BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC144539.12 + phase: 0
(417 letters)
Database: uniref100
2,790,947 sequences; 848,049,833 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef100_Q8L7M8 Putative WD-40 repeat protein [Arabidopsis thal... 540 e-152
UniRef100_Q8RYE4 Hypothetical protein At2g47410 [Arabidopsis tha... 523 e-147
UniRef100_Q9FGX4 WD-40 repeat protein-like [Arabidopsis thaliana] 486 e-136
UniRef100_Q9SLN3 Putative WD-40 repeat protein [Arabidopsis thal... 410 e-113
UniRef100_Q8BSJ8 Mus musculus 12 days embryo male wolffian duct ... 179 1e-43
UniRef100_Q9ESL6 Neuronal differentiaion related protein [Mus mu... 179 2e-43
UniRef100_Q8VDD9 WD repeat domain 11 protein [Mus musculus] 179 2e-43
UniRef100_Q80VI6 Hypothetical protein [Mus musculus] 179 2e-43
UniRef100_Q96ME2 Hypothetical protein FLJ32477 [Homo sapiens] 179 2e-43
UniRef100_Q8WWQ0 WD repeat domain 11 protein [Homo sapiens] 179 2e-43
UniRef100_Q5VVH4 OTTHUMP00000016771 [Homo sapiens] 179 2e-43
UniRef100_UPI0000437E11 UPI0000437E11 UniRef100 entry 177 4e-43
UniRef100_UPI0000437E10 UPI0000437E10 UniRef100 entry 177 4e-43
UniRef100_UPI0000437E0F UPI0000437E0F UniRef100 entry 177 4e-43
UniRef100_Q5R2V1 WD repeat protein [Homo sapiens] 177 4e-43
UniRef100_Q5R2V0 WD repeat protein WDR9-form2 [Homo sapiens] 177 4e-43
UniRef100_Q96QH0 WDR9 protein, form A [Homo sapiens] 177 4e-43
UniRef100_Q96QG9 WDR9 protein, form B [Homo sapiens] 177 4e-43
UniRef100_Q9NSI6 WD-repeat protein 9 [Homo sapiens] 177 4e-43
UniRef100_UPI00003A9CE5 UPI00003A9CE5 UniRef100 entry 176 1e-42
>UniRef100_Q8L7M8 Putative WD-40 repeat protein [Arabidopsis thaliana]
Length = 1519
Score = 540 bits (1391), Expect = e-152
Identities = 275/407 (67%), Positives = 320/407 (78%), Gaps = 10/407 (2%)
Query: 16 SLKHLSSSKAPEKTQPDVANQNHDM-----DVDVDIGEVYFLIMRFLSAGPCHKTCSHLW 70
S + S + Q +V Q HD D+D+D+ EVYFLI+ FLS GPC +T HL
Sbjct: 7 STPFMEPSNLAKLVQGNVPLQPHDSHSSLTDLDMDLREVYFLILHFLSIGPCERTFGHLR 66
Query: 71 NELLENQLLPRRYHAWYSRSGASSGVPHDDGQSFPLEDYNKLAERYPHIEKDHLVKLLKQ 130
+E+LE LLPRRYH+W+SRSG SG DDG S PL Y+ L ERYPHIEKDHLVKLLKQ
Sbjct: 67 DEILEKGLLPRRYHSWWSRSGIYSGRADDDGISLPLS-YDNLIERYPHIEKDHLVKLLKQ 125
Query: 131 LLLNKASLSPGMSTGNPPNAADVPTLLGRGSFSLLSYDGDKVNEEVKPPPPYMRWPHTKA 190
L+LN + S GN PNAADVPTLLG G+FSL+ + +++ + Y+RWPH A
Sbjct: 126 LILNPSFPSHMRVEGNAPNAADVPTLLGSGTFSLVDRSNNIESQKARHVASYLRWPHMHA 185
Query: 191 NQVHGLHLREIGGGLPRHHRAPSIRAACYAIAKPSTMVQKMQNIKRIRGHCNAVYCAIFD 250
+QV GL LREIGGG +HHRAPSI +AC+AIAKPSTMVQKMQNIK++RGH NAVYCAIFD
Sbjct: 186 DQVRGLSLREIGGGFRKHHRAPSILSACHAIAKPSTMVQKMQNIKKLRGHRNAVYCAIFD 245
Query: 251 RSGRYVITGSDDRLVKIWSMETAYSLASCRGHVGDITDLAVSSNNALVASSSNDYIIRVW 310
RSGRYVITGSDDRLVKIWSMETA LASCRGH GDITDLAVSSNNALVAS+SND++IRVW
Sbjct: 246 RSGRYVITGSDDRLVKIWSMETALCLASCRGHEGDITDLAVSSNNALVASASNDFVIRVW 305
Query: 311 RLPDGLPISVLRGHTGAVTAIAFSPRPNAVYQLLSSSDDGTCRIWDARYTHSTPRLYVPK 370
RLPDG+PISVLRGHTGAVTAIAFSPR +VYQLLSSSDDGTCRIWDARY+ PR+YVP
Sbjct: 306 RLPDGMPISVLRGHTGAVTAIAFSPRQASVYQLLSSSDDGTCRIWDARYSQWLPRIYVPS 365
Query: 371 PSDSTGRSSGPSSNTMPQSHQIFCCAFNANGTVFVTGSSDNLARVYT 417
PSD+ ++G +SN QSHQI CCA+NANGT+FVTGSSD+ ARV++
Sbjct: 366 PSDA---NTGSTSNA-SQSHQILCCAYNANGTIFVTGSSDSNARVWS 408
>UniRef100_Q8RYE4 Hypothetical protein At2g47410 [Arabidopsis thaliana]
Length = 544
Score = 523 bits (1348), Expect = e-147
Identities = 273/420 (65%), Positives = 314/420 (74%), Gaps = 27/420 (6%)
Query: 16 SLKHLSSSKAPEKTQPDVANQNHDM-----DVDVDIGEVYFLIMRFLSAGPCHKTCSHLW 70
S + S + Q +V Q HD D+D+D+ EVYFLI+ FLS GPC +T HL
Sbjct: 7 STPFMEPSNLAKLVQGNVPLQPHDSHSSLTDLDMDLREVYFLILHFLSIGPCERTFGHLR 66
Query: 71 NELLENQLLPRRYHAWYSRSGASSGVPHDDGQSFPLEDYNKLAERYPHIEKDHLVKLLKQ 130
+E+LE LLPRRYH+W+SRSG SG DDG S PL Y+ L ERYPHIEKDHLVKLLKQ
Sbjct: 67 DEILEKGLLPRRYHSWWSRSGIYSGRADDDGISLPLS-YDNLIERYPHIEKDHLVKLLKQ 125
Query: 131 LLLNKASLSPGMSTGNPPNAADVPTLLGRGSFSLLSYDGDKVNEEVKPPPPYMRWPHTKA 190
L+LN + S GN PNAADVPTLLG G+FSL+ + +++ + Y+RWPH A
Sbjct: 126 LILNPSFPSHMRVEGNAPNAADVPTLLGSGTFSLVDRSNNIESQKARHVASYLRWPHMHA 185
Query: 191 NQVHGLHLREIGGGLPRHHRAPSIRAACYAIAKPSTMVQKMQNIKRIRGHCNAVYCAIFD 250
+QV GL LREIGGG +HHRAPSI +AC+AIAKPSTMVQKMQNIK++RGH NAVYCAIFD
Sbjct: 186 DQVRGLSLREIGGGFRKHHRAPSILSACHAIAKPSTMVQKMQNIKKLRGHRNAVYCAIFD 245
Query: 251 RSGRYVITGSDDRLVKIWSMETAYSLASCRGHVGDITDLAVSSNNALVASSSNDYIIRVW 310
RSGRYVITGSDDRLVKIWSMETA LASCRGH GDITDLAVSSNNALVAS+SND++IRVW
Sbjct: 246 RSGRYVITGSDDRLVKIWSMETALCLASCRGHEGDITDLAVSSNNALVASASNDFVIRVW 305
Query: 311 RLPDGLPISVLRGHTGAVTAIAFSPRPNAVYQLLSSSDDGTCRIWDARYTHSTPRLYVPK 370
RLPDG+PISVLRGHTGAVTAIAFSPR +SSDDGTCRIWDARY+ PR+YVP
Sbjct: 306 RLPDGMPISVLRGHTGAVTAIAFSPRQ-------ASSDDGTCRIWDARYSQWLPRIYVPS 358
Query: 371 PSDST---------GRSSGPSSNT-----MPQSHQIFCCAFNANGTVFVTGSSDNLARVY 416
PSD+ G S+ SSNT QSHQI CCA+NANGT+FVTGSSD+ ARVY
Sbjct: 359 PSDANTGSLEVSLLGESTFTSSNTGSTSNASQSHQILCCAYNANGTIFVTGSSDSNARVY 418
>UniRef100_Q9FGX4 WD-40 repeat protein-like [Arabidopsis thaliana]
Length = 1576
Score = 486 bits (1252), Expect = e-136
Identities = 250/382 (65%), Positives = 295/382 (76%), Gaps = 15/382 (3%)
Query: 1 MALQKYVPSGDAPTVSLKHLS-SSKAPEKTQ---PDVANQNHDMDVDVDIGEVYFLIMRF 56
MAL+K P GD+ ++ +K L+ S K P Q PD+ Q+ ++D+D+ EVYFL++
Sbjct: 1 MALRKNTPKGDSVSLPMKPLNFSRKLPGNVQIPDPDIV-QSVAPNIDLDLREVYFLMLHL 59
Query: 57 LSAGPCHKTCSHLWNELLENQLLPRRYHAWYSRSGASSGVPHDDGQSFPLEDYNKLAERY 116
LS+GPC KT + L +ELLE++LLPRRYHAWYSRSG SG +DDG SFPL +Y +LA+RY
Sbjct: 60 LSSGPCQKTYALLRHELLEHELLPRRYHAWYSRSGLPSGDENDDGNSFPL-NYTELAKRY 118
Query: 117 PHIEKDHLVKLLKQLLL--NKASLSPGMSTGNPPNAADVPTLLGRGSFSLLSYDGDKVNE 174
H++KDHLV+LLKQL+ N+ + S G+ GN A VPTLLG GSFSLLS D + V
Sbjct: 119 SHVKKDHLVELLKQLVFVSNRPNPSRGIGDGNKMIGAGVPTLLGTGSFSLLSSDKEIVGS 178
Query: 175 EVKPPPPYMRWPHTKANQVHGLHLREIGGGLPRHHRAPSIRAACYAIAKPSTMVQKMQNI 234
++KPPP MRWPH A+QV G+ LREIGGG RHHRAPSIRAACY IAKPS+MVQKMQNI
Sbjct: 179 DLKPPPIGMRWPHMHADQVRGISLREIGGGFARHHRAPSIRAACYVIAKPSSMVQKMQNI 238
Query: 235 KRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWSMETAYSLASCRGHVGDITDLAVSSN 294
KR+RGH NAVYCAI DRSGRYVITGSDDRLVK+WSM+TAY LASCRGH GDITDLAVSSN
Sbjct: 239 KRLRGHRNAVYCAILDRSGRYVITGSDDRLVKVWSMDTAYCLASCRGHEGDITDLAVSSN 298
Query: 295 NALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFSPRPNAVYQLLSSSDDGTCRI 354
N +AS+SND +IRVWRLPDGLP+SVLRGHTGAVTAIAFSPRP SSDDGTCRI
Sbjct: 299 NIFIASASNDCVIRVWRLPDGLPVSVLRGHTGAVTAIAFSPRP-------GSSDDGTCRI 351
Query: 355 WDARYTHSTPRLYVPKPSDSTG 376
WDAR PR+YVP+P G
Sbjct: 352 WDARGAQFAPRIYVPRPPSPDG 373
>UniRef100_Q9SLN3 Putative WD-40 repeat protein [Arabidopsis thaliana]
Length = 1269
Score = 410 bits (1053), Expect = e-113
Identities = 211/305 (69%), Positives = 239/305 (78%), Gaps = 21/305 (6%)
Query: 126 KLLKQLLLNKASLSPGMSTGNPPNAADVPTLLGRGSFSLLSYDGDKVNEEVKPPPPYMRW 185
KLLKQL+LN + S GN PNAADVPTLLG G+FSL+ + +++ + Y+RW
Sbjct: 1 KLLKQLILNPSFPSHMRVEGNAPNAADVPTLLGSGTFSLVDRSNNIESQKARHVASYLRW 60
Query: 186 PHTKANQVHGLHLREIGGGLPRHHRAPSIRAACYAIAKPSTMVQKMQNIKRIRGHCNAVY 245
PH A+QV GL LREIGGG +HHRAPSI +AC+AIAKPSTMVQKMQNIK++RGH NAVY
Sbjct: 61 PHMHADQVRGLSLREIGGGFRKHHRAPSILSACHAIAKPSTMVQKMQNIKKLRGHRNAVY 120
Query: 246 CAIFDRSGRYVITGSDDRLVKIWSMETAYSLASCRGHVGDITDLAVSSNNALVASSSNDY 305
CAIFDRSGRYVITGSDDRLVKIWSMETA LASCRGH GDITDLAVSSNNALVAS+SND+
Sbjct: 121 CAIFDRSGRYVITGSDDRLVKIWSMETALCLASCRGHEGDITDLAVSSNNALVASASNDF 180
Query: 306 IIRVWRLPDGLPISVLRGHTGAVTAIAFSPRPNAVYQLLSSSDDGTCRIWDARYTHSTPR 365
+IRVWRLPDG+PISVLRGHTGAVTAIAFSPR +SSDDGTCRIWDARY+ PR
Sbjct: 181 VIRVWRLPDGMPISVLRGHTGAVTAIAFSPRQ-------ASSDDGTCRIWDARYSQWLPR 233
Query: 366 LYVPKPSDST---------GRSSGPSSNT-----MPQSHQIFCCAFNANGTVFVTGSSDN 411
+YVP PSD+ G S+ SSNT QSHQI CCA+NANGT+FVTGSSD+
Sbjct: 234 IYVPSPSDANTGSLEVSLLGESTFTSSNTGSTSNASQSHQILCCAYNANGTIFVTGSSDS 293
Query: 412 LARVY 416
ARVY
Sbjct: 294 NARVY 298
>UniRef100_Q8BSJ8 Mus musculus 12 days embryo male wolffian duct includes surrounding
region cDNA, RIKEN full-length enriched library,
clone:6720454M04 product:neuronal differentiation
related protein, full insert sequence [Mus musculus]
Length = 755
Score = 179 bits (455), Expect = 1e-43
Identities = 129/382 (33%), Positives = 189/382 (48%), Gaps = 60/382 (15%)
Query: 48 EVYFLIMRFLSAGPCHKTCSHLWNELLENQLLPRRYHAWYSRSGASSGVPHDDGQSFPLE 107
E+YFLI RFL GPC + L E+ E +LLPRR W G+ P
Sbjct: 14 ELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTD-W-------------TGKEHP-R 58
Query: 108 DYNKLAERYPHIEKDHLVKLLKQLLLNKASLSPGMSTGNPPNAADVPTLLGRGSFSLLSY 167
Y L + Y H+ DHL+++ +L P + P + V TLLG G SLL
Sbjct: 59 TYQNLVKYYRHLAPDHLLQICHRL-------GPLLEQEIPQSVPGVQTLLGAGRQSLL-- 109
Query: 168 DGDKVNEEVKPPPPYMRWPHTKANQVHGLHLREIGGGLPRHHRAPSIRAACYAIAK---- 223
+ N+ K ++ W K + + LH + PSI ++
Sbjct: 110 ---RTNKSCK----HVVW---KGSALAALHCGRPPESPVNYGSPPSIADTLFSRKLNGKY 159
Query: 224 ------PSTMVQKMQNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWSMETAYSLA 277
P+ + Q M+ KRI GH ++VYC FDR+GR + TGSDD LVKIW+++ LA
Sbjct: 160 RLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWAIDDGRLLA 219
Query: 278 SCRGHVGDITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFSPRP 337
+ RGH +I+D+AV+ N ++A+ S D +IRVW L P++VL+GH+ ++T++ FSP
Sbjct: 220 TLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLC 279
Query: 338 NAVYQLLSSSD-DGTC--RIWDARYTHSTPRLYVPKPSDSTGRSSGPSSNTMPQSHQIFC 394
+ + LSS+ DGT +WDA PR P+ T R Q+ C
Sbjct: 280 SGSKRYLSSTGADGTICFWLWDAGTLKINPR-----PTKFTERPR--------PGVQMIC 326
Query: 395 CAFNANGTVFVTGSSDNLARVY 416
+F+A G TGS+D++ RVY
Sbjct: 327 SSFSAGGMFLATGSTDHIIRVY 348
Score = 43.9 bits (102), Expect = 0.008
Identities = 28/66 (42%), Positives = 36/66 (54%), Gaps = 5/66 (7%)
Query: 292 SSNNALVASSSNDYIIRVWRLPDGLP--ISVLRGHTGAVTAIAFSPRPNAVYQLLSSSDD 349
S+ +A+ S D+IIRV+ G P IS L HT V +I FS N + +S S D
Sbjct: 330 SAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFS---NTSNRFVSGSRD 386
Query: 350 GTCRIW 355
GT RIW
Sbjct: 387 GTARIW 392
Score = 40.4 bits (93), Expect = 0.094
Identities = 43/202 (21%), Positives = 72/202 (35%), Gaps = 20/202 (9%)
Query: 232 QNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWS------------METAYSLASC 279
+ I + H + V F + ++GS D +IW M T + +
Sbjct: 356 EKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQNL 415
Query: 280 RGHVGDITDLAVSS-----NNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFS 334
+G IT + V+ ++ V ++ N+ ++VW G I VL GH V
Sbjct: 416 QGIEDKITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEV--FVLE 473
Query: 335 PRPNAVYQLLSSSDDGTCRIWD-ARYTHSTPRLYVPKPSDSTGRSSGPSSNTMPQSHQIF 393
P P L S+ DG +WD AR + + G + P
Sbjct: 474 PHPFDPRVLFSAGHDGNVIVWDLARGVKVRSYFNMVFQIEGQGHGAVFDCKCSPDGQHFA 533
Query: 394 CCAFNANGTVFVTGSSDNLARV 415
C + + +F GSS ++
Sbjct: 534 CTDSHGHLLIFGFGSSSKYDKI 555
>UniRef100_Q9ESL6 Neuronal differentiaion related protein [Mus musculus]
Length = 1019
Score = 179 bits (453), Expect = 2e-43
Identities = 129/382 (33%), Positives = 188/382 (48%), Gaps = 60/382 (15%)
Query: 48 EVYFLIMRFLSAGPCHKTCSHLWNELLENQLLPRRYHAWYSRSGASSGVPHDDGQSFPLE 107
E+YFLI RFL GPC + L E+ E +LLPRR W G+ P
Sbjct: 14 ELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTD-W-------------TGKEHP-R 58
Query: 108 DYNKLAERYPHIEKDHLVKLLKQLLLNKASLSPGMSTGNPPNAADVPTLLGRGSFSLLSY 167
Y L + Y H+ DHL+++ +L P + P + V TLLG G SLL
Sbjct: 59 TYQNLVKYYRHLAPDHLLQICHRL-------GPLLEQEIPQSVPGVQTLLGAGRQSLL-- 109
Query: 168 DGDKVNEEVKPPPPYMRWPHTKANQVHGLHLREIGGGLPRHHRAPSIRAACYAIAK---- 223
+ N+ K ++ W K + + LH + PSI ++
Sbjct: 110 ---RTNKSCK----HVVW---KGSALAALHCGRPPESPVNYGSPPSIADTLFSRKLNGKY 159
Query: 224 ------PSTMVQKMQNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWSMETAYSLA 277
P+ + Q M+ KRI GH ++VYC FDR+GR + TGSDD LVKIW+ + LA
Sbjct: 160 RLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLA 219
Query: 278 SCRGHVGDITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFSPRP 337
+ RGH +I+D+AV+ N ++A+ S D +IRVW L P++VL+GH+ ++T++ FSP
Sbjct: 220 TLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLC 279
Query: 338 NAVYQLLSSSD-DGTC--RIWDARYTHSTPRLYVPKPSDSTGRSSGPSSNTMPQSHQIFC 394
+ + LSS+ DGT +WDA PR P+ T R Q+ C
Sbjct: 280 SGSKRYLSSTGADGTICFWLWDAGTLKINPR-----PTKFTERPR--------PGVQMIC 326
Query: 395 CAFNANGTVFVTGSSDNLARVY 416
+F+A G TGS+D++ RVY
Sbjct: 327 SSFSAGGMFLATGSTDHIIRVY 348
Score = 43.9 bits (102), Expect = 0.008
Identities = 28/66 (42%), Positives = 36/66 (54%), Gaps = 5/66 (7%)
Query: 292 SSNNALVASSSNDYIIRVWRLPDGLP--ISVLRGHTGAVTAIAFSPRPNAVYQLLSSSDD 349
S+ +A+ S D+IIRV+ G P IS L HT V +I FS N + +S S D
Sbjct: 330 SAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFS---NTSNRFVSGSRD 386
Query: 350 GTCRIW 355
GT RIW
Sbjct: 387 GTARIW 392
Score = 39.7 bits (91), Expect = 0.16
Identities = 34/142 (23%), Positives = 55/142 (37%), Gaps = 19/142 (13%)
Query: 232 QNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWS------------METAYSLASC 279
+ I + H + V F + ++GS D +IW M T + +
Sbjct: 356 EKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQNL 415
Query: 280 RGHVGDITDLAVSS-----NNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFS 334
+G IT + V+ ++ V ++ N+ ++VW G I VL GH V
Sbjct: 416 QGIEDKITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEV--FVLE 473
Query: 335 PRPNAVYQLLSSSDDGTCRIWD 356
P P L S+ DG +WD
Sbjct: 474 PHPFDPRVLFSAGHDGNVIVWD 495
>UniRef100_Q8VDD9 WD repeat domain 11 protein [Mus musculus]
Length = 1779
Score = 179 bits (453), Expect = 2e-43
Identities = 129/382 (33%), Positives = 188/382 (48%), Gaps = 60/382 (15%)
Query: 48 EVYFLIMRFLSAGPCHKTCSHLWNELLENQLLPRRYHAWYSRSGASSGVPHDDGQSFPLE 107
E+YFLI RFL GPC + L E+ E +LLPRR W G+ P
Sbjct: 14 ELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTD-W-------------TGKEHP-R 58
Query: 108 DYNKLAERYPHIEKDHLVKLLKQLLLNKASLSPGMSTGNPPNAADVPTLLGRGSFSLLSY 167
Y L + Y H+ DHL+++ +L P + P + V TLLG G SLL
Sbjct: 59 TYQNLVKYYRHLAPDHLLQICHRL-------GPLLEQEIPQSVPGVQTLLGAGRQSLL-- 109
Query: 168 DGDKVNEEVKPPPPYMRWPHTKANQVHGLHLREIGGGLPRHHRAPSIRAACYAIAK---- 223
+ N+ K ++ W K + + LH + PSI ++
Sbjct: 110 ---RTNKSCK----HVVW---KGSALAALHCGRPPESPVNYGSPPSIADTLFSRKLNGKY 159
Query: 224 ------PSTMVQKMQNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWSMETAYSLA 277
P+ + Q M+ KRI GH ++VYC FDR+GR + TGSDD LVKIW+ + LA
Sbjct: 160 RLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLA 219
Query: 278 SCRGHVGDITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFSPRP 337
+ RGH +I+D+AV+ N ++A+ S D +IRVW L P++VL+GH+ ++T++ FSP
Sbjct: 220 TLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLC 279
Query: 338 NAVYQLLSSSD-DGTC--RIWDARYTHSTPRLYVPKPSDSTGRSSGPSSNTMPQSHQIFC 394
+ + LSS+ DGT +WDA PR P+ T R Q+ C
Sbjct: 280 SGSKRYLSSTGADGTICFWLWDAGTLKINPR-----PTKFTERPR--------PGVQMIC 326
Query: 395 CAFNANGTVFVTGSSDNLARVY 416
+F+A G TGS+D++ RVY
Sbjct: 327 SSFSAGGMFLATGSTDHIIRVY 348
Score = 43.9 bits (102), Expect = 0.008
Identities = 28/66 (42%), Positives = 36/66 (54%), Gaps = 5/66 (7%)
Query: 292 SSNNALVASSSNDYIIRVWRLPDGLP--ISVLRGHTGAVTAIAFSPRPNAVYQLLSSSDD 349
S+ +A+ S D+IIRV+ G P IS L HT V +I FS N + +S S D
Sbjct: 330 SAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFS---NTSNRFVSGSRD 386
Query: 350 GTCRIW 355
GT RIW
Sbjct: 387 GTARIW 392
Score = 39.7 bits (91), Expect = 0.16
Identities = 34/142 (23%), Positives = 55/142 (37%), Gaps = 19/142 (13%)
Query: 232 QNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWS------------METAYSLASC 279
+ I + H + V F + ++GS D +IW M T + +
Sbjct: 356 EKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQNL 415
Query: 280 RGHVGDITDLAVSS-----NNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFS 334
+G IT + V+ ++ V ++ N+ ++VW G I VL GH V
Sbjct: 416 QGIEDKITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEV--FVLE 473
Query: 335 PRPNAVYQLLSSSDDGTCRIWD 356
P P L S+ DG +WD
Sbjct: 474 PHPFDPRVLFSAGHDGNVIVWD 495
>UniRef100_Q80VI6 Hypothetical protein [Mus musculus]
Length = 896
Score = 179 bits (453), Expect = 2e-43
Identities = 129/382 (33%), Positives = 188/382 (48%), Gaps = 60/382 (15%)
Query: 48 EVYFLIMRFLSAGPCHKTCSHLWNELLENQLLPRRYHAWYSRSGASSGVPHDDGQSFPLE 107
E+YFLI RFL GPC + L E+ E +LLPRR W G+ P
Sbjct: 14 ELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTD-W-------------TGKEHP-R 58
Query: 108 DYNKLAERYPHIEKDHLVKLLKQLLLNKASLSPGMSTGNPPNAADVPTLLGRGSFSLLSY 167
Y L + Y H+ DHL+++ +L P + P + V TLLG G SLL
Sbjct: 59 TYQNLVKYYRHLAPDHLLQICHRL-------GPLLEQEIPQSVPGVQTLLGAGRQSLL-- 109
Query: 168 DGDKVNEEVKPPPPYMRWPHTKANQVHGLHLREIGGGLPRHHRAPSIRAACYAIAK---- 223
+ N+ K ++ W K + + LH + PSI ++
Sbjct: 110 ---RTNKSCK----HVVW---KGSALAALHCGRPPESPVNYGSPPSIADTLFSRKLNGKY 159
Query: 224 ------PSTMVQKMQNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWSMETAYSLA 277
P+ + Q M+ KRI GH ++VYC FDR+GR + TGSDD LVKIW+ + LA
Sbjct: 160 RLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLA 219
Query: 278 SCRGHVGDITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFSPRP 337
+ RGH +I+D+AV+ N ++A+ S D +IRVW L P++VL+GH+ ++T++ FSP
Sbjct: 220 TLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLC 279
Query: 338 NAVYQLLSSSD-DGTC--RIWDARYTHSTPRLYVPKPSDSTGRSSGPSSNTMPQSHQIFC 394
+ + LSS+ DGT +WDA PR P+ T R Q+ C
Sbjct: 280 SGSKRYLSSTGADGTICFWLWDAGTLKINPR-----PTKFTERPR--------PGVQMIC 326
Query: 395 CAFNANGTVFVTGSSDNLARVY 416
+F+A G TGS+D++ RVY
Sbjct: 327 SSFSAGGMFLATGSTDHIIRVY 348
Score = 43.9 bits (102), Expect = 0.008
Identities = 28/66 (42%), Positives = 36/66 (54%), Gaps = 5/66 (7%)
Query: 292 SSNNALVASSSNDYIIRVWRLPDGLP--ISVLRGHTGAVTAIAFSPRPNAVYQLLSSSDD 349
S+ +A+ S D+IIRV+ G P IS L HT V +I FS N + +S S D
Sbjct: 330 SAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFS---NTSNRFVSGSRD 386
Query: 350 GTCRIW 355
GT RIW
Sbjct: 387 GTARIW 392
Score = 39.7 bits (91), Expect = 0.16
Identities = 34/142 (23%), Positives = 55/142 (37%), Gaps = 19/142 (13%)
Query: 232 QNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWS------------METAYSLASC 279
+ I + H + V F + ++GS D +IW M T + +
Sbjct: 356 EKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQNL 415
Query: 280 RGHVGDITDLAVSS-----NNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFS 334
+G IT + V+ ++ V ++ N+ ++VW G I VL GH V
Sbjct: 416 QGIEDKITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEV--FVLE 473
Query: 335 PRPNAVYQLLSSSDDGTCRIWD 356
P P L S+ DG +WD
Sbjct: 474 PHPFDPRVLFSAGHDGNVIVWD 495
>UniRef100_Q96ME2 Hypothetical protein FLJ32477 [Homo sapiens]
Length = 912
Score = 179 bits (453), Expect = 2e-43
Identities = 129/382 (33%), Positives = 188/382 (48%), Gaps = 60/382 (15%)
Query: 48 EVYFLIMRFLSAGPCHKTCSHLWNELLENQLLPRRYHAWYSRSGASSGVPHDDGQSFPLE 107
E+YFLI RFL GPC + L E+ E +LLPRR W G+ P
Sbjct: 14 ELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTD-W-------------TGKEHP-R 58
Query: 108 DYNKLAERYPHIEKDHLVKLLKQLLLNKASLSPGMSTGNPPNAADVPTLLGRGSFSLLSY 167
Y L + Y H+ DHL+++ +L P + P + V TLLG G SLL
Sbjct: 59 TYQNLVKYYRHLAPDHLLQICHRL-------GPLLEQEIPQSVPGVQTLLGAGRQSLL-- 109
Query: 168 DGDKVNEEVKPPPPYMRWPHTKANQVHGLHLREIGGGLPRHHRAPSIRAACYAIAK---- 223
+ N+ K ++ W K + + LH + PSI ++
Sbjct: 110 ---RTNKSCK----HVVW---KGSALAALHCGRPPESPVNYGSPPSIADTLFSRKLNGKY 159
Query: 224 ------PSTMVQKMQNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWSMETAYSLA 277
P+ + Q M+ KRI GH ++VYC FDR+GR + TGSDD LVKIW+ + LA
Sbjct: 160 RLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLA 219
Query: 278 SCRGHVGDITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFSPRP 337
+ RGH +I+D+AV+ N ++A+ S D +IRVW L P++VL+GH+ ++T++ FSP
Sbjct: 220 TLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLC 279
Query: 338 NAVYQLLSSSD-DGTC--RIWDARYTHSTPRLYVPKPSDSTGRSSGPSSNTMPQSHQIFC 394
+ + LSS+ DGT +WDA PR P+ T R Q+ C
Sbjct: 280 SGSKRYLSSTGADGTICFWLWDAGTLKINPR-----PAKFTERPR--------PGVQMIC 326
Query: 395 CAFNANGTVFVTGSSDNLARVY 416
+F+A G TGS+D++ RVY
Sbjct: 327 SSFSAGGMFLATGSTDHIIRVY 348
Score = 43.9 bits (102), Expect = 0.008
Identities = 28/66 (42%), Positives = 36/66 (54%), Gaps = 5/66 (7%)
Query: 292 SSNNALVASSSNDYIIRVWRLPDGLP--ISVLRGHTGAVTAIAFSPRPNAVYQLLSSSDD 349
S+ +A+ S D+IIRV+ G P IS L HT V +I FS N + +S S D
Sbjct: 330 SAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFS---NTSNRFVSGSRD 386
Query: 350 GTCRIW 355
GT RIW
Sbjct: 387 GTARIW 392
Score = 39.7 bits (91), Expect = 0.16
Identities = 34/142 (23%), Positives = 55/142 (37%), Gaps = 19/142 (13%)
Query: 232 QNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWS------------METAYSLASC 279
+ I + H + V F + ++GS D +IW M T + +
Sbjct: 356 EKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQNL 415
Query: 280 RGHVGDITDLAVSS-----NNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFS 334
+G IT + V+ ++ V ++ N+ ++VW G I VL GH V
Sbjct: 416 QGIEDKITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEV--FVLE 473
Query: 335 PRPNAVYQLLSSSDDGTCRIWD 356
P P L S+ DG +WD
Sbjct: 474 PHPFDPRVLFSAGHDGNVIVWD 495
>UniRef100_Q8WWQ0 WD repeat domain 11 protein [Homo sapiens]
Length = 1821
Score = 179 bits (453), Expect = 2e-43
Identities = 129/382 (33%), Positives = 188/382 (48%), Gaps = 60/382 (15%)
Query: 48 EVYFLIMRFLSAGPCHKTCSHLWNELLENQLLPRRYHAWYSRSGASSGVPHDDGQSFPLE 107
E+YFLI RFL GPC + L E+ E +LLPRR W G+ P
Sbjct: 14 ELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTD-W-------------TGKEHP-R 58
Query: 108 DYNKLAERYPHIEKDHLVKLLKQLLLNKASLSPGMSTGNPPNAADVPTLLGRGSFSLLSY 167
Y L + Y H+ DHL+++ +L P + P + V TLLG G SLL
Sbjct: 59 TYQNLVKYYRHLAPDHLLQICHRL-------GPLLEQEIPQSVPGVQTLLGAGRQSLL-- 109
Query: 168 DGDKVNEEVKPPPPYMRWPHTKANQVHGLHLREIGGGLPRHHRAPSIRAACYAIAK---- 223
+ N+ K ++ W K + + LH + PSI ++
Sbjct: 110 ---RTNKSCK----HVVW---KGSALAALHCGRPPESPVNYGSPPSIADTLFSRKLNGKY 159
Query: 224 ------PSTMVQKMQNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWSMETAYSLA 277
P+ + Q M+ KRI GH ++VYC FDR+GR + TGSDD LVKIW+ + LA
Sbjct: 160 RLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLA 219
Query: 278 SCRGHVGDITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFSPRP 337
+ RGH +I+D+AV+ N ++A+ S D +IRVW L P++VL+GH+ ++T++ FSP
Sbjct: 220 TLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLC 279
Query: 338 NAVYQLLSSSD-DGTC--RIWDARYTHSTPRLYVPKPSDSTGRSSGPSSNTMPQSHQIFC 394
+ + LSS+ DGT +WDA PR P+ T R Q+ C
Sbjct: 280 SGSKRYLSSTGADGTICFWLWDAGTLKINPR-----PAKFTERPR--------PGVQMIC 326
Query: 395 CAFNANGTVFVTGSSDNLARVY 416
+F+A G TGS+D++ RVY
Sbjct: 327 SSFSAGGMFLATGSTDHIIRVY 348
Score = 43.9 bits (102), Expect = 0.008
Identities = 28/66 (42%), Positives = 36/66 (54%), Gaps = 5/66 (7%)
Query: 292 SSNNALVASSSNDYIIRVWRLPDGLP--ISVLRGHTGAVTAIAFSPRPNAVYQLLSSSDD 349
S+ +A+ S D+IIRV+ G P IS L HT V +I FS N + +S S D
Sbjct: 330 SAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFS---NTSNRFVSGSRD 386
Query: 350 GTCRIW 355
GT RIW
Sbjct: 387 GTARIW 392
Score = 39.7 bits (91), Expect = 0.16
Identities = 34/142 (23%), Positives = 55/142 (37%), Gaps = 19/142 (13%)
Query: 232 QNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWS------------METAYSLASC 279
+ I + H + V F + ++GS D +IW M T + +
Sbjct: 356 EKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQNL 415
Query: 280 RGHVGDITDLAVSS-----NNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFS 334
+G IT + V+ ++ V ++ N+ ++VW G I VL GH V
Sbjct: 416 QGIEDKITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEV--FVLE 473
Query: 335 PRPNAVYQLLSSSDDGTCRIWD 356
P P L S+ DG +WD
Sbjct: 474 PHPFDPRVLFSAGHDGNVIVWD 495
>UniRef100_Q5VVH4 OTTHUMP00000016771 [Homo sapiens]
Length = 1821
Score = 179 bits (453), Expect = 2e-43
Identities = 129/382 (33%), Positives = 188/382 (48%), Gaps = 60/382 (15%)
Query: 48 EVYFLIMRFLSAGPCHKTCSHLWNELLENQLLPRRYHAWYSRSGASSGVPHDDGQSFPLE 107
E+YFLI RFL GPC + L E+ E +LLPRR W G+ P
Sbjct: 14 ELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTD-W-------------TGKEHP-R 58
Query: 108 DYNKLAERYPHIEKDHLVKLLKQLLLNKASLSPGMSTGNPPNAADVPTLLGRGSFSLLSY 167
Y L + Y H+ DHL+++ +L P + P + V TLLG G SLL
Sbjct: 59 TYQNLVKYYRHLAPDHLLQICHRL-------GPLLEQEIPQSVPGVQTLLGAGRQSLL-- 109
Query: 168 DGDKVNEEVKPPPPYMRWPHTKANQVHGLHLREIGGGLPRHHRAPSIRAACYAIAK---- 223
+ N+ K ++ W K + + LH + PSI ++
Sbjct: 110 ---RTNKSCK----HVVW---KGSALAALHCGRPPESPVNYGSPPSIADTLFSRKLNGKY 159
Query: 224 ------PSTMVQKMQNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWSMETAYSLA 277
P+ + Q M+ KRI GH ++VYC FDR+GR + TGSDD LVKIW+ + LA
Sbjct: 160 RLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLA 219
Query: 278 SCRGHVGDITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFSPRP 337
+ RGH +I+D+AV+ N ++A+ S D +IRVW L P++VL+GH+ ++T++ FSP
Sbjct: 220 TLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLC 279
Query: 338 NAVYQLLSSSD-DGTC--RIWDARYTHSTPRLYVPKPSDSTGRSSGPSSNTMPQSHQIFC 394
+ + LSS+ DGT +WDA PR P+ T R Q+ C
Sbjct: 280 SGSKRYLSSTGADGTICFWLWDAGTLKINPR-----PAKFTERPR--------PGVQMIC 326
Query: 395 CAFNANGTVFVTGSSDNLARVY 416
+F+A G TGS+D++ RVY
Sbjct: 327 SSFSAGGMFLATGSTDHIIRVY 348
Score = 43.9 bits (102), Expect = 0.008
Identities = 28/66 (42%), Positives = 36/66 (54%), Gaps = 5/66 (7%)
Query: 292 SSNNALVASSSNDYIIRVWRLPDGLP--ISVLRGHTGAVTAIAFSPRPNAVYQLLSSSDD 349
S+ +A+ S D+IIRV+ G P IS L HT V +I FS N + +S S D
Sbjct: 330 SAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFS---NTSNRFVSGSRD 386
Query: 350 GTCRIW 355
GT RIW
Sbjct: 387 GTARIW 392
Score = 39.7 bits (91), Expect = 0.16
Identities = 34/142 (23%), Positives = 55/142 (37%), Gaps = 19/142 (13%)
Query: 232 QNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWS------------METAYSLASC 279
+ I + H + V F + ++GS D +IW M T + +
Sbjct: 356 EKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQNL 415
Query: 280 RGHVGDITDLAVSS-----NNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFS 334
+G IT + V+ ++ V ++ N+ ++VW G I VL GH V
Sbjct: 416 QGIEDKITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEV--FVLE 473
Query: 335 PRPNAVYQLLSSSDDGTCRIWD 356
P P L S+ DG +WD
Sbjct: 474 PHPFDPRVLFSAGHDGNVIVWD 495
>UniRef100_UPI0000437E11 UPI0000437E11 UniRef100 entry
Length = 1797
Score = 177 bits (450), Expect = 4e-43
Identities = 126/392 (32%), Positives = 188/392 (47%), Gaps = 80/392 (20%)
Query: 48 EVYFLIMRFLSAGPCHKTCSHLWNELLENQLLPRRYHAWYSRSGASSGVPHDDGQSFPLE 107
E+YFLI RFL AGPC L E+ + +LLP+R W + S
Sbjct: 14 ELYFLIARFLEAGPCQDAAETLIREVQQKELLPKRID-WTGKEHPGS------------- 59
Query: 108 DYNKLAERYPHIEKDHLVKLLKQLLLNKASLSPGMSTGNPPNAADVPTLLGRGSFSLLSY 167
Y L + Y HI DHL+++ +++ SP + P + V +LLG G S+L
Sbjct: 60 -YENLVKLYRHISPDHLLQVCERV-------SPLLEREVPASVPGVNSLLGTGRQSVL-- 109
Query: 168 DGDKVNEEVK----------------PPPPYMRWPHTKANQVHGLHLREIGGGLPRHHRA 211
+ N+ K PP P + + + N +H R + G
Sbjct: 110 ---RTNKSCKHVVWKGSALAALHCGRPPEPPVIFG-SPPNIAETIHSRRLNGS------- 158
Query: 212 PSIRAACYAIAK--PSTMVQKMQNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWS 269
Y + + P+ + Q M+ KRI GH ++VYC FDR+GR + TGSDD LVKIW+
Sbjct: 159 -------YRLGQLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWA 211
Query: 270 METAYSLASCRGHVGDITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVT 329
+ + LA+ RGH +I+D+AV+ N L+A+ S D +IRVW L P++VL GH ++T
Sbjct: 212 TDDGHLLATLRGHAAEISDMAVNYENTLLAAGSCDKMIRVWCLQTCAPLAVLEGHAASIT 271
Query: 330 AIAFSPRPNAVYQLLSSSD-DGTCRI--WDARYTH--STPRLYVPKPSDSTGRSSGPSSN 384
++ FSP + + LSS+ DGT WDAR P ++ +P
Sbjct: 272 SLQFSPLCSGNKRFLSSTGADGTICFWQWDARTLKFGQRPSKFIERPRPGV--------- 322
Query: 385 TMPQSHQIFCCAFNANGTVFVTGSSDNLARVY 416
Q+ C +F+A G TGS+D++ RVY
Sbjct: 323 ------QMICSSFSAGGMFLATGSTDHIIRVY 348
Score = 44.3 bits (103), Expect = 0.007
Identities = 35/143 (24%), Positives = 55/143 (37%), Gaps = 20/143 (13%)
Query: 232 QNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWSMETA----------------YS 275
+ I + H + V F SG ++GS D +IW ++ Y+
Sbjct: 356 EKISELESHTDKVDSIQFSHSGDRFVSGSRDGTARIWQLQQQDWRSILLDMATKLPGKYN 415
Query: 276 LASCRGHVGD--ITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAF 333
V +T +A N+ V +++N+ ++VW G I VL GH V
Sbjct: 416 PPPLEDKVTKLKVTMVAWDCNDNTVITAANNLTLKVWNSYTGNLIHVLMGHEDEV--FVL 473
Query: 334 SPRPNAVYQLLSSSDDGTCRIWD 356
P P L S+ DG +WD
Sbjct: 474 EPHPFDSRVLFSAGHDGNAIVWD 496
Score = 43.9 bits (102), Expect = 0.008
Identities = 33/127 (25%), Positives = 59/127 (45%), Gaps = 6/127 (4%)
Query: 292 SSNNALVASSSNDYIIRVWRLPDGLP--ISVLRGHTGAVTAIAFSPRPNAVYQLLSSSDD 349
S+ +A+ S D+IIRV+ G P IS L HT V +I FS ++ + +S S D
Sbjct: 330 SAGGMFLATGSTDHIIRVYYFGGGQPEKISELESHTDKVDSIQFS---HSGDRFVSGSRD 386
Query: 350 GTCRIWDARYTHSTPRLYVPKPSDSTGRSSGPSSNTMPQSHQIFCCAFNANGTVFVTGSS 409
GT RIW + + + + G+ + P ++ A++ N +T ++
Sbjct: 387 GTARIWQLQ-QQDWRSILLDMATKLPGKYNPPPLEDKVTKLKVTMVAWDCNDNTVITAAN 445
Query: 410 DNLARVY 416
+ +V+
Sbjct: 446 NLTLKVW 452
>UniRef100_UPI0000437E10 UPI0000437E10 UniRef100 entry
Length = 895
Score = 177 bits (450), Expect = 4e-43
Identities = 126/392 (32%), Positives = 188/392 (47%), Gaps = 80/392 (20%)
Query: 48 EVYFLIMRFLSAGPCHKTCSHLWNELLENQLLPRRYHAWYSRSGASSGVPHDDGQSFPLE 107
E+YFLI RFL AGPC L E+ + +LLP+R W + S
Sbjct: 14 ELYFLIARFLEAGPCQDAAETLIREVQQKELLPKRID-WTGKEHPGS------------- 59
Query: 108 DYNKLAERYPHIEKDHLVKLLKQLLLNKASLSPGMSTGNPPNAADVPTLLGRGSFSLLSY 167
Y L + Y HI DHL+++ +++ SP + P + V +LLG G S+L
Sbjct: 60 -YENLVKLYRHISPDHLLQVCERV-------SPLLEREVPASVPGVNSLLGTGRQSVL-- 109
Query: 168 DGDKVNEEVK----------------PPPPYMRWPHTKANQVHGLHLREIGGGLPRHHRA 211
+ N+ K PP P + + + N +H R + G
Sbjct: 110 ---RTNKSCKHVVWKGSALAALHCGRPPEPPVIFG-SPPNIAETIHSRRLNGS------- 158
Query: 212 PSIRAACYAIAK--PSTMVQKMQNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWS 269
Y + + P+ + Q M+ KRI GH ++VYC FDR+GR + TGSDD LVKIW+
Sbjct: 159 -------YRLGQLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWA 211
Query: 270 METAYSLASCRGHVGDITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVT 329
+ + LA+ RGH +I+D+AV+ N L+A+ S D +IRVW L P++VL GH ++T
Sbjct: 212 TDDGHLLATLRGHAAEISDMAVNYENTLLAAGSCDKMIRVWCLQTCAPLAVLEGHAASIT 271
Query: 330 AIAFSPRPNAVYQLLSSSD-DGTCRI--WDARYTH--STPRLYVPKPSDSTGRSSGPSSN 384
++ FSP + + LSS+ DGT WDAR P ++ +P
Sbjct: 272 SLQFSPLCSGNKRFLSSTGADGTICFWQWDARTLKFGQRPSKFIERPRPGV--------- 322
Query: 385 TMPQSHQIFCCAFNANGTVFVTGSSDNLARVY 416
Q+ C +F+A G TGS+D++ RVY
Sbjct: 323 ------QMICSSFSAGGMFLATGSTDHIIRVY 348
Score = 44.3 bits (103), Expect = 0.007
Identities = 35/143 (24%), Positives = 55/143 (37%), Gaps = 20/143 (13%)
Query: 232 QNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWSMETA----------------YS 275
+ I + H + V F SG ++GS D +IW ++ Y+
Sbjct: 356 EKISELESHTDKVDSIQFSHSGDRFVSGSRDGTARIWQLQQQDWRSILLDMATKLPGKYN 415
Query: 276 LASCRGHVGD--ITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAF 333
V +T +A N+ V +++N+ ++VW G I VL GH V
Sbjct: 416 PPPLEDKVTKLKVTMVAWDCNDNTVITAANNLTLKVWNSYTGNLIHVLMGHEDEV--FVL 473
Query: 334 SPRPNAVYQLLSSSDDGTCRIWD 356
P P L S+ DG +WD
Sbjct: 474 EPHPFDSRVLFSAGHDGNAIVWD 496
Score = 43.9 bits (102), Expect = 0.008
Identities = 33/127 (25%), Positives = 59/127 (45%), Gaps = 6/127 (4%)
Query: 292 SSNNALVASSSNDYIIRVWRLPDGLP--ISVLRGHTGAVTAIAFSPRPNAVYQLLSSSDD 349
S+ +A+ S D+IIRV+ G P IS L HT V +I FS ++ + +S S D
Sbjct: 330 SAGGMFLATGSTDHIIRVYYFGGGQPEKISELESHTDKVDSIQFS---HSGDRFVSGSRD 386
Query: 350 GTCRIWDARYTHSTPRLYVPKPSDSTGRSSGPSSNTMPQSHQIFCCAFNANGTVFVTGSS 409
GT RIW + + + + G+ + P ++ A++ N +T ++
Sbjct: 387 GTARIWQLQ-QQDWRSILLDMATKLPGKYNPPPLEDKVTKLKVTMVAWDCNDNTVITAAN 445
Query: 410 DNLARVY 416
+ +V+
Sbjct: 446 NLTLKVW 452
>UniRef100_UPI0000437E0F UPI0000437E0F UniRef100 entry
Length = 974
Score = 177 bits (450), Expect = 4e-43
Identities = 126/392 (32%), Positives = 188/392 (47%), Gaps = 80/392 (20%)
Query: 48 EVYFLIMRFLSAGPCHKTCSHLWNELLENQLLPRRYHAWYSRSGASSGVPHDDGQSFPLE 107
E+YFLI RFL AGPC L E+ + +LLP+R W + S
Sbjct: 14 ELYFLIARFLEAGPCQDAAETLIREVQQKELLPKRID-WTGKEHPGS------------- 59
Query: 108 DYNKLAERYPHIEKDHLVKLLKQLLLNKASLSPGMSTGNPPNAADVPTLLGRGSFSLLSY 167
Y L + Y HI DHL+++ +++ SP + P + V +LLG G S+L
Sbjct: 60 -YENLVKLYRHISPDHLLQVCERV-------SPLLEREVPASVPGVNSLLGTGRQSVL-- 109
Query: 168 DGDKVNEEVK----------------PPPPYMRWPHTKANQVHGLHLREIGGGLPRHHRA 211
+ N+ K PP P + + + N +H R + G
Sbjct: 110 ---RTNKSCKHVVWKGSALAALHCGRPPEPPVIFG-SPPNIAETIHSRRLNGS------- 158
Query: 212 PSIRAACYAIAK--PSTMVQKMQNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWS 269
Y + + P+ + Q M+ KRI GH ++VYC FDR+GR + TGSDD LVKIW+
Sbjct: 159 -------YRLGQLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWA 211
Query: 270 METAYSLASCRGHVGDITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVT 329
+ + LA+ RGH +I+D+AV+ N L+A+ S D +IRVW L P++VL GH ++T
Sbjct: 212 TDDGHLLATLRGHAAEISDMAVNYENTLLAAGSCDKMIRVWCLQTCAPLAVLEGHAASIT 271
Query: 330 AIAFSPRPNAVYQLLSSSD-DGTCRI--WDARYTH--STPRLYVPKPSDSTGRSSGPSSN 384
++ FSP + + LSS+ DGT WDAR P ++ +P
Sbjct: 272 SLQFSPLCSGNKRFLSSTGADGTICFWQWDARTLKFGQRPSKFIERPRPGV--------- 322
Query: 385 TMPQSHQIFCCAFNANGTVFVTGSSDNLARVY 416
Q+ C +F+A G TGS+D++ RVY
Sbjct: 323 ------QMICSSFSAGGMFLATGSTDHIIRVY 348
Score = 44.3 bits (103), Expect = 0.007
Identities = 35/143 (24%), Positives = 55/143 (37%), Gaps = 20/143 (13%)
Query: 232 QNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWSMETA----------------YS 275
+ I + H + V F SG ++GS D +IW ++ Y+
Sbjct: 356 EKISELESHTDKVDSIQFSHSGDRFVSGSRDGTARIWQLQQQDWRSILLDMATKLPGKYN 415
Query: 276 LASCRGHVGD--ITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAF 333
V +T +A N+ V +++N+ ++VW G I VL GH V
Sbjct: 416 PPPLEDKVTKLKVTMVAWDCNDNTVITAANNLTLKVWNSYTGNLIHVLMGHEDEV--FVL 473
Query: 334 SPRPNAVYQLLSSSDDGTCRIWD 356
P P L S+ DG +WD
Sbjct: 474 EPHPFDSRVLFSAGHDGNAIVWD 496
Score = 43.9 bits (102), Expect = 0.008
Identities = 33/127 (25%), Positives = 59/127 (45%), Gaps = 6/127 (4%)
Query: 292 SSNNALVASSSNDYIIRVWRLPDGLP--ISVLRGHTGAVTAIAFSPRPNAVYQLLSSSDD 349
S+ +A+ S D+IIRV+ G P IS L HT V +I FS ++ + +S S D
Sbjct: 330 SAGGMFLATGSTDHIIRVYYFGGGQPEKISELESHTDKVDSIQFS---HSGDRFVSGSRD 386
Query: 350 GTCRIWDARYTHSTPRLYVPKPSDSTGRSSGPSSNTMPQSHQIFCCAFNANGTVFVTGSS 409
GT RIW + + + + G+ + P ++ A++ N +T ++
Sbjct: 387 GTARIWQLQ-QQDWRSILLDMATKLPGKYNPPPLEDKVTKLKVTMVAWDCNDNTVITAAN 445
Query: 410 DNLARVY 416
+ +V+
Sbjct: 446 NLTLKVW 452
>UniRef100_Q5R2V1 WD repeat protein [Homo sapiens]
Length = 2269
Score = 177 bits (450), Expect = 4e-43
Identities = 127/379 (33%), Positives = 186/379 (48%), Gaps = 54/379 (14%)
Query: 48 EVYFLIMRFLSAGPCHKTCSHLWNELLENQLLPRRYHAWYSRSGASSGVPHDDGQSFPLE 107
E+YFLI R+LSAGPC + L EL + QLLP+R W G H+
Sbjct: 17 ELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLD-W-------EGNEHN-------R 61
Query: 108 DYNKLAERYPHIEKDHLVKLLKQLLLNKASLSPGMSTGNPPNAADVPTLLGRGSFSLLSY 167
Y +L H+ DHL+++ +++ P + PP+ + V +LLG G SLL
Sbjct: 62 SYEELVLSNKHVAPDHLLQICERI-------GPMLDKEIPPSISRVTSLLGAGRQSLLRT 114
Query: 168 DGDKVNEEVKPPPPYM----RWPHTKANQVHGLHLREIGGGLPRHHRAPSIRA-ACYAIA 222
D + K R P N +L EI HR + + ++ A
Sbjct: 115 AKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEI-------HRGKQLTGCSTFSTA 167
Query: 223 KPSTMVQKMQNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWSMETAYSLASCRGH 282
P TM Q ++ +RI GH +AVYC FDR+G + TGSDD LVKIWS L++ RGH
Sbjct: 168 FPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGH 227
Query: 283 VGDITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFSPRPNAVYQ 342
+I+D+AV+ N ++A+ S D IIRVW L P++VL+GHTG++T++ FSP +
Sbjct: 228 SAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQR 287
Query: 343 -LLSSSDDGTCRI--WDARYTHSTPR--LYVPKPSDSTGRSSGPSSNTMPQSHQIFCCAF 397
++S+ DGT WD +PR + KP Q+ C +F
Sbjct: 288 YMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGV---------------QMLCSSF 332
Query: 398 NANGTVFVTGSSDNLARVY 416
+ G TGS+D++ R+Y
Sbjct: 333 SVGGMFLATGSTDHVIRMY 351
Score = 48.5 bits (114), Expect = 3e-04
Identities = 35/141 (24%), Positives = 62/141 (43%), Gaps = 18/141 (12%)
Query: 232 QNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWSMET----AYSLASCRGHVGD-- 285
+ I + H + V F +G ++GS D +IW E + L GD
Sbjct: 359 EKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLS 418
Query: 286 ----------ITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFSP 335
+T +A + N+++V ++ ND++++VW G + L GH V + P
Sbjct: 419 SEEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHP 478
Query: 336 RPNAVYQLLSSSDDGTCRIWD 356
+ + +LS+ DG+ IWD
Sbjct: 479 FDSRI--MLSAGHDGSIFIWD 497
Score = 36.6 bits (83), Expect = 1.4
Identities = 17/68 (25%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Query: 246 CAIFDRSGRYVITGSDDRLVKIWSM--ETAYSLASCRGHVGDITDLAVSSNNALVASSSN 303
C+ F G ++ TGS D +++++ + E +A H + + +N S S
Sbjct: 329 CSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSR 388
Query: 304 DYIIRVWR 311
D R+WR
Sbjct: 389 DGTARIWR 396
>UniRef100_Q5R2V0 WD repeat protein WDR9-form2 [Homo sapiens]
Length = 2199
Score = 177 bits (450), Expect = 4e-43
Identities = 127/379 (33%), Positives = 186/379 (48%), Gaps = 54/379 (14%)
Query: 48 EVYFLIMRFLSAGPCHKTCSHLWNELLENQLLPRRYHAWYSRSGASSGVPHDDGQSFPLE 107
E+YFLI R+LSAGPC + L EL + QLLP+R W G H+
Sbjct: 17 ELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLD-W-------EGNEHN-------R 61
Query: 108 DYNKLAERYPHIEKDHLVKLLKQLLLNKASLSPGMSTGNPPNAADVPTLLGRGSFSLLSY 167
Y +L H+ DHL+++ +++ P + PP+ + V +LLG G SLL
Sbjct: 62 SYEELVLSNKHVAPDHLLQICERI-------GPMLDKEIPPSISRVTSLLGAGRQSLLRT 114
Query: 168 DGDKVNEEVKPPPPYM----RWPHTKANQVHGLHLREIGGGLPRHHRAPSIRA-ACYAIA 222
D + K R P N +L EI HR + + ++ A
Sbjct: 115 AKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEI-------HRGKQLTGCSTFSTA 167
Query: 223 KPSTMVQKMQNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWSMETAYSLASCRGH 282
P TM Q ++ +RI GH +AVYC FDR+G + TGSDD LVKIWS L++ RGH
Sbjct: 168 FPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGH 227
Query: 283 VGDITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFSPRPNAVYQ 342
+I+D+AV+ N ++A+ S D IIRVW L P++VL+GHTG++T++ FSP +
Sbjct: 228 SAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQR 287
Query: 343 -LLSSSDDGTCRI--WDARYTHSTPR--LYVPKPSDSTGRSSGPSSNTMPQSHQIFCCAF 397
++S+ DGT WD +PR + KP Q+ C +F
Sbjct: 288 YMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGV---------------QMLCSSF 332
Query: 398 NANGTVFVTGSSDNLARVY 416
+ G TGS+D++ R+Y
Sbjct: 333 SVGGMFLATGSTDHVIRMY 351
Score = 48.5 bits (114), Expect = 3e-04
Identities = 35/141 (24%), Positives = 62/141 (43%), Gaps = 18/141 (12%)
Query: 232 QNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWSMET----AYSLASCRGHVGD-- 285
+ I + H + V F +G ++GS D +IW E + L GD
Sbjct: 359 EKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLS 418
Query: 286 ----------ITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFSP 335
+T +A + N+++V ++ ND++++VW G + L GH V + P
Sbjct: 419 SEEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHP 478
Query: 336 RPNAVYQLLSSSDDGTCRIWD 356
+ + +LS+ DG+ IWD
Sbjct: 479 FDSRI--MLSAGHDGSIFIWD 497
Score = 36.6 bits (83), Expect = 1.4
Identities = 17/68 (25%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Query: 246 CAIFDRSGRYVITGSDDRLVKIWSM--ETAYSLASCRGHVGDITDLAVSSNNALVASSSN 303
C+ F G ++ TGS D +++++ + E +A H + + +N S S
Sbjct: 329 CSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSR 388
Query: 304 DYIIRVWR 311
D R+WR
Sbjct: 389 DGTARIWR 396
>UniRef100_Q96QH0 WDR9 protein, form A [Homo sapiens]
Length = 2320
Score = 177 bits (450), Expect = 4e-43
Identities = 127/379 (33%), Positives = 186/379 (48%), Gaps = 54/379 (14%)
Query: 48 EVYFLIMRFLSAGPCHKTCSHLWNELLENQLLPRRYHAWYSRSGASSGVPHDDGQSFPLE 107
E+YFLI R+LSAGPC + L EL + QLLP+R W G H+
Sbjct: 17 ELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLD-W-------EGNEHN-------R 61
Query: 108 DYNKLAERYPHIEKDHLVKLLKQLLLNKASLSPGMSTGNPPNAADVPTLLGRGSFSLLSY 167
Y +L H+ DHL+++ +++ P + PP+ + V +LLG G SLL
Sbjct: 62 SYEELVLSNKHVAPDHLLQICQRI-------GPMLDKEIPPSISRVTSLLGAGRQSLLRT 114
Query: 168 DGDKVNEEVKPPPPYM----RWPHTKANQVHGLHLREIGGGLPRHHRAPSIRA-ACYAIA 222
D + K R P N +L EI HR + + ++ A
Sbjct: 115 AKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEI-------HRGKQLTGCSTFSTA 167
Query: 223 KPSTMVQKMQNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWSMETAYSLASCRGH 282
P TM Q ++ +RI GH +AVYC FDR+G + TGSDD LVKIWS L++ RGH
Sbjct: 168 FPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGH 227
Query: 283 VGDITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFSPRPNAVYQ 342
+I+D+AV+ N ++A+ S D IIRVW L P++VL+GHTG++T++ FSP +
Sbjct: 228 SAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQR 287
Query: 343 -LLSSSDDGTCRI--WDARYTHSTPR--LYVPKPSDSTGRSSGPSSNTMPQSHQIFCCAF 397
++S+ DGT WD +PR + KP Q+ C +F
Sbjct: 288 YMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGV---------------QMLCSSF 332
Query: 398 NANGTVFVTGSSDNLARVY 416
+ G TGS+D++ R+Y
Sbjct: 333 SVGGMFLATGSTDHVIRMY 351
Score = 48.5 bits (114), Expect = 3e-04
Identities = 35/141 (24%), Positives = 62/141 (43%), Gaps = 18/141 (12%)
Query: 232 QNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWSMET----AYSLASCRGHVGD-- 285
+ I + H + V F +G ++GS D +IW E + L GD
Sbjct: 359 EKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLS 418
Query: 286 ----------ITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFSP 335
+T +A + N+++V ++ ND++++VW G + L GH V + P
Sbjct: 419 SEEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHP 478
Query: 336 RPNAVYQLLSSSDDGTCRIWD 356
+ + +LS+ DG+ IWD
Sbjct: 479 FDSRI--MLSAGHDGSIFIWD 497
Score = 36.6 bits (83), Expect = 1.4
Identities = 17/68 (25%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Query: 246 CAIFDRSGRYVITGSDDRLVKIWSM--ETAYSLASCRGHVGDITDLAVSSNNALVASSSN 303
C+ F G ++ TGS D +++++ + E +A H + + +N S S
Sbjct: 329 CSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSR 388
Query: 304 DYIIRVWR 311
D R+WR
Sbjct: 389 DGTARIWR 396
>UniRef100_Q96QG9 WDR9 protein, form B [Homo sapiens]
Length = 2269
Score = 177 bits (450), Expect = 4e-43
Identities = 127/379 (33%), Positives = 186/379 (48%), Gaps = 54/379 (14%)
Query: 48 EVYFLIMRFLSAGPCHKTCSHLWNELLENQLLPRRYHAWYSRSGASSGVPHDDGQSFPLE 107
E+YFLI R+LSAGPC + L EL + QLLP+R W G H+
Sbjct: 17 ELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLD-W-------EGNEHN-------R 61
Query: 108 DYNKLAERYPHIEKDHLVKLLKQLLLNKASLSPGMSTGNPPNAADVPTLLGRGSFSLLSY 167
Y +L H+ DHL+++ +++ P + PP+ + V +LLG G SLL
Sbjct: 62 SYEELVLSNKHVAPDHLLQICQRI-------GPMLDKEIPPSISRVTSLLGAGRQSLLRT 114
Query: 168 DGDKVNEEVKPPPPYM----RWPHTKANQVHGLHLREIGGGLPRHHRAPSIRA-ACYAIA 222
D + K R P N +L EI HR + + ++ A
Sbjct: 115 AKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEI-------HRGKQLTGCSTFSTA 167
Query: 223 KPSTMVQKMQNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWSMETAYSLASCRGH 282
P TM Q ++ +RI GH +AVYC FDR+G + TGSDD LVKIWS L++ RGH
Sbjct: 168 FPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGH 227
Query: 283 VGDITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFSPRPNAVYQ 342
+I+D+AV+ N ++A+ S D IIRVW L P++VL+GHTG++T++ FSP +
Sbjct: 228 SAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQR 287
Query: 343 -LLSSSDDGTCRI--WDARYTHSTPR--LYVPKPSDSTGRSSGPSSNTMPQSHQIFCCAF 397
++S+ DGT WD +PR + KP Q+ C +F
Sbjct: 288 YMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGV---------------QMLCSSF 332
Query: 398 NANGTVFVTGSSDNLARVY 416
+ G TGS+D++ R+Y
Sbjct: 333 SVGGMFLATGSTDHVIRMY 351
Score = 48.5 bits (114), Expect = 3e-04
Identities = 35/141 (24%), Positives = 62/141 (43%), Gaps = 18/141 (12%)
Query: 232 QNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWSMET----AYSLASCRGHVGD-- 285
+ I + H + V F +G ++GS D +IW E + L GD
Sbjct: 359 EKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLS 418
Query: 286 ----------ITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFSP 335
+T +A + N+++V ++ ND++++VW G + L GH V + P
Sbjct: 419 SEEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHP 478
Query: 336 RPNAVYQLLSSSDDGTCRIWD 356
+ + +LS+ DG+ IWD
Sbjct: 479 FDSRI--MLSAGHDGSIFIWD 497
Score = 36.6 bits (83), Expect = 1.4
Identities = 17/68 (25%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Query: 246 CAIFDRSGRYVITGSDDRLVKIWSM--ETAYSLASCRGHVGDITDLAVSSNNALVASSSN 303
C+ F G ++ TGS D +++++ + E +A H + + +N S S
Sbjct: 329 CSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSR 388
Query: 304 DYIIRVWR 311
D R+WR
Sbjct: 389 DGTARIWR 396
>UniRef100_Q9NSI6 WD-repeat protein 9 [Homo sapiens]
Length = 2269
Score = 177 bits (450), Expect = 4e-43
Identities = 127/379 (33%), Positives = 186/379 (48%), Gaps = 54/379 (14%)
Query: 48 EVYFLIMRFLSAGPCHKTCSHLWNELLENQLLPRRYHAWYSRSGASSGVPHDDGQSFPLE 107
E+YFLI R+LSAGPC + L EL + QLLP+R W G H+
Sbjct: 17 ELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLD-W-------EGNEHN-------R 61
Query: 108 DYNKLAERYPHIEKDHLVKLLKQLLLNKASLSPGMSTGNPPNAADVPTLLGRGSFSLLSY 167
Y +L H+ DHL+++ +++ P + PP+ + V +LLG G SLL
Sbjct: 62 SYEELVLSNKHVAPDHLLQICQRI-------GPMLDKEIPPSISRVTSLLGAGRQSLLRT 114
Query: 168 DGDKVNEEVKPPPPYM----RWPHTKANQVHGLHLREIGGGLPRHHRAPSIRA-ACYAIA 222
D + K R P N +L EI HR + + ++ A
Sbjct: 115 AKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEI-------HRGKQLTGCSTFSTA 167
Query: 223 KPSTMVQKMQNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWSMETAYSLASCRGH 282
P TM Q ++ +RI GH +AVYC FDR+G + TGSDD LVKIWS L++ RGH
Sbjct: 168 FPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGH 227
Query: 283 VGDITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFSPRPNAVYQ 342
+I+D+AV+ N ++A+ S D IIRVW L P++VL+GHTG++T++ FSP +
Sbjct: 228 SAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQR 287
Query: 343 -LLSSSDDGTCRI--WDARYTHSTPR--LYVPKPSDSTGRSSGPSSNTMPQSHQIFCCAF 397
++S+ DGT WD +PR + KP Q+ C +F
Sbjct: 288 YMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGV---------------QMLCSSF 332
Query: 398 NANGTVFVTGSSDNLARVY 416
+ G TGS+D++ R+Y
Sbjct: 333 SVGGMFLATGSTDHVIRMY 351
Score = 48.5 bits (114), Expect = 3e-04
Identities = 35/141 (24%), Positives = 62/141 (43%), Gaps = 18/141 (12%)
Query: 232 QNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWSMET----AYSLASCRGHVGD-- 285
+ I + H + V F +G ++GS D +IW E + L GD
Sbjct: 359 EKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLS 418
Query: 286 ----------ITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFSP 335
+T +A + N+++V ++ ND++++VW G + L GH V + P
Sbjct: 419 SEEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHP 478
Query: 336 RPNAVYQLLSSSDDGTCRIWD 356
+ + +LS+ DG+ IWD
Sbjct: 479 FDSRI--MLSAGHDGSIFIWD 497
Score = 36.6 bits (83), Expect = 1.4
Identities = 17/68 (25%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Query: 246 CAIFDRSGRYVITGSDDRLVKIWSM--ETAYSLASCRGHVGDITDLAVSSNNALVASSSN 303
C+ F G ++ TGS D +++++ + E +A H + + +N S S
Sbjct: 329 CSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSR 388
Query: 304 DYIIRVWR 311
D R+WR
Sbjct: 389 DGTARIWR 396
>UniRef100_UPI00003A9CE5 UPI00003A9CE5 UniRef100 entry
Length = 1380
Score = 176 bits (445), Expect = 1e-42
Identities = 124/384 (32%), Positives = 183/384 (47%), Gaps = 64/384 (16%)
Query: 48 EVYFLIMRFLSAGPCHKTCSHLWNELLENQLLPRRYHAWYSRSGASSGVPHDDGQSFPLE 107
E+YFLI RFLS GPC T L EL ++QLLP+R W G H
Sbjct: 2 ELYFLIARFLSTGPCRGTLRVLVQELEQHQLLPKRLD-W-------EGNEH-------YR 46
Query: 108 DYNKLAERYPHIEKDHLVKLLKQLLLNKASLSPGMSTGNPPNAADVPTLLGRGSFSLLSY 167
Y +L H+ DHL+++ K++ P + PP+ + V +LLG G SLL
Sbjct: 47 SYEELVLSNKHVAPDHLLQICKRI-------GPILDKEIPPSISRVNSLLGAGRQSLLRT 99
Query: 168 DGDKVNEEVKP----------PPPYMRWPHTKANQVHGLHLREIGGGLPRHHRAPSIRAA 217
D N K PP + T N V R++ G A
Sbjct: 100 AKDCRNTVWKGSAFAALHRGRPPEFPVNYGTPPNLVEVYRARQLTG------------YA 147
Query: 218 CYAIAKPSTMVQKMQNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWSMETAYSLA 277
++ + P +M Q ++ +RI GH ++VYC FDR+G + TGSDD LVKIWS A
Sbjct: 148 KFSTSFPGSMYQHVKMHRRILGHLSSVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLFA 207
Query: 278 SCRGHVGDITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFSPR- 336
+ RGH +I+D+AV+ N ++A+ S D +IRVW L P++VL GHTG++T++ FSP
Sbjct: 208 TLRGHSAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPVAVLHGHTGSITSLQFSPMV 267
Query: 337 PNAVYQLLSSSDDGTCRIW----DARYTHSTPRLYVPKPSDSTGRSSGPSSNTMPQSHQI 392
++ ++S+ DG W D+ + P + KP Q+
Sbjct: 268 KGSLRYMVSTGADGNVCFWQWDTDSMKFSNRPVKFTEKPRPGV---------------QM 312
Query: 393 FCCAFNANGTVFVTGSSDNLARVY 416
C +F+ G TGS+D++ R+Y
Sbjct: 313 LCSSFSVGGMFLATGSTDHVIRMY 336
Score = 45.4 bits (106), Expect = 0.003
Identities = 36/141 (25%), Positives = 59/141 (41%), Gaps = 18/141 (12%)
Query: 232 QNIKRIRGHCNAVYCAIFDRSGRYVITGSDDRLVKIWSMETA----YSLASCRGHVGD-- 285
+ I + H + V F SG I+GS D +IW E A L GD
Sbjct: 344 ERIAELESHADKVDSIQFSNSGDRFISGSRDGTARIWRFEEAEWRSILLDMSDRLPGDMC 403
Query: 286 ----------ITDLAVSSNNALVASSSNDYIIRVWRLPDGLPISVLRGHTGAVTAIAFSP 335
+T +A + ++ V ++ N+++++VW G + L GH V + P
Sbjct: 404 SDEDKFMRPKVTMIAWNQDDNYVVTAVNNHLLKVWNSSTGQLLHDLVGHADEVFVLETHP 463
Query: 336 RPNAVYQLLSSSDDGTCRIWD 356
+ + +LS+ DG IWD
Sbjct: 464 FDSRI--MLSAGHDGNIFIWD 482
Score = 38.5 bits (88), Expect = 0.36
Identities = 20/78 (25%), Positives = 36/78 (45%), Gaps = 2/78 (2%)
Query: 246 CAIFDRSGRYVITGSDDRLVKIW--SMETAYSLASCRGHVGDITDLAVSSNNALVASSSN 303
C+ F G ++ TGS D +++++ ET +A H + + S++ S S
Sbjct: 314 CSSFSVGGMFLATGSTDHVIRMYYFGSETPERIAELESHADKVDSIQFSNSGDRFISGSR 373
Query: 304 DYIIRVWRLPDGLPISVL 321
D R+WR + S+L
Sbjct: 374 DGTARIWRFEEAEWRSIL 391
Score = 35.0 bits (79), Expect = 3.9
Identities = 23/93 (24%), Positives = 45/93 (47%), Gaps = 6/93 (6%)
Query: 249 FDRSGRYVITGSDDRLVKIWSMETAYSLASCRGHVGDITDLAVSS-NNALVASSSNDYII 307
+++ YV+T ++ L+K+W+ T L GH ++ L ++ ++ S+ +D I
Sbjct: 419 WNQDDNYVVTAVNNHLLKVWNSSTGQLLHDLVGHADEVFVLETHPFDSRIMLSAGHDGNI 478
Query: 308 RVWRLPDGLP----ISVLRGH-TGAVTAIAFSP 335
+W + G +++ G GAV FSP
Sbjct: 479 FIWDITKGTKTKHYFNMIEGQGHGAVFDCKFSP 511
Database: uniref100
Posted date: Jan 5, 2005 1:24 AM
Number of letters in database: 848,049,833
Number of sequences in database: 2,790,947
Lambda K H
0.318 0.134 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 758,943,621
Number of Sequences: 2790947
Number of extensions: 33468478
Number of successful extensions: 112069
Number of sequences better than 10.0: 4809
Number of HSP's better than 10.0 without gapping: 2596
Number of HSP's successfully gapped in prelim test: 2287
Number of HSP's that attempted gapping in prelim test: 82069
Number of HSP's gapped (non-prelim): 19875
length of query: 417
length of database: 848,049,833
effective HSP length: 130
effective length of query: 287
effective length of database: 485,226,723
effective search space: 139260069501
effective search space used: 139260069501
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 76 (33.9 bits)
Medicago: description of AC144539.12