BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC146331.7 - phase: 0 
         (377 letters)

Database: uniref100 
           2,790,947 sequences; 848,049,833 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

UniRef100_P54967 Biotin synthase [Arabidopsis thaliana]               615  e-175
UniRef100_Q84WG4 Putative biotin synthase [Arabidopsis thaliana]      614  e-174
UniRef100_Q69U93 Putative biotin synthase [Oryza sativa]              600  e-170
UniRef100_UPI0000234873 UPI0000234873 UniRef100 entry                 406  e-112
UniRef100_Q7RXK2 Hypothetical protein [Neurospora crassa]             394  e-108
UniRef100_UPI000023DB78 UPI000023DB78 UniRef100 entry                 390  e-107
UniRef100_O59778 Biotin synthase [Schizosaccharomyces pombe]          387  e-106
UniRef100_UPI00003C10F7 UPI00003C10F7 UniRef100 entry                 385  e-105
UniRef100_UPI000042C201 UPI000042C201 UniRef100 entry                 382  e-105
UniRef100_Q6C903 Similar to sp|P32451 Saccharomyces cerevisiae Y...   376  e-103
UniRef100_Q8YVQ3 Biotin synthase [Anabaena sp.]                       371  e-101
UniRef100_Q9HF48 Biotin synthase long form [Pichia jadinii]           366  e-100
UniRef100_Q9HF47 Biotin synthase short form [Pichia jadinii]          366  e-100
UniRef100_Q6BX74 Similar to sp|P32451 Saccharomyces cerevisiae Y...   365  1e-99
UniRef100_Q6FAP9 Biotin synthetase [Acinetobacter sp.]                364  2e-99
UniRef100_P32451 Biotin synthase [Saccharomyces cerevisiae]           364  2e-99
UniRef100_Q9KSZ4 Biotin synthase [Vibrio cholerae]                    358  1e-97
UniRef100_Q6CXS8 Kluyveromyces lactis strain NRRL Y-1140 chromos...   358  2e-97
UniRef100_Q93GG2 Biotin synthase [Acinetobacter calcoaceticus]        357  3e-97
UniRef100_Q8PDF0 Biotin synthase [Xanthomonas campestris]             357  4e-97

>UniRef100_P54967 Biotin synthase [Arabidopsis thaliana]
          Length = 378

 Score =  615 bits (1587), Expect = e-175
 Identities = 297/378 (78%), Positives = 342/378 (89%), Gaps = 2/378 (0%)

Query: 1   MFWLRPILRSQSRSSI-WVLQHCNSFSTSSAAAIQAEKTIQNGPRNDWTKDEVKSIYDSP 59
           M  +R + RSQ R S+   LQ  + +S+ SAA+ +AE+TI+ GPRNDW++DE+KS+YDSP
Sbjct: 1   MMLVRSVFRSQLRPSVSGGLQSASCYSSLSAASAEAERTIREGPRNDWSRDEIKSVYDSP 60

Query: 60  ILDLLFHGAQVHRHAHNFREVQQCTLLSVKTGGCSEDCSYCPQSSRYDTGLKGQKLLNKD 119
           +LDLLFHGAQVHRH HNFREVQQCTLLS+KTGGCSEDCSYCPQSSRY TG+K Q+L++KD
Sbjct: 61  LLDLLFHGAQVHRHVHNFREVQQCTLLSIKTGGCSEDCSYCPQSSRYSTGVKAQRLMSKD 120

Query: 120 AVLQAAVKAKEAGSTRFCMGAAWRDTIGRKTNFNQILEYVKEIKGMGMEVCCTLGMLDKD 179
           AV+ AA KAKEAGSTRFCMGAAWRDTIGRKTNF+QILEY+KEI+GMGMEVCCTLGM++K 
Sbjct: 121 AVIDAAKKAKEAGSTRFCMGAAWRDTIGRKTNFSQILEYIKEIRGMGMEVCCTLGMIEKQ 180

Query: 180 QAGELKKAGLTAYNHNLDTSREYYPNIITTRTYDERLKTLEFVRDAGINVCSGGIIGLGE 239
           QA ELKKAGLTAYNHNLDTSREYYPN+ITTR+YD+RL+TL  VRDAGINVCSGGIIGLGE
Sbjct: 181 QALELKKAGLTAYNHNLDTSREYYPNVITTRSYDDRLETLSHVRDAGINVCSGGIIGLGE 240

Query: 240 AEDDRVGLLHTLSTLPTHPESVPINALIAVKGTPLQDQKPVEIWEMIRMIATARITMPKA 299
           AE+DR+GLLHTL+TLP+HPESVPINAL+AVKGTPL+DQKPVEIWEMIRMI TARI MPKA
Sbjct: 241 AEEDRIGLLHTLATLPSHPESVPINALLAVKGTPLEDQKPVEIWEMIRMIGTARIVMPKA 300

Query: 300 MVRLSAGRVRFSVPEQALCFLAGANSIFAGEKLLTTANNDFDADQLMFKVLGLLPKAPSL 359
           MVRLSAGRVRFS+ EQALCFLAGANSIF GEKLLTT NNDFDADQLMFK LGL+PK PS 
Sbjct: 301 MVRLSAGRVRFSMSEQALCFLAGANSIFTGEKLLTTPNNDFDADQLMFKTLGLIPKPPSF 360

Query: 360 DDDETNEAENYKEAASSS 377
            +D+ +E+EN ++ AS+S
Sbjct: 361 SEDD-SESENCEKVASAS 377


>UniRef100_Q84WG4 Putative biotin synthase [Arabidopsis thaliana]
          Length = 378

 Score =  614 bits (1583), Expect = e-174
 Identities = 296/378 (78%), Positives = 342/378 (90%), Gaps = 2/378 (0%)

Query: 1   MFWLRPILRSQSRSSI-WVLQHCNSFSTSSAAAIQAEKTIQNGPRNDWTKDEVKSIYDSP 59
           M  +R + RSQ R S+   LQ  + +S+ SAA+ +AE+TI+ GPRNDW++DE+KS+YDSP
Sbjct: 1   MMLVRSVFRSQLRPSVSGGLQSASCYSSLSAASAEAERTIREGPRNDWSRDEIKSVYDSP 60

Query: 60  ILDLLFHGAQVHRHAHNFREVQQCTLLSVKTGGCSEDCSYCPQSSRYDTGLKGQKLLNKD 119
           +LDLLFHGAQVHRH HNFREVQQCTLLS+KTGGCSEDCSYCPQSSRY TG+K Q+L++KD
Sbjct: 61  LLDLLFHGAQVHRHVHNFREVQQCTLLSIKTGGCSEDCSYCPQSSRYSTGVKAQRLMSKD 120

Query: 120 AVLQAAVKAKEAGSTRFCMGAAWRDTIGRKTNFNQILEYVKEIKGMGMEVCCTLGMLDKD 179
           AV+ AA KAKEAGSTRFCMGAAWRDTIGRKTNF+QILEY+KEI+GMGMEVCCTLGM+++ 
Sbjct: 121 AVIDAAKKAKEAGSTRFCMGAAWRDTIGRKTNFSQILEYIKEIRGMGMEVCCTLGMIEEQ 180

Query: 180 QAGELKKAGLTAYNHNLDTSREYYPNIITTRTYDERLKTLEFVRDAGINVCSGGIIGLGE 239
           QA ELKKAGLTAYNHNLDTSREYYPN+ITTR+YD+RL+TL  VRDAGINVCSGGIIGLGE
Sbjct: 181 QALELKKAGLTAYNHNLDTSREYYPNVITTRSYDDRLETLSHVRDAGINVCSGGIIGLGE 240

Query: 240 AEDDRVGLLHTLSTLPTHPESVPINALIAVKGTPLQDQKPVEIWEMIRMIATARITMPKA 299
           AE+DR+GLLHTL+TLP+HPESVPINAL+AVKGTPL+DQKPVEIWEMIRMI TARI MPKA
Sbjct: 241 AEEDRIGLLHTLATLPSHPESVPINALLAVKGTPLEDQKPVEIWEMIRMIGTARIVMPKA 300

Query: 300 MVRLSAGRVRFSVPEQALCFLAGANSIFAGEKLLTTANNDFDADQLMFKVLGLLPKAPSL 359
           MVRLSAGRVRFS+ EQALCFLAGANSIF GEKLLTT NNDFDADQLMFK LGL+PK PS 
Sbjct: 301 MVRLSAGRVRFSMSEQALCFLAGANSIFTGEKLLTTPNNDFDADQLMFKTLGLIPKPPSF 360

Query: 360 DDDETNEAENYKEAASSS 377
            +D+ +E+EN ++ AS+S
Sbjct: 361 SEDD-SESENCEKVASAS 377


>UniRef100_Q69U93 Putative biotin synthase [Oryza sativa]
          Length = 381

 Score =  600 bits (1547), Expect = e-170
 Identities = 295/379 (77%), Positives = 335/379 (87%), Gaps = 4/379 (1%)

Query: 1   MFWLRPILRSQSRSSIWVLQHCNSFSTSSA---AAIQAEKTIQNGPRNDWTKDEVKSIYD 57
           M   R +LRS+ R         ++ + SSA   AA +AE+ +++GPRNDW++ E++++YD
Sbjct: 2   MLLARAVLRSRLRCPPLSAAAASTAAFSSAPSPAAAEAERAVRDGPRNDWSRPEIQAVYD 61

Query: 58  SPILDLLFHGAQVHRHAHNFREVQQCTLLSVKTGGCSEDCSYCPQSSRYDTGLKGQKLLN 117
           SP+LDLLFHGAQVHR  H FREVQQCTLLS+KTGGCSEDCSYCPQSSRY TGLK QKL+N
Sbjct: 62  SPLLDLLFHGAQVHRSVHKFREVQQCTLLSIKTGGCSEDCSYCPQSSRYSTGLKAQKLMN 121

Query: 118 KDAVLQAAVKAKEAGSTRFCMGAAWRDTIGRKTNFNQILEYVKEIKGMGMEVCCTLGMLD 177
           KDAVL+AA KAKEAGSTRFCMGAAWR+TIGRKTNFNQILEYVK+I+GMGMEVCCTLGML+
Sbjct: 122 KDAVLEAAKKAKEAGSTRFCMGAAWRETIGRKTNFNQILEYVKDIRGMGMEVCCTLGMLE 181

Query: 178 KDQAGELKKAGLTAYNHNLDTSREYYPNIITTRTYDERLKTLEFVRDAGINVCSGGIIGL 237
           K QA ELKKAGLTAYNHNLDTSREYYPNII+TR+YD+RL+TLE VR+AGI++CSGGIIGL
Sbjct: 182 KQQAEELKKAGLTAYNHNLDTSREYYPNIISTRSYDDRLQTLEHVREAGISICSGGIIGL 241

Query: 238 GEAEDDRVGLLHTLSTLPTHPESVPINALIAVKGTPLQDQKPVEIWEMIRMIATARITMP 297
           GEAE+DRVGLLHTL+TLP HPESVPINAL+AVKGTPLQDQKPVEIWEMIRMIATARI MP
Sbjct: 242 GEAEEDRVGLLHTLATLPAHPESVPINALVAVKGTPLQDQKPVEIWEMIRMIATARIVMP 301

Query: 298 KAMVRLSAGRVRFSVPEQALCFLAGANSIFAGEKLLTTANNDFDADQLMFKVLGLLPKAP 357
           KAMVRLSAGRVRFS+PEQALCFLAGANSIFAGEKLLTT NNDFDADQ MFK+LGL+PKAP
Sbjct: 302 KAMVRLSAGRVRFSMPEQALCFLAGANSIFAGEKLLTTTNNDFDADQAMFKILGLIPKAP 361

Query: 358 SLDDD-ETNEAENYKEAAS 375
           S  D+    + E  +EAAS
Sbjct: 362 SFGDEAPAADTERCEEAAS 380


>UniRef100_UPI0000234873 UPI0000234873 UniRef100 entry
          Length = 393

 Score =  406 bits (1043), Expect = e-112
 Identities = 198/344 (57%), Positives = 252/344 (72%), Gaps = 3/344 (0%)

Query: 24  SFSTSSAAAIQAEKTIQNGPRNDWTKDEVKSIYDSPILDLLFHGAQVHRHAHNFREVQQC 83
           SF++    A+Q E      PR +WT+DEV+ IY++P+  L +  A VHR  H+   +Q C
Sbjct: 28  SFASRIPPALQ-EAVAATAPRTNWTRDEVQQIYETPLNQLTYAAAAVHRRFHDPSAIQMC 86

Query: 84  TLLSVKTGGCSEDCSYCPQSSRYDTGLKGQKLLNKDAVLQAAVKAKEAGSTRFCMGAAWR 143
           TL+++KTGGCSEDCSYC QSSRY TGLK  K+   D VL+ A  AK  GSTRFCMGAAWR
Sbjct: 87  TLMNIKTGGCSEDCSYCAQSSRYSTGLKATKMSPVDDVLEKARIAKANGSTRFCMGAAWR 146

Query: 144 DTIGRKTNFNQILEYVKEIKGMGMEVCCTLGMLDKDQAGELKKAGLTAYNHNLDTSREYY 203
           D  GRKT+   + + V  ++ MGMEVC TLGM+D DQA ELK AGLTAYNHNLDTSRE+Y
Sbjct: 147 DMRGRKTSLKNVKQMVSGVREMGMEVCVTLGMIDADQAKELKDAGLTAYNHNLDTSREFY 206

Query: 204 PNIITTRTYDERLKTLEFVRDAGINVCSGGIIGLGEAEDDRVGLLHTLSTLPTHPESVPI 263
           P IITTR+YDERLKTL  VRDAGINVCSGGI+GLGEA+ DR+GL+HT+S+LP+HPES P+
Sbjct: 207 PTIITTRSYDERLKTLSHVRDAGINVCSGGILGLGEADSDRIGLIHTVSSLPSHPESFPV 266

Query: 264 NALIAVKGTPLQDQKPVEIWEMIRMIATARITMPKAMVRLSAGRVRFSVPEQALCFLAGA 323
           NAL+ +KGTPL D+K +   +++R +ATARI +P  +VRL+AGR+  +  +Q  CF+AGA
Sbjct: 267 NALVPIKGTPLGDRKMISFDKLLRTVATARIVLPATIVRLAAGRISLTEEQQVACFMAGA 326

Query: 324 NSIFAGEKLLTTANNDFDADQLMFKVLGLLPKAPSLDDDETNEA 367
           N++F GEK+LTT  N +D D+ MF   G  P      + ETN A
Sbjct: 327 NAVFTGEKMLTTDCNGWDEDRAMFDRWGFYPMRSF--EKETNAA 368


>UniRef100_Q7RXK2 Hypothetical protein [Neurospora crassa]
          Length = 439

 Score =  394 bits (1013), Expect = e-108
 Identities = 203/397 (51%), Positives = 266/397 (66%), Gaps = 33/397 (8%)

Query: 8   LRSQSRSSIWVLQHCNSFSTSSAAAIQAEKTIQ------------------NGPRNDWTK 49
           LR QSR S    +  +S + S  A I A    Q                  + PRNDWTK
Sbjct: 28  LRFQSRLSHAQFRSLSSAAGSQVANIPATNKYQKLDSFAGRNSLLQATIAADAPRNDWTK 87

Query: 50  DEVKSIYDSPILDLLFHGAQVHRHAHNFREVQQCTLLSVKTGGCSEDCSYCPQSSRYDTG 109
           +E++ IY +P+++L++  + +HR   +   VQ CTL+++KTGGCSEDCSYC QSSRY TG
Sbjct: 88  EEIREIYQTPLMELVYSASTLHRRFFDPASVQLCTLMNIKTGGCSEDCSYCAQSSRYKTG 147

Query: 110 LKGQKLLNKDAVLQAAVKAKEAGSTRFCMGAAWRDTIGRKTNFNQILEYVKEIKGMGMEV 169
           +K  K+ + D VLQAA  AKE GSTRFCMGAAWRD  GRKTN   I   V  ++ +GME 
Sbjct: 148 VKATKISSVDEVLQAAKIAKENGSTRFCMGAAWRDMRGRKTNLKNIKAMVSGVRELGMEA 207

Query: 170 CCTLGMLDKDQAGELKKAGLTAYNHNLDTSREYYPNIITTRTYDERLKTLEFVRDAGINV 229
           C TLGM+D+ QA EL+ AGLTAYNHN+DTSREYYPN+ITTRTYDERLKT+  VR AGI+V
Sbjct: 208 CVTLGMIDESQAAELRDAGLTAYNHNVDTSREYYPNVITTRTYDERLKTINNVRQAGIHV 267

Query: 230 CSGGIIGLGEAEDDRVGLLHTLSTLPTHPESVPINALIAVKGTPLQD-----------QK 278
           CSGGI+GLGE + DRV  L+T++T+ +HPES PINAL+ +KGTPL D           + 
Sbjct: 268 CSGGILGLGEDDTDRVSFLYTVATMESHPESFPINALVPIKGTPLGDASAAKSETGEPES 327

Query: 279 PVEIWEMIRMIATARITMPKAMVRLSAGRVRFSVPEQALCFLAGANSIFAGEKLLTTANN 338
            V   + +RM+ATAR+ +P +++RL+AGR+  +  EQALCF+AGAN+IF GEK+LTT  +
Sbjct: 328 TVTFHDTVRMVATARLVLPGSVIRLAAGRINLTESEQALCFMAGANAIFTGEKMLTTPCS 387

Query: 339 DFDADQLMFKVLGLLPKAPSLDDDETNEAENYKEAAS 375
            +D D+ MF   GL P  P    DE + +E  + A +
Sbjct: 388 GWDEDKAMFDRWGLRPMLP----DELHGSEKRQHAGT 420


>UniRef100_UPI000023DB78 UPI000023DB78 UniRef100 entry
          Length = 436

 Score =  390 bits (1003), Expect = e-107
 Identities = 196/339 (57%), Positives = 244/339 (71%), Gaps = 28/339 (8%)

Query: 44  RNDWTKDEVKSIYDSPILDLLFHG--------------------------AQVHRHAHNF 77
           R+DWTKDE+ +IY  P+L+L +                            + VHR  HN 
Sbjct: 81  RHDWTKDEIAAIYYQPVLELAYQATADLIPDSNHSIAEQYHRLPRLTLNQSTVHRRWHNP 140

Query: 78  REVQQCTLLSVKTGGCSEDCSYCPQSSRYD--TGLKGQKLLNKDAVLQAAVKAKEAGSTR 135
            EVQ CTL+++KTGGC+EDCSYC QS+RY   TG+  +++ + ++VL AA  AKE GSTR
Sbjct: 141 SEVQLCTLMNIKTGGCTEDCSYCAQSTRYQEGTGVPAKRVESVESVLAAARIAKEKGSTR 200

Query: 136 FCMGAAWRDTIGRKTNFNQILEYVKEIKGMGMEVCCTLGMLDKDQAGELKKAGLTAYNHN 195
           FCMGAAWRD  GRK +   I   V+ +KGMGMEVC TLGM+D +QA ELK AGLTAYNHN
Sbjct: 201 FCMGAAWRDMRGRKNSLKNIKAMVEGVKGMGMEVCVTLGMIDAEQAKELKAAGLTAYNHN 260

Query: 196 LDTSREYYPNIITTRTYDERLKTLEFVRDAGINVCSGGIIGLGEAEDDRVGLLHTLSTLP 255
           +DTSRE+YPN+ITTR+YDERL+TL  VRDAGINVCSGGI+GLGE+ +DRVGLLHT+STLP
Sbjct: 261 VDTSREFYPNVITTRSYDERLQTLSHVRDAGINVCSGGILGLGESSEDRVGLLHTVSTLP 320

Query: 256 THPESVPINALIAVKGTPLQDQKPVEIWEMIRMIATARITMPKAMVRLSAGRVRFSVPEQ 315
           +HPES P+NAL+ +KGTPL D+  VE   M+R IATARI MP  ++R++AGR   S  +Q
Sbjct: 321 SHPESFPVNALVPIKGTPLGDRPMVEFTSMLRTIATARIIMPSTIIRIAAGRKTMSEEKQ 380

Query: 316 ALCFLAGANSIFAGEKLLTTANNDFDADQLMFKVLGLLP 354
           ALCF+AGAN+IF GEK+LTT  N +D D  MF   GL P
Sbjct: 381 ALCFMAGANAIFTGEKMLTTECNGWDEDAAMFGRWGLEP 419


>UniRef100_O59778 Biotin synthase [Schizosaccharomyces pombe]
          Length = 363

 Score =  387 bits (993), Expect = e-106
 Identities = 185/311 (59%), Positives = 238/311 (76%), Gaps = 2/311 (0%)

Query: 44  RNDWTKDEVKSIYDSPILDLLFHGAQVHRHAHNFREVQQCTLLSVKTGGCSEDCSYCPQS 103
           RN+WT++E++ IYD+P++DL+F  A +HR  H+ ++VQQCTLLS+KTGGC+EDC YC QS
Sbjct: 20  RNNWTREEIQKIYDTPLIDLIFRAASIHRKFHDPKKVQQCTLLSIKTGGCTEDCKYCAQS 79

Query: 104 SRYDTGLKGQKLLNKDAVLQAAVKAKEAGSTRFCMGAAWRDTIGRKTNFNQILEYVKEIK 163
           SRY+TG+K  KL+  D VL+ A  AK  GSTRFCMG+AWRD  GR   F  ILE +KE++
Sbjct: 80  SRYNTGVKATKLMKIDEVLEKAKIAKAKGSTRFCMGSAWRDLNGRNRTFKNILEIIKEVR 139

Query: 164 GMGMEVCCTLGMLDKDQAGELKKAGLTAYNHNLDTSREYYPNIITTRTYDERLKTLEFVR 223
            M MEVC TLGML++ QA ELK AGLTAYNHNLDTSREYY  II+TRTYDERL T++ +R
Sbjct: 140 SMDMEVCVTLGMLNEQQAKELKDAGLTAYNHNLDTSREYYSKIISTRTYDERLNTIDNLR 199

Query: 224 DAGINVCSGGIIGLGEAEDDRVGLLHTLSTLPTHPESVPINALIAVKGTPLQD--QKPVE 281
            AG+ VCSGGI+GLGE + DRVGL+H+L+T+PTHPESVP N L+ + GTP+ D  ++ + 
Sbjct: 200 KAGLKVCSGGILGLGEKKHDRVGLIHSLATMPTHPESVPFNLLVPIPGTPVGDAVKERLP 259

Query: 282 IWEMIRMIATARITMPKAMVRLSAGRVRFSVPEQALCFLAGANSIFAGEKLLTTANNDFD 341
           I   +R IATARI MPK ++R +AGR   S  EQAL F+AGAN++F GEK+LTT    +D
Sbjct: 260 IHPFLRSIATARICMPKTIIRFAAGRNTCSESEQALAFMAGANAVFTGEKMLTTPAVSWD 319

Query: 342 ADQLMFKVLGL 352
           +D  +F   GL
Sbjct: 320 SDSQLFYNWGL 330


>UniRef100_UPI00003C10F7 UPI00003C10F7 UniRef100 entry
          Length = 436

 Score =  385 bits (989), Expect = e-105
 Identities = 186/331 (56%), Positives = 245/331 (73%), Gaps = 1/331 (0%)

Query: 23  NSFSTSSAAAIQAEKTIQNGP-RNDWTKDEVKSIYDSPILDLLFHGAQVHRHAHNFREVQ 81
           +S S +SA+          G  R++W++ EV+ IYDSP+L+L+F  A VHR  H    VQ
Sbjct: 61  SSLSVASASTAATSLPSNEGAIRHNWSRKEVQRIYDSPLLELVFRSANVHRMHHPVNRVQ 120

Query: 82  QCTLLSVKTGGCSEDCSYCPQSSRYDTGLKGQKLLNKDAVLQAAVKAKEAGSTRFCMGAA 141
            CTL+++K GGCSEDC YC QSS+Y+T     KL + + VL  A KAK  GSTRFCMGAA
Sbjct: 121 LCTLMNIKEGGCSEDCGYCSQSSKYETPSNASKLEDLETVLTEARKAKANGSTRFCMGAA 180

Query: 142 WRDTIGRKTNFNQILEYVKEIKGMGMEVCCTLGMLDKDQAGELKKAGLTAYNHNLDTSRE 201
           WR+  GRK  FN+IL+ V+EI+GMGMEVC TLGML  +QA +LK+AGLTAYNHNLDTSRE
Sbjct: 181 WREVGGRKRGFNRILDMVREIRGMGMEVCTTLGMLTPEQAKQLKEAGLTAYNHNLDTSRE 240

Query: 202 YYPNIITTRTYDERLKTLEFVRDAGINVCSGGIIGLGEAEDDRVGLLHTLSTLPTHPESV 261
           YY  ++TTR+YD+R+ T+  VR+AGI+VCSGGI+GLGE  +DRVGL+  +STLP HPES 
Sbjct: 241 YYGKVVTTRSYDDRIGTIANVREAGISVCSGGILGLGEEHEDRVGLIWEMSTLPEHPESF 300

Query: 262 PINALIAVKGTPLQDQKPVEIWEMIRMIATARITMPKAMVRLSAGRVRFSVPEQALCFLA 321
           P+NAL+A+ GTP++  KP+   EM+R +ATARI +P +++RL+AGR  F+  EQA+ FLA
Sbjct: 301 PVNALVAIPGTPMEQNKPITFQEMLRTVATARIVLPGSIIRLAAGRHLFTESEQAMAFLA 360

Query: 322 GANSIFAGEKLLTTANNDFDADQLMFKVLGL 352
           GAN+IF GE++LTT  + +D D+ M    GL
Sbjct: 361 GANAIFTGERMLTTPTSSWDEDKAMLGRWGL 391


>UniRef100_UPI000042C201 UPI000042C201 UniRef100 entry
          Length = 388

 Score =  382 bits (982), Expect = e-105
 Identities = 186/367 (50%), Positives = 265/367 (71%), Gaps = 5/367 (1%)

Query: 4   LRPILRSQSRSSI--WVLQHCNSFSTSSAAAIQAEKT--IQNGPRNDWTKDEVKSIYDSP 59
           LRP+LRS + ++     +     F   S +  Q+EK   +    R+DW + E++ ++D+P
Sbjct: 7   LRPVLRSTAPTASRGHAVAVDAPFLPPSPSVQQSEKRRYVDGDVRHDWRRSEIQKVFDAP 66

Query: 60  ILDLLFHGAQVHRHAHNFREVQQCTLLSVKTGGCSEDCSYCPQSSRYDTGLKGQKLLNKD 119
           ++++++  A VHR   +   +Q CTL+++KTGGC+E+C YC QSS Y T  K  +L++ +
Sbjct: 67  LMEIIYRAATVHRLHQDASRIQLCTLMNIKTGGCTENCKYCSQSSSYKTPTKASRLVSIE 126

Query: 120 AVLQAAVKAKEAGSTRFCMGAAWRDTIGRKTNFNQILEYVKEIKGMGMEVCCTLGMLDKD 179
            VL+AA +AK  GSTRFCMGAAWRD  GRK+ F +ILE VKE++GMGMEVC TLGML  +
Sbjct: 127 PVLEAARQAKANGSTRFCMGAAWRDLAGRKSGFEKILEMVKEVRGMGMEVCTTLGMLSPE 186

Query: 180 QAGELKKAGLTAYNHNLDTSREYYPNIITTRTYDERLKTLEFVRDAGINVCSGGIIGLGE 239
           QA  LK+AGL+AYNHNLDTSRE+YP ++T+R+YD+RL T+  VR+AGI+VCSGGI+GLGE
Sbjct: 187 QAIRLKEAGLSAYNHNLDTSREFYPEVVTSRSYDDRLSTIAAVREAGISVCSGGILGLGE 246

Query: 240 AEDDRVGLLHTLSTLPTHPESVPINALIAVKGTPLQDQKPVEIWEMIRMIATARITMPKA 299
            ++DRVGL+H +S +P HPES P+N L+ + GTPL+  +PV++  ++R IATARI +PK 
Sbjct: 247 RDEDRVGLIHEVSRMPEHPESFPVNTLVPIPGTPLEGNEPVKVHTVLRTIATARIVLPKT 306

Query: 300 MVRLSAGRVRFSVPEQALCFLAGANSIFAGEKLLTTANNDFDADQLMFKVLGLLPKAPSL 359
           ++RL+AGR  FS  EQA+ F+AGAN+IF GEK+LTT  + +D D+ M    GL  +  S 
Sbjct: 307 IIRLAAGRHEFSETEQAMAFMAGANAIFTGEKMLTTPCSGWDEDKAMLDRWGLRGQR-SF 365

Query: 360 DDDETNE 366
           +D E+ E
Sbjct: 366 EDKESLE 372


>UniRef100_Q6C903 Similar to sp|P32451 Saccharomyces cerevisiae YGR286c BIO2 biotin
           synthetase [Yarrowia lipolytica]
          Length = 384

 Score =  376 bits (965), Expect = e-103
 Identities = 180/335 (53%), Positives = 240/335 (70%), Gaps = 5/335 (1%)

Query: 25  FSTSSAAAIQAEKTIQNGPRNDWTKDEVKSIYDSPILDLLFHGAQVHRHAHNFREVQQCT 84
           F  + A+    + T  +  R +WT+DEV  IY+ P++DL+F  A VHR  HN  EVQ CT
Sbjct: 14  FVRNLASHASFQPTTSSAIRTNWTRDEVSKIYNMPLMDLVFKAATVHRQHHNPAEVQLCT 73

Query: 85  LLSVKTGGCSEDCSYCPQSSRYDTGLKGQKLLNKDAVLQAAVKAKEAGSTRFCMGAAWRD 144
           L ++K+GGC+EDC YC QSSRY TG++ +K +    V+ AA +AK  GSTRFCMGAAWRD
Sbjct: 74  LYNIKSGGCTEDCKYCAQSSRYTTGVEAEKAVKPAEVIAAAKEAKANGSTRFCMGAAWRD 133

Query: 145 TIGRKTNFNQILEYVKEIKGMGMEVCCTLGMLDKDQAGELKKAGLTAYNHNLDTSREYYP 204
             GRK     + E +  +  +GME C TLGM+DK QA EL++AGLTAYNHN+DTSRE+YP
Sbjct: 134 MKGRKNALKNVKEMIGAVHELGMESCVTLGMVDKAQAEELRRAGLTAYNHNIDTSREHYP 193

Query: 205 NIITTRTYDERLKTLEFVRDAGINVCSGGIIGLGEAEDDRVGLLHTLSTLPTHPESVPIN 264
            +ITTRT+DERL+T+E VR+AG++VCSGGI+GLGE  DD VG L  L+T+P+HPES+PIN
Sbjct: 194 KVITTRTFDERLQTIENVREAGVSVCSGGILGLGETADDHVGFLWALATMPSHPESLPIN 253

Query: 265 ALIAVKGTPLQD-----QKPVEIWEMIRMIATARITMPKAMVRLSAGRVRFSVPEQALCF 319
            L+ +KGTPL D     +K +    ++R +ATAR+ MP + +RL+AGR     PEQA+CF
Sbjct: 254 RLVPIKGTPLGDDPAMKEKQLTYDTVVRTVATARVVMPGSKIRLAAGRYTMKEPEQAMCF 313

Query: 320 LAGANSIFAGEKLLTTANNDFDADQLMFKVLGLLP 354
           +AGAN+IF G+K+LTT  N +D D+ M +  GL P
Sbjct: 314 MAGANAIFTGKKMLTTMCNGWDEDKAMLEKWGLKP 348


>UniRef100_Q8YVQ3 Biotin synthase [Anabaena sp.]
          Length = 335

 Score =  371 bits (953), Expect = e-101
 Identities = 183/319 (57%), Positives = 237/319 (73%), Gaps = 5/319 (1%)

Query: 44  RNDWTKDEVKSIYDSPILDLLFHGAQVHRHAHNFREVQQCTLLSVKTGGCSEDCSYCPQS 103
           R DW K E++++YD+P+L+L++  A VHR  HN +++Q C L+S+KTG C EDCSYC QS
Sbjct: 7   RYDWHKAEIRAVYDTPLLELIYQAASVHRQFHNPKQIQVCKLISIKTGACPEDCSYCAQS 66

Query: 104 SRYDTGLKGQKLLNKDAVLQAAVKAKEAGSTRFCMGAAWRDTIGRKTNFNQILEYVKEIK 163
           SRY T +K Q LL+K  V++ A  AK+ G +R CMGAAWR+ +   + F+++LE VK++ 
Sbjct: 67  SRYQTEVKPQALLDKQTVVEIAQNAKQKGVSRVCMGAAWRE-VRDNSQFDRVLEMVKDVT 125

Query: 164 GMGMEVCCTLGMLDKDQAGELKKAGLTAYNHNLDTSREYYPNIITTRTYDERLKTLEFVR 223
            MG+EVCCTLGML  +QA +L+ AGL AYNHNLDTS +YY  IITTRTY +RL T+E VR
Sbjct: 126 DMGLEVCCTLGMLTSEQAKKLETAGLYAYNHNLDTSSDYYSTIITTRTYGDRLNTIENVR 185

Query: 224 DAGINVCSGGIIGLGEAEDDRVGLLHTLSTLPTHPESVPINALIAVKGTPLQDQKPVEIW 283
              + VCSGGI+GLGE+ DDRV +L TL+TL  HPESVPIN L  V+GTPL+DQ  V +W
Sbjct: 186 QTNVTVCSGGILGLGESIDDRVAMLQTLATLNPHPESVPINILSQVEGTPLEDQPDVPVW 245

Query: 284 EMIRMIATARITMPKAMVRLSAGRVRFSVPEQALCFLAGANSIFAGE--KLL--TTANND 339
           +++RMIATARI MP + VRLSAGR R S  EQA CF+AGANSIF+ +  K+L  TT   D
Sbjct: 246 DVVRMIATARIVMPTSDVRLSAGRARLSQVEQAFCFMAGANSIFSSDDNKMLTVTTPCPD 305

Query: 340 FDADQLMFKVLGLLPKAPS 358
           +DADQ M  +LGL  + PS
Sbjct: 306 YDADQEMLNLLGLEMRPPS 324


>UniRef100_Q9HF48 Biotin synthase long form [Pichia jadinii]
          Length = 395

 Score =  366 bits (940), Expect = e-100
 Identities = 167/315 (53%), Positives = 235/315 (74%), Gaps = 3/315 (0%)

Query: 43  PRNDWTKDEVKSIYDSPILDLLFHGAQVHRHAHNFREVQQCTLLSVKTGGCSEDCSYCPQ 102
           P N WTK+E+K+IYD+P++DL+ +    HR      EVQ CTL+++KTGGC+EDC YC Q
Sbjct: 66  PVNTWTKEEIKAIYDTPLMDLMHYAQVQHRRFQQPSEVQLCTLMNIKTGGCTEDCKYCAQ 125

Query: 103 SSRYDTGLKGQKLLNKDAVLQAAVKAKEAGSTRFCMGAAWRDTIGRKTNFNQILEYVKEI 162
           S RY+TG+K ++++  D V++AA +AK  GSTRFCMGAAWR+  GRK+N  +I E +  +
Sbjct: 126 SQRYNTGVKAERIIQVDEVIEAAKEAKANGSTRFCMGAAWREMKGRKSNLKKIKEMITAV 185

Query: 163 KGMGMEVCCTLGMLDKDQAGELKKAGLTAYNHNLDTSREYYPNIITTRTYDERLKTLEFV 222
             +GME C TLGM+DKDQA ELK AGLTAYNHN+DT +E+YP +I+TR++D+RLKT + V
Sbjct: 186 HDLGMESCVTLGMVDKDQATELKSAGLTAYNHNIDTYKEHYPKVISTRSFDDRLKTFKNV 245

Query: 223 RDAGINVCSGGIIGLGEAEDDRVGLLHTLSTLPTHPESVPINALIAVKGTPLQDQ---KP 279
           + +G+  C+GGI+GLGE ++DRV  L+TL+T+  HPES+PIN L+ +KGTP+ ++   K 
Sbjct: 246 QGSGLKACTGGILGLGETQEDRVSFLYTLATMDQHPESLPINRLVPIKGTPMYEEVKNKQ 305

Query: 280 VEIWEMIRMIATARITMPKAMVRLSAGRVRFSVPEQALCFLAGANSIFAGEKLLTTANND 339
           VE+ E++R IATAR+ MP +++RL+AGR      EQ +CF+AG N+IF G+K+LTT  N 
Sbjct: 306 VEVDEIVRTIATARLVMPTSIIRLAAGRYTMKEAEQVMCFMAGCNAIFTGKKMLTTMCNG 365

Query: 340 FDADQLMFKVLGLLP 354
           +D D+ M    GL P
Sbjct: 366 WDEDKAMLAKWGLKP 380


>UniRef100_Q9HF47 Biotin synthase short form [Pichia jadinii]
          Length = 352

 Score =  366 bits (940), Expect = e-100
 Identities = 167/315 (53%), Positives = 235/315 (74%), Gaps = 3/315 (0%)

Query: 43  PRNDWTKDEVKSIYDSPILDLLFHGAQVHRHAHNFREVQQCTLLSVKTGGCSEDCSYCPQ 102
           P N WTK+E+K+IYD+P++DL+ +    HR      EVQ CTL+++KTGGC+EDC YC Q
Sbjct: 23  PVNTWTKEEIKAIYDTPLMDLMHYAQVQHRRFQQPSEVQLCTLMNIKTGGCTEDCKYCAQ 82

Query: 103 SSRYDTGLKGQKLLNKDAVLQAAVKAKEAGSTRFCMGAAWRDTIGRKTNFNQILEYVKEI 162
           S RY+TG+K ++++  D V++AA +AK  GSTRFCMGAAWR+  GRK+N  +I E +  +
Sbjct: 83  SQRYNTGVKAERIIQVDEVIEAAKEAKANGSTRFCMGAAWREMKGRKSNLKKIKEMITAV 142

Query: 163 KGMGMEVCCTLGMLDKDQAGELKKAGLTAYNHNLDTSREYYPNIITTRTYDERLKTLEFV 222
             +GME C TLGM+DKDQA ELK AGLTAYNHN+DT +E+YP +I+TR++D+RLKT + V
Sbjct: 143 HDLGMESCVTLGMVDKDQATELKSAGLTAYNHNIDTYKEHYPKVISTRSFDDRLKTFKNV 202

Query: 223 RDAGINVCSGGIIGLGEAEDDRVGLLHTLSTLPTHPESVPINALIAVKGTPLQDQ---KP 279
           + +G+  C+GGI+GLGE ++DRV  L+TL+T+  HPES+PIN L+ +KGTP+ ++   K 
Sbjct: 203 QGSGLKACTGGILGLGETQEDRVSFLYTLATMDQHPESLPINRLVPIKGTPMYEEVKNKQ 262

Query: 280 VEIWEMIRMIATARITMPKAMVRLSAGRVRFSVPEQALCFLAGANSIFAGEKLLTTANND 339
           VE+ E++R IATAR+ MP +++RL+AGR      EQ +CF+AG N+IF G+K+LTT  N 
Sbjct: 263 VEVDEIVRTIATARLVMPTSIIRLAAGRYTMKEAEQVMCFMAGCNAIFTGKKMLTTMCNG 322

Query: 340 FDADQLMFKVLGLLP 354
           +D D+ M    GL P
Sbjct: 323 WDEDKAMLAKWGLKP 337


>UniRef100_Q6BX74 Similar to sp|P32451 Saccharomyces cerevisiae YGR286c BIO2 biotin
           synthetase [Debaryomyces hansenii]
          Length = 426

 Score =  365 bits (937), Expect = 1e-99
 Identities = 172/322 (53%), Positives = 237/322 (73%), Gaps = 10/322 (3%)

Query: 43  PRNDWTKDEVKSIYDSPILDLLFHGAQVHRHAHNFREVQQCTLLSVKTGGCSEDCSYCPQ 102
           P N WTKD+++ IY++P+++L+F     HR  HN +EVQ CTLLS+KTGGC+EDC YC Q
Sbjct: 69  PLNSWTKDQIREIYNTPLMELVFQSQIQHRKYHNPQEVQLCTLLSIKTGGCTEDCKYCAQ 128

Query: 103 SSRYDTGLKGQKLLNKDAVLQAAVKAKEAGSTRFCMGAAWRDTIGRKTNFNQILEYVKEI 162
           S+RYDTG K +++++ D V++AA  AK  GSTRFCMGAAWRD  GRK+   +I + V +I
Sbjct: 129 STRYDTGTKAERMISVDEVMKAARTAKANGSTRFCMGAAWRDMTGRKSGLKRISQMVTQI 188

Query: 163 -KGMGMEVCCTLGMLDKDQAGELKKAGLTAYNHNLDTSREYYPNIITTRTYDERLKTLEF 221
            + +GME C TLGM+DK QA +L  AGLTAYNHN+DTSRE+YP +I+TR+YDERL+T+  
Sbjct: 189 NQELGMETCVTLGMVDKKQAADLADAGLTAYNHNIDTSREHYPKVISTRSYDERLQTIRN 248

Query: 222 VRDAGINVCSGGIIGLGEAEDDRVGLLHTLSTLPTHPESVPINALIAVKGTPLQDQ---- 277
           V+DAGI  C+GGI+GLGE E+D +G L+TLST+  HPES+PIN L+ +KGTP++ +    
Sbjct: 249 VQDAGIKACTGGILGLGETEEDHIGFLYTLSTMEKHPESLPINRLVPIKGTPMEKEISSL 308

Query: 278 -----KPVEIWEMIRMIATARITMPKAMVRLSAGRVRFSVPEQALCFLAGANSIFAGEKL 332
                + ++   +++ IATAR+ MP++++RL+AGR      EQ LCF++G N+IF GEK+
Sbjct: 309 PRESGRRLKFEHILKTIATARLIMPESIIRLAAGRYTMKEHEQFLCFMSGCNAIFTGEKM 368

Query: 333 LTTANNDFDADQLMFKVLGLLP 354
           LTT  N +D D  M K  GL P
Sbjct: 369 LTTMCNGWDEDIQMLKKWGLRP 390


>UniRef100_Q6FAP9 Biotin synthetase [Acinetobacter sp.]
          Length = 337

 Score =  364 bits (935), Expect = 2e-99
 Identities = 178/327 (54%), Positives = 236/327 (71%), Gaps = 2/327 (0%)

Query: 33  IQAEKTIQNGPRNDWTKDEVKSIYDSPILDLLFHGAQVHRHAHNFREVQQCTLLSVKTGG 92
           +Q+  T+    RNDWT+DE++++YD P LDL+F   QVHR   +   +Q  TLLS+KTG 
Sbjct: 1   MQSSWTMTMTLRNDWTRDEIQALYDQPFLDLVFQAQQVHREHFSANTIQVSTLLSIKTGK 60

Query: 93  CSEDCSYCPQSSRYDTGLKGQKLLNKDAVLQAAVKAKEAGSTRFCMGAAWRDTIGRKTNF 152
           C EDC YC QS+ YD+ L+ +K +  D V+  A  AK++GS+RFCMGAAWR+   R   +
Sbjct: 61  CPEDCKYCSQSAHYDSKLEAEKRIAVDKVISEAKAAKDSGSSRFCMGAAWRNPHERDMPY 120

Query: 153 NQILEYVKEIKGMGMEVCCTLGMLDKDQAGELKKAGLTAYNHNLDTSREYYPNIITTRTY 212
             +LE V+E+K +G+E C TLGML++ QA  L  AGL  YNHNLDTSREYY NII+TRT+
Sbjct: 121 --VLEMVREVKALGLETCMTLGMLNQSQAERLSDAGLDYYNHNLDTSREYYNNIISTRTF 178

Query: 213 DERLKTLEFVRDAGINVCSGGIIGLGEAEDDRVGLLHTLSTLPTHPESVPINALIAVKGT 272
           D+RL TL+ VR AG+ VCSGGI+GLGE + DR+GLLH L+TLP HPESVPIN L+ ++GT
Sbjct: 179 DDRLNTLDHVRSAGMKVCSGGIVGLGEQKQDRIGLLHELATLPIHPESVPINMLVPIEGT 238

Query: 273 PLQDQKPVEIWEMIRMIATARITMPKAMVRLSAGRVRFSVPEQALCFLAGANSIFAGEKL 332
           PL D + +++ E IR IA ARI MP + +RLSAGR   S  +QAL F+AGANS+F+G+KL
Sbjct: 239 PLADVEKLDVTEWIRTIAVARIIMPYSYIRLSAGRESLSDSDQALAFMAGANSLFSGDKL 298

Query: 333 LTTANNDFDADQLMFKVLGLLPKAPSL 359
           LTT N     DQ++F  LGL+ + P +
Sbjct: 299 LTTPNAGEGKDQVLFAKLGLVAEKPKV 325


>UniRef100_P32451 Biotin synthase [Saccharomyces cerevisiae]
          Length = 375

 Score =  364 bits (935), Expect = 2e-99
 Identities = 178/338 (52%), Positives = 246/338 (72%), Gaps = 9/338 (2%)

Query: 24  SFSTSSAAAIQAEKTIQNGPRNDWTKDEVKSIYDSPILDLLFHGAQV-HRHAHNFREVQQ 82
           S   S+  A+Q   ++   P + WTK ++K IY +P+L+L  H AQ+ HR  H+  +VQ 
Sbjct: 31  SSEASTLGALQYALSLDE-PSHSWTKSQLKEIYHTPLLELT-HAAQLQHRKWHDPTKVQL 88

Query: 83  CTLLSVKTGGCSEDCSYCPQSSRYDTGLKGQKLLNKDAVLQAAVKAKEAGSTRFCMGAAW 142
           CTL+++K+GGCSEDC YC QSSR DTGLK +K++  D V++ A +AK  GSTRFC+GAAW
Sbjct: 89  CTLMNIKSGGCSEDCKYCAQSSRNDTGLKAEKMVKVDEVIKEAEEAKRNGSTRFCLGAAW 148

Query: 143 RDTIGRKTNFNQILEYVKEIKGMGMEVCCTLGMLDKDQAGELKKAGLTAYNHNLDTSREY 202
           RD  GRK+   +I E V ++  MG+E C TLGM+D+DQA +LK AGLTAYNHN+DTSRE+
Sbjct: 149 RDMKGRKSAMKRIQEMVTKVNDMGLETCVTLGMVDQDQAKQLKDAGLTAYNHNIDTSREH 208

Query: 203 YPNIITTRTYDERLKTLEFVRDAGINVCSGGIIGLGEAEDDRVGLLHTLSTLPTHPESVP 262
           Y  +ITTRTYD+RL+T++ V+++GI  C+GGI+GLGE+EDD +G ++TLS +  HPES+P
Sbjct: 209 YSKVITTRTYDDRLQTIKNVQESGIKACTGGILGLGESEDDHIGFIYTLSNMSPHPESLP 268

Query: 263 INALIAVKGTPLQDQ------KPVEIWEMIRMIATARITMPKAMVRLSAGRVRFSVPEQA 316
           IN L+A+KGTP+ ++      K ++  E++R IATARI MPKA++RL+AGR      EQ 
Sbjct: 269 INRLVAIKGTPMAEELADPKSKKLQFDEILRTIATARIVMPKAIIRLAAGRYTMKETEQF 328

Query: 317 LCFLAGANSIFAGEKLLTTANNDFDADQLMFKVLGLLP 354
           +CF+AG NSIF G+K+LTT  N +D D+ M    GL P
Sbjct: 329 VCFMAGCNSIFTGKKMLTTMCNGWDEDKAMLAKWGLQP 366


>UniRef100_Q9KSZ4 Biotin synthase [Vibrio cholerae]
          Length = 350

 Score =  358 bits (920), Expect = 1e-97
 Identities = 182/325 (56%), Positives = 230/325 (70%), Gaps = 2/325 (0%)

Query: 44  RNDWTKDEVKSIYDSPILDLLFHGAQVHRHAHNFREVQQCTLLSVKTGGCSEDCSYCPQS 103
           R++WT  EVK++ D P +DLLF   QVHR  H    VQ  TLLS+KTG C EDC YCPQS
Sbjct: 4   RHNWTVAEVKALLDKPFMDLLFEAQQVHRLHHPHNHVQVSTLLSIKTGACPEDCKYCPQS 63

Query: 104 SRYDTGLKGQKLLNKDAVLQAAVKAKEAGSTRFCMGAAWRDTIGRKTNFNQILEYVKEIK 163
           + Y T +  ++L+  + VL AA KAK +GSTRFCMGAAW++   ++ +   + E ++ +K
Sbjct: 64  AHYRTDVDKERLMEVERVLDAAQKAKNSGSTRFCMGAAWKNP--KERDMPLLKEMIRGVK 121

Query: 164 GMGMEVCCTLGMLDKDQAGELKKAGLTAYNHNLDTSREYYPNIITTRTYDERLKTLEFVR 223
            MG+E C TLGML  DQA +L +AGL  YNHNLDTS E+Y NIITTRTY +RL TL  VR
Sbjct: 122 DMGLETCMTLGMLTPDQAQQLAQAGLDYYNHNLDTSPEFYGNIITTRTYQDRLDTLSHVR 181

Query: 224 DAGINVCSGGIIGLGEAEDDRVGLLHTLSTLPTHPESVPINALIAVKGTPLQDQKPVEIW 283
           DAG+ +CSGGIIG+GE+ +DR GLL  L+ LPTHPESVPIN L+ VKGTPL+    VE +
Sbjct: 182 DAGMKICSGGIIGMGESTNDRAGLLVELANLPTHPESVPINMLVKVKGTPLEQVDDVEPF 241

Query: 284 EMIRMIATARITMPKAMVRLSAGRVRFSVPEQALCFLAGANSIFAGEKLLTTANNDFDAD 343
           + +R+IA ARI MPK+ VRLSAGR + +   QALCF+AGANSIF G KLLTT N   D+D
Sbjct: 242 DFVRLIAVARIMMPKSAVRLSAGREKMNEQMQALCFMAGANSIFYGCKLLTTPNPAEDSD 301

Query: 344 QLMFKVLGLLPKAPSLDDDETNEAE 368
            L+FK LG+  +  +   DE  E E
Sbjct: 302 MLLFKKLGINREQVAQKPDEITENE 326


>UniRef100_Q6CXS8 Kluyveromyces lactis strain NRRL Y-1140 chromosome A of strain NRRL
           Y- 1140 of Kluyveromyces lactis [Kluyveromyces lactis]
          Length = 379

 Score =  358 bits (918), Expect = 2e-97
 Identities = 167/320 (52%), Positives = 235/320 (73%), Gaps = 6/320 (1%)

Query: 41  NGPRNDWTKDEVKSIYDSPILDLLFHGAQVHRHAHNFREVQQCTLLSVKTGGCSEDCSYC 100
           N P++ WTK+++  IY +P+++L+      HR  H+  +VQ CTL+++K GGCSEDC YC
Sbjct: 39  NEPQHVWTKEQLAEIYHTPLMELMHQAQLQHRKWHDPTKVQLCTLMNIKAGGCSEDCKYC 98

Query: 101 PQSSRYDTGLKGQKLLNKDAVLQAAVKAKEAGSTRFCMGAAWRDTIGRKTNFNQILEYVK 160
            QSSRYDTGLK +K+++ + V++ A  AKE GSTRFC+GAAWR+  GRK+   +I E + 
Sbjct: 99  AQSSRYDTGLKAEKMISVEEVIKEAQIAKENGSTRFCLGAAWREMRGRKSALKRIGEMIG 158

Query: 161 EIKGMGMEVCCTLGMLDKDQAGELKKAGLTAYNHNLDTSREYYPNIITTRTYDERLKTLE 220
           +I  MGME C TLGM+D+ QA +LK AGLTAYNHN+DTSRE+YP +I+TR+YD+RL+T++
Sbjct: 159 KINEMGMESCVTLGMVDETQAKQLKDAGLTAYNHNIDTSREHYPKVISTRSYDDRLQTIK 218

Query: 221 FVRDAGINVCSGGIIGLGEAEDDRVGLLHTLSTLPTHPESVPINALIAVKGTPLQDQ--- 277
            V+DAGI  C+GGI+GLGE EDD +G +HTL+ +  HPES+PIN L+++KGTP+ ++   
Sbjct: 219 NVQDAGIKACTGGILGLGETEDDHIGFVHTLANMSPHPESLPINRLVSIKGTPMHEELKK 278

Query: 278 ---KPVEIWEMIRMIATARITMPKAMVRLSAGRVRFSVPEQALCFLAGANSIFAGEKLLT 334
              K +E  E++R +A ARI MP+A++RL+AGR      EQ LCF+AG N+IF G+K+LT
Sbjct: 279 VSSKKLEFDEILRTVALARIVMPQAIIRLAAGRYTMKETEQFLCFMAGCNAIFVGKKMLT 338

Query: 335 TANNDFDADQLMFKVLGLLP 354
           T    +D D+ M    GL P
Sbjct: 339 TMCTGWDEDKAMLSKWGLQP 358


>UniRef100_Q93GG2 Biotin synthase [Acinetobacter calcoaceticus]
          Length = 329

 Score =  357 bits (916), Expect = 3e-97
 Identities = 173/309 (55%), Positives = 226/309 (72%), Gaps = 2/309 (0%)

Query: 44  RNDWTKDEVKSIYDSPILDLLFHGAQVHRHAHNFREVQQCTLLSVKTGGCSEDCSYCPQS 103
           RNDWT+DE++++YD P LDL+F    VHR       +Q  TLLS+KTG C EDC YC QS
Sbjct: 4   RNDWTRDEIQALYDQPFLDLVFEAQSVHRQHFQANTIQVSTLLSIKTGKCPEDCKYCSQS 63

Query: 104 SRYDTGLKGQKLLNKDAVLQAAVKAKEAGSTRFCMGAAWRDTIGRKTNFNQILEYVKEIK 163
           + YD+ L+ +K +  D V+  A  AKE+GS+RFCMGAAWR+   R   +  +LE V+E+K
Sbjct: 64  AHYDSKLEAEKRIAVDKVISEAQAAKESGSSRFCMGAAWRNPHERDMPY--VLEMVREVK 121

Query: 164 GMGMEVCCTLGMLDKDQAGELKKAGLTAYNHNLDTSREYYPNIITTRTYDERLKTLEFVR 223
            +G+E C TLGML++ QA  LK AGL  YNHNLDTSREYY +II+TRT+D+RL TL+ VR
Sbjct: 122 ALGLETCMTLGMLNQSQAERLKDAGLDYYNHNLDTSREYYSHIISTRTFDDRLNTLDHVR 181

Query: 224 DAGINVCSGGIIGLGEAEDDRVGLLHTLSTLPTHPESVPINALIAVKGTPLQDQKPVEIW 283
            AG+ VCSGGI+GLGE+ +DR+GLL  L+T+P HPESVPIN L+ ++GTPL + + +++ 
Sbjct: 182 HAGMKVCSGGIVGLGESRNDRIGLLQELATMPVHPESVPINMLVPIEGTPLAEVEKLDVT 241

Query: 284 EMIRMIATARITMPKAMVRLSAGRVRFSVPEQALCFLAGANSIFAGEKLLTTANNDFDAD 343
           E IR IA ARI MP + +RLSAGR   S  +QAL F+AGANS+F+GEKLLTT N     D
Sbjct: 242 EWIRTIAVARIIMPHSYIRLSAGRESLSDSDQALAFMAGANSLFSGEKLLTTPNAGEGKD 301

Query: 344 QLMFKVLGL 352
           Q++F  LGL
Sbjct: 302 QILFAKLGL 310


>UniRef100_Q8PDF0 Biotin synthase [Xanthomonas campestris]
          Length = 344

 Score =  357 bits (915), Expect = 4e-97
 Identities = 179/320 (55%), Positives = 226/320 (69%), Gaps = 2/320 (0%)

Query: 44  RNDWTKDEVKSIYDSPILDLLFHGAQVHRHAHNFREVQQCTLLSVKTGGCSEDCSYCPQS 103
           R+DW + E+ +++  P  +LL   A VHR   +  EVQ  TLLSVKTGGC EDC+YCPQ+
Sbjct: 6   RHDWDRKELHALFALPFPELLHRAASVHRAHFDPAEVQVSTLLSVKTGGCPEDCAYCPQA 65

Query: 104 SRYDTGLKGQKLLNKDAVLQAAVKAKEAGSTRFCMGAAWRDTIGRKTNFNQILEYVKEIK 163
            RYDTG+  QKL++ + V+  A +AK AG++RFCMGAAWR    R  +  ++   ++E+K
Sbjct: 66  QRYDTGVSAQKLMDTEDVVAKARQAKAAGASRFCMGAAWRSPKDR--DIPKVAAMIREVK 123

Query: 164 GMGMEVCCTLGMLDKDQAGELKKAGLTAYNHNLDTSREYYPNIITTRTYDERLKTLEFVR 223
            MG+E C TLGMLD  QA  LK AGL  YNHNLDT+ +YY +II TR Y +RL TLE VR
Sbjct: 124 AMGLETCATLGMLDAGQARALKDAGLDYYNHNLDTAPDYYDSIIHTRQYQDRLNTLEHVR 183

Query: 224 DAGINVCSGGIIGLGEAEDDRVGLLHTLSTLPTHPESVPINALIAVKGTPLQDQKPVEIW 283
           D G+  C GGI+G+GE  + RVGLLH L+TLP HP+SVPIN L+ V GTPL   +P++ +
Sbjct: 184 DVGLKTCCGGIVGMGETREHRVGLLHALATLPAHPDSVPINQLVQVPGTPLHGTEPLDAF 243

Query: 284 EMIRMIATARITMPKAMVRLSAGRVRFSVPEQALCFLAGANSIFAGEKLLTTANNDFDAD 343
           E +RMIA ARI MPK+MVRLSAGR   S   QALCFLAGANSIF GEKLLTT N D + D
Sbjct: 244 EFVRMIAVARIAMPKSMVRLSAGREAMSDELQALCFLAGANSIFYGEKLLTTGNPDTERD 303

Query: 344 QLMFKVLGLLPKAPSLDDDE 363
           Q +F+ LGL P   ++D  E
Sbjct: 304 QGLFQRLGLRPMQITVDAAE 323


  Database: uniref100
    Posted date:  Jan 5, 2005  1:24 AM
  Number of letters in database: 848,049,833
  Number of sequences in database:  2,790,947
  
Lambda     K      H
   0.318    0.133    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 615,091,001
Number of Sequences: 2790947
Number of extensions: 24975893
Number of successful extensions: 57109
Number of sequences better than 10.0: 470
Number of HSP's better than 10.0 without gapping: 258
Number of HSP's successfully gapped in prelim test: 212
Number of HSP's that attempted gapping in prelim test: 56463
Number of HSP's gapped (non-prelim): 481
length of query: 377
length of database: 848,049,833
effective HSP length: 129
effective length of query: 248
effective length of database: 488,017,670
effective search space: 121028382160
effective search space used: 121028382160
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 75 (33.5 bits)