVDKSLDVKTRVRNGSKRK 281
Query: 282 FVGAFCQSNVGDVSPNVLGAFCIDSGKPCDFNHSSCNGNDLLCVGRGPGYPNEILSTKII 341
FV AFCQSN GDVSPN LG FCID+G PCDFNHS+CNG + LC GRGPGYP+E ST+II
Sbjct: 282 FVSAFCQSNCGDVSPNTLGTFCIDTGLPCDFNHSTCNGQNELCYGRGPGYPDEFESTRII 341
Query: 342 GERQFRSAVELFGSASEELTGKIDYRHVYLNFTNIEVEL----DNKKVVKTCPAALGPGF 397
GE+QF+ AVELF A+E+L GKI Y+H YL+F+N++V + + VKTCPAA+G GF
Sbjct: 342 GEKQFKMAVELFNKATEKLQGKIGYQHAYLDFSNLDVTVPKAGGGSETVKTCPAAMGFGF 401
Query: 398 AAGTTDGPGVFGFQQGDPEISPFWKNVRDFLKEPSQYQVDCQNPKPVLLSSGEMFDPYPW 457
AAGTTDGPG F F+QGD + + FW+ VR+ L+ P QV CQ PKP+LL +GEM +PY W
Sbjct: 402 AAGTTDGPGAFDFKQGDDQGNVFWRLVRNVLRTPGPEQVQCQKPKPILLDTGEMKEPYDW 461
Query: 458 APAILPIQILRLGKLIILSVPGEFTTMAGRRLREAVKETLISNSNGEFNNETHVVIAGLT 517
A ILR+G+L+ILSVPGEFTTMAGRRLR+A+K LIS+ EF+N HVVIAGLT
Sbjct: 462 A-------ILRIGQLVILSVPGEFTTMAGRRLRDAIKSFLISSDPKEFSNNMHVVIAGLT 514
Query: 518 NTYSQYIATFEEYHQQRYEAASTLYGPHTLSAYIQEFNKLAQAMAKGDKIYGNGTSPPDL 577
NTYSQYIATFEEY QRYE ASTLYG HTL+AYIQEF KLA A+ G + G PPDL
Sbjct: 515 NTYSQYIATFEEYEVQRYEGASTLYGRHTLTAYIQEFKKLATALVNGLTL-PRGPQPPDL 573
Query: 578 LSVQKSFLLDPFGDTTPDGIKLGDIKEDIAFPGSGYFTKGDKPSATFWSANPRYDLLTEG 637
L Q S L D+TP G+K GD+K D+ P F +G + +ATFWS PR DL+TEG
Sbjct: 574 LDKQISLLSPVVVDSTPLGVKFGDVKADV--PPKSTFRRGQQVNATFWSGCPRNDLMTEG 631
Query: 638 TYAVVERL-QGERWISVQDDDDLSLFFRW-KVDNTSFHGFAAIEWEIPTDAISGVYRLKH 695
++AVVE L +G +W V DDDD SL F+W + S A IEW +P A++GVYR++H
Sbjct: 632 SFAVVETLREGGKWAPVYDDDDFSLKFKWSRPAKLSSESQATIEWRVPESAVAGVYRIRH 691
Query: 696 FGASKKTIVSPINYFTGASSAFAV 719
+GAS K++ I+ F+G+SSAF V
Sbjct: 692 YGAS-KSLFGSISSFSGSSSAFVV 714
>UniRef100_Q9FIL4 Neutral ceramidase [Arabidopsis thaliana]
Length = 705
Score = 701 bits (1809), Expect = 0.0
Identities = 393/746 (52%), Positives = 485/746 (64%), Gaps = 87/746 (11%)
Query: 6 IITVLGLVCFWSWMQSTYGEYLIGVGSYDMTGPAADVNMMGYANIEQNTAGIHFRLRART 65
++ +L L C +S +YL+G+GSYD+TGPAADVNMMGYAN+EQ +G+HFRLRAR
Sbjct: 14 LLFLLRLTCIFS-----DSDYLMGLGSYDITGPAADVNMMGYANMEQVASGVHFRLRARA 68
Query: 66 FIVAENLQGPRFVFVNLDAGMASQLLTIKLLERLKSRFGNLYTEENVAISGIHTHAGPGG 125
FIVAE + ENVAISG HTHAGPGG
Sbjct: 69 FIVAEPYK------------------------------------ENVAISGTHTHAGPGG 92
Query: 126 YLQYVVYSVTSLGFVTQSFDAIANAVEQSIIQAHNNLKPGSIFINTGDVKEASINRSPSA 185
YLQY++Y VTSLGFV QSF+A+ + +EQSIIQAH NL+PGSI IN G++ +A +NRSPSA
Sbjct: 93 YLQYILYLVTSLGFVHQSFNALVDGIEQSIIQAHENLRPGSILINKGELLDAGVNRSPSA 152
Query: 186 YLLNPAEERSRYPSNVDTQMTLLKFVDSA--------SGKSKGSFS-----WFATHGTSM 232
YL NPA ERS+Y +VD +MTL+KFVD G +KG+ + WF
Sbjct: 153 YLNNPAHERSKYEYDVDKEMTLVKFVDDQWGPVGSFNCGDNKGTAARIMEDWFERENGCR 212
Query: 233 SNN-------NKLISGDNKDIGELVQIAQLIKATGGKDCNEKSSQASKVRKN----DGSL 281
S + + +IS + +L+++A + +TGGK SS A +VR D
Sbjct: 213 SVDVESPRRVSSIISDPYGEHQDLMEMASSLLSTGGKTVTRMSSVARRVRSRFRHADKPR 272
Query: 282 FVGAFCQSNVGDVSPNVLGAFCIDSGKPCDFNHSSCNGNDLLCVGRGPGYPNEILSTKII 341
FV AFCQ+N GDVSPNVLGAFCID+G PC+FN S+C G + C GRGPGYP+E ST+II
Sbjct: 273 FVSAFCQTNCGDVSPNVLGAFCIDTGLPCEFNQSTCGGKNEQCYGRGPGYPDEFESTRII 332
Query: 342 GERQFRSAVELFGSASEELTGKIDYRHVYLNFTNIEVELDNK----KVVKTCPAALGPGF 397
GERQF+ A +LF ASEE+ GK+DYRH Y++F+ +EV ++ + +VVKTCPAA+G GF
Sbjct: 333 GERQFKKAADLFTKASEEIQGKVDYRHAYVDFSQLEVTINGQNGGSEVVKTCPAAMGFGF 392
Query: 398 AAGTTDGPGVFGFQQGDPEISPFWKNVRDFLKEPSQYQVDCQNPKPVLLSSGEMFDPYPW 457
AAGTTDGPG F F+QGD + +PFW+ VR+ LK P++ QV CQ PKP+LL +GEM PY W
Sbjct: 393 AAGTTDGPGAFDFKQGDDQGNPFWRLVRNLLKNPTEEQVRCQRPKPILLDTGEMKQPYDW 452
Query: 458 APAILPIQILRLGKLIILSVPGEFTTMAGRRLREAVKETLISNSNGEFNNETHVVIAGLT 517
A ILR+G+L+IL VPGEFTTMAGRRLR+AVK L SNG E VVIAGLT
Sbjct: 453 A-------ILRIGQLVILCVPGEFTTMAGRRLRDAVKTVLKEGSNG---REFSVVIAGLT 502
Query: 518 NTYSQYIATFEEYHQQRYEAASTLYGPHTLSAYIQEFNKLAQAMAKGDKIYGNGTSPPDL 577
N+YSQYIATFEEY QRYE ASTLYGPHTLS YIQEF KLA + + G PPDL
Sbjct: 503 NSYSQYIATFEEYQVQRYEGASTLYGPHTLSGYIQEFKKLANDLLSA-QTTDPGPQPPDL 561
Query: 578 LSVQKSFLLDPFGDTTPDGIKLGDIKEDIAFPGSGYFTKG-DKPSATFWSANPRYDLLTE 636
L Q S L D TP G GD+ D+ P F KG D F SANPR DL+TE
Sbjct: 562 LHKQISLLTPVVADMTPIGTAFGDVTSDV--PRLSKFRKGADIVRVQFRSANPRNDLMTE 619
Query: 637 GTYAVVER-LQG-ERWISVQDDDDLSLFFRW-KVDNTSFHGFAAIEWEIPTDAISGVYRL 693
GT+A+VER L+G E W+ V DDDD L F+W + S A IEW IP A GVYR+
Sbjct: 620 GTFALVERWLEGRETWVPVYDDDDFCLRFKWSRPFKLSTQSTATIEWRIPETASPGVYRI 679
Query: 694 KHFGASKKTIVSPINYFTGASSAFAV 719
HFG S KT +S I++F+G+SSAF V
Sbjct: 680 THFG-SAKTPISSIHHFSGSSSAFVV 704
>UniRef100_Q5W7F1 Neutral ceramidase [Brachydanio rerio]
Length = 743
Score = 527 bits (1358), Expect = e-148
Identities = 301/704 (42%), Positives = 408/704 (57%), Gaps = 38/704 (5%)
Query: 26 YLIGVGSYDMTGPAADVNMMGYANIEQNTAGIHFRLRARTFIVAENLQGPRFVFVNLDAG 85
YLIGVG D TGP AD+ MMGYAN +Q G+H RL +R FIV + R VFV D G
Sbjct: 61 YLIGVGRADCTGPVADLPMMGYANTDQTARGLHTRLFSRAFIVDDG--NKRVVFVTSDIG 118
Query: 86 MASQLLTIKLLERLKSRFGNLYTEENVAISGIHTHAGPGGYLQYVVYSVTSLGFVTQSFD 145
M SQ L +++ + LK ++G+LY ++NV +SG HTH+G GGY QY ++ +TS G++ S
Sbjct: 119 MVSQRLRLEVFQALKEKYGDLYRQDNVVLSGTHTHSGVGGYFQYTLFMITSKGYIKPSIQ 178
Query: 146 AIANAVEQSIIQAHNNLKPGSIFINTGDVKEASINRSPSAYLLNPAEERSRYPSNVDTQM 205
AI + + +SI AH NL+PG IFIN G V +++ NRSP +Y+ NP EER+RY N D Q+
Sbjct: 179 AIVSGIVKSIDIAHRNLRPGRIFINKGQVADSNFNRSPHSYMNNPEEERNRYEFNTDKQI 238
Query: 206 TLLKFVDSASGKSKGSFSWFATHGTSMSNNNKLISGDNKDIGELVQIAQLIKATGGKDCN 265
+LKF D G G SWFA H SM+ N+++S DN +G I + K G
Sbjct: 239 VVLKFTD-LDGDGIGLLSWFAVHPVSMNYTNRMVSSDN--LGYASYIFEQEKNIG----- 290
Query: 266 EKSSQASKVRKNDGSLFVGAFCQSNVGDVSPNVLGAFCIDSGKPCDFNHSSCN-GNDLLC 324
+ FV F SN+GD SPN+ G C+++G CD+ +SSC G C
Sbjct: 291 --------FLPGEKGPFVAGFSSSNLGDSSPNIRGPVCVNTGLKCDYINSSCPVGGKKAC 342
Query: 325 VGRGPGYPNEILSTKIIGERQFRSAVELFGSASEELTGKIDYRHVYLNFTNIEVELDNKK 384
+ GPG + ST+IIGE F+ A EL+GSA +EL G + H ++N T+ V+ ++
Sbjct: 343 IAFGPG-EDMFESTRIIGENMFKIAKELYGSAKQELHGPVYGAHQWVNMTDETVQFNSTH 401
Query: 385 VVKTCPAALGPGFAAGTTDGPGVFGFQQGDPEISPFWKNVRD-FLKEPSQYQVDCQNPKP 443
+TC ALG FAAGTTDG G F F QGD E PFW +RD L PS C PKP
Sbjct: 402 TGRTCKPALGHSFAAGTTDGGGEFNFLQGDTEGDPFWDGIRDAVLGPPSNETKACHQPKP 461
Query: 444 VLLSSGEMFDPYPWAPAILPIQILRLGKLIILSVPGEFTTMAGRRLREAVKETLISNSNG 503
+L S+GEM P PW PAI+ +QI+ +G L +++VPGEFTTM+GRR+REAVK L
Sbjct: 462 ILFSTGEMDSPLPWHPAIVDVQIITIGSLAVVAVPGEFTTMSGRRIREAVKREL--EVKE 519
Query: 504 EFNNETHVVIAGLTNTYSQYIATFEEYHQQRYEAASTLYGPHTLSAYIQEFNKLAQAMAK 563
F N VV+AGL N Y+ YI T+EEY QRYE AST++GPHTLSAYIQ + LA+A+A
Sbjct: 520 PFTN-AEVVVAGLCNIYTHYITTYEEYQIQRYEGASTIFGPHTLSAYIQRYRGLAKAIAH 578
Query: 564 GD-KIYGNGTSPPDLLSVQKSF--LLDPFGDTTPDGIKLGDIKEDIAFPGSGYFTKGDKP 620
G G PP K F + DP D P G GD+ +++ + + G+
Sbjct: 579 GTIGELPKGPEPP-FFDEDKLFNQVRDPVADVAPVGTTFGDVLQEV----NPVYKVGEIA 633
Query: 621 SATFWSANPRYD-LLTEGTYAVVERLQGE--RWISVQDDDDLSLFFRWKVDNTSFHGFAA 677
S TF S NPR+ + + T VER + W + +D F W + + A
Sbjct: 634 SVTFVSGNPRHSGDIRDTTLVTVERFHNDTGSWEIIHNDASWETRFHW-IKGLAGRSQAK 692
Query: 678 IEWEIPTDAISGVYRLKHFGASKKTI--VSPINYFTGASSAFAV 719
+EW IP A +G Y++++FG K+T + I + G S+AF V
Sbjct: 693 VEWHIPQTAQAGTYQIQYFGHYKQTTENTTVITPYVGTSAAFKV 736
>UniRef100_Q71ME6 Neutral/alkaline ceramidase [Homo sapiens]
Length = 779
Score = 516 bits (1329), Expect = e-145
Identities = 306/713 (42%), Positives = 411/713 (56%), Gaps = 50/713 (7%)
Query: 23 YGEYLIGVGSYDMTGPAADVNMMGYANIEQNTAGIHFRLRARTFIVAENLQGPRFVFVNL 82
+ Y IGVG D TG AD+N+MGY QN GI RL +R FI+AE R VFV++
Sbjct: 98 FSGYHIGVGRADCTGQVADINLMGYGKSGQNAQGILTRLYSRAFIMAEPDGSNRTVFVSI 157
Query: 83 DAGMASQLLTIKLLERLKSRFGNLYTEENVAISGIHTHAGPGGYLQYVVYSVTSLGFVTQ 142
D GM SQ L +++L RL+S++G+LY +NV +SG HTH+GP GY QY V+ + S GF Q
Sbjct: 158 DIGMVSQRLRLEVLNRLQSKYGSLYRRDNVILSGTHTHSGPAGYFQYTVFVIASEGFSNQ 217
Query: 143 SFDAIANAVEQSIIQAHNNLKPGSIFINTGDVKEASINRSPSAYLLNPAEERSRYPSNVD 202
+F + + +SI AH N+KPG IFIN G+V INRSP +YL NP ER+RYPSN D
Sbjct: 218 TFQHMVTGILKSIDIAHTNMKPGKIFINKGNVDGVQINRSPYSYLQNPQSERARYPSNTD 277
Query: 203 TQMTLLKFVDSASGKSKGSFSWFATHGTSMSNNNKLISGDNKDIGELVQIAQLIKATGGK 262
+M +LK VD +G G SWFA H SM+N+N L++ DN +G
Sbjct: 278 KEMIVLKMVD-LNGDDLGLISWFAIHPVSMNNSNHLVNSDN--VG--------------- 319
Query: 263 DCNEKSSQASKVRKNDGSL-----FVGAFCQSNVGDVSPNVLGAFCIDSGKPCDFNHSSC 317
+S + KN G L FV AF SN+GDVSPN+LG CI++G+ CD +S+C
Sbjct: 320 ----YASYLLEQEKNKGYLPGQGPFVAAFASSNLGDVSPNILGPRCINTGESCDNANSTC 375
Query: 318 N-GNDLLCVGRGPGYPNEILSTKIIGERQFRSAVELFGSASEELTGKIDYRHVYLNFTNI 376
G +C+ +GPG + ST+IIG ++ A EL+ SAS+E+TG + H +++ T++
Sbjct: 376 PIGGPSMCIAKGPG-QDMFDSTQIIGRAMYQRAKELYASASQEVTGPLASAHQWVDMTDV 434
Query: 377 EVELDNKKVVKTCPAALGPGFAAGTTDGPGVFGFQQGDPEISPFWKNVRD-FLKEPSQYQ 435
V L++ KTC ALG FAAGT DG G F QG E PFW +RD L +PS+
Sbjct: 435 TVWLNSTHASKTCKPALGYSFAAGTIDGVGGLNFTQGKTEGDPFWDTIRDQILGKPSEEI 494
Query: 436 VDCQNPKPVLLSSGEMFDPYPWAPAILPIQILRLGKLIILSVPGEFTTMAGRRLREAVKE 495
+C PKP+LL +GE+ P+PW P I+ +QI+ LG L I ++PGEFTTM+GRRLREAV+
Sbjct: 495 KECHKPKPILLHTGELSKPHPWHPDIVDVQIITLGSLAITAIPGEFTTMSGRRLREAVQA 554
Query: 496 TLISNSNGEFNNETHVVIAGLTNTYSQYIATFEEYHQQRYEAASTLYGPHTLSAYIQEFN 555
S+ N T VVI+GL N Y+ YI T+EEY QRYEAAST+YGPH LSAYIQ F
Sbjct: 555 EFASHG---MQNMT-VVISGLCNVYTHYITTYEEYQAQRYEAASTIYGPHALSAYIQLFR 610
Query: 556 KLAQAMAKGDKI--YGNGTSPPDLLSVQKSFLLDPFGDTTPDGIKLGDIKEDIAFPGSGY 613
LA+A+A D + G PP + L+ D P G GD+ + P
Sbjct: 611 NLAKAIAT-DTVANLSRGPEPPFFKQLIVP-LIPSIVDRAPKGRTFGDVLQ----PAKPE 664
Query: 614 FTKGDKPSATFWSANPRYDL--LTEGTYAVVERLQ--GERWISVQDDDDLSLFFRWKVDN 669
+ G+ F ANP+ + T T+ VE+ + W V +D F W
Sbjct: 665 YRVGEVAEVIFVGANPKNSVQNQTHQTFLTVEKYEATSTSWQIVCNDASWETRFYWHKGL 724
Query: 670 TSFHGFAAIEWEIPTDAISGVYRLKHFGASKK-TIVSP--INYFTGASSAFAV 719
A +EW IP A G+YR+++FG ++K I+ P I F G S AF V
Sbjct: 725 LGLSN-ATVEWHIPDTAQPGIYRIRYFGHNRKQDILKPAVILSFEGTSPAFEV 776
>UniRef100_Q75WL6 Ceramidase [Dictyostelium discoideum]
Length = 714
Score = 516 bits (1328), Expect = e-144
Identities = 290/703 (41%), Positives = 414/703 (58%), Gaps = 36/703 (5%)
Query: 26 YLIGVGSYDMTGPAADVNMMGYANIEQNTAGIHFRLRARTFIVAENLQGPRFVFVNLDAG 85
Y IG G YD+TGP A+ NMMGYA Q T GIHFR RAR F+ ++ +G R V+V+ D+
Sbjct: 40 YQIGTGIYDITGPGAETNMMGYAMPGQITGGIHFRQRARAFVFIDS-EGNRAVYVSTDSC 98
Query: 86 MASQLLTIKLLERLKSRFG-NLYTEENVAISGIHTHAGPGGYLQYVVYSVTSLGFVTQSF 144
M Q + I++++ L+ FG LYT +NV +SG HTH+GP G+ +Y +Y +T+LGF ++F
Sbjct: 99 MIFQEVKIQVIQDLQEIFGPTLYTHDNVLLSGTHTHSGPAGFSEYALYGITALGFYKKNF 158
Query: 145 DAIANAVEQSIIQAHNNLKPGSIFINTGDVKEASINRSPSAYLLNPAEERSRYPSNVDTQ 204
D I + + Q+I++AH +++P + G++ ++INRSP AY NP EE++ Y +NVD
Sbjct: 159 DTICDGIVQAIVKAHKSVQPARMLTQQGELWNSNINRSPYAYDNNPEEEKAMYDANVDKN 218
Query: 205 MTLLKFVDSASGKSKGSFSWFATHGTSMSNNNKLISGDNKDIGELVQIAQLIKATGGKDC 264
MT+++ ++ SG + S+F H TSM+N N LISGDNK +
Sbjct: 219 MTVIR-IEDMSGNPFAAISFFGVHCTSMNNTNHLISGDNKGYASYLW------------- 264
Query: 265 NEKSSQASKVRKNDGSLFVGAFCQSNVGDVSPNVLGAFCIDSGKPCDFNHSSCNGNDLLC 324
EK + G F+ AF QSN GDVSPN G C D GKPCD+ S+CNG C
Sbjct: 265 -EKHANGQSSLPGTGP-FIAAFGQSNEGDVSPNTRGPTCRD-GKPCDYKTSTCNGKVEEC 321
Query: 325 VGRGPGYPNEIL-STKIIGERQFRSAVELFGSASEELTGKIDYRHVYLNFTNIEVELDNK 383
GPG ++ ST+IIG QF A+ELF +A+ +++GKI YRH + FTN+ VE
Sbjct: 322 WALGPGTDGDMFESTQIIGGNQFNKALELFNNATIQVSGKIQYRHTWKPFTNVSVEAPYN 381
Query: 384 KVVK---TCPAALGPGFAAGTTDGPGVFGFQQGD-PEISPFWKNVRDFLKEPSQYQVDCQ 439
V+ TC A+G FA GTTDGPG F F QGD +PFW + + +P+ Q CQ
Sbjct: 382 SGVEGATTCRGAMGYSFAGGTTDGPGAFNFIQGDNSTTNPFWNFIGGIIAKPTPQQTACQ 441
Query: 440 NPKPVLLSSGEMFDPYPWAPAILPIQILRLGKLIILSVPGEFTTMAGRRLREAVKETLIS 499
PKP+L+ G M +P PW P ++P+QI+ LG++++++VPGEFTTM+GRRLR V+E +
Sbjct: 442 APKPILIDVG-MVEPIPWVPDVMPLQIITLGQIVLVAVPGEFTTMSGRRLRNTVREII-- 498
Query: 500 NSNGEFNNETHVVIAGLTNTYSQYIATFEEYHQQRYEAASTLYGPHTLSAYIQEFNKLAQ 559
G+ V+IAGL NTYS YIATFEE+ QRYE AST++GPHTL AY QEF LAQ
Sbjct: 499 ---GQSIENPIVLIAGLANTYSGYIATFEEFQVQRYEGASTVFGPHTLGAYQQEFANLAQ 555
Query: 560 AMAKGDKIYGNGTSPPDLLSVQKSFLLDPFGDTTPDGIKLGDIKEDIAFPGSGYFTKGDK 619
++ G + GT P ++ FL D P GDI D++ + ++
Sbjct: 556 SIVDGSQA-DPGTFPRNMSGHTPFFLPPVIVDVAPKFDDFGDIYTDVS--TTTPYSINQT 612
Query: 620 PSATFWSANPRYDLLTEGTYAVVERLQGE-RWISVQDDDDLSLFFRWKVDNTSFHGFAAI 678
+ F+ AN R + +TE ++ V++LQ +W ++ +D D WK+ + F +
Sbjct: 613 VTVIFYGANLRNNFMTESSFLTVDQLQSNGQWTTILNDGDWDTKLYWKMHDLGF-SLITV 671
Query: 679 EWEIPTDAISGVYRLKHFGASKKTIVSP-INYFTGASSAFAVQ 720
+W I G YR+ H G +KK S + ++ G SS F VQ
Sbjct: 672 DWTISPITQPGTYRITHSGYAKKNPFSDNLTFYQGISSNFNVQ 714
>UniRef100_Q5T1D5 N-acylsphingosine amidohydrolase (Non-lysosomal ceramidase) 2 [Homo
sapiens]
Length = 761
Score = 515 bits (1326), Expect = e-144
Identities = 306/713 (42%), Positives = 411/713 (56%), Gaps = 50/713 (7%)
Query: 23 YGEYLIGVGSYDMTGPAADVNMMGYANIEQNTAGIHFRLRARTFIVAENLQGPRFVFVNL 82
+ Y IGVG D TG AD+N+MGY QN GI RL +R FI+AE R VFV++
Sbjct: 80 FSGYHIGVGRADCTGQVADINLMGYGKSGQNAQGILTRLYSRAFIMAEPDGSNRTVFVSI 139
Query: 83 DAGMASQLLTIKLLERLKSRFGNLYTEENVAISGIHTHAGPGGYLQYVVYSVTSLGFVTQ 142
D GM SQ L +++L RL+S++G+LY +NV +SG HTH+GP GY QY V+ + S GF Q
Sbjct: 140 DIGMVSQRLRLEVLNRLQSKYGSLYRRDNVILSGTHTHSGPAGYFQYTVFVIASEGFSNQ 199
Query: 143 SFDAIANAVEQSIIQAHNNLKPGSIFINTGDVKEASINRSPSAYLLNPAEERSRYPSNVD 202
+F + + +SI AH N+KPG IFIN G+V INRSP +YL NP ER+RY SN D
Sbjct: 200 TFQHMVTGILKSIDIAHTNMKPGKIFINKGNVDGVQINRSPYSYLQNPQSERARYSSNTD 259
Query: 203 TQMTLLKFVDSASGKSKGSFSWFATHGTSMSNNNKLISGDNKDIGELVQIAQLIKATGGK 262
+M +LK VD +G G SWFA H SM+N+N L++ DN +G
Sbjct: 260 KEMIVLKMVD-LNGDDLGLISWFAIHPVSMNNSNHLVNSDN--VG--------------- 301
Query: 263 DCNEKSSQASKVRKNDGSL-----FVGAFCQSNVGDVSPNVLGAFCIDSGKPCDFNHSSC 317
+S + KN G L FV AF SN+GDVSPN+LG CI++G+ CD +S+C
Sbjct: 302 ----YASYLLEQEKNKGYLPGQGPFVAAFASSNLGDVSPNILGPRCINTGESCDNANSTC 357
Query: 318 N-GNDLLCVGRGPGYPNEILSTKIIGERQFRSAVELFGSASEELTGKIDYRHVYLNFTNI 376
G +C+ +GPG + ST+IIG ++ A EL+ SAS+E+TG + H +++ T++
Sbjct: 358 PIGGPSMCIAKGPG-QDMFDSTQIIGRAMYQRAKELYASASQEVTGPLASAHQWVDMTDV 416
Query: 377 EVELDNKKVVKTCPAALGPGFAAGTTDGPGVFGFQQGDPEISPFWKNVRD-FLKEPSQYQ 435
V L++ KTC ALG FAAGT DG G F QG E PFW +RD L +PS+
Sbjct: 417 TVWLNSTHASKTCKPALGYSFAAGTIDGVGGLNFTQGKTEGDPFWDTIRDQILGKPSEEI 476
Query: 436 VDCQNPKPVLLSSGEMFDPYPWAPAILPIQILRLGKLIILSVPGEFTTMAGRRLREAVKE 495
+C PKP+LL +GE+ P+PW P I+ +QI+ LG L I ++PGEFTTM+GRRLREAV+
Sbjct: 477 KECHKPKPILLHTGELSKPHPWHPDIVDVQIITLGSLAITAIPGEFTTMSGRRLREAVQA 536
Query: 496 TLISNSNGEFNNETHVVIAGLTNTYSQYIATFEEYHQQRYEAASTLYGPHTLSAYIQEFN 555
S+ N T VVI+GL N Y+ YI T+EEY QRYEAAST+YGPHTLSAYIQ F
Sbjct: 537 EFASHG---MQNMT-VVISGLCNVYTHYITTYEEYQAQRYEAASTIYGPHTLSAYIQLFR 592
Query: 556 KLAQAMAKGDKI--YGNGTSPPDLLSVQKSFLLDPFGDTTPDGIKLGDIKEDIAFPGSGY 613
LA+A+A D + G PP + L+ D P G GD+ + P
Sbjct: 593 NLAKAIAT-DTVANLSRGPEPPFFKQLIVP-LIPSIVDRAPKGRTFGDVLQ----PAKPE 646
Query: 614 FTKGDKPSATFWSANPRYDL--LTEGTYAVVERLQ--GERWISVQDDDDLSLFFRWKVDN 669
+ G+ F ANP+ + T T+ VE+ + W V +D F W
Sbjct: 647 YRVGEVAEVIFVGANPKNSVQNQTHQTFLTVEKYEATSTSWQIVCNDASWETRFYWHKGL 706
Query: 670 TSFHGFAAIEWEIPTDAISGVYRLKHFGASKK-TIVSP--INYFTGASSAFAV 719
A +EW IP A G+YR+++FG ++K I+ P I F G S AF V
Sbjct: 707 LGLSN-ATVEWHIPDTAQPGIYRIRYFGHNRKQDILKPAVILSFEGTSPAFEV 758
>UniRef100_Q7QI06 ENSANGP00000018598 [Anopheles gambiae str. PEST]
Length = 696
Score = 514 bits (1324), Expect = e-144
Identities = 294/710 (41%), Positives = 422/710 (59%), Gaps = 40/710 (5%)
Query: 22 TYGEYLIGVGSYDMTGPAADVNMMGYANIEQNTAGIHFRLRARTFIVAENLQGPRFVFVN 81
T G Y +GVG D TGP+ ++ MGYA + Q GIH R AR++++ E+ G R VFV+
Sbjct: 16 TTGAYRVGVGRADCTGPSVEITFMGYAQVTQRGTGIHLRQYARSYVI-EDENGTRVVFVS 74
Query: 82 LDAGMASQLLTIKLLERLKSRFGNLYTEENVAISGIHTHAGPGGYLQYVVYSVTSLGFVT 141
+DAGM + +L L+ ++G LYT NV ISG HTH+ PGG+L Y++Y +TSLGFV
Sbjct: 75 VDAGMMGHAVKRDVLAVLQKKYGELYTHANVVISGTHTHSTPGGFLMYLLYDLTSLGFVP 134
Query: 142 QSFDAIANAVEQSIIQAHNNLKPGSIFINTGDVKEASINRSPSAYLLNPAEERSRYPSNV 201
++F+A+ + + QS+I+AHNNL +++ +V EA+INRSPSAY NP EER++Y NV
Sbjct: 135 ETFNALVHGIAQSVIRAHNNLVEARLYVAETEVLEANINRSPSAYENNPEEERAQYRHNV 194
Query: 202 DTQMTLLKFVDSASGKSKGSFSWFATHGTSMSNNNKLISGDNKDIGELVQIAQLIKATGG 261
D + L+FV + +G G+ +WFA H TSM+N N+L+S DN + ++
Sbjct: 195 DKTLVQLQFVHARTGAPFGAINWFAVHPTSMNNTNRLVSSDNVGLAAIL----------- 243
Query: 262 KDCNEKSSQASKVRKNDGSLFVGAFCQSNVGDVSPNVLGAFCIDSGKPCDFNHSSCNGND 321
++ + + V K D FVGAF SN+GDVSPN+ G C +G PCD SSC
Sbjct: 244 --LEQERNPDALVGKGD---FVGAFASSNLGDVSPNINGPKCEKTGLPCDVLTSSCPSGA 298
Query: 322 LLCVGRGPGYPNEILSTKIIGERQFRSAVELFG---SASEELTGKIDYRHVYLNFTNIE- 377
C GPG + ST+II +R +R+A L + + E+TG + + H Y++ T E
Sbjct: 299 GACFASGPG-RDMFESTEIIADRLYRAAAGLLSTRTTKAREVTGPVAFVHQYVDMTTAET 357
Query: 378 VELD---NKKV-VKTCPAALGPGFAAGTTDGPGVFGFQQGDPEISPFWKNVRDFLKEPSQ 433
V D K V V+ C A+G FAAGTTDGPG F FQQG + W VRDF+ EP+Q
Sbjct: 358 VHFDRATQKPVRVRGCLPAMGYSFAAGTTDGPGAFDFQQGTITDNVLWNAVRDFIAEPTQ 417
Query: 434 YQVDCQNPKPVLLSSGEMFDPYPWAPAILPIQILRLGKLIILSVPGEFTTMAGRRLREAV 493
DCQ PKP+LL++G PY W P ++P Q+L +G + +VPGEFTTMAGRRLR AV
Sbjct: 418 DDKDCQAPKPILLATGRARFPYDWQPKVVPTQLLVVGDFAMAAVPGEFTTMAGRRLRSAV 477
Query: 494 KETLISNSNGEFNNETHVVIAGLTNTYSQYIATFEEYHQQRYEAASTLYGPHTLSAYIQE 553
++ + VV+AGL+N YS YI T EEY QRYE ASTLYGPHTL+ Y+++
Sbjct: 478 ARASVAAG----GRDLQVVVAGLSNMYSSYITTPEEYEIQRYEGASTLYGPHTLTLYLEQ 533
Query: 554 FNKLAQAMAKGDKIYGNGTSPPDLLSVQKSFLLDPFGDTTPDGIKLGDIKEDIAFPGSGY 613
+ +LA A+ + + + G +PP Q S D+ P G + GD+K P + Y
Sbjct: 534 YKRLAGALVRNETVPA-GPTPPYEDDKQISLTTGVIFDSHPLGKEFGDVK---VHPEAAY 589
Query: 614 FTKGDKPSATFWSANPRYDLLTEGTYAVVERLQGE-RWISVQDDDDLSLFFRWKVDNTSF 672
+G SA F + NPR +L+ + ++ VE+ Q + W V D + FRW+ +T
Sbjct: 590 -ERGATVSAVFIAGNPRNNLMHDKSFFTVEQQQPDGNWSVVATDANWETRFRWERTSTIL 648
Query: 673 HGFAAIE--WEIPTDAISGVYRLKHFGASKKTIVSPINYFTGASSAFAVQ 720
GF+ IE W I + + G+YR++HFG + I+ + + GA++AF+V+
Sbjct: 649 -GFSDIEFSWTIGPNTLDGLYRIRHFG-YYRYILGGVYPYVGATNAFSVK 696
>UniRef100_UPI000024831D UPI000024831D UniRef100 entry
Length = 670
Score = 509 bits (1312), Expect = e-143
Identities = 294/704 (41%), Positives = 404/704 (56%), Gaps = 44/704 (6%)
Query: 26 YLIGVGSYDMTGPAADVNMMGYANIEQNTAGIHFRLRARTFIVAENLQGPRFVFVNLDAG 85
YLIGVG D TGP AD+ MMGYAN +Q G+H RL +R FIV + R VFV D G
Sbjct: 1 YLIGVGRADCTGPVADLPMMGYANTDQTARGLHTRLFSRAFIVDDG--NKRVVFVTSDIG 58
Query: 86 MASQLLTIKLLERLKSRFGNLYTEENVAISGIHTHAGPGGYLQYVVYSVTSLGFVTQSFD 145
M SQ L +++ + LK ++G+LY ++NV +SG HTH+G GGY QY ++ +TS G++ S
Sbjct: 59 MVSQRLRLEVFQALKEKYGDLYRQDNVVLSGTHTHSGVGGYFQYTLFMITSKGYIKPSIQ 118
Query: 146 AIANAVEQSIIQAHNNLKPGSIFINTGDVKEASINRSPSAYLLNPAEERSRYPSNVDTQM 205
AI + + +SI AH NL+PG IFIN G V +++ NRSP +Y+ NP EER+R + +
Sbjct: 119 AIVSGIVKSIDIAHRNLRPGRIFINKGQVADSNFNRSPHSYMNNPEEERNRIQYVLFMNV 178
Query: 206 TLLKFVDSASGKSKGSFSWFATHGTSMSNNNKLISGDNKDIGELVQIAQLIKATGGKDCN 265
L+ F SA FSWFA H SM+ N+++S DN +G I + K G
Sbjct: 179 MLINFYSSA-------FSWFAVHPVSMNYTNRMVSSDN--LGYASYIFEQEKNIG----- 224
Query: 266 EKSSQASKVRKNDGSLFVGAFCQSNVGDVSPNVLGAFCIDSGKPCDFNHSSCN-GNDLLC 324
+ FV F SN+GD SPN+ G C+++G CD+ +SSC G C
Sbjct: 225 --------FLPGEKGPFVAGFSSSNLGDSSPNIRGPVCVNTGLKCDYINSSCPVGGKKAC 276
Query: 325 VGRGPGYPNEILSTKIIGERQFRSAVELFGSASEELTGKIDYRHVYLNFTNIEVELDNKK 384
+ GPG + ST+IIGE F+ A EL+GSA +EL G + H ++N T+ V+ ++
Sbjct: 277 IAFGPG-EDMFESTRIIGENMFKIAKELYGSAKQELHGPVYGAHQWVNMTDETVQFNSTH 335
Query: 385 VVKTCPAALGPGFAAGTTDGPGVFGFQQGDPEISPFWKNVRD-FLKEPSQYQVDCQNPKP 443
+TC ALG FAAGTTDG G F F QG+ + PFW +RD L PS C PKP
Sbjct: 336 TGRTCKPALGHSFAAGTTDGGGEFNFLQGEEKRDPFWDGIRDAVLGPPSNETKACHQPKP 395
Query: 444 VLLSSGEMFDPYPWAPAILPIQILRLGKLIILSVPGEFTTMAGRRLREAVKETLISNSNG 503
+L S+GEM P PW PAI+ +QI+ +G L +++VPGEFTTM+GRR+REAVK L
Sbjct: 396 ILFSTGEMDSPLPWHPAIVDVQIITIGSLAVVAVPGEFTTMSGRRIREAVKREL--EVKE 453
Query: 504 EFNNETHVVIAGLTNTYSQYIATFEEYHQQRYEAASTLYGPHTLSAYIQEFNKLAQAMAK 563
F N VV+AGL N Y+ YI T+EEY QRYE AST++GPHTLSAYIQ + LA+A+A
Sbjct: 454 PFTN-AEVVVAGLCNIYTHYITTYEEYQIQRYEGASTIFGPHTLSAYIQRYRGLAKAIAH 512
Query: 564 GD-KIYGNGTSPPDLLSVQKSF--LLDPFGDTTPDGIKLGDIKEDIAFPGSGYFTKGDKP 620
G G PP K F + DP D P G GD+ +++ + + G+
Sbjct: 513 GTIGELPKGPEPP-FFDEDKLFNQVRDPVADVAPVGTTFGDVLQEV----NPVYKVGEIA 567
Query: 621 SATFWSANPRYD-LLTEGTYAVVERLQGE--RWISVQDDDDLSLFFRWKVDNTSFHGFAA 677
S TF S NPR+ + + T VER + W + +D F W + + A
Sbjct: 568 SVTFVSGNPRHSGDIRDTTLVTVERFHNDTGSWEIIHNDASWETRFHW-IKGLAGRSQAK 626
Query: 678 IEWEIPTDAISGVYRLKHFGASKKTI--VSPINYFTGASSAFAV 719
+EW IP A +G Y++++FG K+T + I + G S+AF V
Sbjct: 627 VEWHIPQTAQAGTYQIQYFGHYKQTTENTTVITPYVGTSAAFKV 670
>UniRef100_UPI00002D197B UPI00002D197B UniRef100 entry
Length = 746
Score = 504 bits (1299), Expect = e-141
Identities = 284/712 (39%), Positives = 409/712 (56%), Gaps = 48/712 (6%)
Query: 20 QSTYGEYLIGVGSYDMTGPAADVNMMGYANIEQNTAGIHFRLRARTFIVAENLQGPRFVF 79
++ + YLIGVG D TGP A++ ++ + Q +H RL +R FI+ ++ Q R VF
Sbjct: 70 ETEHKPYLIGVGRADCTGPPAEIPLVSFEPGLQAQVTVHTRLYSRAFIIDDSQQ--RVVF 127
Query: 80 VNLDAGMASQLLTIKLLERLKSRFGNLYTEENVAISGIHTHAGPGGYLQYVVYSVTSLGF 139
V D GM SQ L +++L+ LK ++GNLY ++NV +SG HTH GP GY QY ++ +TS G+
Sbjct: 128 VTADVGMVSQRLRLEVLKALKEKYGNLYRQDNVVLSGTHTHCGPAGYFQYTLFMITSKGY 187
Query: 140 VTQSFDAIANAVEQSIIQAHNNLKPGSIFINTGDVKEASINRSPSAYLLNPAEERSRYPS 199
+ +S + N + +SI AH+N+KPG I+ + GD+ +SINRSP +Y+ NP EER+RY
Sbjct: 188 IKESIQPLVNGIVKSIDLAHSNMKPGRIYRSRGDLDGSSINRSPHSYMNNPEEERNRYKW 247
Query: 200 NVDTQMTLLKFVDSASGKSKGSFSWFATHGTSMSNNNKLISGDNKDIGELVQIAQLIKAT 259
N D Q+ +LKF D G G SWFA H SM+ N+++S DN
Sbjct: 248 NTDKQVLVLKFTD-LDGDGIGMLSWFAVHAVSMNYTNRMVSSDNMGY------------- 293
Query: 260 GGKDCNEKSSQASKVRKNDGSL-----FVGAFCQSNVGDVSPNVLGAFCIDSGKPCDFNH 314
+S + KN G L FV F SN+GDV+PN G C++SG PCD+ +
Sbjct: 294 --------ASYLMEQDKNPGELPGKGGFVAGFSSSNLGDVTPNTKGPHCVNSGLPCDYLN 345
Query: 315 SSCN-GNDLLCVGRGPGYPNEILSTKIIGERQFRSAVELFGSASEELTGKIDYRHVYLNF 373
SSC G +C GPG + ST+IIG + A EL+ +A EE+TG + H +++
Sbjct: 346 SSCPVGGTKMCQSSGPG-ADMFESTRIIGHNIYMKAKELYANAKEEVTGFLQSAHQWVDM 404
Query: 374 TNIEVELDNKKVVKTCPAALGPGFAAGTTDGPGVFGFQQGDPEISPFWKNVRD-FLKEPS 432
+N+ +++++ V+TC ALG FAAGTTDG G F QG PFW +RD + +PS
Sbjct: 405 SNVTIQINSTHTVRTCKPALGHSFAAGTTDGGGDLNFTQGSVVGDPFWDGIRDAIVGKPS 464
Query: 433 QYQVDCQNPKPVLLSSGEMFDPYPWAPAILPIQILRLGKLIILSVPGEFTTMAGRRLREA 492
+C PKP+L S+GEM P PW P I+ +QI+ +G + +++VPGE TTM+GRRLRE+
Sbjct: 465 NETQECHQPKPILFSTGEMSKPLPWHPNIIDVQIITIGSVAVVAVPGEMTTMSGRRLRES 524
Query: 493 VKETLISNSNGEFNNETHVVIAGLTNTYSQYIATFEEYHQQRYEAASTLYGPHTLSAYIQ 552
VK+ L S G F + VVIAGL+N Y+ YI TFEEY QRYE AST++GP+TLSAY+Q
Sbjct: 525 VKQEL--QSEGAF-RDVEVVIAGLSNVYTHYITTFEEYQVQRYEGASTIFGPYTLSAYLQ 581
Query: 553 EFNKLAQAMAKGDKIYGNGTSPPDLLSVQKSFLLDPFGDTTPDGIKLGDIKEDIAFPGSG 612
++ LA+A+A+ + G PP + F D P+ GD+ + +P
Sbjct: 582 KYRGLARAIAQAE--LPTGPQPPFFEKLFNLMFAAGF-DRKPENRSFGDVIGQV-YP--- 634
Query: 613 YFTKGDKPSATFWSANPRYD-LLTEGTYAVVERLQG--ERWISVQDDDDLSLFFRWKVDN 669
+ +GD S TF + NPR+ + + T+ VE + W +V D F W +
Sbjct: 635 VYRQGDVVSVTFVAGNPRHSGDMRDKTFVAVEIYDNRTDTWNTVHTDASWETRFHW-LKG 693
Query: 670 TSFHGFAAIEWEIPTDAISGVYRLKHFGASK--KTIVSPINYFTGASSAFAV 719
++ + +EW IP A SG YR+KHFG K K + I + G S F V
Sbjct: 694 SNRQSNSTVEWYIPPSAASGFYRIKHFGHYKQMKGLKPVITPYEGTSDVFRV 745
>UniRef100_Q9JHE3 Nerutal ceramidase [Mus musculus]
Length = 756
Score = 504 bits (1299), Expect = e-141
Identities = 295/713 (41%), Positives = 409/713 (56%), Gaps = 50/713 (7%)
Query: 23 YGEYLIGVGSYDMTGPAADVNMMGYANIEQNTAGIHFRLRARTFIVAENLQGPRFVFVNL 82
+ Y IGVG D TG +D+N+MGY QN G+ RL +R FI+A+ R FV++
Sbjct: 75 FSGYYIGVGRADCTGQVSDINLMGYGKNGQNARGLLTRLFSRAFILADPDGSNRMAFVSV 134
Query: 83 DAGMASQLLTIKLLERLKSRFGNLYTEENVAISGIHTHAGPGGYLQYVVYSVTSLGFVTQ 142
+ M SQ L +++L+RL+S++G+LY +NV +S IHTH+GP G+ QY +Y + S GF +
Sbjct: 135 ELCMISQRLRLEVLKRLESKYGSLYRRDNVILSAIHTHSGPAGFFQYTLYILASEGFSNR 194
Query: 143 SFDAIANAVEQSIIQAHNNLKPGSIFINTGDVKEASINRSPSAYLLNPAEERSRYPSNVD 202
+F I + + +SI AH NLKPG IFIN G+V INRSPS+YLLNP ER+RY SN D
Sbjct: 195 TFQYIVSGIMKSIDIAHTNLKPGKIFINKGNVANVQINRSPSSYLLNPQSERARYSSNTD 254
Query: 203 TQMTLLKFVDSASGKSKGSFSWFATHGTSMSNNNKLISGDNKDIGELVQIAQLIKATGGK 262
+M +LK VD +G+ G SWFA H SM+N+N ++ DN
Sbjct: 255 KEMLVLKLVD-LNGEDLGLISWFAIHPVSMNNSNHFVNSDNMGY---------------- 297
Query: 263 DCNEKSSQASKVRKNDGSL-----FVGAFCQSNVGDVSPNVLGAFCIDSGKPCDFNHSSC 317
++ + KN G L FV F SN+GDVSPN+LG C+++G+ CD + S+C
Sbjct: 298 -----AAYLFEQEKNKGYLPGQGPFVAGFASSNLGDVSPNILGPHCVNTGESCDNDKSTC 352
Query: 318 -NGNDLLCVGRGPGYPNEILSTKIIGERQFRSAVELFGSASEELTGKIDYRHVYLNFTNI 376
NG +C+ GPG + ST IIG ++ A EL+ SAS+E+TG + H ++N T++
Sbjct: 353 PNGGPSMCMASGPG-QDMFESTHIIGRIIYQKAKELYASASQEVTGPVLAAHQWVNMTDV 411
Query: 377 EVELDNKKVVKTCPAALGPGFAAGTTDGPGVFGFQQGDPEISPFWKNVRD-FLKEPSQYQ 435
V+L+ VKTC ALG FAAGT DG QG E PFW +RD L +PS+
Sbjct: 412 SVQLNATHTVKTCKPALGYSFAAGTIDGVSGLNITQGTTEGDPFWDTLRDQLLGKPSEEI 471
Query: 436 VDCQNPKPVLLSSGEMFDPYPWAPAILPIQILRLGKLIILSVPGEFTTMAGRRLREAVKE 495
V+CQ PKP+LL SGE+ P+PW P I+ +QI+ +G L I ++PGE TTM+GRR REA+K+
Sbjct: 472 VECQKPKPILLHSGELTIPHPWQPDIVDVQIVTVGSLAIAAIPGELTTMSGRRFREAIKK 531
Query: 496 TLISNSNGEFNNETHVVIAGLTNTYSQYIATFEEYHQQRYEAASTLYGPHTLSAYIQEFN 555
+ VVIAGL+N Y+ YI T+EEY QRYEAAST+YGPHTLSAYIQ F
Sbjct: 532 EFALYGMKDMT----VVIAGLSNVYTHYITTYEEYQAQRYEAASTIYGPHTLSAYIQLFR 587
Query: 556 KLAQAMAKGDKI--YGNGTSPPDLLSVQKSFLLDPFGDTTPDGIKLGDIKEDIAFPGSGY 613
LA+A+A D + +G PP ++ S L+ D P G GD+ + P
Sbjct: 588 DLAKAIAT-DTVANMSSGPEPPFFKNLIAS-LIPNIADRAPIGKHFGDVLQ----PAKPE 641
Query: 614 FTKGDKPSATFWSANPR--YDLLTEGTYAVVERLQGE--RWISVQDDDDLSLFFRWKVDN 669
+ G+ F ANP+ + T T+ VE+ + W + +D F W
Sbjct: 642 YRVGEVVEVIFVGANPKNSAENQTHQTFLTVEKYEDSVADWQIMYNDASWETRFYWHKGI 701
Query: 670 TSFHGFAAIEWEIPTDAISGVYRLKHFGASKK-TIVSP--INYFTGASSAFAV 719
A I W IP A G+YR+++FG ++K ++ P I F G SS F V
Sbjct: 702 LGLSN-ATIYWHIPDTAYPGIYRIRYFGHNRKQELLKPAVILAFEGISSPFEV 753
>UniRef100_Q8BNP0 Mus musculus 4 days neonate male adipose cDNA, RIKEN full-length
enriched library, clone:B430217G19
product:N-acylsphingosine amidohydrolase 2, full insert
sequence [Mus musculus]
Length = 756
Score = 504 bits (1298), Expect = e-141
Identities = 294/713 (41%), Positives = 409/713 (57%), Gaps = 50/713 (7%)
Query: 23 YGEYLIGVGSYDMTGPAADVNMMGYANIEQNTAGIHFRLRARTFIVAENLQGPRFVFVNL 82
+ Y IGVG D TG +D+N+MGY QN G+ RL +R FI+A+ R FV++
Sbjct: 75 FSGYYIGVGRADCTGQVSDINLMGYGKNGQNARGLLTRLFSRAFILADPDGSNRMAFVSV 134
Query: 83 DAGMASQLLTIKLLERLKSRFGNLYTEENVAISGIHTHAGPGGYLQYVVYSVTSLGFVTQ 142
+ M SQ L +++L+RL+S++G+LY +NV +S IHTH+GP G+ QY +Y + S GF +
Sbjct: 135 ELCMISQRLRLEVLKRLESKYGSLYRRDNVILSAIHTHSGPAGFFQYTLYILASEGFSNR 194
Query: 143 SFDAIANAVEQSIIQAHNNLKPGSIFINTGDVKEASINRSPSAYLLNPAEERSRYPSNVD 202
+F I + + +SI AH NLKPG IFIN G+V INRSPS+YLLNP ER+RY SN D
Sbjct: 195 TFQYIVSGIMKSIDIAHTNLKPGKIFINKGNVANVQINRSPSSYLLNPQSERARYSSNTD 254
Query: 203 TQMTLLKFVDSASGKSKGSFSWFATHGTSMSNNNKLISGDNKDIGELVQIAQLIKATGGK 262
+M +LK VD +G+ G SWFA H SM+N+N ++ DN
Sbjct: 255 KEMLVLKLVD-LNGEDLGLISWFAIHPVSMNNSNHFVNSDNMGY---------------- 297
Query: 263 DCNEKSSQASKVRKNDGSL-----FVGAFCQSNVGDVSPNVLGAFCIDSGKPCDFNHSSC 317
++ + KN G L FV F SN+GDVSPN+LG C+++G+ CD + S+C
Sbjct: 298 -----AAYLFEQEKNKGYLPGQGPFVAGFASSNLGDVSPNILGPHCVNTGESCDNDKSTC 352
Query: 318 -NGNDLLCVGRGPGYPNEILSTKIIGERQFRSAVELFGSASEELTGKIDYRHVYLNFTNI 376
NG +C+ GPG + ST IIG ++ A EL+ SAS+E+TG + H ++N T++
Sbjct: 353 PNGGPSMCMASGPG-QDMFESTHIIGRIIYQKAKELYASASQEVTGPVLAAHQWVNMTDV 411
Query: 377 EVELDNKKVVKTCPAALGPGFAAGTTDGPGVFGFQQGDPEISPFWKNVRD-FLKEPSQYQ 435
V+L+ VKTC ALG FAAGT DG QG E PFW +RD L +PS+
Sbjct: 412 SVQLNATHTVKTCKPALGYSFAAGTIDGVSGLNITQGTTEGDPFWDTLRDQLLGKPSEEI 471
Query: 436 VDCQNPKPVLLSSGEMFDPYPWAPAILPIQILRLGKLIILSVPGEFTTMAGRRLREAVKE 495
V+CQ PKP+LL SGE+ P+PW P I+ +QI+ +G L I ++PGE TTM+GRR REA+K+
Sbjct: 472 VECQKPKPILLHSGELTIPHPWQPDIVDVQIVTVGSLAIAAIPGELTTMSGRRFREAIKK 531
Query: 496 TLISNSNGEFNNETHVVIAGLTNTYSQYIATFEEYHQQRYEAASTLYGPHTLSAYIQEFN 555
+ +VIAGL+N Y+ YI T+EEY QRYEAAST+YGPHTLSAYIQ F
Sbjct: 532 EFALYGMKDMT----IVIAGLSNVYTHYITTYEEYQAQRYEAASTIYGPHTLSAYIQLFR 587
Query: 556 KLAQAMAKGDKI--YGNGTSPPDLLSVQKSFLLDPFGDTTPDGIKLGDIKEDIAFPGSGY 613
LA+A+A D + +G PP ++ S L+ D P G GD+ + P
Sbjct: 588 DLAKAIAT-DTVANMSSGPEPPFFKNLIAS-LIPNIADRAPIGKHFGDVLQ----PAKPE 641
Query: 614 FTKGDKPSATFWSANPR--YDLLTEGTYAVVERLQGE--RWISVQDDDDLSLFFRWKVDN 669
+ G+ F ANP+ + T T+ VE+ + W + +D F W
Sbjct: 642 YRVGEVVEVIFVGANPKNSAENQTHQTFLTVEKYEDSVADWQIMYNDASWETRFYWHKGI 701
Query: 670 TSFHGFAAIEWEIPTDAISGVYRLKHFGASKK-TIVSP--INYFTGASSAFAV 719
A I W IP A G+YR+++FG ++K ++ P I F G SS F V
Sbjct: 702 LGLSN-ATIYWHIPDTAYPGIYRIRYFGHNRKQELLKPAVILAFEGISSPFEV 753
>UniRef100_Q91XT9 Ceramidase [Rattus norvegicus]
Length = 761
Score = 501 bits (1289), Expect = e-140
Identities = 292/713 (40%), Positives = 411/713 (56%), Gaps = 50/713 (7%)
Query: 23 YGEYLIGVGSYDMTGPAADVNMMGYANIEQNTAGIHFRLRARTFIVAENLQGPRFVFVNL 82
+ Y IGVG D TG +D+N+MGY QN G+ RL +R FI+A+ R FV++
Sbjct: 80 FSGYYIGVGRADCTGQVSDINLMGYGKNGQNAQGLLTRLFSRAFILADPDGSNRMAFVSV 139
Query: 83 DAGMASQLLTIKLLERLKSRFGNLYTEENVAISGIHTHAGPGGYLQYVVYSVTSLGFVTQ 142
+ M SQ L +++L+RL+S++G+LY +NV +S HTH+GP G+ QY +Y + S GF +
Sbjct: 140 ELCMISQRLRLEVLKRLQSKYGSLYRRDNVILSATHTHSGPAGFFQYTLYILASEGFSNR 199
Query: 143 SFDAIANAVEQSIIQAHNNLKPGSIFINTGDVKEASINRSPSAYLLNPAEERSRYPSNVD 202
+F I + + +SI AH NLKPG + IN G+V INRSPS+YL NP ER+RY S+ D
Sbjct: 200 TFQYIVSGIVKSIDIAHTNLKPGKVLINKGNVANVQINRSPSSYLQNPPSERARYSSDTD 259
Query: 203 TQMTLLKFVDSASGKSKGSFSWFATHGTSMSNNNKLISGDNKDIGELVQIAQLIKATGGK 262
+M +LK VD +G+ G SWFA H SM+N+N L++ DN
Sbjct: 260 KEMVVLKLVD-LNGEDLGLISWFAVHPVSMNNSNHLVNSDNMGY---------------- 302
Query: 263 DCNEKSSQASKVRKNDGSL-----FVGAFCQSNVGDVSPNVLGAFCIDSGKPCDFNHSSC 317
++ + KN G L FV F SN+GDVSPN+LG C+++G+ CD + S+C
Sbjct: 303 -----AAYLFEQEKNRGYLPGQGPFVAGFASSNLGDVSPNILGPHCVNTGESCDNDKSTC 357
Query: 318 -NGNDLLCVGRGPGYPNEILSTKIIGERQFRSAVELFGSASEELTGKIDYRHVYLNFTNI 376
+G +C+ GPG + ST IIG ++ A EL SAS+E+TG + H ++N T++
Sbjct: 358 PSGGPSMCMASGPG-QDMFESTHIIGRVIYQKAKELHASASQEVTGPVLTAHQWVNMTDV 416
Query: 377 EVELDNKKVVKTCPAALGPGFAAGTTDGPGVFGFQQGDPEISPFWKNVRD-FLKEPSQYQ 435
V+L+ VKTC AALG FAAGT DG QG E + FW +RD L +PS+
Sbjct: 417 SVQLNATHTVKTCKAALGYSFAAGTIDGVSGLNITQGTTEGNLFWDTLRDQLLGKPSEEI 476
Query: 436 VDCQNPKPVLLSSGEMFDPYPWAPAILPIQILRLGKLIILSVPGEFTTMAGRRLREAVKE 495
++CQ PKP+L+ +GE+ P+PW P I+ IQI+ LG L I ++PGEFTTM+GRRLREAVK+
Sbjct: 477 IECQKPKPILIHTGELTKPHPWQPDIVDIQIVTLGSLAIAAIPGEFTTMSGRRLREAVKK 536
Query: 496 TLISNSNGEFNNETHVVIAGLTNTYSQYIATFEEYHQQRYEAASTLYGPHTLSAYIQEFN 555
+ VVIAGL+N Y+ YI T+EEY QRYEAAST+YGPHTLSAYIQ F
Sbjct: 537 EFALYGMKDMT----VVIAGLSNVYTHYITTYEEYQAQRYEAASTIYGPHTLSAYIQLFR 592
Query: 556 KLAQAMAKGDKI--YGNGTSPPDLLSVQKSFLLDPFGDTTPDGIKLGDIKEDIAFPGSGY 613
LA+A+A D + +G PP ++ S L+ D P G + GD+ + P
Sbjct: 593 ALAKAIAT-DTVANMSSGPEPPFFKNLIGS-LIPNIADRAPIGKQFGDVLQ----PAKPE 646
Query: 614 FTKGDKPSATFWSANPR--YDLLTEGTYAVVERLQGE--RWISVQDDDDLSLFFRWKVDN 669
+ G+ F ANP+ + T T+ VE+ + W + +D F W
Sbjct: 647 YRVGEVVEVVFVGANPKNSAENQTHQTFLTVEKYEDSVANWQIMHNDASWETRFYWHKGV 706
Query: 670 TSFHGFAAIEWEIPTDAISGVYRLKHFGASKK-TIVSP--INYFTGASSAFAV 719
A I W IP A+ GVYR+++FG ++K ++ P I F G SS F +
Sbjct: 707 LGLSN-ATIHWHIPDTALPGVYRIRYFGHNRKQELLKPAVILAFEGISSPFEI 758
>UniRef100_UPI0000362C02 UPI0000362C02 UniRef100 entry
Length = 658
Score = 499 bits (1286), Expect = e-140
Identities = 282/691 (40%), Positives = 405/691 (57%), Gaps = 42/691 (6%)
Query: 38 PAADVNMMGYANIEQNTAGIHFRLRARTFIVAENLQGPRFVFVNLDAGMASQLLTIKLLE 97
P ++ MGYAN +Q AGIH RL +R FI+ + + R VFV D GM SQ L +++L
Sbjct: 1 PCYNLFQMGYANTKQTGAGIHTRLYSRAFIIDDGRK--RVVFVTADVGMVSQRLRLEVLN 58
Query: 98 RLKSRFGNLYTEENVAISGIHTHAGPGGYLQYVVYSVTSLGFVTQSFDAIANAVEQSIIQ 157
LK+++GNLY ++NV +SG HTH G GY QY ++ +TS G++ +S + N + +SI
Sbjct: 59 ALKTKYGNLYRQDNVVLSGTHTHCGLAGYFQYTLFMITSKGYIKESVQPLVNGIVKSIDI 118
Query: 158 AHNNLKPGSIFINTGDVKEASINRSPSAYLLNPAEERSRYPSNVDTQMTLLKFVDSASGK 217
AHNN KPG I+ + GD++ S+NRSP +Y+ NP EER+RY N D Q+ +LKF D G
Sbjct: 119 AHNNTKPGRIYRSRGDLEGNSVNRSPHSYMNNPEEERNRYKWNTDKQVLVLKFTD-LDGN 177
Query: 218 SKGSFSWFATHGTSMSNNNKLISGDNKDIGELVQIAQLIKATGGKDCNEKSSQASKVRKN 277
G SWFA H SM+ N+++S DN + E+ ++ +
Sbjct: 178 GIGMLSWFAVHAVSMNYTNRMVSSDNMGYASYLM--------------EQDKNPGELPGH 223
Query: 278 DGSLFVGAFCQSNVGDVSPNVLGAFCIDSGKPCDFNHSSCN-GNDLLCVGRGPGYPNEIL 336
G FV F SN+GDVSPN G C+++G PCD+ +SSC G +C GPG +
Sbjct: 224 GG--FVAGFSSSNLGDVSPNTKGPHCVNTGLPCDYLNSSCPVGGTKMCQSSGPG-EDMFE 280
Query: 337 STKIIGERQFRSAVELFGSASEELTGKIDYRHVYLNFTNIEVELDNKKVVKTCPAALGPG 396
ST+II ++ A EL+ +A EE+TG + H +++ TN+ +++++ V TC ALG
Sbjct: 281 STRIIAHNIYQKAKELYVNAKEEVTGFLHSAHQWVDMTNVTIQINSTHTVSTCKPALGHS 340
Query: 397 FAAGTTDGPGVFGFQQGDPEISPFWKNVRD-FLKEPSQYQVDCQNPKPVLLSSGEMFDPY 455
FAAGTTDG G F QG E PFW +RD + +PS +C +PKP+L S+GEM P
Sbjct: 341 FAAGTTDGGGDLNFTQGSVEGDPFWDGIRDVIVGKPSNETQECHHPKPILFSTGEMNWPL 400
Query: 456 PWAPAILPIQILRLGKLIILSVPGEFTTMAGRRLREAVKETLISNSNGEFNNETHVVIAG 515
PW P I+ +QI+ +G + +++VPGE TTM+GRRLRE+VK+ L S G F + VVIAG
Sbjct: 401 PWHPKIIDVQIITIGSVAVVAVPGEITTMSGRRLRESVKQEL--QSEGAF-RDVEVVIAG 457
Query: 516 LTNTYSQYIATFEEYHQQRYEAASTLYGPHTLSAYIQEFNKLAQAMAKGDKIYGNGTSPP 575
L+N Y+ YI TFEEY QRYE AST++GPHTLSAY+Q++ LA+A+A+ + G PP
Sbjct: 458 LSNVYTHYITTFEEYQVQRYEGASTIFGPHTLSAYLQKYRGLARAIAQAE--LPTGPQPP 515
Query: 576 DLLSVQKSF-LLDPFG-DTTPDGIKLGDIKEDIAFPGSGYFTKGDKPSATFWSANPRYD- 632
+K F L+ G D P+ GD+ + + +P + +GD S TF + NPR+
Sbjct: 516 ---FFKKLFNLMTAAGVDRKPENSSFGDVVQQV-YP---VYRQGDVVSITFIAGNPRHSG 568
Query: 633 LLTEGTYAVVERLQG--ERWISVQDDDDLSLFFRWKVDNTSFHGFAAIEWEIPTDAISGV 690
+ + T+ VE + W +V D F W + ++ + +EW IP A SG
Sbjct: 569 DIRDKTFVTVEIYDNRTDTWKTVHTDASWETRFHW-LKGSNRQSNSTVEWYIPPSAASGF 627
Query: 691 YRLKHFGASK--KTIVSPINYFTGASSAFAV 719
YR+KHFG K K + I + G S F+V
Sbjct: 628 YRIKHFGHFKQLKALRPVITPYEGTSDVFSV 658
>UniRef100_UPI0000362C01 UPI0000362C01 UniRef100 entry
Length = 615
Score = 479 bits (1233), Expect = e-133
Identities = 276/681 (40%), Positives = 390/681 (56%), Gaps = 72/681 (10%)
Query: 45 MGYANIEQNTAGIHFRLRARTFIVAENLQGPRFVFVNLDAGMASQLLTIKLLERLKSRFG 104
MGYAN +Q AGIH RL +R FI+ + + R VFV D GM SQ L +++L LK+++G
Sbjct: 1 MGYANTKQTGAGIHTRLYSRAFIIDDGRK--RVVFVTADVGMVSQRLRLEVLNALKTKYG 58
Query: 105 NLYTEENVAISGIHTHAGPGGYLQYVVYSVTSLGFVTQSFDAIANAVEQSIIQAHNNLKP 164
NLY ++NV +SG HTH G GY QY ++ +TS G++ +S + N + +SI AHNN KP
Sbjct: 59 NLYRQDNVVLSGTHTHCGLAGYFQYTLFMITSKGYIKESVQPLVNGIVKSIDIAHNNTKP 118
Query: 165 GSIFINTGDVKEASINRSPSAYLLNPAEERSRYPSNVDTQMTLLKFVDSASGKSKGSFSW 224
G I+ + GD++ S+NRSP +Y+ NP EER+RY N D Q+ +LKF D G G SW
Sbjct: 119 GRIYRSRGDLEGNSVNRSPHSYMNNPEEERNRYKWNTDKQVLVLKFTD-LDGNGIGMLSW 177
Query: 225 FATHGTSMSNNNKLISGDNKDIGELVQIAQLIKATGGKDCNEKSSQASKVRKNDGSLFVG 284
FA H SM+ N+++S DN + E+ ++ + G FV
Sbjct: 178 FAVHAVSMNYTNRMVSSDNMGYASYLM--------------EQDKNPGELPGHGG--FVA 221
Query: 285 AFCQSNVGDVSPNVLGAFCIDSGKPCDFNHSSCN-GNDLLCVGRGPGYPNEILSTKIIGE 343
F SN+GDVSPN G C+++G PCD+ +SSC G +C GPG + ST+II
Sbjct: 222 GFSSSNLGDVSPNTKGPHCVNTGLPCDYLNSSCPVGGTKMCQSSGPG-EDMFESTRIIAH 280
Query: 344 RQFRSAVELFGSASEELTGKIDYRHVYLNFTNIEVELDNKKVVKTCPAALGPGFAAGTTD 403
++ A EL+ +A EE+TG + H +++ TN+ +++++ V TC ALG FAAGTTD
Sbjct: 281 NIYQKAKELYVNAKEEVTGFLHSAHQWVDMTNVTIQINSTHTVSTCKPALGHSFAAGTTD 340
Query: 404 GPGVFGFQQGDPEISPFWKNVRD-FLKEPSQYQVDCQNPKPVLLSSGEMFDPYPWAPAIL 462
G G F QG E PFW +RD + +PS +C +PKP+L S+GEM P PW P I+
Sbjct: 341 GGGDLNFTQGSVEGDPFWDGIRDVIVGKPSNETQECHHPKPILFSTGEMNWPLPWHPKII 400
Query: 463 PIQILRLGKLIILSVPGEFTTMAGRRLREAVKETLISNSNGEFNNETHVVIAGLTNTYSQ 522
+QI+ +G + +++VPGE TTM+GRRLRE+VK+ L S G F + VVIAGL+N Y+
Sbjct: 401 DVQIITIGSVAVVAVPGEITTMSGRRLRESVKQEL--QSEGAF-RDVEVVIAGLSNVYTH 457
Query: 523 YIATFEEYHQQRYEAASTLYGPHTLSAYIQEFNKLAQAMAKGDKIYGNGTSPPDLLSVQK 582
YI TFEEY QRYE AST++GPHTLSAY+Q++ LA+A+A+ + G PP +K
Sbjct: 458 YITTFEEYQVQRYEGASTIFGPHTLSAYLQKYRGLARAIAQAE--LPTGPQPP---FFKK 512
Query: 583 SF-LLDPFG-DTTPDGIKLGDIKEDIAFPGSGYFTKGDKPSATFWSANPRYDLLTEGTYA 640
F L+ G D P+ GD+ + + +P + +GD S TF + NPR+ G
Sbjct: 513 LFNLMTAAGVDRKPENSSFGDVVQQV-YP---VYRQGDVVSITFIAGNPRH----SGDIV 564
Query: 641 VVERLQGERWISVQDDDDLSLFFRWKVDNTSFHGFAAIEWEIPTDAISGVYRLKHFGASK 700
+E+ + F EW IP A SG YR+KHFG K
Sbjct: 565 RIEK---------------KILF---------------EWYIPPSAASGFYRIKHFGHFK 594
Query: 701 --KTIVSPINYFTGASSAFAV 719
K + I + G S F+V
Sbjct: 595 QLKALRPVITPYEGTSDVFSV 615
>UniRef100_Q7YTD8 Neutral ceramidase [Drosophila melanogaster]
Length = 704
Score = 475 bits (1223), Expect = e-132
Identities = 280/708 (39%), Positives = 399/708 (55%), Gaps = 43/708 (6%)
Query: 26 YLIGVGSYDMTGPAADVNMMGYANIEQNTAGIHFRLRARTFIVAENLQGPRFVFVNLDAG 85
Y +GVG D+TGP ++N MGYANI+Q GIH R+ AR F+V E+ +G R FV+ DAG
Sbjct: 25 YKVGVGRADITGPPVEINFMGYANIKQVGRGIHTRVFARAFVV-EDEKGNRVAFVSADAG 83
Query: 86 MASQLLTIKLLERLKSRFGNLYTEENVAISGIHTHAGPGGYLQYVVYSVTSLGFVTQSFD 145
M L ++++RL++R+GN+Y +NVAISG HTH PGG+L +++Y ++ LGFV Q+F+
Sbjct: 84 MMGYGLKREVIKRLQARYGNIYHNDNVAISGTHTHGAPGGFLMHLLYDISILGFVPQTFE 143
Query: 146 AIANAVEQSIIQAHNNLKPGSIFINTGDVKEASINRSPSAYLLNPAEERSRYPSNVDTQM 205
+A + I +A +NL G I ++ V +INRSPS+YL NPAEER++Y + D +
Sbjct: 144 VMAQGLYLCIKRATDNLVDGRILLSKTTVLNVNINRSPSSYLRNPAEERAQYEHDTDKTL 203
Query: 206 TLLKFVDSASGKSKGSFSWFATHGTSMSNNNKLISGDNKDIGELVQIAQLIKATGGKDCN 265
T L+FVD G+F+W+A H TSM+N N+L++ DN L+
Sbjct: 204 TQLRFVD-LENNLLGAFNWYAVHATSMNNTNRLVTSDNVGYAALLL-------------- 248
Query: 266 EKSSQASKVRKNDGSLFVGAFCQSNVGDVSPNVLGAFCIDSGKPCDFNHSSCNGNDLLCV 325
EK +K+ FVGAFC SN+GDVSPN++G C SG CD S C + C
Sbjct: 249 EKEYNPNKMPGK--GKFVGAFCSSNLGDVSPNIMGPKCSISGNECDLLTSRCPTGEGDCF 306
Query: 326 GRGPGYPNEILSTKIIGERQFRSAVELFGSASE-----ELTGKIDYRHVYLNFTNIEVEL 380
GPG + ST+I+G+R +A+ L S+ E+TG + + H +++ N
Sbjct: 307 ASGPG-KDMFESTQILGQRLADAALGLLNEQSQESTALEVTGDVRFIHQFVDMPNYNGST 365
Query: 381 DN---KKV--VKTCPAALGPGFAAGTTDGPGVFGFQQGDPEISPFWKNVRDFLKEPSQYQ 435
N +KV V+ C A+G FAAGTTDGPG F F+QG +P W VRDF+ P+Q
Sbjct: 366 YNPLSRKVDKVRGCQPAMGYSFAAGTTDGPGAFSFEQGTTTDNPMWNFVRDFIAAPTQED 425
Query: 436 VDCQNPKPVLLSSGEMFDPYPWAPAILPIQILRLGKLIILSVPGEFTTMAGRRLREAVKE 495
+ C PKP+LL++G PY W P I+ Q+L++G +II +VP EFTTMAGRRLR ++
Sbjct: 426 IKCHEPKPILLATGRATFPYEWQPKIVSDQLLKIGDVIIAAVPCEFTTMAGRRLRNQIR- 484
Query: 496 TLISNSNGEFNNETHVVIAGLTNTYSQYIATFEEYHQQRYEAASTLYGPHTLSAYIQEFN 555
+ ++ +T V+IAGLTN Y+ Y T EEY QRYEAAST++GPHT S Y+ F
Sbjct: 485 ---AAASAVGGIDTEVIIAGLTNIYTSYTVTPEEYQAQRYEAASTIFGPHTHSIYMDVFE 541
Query: 556 KLAQAMAKGDKIYGNGTSPPDLLSVQKSFLLDPFGDTTPDGIKLGDIKEDIAFPGSGYFT 615
+L +AM + + + G SPP + V S D P G +K P Y
Sbjct: 542 RLTKAMMRNETV-DAGPSPPYMNDVMLSLNTGVLFDGHPINTDFGYVKSQ---PNKEYGI 597
Query: 616 KGDKPSATFWSANPRYDLLTEGTYAVVER-LQGERWISVQDDDDLSLFFRWKVDNTSFHG 674
+ T+ S NPR +L TE TY +ER + +RW D W NT G
Sbjct: 598 -NETVKVTYISGNPRNNLFTEKTYFTIERKINEDRWKVAYTDASWETKMIWHRTNTIL-G 655
Query: 675 FAAIE--WEIPTDAISGVYRLKHFGASKKTIVSPINYFTGASSAFAVQ 720
F+ ++ W+I + G YR++H G K + Y G + +F V+
Sbjct: 656 FSEMDIYWDISPQTLPGEYRIRHSGEYKYILGGKYPY-EGLTHSFTVK 702
>UniRef100_Q9VA70 CG1471-PA, isoform A [Drosophila melanogaster]
Length = 704
Score = 475 bits (1222), Expect = e-132
Identities = 279/708 (39%), Positives = 399/708 (55%), Gaps = 43/708 (6%)
Query: 26 YLIGVGSYDMTGPAADVNMMGYANIEQNTAGIHFRLRARTFIVAENLQGPRFVFVNLDAG 85
Y +GVG D+TGP ++N MGYANI+Q GIH R+ AR F+V E+ +G R FV+ DAG
Sbjct: 25 YKVGVGRADITGPPVEINFMGYANIKQVGRGIHTRVFARAFVV-EDEKGNRVAFVSADAG 83
Query: 86 MASQLLTIKLLERLKSRFGNLYTEENVAISGIHTHAGPGGYLQYVVYSVTSLGFVTQSFD 145
M L ++++RL++R+GN+Y +NVAISG HTH PGG+L +++Y ++ LGFV Q+F+
Sbjct: 84 MMGYGLKREVIKRLQARYGNIYHNDNVAISGTHTHGAPGGFLMHLLYDISILGFVPQTFE 143
Query: 146 AIANAVEQSIIQAHNNLKPGSIFINTGDVKEASINRSPSAYLLNPAEERSRYPSNVDTQM 205
+A + I +A +NL G I ++ V +INRSPS+YL NPAEER++Y + D +
Sbjct: 144 VMAQGLYLCIKRATDNLVDGRILLSKTTVLNVNINRSPSSYLRNPAEERAQYEHDTDKTL 203
Query: 206 TLLKFVDSASGKSKGSFSWFATHGTSMSNNNKLISGDNKDIGELVQIAQLIKATGGKDCN 265
T L+FVD G+F+W+A H TSM+N N+L++ DN L+
Sbjct: 204 TQLRFVD-LENNLLGAFNWYAVHATSMNNTNRLVTSDNVGYAALLL-------------- 248
Query: 266 EKSSQASKVRKNDGSLFVGAFCQSNVGDVSPNVLGAFCIDSGKPCDFNHSSCNGNDLLCV 325
EK +K+ FVGAFC SN+GDVSPN++G C SG CD S C + C
Sbjct: 249 EKEYNPNKMPGK--GKFVGAFCSSNLGDVSPNIMGPKCSISGNECDLLTSRCPTGEGDCF 306
Query: 326 GRGPGYPNEILSTKIIGERQFRSAVELFG-----SASEELTGKIDYRHVYLNFTNIEVEL 380
GPG + ST+I+G+R +A+ L S + E+TG + + H +++ N
Sbjct: 307 ASGPG-KDMFESTQILGQRLADAALGLLNEQSQESTAREVTGDVRFIHQFVDMPNYNGST 365
Query: 381 DN---KKV--VKTCPAALGPGFAAGTTDGPGVFGFQQGDPEISPFWKNVRDFLKEPSQYQ 435
N +KV ++ C A+G FAAGTTDGPG F F+QG +P W VRDF+ P+Q
Sbjct: 366 YNPLSRKVDKIRGCQPAMGYSFAAGTTDGPGAFSFEQGTTTDNPMWNFVRDFIAAPTQED 425
Query: 436 VDCQNPKPVLLSSGEMFDPYPWAPAILPIQILRLGKLIILSVPGEFTTMAGRRLREAVKE 495
+ C PKP+LL++G PY W P I+ Q+L++G +II +VP EFTTMAGRRLR ++
Sbjct: 426 IKCHEPKPILLATGRATFPYEWQPKIVSDQLLKIGDVIIAAVPCEFTTMAGRRLRNQIR- 484
Query: 496 TLISNSNGEFNNETHVVIAGLTNTYSQYIATFEEYHQQRYEAASTLYGPHTLSAYIQEFN 555
+ ++ +T V+IAGLTN Y+ Y T EEY QRYEAAST++GPHT S Y+ F
Sbjct: 485 ---AAASAVGGIDTEVIIAGLTNIYTSYTVTPEEYQAQRYEAASTIFGPHTHSIYMDVFE 541
Query: 556 KLAQAMAKGDKIYGNGTSPPDLLSVQKSFLLDPFGDTTPDGIKLGDIKEDIAFPGSGYFT 615
+L +AM + + + G SPP + V S D P G +K P Y
Sbjct: 542 RLTKAMMRNETV-DAGPSPPYMNDVMLSLNTGVLFDGHPINTDFGYVKSQ---PNKEYGI 597
Query: 616 KGDKPSATFWSANPRYDLLTEGTYAVVER-LQGERWISVQDDDDLSLFFRWKVDNTSFHG 674
+ T+ S NPR +L TE TY +ER + +RW D W NT G
Sbjct: 598 -NETVKVTYISGNPRNNLFTEKTYFTIERKINEDRWKVAYTDASWETKMVWHRTNTIL-G 655
Query: 675 FAAIE--WEIPTDAISGVYRLKHFGASKKTIVSPINYFTGASSAFAVQ 720
F+ ++ W+I + G YR++H G K + Y G + +F V+
Sbjct: 656 FSEMDIYWDISPQTLPGEYRIRHSGEYKYILGGKYPY-EGLTHSFTVK 702
>UniRef100_Q86NP1 SD07768p [Drosophila melanogaster]
Length = 704
Score = 475 bits (1222), Expect = e-132
Identities = 279/708 (39%), Positives = 399/708 (55%), Gaps = 43/708 (6%)
Query: 26 YLIGVGSYDMTGPAADVNMMGYANIEQNTAGIHFRLRARTFIVAENLQGPRFVFVNLDAG 85
Y +GVG D+TGP ++N MGYANI+Q GIH R+ AR F+V E+ +G R FV+ DAG
Sbjct: 25 YKVGVGRADITGPPVEINFMGYANIKQVGRGIHTRVFARAFVV-EDEKGNRVAFVSADAG 83
Query: 86 MASQLLTIKLLERLKSRFGNLYTEENVAISGIHTHAGPGGYLQYVVYSVTSLGFVTQSFD 145
M L ++++RL++R+GN+Y +NVAISG HTH PGG+L +++Y ++ LGFV Q+F+
Sbjct: 84 MMGYGLKREVIKRLQARYGNIYHNDNVAISGTHTHGAPGGFLMHLLYDISILGFVPQTFE 143
Query: 146 AIANAVEQSIIQAHNNLKPGSIFINTGDVKEASINRSPSAYLLNPAEERSRYPSNVDTQM 205
+A + I +A +NL G I ++ V +INRSPS+YL NPAEER++Y + D +
Sbjct: 144 VMAQGLYLCIKRATDNLVDGRILLSKTTVLNVNINRSPSSYLRNPAEERAQYEHDTDKTL 203
Query: 206 TLLKFVDSASGKSKGSFSWFATHGTSMSNNNKLISGDNKDIGELVQIAQLIKATGGKDCN 265
T L+FVD G+F+W+A H TSM+N N+L++ DN L+
Sbjct: 204 TQLRFVD-LENNLLGAFNWYAVHATSMNNTNRLVTSDNVGYAALLL-------------- 248
Query: 266 EKSSQASKVRKNDGSLFVGAFCQSNVGDVSPNVLGAFCIDSGKPCDFNHSSCNGNDLLCV 325
EK +K+ FVGAFC SN+GDVSPN++G C SG CD S C + C
Sbjct: 249 EKEYNPNKMPGK--GKFVGAFCSSNLGDVSPNIMGPKCSISGNECDLLTSRCPTGEGDCF 306
Query: 326 GRGPGYPNEILSTKIIGERQFRSAVELFG-----SASEELTGKIDYRHVYLNFTNIEVEL 380
GPG + ST+I+G+R +A+ L S + E+TG + + H +++ N
Sbjct: 307 ASGPG-KDMFESTQILGQRLADAALGLLNEQSQESTAREVTGDVRFIHQFVDMPNYNGST 365
Query: 381 DN---KKV--VKTCPAALGPGFAAGTTDGPGVFGFQQGDPEISPFWKNVRDFLKEPSQYQ 435
N +KV ++ C A+G FAAGTTDGPG F F+QG +P W VRDF+ P+Q
Sbjct: 366 YNPLSRKVDKIRGCQPAMGYSFAAGTTDGPGAFSFEQGTTTDNPMWNFVRDFIAAPTQED 425
Query: 436 VDCQNPKPVLLSSGEMFDPYPWAPAILPIQILRLGKLIILSVPGEFTTMAGRRLREAVKE 495
+ C PKP+LL++G PY W P I+ Q+L++G +II +VP EFTTMAGRRLR ++
Sbjct: 426 IKCHEPKPILLATGRATFPYEWQPKIVSDQLLKIGDVIIAAVPCEFTTMAGRRLRNQIR- 484
Query: 496 TLISNSNGEFNNETHVVIAGLTNTYSQYIATFEEYHQQRYEAASTLYGPHTLSAYIQEFN 555
+ ++ +T V+IAGLTN Y+ Y T EEY QRYEAAST++GPHT S Y+ F
Sbjct: 485 ---AAASAVGGIDTEVIIAGLTNIYTSYTVTPEEYQAQRYEAASTIFGPHTHSIYMDVFE 541
Query: 556 KLAQAMAKGDKIYGNGTSPPDLLSVQKSFLLDPFGDTTPDGIKLGDIKEDIAFPGSGYFT 615
+L +AM + + + G SPP + V S D P G +K P Y
Sbjct: 542 RLTKAMMRNETV-DAGPSPPYMNDVMLSLNTGVLFDGHPINTDFGYVKSQ---PNKEYGI 597
Query: 616 KGDKPSATFWSANPRYDLLTEGTYAVVER-LQGERWISVQDDDDLSLFFRWKVDNTSFHG 674
+ T+ S NPR +L TE TY +ER + +RW D W NT G
Sbjct: 598 -NETVKVTYISGNPRNNLFTEKTYFTIERKINEDRWKVAYTDASWETKMIWHRTNTIL-G 655
Query: 675 FAAIE--WEIPTDAISGVYRLKHFGASKKTIVSPINYFTGASSAFAVQ 720
F+ ++ W+I + G YR++H G K + Y G + +F V+
Sbjct: 656 FSEMDIYWDISPQTLPGEYRIRHSGEYKYILGGKYPY-EGLTHSFTVK 702
>UniRef100_UPI0000432379 UPI0000432379 UniRef100 entry
Length = 678
Score = 461 bits (1186), Expect = e-128
Identities = 270/710 (38%), Positives = 391/710 (55%), Gaps = 53/710 (7%)
Query: 26 YLIGVGSYDMTGPAADVNMMGYANIEQNTAGIHFRLRARTFIVAENLQGPRFVFVNLDAG 85
Y IGVG D TGP A++ MGYA I+Q +G+H R +R FI+ + ++ RFVFV++D+
Sbjct: 6 YTIGVGRADTTGPVAEIVFMGYAKIDQKGSGLHLRTFSRAFIIDDGVE--RFVFVSVDSA 63
Query: 86 MASQLLTIKLLERLKSRFGNLYTEENVAISGIHTHAGPGGYLQYVVYSVTSLGFVTQSFD 145
M + ++E L+ ++G+LYTE+NV IS H+H+ PGG++ ++++ +T+ GFV ++FD
Sbjct: 64 MIGNGIRQTVVENLQKQYGDLYTEKNVMISATHSHSTPGGFMLHMLFDLTTFGFVRETFD 123
Query: 146 AIANAVEQSIIQAHNNLKPGSIFINTGDVKEASINRSPSAYLLNPAEERSRYPSNVDTQM 205
A+ N + +SI +AHN + PG +FI G+V +INRSP AYL NP ER +Y NVD +
Sbjct: 124 AMVNGITKSIERAHNAMVPGRLFITHGEVHGVNINRSPFAYLNNPKVERDKYRDNVDKIL 183
Query: 206 TLLKFVDSASGKSKGSFSWFATHGTSMSNNNKLISGDNKDIGELVQIAQLIKATGGKDCN 265
T ++F + K G +WFA H TSM+N N L+S DN ++
Sbjct: 184 TQIQFYKNEDNKPLGVINWFAIHPTSMNNTNHLVSSDNIGYASVL--------------- 228
Query: 266 EKSSQASKVRKNDGSL----FVGAFCQSNVGDVSPNVLGAFCIDSGKPCDFNHSSCNGND 321
++ ND + FV AF SN+GDVSPN G C SG C + +C G
Sbjct: 229 -----FERIMNNDSLIGKGPFVAAFASSNLGDVSPNTRGPKCEFSGNNCSKQY-TCPGRK 282
Query: 322 LLCVGRGPGYPNEILSTKIIGERQFRSAVELFGSAS-EELTGKIDYRHVYLNFTNIEVEL 380
+C GPG N ST II R F+ + L+ +E+ G + H Y+N E
Sbjct: 283 EMCFASGPG-RNMFESTSIIANRMFKESWRLWQYGDVKEVIGPLRVVHRYVNMVEQTAEY 341
Query: 381 DNK-----KVVKTCPAALGPGFAAGTTDGPGVFGFQQGDPEISPFWKNVRDFLKEPSQYQ 435
N+ + V+ C A+G FAAGT DGPG F F+QG +P W VR+ L P+
Sbjct: 342 YNETTQRTETVRGCEPAMGYSFAAGTIDGPGSFSFRQGTTSANPMWNVVRNLLATPTNED 401
Query: 436 VDCQNPKPVLLSSGEMFDPYPWAPAILPIQILRLGKLIILSVPGEFTTMAGRRLREAVKE 495
+ C KP+LL++G M PY W P I+ Q+ +G ++I VPGEFTTM+GRRLREA+K
Sbjct: 402 IKCHGAKPILLATGHMTLPYEWQPKIVATQVALIGNVVIAGVPGEFTTMSGRRLREAIKT 461
Query: 496 TLISNSNGEFNNETHVVIAGLTNTYSQYIATFEEYHQQRYEAASTLYGPHTLSAYIQEFN 555
+ N ++ET V++AGL NTYS Y+ T EEY QRYE AST++GPHTL+ Y++++
Sbjct: 462 VM----NDASDDETSVIVAGLCNTYSDYVTTPEEYQIQRYEGASTIFGPHTLTIYLKQYQ 517
Query: 556 KLAQAMAKGDKIYGNGTSPPDL-LSVQKSFLLDPFGDTTPDGIKLGDI---KEDIAFPGS 611
+L A A K G P DL SF+ DT G GD + +A P
Sbjct: 518 ELVTA-AILKKDVEPGPEPVDLRKKTLVSFVTPVLYDTPIWGKNFGDCIKQPQKLAKP-- 574
Query: 612 GYFTKGDKPSATFWSANPRYDLLTEGTYAVVERL-QGERWISVQDDDDLSLFFRW-KVDN 669
GD +A F S +PR +L+TE ++ +ERL E W+ V D + F W ++
Sbjct: 575 -----GDIVTAVFVSGHPRNNLMTESSFLTIERLGVDEVWLPVATDANWETKFEWQRMSM 629
Query: 670 TSFHGFAAIEWEIPTDAISGVYRLKHFGASKKTIVSPINYFTGASSAFAV 719
I W++P D +G YR++H G + + Y+ G S+ F V
Sbjct: 630 VLGSSQVTITWQVPEDIKAGEYRIRHNGYYRYILGGIFPYY-GVSNHFQV 678
>UniRef100_UPI000045638E N-acylsphingosine amidohydrolase (Non-lysosomal ceramidase) 2C
[Homo sapiens]
Length = 612
Score = 456 bits (1172), Expect = e-126
Identities = 271/643 (42%), Positives = 369/643 (57%), Gaps = 50/643 (7%)
Query: 93 IKLLERLKSRFGNLYTEENVAISGIHTHAGPGGYLQYVVYSVTSLGFVTQSFDAIANAVE 152
+K+L RL+S++G+LY +NV +SG HTH+GP GY QY V+ + S GF Q+F + +
Sbjct: 1 LKVLNRLQSKYGSLYRRDNVILSGTHTHSGPAGYFQYTVFVIASEGFSNQTFQHMVTGIL 60
Query: 153 QSIIQAHNNLKPGSIFINTGDVKEASINRSPSAYLLNPAEERSRYPSNVDTQMTLLKFVD 212
+SI AH N+KPG IFIN G+V INRSP +YL NP ER+RY SN D +M +LK VD
Sbjct: 61 KSIDIAHTNMKPGKIFINKGNVDGVQINRSPYSYLQNPQSERARYSSNTDKEMIVLKMVD 120
Query: 213 SASGKSKGSFSWFATHGTSMSNNNKLISGDNKDIGELVQIAQLIKATGGKDCNEKSSQAS 272
+G G SWFA H SM+N+N L++ DN +G +S
Sbjct: 121 -LNGDDLGLISWFAIHPVSMNNSNHLVNSDN--VG-------------------YASYLL 158
Query: 273 KVRKNDGSL-----FVGAFCQSNVGDVSPNVLGAFCIDSGKPCDFNHSSCN-GNDLLCVG 326
+ KN G L FV AF SN+GDVSPN+LG CI++G+ CD +S+C G +C+
Sbjct: 159 EQEKNKGYLPGQGPFVAAFSSSNLGDVSPNILGPRCINTGESCDNANSTCPIGGPSMCIA 218
Query: 327 RGPGYPNEILSTKIIGERQFRSAVELFGSASEELTGKIDYRHVYLNFTNIEVELDNKKVV 386
+GPG + ST+IIG ++ A EL+ SAS+E+TG + H +++ T++ V L++
Sbjct: 219 KGPG-QDMFDSTQIIGRAMYQRAKELYASASQEVTGPLASAHQWVDMTDVTVWLNSTHAS 277
Query: 387 KTCPAALGPGFAAGTTDGPGVFGFQQGDPEISPFWKNVRD-FLKEPSQYQVDCQNPKPVL 445
KTC ALG FAAGT DG G F QG E PFW +RD L +PS+ +C PKP+L
Sbjct: 278 KTCKPALGYSFAAGTIDGVGGLNFTQGKTEGDPFWDTIRDQILGKPSEEIKECHKPKPIL 337
Query: 446 LSSGEMFDPYPWAPAILPIQILRLGKLIILSVPGEFTTMAGRRLREAVKETLISNSNGEF 505
L +GE+ P+PW P I+ +QI+ LG L I ++PGEFTTM+GRRLREAV+ S+
Sbjct: 338 LHTGELSKPHPWHPDIVDVQIITLGSLAITAIPGEFTTMSGRRLREAVQAEFASHG---M 394
Query: 506 NNETHVVIAGLTNTYSQYIATFEEYHQQRYEAASTLYGPHTLSAYIQEFNKLAQAMAKGD 565
N T VVI+GL N Y+ YI T+EEY QRYEAAST+YGPHTLSAYIQ F LA+A+A D
Sbjct: 395 QNMT-VVISGLCNVYTHYITTYEEYQAQRYEAASTIYGPHTLSAYIQLFRNLAKAIAT-D 452
Query: 566 KI--YGNGTSPPDLLSVQKSFLLDPFGDTTPDGIKLGDIKEDIAFPGSGYFTKGDKPSAT 623
+ G PP + L+ D P G GD+ + P + G+
Sbjct: 453 TVANLSRGPEPPFFKQLIVP-LIPSIVDRAPKGRTFGDVLQ----PAKPEYRVGEVAEVI 507
Query: 624 FWSANPRYDLLTEG--TYAVVERLQ--GERWISVQDDDDLSLFFRWKVDNTSFHGFAAIE 679
F ANP+ + + T+ VE+ + W V +D F W A +E
Sbjct: 508 FVGANPKNSVQNQNHQTFLTVEKYEATSTSWQIVCNDASWETRFYWHKGLLGLSN-ATVE 566
Query: 680 WEIPTDAISGVYRLKHFGASKK-TIVSP--INYFTGASSAFAV 719
W IP A G+YR+++FG ++K I+ P I F G S AF V
Sbjct: 567 WHIPDTAQPGIYRIRYFGHNRKQDILKPAVILSFEGTSPAFEV 609
Database: uniref100
Posted date: Jan 5, 2005 1:24 AM
Number of letters in database: 848,049,833
Number of sequences in database: 2,790,947
Lambda K H
0.317 0.136 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,290,514,142
Number of Sequences: 2790947
Number of extensions: 58863010
Number of successful extensions: 120545
Number of sequences better than 10.0: 70
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 120119
Number of HSP's gapped (non-prelim): 83
length of query: 720
length of database: 848,049,833
effective HSP length: 135
effective length of query: 585
effective length of database: 471,271,988
effective search space: 275694112980
effective search space used: 275694112980
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 79 (35.0 bits)
Medicago: description of AC146743.14