BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC144431.4 - phase: 0 /pseudo
         (1510 letters)

Database: uniref100 
           2,790,947 sequences; 848,049,833 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

UniRef100_Q9FHA3 DNA polymerase alpha 1 [Arabidopsis thaliana]       1545  0.0
UniRef100_O48653 DNA polymerase alpha catalytic subunit [Oryza s...  1468  0.0
UniRef100_Q8S1N7 Putative DNA polymerase alpha catalytic subunit...  1422  0.0
UniRef100_Q9DE46 DNA polymerase alpha catalytic subunit [Xenopus...   692  0.0
UniRef100_UPI00003A9D8C UPI00003A9D8C UniRef100 entry                 691  0.0
UniRef100_UPI00003A9D8B UPI00003A9D8B UniRef100 entry                 691  0.0
UniRef100_UPI00003A9D8E UPI00003A9D8E UniRef100 entry                 686  0.0
UniRef100_UPI00003C2140 UPI00003C2140 UniRef100 entry                 686  0.0
UniRef100_Q86UQ7 Polymerase (DNA directed), alpha [Homo sapiens]      685  0.0
UniRef100_P09884 DNA polymerase alpha catalytic subunit [Homo sa...   685  0.0
UniRef100_O89042 DNA polymerase alpha catalytic subunit [Rattus ...   672  0.0
UniRef100_UPI000035F163 UPI000035F163 UniRef100 entry                 662  0.0
UniRef100_Q7ZA56 DNA polymerase alpha catalytic subunit [Coprinu...   662  0.0
UniRef100_Q6DRM6 DNA polymerase alpha [Brachydanio rerio]             661  0.0
UniRef100_Q7Z081 DNA polymerase catalytic subunit alpha [Stylony...   650  0.0
UniRef100_Q7Z083 DNA polymerase catalytic subunit alpha [Stylony...   649  0.0
UniRef100_Q7Z080 DNA polymerase catalytic subunit alpha [Stylony...   649  0.0
UniRef100_Q7Z084 DNA polymerase catalytic subunit alpha [Stylony...   648  0.0
UniRef100_Q7Z078 DNA polymerase catalytic subunit alpha [Stylony...   647  0.0
UniRef100_Q7Z082 DNA polymerase catalytic subunit alpha [Stylony...   645  0.0

>UniRef100_Q9FHA3 DNA polymerase alpha 1 [Arabidopsis thaliana]
          Length = 1492

 Score = 1545 bits (3999), Expect = 0.0
 Identities = 771/1131 (68%), Positives = 925/1131 (81%), Gaps = 11/1131 (0%)

Query: 382  VWQGTLYQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQDAV 441
            V  G  Y+SCCVVVKN+QRCVYAIP+  +  ++E+I LE++V++SR+SP  FR KL +  
Sbjct: 370  VKMGDTYKSCCVVVKNIQRCVYAIPNDSIFPSHELIMLEQEVKDSRLSPESFRGKLHEMA 429

Query: 442  SDTKNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKG 501
            S  KNEIA+ L+ L VS+FSMAPVKR YAFER D+PAGE YV+KINY FKD  LP DLKG
Sbjct: 430  SKLKNEIAQELLQLNVSNFSMAPVKRNYAFERPDVPAGEQYVLKINYSFKDRPLPEDLKG 489

Query: 502  KSFCALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRA 561
            +SF ALLG+  SALE F++KRKI GP WL++S+FSTCS S+ VSWCKFEV V SPKDI  
Sbjct: 490  ESFSALLGSHTSALEHFILKRKIMGPCWLKISSFSTCSPSEGVSWCKFEVTVQSPKDITI 549

Query: 562  SSPSSSKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRP 621
                 S+  +V+PP VVTAINLKT +NEKQNI+EIVSASV+  +  KID PM A E KR 
Sbjct: 550  LV---SEEKVVHPPAVVTAINLKTIVNEKQNISEIVSASVLCFHNAKIDVPMPAPERKRS 606

Query: 622  GMLTHFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSD 681
            G+L+HFTV+R  +G  +P+G+  EV+DRN K G NVL +E+SERALLNRL L+L+K+DSD
Sbjct: 607  GILSHFTVVRNPEGTGYPIGWKKEVSDRNSKNGCNVLSIENSERALLNRLFLELNKLDSD 666

Query: 682  VLVGHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMS 741
            +LVGHNISGFDLDVLL R+QAC+V SSMWSK+GRL RS MPKL +    +G GA P +MS
Sbjct: 667  ILVGHNISGFDLDVLLQRAQACKVQSSMWSKIGRLKRSFMPKL-KGNSNYGSGATPGLMS 725

Query: 742  CVAGRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMELIE 801
            C+AGRLLCDT LCSRDLLKEVSYSLT L+KTQLN+ RKE+AP+++PKMFQ++K+L+ELIE
Sbjct: 726  CIAGRLLCDTDLCSRDLLKEVSYSLTDLSKTQLNRDRKEIAPNDIPKMFQSSKTLVELIE 785

Query: 802  YGETDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIV 861
             GETDAWLSMELMF+LSVLPLT QLTN+SGNLWGKTLQGARAQR+EY LLH FH KK+I+
Sbjct: 786  CGETDAWLSMELMFHLSVLPLTLQLTNISGNLWGKTLQGARAQRIEYYLLHTFHSKKFIL 845

Query: 862  PDKFSNYAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNKKAASYAGGLV 921
            PDK S   KE K +KRR+ +  +D N D+ D  D    ND S+    K KK  +YAGGLV
Sbjct: 846  PDKISQRMKEIKSSKRRMDYAPEDRNVDELDA-DLTLENDPSKGS--KTKKGPAYAGGLV 902

Query: 922  LEPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSSDDSFPRLPSSKTTGVLPELLK 981
            LEPK+GLYDKY+LLLDFNSLYPSIIQEYNICFTT+ RS +D  PRLPSS+T G+LP+L++
Sbjct: 903  LEPKRGLYDKYVLLLDFNSLYPSIIQEYNICFTTIPRS-EDGVPRLPSSQTPGILPKLME 961

Query: 982  KLVKLRREKKTWMKTASGLKRQQLDIEQQALKLTANSMYGCLGFSNSRFYAKPLAELITL 1041
             LV +R+  K  MK  +GLK  +LDI QQALKLTANSMYGCLGFSNSRFYAKPLAELITL
Sbjct: 962  HLVSIRKSVKLKMKKETGLKYWELDIRQQALKLTANSMYGCLGFSNSRFYAKPLAELITL 1021

Query: 1042 QGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEVNKKYRCLE 1101
            QGR+ILQ TVDLVQN+LNLEVIYGDTDSIMI+SGLDDI +  +I  KVIQEVNKKYRCL+
Sbjct: 1022 QGRDILQRTVDLVQNHLNLEVIYGDTDSIMIHSGLDDIEEVKAIKSKVIQEVNKKYRCLK 1081

Query: 1102 IDLDGLYKRMLLLKKKKYAAVKVQFKDGTPYEVIERKGLDIVRRDWSLLAKDLGDFCLTQ 1161
            ID DG+YKRMLLL+KKKYAAVK+QFKDG P E IERKG+D+VRRDWSLL+K++GD CL++
Sbjct: 1082 IDCDGIYKRMLLLRKKKYAAVKLQFKDGKPCEDIERKGVDMVRRDWSLLSKEIGDLCLSK 1141

Query: 1162 ILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDAKNQPHVLVA 1221
            IL GGSCEDVVE+IHN LMK++EEMRNGQVALEKYVITKTLTKPP AYPD+K+QPHV VA
Sbjct: 1142 ILYGGSCEDVVEAIHNELMKIKEEMRNGQVALEKYVITKTLTKPPAAYPDSKSQPHVQVA 1201

Query: 1222 QRLKQQGYTSGCSVGDTIPYVICCEQG-GSSGSATGIALRARHPDELKQEQGTWLIDIDY 1280
             R++Q+GY  G +  DT+PY+IC EQG  SS S+ GIA RARHPDE+K E   WL+DIDY
Sbjct: 1202 LRMRQRGYKEGFNAKDTVPYIICYEQGNASSASSAGIAERARHPDEVKSEGSRWLVDIDY 1261

Query: 1281 YLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQHKSSEA-SDDPTSSLLFAGDDEE 1339
            YL+QQIHPV+SRLCA IQGTSPERLA+CLGLD SK++ KS++A S DP++SLLFA  DEE
Sbjct: 1262 YLAQQIHPVVSRLCAEIQGTSPERLAECLGLDPSKYRSKSNDATSSDPSTSLLFATSDEE 1321

Query: 1340 SEKPTSSGTDESDYNFWRKLCCPKC-FENGAGRISAAMIANQVKRQAEKFVLMYYRGLLM 1398
            S+KP +  T+ESD  FW KL CPKC  E+  G IS AMIANQVKRQ + FV MYY+G+++
Sbjct: 1322 SKKPATPETEESDSTFWLKLHCPKCQQEDSTGIISPAMIANQVKRQIDGFVSMYYKGIMV 1381

Query: 1399 CDDETCKHTTRSVSFRLVGDSERGTVCPNYPRCNGHLNRKYTEADLYKQLSYFCHVFDTV 1458
            C+DE+CKHTTRS +FRL+G+ ERGTVCPNYP CNG L RKYTEADLYKQLSYFCH+ DT 
Sbjct: 1382 CEDESCKHTTRSPNFRLLGERERGTVCPNYPNCNGTLLRKYTEADLYKQLSYFCHILDTQ 1441

Query: 1459 CYIEKMEAKSRIPIEKELIKIRPIVDLAASTIQKIRDRCAFGWVKLQDLVV 1509
            C +EKM+   RI +EK + KIRP V  AA+  +  RDRCA+GW++L D+V+
Sbjct: 1442 CSLEKMDVGVRIQVEKAMTKIRPAVKSAAAITRSSRDRCAYGWMQLTDIVI 1492



 Score = 53.9 bits (128), Expect = 4e-05
 Identities = 28/69 (40%), Positives = 44/69 (63%), Gaps = 2/69 (2%)

Query: 1  MADDDGSSRKRRPTRGPDATARSQALELLRSRRSNGPRSTTTP--QIRLENPIYDTIPED 58
          M+ D+ +   RR +RG +A++R   LE L++ R  G RS +     IRL+ PI+DT+ ++
Sbjct: 1  MSGDNSTETGRRRSRGAEASSRKDTLERLKAIRQGGIRSASGGGYDIRLQKPIFDTVDDE 60

Query: 59 EYTALVASR 67
          EY ALV+ R
Sbjct: 61 EYDALVSRR 69


>UniRef100_O48653 DNA polymerase alpha catalytic subunit [Oryza sativa]
          Length = 1243

 Score = 1468 bits (3801), Expect = 0.0
 Identities = 746/1169 (63%), Positives = 915/1169 (77%), Gaps = 55/1169 (4%)

Query: 385  GTLYQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQDAVSDT 444
            G  + SCCVVVKNMQRC+YAIPS  +   + + +LEK+   S  SP+  R  L +  S  
Sbjct: 86   GKRFHSCCVVVKNMQRCIYAIPSSSIFPRDTISRLEKNSTTSDSSPS-LRASLHELASGL 144

Query: 445  KNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSF 504
            K+EIA  L D  VS+F+M PVKR YAFERTD+P GE YV+KINY +KD+ALP DL+G+ F
Sbjct: 145  KSEIADKLSDFNVSNFAMTPVKRNYAFERTDLPNGEQYVLKINYPYKDSALPTDLRGQHF 204

Query: 505  CALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSP 564
             ALLG  NSALEL LIKRKIKGPSWL +S F  C A+QRVSWCKFEV VDSPKDI     
Sbjct: 205  HALLGTNNSALELLLIKRKIKGPSWLSISKFLACPATQRVSWCKFEVTVDSPKDISVLMT 264

Query: 565  SSSKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGML 624
            S+   TL  PPVVV A+NLKT INEK N++EIVSASV+ C+ VKID+PM + +W++ GML
Sbjct: 265  ST---TLEVPPVVVAAVNLKTIINEKHNVHEIVSASVICCHRVKIDSPMRSEDWQKRGML 321

Query: 625  THFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSDVLV 684
            +HFTV+RKL+G+IFP+G + E +DRN KAGSNVL +ESSERALLNRLM++L K+D DVLV
Sbjct: 322  SHFTVMRKLEGSIFPIGLSKESSDRNQKAGSNVLALESSERALLNRLMIELSKLDCDVLV 381

Query: 685  GHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMSCVA 744
            GHNISGFDLDVLLHR+Q C+VPS+MWSK+GRL RS MP+L +    +G GA P IMSC+A
Sbjct: 382  GHNISGFDLDVLLHRAQTCKVPSNMWSKIGRLRRSVMPRLTKGNTLYGSGASPGIMSCIA 441

Query: 745  GRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMELIEYGE 804
            GRLLCDTYLCSRDLLKEVSYSLT LA+TQL + RKEV+PH++P MFQ++ +L++L+EYGE
Sbjct: 442  GRLLCDTYLCSRDLLKEVSYSLTQLAETQLKKERKEVSPHDIPPMFQSSGALLKLVEYGE 501

Query: 805  TDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIVPDK 864
            TDA L++ELMF+LSVLPLTRQLTN+SGNLWGKTLQG+RAQRVEYLLLH FH +K+IVPDK
Sbjct: 502  TDACLALELMFHLSVLPLTRQLTNISGNLWGKTLQGSRAQRVEYLLLHAFHARKFIVPDK 561

Query: 865  FSNYAKETKLTKRRVTHGVDDGNFDDAD--INDANYHNDASESDHKKNKKAASYAGGLVL 922
            F+  +KE   TKR++    +    D+AD  I+D  +H      D  K KK  SYAGGLVL
Sbjct: 562  FAR-SKEFNSTKRKMNPDTEAARPDEADPSIDDEGHH-----VDQGKTKKGPSYAGGLVL 615

Query: 923  EPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSSDDSFPRLPSSKTTGVLPELLKK 982
            EPKKGLYDKY+LLLDFNSLYPSIIQEYNICFTTV+RS+D + P LP+SKTTGVLPELLK 
Sbjct: 616  EPKKGLYDKYVLLLDFNSLYPSIIQEYNICFTTVDRSADGNVPNLPASKTTGVLPELLKS 675

Query: 983  LVKLRREKKTWMKTASGLKRQQLDIEQQALKLTANSMYGCLGFSNSRFYAKPLAELITLQ 1042
            LV+ RR  K+W+KTASGLKRQQ DI+QQALKLTANSMYGCLGFSNSRFYAKPLAELITLQ
Sbjct: 676  LVERRRMVKSWLKTASGLKRQQFDIQQQALKLTANSMYGCLGFSNSRFYAKPLAELITLQ 735

Query: 1043 GREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEVNKKYRCLEI 1102
            GREILQ+TVDLVQNNLNLEVIYGDTDSIMI++GLDDI++A  I+ KVIQEVNKKYRCLEI
Sbjct: 736  GREILQNTVDLVQNNLNLEVIYGDTDSIMIHTGLDDISRAKGIAGKVIQEVNKKYRCLEI 795

Query: 1103 DLDGLYKRMLLLKKKKYAAVKVQFKDGTPYEVIERKGLDIVRRDWSLLAKDLGDFCLTQI 1162
            DLDG+YKRMLLLKKKKYAA+KV   DG+  E IERKGLD+VRRDWSLL+K++GDFCL QI
Sbjct: 796  DLDGIYKRMLLLKKKKYAAIKVAL-DGSLRENIERKGLDMVRRDWSLLSKEIGDFCLNQI 854

Query: 1163 LSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDAKNQPHVLVAQ 1222
            LSGGSC+DV+ESIH+SL++VQE+MR GQ  LEKY+ITK+LTK PE YPDAKNQPHV VA 
Sbjct: 855  LSGGSCDDVIESIHSSLVQVQEQMRGGQTELEKYIITKSLTKAPEDYPDAKNQPHVQVAL 914

Query: 1223 RLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGI-ALRARHPDELKQEQGTWL---IDI 1278
            RLKQ GY SGCS GDT+PY+IC +Q   S  +  I + RA+   E  +   T +   I  
Sbjct: 915  RLKQNGY-SGCSAGDTVPYIICSQQDSESTHSERIDSQRAQREPEGWKNLYTMVCLRILA 973

Query: 1279 DYYLSQQIHPVISRLCASI-QGTSPERLADCLGLDTSKFQHKSSEASDDPTSSLLFAGDD 1337
             YYL Q+I+PV+SR+CA++ +GT P RLA+CLGLD+SKFQ + +E+ +  TSS+L +  D
Sbjct: 974  SYYLQQRINPVVSRVCAAVSRGTEPARLAECLGLDSSKFQSRLTESDNQDTSSMLLSVID 1033

Query: 1338 EESEK-----------PTSSGT------------------------DESDYNFWRKLCCP 1362
            +E E+           P+ S T                        +++  NFWR++ CP
Sbjct: 1034 DEDERYRGCEPLRLSCPSCSTTFDCPPVSSLIIGSSSGNVSNPNEGNDASINFWRRMRCP 1093

Query: 1363 KC-FENGAGRISAAMIANQVKRQAEKFVLMYYRGLLMCDDETCKHTTRSVSFRLVGDSER 1421
            +C  +    R+S A++ANQ+KRQA+ F+ +YY+GLLMCDDE CK++T SV+ R++GDSER
Sbjct: 1094 RCPDDTDESRVSPAVLANQMKRQADSFINLYYKGLLMCDDEGCKYSTHSVNLRVMGDSER 1153

Query: 1422 GTVCPNYPRCNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKMEAKSRIPIEKELIKIRP 1481
            GT+CPNYPRCNGHL R+YTEADLY+QLSYFC+V D    +EK++ K+R+P EKE   +  
Sbjct: 1154 GTICPNYPRCNGHLVRQYTEADLYRQLSYFCYVVDATRCLEKLDQKARLPFEKEFAALSQ 1213

Query: 1482 IVDLAASTIQKIRDRCAFGWVKLQDLVVA 1510
             ++LA   +QKIRDRCAFGWV+L+DL ++
Sbjct: 1214 TINLALMEVQKIRDRCAFGWVQLKDLAIS 1242


>UniRef100_Q8S1N7 Putative DNA polymerase alpha catalytic subunit [Oryza sativa]
          Length = 1637

 Score = 1422 bits (3682), Expect = 0.0
 Identities = 753/1280 (58%), Positives = 913/1280 (70%), Gaps = 179/1280 (13%)

Query: 385  GTLYQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQDAVSDT 444
            G  + SCCVVVKNMQRC+YAIPS  +   + + +LEK+   S  SP+  R  L +  S  
Sbjct: 382  GKRFHSCCVVVKNMQRCIYAIPSSSIFPRDTISRLEKNSTTSDSSPS-LRASLHELASGL 440

Query: 445  KNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSF 504
            K+EIA  L D  VS+F+M PVKR YAFERTD+P GE YV+KINY +KD ALP DL+G+ F
Sbjct: 441  KSEIADKLSDFNVSNFAMTPVKRNYAFERTDLPNGEQYVLKINYPYKDPALPTDLRGQHF 500

Query: 505  CALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSP 564
             ALLG  NSALEL LIKRKIKGPSWL +S F  C A+QRVSWCKFEV VDSPKDI     
Sbjct: 501  HALLGTNNSALELLLIKRKIKGPSWLSISKFLACPATQRVSWCKFEVTVDSPKDISVLMT 560

Query: 565  SSSKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGML 624
            S+   TL  PPVVV A+NLKT INEK N++EIVSASV+ C+ VKID+PM + +W++ GML
Sbjct: 561  ST---TLEVPPVVVAAVNLKTIINEKHNVHEIVSASVICCHRVKIDSPMRSEDWQKRGML 617

Query: 625  THFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSDVLV 684
            +HFTV+RKL+G+IFP+G + E +DRN KAGSNVL +ESSERALLNRLM++L K+D DVLV
Sbjct: 618  SHFTVMRKLEGSIFPIGLSKESSDRNQKAGSNVLALESSERALLNRLMIELSKLDCDVLV 677

Query: 685  GHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMSCVA 744
            GHNISGFDLDVLLHR+Q C+VPS+MWSK+GRL RS MP+L +    +G GA P IMSC+A
Sbjct: 678  GHNISGFDLDVLLHRAQTCKVPSNMWSKIGRLRRSVMPRLTKGNTLYGSGASPGIMSCIA 737

Query: 745  GRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMELIEYGE 804
            GRLLCDTYLCSRDLLKEVSYSLT LA+TQL + RKEV+PH++P MFQ++ +L++L+EYGE
Sbjct: 738  GRLLCDTYLCSRDLLKEVSYSLTQLAETQLKKERKEVSPHDIPPMFQSSGALLKLVEYGE 797

Query: 805  TDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIVPDK 864
            TDA L++ELMF+LSVLPLTRQLTN+SGNLWGKTLQG+RAQRVEYLLLH FH +K+IVPDK
Sbjct: 798  TDACLALELMFHLSVLPLTRQLTNISGNLWGKTLQGSRAQRVEYLLLHAFHARKFIVPDK 857

Query: 865  FSNYAKETKLTKRRVTHGVDDGNFDDAD--INDANYHNDASESDHKKNKKAASYAGGLVL 922
            F+  +KE   TKR++    +    D+AD  I+D  +H D       K KK  SYAGGLVL
Sbjct: 858  FAR-SKEFNSTKRKMNPDTEAARPDEADPSIDDEGHHVDQG-----KTKKGPSYAGGLVL 911

Query: 923  EPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSSDDSFPRLPSSKTTGVLPE---- 978
            EPKKGLYDKY+LLLDFNSLYPSIIQEYNICFTTV+RS+D + P LP+SKTTGVLPE    
Sbjct: 912  EPKKGLYDKYVLLLDFNSLYPSIIQEYNICFTTVDRSADGNVPNLPASKTTGVLPESFNN 971

Query: 979  ------------------------------------LLKKLVKLRREKKTWMKTASGLKR 1002
                                                LLK LV+ RR  K+W+KTASGLKR
Sbjct: 972  LVLHGFLTAMRNLGFGLDCGDMISVGLLMRGFLMIKLLKSLVERRRMVKSWLKTASGLKR 1031

Query: 1003 QQLDIEQQALKLTANSMYGCLGFSNSRFYAKPLAELITLQGREILQSTVDLVQNNLNLEV 1062
            QQ DI+QQALKLTAN           RFYAKPLAELITLQGREILQ+TVDLVQNNLNLEV
Sbjct: 1032 QQFDIQQQALKLTAN-----------RFYAKPLAELITLQGREILQNTVDLVQNNLNLEV 1080

Query: 1063 IYGDTDSIMIYSGLDDIAKATSISKKVIQE------------------VNKKYRCL---- 1100
            IYGDTDSIMI++GLDDI++A  I+ KVIQE                  VNKKYRCL    
Sbjct: 1081 IYGDTDSIMIHTGLDDISRAKGIAGKVIQERDSMHSGERPVNISALMQVNKKYRCLEIDL 1140

Query: 1101 ------------------------------------------------------EIDLDG 1106
                                                                  EIDLDG
Sbjct: 1141 DGIYKRMLLLKKKKYAAIKVALDGSLRERDSMHSGERPVNISALMQVNKKYRCLEIDLDG 1200

Query: 1107 LYKRMLLLKKKKYAAVKVQFKDGTPYEV-------------------------IERKGLD 1141
            +YKRMLLLKKKKYAA+KV   DG+  EV                         IERKGLD
Sbjct: 1201 IYKRMLLLKKKKYAAIKVAL-DGSLREVCGCSDFQNYILSSKTGIIKECLMQNIERKGLD 1259

Query: 1142 IVRRDWSLLAKDLGDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKT 1201
            +VRRDWSLL+K++GDFCL QILSGGSC+DV+ESIH+SL++VQE+MR GQ  LEKY+ITK+
Sbjct: 1260 MVRRDWSLLSKEIGDFCLNQILSGGSCDDVIESIHSSLVQVQEQMRGGQTELEKYIITKS 1319

Query: 1202 LTKPPEAYPDAKNQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRA 1261
            LTK PE YPDAKNQPH  VA RLKQ GY SGCS GDT+PY+IC +Q   S  + GIA RA
Sbjct: 1320 LTKAPEDYPDAKNQPH--VALRLKQNGY-SGCSAGDTVPYIICSQQDSESTHSGGIAQRA 1376

Query: 1262 RHPDELKQEQGTWLIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQHKSS 1321
            RHP+ELK+    W+IDIDYYLSQQIHPV+SRLCASIQGTSP RLA+CLGLD+SKFQ + +
Sbjct: 1377 RHPEELKRNPDKWMIDIDYYLSQQIHPVVSRLCASIQGTSPARLAECLGLDSSKFQSRLT 1436

Query: 1322 EASDDPTSSLLFAGDDEESEK---PTSSGT-------DESDYNFWRKLCCPKC-FENGAG 1370
            E+ +  TSS+L +  D+E E     +SSG        +++  NFWR++ CP+C  +    
Sbjct: 1437 ESDNQDTSSMLLSVIDDEDESLIIGSSSGNVSNPNEGNDASINFWRRMRCPRCPDDTDES 1496

Query: 1371 RISAAMIANQVKRQAEKFVLMYYRGLLMCDDETCKHTTRSVSFRLVGDSERGTVCPNYPR 1430
            R+S A++ANQ+KRQA+ F+ +YY+GLLMCDDE CK++T SV+ R++GDSERGT+CPNYPR
Sbjct: 1497 RVSPAVLANQMKRQADSFINLYYKGLLMCDDEGCKYSTHSVNLRVMGDSERGTICPNYPR 1556

Query: 1431 CNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKMEAKSRIPIEKELIKIRPIVDLAASTI 1490
            CNGHL R+YTEADLY+QLSYFC+V D    +EK++ K+R+P EKE   +   ++LA   +
Sbjct: 1557 CNGHLVRQYTEADLYRQLSYFCYVVDATRCLEKLDQKARLPFEKEFAALSQTINLALMEV 1616

Query: 1491 QKIRDRCAFGWVKLQDLVVA 1510
            QKIRDRCAFGWV+L+DL ++
Sbjct: 1617 QKIRDRCAFGWVQLKDLAIS 1636



 Score = 67.0 bits (162), Expect = 4e-09
 Identities = 33/64 (51%), Positives = 43/64 (66%)

Query: 4  DDGSSRKRRPTRGPDATARSQALELLRSRRSNGPRSTTTPQIRLENPIYDTIPEDEYTAL 63
          D G+S +R   RG +A ARS ALE LR+ R  G R+    Q+R+E PIYDT+ E++Y AL
Sbjct: 7  DAGASGRRSRARGSEAVARSAALERLRAIRDGGARAAAAVQVRIEAPIYDTVAEEDYAAL 66

Query: 64 VASR 67
          VA R
Sbjct: 67 VARR 70


>UniRef100_Q9DE46 DNA polymerase alpha catalytic subunit [Xenopus laevis]
          Length = 1458

 Score =  692 bits (1785), Expect = 0.0
 Identities = 455/1166 (39%), Positives = 631/1166 (54%), Gaps = 134/1166 (11%)

Query: 388  YQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQDAVSDTKNE 447
            Y SCCV VKN++R VY +P          +   KD   + +S     ++  +AV++ K +
Sbjct: 373  YVSCCVSVKNIERTVYLLP----RENRVQLSTGKDTG-APVSMMHVYQEFNEAVAE-KYK 426

Query: 448  IAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSFCAL 507
            I K         F    V + YAFE  D+PA   Y+ ++ Y      LP DLKG++F  +
Sbjct: 427  IMK---------FKSKKVDKDYAFEIPDVPASSEYL-EVRYSADSPQLPQDLKGETFSHV 476

Query: 508  LGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSPSSS 567
             G   S+LELFL+ RKIKGPSWL++   S   +SQ +SWCK E +V  P  +        
Sbjct: 477  FGTNTSSLELFLLSRKIKGPSWLEIK--SPQLSSQPMSWCKVEAVVTRPDQVSVVKD--- 531

Query: 568  KITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGMLTHF 627
               L  PPVVV ++++KT  N K + NEIV+ + +  +   +D         +P   THF
Sbjct: 532  ---LAPPPVVVLSLSMKTVQNAKTHQNEIVAIAALVHHTFPLDKAP-----PQPPFQTHF 583

Query: 628  TVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSDVLVGHN 687
             V+ KL+  IFP  +N  V  +N       + +  +ER LL   + ++HK+D DV+VGH+
Sbjct: 584  CVLSKLNDCIFPYDYNEAVKQKNAN-----IEIALTERTLLGFFLAKIHKIDPDVIVGHD 638

Query: 688  ISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMSCVAGRL 747
            I GFDL+VLL R  +C+VP   WSK+GRL RS MPKL  R    GF    A  +   GR+
Sbjct: 639  IYGFDLEVLLQRINSCKVP--FWSKIGRLRRSVMPKLGGRS---GF----AERNAACGRI 689

Query: 748  LCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMELIEYGETDA 807
            +CD  + +++L++  SY L+ L    L   R  + P  +   +  +  L+ ++E    DA
Sbjct: 690  ICDIEISAKELIRCKSYHLSELVHQILKAERVVIPPENIRNAYNDSVHLLYMLENTWIDA 749

Query: 808  WLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIVPDKFSN 867
               +++M  L+VLPL  Q+TN++GN+  +TL G R++R EYLLLH F +  +IVPDK   
Sbjct: 750  KFILQIMCELNVLPLALQITNIAGNVMSRTLMGGRSERNEYLLLHAFTENNFIVPDK--- 806

Query: 868  YAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNK--KAASYAGGLVLEPK 925
                  + K+     V+D              ND   +D  KNK  K A+YAGGLVLEPK
Sbjct: 807  -----PVFKKMQQTTVED--------------NDDMGTDQNKNKSRKKAAYAGGLVLEPK 847

Query: 926  KGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSS--------DDSFPRLPSSKTT-GVL 976
             G YDK+ILLLDFNSLYPSIIQEYNICFTTV R +         D  P LP S    G+L
Sbjct: 848  VGFYDKFILLLDFNSLYPSIIQEYNICFTTVHREAPSTQKGEDQDEIPELPHSDLEMGIL 907

Query: 977  PELLKKLVKLRREKKTWMKTASGLKRQ---QLDIEQQALKLTANSMYGCLGFSNSRFYAK 1033
            P  ++KLV+ RR  K  MK    L      Q DI Q+ALKLTANSMYGCLGFS SRFYAK
Sbjct: 908  PREIRKLVERRRHVKQLMKQPD-LNPDLYLQYDIRQKALKLTANSMYGCLGFSYSRFYAK 966

Query: 1034 PLAELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEV 1093
            PLA L+T QGREIL  T ++VQ  +NLEVIYGDTDSIMI +  +++ +   +  +V  E+
Sbjct: 967  PLAALVTHQGREILLHTKEMVQK-MNLEVIYGDTDSIMINTNCNNLEEVFKLGNRVKSEI 1025

Query: 1094 NKKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQ-FKDGTPYEVIERKGLDIVRRDWSLLAK 1152
            NK Y+ LEID+DG++K +LLLKKKKYAA+ V+   DG      E KGLDIVRRDW  LAK
Sbjct: 1026 NKSYKLLEIDIDGIFKSLLLLKKKKYAALTVEPTGDGKYVTKQELKGLDIVRRDWCELAK 1085

Query: 1153 DLGDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDA 1212
              G++ ++QILS    + +VE+I   L ++ E + NG V + +Y I K LTK P+ YPD 
Sbjct: 1086 QAGNYVISQILSDQPRDSIVENIQKKLTEIGENVTNGTVPITQYEINKALTKDPQDYPDK 1145

Query: 1213 KNQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRARHPDELKQEQG 1272
            K+ PHV VA  +  QG       GDTI YVIC  Q GS+ SA+    +  +  E  Q+Q 
Sbjct: 1146 KSLPHVHVALWINSQGGRK-VKAGDTISYVIC--QDGSNLSAS----QRAYAQEQLQKQE 1198

Query: 1273 TWLIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQHKSSEASDDPTSSLL 1332
               ID  YYLSQQ+HPV++R+C  I G     +A  LGLD S+F+       D+   +LL
Sbjct: 1199 NLSIDTQYYLSQQVHPVVARICEPIDGIDSALIAMWLGLDPSQFRAHRHYQQDEENDALL 1258

Query: 1333 FAGDDEESEKPTSSGTDESDYNFWR--KLCCPKC----------------FENGAGRIS- 1373
                        S  TDE  Y      K  CPKC                 E G  R S 
Sbjct: 1259 GG---------PSQLTDEEKYRDCERFKFFCPKCGTENIYDNVFDGSGLQIEPGLKRCSK 1309

Query: 1374 ----------AAMIANQVKRQAEKFVLMYYRGLLMCDDETCKHTTRSVSFRLVGDSERGT 1423
                         + N++     +++  YY G L+C+++TC++ TR +       S  G 
Sbjct: 1310 PECDASPLDYVIQVHNKLLLDIRRYIKKYYSGWLVCEEKTCQNRTRRLPLSF---SRNGP 1366

Query: 1424 VCPNYPRCNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEK-MEAKSRIPIEKELI-KIRP 1481
            +C    +    L  +Y E  LY QL ++  +FD    +EK +  + R  ++K+L  +   
Sbjct: 1367 ICQACSKAT--LRSEYPEKALYTQLCFYRFIFDWDYALEKVVSEQERGHLKKKLFQESEN 1424

Query: 1482 IVDLAASTIQKIRDRCAFGWVKLQDL 1507
                  ST+ ++  R  +  V L  L
Sbjct: 1425 QYKKLKSTVDQVLSRSGYSEVNLSKL 1450


>UniRef100_UPI00003A9D8C UPI00003A9D8C UniRef100 entry
          Length = 1431

 Score =  691 bits (1782), Expect = 0.0
 Identities = 449/1165 (38%), Positives = 643/1165 (54%), Gaps = 137/1165 (11%)

Query: 382  VW--QGTLYQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQD 439
            VW      Y SCCV VKN++R VY +P        EM        E+ ++  +  K+  D
Sbjct: 340  VWIESANTYVSCCVTVKNIERTVYLLPRE-----TEMDLSSGKETETPVTIMNVFKEFND 394

Query: 440  AVSDTKNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDL 499
             +S  K +I K         F    V++ YAFE  D+PA   Y+ ++ Y  +   LP DL
Sbjct: 395  CISP-KYKIMK---------FKSKKVEKYYAFEIPDVPAKSEYL-EVKYSAEYPRLPQDL 443

Query: 500  KGKSFCALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDI 559
            KG++F    G   S+LEL L+ RKIKGP WL++ N     ++Q VSWCK E +   P  +
Sbjct: 444  KGETFSHAFGTNTSSLELLLMSRKIKGPCWLEIKNPQP--SNQSVSWCKVEAVAMKPGLV 501

Query: 560  RASSPSSSKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWK 619
                          PP+VV + ++KT  N K + NEIV+ + +      +D         
Sbjct: 502  NVVKDLPPP-----PPLVVMSFSMKTIQNPKTHQNEIVAMAALIHQKFPLDKAP-----P 551

Query: 620  RPGMLTHFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMD 679
            +P   THF  + K +  IFP  F  E+  +N K     + + ++ER LL   + ++HK+D
Sbjct: 552  QPPFQTHFCAVSKPNDCIFPYDFKEEIKKKNAK-----IEIAATERTLLGFFLAKIHKID 606

Query: 680  SDVLVGHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAI 739
             DV+VGHNI GFDL+VLL R   C+VP   WSK+GRL RS MPKL  RG   GFG   A 
Sbjct: 607  PDVVVGHNIYGFDLEVLLQRINVCKVPH--WSKIGRLRRSNMPKLGGRG---GFGERNA- 660

Query: 740  MSCVAGRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMEL 799
                 GR++CD  + +++L++  SY L+ L    L   R  + P E+  ++  +  L+ +
Sbjct: 661  ---ACGRMICDVEISAKELIRCKSYHLSELVHQILKTERVTILPEEIRNLYSDSPHLLFM 717

Query: 800  IEYGETDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKY 859
            +E   TDA   +++M  L+VLPL  Q+TN+SGN+  +T+ G R++R E+LLLH F++K Y
Sbjct: 718  LENTWTDAKFILQIMCELNVLPLALQITNISGNVMSRTMMGGRSERNEFLLLHAFYEKDY 777

Query: 860  IVPDKFSNYAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNKKAASYAGG 919
            IVPDK        ++ K+ +   VD    +D D  D N          K  KK A+YAGG
Sbjct: 778  IVPDK--------QVFKKPLQKLVD----EDEDFEDQN--------KSKIGKKKAAYAGG 817

Query: 920  LVLEPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSS-----------DDSFPRLP 968
            LVL+PK G YDK+ILLLDFNSLYPSIIQE+NICFTTV+R S           ++  P LP
Sbjct: 818  LVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVQRLSSEAQKRAEVEEEEEIPELP 877

Query: 969  S-SKTTGVLPELLKKLVKLRREKKTWMK--TASGLKRQQLDIEQQALKLTANSMYGCLGF 1025
              S   G+LP+ ++KLV+ RR+ K  MK    +     Q DI Q+ALKLTANSMYGCLGF
Sbjct: 878  DPSLEMGILPKEIRKLVERRRQVKQLMKQPDLNPDLYLQYDIRQKALKLTANSMYGCLGF 937

Query: 1026 SNSRFYAKPLAELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSI 1085
            S SRFYAKPLA L+T +GREIL  T ++VQ  +NLEVIYGDTDSIMI +   ++ +   +
Sbjct: 938  SYSRFYAKPLAALVTHKGREILMHTKEMVQ-KMNLEVIYGDTDSIMINTNSTNLDEVFKL 996

Query: 1086 SKKVIQEVNKKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQ-FKDGTPYEVIERKGLDIVR 1144
              K+  EVNK Y+ LEID+DG++K +LLLKKKKYAA+ V+   DG      E KGLDIVR
Sbjct: 997  GNKIKSEVNKLYKLLEIDIDGVFKSLLLLKKKKYAALTVEPTGDGKYVTKQELKGLDIVR 1056

Query: 1145 RDWSLLAKDLGDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTK 1204
            RDW  LAK+ G++ + QILS    + +VE+I   L+++ E + NGQ+ + ++ I K LTK
Sbjct: 1057 RDWCDLAKETGNYVIGQILSDQPRDIIVENIQRRLIEIGENVINGQIPVNQFEINKALTK 1116

Query: 1205 PPEAYPDAKNQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRARHP 1264
             P+ YPD K+ PHV VA  +  QG       GDT+ Y+IC  Q GS+ SA   + RA  P
Sbjct: 1117 DPQDYPDKKSLPHVHVAMWINSQGGRK-VKAGDTVSYIIC--QDGSNLSA---SQRAYAP 1170

Query: 1265 DELKQEQGTWLIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQHKSSEAS 1324
            ++L Q+Q    ID  YYLSQQIHPV++R+C  I+G     +A  LGLD S+F+       
Sbjct: 1171 EQL-QKQDNLTIDTQYYLSQQIHPVVARICEPIEGIDSVLIATWLGLDPSQFRVHHHYHK 1229

Query: 1325 DDPTSSLLFAGDDEESEKPTSSGTDESDYNFWR--KLCCPKC-----FEN---GAGRISA 1374
            D+   +L+            +  TDE  Y      K CC KC     ++N    +GR   
Sbjct: 1230 DEENDALVGG---------PAQLTDEEKYRDCERFKFCCLKCGTENIYDNVFDCSGRFIE 1280

Query: 1375 AMIANQVKRQAE-------------------KFVLMYYRGLLMCDDETCKHTTRSVSFRL 1415
              +    K + E                   +++  YY G L+C+D TC++ TR +    
Sbjct: 1281 PSLQRCSKSECEEPPFNHVVQMNNKLLLDIRRYLKKYYNGWLICEDPTCQNRTRRLPLSF 1340

Query: 1416 VGDSERGTVCPNYPRCNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKMEAKSRIPIEKE 1475
               S  G +C    +    L  +Y++  LY QL ++ ++FD     +K+  +     ++E
Sbjct: 1341 ---SRSGPICQACRK--AILRPEYSDKALYTQLCFYRYIFDVEYATDKVITEE----DRE 1391

Query: 1476 LIKIRPIVDLAASTIQKIR---DRC 1497
             ++ +P+    +   +K++   D+C
Sbjct: 1392 FVRRKPLRKEVSEAYRKLKSTVDKC 1416


>UniRef100_UPI00003A9D8B UPI00003A9D8B UniRef100 entry
          Length = 1440

 Score =  691 bits (1782), Expect = 0.0
 Identities = 449/1165 (38%), Positives = 643/1165 (54%), Gaps = 137/1165 (11%)

Query: 382  VW--QGTLYQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQD 439
            VW      Y SCCV VKN++R VY +P        EM        E+ ++  +  K+  D
Sbjct: 342  VWIESANTYVSCCVTVKNIERTVYLLPRE-----TEMDLSSGKETETPVTIMNVFKEFND 396

Query: 440  AVSDTKNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDL 499
             +S  K +I K         F    V++ YAFE  D+PA   Y+ ++ Y  +   LP DL
Sbjct: 397  CISP-KYKIMK---------FKSKKVEKYYAFEIPDVPAKSEYL-EVKYSAEYPRLPQDL 445

Query: 500  KGKSFCALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDI 559
            KG++F    G   S+LEL L+ RKIKGP WL++ N     ++Q VSWCK E +   P  +
Sbjct: 446  KGETFSHAFGTNTSSLELLLMSRKIKGPCWLEIKNPQP--SNQSVSWCKVEAVAMKPGLV 503

Query: 560  RASSPSSSKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWK 619
                          PP+VV + ++KT  N K + NEIV+ + +      +D         
Sbjct: 504  NVVKDLPPP-----PPLVVMSFSMKTIQNPKTHQNEIVAMAALIHQKFPLDKAP-----P 553

Query: 620  RPGMLTHFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMD 679
            +P   THF  + K +  IFP  F  E+  +N K     + + ++ER LL   + ++HK+D
Sbjct: 554  QPPFQTHFCAVSKPNDCIFPYDFKEEIKKKNAK-----IEIAATERTLLGFFLAKIHKID 608

Query: 680  SDVLVGHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAI 739
             DV+VGHNI GFDL+VLL R   C+VP   WSK+GRL RS MPKL  RG   GFG   A 
Sbjct: 609  PDVVVGHNIYGFDLEVLLQRINVCKVPH--WSKIGRLRRSNMPKLGGRG---GFGERNA- 662

Query: 740  MSCVAGRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMEL 799
                 GR++CD  + +++L++  SY L+ L    L   R  + P E+  ++  +  L+ +
Sbjct: 663  ---ACGRMICDVEISAKELIRCKSYHLSELVHQILKTERVTILPEEIRNLYSDSPHLLFM 719

Query: 800  IEYGETDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKY 859
            +E   TDA   +++M  L+VLPL  Q+TN+SGN+  +T+ G R++R E+LLLH F++K Y
Sbjct: 720  LENTWTDAKFILQIMCELNVLPLALQITNISGNVMSRTMMGGRSERNEFLLLHAFYEKDY 779

Query: 860  IVPDKFSNYAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNKKAASYAGG 919
            IVPDK        ++ K+ +   VD    +D D  D N          K  KK A+YAGG
Sbjct: 780  IVPDK--------QVFKKPLQKLVD----EDEDFEDQN--------KSKIGKKKAAYAGG 819

Query: 920  LVLEPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSS-----------DDSFPRLP 968
            LVL+PK G YDK+ILLLDFNSLYPSIIQE+NICFTTV+R S           ++  P LP
Sbjct: 820  LVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVQRLSSEAQKRAEVEEEEEIPELP 879

Query: 969  S-SKTTGVLPELLKKLVKLRREKKTWMK--TASGLKRQQLDIEQQALKLTANSMYGCLGF 1025
              S   G+LP+ ++KLV+ RR+ K  MK    +     Q DI Q+ALKLTANSMYGCLGF
Sbjct: 880  DPSLEMGILPKEIRKLVERRRQVKQLMKQPDLNPDLYLQYDIRQKALKLTANSMYGCLGF 939

Query: 1026 SNSRFYAKPLAELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSI 1085
            S SRFYAKPLA L+T +GREIL  T ++VQ  +NLEVIYGDTDSIMI +   ++ +   +
Sbjct: 940  SYSRFYAKPLAALVTHKGREILMHTKEMVQ-KMNLEVIYGDTDSIMINTNSTNLDEVFKL 998

Query: 1086 SKKVIQEVNKKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQ-FKDGTPYEVIERKGLDIVR 1144
              K+  EVNK Y+ LEID+DG++K +LLLKKKKYAA+ V+   DG      E KGLDIVR
Sbjct: 999  GNKIKSEVNKLYKLLEIDIDGVFKSLLLLKKKKYAALTVEPTGDGKYVTKQELKGLDIVR 1058

Query: 1145 RDWSLLAKDLGDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTK 1204
            RDW  LAK+ G++ + QILS    + +VE+I   L+++ E + NGQ+ + ++ I K LTK
Sbjct: 1059 RDWCDLAKETGNYVIGQILSDQPRDIIVENIQRRLIEIGENVINGQIPVNQFEINKALTK 1118

Query: 1205 PPEAYPDAKNQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRARHP 1264
             P+ YPD K+ PHV VA  +  QG       GDT+ Y+IC  Q GS+ SA   + RA  P
Sbjct: 1119 DPQDYPDKKSLPHVHVAMWINSQGGRK-VKAGDTVSYIIC--QDGSNLSA---SQRAYAP 1172

Query: 1265 DELKQEQGTWLIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQHKSSEAS 1324
            ++L Q+Q    ID  YYLSQQIHPV++R+C  I+G     +A  LGLD S+F+       
Sbjct: 1173 EQL-QKQDNLTIDTQYYLSQQIHPVVARICEPIEGIDSVLIATWLGLDPSQFRVHHHYHK 1231

Query: 1325 DDPTSSLLFAGDDEESEKPTSSGTDESDYNFWR--KLCCPKC-----FEN---GAGRISA 1374
            D+   +L+            +  TDE  Y      K CC KC     ++N    +GR   
Sbjct: 1232 DEENDALVGG---------PAQLTDEEKYRDCERFKFCCLKCGTENIYDNVFDCSGRFIE 1282

Query: 1375 AMIANQVKRQAE-------------------KFVLMYYRGLLMCDDETCKHTTRSVSFRL 1415
              +    K + E                   +++  YY G L+C+D TC++ TR +    
Sbjct: 1283 PSLQRCSKSECEEPPFNHVVQMNNKLLLDIRRYLKKYYNGWLICEDPTCQNRTRRLPLSF 1342

Query: 1416 VGDSERGTVCPNYPRCNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKMEAKSRIPIEKE 1475
               S  G +C    +    L  +Y++  LY QL ++ ++FD     +K+  +     ++E
Sbjct: 1343 ---SRSGPICQACRK--AILRPEYSDKALYTQLCFYRYIFDVEYATDKVITEE----DRE 1393

Query: 1476 LIKIRPIVDLAASTIQKIR---DRC 1497
             ++ +P+    +   +K++   D+C
Sbjct: 1394 FVRRKPLRKEVSEAYRKLKSTVDKC 1418


>UniRef100_UPI00003A9D8E UPI00003A9D8E UniRef100 entry
          Length = 1394

 Score =  686 bits (1771), Expect = 0.0
 Identities = 444/1129 (39%), Positives = 626/1129 (55%), Gaps = 130/1129 (11%)

Query: 382  VW--QGTLYQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQD 439
            VW      Y SCCV VKN++R VY +P        EM        E+ ++  +  K+  D
Sbjct: 350  VWIESANTYVSCCVTVKNIERTVYLLPRE-----TEMDLSSGKETETPVTIMNVFKEFND 404

Query: 440  AVSDTKNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDL 499
             +S  K +I K         F    V++ YAFE  D+PA   Y+ ++ Y  +   LP DL
Sbjct: 405  CISP-KYKIMK---------FKSKKVEKYYAFEIPDVPAKSEYL-EVKYSAEYPRLPQDL 453

Query: 500  KGKSFCALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDI 559
            KG++F    G   S+LEL L+ RKIKGP WL++ N     ++Q VSWCK E +   P  +
Sbjct: 454  KGETFSHAFGTNTSSLELLLMSRKIKGPCWLEIKNPQP--SNQSVSWCKVEAVAMKPGLV 511

Query: 560  RASSPSSSKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWK 619
                          PP+VV + ++KT  N K + NEIV+ + +      +D         
Sbjct: 512  NVVKDLPPP-----PPLVVMSFSMKTIQNPKTHQNEIVAMAALIHQKFPLDKAP-----P 561

Query: 620  RPGMLTHFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMD 679
            +P   THF  + K +  IFP  F  E+  +N K     + + ++ER LL   + ++HK+D
Sbjct: 562  QPPFQTHFCAVSKPNDCIFPYDFKEEIKKKNAK-----IEIAATERTLLGFFLAKIHKID 616

Query: 680  SDVLVGHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAI 739
             DV+VGHNI GFDL+VLL R   C+VP   WSK+GRL RS MPKL  RG   GFG   A 
Sbjct: 617  PDVVVGHNIYGFDLEVLLQRINVCKVPH--WSKIGRLRRSNMPKLGGRG---GFGERNA- 670

Query: 740  MSCVAGRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMEL 799
                 GR++CD  + +++L++  SY L+ L    L   R  + P E+  ++  +  L+ +
Sbjct: 671  ---ACGRMICDVEISAKELIRCKSYHLSELVHQILKTERVTILPEEIRNLYSDSPHLLFM 727

Query: 800  IEYGETDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKY 859
            +E   TDA   +++M  L+VLPL  Q+TN+SGN+  +T+ G R++R E+LLLH F++K Y
Sbjct: 728  LENTWTDAKFILQIMCELNVLPLALQITNISGNVMSRTMMGGRSERNEFLLLHAFYEKDY 787

Query: 860  IVPDKFSNYAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNKKAASYAGG 919
            IVPDK        ++ K+ +   VD    +D D  D N          K  KK A+YAGG
Sbjct: 788  IVPDK--------QVFKKPLQKLVD----EDEDFEDQN--------KSKIGKKKAAYAGG 827

Query: 920  LVLEPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSS-----------DDSFPRLP 968
            LVL+PK G YDK+ILLLDFNSLYPSIIQE+NICFTTV+R S           ++  P LP
Sbjct: 828  LVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVQRLSSEAQKRAEVEEEEEIPELP 887

Query: 969  S-SKTTGVLPELLKKLVKLRREKKTWMK--TASGLKRQQLDIEQQALKLTANSMYGCLGF 1025
              S   G+LP+ ++KLV+ RR+ K  MK    +     Q DI Q+ALKLTANSMYGCLGF
Sbjct: 888  DPSLEMGILPKEIRKLVERRRQVKQLMKQPDLNPDLYLQYDIRQKALKLTANSMYGCLGF 947

Query: 1026 SNSRFYAKPLAELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSI 1085
            S SRFYAKPLA L+T +GREIL  T ++VQ  +NLEVIYGDTDSIMI +   ++ +   +
Sbjct: 948  SYSRFYAKPLAALVTHKGREILMHTKEMVQ-KMNLEVIYGDTDSIMINTNSTNLDEVFKL 1006

Query: 1086 SKKVIQEVNKKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQ-FKDGTPYEVIERKGLDIVR 1144
              K+  EVNK Y+ LEID+DG++K +LLLKKKKYAA+ V+   DG      E KGLDIVR
Sbjct: 1007 GNKIKSEVNKLYKLLEIDIDGVFKSLLLLKKKKYAALTVEPTGDGKYVTKQELKGLDIVR 1066

Query: 1145 RDWSLLAKDLGDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTK 1204
            RDW  LAK+ G++ + QILS    + +VE+I   L+++ E + NGQ+ + ++ I K LTK
Sbjct: 1067 RDWCDLAKETGNYVIGQILSDQPRDIIVENIQRRLIEIGENVINGQIPVNQFEINKALTK 1126

Query: 1205 PPEAYPDAKNQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRARHP 1264
             P+ YPD K+ PHV VA  +  QG       GDT+ Y+IC  Q GS+ SA   + RA  P
Sbjct: 1127 DPQDYPDKKSLPHVHVAMWINSQGGRK-VKAGDTVSYIIC--QDGSNLSA---SQRAYAP 1180

Query: 1265 DELKQEQGTWLIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQHKSSEAS 1324
            ++L Q+Q    ID  YYLSQQIHPV++R+C  I+G     +A  LGLD S+F+       
Sbjct: 1181 EQL-QKQDNLTIDTQYYLSQQIHPVVARICEPIEGIDSVLIATWLGLDPSQFRVHHHYHK 1239

Query: 1325 DDPTSSLLFAGDDEESEKPTSSGTDESDYNFWR--KLCCPKC-----FEN---GAGRISA 1374
            D+   +L+            +  TDE  Y      K CC KC     ++N    +GR   
Sbjct: 1240 DEENDALVGG---------PAQLTDEEKYRDCERFKFCCLKCGTENIYDNVFDCSGRFIE 1290

Query: 1375 AMIANQVKRQAE-------------------KFVLMYYRGLLMCDDETCKHTTRSVSFRL 1415
              +    K + E                   +++  YY G L+C+D TC++ TR +    
Sbjct: 1291 PSLQRCSKSECEEPPFNHVVQMNNKLLLDIRRYLKKYYNGWLICEDPTCQNRTRRLPLSF 1350

Query: 1416 VGDSERGTVCPNYPRCNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKM 1464
               S  G +C    +    L  +Y++  LY QL ++ ++FD     +K+
Sbjct: 1351 ---SRSGPICQACRK--AILRPEYSDKALYTQLCFYRYIFDVEYATDKV 1394


>UniRef100_UPI00003C2140 UPI00003C2140 UniRef100 entry
          Length = 1667

 Score =  686 bits (1769), Expect = 0.0
 Identities = 450/1183 (38%), Positives = 620/1183 (52%), Gaps = 174/1183 (14%)

Query: 388  YQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQDAVSDTKNE 447
            Y SCC+ V  ++RC++ +P           QLE   +  R  P       +D + D   E
Sbjct: 501  YVSCCLTVNGIERCIFLLPRSK--------QLENGHETDR--PVG-----EDEIYDEFEE 545

Query: 448  I-AKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSFCA 506
            + AKH    G+  F    V RKYAFE+  +PA  NY+ KI Y F +  LP D KGK+F  
Sbjct: 546  LSAKH----GIKGFLSKWVTRKYAFEQAGVPAESNYM-KIRYGFDEPQLPFDFKGKTFSK 600

Query: 507  LLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSPSS 566
              G   S  EL ++KR+I GPSWL++SN S    S  +SWCK EV +D PKDI   S + 
Sbjct: 601  AFGTNTSPFELLVVKRRIFGPSWLKISNASLAEGSTPISWCKMEVSIDDPKDISPISDAD 660

Query: 567  SKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGMLTH 626
            +      PP+ V +I ++T +N K+N  E+V+ S  +    +I+ P    +       + 
Sbjct: 661  TTSPRETPPLTVMSIAIRTVVNHKENKQELVAVSARTWTDHQIEDPTPPEQLP----CSV 716

Query: 627  FTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSDVLVGH 686
            FT +R L G +FP GF  E     IK     +     ER LLN L+ Q++  D DV+VGH
Sbjct: 717  FTAVRPL-GTMFPPGFEAEARKGRIK-----IHTLKYERMLLNALLAQIYNADPDVIVGH 770

Query: 687  NISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMSCVAGR 746
              +G  LDVLLHR +  R  +  WS++GR  R   PKL ++G           +  +AGR
Sbjct: 771  EFNGVSLDVLLHRMRDLR--ADHWSRVGRFRRPKWPKL-KQGLN---------LKILAGR 818

Query: 747  LLCDTYLCS---RDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQ----TAKSLMEL 799
            L+CD  L S   + ++   ++SLT +  T L   R+++ P E    F     + + LM  
Sbjct: 819  LVCD--LASDNGKSMITSTTWSLTEMCGTHLKIQREDIDPEETASFFDSLAPSPERLMNF 876

Query: 800  IEYGETDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKY 859
            + + E D +  M +   + +LPLT+QLTNL+GN W KTL G RA+R EY+LLH+FH++KY
Sbjct: 877  VRHCEVDTFFQMAIAAKVQILPLTKQLTNLAGNSWNKTLNGGRAERNEYILLHDFHRQKY 936

Query: 860  IVPDKFSNYAK-------ETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNKK 912
            I PDK S + K       E K   R  ++G                  D+S S    N K
Sbjct: 937  ICPDKISAWEKKQIQQAAELKAKARAKSNG---------------GAADSSASTTAANSK 981

Query: 913  AASYAGGLVLEPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVER-------------- 958
               + GGLV EPK+GL+DKYIL++DFNSLYPSIIQE+NI FTTVER              
Sbjct: 982  KDKFKGGLVFEPKRGLWDKYILVMDFNSLYPSIIQEFNIDFTTVERPPTQGIEDDEIGVA 1041

Query: 959  ----SSD-------------DSFPRLPSSKT-TGVLPELLKKLVKLRREKKTWMKTASGL 1000
                SSD             D  P +PSS    GVLP ++ +LV  RR+ K+ MK  S  
Sbjct: 1042 AATASSDTAGEAGADAAADVDKIPDVPSSDVEQGVLPRIIAQLVARRRQVKSLMKDKSAT 1101

Query: 1001 KRQ--QLDIEQQALKLTANSMYGCLGFSNSRFYAKPLAELITLQGREILQSTVDLVQNNL 1058
              Q  Q +I+Q ALKLTANSMYGCLGF NSRFYA+PLA L T +GREIL +T DL ++ L
Sbjct: 1102 PSQLLQWNIKQLALKLTANSMYGCLGFENSRFYARPLAALTTFKGREILTATKDLAESML 1161

Query: 1059 NLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEVNKKYRCLEIDLDGLYKRMLLLKKKK 1118
             L+VIYGDTDS+MI +   +  +A  I ++  + VN++YR LEID+DG+++RMLLL+KKK
Sbjct: 1162 -LDVIYGDTDSVMINTNATEYREALRIGQEFKKSVNERYRLLEIDIDGVFERMLLLQKKK 1220

Query: 1119 YAAVKVQFKDGTPYEVIERKGLDIVRRDWSLLAKDLGDFCLTQILSGGSCEDVVESIHNS 1178
            YAAV V  +     E+   KGLD+ RR++S L+K++ ++ L QILSG + E VVE IH  
Sbjct: 1221 YAAVLVDEEGKRSTEI---KGLDMKRREYSALSKNVSNYVLEQILSGQATELVVEHIHEY 1277

Query: 1179 LMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDAKNQPHVLVAQRLKQQGYTSGCSVGDT 1238
            L  +  +++ G+V L+ ++I K L K PE YPD K+QPHV VA R+K +G      +GD 
Sbjct: 1278 LSDISTKIKMGEVGLDDFIIYKRLGKNPEDYPDVKSQPHVQVALRMKTRG--GNARMGDV 1335

Query: 1239 IPYVICCEQGGSSGSATGIALRARHPDELKQEQGTWLIDIDYYLSQQIHPVISRLCASIQ 1298
            IPY+ C  + G+S + T  A RA HPDEL+++     ID ++YL+ QI P + RLC SI+
Sbjct: 1336 IPYIFCLGEDGTSSTKTAQAERAHHPDELRRKDSELKIDYEHYLALQILPPVERLCESIE 1395

Query: 1299 GTSPERLADCLGLDTSKFQHKS-SEASDDPTSSLLFAGDDEESEKPTSSGTDESDYNFWR 1357
            GT   RLA+CLGLD SK+ H S S A         FA  D +          E       
Sbjct: 1396 GTDRSRLAECLGLDPSKYSHVSHSGAGSGGAVGREFATLDSQIPDEVRFAQCEP-----L 1450

Query: 1358 KLCCPKCFENGA-------------------------------------------GRISA 1374
            KL CP C E+                                               +  
Sbjct: 1451 KLTCPSCRESSTFLGPAHRAASSAIKVLGDSTNTQRSEPNAISTKGIRCTNAACQRMLPL 1510

Query: 1375 AMIANQVKRQAEKFVLMYYRGLLMCDDETCKHTTRSVSFR-----LVGDSERGTVCP--- 1426
            A +A Q++     FV  YY G   C D  C   TR  S        V D++   +     
Sbjct: 1511 ATMAIQLELAIRSFVERYYAGWTECSDPNCGSRTRLASVYAKRCVAVHDAKSAALLDATS 1570

Query: 1427 ---NYPRCNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKMEA 1466
               ++  C G +   Y +  LY QL Y   +FD+    EK+ A
Sbjct: 1571 TTGSHLACRGRVEPVYRDKQLYDQLIYLESLFDSSRIREKVTA 1613


>UniRef100_Q86UQ7 Polymerase (DNA directed), alpha [Homo sapiens]
          Length = 1462

 Score =  685 bits (1768), Expect = 0.0
 Identities = 445/1170 (38%), Positives = 640/1170 (54%), Gaps = 142/1170 (12%)

Query: 390  SCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQDAVSDTKNEIA 449
            SCCV+VKN++R +Y +P       N   +       + IS  D  ++  + ++ TK +I 
Sbjct: 375  SCCVMVKNIERTLYFLPREMKIDLNTGKETG-----TPISMKDVYEEFDEKIA-TKYKIM 428

Query: 450  KHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSFCALLG 509
            K         F   PV++ YAFE  D+P    Y+ ++ Y  +   LP DLKG++F  + G
Sbjct: 429  K---------FKSKPVEKNYAFEIPDVPEKSEYL-EVKYSAEMPQLPQDLKGETFSHVFG 478

Query: 510  ARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSPSSSKI 569
               S+LELFL+ RKIKGP WL+V   S    +Q VSWCK E +   P  +      S   
Sbjct: 479  TNTSSLELFLMNRKIKGPCWLEVK--SPQLLNQPVSWCKVEAMALKPDLVNVIKDVSP-- 534

Query: 570  TLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGMLTHFTV 629
                PP+VV A ++KT  N K + NEI++ + +  +   +D         +P   +HF V
Sbjct: 535  ----PPLVVMAFSMKTMQNAKNHQNEIIAMAALVHHSFALDKAA-----PKPPFQSHFCV 585

Query: 630  IRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSDVLVGHNIS 689
            + K    IFP  F   +  +N+K       V ++ER LL   + ++HK+D D++VGHNI 
Sbjct: 586  VSKPKDCIFPYAFKEVIEKKNVKVE-----VAATERTLLGFFLAKVHKIDPDIIVGHNIY 640

Query: 690  GFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMSCVAGRLLC 749
            GF+L+VLL R   C+ P   WSK+GRL RS MPKL  R    GFG   A      GR++C
Sbjct: 641  GFELEVLLQRINVCKAPH--WSKIGRLKRSNMPKLGGRS---GFGERNA----TCGRMIC 691

Query: 750  DTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMELIEYGETDAWL 809
            D  + +++L++  SY L+ L +  L   R  +    +  M+  +  L+ L+E+   DA  
Sbjct: 692  DVEISAKELIRCKSYHLSELVQQILKTERVVIPMENIQNMYSESSQLLYLLEHTWKDAKF 751

Query: 810  SMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIVPDKFSNYA 869
             +++M  L+VLPL  Q+TN++GN+  +TL G R++R E+LLLH F++  YIVPDK     
Sbjct: 752  ILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFLLLHAFYENNYIVPDKQIFRK 811

Query: 870  KETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNKKAASYAGGLVLEPKKGLY 929
             + KL                    D +   D   + +KK +K A+YAGGLVL+PK G Y
Sbjct: 812  PQQKL-------------------GDEDEEIDGDTNKYKKGRKKAAYAGGLVLDPKVGFY 852

Query: 930  DKYILLLDFNSLYPSIIQEYNICFTTVERSSDDS-----------FPRLPS-SKTTGVLP 977
            DK+ILLLDFNSLYPSIIQE+NICFTTV+R + ++            P LP  S   G+LP
Sbjct: 853  DKFILLLDFNSLYPSIIQEFNICFTTVQRVASEAQKVTEDGEQEQIPELPDPSLEMGILP 912

Query: 978  ELLKKLVKLRREKKTWMKTASGLKRQ---QLDIEQQALKLTANSMYGCLGFSNSRFYAKP 1034
              ++KLV+ R++ K  MK    L      Q DI Q+ALKLTANSMYGCLGFS SRFYAKP
Sbjct: 913  REIRKLVERRKQVKQLMKQQD-LNPDLILQYDIRQKALKLTANSMYGCLGFSYSRFYAKP 971

Query: 1035 LAELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEVN 1094
            LA L+T +GREIL  T ++VQ  +NLEVIYGDTDSIMI +   ++ +   +  KV  EVN
Sbjct: 972  LAALVTYKGREILMHTKEMVQK-MNLEVIYGDTDSIMINTNSTNLEEVFKLGNKVKSEVN 1030

Query: 1095 KKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQ-FKDGTPYEVIERKGLDIVRRDWSLLAKD 1153
            K Y+ LEID+DG++K +LLLKKKKYAA+ V+   DG      E KGLDIVRRDW  LAKD
Sbjct: 1031 KLYKLLEIDIDGVFKSLLLLKKKKYAALVVEPTSDGNYVTKQELKGLDIVRRDWCDLAKD 1090

Query: 1154 LGDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDAK 1213
             G+F + QILS  S + +VE+I   L+++ E + NG V + ++ I K LTK P+ YPD K
Sbjct: 1091 TGNFVIGQILSDQSRDTIVENIQKRLIEIGENVLNGSVPVSQFEINKALTKDPQDYPDKK 1150

Query: 1214 NQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRARHPDELKQEQGT 1273
            + PHV VA  +  QG       GDT+ YVIC  Q GS+ +A+    RA  P++L Q+Q  
Sbjct: 1151 SLPHVHVALWINSQGGRK-VKAGDTVSYVIC--QDGSNLTASQ---RAYAPEQL-QKQDN 1203

Query: 1274 WLIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQ----HKSSEASDDPTS 1329
              ID  YYL+QQIHPV++R+C  I G     +A  LGLD ++F+    HK  E      +
Sbjct: 1204 LTIDTQYYLAQQIHPVVARICEPIDGIDAVLIATWLGLDPTQFRVHHYHKDEE------N 1257

Query: 1330 SLLFAGDDEESEKPTSSGTDESDYNFWRKLCCP-------KCFEN---GAG--------R 1371
              L  G  +         TDE  Y    +  CP         ++N   G+G        R
Sbjct: 1258 DALLGGPAQL--------TDEEKYRDCERFKCPCPTCGTENIYDNVFDGSGTDMEPSLYR 1309

Query: 1372 IS-----------AAMIANQVKRQAEKFVLMYYRGLLMCDDETCKHTTRSVSFRLVGDSE 1420
             S              ++N++     +F+  YY G L+C++ TC++ TR +  +    S 
Sbjct: 1310 CSNIDCKASPLTFTVQLSNKLIMDIRRFIKKYYDGWLICEEPTCRNRTRHLPLQF---SR 1366

Query: 1421 RGTVCPNYPRCNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKMEA-KSRIPIEKELIKI 1479
             G +CP   +    L  +Y++  LY QL ++ ++FD  C +EK+     +  ++K+    
Sbjct: 1367 TGPLCPACMKAT--LQPEYSDKSLYTQLCFYRYIFDAECALEKLTTDHEKDKLKKQFFTP 1424

Query: 1480 RPIVDL--AASTIQKIRDRCAFGWVKLQDL 1507
            + + D     +T ++   R  +  V L  L
Sbjct: 1425 KVLQDYRKLKNTAEQFLSRSGYSEVNLSKL 1454


>UniRef100_P09884 DNA polymerase alpha catalytic subunit [Homo sapiens]
          Length = 1462

 Score =  685 bits (1767), Expect = 0.0
 Identities = 443/1170 (37%), Positives = 640/1170 (53%), Gaps = 142/1170 (12%)

Query: 390  SCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQDAVSDTKNEIA 449
            SCCV+VKN++R +Y +P       N   +       + IS  D  ++  + ++ TK +I 
Sbjct: 375  SCCVMVKNIERTLYFLPREMKIDLNTGKETG-----TPISMKDVYEEFDEKIA-TKYKIM 428

Query: 450  KHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSFCALLG 509
            K         F   PV++ YAFE  D+P    Y+ ++ Y  +   LP DLKG++F  + G
Sbjct: 429  K---------FKSKPVEKNYAFEIPDVPEKSEYL-EVKYSAEMPQLPQDLKGETFSHVFG 478

Query: 510  ARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSPSSSKI 569
               S+LELFL+ RKIKGP WL+V    + + +Q VSWCK E +   P  +      S   
Sbjct: 479  TNTSSLELFLMNRKIKGPCWLEVKK--STALNQPVSWCKVEAMALKPDLVNVIKDVSP-- 534

Query: 570  TLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGMLTHFTV 629
                PP+VV A ++KT  N K + NEI++ + +  +   +D         +P   +HF V
Sbjct: 535  ----PPLVVMAFSMKTMQNAKNHQNEIIAMAALVHHSFALDKAA-----PKPPFQSHFCV 585

Query: 630  IRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSDVLVGHNIS 689
            + K    IFP  F   +  +N+K       V ++ER LL   + ++HK+D D++VGHNI 
Sbjct: 586  VSKPKDCIFPYAFKEVIEKKNVKVE-----VAATERTLLGFFLAKVHKIDPDIIVGHNIY 640

Query: 690  GFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMSCVAGRLLC 749
            GF+L+VLL R   C+ P   WSK+GRL RS MPKL  R    GFG   A      GR++C
Sbjct: 641  GFELEVLLQRINVCKAPH--WSKIGRLKRSNMPKLGGRS---GFGERNA----TCGRMIC 691

Query: 750  DTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMELIEYGETDAWL 809
            D  + +++L++  SY L+ L +  L   R  +    +  M+  +  L+ L+E+   DA  
Sbjct: 692  DVEISAKELIRCKSYHLSELVQQILKTERVVIPMENIQNMYSESSQLLYLLEHTWKDAKF 751

Query: 810  SMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIVPDKFSNYA 869
             +++M  L+VLPL  Q+TN++GN+  +TL G R++R E+LLLH F++  YIVPDK     
Sbjct: 752  ILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFLLLHAFYENNYIVPDKQIFRK 811

Query: 870  KETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNKKAASYAGGLVLEPKKGLY 929
             + KL                    D +   D   + +KK +K  +YAGGLVL+PK G Y
Sbjct: 812  PQQKL-------------------GDEDEEIDGDTNKYKKGRKKGAYAGGLVLDPKVGFY 852

Query: 930  DKYILLLDFNSLYPSIIQEYNICFTTVERSSDDS-----------FPRLPS-SKTTGVLP 977
            DK+ILLLDFNSLYPSIIQE+NICFTTV+R + ++            P LP  S   G+LP
Sbjct: 853  DKFILLLDFNSLYPSIIQEFNICFTTVQRVASEAQKVTEDGEQEQIPELPDPSLEMGILP 912

Query: 978  ELLKKLVKLRREKKTWMKTASGLKRQ---QLDIEQQALKLTANSMYGCLGFSNSRFYAKP 1034
              ++KLV+ R++ K  MK    L      Q DI Q+ALKLTANSMYGCLGFS SRFYAKP
Sbjct: 913  REIRKLVERRKQVKQLMKQQD-LNPDLILQYDIRQKALKLTANSMYGCLGFSYSRFYAKP 971

Query: 1035 LAELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEVN 1094
            LA L+T +GREIL  T ++VQ  +NLEVIYGDTDSIMI +   ++ +   +  KV  EVN
Sbjct: 972  LAALVTYKGREILMHTKEMVQK-MNLEVIYGDTDSIMINTNSTNLEEVFKLGNKVKSEVN 1030

Query: 1095 KKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQ-FKDGTPYEVIERKGLDIVRRDWSLLAKD 1153
            K Y+ LEID+DG++K +LLLKKKKYAA+ V+   DG      E KGLDIVRRDW  LAKD
Sbjct: 1031 KLYKLLEIDIDGVFKSLLLLKKKKYAALVVEPTSDGNYVTKQELKGLDIVRRDWCDLAKD 1090

Query: 1154 LGDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDAK 1213
             G+F + QILS  S + +VE+I   L+++ E + NG V + ++ I K LTK P+ YPD K
Sbjct: 1091 TGNFVIGQILSDQSRDTIVENIQKRLIEIGENVLNGSVPVSQFEINKALTKDPQDYPDKK 1150

Query: 1214 NQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRARHPDELKQEQGT 1273
            + PHV VA  +  QG       GDT+ YVIC  Q GS+ +A+    RA  P++L Q+Q  
Sbjct: 1151 SLPHVHVALWINSQGGRK-VKAGDTVSYVIC--QDGSNLTASQ---RAYAPEQL-QKQDN 1203

Query: 1274 WLIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQ----HKSSEASDDPTS 1329
              ID  YYL+QQIHPV++R+C  I G     +A  LGLD ++F+    HK  E      +
Sbjct: 1204 LTIDTQYYLAQQIHPVVARICEPIDGIDAVLIATWLGLDPTQFRVHHYHKDEE------N 1257

Query: 1330 SLLFAGDDEESEKPTSSGTDESDYNFWRKLCCP-------KCFEN---GAG--------R 1371
              L  G  +         TDE  Y    +  CP         ++N   G+G        R
Sbjct: 1258 DALLGGPAQL--------TDEEKYRDCERFKCPCPTCGTENIYDNVFDGSGTDMEPSLYR 1309

Query: 1372 IS-----------AAMIANQVKRQAEKFVLMYYRGLLMCDDETCKHTTRSVSFRLVGDSE 1420
             S              ++N++     +F+  YY G L+C++ TC++ TR +  +    S 
Sbjct: 1310 CSNIDCKASPLTFTVQLSNKLIMDIRRFIKKYYDGWLICEEPTCRNRTRHLPLQF---SR 1366

Query: 1421 RGTVCPNYPRCNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKMEA-KSRIPIEKELIKI 1479
             G +CP   +    L  +Y++  LY QL ++ ++FD  C +EK+     +  ++K+    
Sbjct: 1367 TGPLCPACMKAT--LQPEYSDKSLYTQLCFYRYIFDAECALEKLTTDHEKDKLKKQFFTP 1424

Query: 1480 RPIVDL--AASTIQKIRDRCAFGWVKLQDL 1507
            + + D     +T ++   R  +  V L  L
Sbjct: 1425 KVLQDYRKLKNTAEQFLSRSGYSEVNLSKL 1454


>UniRef100_O89042 DNA polymerase alpha catalytic subunit [Rattus norvegicus]
          Length = 1451

 Score =  672 bits (1733), Expect = 0.0
 Identities = 435/1151 (37%), Positives = 634/1151 (54%), Gaps = 133/1151 (11%)

Query: 380  LFVWQGTLYQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQD 439
            ++V     + SCCV+VKN++R +Y +P          ++++ +  +   +P      ++D
Sbjct: 372  VWVESAKTHVSCCVMVKNIERTLYFLPRE--------MKIDLNTGKETATPIT----MKD 419

Query: 440  AVSDTKNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDL 499
               +  ++I+       +  F    V++ YAFE  D+P    Y+ ++ Y  +   LP +L
Sbjct: 420  VYEEFDSKIS---AKYKIMKFKSKIVEKNYAFEIPDVPEKSEYL-EVRYSAEVPQLPQNL 475

Query: 500  KGKSFCALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDI 559
            KG++F  + G   S+LELFL+ RKIKGP WL+V N    +  Q +SWCKFE +   P  +
Sbjct: 476  KGETFSHVFGTNTSSLELFLMNRKIKGPCWLEVKNPQLLN--QPISWCKFEAMALKPDLV 533

Query: 560  RASSPSSSKITLVNPPVVVTAINLKTTINEKQNINEIVS-ASVVSCNMVKIDTPMLASEW 618
                  S       PP+VV + ++KT  N + + +EI++ A++V  N      P      
Sbjct: 534  NVIKDVSP------PPLVVMSFSMKTMQNVQNHQHEIIAMAALVHHNFPLDKAP------ 581

Query: 619  KRPGMLTHFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKM 678
             +P   THF V+ K    IFP  F   +  +N++       V ++ER LL   + ++HK+
Sbjct: 582  PKPPFQTHFCVVSKPKDCIFPCAFKEVIKKKNMEVE-----VAATERTLLGFFLAKVHKL 636

Query: 679  DSDVLVGHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPA 738
            D D+LVGHNI GF+L+VLL R   C+VP   WSK+GRL RS MPKL  R    GFG   A
Sbjct: 637  DPDILVGHNICGFELEVLLQRINECKVP--FWSKIGRLRRSNMPKLGSRS---GFGERNA 691

Query: 739  IMSCVAGRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLME 798
                  GR++CD  +  ++L+   SY L+ L +  L   R  +    +  M+     L+ 
Sbjct: 692  ----TCGRMICDVEISVKELIHCKSYHLSELVQQILKTERIVIPTENIRNMYSEPSHLLY 747

Query: 799  LIEYGETDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKK 858
            L+E+   DA   +++M  L+VLPL  Q+TN++GN+  +TL G R++R E+LLLH F++  
Sbjct: 748  LLEHIWKDARFILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFLLLHAFYENN 807

Query: 859  YIVPDKFSNYAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNKKAASYAG 918
            YIVPDK        ++ ++      D+    D D N            +KK +K A+YAG
Sbjct: 808  YIVPDK--------QIFRKPQQKPGDEDEEIDGDTNK-----------YKKGRKKAAYAG 848

Query: 919  GLVLEPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSSDDSF-----------PRL 967
            GLVL+PK G YDK+ILLLDFNSLYPSIIQE+NICFTTV+R + ++            P L
Sbjct: 849  GLVLDPKVGFYDKFILLLDFNSLYPSIIQEFNICFTTVQRVASETLKATEDEEQEQIPEL 908

Query: 968  PSSKTT-GVLPELLKKLVKLRREKKTWMKTASGLKRQ---QLDIEQQALKLTANSMYGCL 1023
            P      G+LP  ++KLV+ R++ K  MK    L      Q DI Q+ALKLTANSMYGCL
Sbjct: 909  PDPNLDMGILPREIRKLVERRKQVKQLMKQQD-LNPDLVLQYDIRQKALKLTANSMYGCL 967

Query: 1024 GFSNSRFYAKPLAELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKAT 1083
            GFS SRFYAKPLA L+T +GREIL  T ++VQ  +NLEVIYGDTDSIMI +   ++ +  
Sbjct: 968  GFSYSRFYAKPLAALVTYKGREILMHTKEMVQK-MNLEVIYGDTDSIMINTNSTNLEEVF 1026

Query: 1084 SISKKVIQEVNKKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQ-FKDGTPYEVIERKGLDI 1142
             +  KV  EVNK Y+ LEID+DG++K +LLLKKKKYAA+ V+   DG      E KGLDI
Sbjct: 1027 KLGNKVKNEVNKLYKLLEIDIDGVFKSLLLLKKKKYAALVVEPTSDGNYITKQELKGLDI 1086

Query: 1143 VRRDWSLLAKDLGDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTL 1202
            VRRDW  LAKD G+F + QILS  S + +VE+I   L+++ E + NG V + ++ I K L
Sbjct: 1087 VRRDWCDLAKDTGNFVIGQILSDQSRDTIVENIQKRLIEIGENVLNGSVPVSQFEINKAL 1146

Query: 1203 TKPPEAYPDAKNQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRAR 1262
            TK P+ YPD K+ PHV VA  +  QG       GDT+ YVIC  Q GS+  AT    RA 
Sbjct: 1147 TKDPQDYPDKKSLPHVHVALWINSQGGRK-VKAGDTVSYVIC--QDGSNLPAT---QRAY 1200

Query: 1263 HPDELKQEQGTWLIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQHKSSE 1322
             P++L Q+Q    ID  YYL+QQIHPV++R+C  I G     +A  LGLD+++F  +  +
Sbjct: 1201 APEQL-QKQDNLAIDTQYYLAQQIHPVVARICEPIDGIDAVLIALWLGLDSTQF--RVHQ 1257

Query: 1323 ASDDPTSSLLFAGDDEESEKPTSSGTDESDYNFWRKL--CCPKC-----FEN---GAG-- 1370
               D  +  L  G         +  TDE  Y    K    CP C     ++N   G+G  
Sbjct: 1258 YHKDEENDALLGG--------PAQLTDEEKYKDCEKFKCLCPSCGTENIYDNVFEGSGMD 1309

Query: 1371 -------------RISAA----MIANQVKRQAEKFVLMYYRGLLMCDDETCKHTTRSVSF 1413
                         + S A     ++N++     + +  YY G L+C++ TC++  R +  
Sbjct: 1310 MEPSLNRCSNIDCKASPATFMVQLSNKLIMDIRRCIKKYYDGWLICEEPTCRNRIRRLPL 1369

Query: 1414 RLVGDSERGTVCPNYPRCNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKMEAKSRIPIE 1473
                 S  G +CP   +    L  +Y++  LY QL ++ ++FD  C +EK+    +  ++
Sbjct: 1370 HF---SRNGPLCPACMK--AVLRPEYSDKSLYTQLCFYRYIFDADCALEKLPEHEKDKLK 1424

Query: 1474 KELIKIRPIVD 1484
            K+    R + D
Sbjct: 1425 KQFFTPRVLQD 1435


>UniRef100_UPI000035F163 UPI000035F163 UniRef100 entry
          Length = 1451

 Score =  662 bits (1709), Expect = 0.0
 Identities = 440/1157 (38%), Positives = 622/1157 (53%), Gaps = 143/1157 (12%)

Query: 390  SCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISP-----ADFRKKLQDAVSDT 444
            SCCV V+N++R +Y +P                 +E R++P     +D    + D   + 
Sbjct: 372  SCCVTVRNIERTMYLLP-----------------REYRVNPKTGEVSDTPVGMMDVYQEF 414

Query: 445  KNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSF 504
             NE+++      +  +    V++ YAFE  D+ +   Y+ ++ Y  +  ALP DLK  +F
Sbjct: 415  -NELSEKFK---IMKYKSKKVEKNYAFEIPDVSSHGEYL-EVRYSAEFPALPSDLKASTF 469

Query: 505  CALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSP 564
              + G   S LE  L+ RKIKGP WL V+  +    SQ VSWCK E +   P  I     
Sbjct: 470  SHIFGTNTSFLEHLLLSRKIKGPCWLDVT--TPQRMSQPVSWCKVEALALKPDLISVIKD 527

Query: 565  SSSKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGML 624
                  LV PP+ V +I+LKT  N K   NEIVS + +  +  ++D          P   
Sbjct: 528  ------LVPPPLTVMSISLKTVQNPKTLHNEIVSLAALIHHQFQMDKAA-----PEPPYQ 576

Query: 625  THFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSDVLV 684
            +HF VI K    IFP  F   V  +N K       +  +ER LL   + ++HK+D DVLV
Sbjct: 577  SHFCVISKPSDCIFPYDFKEAVRKKNGKVE-----IAQTERTLLGFFLAKMHKIDPDVLV 631

Query: 685  GHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMSCVA 744
            GH+I GFDL+V+L R   C+VP   WSK+GRL R+ MPKL  R          A  S   
Sbjct: 632  GHDIFGFDLEVILQRISVCKVPH--WSKIGRLRRANMPKLGGRSAF-------AEKSATC 682

Query: 745  GRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMELIEYGE 804
            GRL+CD  + +++L++  SY LT L    L   R  V    +  ++  +  L+ L+E   
Sbjct: 683  GRLVCDVEISAKELIRCKSYHLTELTAHILKVERVTVPQENIRNLYSNSPHLLRLLELTW 742

Query: 805  TDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIVPDK 864
            TDA L +++M  L+VLPL  Q+TN++GN+  +TL G R++R E+LLLH FH+K YIVPDK
Sbjct: 743  TDAKLILQMMCELNVLPLALQITNIAGNVMSRTLMGGRSERNEFLLLHAFHEKNYIVPDK 802

Query: 865  FSNYAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNKKAASYAGGLVLEP 924
             S      K T+  +  G D+G                      K KK A+YAGGLVL+P
Sbjct: 803  PS-----FKKTQLEMAEGEDEGAVGKG-----------------KRKKKAAYAGGLVLDP 840

Query: 925  KKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSS-----------DDSFPRLP-SSKT 972
            K G YDK++LLLDFNSLYPSIIQE+NICFTTV+R +            +  P +P SS  
Sbjct: 841  KVGFYDKFVLLLDFNSLYPSIIQEFNICFTTVQREALNLQRKNEEEDQEEIPEIPDSSLE 900

Query: 973  TGVLPELLKKLVKLRREKKTWMK--TASGLKRQQLDIEQQALKLTANSMYGCLGFSNSRF 1030
             G+LP+ ++KLV+ R++ K  MK    +     Q DI Q+ALKLTANSMYGCLGFS SRF
Sbjct: 901  MGILPKEIRKLVERRKQVKQLMKQQDINPDAYLQYDIRQKALKLTANSMYGCLGFSYSRF 960

Query: 1031 YAKPLAELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSISKKVI 1090
            YAKPLA L+T +GREIL  T ++VQ  +NL+VIYGDTDSIMI +    + +   +  KV 
Sbjct: 961  YAKPLAALVTHKGREILMHTKEMVQ-KMNLDVIYGDTDSIMINTNSKSLEEVFKLGNKVK 1019

Query: 1091 QEVNKKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQ-FKDGTPYEVIERKGLDIVRRDWSL 1149
             EVNK Y+ LEID+DG++K +LLLKKKKYAA+ V+   DG      E KGLDIVRRDW  
Sbjct: 1020 AEVNKLYKLLEIDIDGVFKSLLLLKKKKYAALVVENHGDGRYTLKQELKGLDIVRRDWCD 1079

Query: 1150 LAKDLGDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTKPPEAY 1209
            LAK+ G++ + QILS  S + +VE+I   L+++ E++  G + L +Y I K L K P+ Y
Sbjct: 1080 LAKECGNYVIGQILSDQSRDVIVENIQKHLVEMGEKVAAGDIPLNQYEIHKALAKDPQDY 1139

Query: 1210 PDAKNQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRARHPDELKQ 1269
            PD K+ PHV VA  +  QG       GDT+ Y+IC       GS    + RA   ++L++
Sbjct: 1140 PDKKSLPHVHVALWINSQG-GRRVKAGDTVSYIIC-----KDGSTLAASQRAYTQEQLQK 1193

Query: 1270 EQGTWLIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQHKSSEASDDPTS 1329
            ++G  L D  YYL+QQ+HPV+SR+C  I+G     +A  LGLD S+F+ +     +D   
Sbjct: 1194 QEGLSL-DTQYYLAQQVHPVVSRICDPIEGIDGVLIATWLGLDPSQFRAQQQYQREDENH 1252

Query: 1330 SL--LFAGDDEESEKPTSSGTDESDYNFWRKLC-----CPKCFENGAGRISAAM------ 1376
             L       DEE  K      D  ++ F    C     C   FE     +  ++      
Sbjct: 1253 LLGVSLQLTDEERYK------DCENFTFTCPQCGTDNICDSVFEGTGLNLEPSLMRCCHI 1306

Query: 1377 ------------IANQVKRQAEKFVLMYYRGLLMCDDETCKHTTRSVSFRLVGDSERGTV 1424
                        I N++     + +  YY G L+C+D+ C++ TR +    +  S +G +
Sbjct: 1307 PCESRPIDYSVNICNKLLLDIRRHIKKYYAGWLVCEDQACQNRTRRLP---IAFSRQGPI 1363

Query: 1425 CPNYPRCNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKMEAKSRIPI-----EKEL--- 1476
            CP   R    L  +Y+E  LY QL ++  +FD      K++A  +  +     EKE+   
Sbjct: 1364 CPACSRAT--LRPEYSEKALYNQLCFYRFIFDWEAAFSKIQADEKSHVKNCNKEKEVYRR 1421

Query: 1477 IKIRPIVDLAASTIQKI 1493
            +K  P   LAAS+   I
Sbjct: 1422 LKEVPDKALAASSYSDI 1438


>UniRef100_Q7ZA56 DNA polymerase alpha catalytic subunit [Coprinus cinereus]
          Length = 1426

 Score =  662 bits (1709), Expect = 0.0
 Identities = 427/1149 (37%), Positives = 629/1149 (54%), Gaps = 113/1149 (9%)

Query: 390  SCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKD---VQESRISPADFRKKLQDAVSDTKN 446
            SCCV +  ++R +YA+P        + I  ++D   V E+   P D          D  +
Sbjct: 353  SCCVTIDGLERNLYALPRE------KRIDFDEDTGEVTETDEIPTD---------EDVLD 397

Query: 447  EIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSFCA 506
            +  +   ++ + S+    VKR YAF   D+P GE   +KI Y   +   P+ +   +   
Sbjct: 398  DFEQLRQNMKIKSYKTRFVKRNYAFGEKDVPRGETGWLKIVYHSLNPD-PMGVWSPNISH 456

Query: 507  LLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSPSS 566
            + G   SA E+F++KRKI GP WL++ N       + VSWC+FE  V  PKD+   S S 
Sbjct: 457  IFGTNTSAFEIFVLKRKIMGPCWLEIKN--PVVEFKGVSWCRFEASVADPKDVSPMSESL 514

Query: 567  SKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGMLTH 626
             +   V PP  V +++++T +N  +N  E+V AS  + + + ID    A   + P  +  
Sbjct: 515  DQAKEV-PPFTVMSLSVRTVVNHHENKREVVCASTRTWHNISIDDG--APPEQLPCSVQT 571

Query: 627  FTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSDVLVGH 686
            F  IR LD   FP  F +E   +     S     E S    L+ L+  ++K D D+++GH
Sbjct: 572  F--IRPLDR--FPPNFESETKKKTRGRFSPRRTSECS----LSLLLAAINKSDPDIIIGH 623

Query: 687  NISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMSCVAGR 746
               G  LDVLLHR +  +V    WS+LGR  RS  P + ++G    F         + GR
Sbjct: 624  EFLGVSLDVLLHRMKDLKVDH--WSRLGRFRRSKWPNIGKQGTNVRF---------LNGR 672

Query: 747  LLCDTYL-CSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKS----LMELIE 801
            L CD     ++ ++   ++SLT +  T L   R+++ P +       + S    +M  ++
Sbjct: 673  LTCDLASDAAKSMISSTTWSLTEMCSTHLGLERQDIDPDDTANYLDGSLSGPGKMMTFVQ 732

Query: 802  YGETDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIV 861
            + E DA   M +   + +LPLTRQLTNL+GN W KTL G RA+R EY+LLHEFH+ KYI 
Sbjct: 733  HCEMDAHYQMAIATKVQILPLTRQLTNLAGNAWNKTLNGGRAERNEYILLHEFHRLKYIC 792

Query: 862  PDKFSNYAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNKKAASYAGGLV 921
            PDK   Y K+T                       A+   DA +S  K++K    Y GGLV
Sbjct: 793  PDK--TYGKKT------------------VPKETADEEGDAPKSKAKRDK----YKGGLV 828

Query: 922  LEPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVE-----RSSDDSFPRLPSSKTTGVL 976
             EPK+GL+D YIL++DFNSLYPSIIQEYNI FTTV+      + ++  P  PS K  GVL
Sbjct: 829  FEPKRGLWDSYILVMDFNSLYPSIIQEYNIDFTTVDPPEVDENGEEKIPDPPSDKDKGVL 888

Query: 977  PELLKKLVKLRREKKTWMK--TASGLKRQQLDIEQQALKLTANSMYGCLGFSNSRFYAKP 1034
            P L+  LV  RR+ K+ MK  TA+  K  Q DI+QQALKLTANSMYGCLGF  SRFYA+P
Sbjct: 889  PRLIATLVNRRRQVKSLMKDRTATPAKLLQYDIKQQALKLTANSMYGCLGFEYSRFYARP 948

Query: 1035 LAELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEVN 1094
            LA L T +GREIL  T +L ++ LNL+VIYGDTDS+ + SG++D A+A   S    + VN
Sbjct: 949  LAALTTFKGREILTRTRELAES-LNLDVIYGDTDSVFVNSGVNDFAEALKTSAIFKKAVN 1007

Query: 1095 KKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQFKDGTPYEVIERKGLDIVRRDWSLLAKDL 1154
             +Y  LEIDLD +++R+LLL+KKKYAA+KV+    T  EV   KGLD+ RR++  L+K++
Sbjct: 1008 DQYNLLEIDLDCVFQRLLLLQKKKYAALKVEDGSRTSVEV---KGLDMKRREYCALSKEV 1064

Query: 1155 GDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDAKN 1214
              + L +ILSG S EDVVE+IH  L  + + +R+GQV LE +++ K L K PE YPDAK+
Sbjct: 1065 SQYVLARILSGDSTEDVVETIHEYLGTMSQNVRSGQVKLEDFIVFKRLGKNPEDYPDAKS 1124

Query: 1215 QPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRARHPDELKQEQGTW 1274
            QPHV VA R+K +G ++    GD IPY+ C  +G  S   T  A RARHPDE+++  G  
Sbjct: 1125 QPHVQVALRMKAKGQSA--RGGDVIPYIFCLGEGEESARTTQ-ADRARHPDEVRRGAGVV 1181

Query: 1275 LIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKFQHKSSE------ASDDPT 1328
             ID ++YL+ Q+ P I RLC +I+GT   RLA+CLGLD ++++  ++       + D   
Sbjct: 1182 KIDYEWYLAHQVLPPIERLCDAIEGTDRARLAECLGLDPNRYRTTTASDEKFFMSLDSQM 1241

Query: 1329 SSLLFAGDDEESEKPTSSGTDESDYNFWRKLCCPKCFENGAGRISA------AMIANQVK 1382
            S      D +  E    S   ++ +        P    +G   +S         +  Q++
Sbjct: 1242 SDAERFKDADPFEVRCKSCQGKTKFPLLHDRTIPLVRASGVTCLSCDKPIAGVNLQLQLE 1301

Query: 1383 RQAEKFVLMYYRGLLMCDDETCKHTTRSVSFRLVGDSERGTVCPNYPRCNGHLNRKYTEA 1442
             Q    +  YY G  +CD++TCK+ TR++          G  C   P C G ++ +Y++ 
Sbjct: 1302 VQIRAHISKYYEGWTVCDEQTCKNRTRAMGV-------YGKRCLK-PGCRGRVSFEYSDT 1353

Query: 1443 DLYKQLSYFCHVFDTVCYIEKMEAKSRIPIEKELIKI----RPIVDLAASTIQKIRDRCA 1498
             LY QL Y+ ++FD     + ++A      E+E++ +      +++  +  ++K  ++C 
Sbjct: 1354 KLYNQLRYYKYLFDRE---KALKAARGTGSEEEVLAVVGSQATLLNNLSDVVEKYLNQCG 1410

Query: 1499 FGWVKLQDL 1507
              WV L  +
Sbjct: 1411 RRWVDLNSI 1419


>UniRef100_Q6DRM6 DNA polymerase alpha [Brachydanio rerio]
          Length = 1389

 Score =  661 bits (1705), Expect = 0.0
 Identities = 435/1113 (39%), Positives = 612/1113 (54%), Gaps = 124/1113 (11%)

Query: 390  SCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESRISPADFRKKLQDAVSDTKNEIA 449
            SCCV VKN++R +Y +P                 +E +++ A   K +   + D   E  
Sbjct: 360  SCCVAVKNIERTMYLLP-----------------REHKVNLATGEKGVAVGMMDVYKEFN 402

Query: 450  KHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSFCALLG 509
            +      +  F   PV + YAFE  DIP+   Y+ ++ Y  +  +LP DLKG +F  + G
Sbjct: 403  EISEKFKIMKFKSKPVTKNYAFEIPDIPSQSEYL-EVKYSAEIPSLPSDLKGTTFSHVFG 461

Query: 510  ARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSPSSSKI 569
               S+LE FL+ RKI+GP WL V+      ++Q +SWCK E +      I      S   
Sbjct: 462  TNTSSLEHFLLNRKIRGPCWLDVTTPQL--SNQPISWCKVEAVAQKSDLISVVKDLSP-- 517

Query: 570  TLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGMLTHFTV 629
                PP+VV +I+LKT  N K + NEIVS + +  +   +D         RP   THF  
Sbjct: 518  ----PPLVVMSISLKTVQNPKTHQNEIVSIAALVHHTFPLDKAP-----PRPPFQTHFCE 568

Query: 630  IRKLDGNIFPMGFNTEVTDRNIKAGSNV-LCVESSERALLNRLMLQLHKMDSDVLVGHNI 688
                  +  P+  N ++      AGS++ +     ERALL     ++HK+D DVL+GH+I
Sbjct: 569  ------SDTPIKNNFQIAS----AGSSLKIRTLFYERALLGFFPFKMHKIDPDVLLGHDI 618

Query: 689  SGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMPKLDRRGKTFGFGADPAIMSCVAGRLL 748
             GFDL+VLL R   C+VP   WSK+GRL R+ MPKL  R    GF    A  S   GRL+
Sbjct: 619  FGFDLEVLLQRINVCKVPH--WSKIGRLRRANMPKLGGRS---GF----AEKSATCGRLV 669

Query: 749  CDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKS-LMELIEYGETDA 807
            CD  + +++L++  SY+LT L    L   R  V P  +    Q   + L+ L+E    DA
Sbjct: 670  CDIEISAKELIRCKSYNLTELVSQILKAERPVVPPENISTFLQVDSTHLLYLLELTWMDA 729

Query: 808  WLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIVPDKFSN 867
             L +++M  L+VLPL  Q+TN++GN+  +TL G R++R EYLLLH FH++ +IVPDK   
Sbjct: 730  KLILQIMCELNVLPLALQITNIAGNVMSRTLMGGRSERNEYLLLHAFHERDFIVPDK--- 786

Query: 868  YAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNKKAASYAGGLVLEPKKG 927
                    K +   G D+               D+ +    K +K A+YAGGLVL+PK G
Sbjct: 787  ----QFFKKAQQDLGEDE-------------EGDSGKGKSNKTRKKAAYAGGLVLDPKVG 829

Query: 928  LYDKYILLLDFNSLYPSIIQEYNICFTTVERSS----------DDSFPRLPS-SKTTGVL 976
             YDK+ILLLDFNSLYPSIIQE+NICFTTVER +          +D  P LP  S   G+L
Sbjct: 830  FYDKFILLLDFNSLYPSIIQEFNICFTTVERGATNTRKKTEEDEDEIPELPDQSLEMGIL 889

Query: 977  PELLKKLVKLRREKKTWMKTASGLKRQ---QLDIEQQALKLTANSMYGCLGFSNSRFYAK 1033
            P+ ++KLV+ RR+ K  MK    L      Q DI Q+ALKLTANSMYGCLGFS SRFYAK
Sbjct: 890  PKEIRKLVERRRQVKQLMKEPD-LNPDLYLQYDIRQKALKLTANSMYGCLGFSFSRFYAK 948

Query: 1034 PLAELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEV 1093
            PLA L+T +GREIL  T ++VQ  +NLEVIYGDTDSIMI +   ++ +   +  KV  EV
Sbjct: 949  PLAALVTHKGREILMHTKEMVQR-MNLEVIYGDTDSIMINTNSTNLEEVFKLGNKVKSEV 1007

Query: 1094 NKKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQFK-DGTPYEVIERKGLDIVRRDWSLLAK 1152
            NK Y+ LEID+DG++K +LLLKKKKYAA+ V+ + DG      E KGLDIVRRDW  LAK
Sbjct: 1008 NKLYKLLEIDIDGVFKSLLLLKKKKYAALMVEPQGDGKYTTKQELKGLDIVRRDWCDLAK 1067

Query: 1153 DLGDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDA 1212
            + G++ + QILS  + + ++E+I   L+++ E++ NG + L  + I K+LTK P+ YPD 
Sbjct: 1068 ECGNYVIGQILSDQNRDTIIENIQKHLIEIGEKVANGNIPLNMFEIHKSLTKEPQDYPDK 1127

Query: 1213 KNQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSATGIALRARHPDELKQEQG 1272
            K+ PHV VA  +  QG       GDT+ YVIC       GS    + RA   ++L+++ G
Sbjct: 1128 KSLPHVHVALWINSQG-GKKVKAGDTVSYVIC-----QDGSNLAASQRAYTLEQLQKQPG 1181

Query: 1273 TWLIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTSKF---QHKSSEASDDPTS 1329
              L D  YYLSQQ+HPV+ R+C  I+G     +A  LGLD S F   Q +  + +DD   
Sbjct: 1182 LNL-DTQYYLSQQVHPVVGRICEPIEGIDAVLIATWLGLDPSHFRAQQQQREDEADDFLG 1240

Query: 1330 SLLFAGDDE---ESEKPTSSGTDESDYNFW--------------RKLCC-PKCFENGAGR 1371
            +     D+E   + E+ T +  D    N +               K CC   C   G+  
Sbjct: 1241 APAQLTDEERYRDCERFTFTCPDCGTENIYDNVFEGTGSTLQLSLKSCCHVPC--GGSPM 1298

Query: 1372 ISAAMIANQVKRQAEKFVLMYYRGLLMCDDETCKHTTRSVSFRLVGDSERGTVCPNYPRC 1431
                 I N+++    + +  YY G L+C+D+ C++  R +    +  S  G +CP   R 
Sbjct: 1299 DHQVQIGNKLQLDIRRHIRRYYSGWLLCEDQACRNRIRRLP---IAFSRSGPICPACLRS 1355

Query: 1432 NGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKM 1464
               L  +Y+E  LY QLS++ ++FD    I K+
Sbjct: 1356 T--LKPEYSEKALYNQLSFYRYIFDWEYAINKV 1386


>UniRef100_Q7Z081 DNA polymerase catalytic subunit alpha [Stylonychia lemnae]
          Length = 1514

 Score =  650 bits (1676), Expect = 0.0
 Identities = 412/1165 (35%), Positives = 620/1165 (52%), Gaps = 132/1165 (11%)

Query: 377  GYSLFVWQGTLYQ-------SCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESR-- 427
            G  LF++ G +YQ       SC + V  MQR +YA+P          +  E++ Q  R  
Sbjct: 377  GADLFIF-GKIYQPEINQYVSCSMKVNGMQREIYALPKMQKGKARGTLTREEENQLVRGV 435

Query: 428  -ISPADFRKKLQDAVSDTKNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKI 486
             +   D RKK                   G++ +   PV RKYAFE   I  GE+  +KI
Sbjct: 436  QLELEDIRKKRFQ----------------GITKWRCKPVTRKYAFEMP-IQHGEHLFLKI 478

Query: 487  NYLFKDTALPVDLKGKSFCALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSW 546
             Y      LP  ++G +F  L G+  S LELF++KRKIKGP W+ + N    +  ++ +W
Sbjct: 479  KYDATFIPLPSTVQGNTFECLFGSNQSMLELFILKRKIKGPCWMTIKNPKKVTDFKK-TW 537

Query: 547  CKFEVIVDSPKDIRASSPSSSKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNM 606
            C+ E+ +D+PK+   +    +K  +  PP+       KT    + N NEI   S +  N 
Sbjct: 538  CRQEIEIDNPKNAEVTLDDLNKTDI--PPLTSLTFAFKTA-RSQNNTNEIAMISCLVHNN 594

Query: 607  VKIDTPMLASEWKRPGMLTHFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERA 666
            V  + P    +++       FT++RKLDG   P  F     D+ ++     +   ++ER 
Sbjct: 595  VNQEGPSQTDKFQT------FTLVRKLDGKPMPFDF-----DQKLRQKKENIQYFTNERQ 643

Query: 667  LLNRLMLQLHKMDSDVLVGHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMP--KL 724
            +++  + ++ ++D D++V HN+ G   D+LL R Q  ++  + WS++GR  +  +P  K 
Sbjct: 644  MIDLFVTRIFQIDPDLIVAHNLCGGIFDLLLARIQILKI--NHWSRIGRFKKGNIPTKKF 701

Query: 725  DRRGKTFGFGADPAIMSCVAGRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPH 784
            D  G  +G G+         GRLL DT+L +++L++E +Y LTHL K QL + R++    
Sbjct: 702  DTGGANYG-GSQWIPRQVTCGRLLVDTFLSAKELIRETNYDLTHLTKVQLKKDRQDFDDD 760

Query: 785  EVPKMFQTAKSLMELIEYGETDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQ 844
             +P+ +  ++ + +LIE+ E D++ +  LM +LS++PLT+QLTN++GNLW ++LQ ARA+
Sbjct: 761  LLPQFYLASERIFQLIEHSEKDSYYTFMLMLHLSIIPLTKQLTNIAGNLWFRSLQNARAE 820

Query: 845  RVEYLLLHEFHKKKYIVPDKFSNYAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASE 904
            R E LLLHEF KKK+I+PDK    AK+ +                   + D    ND   
Sbjct: 821  RNEMLLLHEFKKKKFILPDKKPPNAKDLRR----------------GFMGDEYEENDTKG 864

Query: 905  SDHKKNK-KAASYAGGLVLEPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERS---- 959
               K  K K A YAGGLV+EPK G YD  ILLLDFNSLYPSIIQEYN+CFTTV R     
Sbjct: 865  GGKKGGKRKKAKYAGGLVIEPKAGFYDNIILLLDFNSLYPSIIQEYNLCFTTVNRRPTKN 924

Query: 960  ---------------------SDDSFPRLPSSKTTGVLPELLKKLVKLRREKKTWMKTAS 998
                                  D   P    +    VLP +L+ LV+ R+  K  MK   
Sbjct: 925  YDGSELKNQFKSADNAEGDEVEDVDLPDKNVNIXDAVLPNVLRDLVQKRKAVKEKMKNEK 984

Query: 999  G-LKRQQLDIEQQALKLTANSMYGCLGFSNSRFYAKPLAELITLQGREILQSTVDLVQNN 1057
              +K QQL+I Q+A+KLTANSMYGCLGFS+SRF+A  +A LIT  GRE L  T D+ +N 
Sbjct: 985  DQVKLQQLEIRQKAIKLTANSMYGCLGFSSSRFHASAIAALITKTGRETLLRTKDIAENK 1044

Query: 1058 LNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEVNKKYRCLEIDLDGLYKRMLLLKKK 1117
            L   V+YGDTDSIMI +G + + ++  + KK+  EVN  Y+CLEI++DG++K +LLLKKK
Sbjct: 1045 LGFNVVYGDTDSIMINTGTNQLQQSLEMGKKLKVEVNCLYKCLEIEIDGVFKSLLLLKKK 1104

Query: 1118 KYAAVKVQFKDGTPYEVI-ERKGLDIVRRDWSLLAKDLGDFCLTQILSGGSCEDVVESIH 1176
            KYAA++ +       +VI E KGLD+VRRDW  L+K +G++ L+QILSG   EDVV +++
Sbjct: 1105 KYAALRYEGVGSNEVKVIQEMKGLDMVRRDWCPLSKSIGNYVLSQILSGKQREDVVFNLN 1164

Query: 1177 NSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDAKNQPHVLVAQRLKQQGYTSGCSVG 1236
              L  + E+M++ ++ L++++ITK LT+    Y D K QPHV VAQRLK QG +    V 
Sbjct: 1165 EYLSDIGEKMKSNRITLDQFIITKQLTRAISEYSDIKGQPHVAVAQRLKNQGKSEADLVN 1224

Query: 1237 DTIPYVICCEQGGSSGSATGIALRARHPDELKQEQGTWLIDIDYYLSQQIHPVISRLCAS 1296
            + IPYVI  +   ++ S   ++ +A HPDEL   +G   +DID+Y++ QI P I+RL   
Sbjct: 1225 NFIPYVIGAQAFDTAKSNPQLSDKAYHPDELLSSKGKITLDIDWYITTQILPPITRLIEH 1284

Query: 1297 IQGTSPERLADCLGLDTSKFQHKSSEASDDPTSSLLFAGDDEES-EKPTSSGTDESDYNF 1355
            I G + E +A CLG+D  K+++ S + + D        GDD  S + P      E     
Sbjct: 1285 IDGINIEFVAQCLGVDPKKYKYHSEKKNTDE------IGDDGGSIQNPILQTETEKSLKH 1338

Query: 1356 WR----KLCCPKCFEN--------------------GAGRISAAMIANQVKRQAEKFVLM 1391
                  K+ CP C  N                       +I    + N+V    ++ + +
Sbjct: 1339 RSIAELKVKCPSCTHNYDFPGIYQEGKDVSGLICTKCNAKIPEKYVMNRVNLFLKQLLAL 1398

Query: 1392 YYRGLLMCDDETCKHTTRSVSFRLVGDSERGTVCPNYPRCNGHLNRKYTEADLYKQLSYF 1451
            YY+G   C + +CK  TR + +           C N   C G +  +Y+E      L Y 
Sbjct: 1399 YYQGKYECQEPSCKSMTRQLLYH--------NKCVNL-TCKGKMVPEYSEHQTNDTLRYL 1449

Query: 1452 CHVFDTVCYIEKMEAKSRIPIEKEL 1476
              +F+   ++ +      + +E ++
Sbjct: 1450 QGLFNIKKHLHENSKNDSLKVETDI 1474


>UniRef100_Q7Z083 DNA polymerase catalytic subunit alpha [Stylonychia lemnae]
          Length = 1514

 Score =  649 bits (1674), Expect = 0.0
 Identities = 412/1165 (35%), Positives = 621/1165 (52%), Gaps = 132/1165 (11%)

Query: 377  GYSLFVWQGTLYQ-------SCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESR-- 427
            G  LF++ G +YQ       SC + V  MQR +YA+P          +  E++ Q  R  
Sbjct: 377  GADLFIF-GKIYQPEINQYVSCSMKVNGMQREIYALPKMQKGKARGTLTREEENQLVRGV 435

Query: 428  -ISPADFRKKLQDAVSDTKNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKI 486
             +   D RKK                   G++ +   PV RKYAFE   I  GE+  +KI
Sbjct: 436  QLELEDIRKKRFQ----------------GITKWRCKPVTRKYAFEMP-IXHGEHLFLKI 478

Query: 487  NYLFKDTALPVDLKGKSFCALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSW 546
             Y      LP  ++G +F  L G+  S LELF++KRKIKGP W+ + N    +  ++ +W
Sbjct: 479  KYDATFIPLPSTVQGNTFECLFGSNQSMLELFILKRKIKGPCWMTIKNPKKVTDFKK-TW 537

Query: 547  CKFEVIVDSPKDIRASSPSSSKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNM 606
            C+ E+ +D+PK+   +    +K  +  PP+       KT    + N NEI   S +  N 
Sbjct: 538  CRQEIEIDNPKNAEVTLDDLNKTDI--PPLTSLTFAFKTA-RSQNNTNEIAMISCLVHNN 594

Query: 607  VKIDTPMLASEWKRPGMLTHFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERA 666
            V  + P    +++       FT++RKLDG   P  F     D+ ++     +   ++ER 
Sbjct: 595  VNQEGPSQTDKFQT------FTLVRKLDGKPMPFDF-----DQKLRQKKENIQYFTNERQ 643

Query: 667  LLNRLMLQLHKMDSDVLVGHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMP--KL 724
            +++  + ++ ++D D++V HN+ G   D+LL R Q  ++  + WS++GR  +  +P  K 
Sbjct: 644  MIDLFVTRIFQIDPDLIVAHNLCGGIFDLLLARIQILKI--NHWSRIGRFKKGNIPTKKF 701

Query: 725  DRRGKTFGFGADPAIMSCVAGRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPH 784
            D  G  +G G+         GRLL DT+L +++L++E +Y LTHL K QL + R++    
Sbjct: 702  DTGGANYG-GSQWIPRQVTCGRLLVDTFLSAKELIRETNYDLTHLTKVQLKKDRQDFDDD 760

Query: 785  EVPKMFQTAKSLMELIEYGETDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQ 844
             +P+ +  ++ + +LIE+ E D++ +  LM +LS++PLT+QLTN++GNLW ++LQ ARA+
Sbjct: 761  LLPQFYLASERIFQLIEHSEKDSYYTFMLMLHLSIIPLTKQLTNIAGNLWFRSLQNARAE 820

Query: 845  RVEYLLLHEFHKKKYIVPDKFSNYAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASE 904
            R E LLLHEF KKK+I+PDK    AK+ +                   + D    ND   
Sbjct: 821  RNEMLLLHEFKKKKFILPDKKPPNAKDLRR----------------GFMGDEYEENDTKG 864

Query: 905  SDHKKNK-KAASYAGGLVLEPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSSDDS 963
               K  K K A YAGGLV+EPK G YD  ILLLDFNSLYPSIIQEYN+CFTTV R    +
Sbjct: 865  GGKKGGKRKKAKYAGGLVIEPKAGFYDNIILLLDFNSLYPSIIQEYNLCFTTVNRRPTKN 924

Query: 964  FPR----------------------LPSSKTT---GVLPELLKKLVKLRREKKTWMKTAS 998
            +                        LP         VLP +L+ LV+ R+  K  MK   
Sbjct: 925  YDGSELKNQFKSADNAEGDEVEDVDLPDKNVNIKDAVLPNVLRDLVQKRKAVKEKMKNEK 984

Query: 999  G-LKRQQLDIEQQALKLTANSMYGCLGFSNSRFYAKPLAELITLQGREILQSTVDLVQNN 1057
              +K QQL+I Q+A+KLTANSMYGCLGFS+SRF+A  +A LIT  GRE L  T D+ +N 
Sbjct: 985  DQVKLQQLEIRQKAIKLTANSMYGCLGFSSSRFHASAIAALITKTGRETLLRTKDIAENK 1044

Query: 1058 LNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEVNKKYRCLEIDLDGLYKRMLLLKKK 1117
            L   V+YGDTDSIMI +G + + ++  + KK+  EVN  Y+CLEI++DG++K +LLLKKK
Sbjct: 1045 LGFNVVYGDTDSIMINTGTNQLQQSLEMGKKLKVEVNCLYKCLEIEIDGVFKSLLLLKKK 1104

Query: 1118 KYAAVKVQFKDGTPYEVI-ERKGLDIVRRDWSLLAKDLGDFCLTQILSGGSCEDVVESIH 1176
            KYAA++ +       +VI E KGLD+VRRDW  L+K +G++ L+QILSG   EDVV +++
Sbjct: 1105 KYAALRYEGVGSNEVKVIQEMKGLDMVRRDWCPLSKSIGNYVLSQILSGKQREDVVFNLN 1164

Query: 1177 NSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDAKNQPHVLVAQRLKQQGYTSGCSVG 1236
              L  + E+M++ ++ L++++ITK LT+    Y D K QPHV VAQRLK QG +    V 
Sbjct: 1165 EYLSDIGEKMKSNRITLDQFIITKQLTRAISEYSDIKGQPHVAVAQRLKNQGKSEADLVN 1224

Query: 1237 DTIPYVICCEQGGSSGSATGIALRARHPDELKQEQGTWLIDIDYYLSQQIHPVISRLCAS 1296
            + IPYVI  +   ++ S   ++ +A HPDEL   +G   +DID+Y++ QI P I+RL   
Sbjct: 1225 NFIPYVIGAQAFDTAKSNPQLSDKAYHPDELLSSKGKITLDIDWYITTQILPPITRLIEH 1284

Query: 1297 IQGTSPERLADCLGLDTSKFQHKSSEASDDPTSSLLFAGDDEES-EKPTSSGTDESDYNF 1355
            I G + E +A CLG+D  K+++ S + + D        GDD  S + P      E     
Sbjct: 1285 IDGINIEFVAQCLGVDPKKYKYHSEKKNTDE------IGDDGGSIQNPILQTETEKSLKH 1338

Query: 1356 WR----KLCCPKCFEN--------------------GAGRISAAMIANQVKRQAEKFVLM 1391
                  K+ CP C  N                       +I    + N+V    ++ + +
Sbjct: 1339 RSIAELKVKCPSCTHNYDFPGIYQEGKDVSGLICTKCNAKIPEKYVMNRVNLFLKQLLAL 1398

Query: 1392 YYRGLLMCDDETCKHTTRSVSFRLVGDSERGTVCPNYPRCNGHLNRKYTEADLYKQLSYF 1451
            YY+G   C + +CK  TR + +           C N   C G +  +Y+E      L Y 
Sbjct: 1399 YYQGKYECQEPSCKSMTRQLLYH--------NKCVNL-TCKGKMVPEYSEHQTNDTLRYL 1449

Query: 1452 CHVFDTVCYIEKMEAKSRIPIEKEL 1476
              +F+   ++ +      + +E ++
Sbjct: 1450 QGLFNIKKHLHENSKNDSLKVETDI 1474


>UniRef100_Q7Z080 DNA polymerase catalytic subunit alpha [Stylonychia lemnae]
          Length = 1514

 Score =  649 bits (1673), Expect = 0.0
 Identities = 407/1147 (35%), Positives = 613/1147 (52%), Gaps = 124/1147 (10%)

Query: 388  YQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESR---ISPADFRKKLQDAVSDT 444
            Y SC + V  MQR +YA+P          +  E++ Q  R   +   D RKK        
Sbjct: 394  YVSCSMKVNGMQREIYALPKMQKGKARGTLTREEENQLVRGVQLELEDIRKKRFQ----- 448

Query: 445  KNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSF 504
                       G++ +   PV RKYAFE   I  GE+  +KI Y      LP  ++G +F
Sbjct: 449  -----------GITKWRCKPVTRKYAFEMP-IQHGEHLFLKIKYDATFIPLPSTVQGNTF 496

Query: 505  CALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSP 564
              L G+  S LELF++KRKIKGP W+ + N    +  ++ +WC+ E+ +D+PK+   +  
Sbjct: 497  ECLFGSNQSMLELFILKRKIKGPCWMTIKNPKKVTDFKK-TWCRQEIEIDNPKNAEVTLD 555

Query: 565  SSSKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGML 624
              +K  +  PP+       KT    + N NEI   S +  N V  + P    +++     
Sbjct: 556  DLNKTDI--PPLTSLTFAFKTA-RSQNNTNEIAMISCLVHNNVNQEGPSQTDKFQT---- 608

Query: 625  THFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSDVLV 684
              FT++RKLDG   P  F     D+ ++     +   ++ER +++  + ++ ++D D++V
Sbjct: 609  --FTLVRKLDGKPMPFDF-----DQKLRQKKENIQYFTNERQMIDLFVTRIFQIDPDLIV 661

Query: 685  GHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMP--KLDRRGKTFGFGADPAIMSC 742
             HN+ G   D+LL R Q  ++  + WS++GR  +  +P  K D  G  +G G+       
Sbjct: 662  AHNLCGGIFDLLLARIQILKI--NHWSRIGRFKKGNIPTKKFDTGGANYG-GSQWIPRQV 718

Query: 743  VAGRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMELIEY 802
              GRLL DT+L +++L++E +Y LTHL K QL + R++     +P+ +  ++ + +LIE+
Sbjct: 719  TCGRLLVDTFLSAKELIRETNYDLTHLTKVQLKKDRQDFDDDLLPQFYLASERIFQLIEH 778

Query: 803  GETDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIVP 862
             E D++ +  LM +LS++PLT+QLTN++GNLW ++LQ ARA+R E LLLHEF KKK+I+P
Sbjct: 779  SEKDSYYTFMLMLHLSIIPLTKQLTNIAGNLWFRSLQNARAERNEMLLLHEFKKKKFILP 838

Query: 863  DKFSNYAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNK-KAASYAGGLV 921
            DK    AK+ +                   + D    ND      K  K K A YAGGLV
Sbjct: 839  DKKPPNAKDLRR----------------GFMGDEYEENDTKGGGKKGGKRKKAKYAGGLV 882

Query: 922  LEPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSSDDSFPR--------------- 966
            +EPK G YD  ILLLDFNSLYPSIIQEYN+CFTTV R    ++                 
Sbjct: 883  IEPKAGFYDNIILLLDFNSLYPSIIQEYNLCFTTVNRRPTKNYDGSELKNQYKSADNAEG 942

Query: 967  -------LPSSKTT---GVLPELLKKLVKLRREKKTWMKTASG-LKRQQLDIEQQALKLT 1015
                   LP         VLP +L+ LV+ R+  K  MK     +K QQL+I Q+A+KLT
Sbjct: 943  DEVEDVDLPDKNVNIKDAVLPNVLRDLVQKRKAVKEKMKNEKDQVKLQQLEIRQKAIKLT 1002

Query: 1016 ANSMYGCLGFSNSRFYAKPLAELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSG 1075
            ANSMYGCLGFS+SRF+A  +A LIT  GRE L  T D+ +N L   V+YGDTDSIMI +G
Sbjct: 1003 ANSMYGCLGFSSSRFHASAIAALITKTGRETLLRTKDIAENKLGFNVVYGDTDSIMINTG 1062

Query: 1076 LDDIAKATSISKKVIQEVNKKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQFKDGTPYEVI 1135
             + + ++  + KK+  EVN  Y+CLEI++DG++K +LLLKKKKYAA++ +       +VI
Sbjct: 1063 TNQLQQSLEMGKKLKVEVNCLYKCLEIEIDGVFKSLLLLKKKKYAALRYEGVGSNEVKVI 1122

Query: 1136 -ERKGLDIVRRDWSLLAKDLGDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALE 1194
             E KGLD+VRRDW  L+K +G++ L+QILSG   EDVV +++  L  + E+M++ ++ L+
Sbjct: 1123 QEMKGLDMVRRDWCPLSKSIGNYVLSQILSGKQREDVVFNLNEYLSDIGEKMKSNRITLD 1182

Query: 1195 KYVITKTLTKPPEAYPDAKNQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSA 1254
            +++ITK LT+    Y D K QPHV VAQRLK QG +    V + IPYVI  +   ++ S 
Sbjct: 1183 QFIITKQLTRAISEYSDIKGQPHVAVAQRLKNQGKSEADLVNNFIPYVIGAQAFDTAKSN 1242

Query: 1255 TGIALRARHPDELKQEQGTWLIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTS 1314
              ++ +A HPDEL   +G   +DID+Y++ QI P I+RL   I G + E +A CLG+D  
Sbjct: 1243 PQLSDKAYHPDELLSSKGKITLDIDWYITTQILPPITRLIEHIDGINIEFVAQCLGVDPK 1302

Query: 1315 KFQHKSSEASDDPTSSLLFAGDDEES-EKPTSSGTDESDYNFWR----KLCCPKCFEN-- 1367
            K+++ S + + D        GDD  S + P      E           K+ CP C  N  
Sbjct: 1303 KYKYHSEKKNTDE------IGDDGGSIQNPILQTETEKSLKHRSIAELKVKCPSCTHNYD 1356

Query: 1368 ------------------GAGRISAAMIANQVKRQAEKFVLMYYRGLLMCDDETCKHTTR 1409
                                 +I    + N+V    ++ + +YY+G   C + +CK  TR
Sbjct: 1357 FPGIYQEGKDVSGLICTKCNAKIPEKYVMNRVNLFLKQLLALYYQGKYECQEPSCKSMTR 1416

Query: 1410 SVSFRLVGDSERGTVCPNYPRCNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKMEAKSR 1469
             + +           C N   C G +  +Y+E      L Y   +F+   ++ +      
Sbjct: 1417 QLLYH--------NKCVNL-TCKGKMVPEYSEHQTNDTLRYLQGLFNIKKHLHENSKNDS 1467

Query: 1470 IPIEKEL 1476
            + +E ++
Sbjct: 1468 LKVETDI 1474


>UniRef100_Q7Z084 DNA polymerase catalytic subunit alpha [Stylonychia lemnae]
          Length = 1514

 Score =  648 bits (1672), Expect = 0.0
 Identities = 412/1165 (35%), Positives = 620/1165 (52%), Gaps = 132/1165 (11%)

Query: 377  GYSLFVWQGTLYQ-------SCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESR-- 427
            G  LF++ G +YQ       SC + V  MQR +YA+P          +  E++ Q  R  
Sbjct: 377  GADLFIF-GKIYQPEINQYVSCSMKVNGMQREIYALPKMQKGKARGTLTREEENQLVRGV 435

Query: 428  -ISPADFRKKLQDAVSDTKNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKI 486
             +   D RKK                   G++ +   PV RKYAFE   I  GE+  +KI
Sbjct: 436  QLELEDIRKKRFQ----------------GITKWRCKPVTRKYAFEMP-IQHGEHLFLKI 478

Query: 487  NYLFKDTALPVDLKGKSFCALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSW 546
             Y      LP  ++G +F  L G+  S LELF++KRKIKGP W+ + N    +  ++ +W
Sbjct: 479  KYDATFIPLPSTVQGNTFECLFGSNQSMLELFILKRKIKGPCWMTIKNPKKVTDFKK-TW 537

Query: 547  CKFEVIVDSPKDIRASSPSSSKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNM 606
            C+ E+ +D+PK+   +    +K  +  PP+       KT    + N NEI   S +  N 
Sbjct: 538  CRQEIEIDNPKNAEVTLDDLNKTDI--PPLTSLTFAFKTA-RSQNNTNEIAMISCLVHNN 594

Query: 607  VKIDTPMLASEWKRPGMLTHFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERA 666
            V  + P    +++       FT++RKLDG   P  F     D+ ++     +   ++ER 
Sbjct: 595  VNQEGPSQTDKFQT------FTLVRKLDGKPMPFDF-----DQKLRQKKENIQYFTNERQ 643

Query: 667  LLNRLMLQLHKMDSDVLVGHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMP--KL 724
            +++  + ++ ++D D++V HN+ G   D+LL R Q  ++  + WS++GR  +  +P  K 
Sbjct: 644  MIDLFVTRIFQIDPDLIVAHNLCGGIFDLLLARIQILKI--NHWSRIGRFKKGNIPTKKF 701

Query: 725  DRRGKTFGFGADPAIMSCVAGRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPH 784
            D  G  +G G+         GRLL DT+L +++L++E +Y LTHL K QL + R++    
Sbjct: 702  DTGGANYG-GSQWIPRQVTCGRLLVDTFLSAKELIRETNYDLTHLTKVQLKKDRQDFDDD 760

Query: 785  EVPKMFQTAKSLMELIEYGETDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQ 844
             +P+ +  ++ + +LIE+ E D++ +  LM +LS++PLT+QLTN++GNLW ++LQ ARA+
Sbjct: 761  LLPQFYLASERIFQLIEHSEKDSYYTFMLMLHLSIIPLTKQLTNIAGNLWFRSLQNARAE 820

Query: 845  RVEYLLLHEFHKKKYIVPDKFSNYAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASE 904
            R E LLLHEF KKK+I+PDK    AK+ +                   + D    ND   
Sbjct: 821  RNEMLLLHEFKKKKFILPDKKPPNAKDLRR----------------GFMGDEYEENDTKG 864

Query: 905  SDHKKNK-KAASYAGGLVLEPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSSDDS 963
               K  K K A YAGGLV+EPK G YD  ILLLDFNSLYPSIIQEYN CFTTV R    +
Sbjct: 865  GGKKGGKRKKAKYAGGLVIEPKAGFYDNIILLLDFNSLYPSIIQEYNXCFTTVNRRPTKN 924

Query: 964  FPR----------------------LPSSKTT---GVLPELLKKLVKLRREKKTWMKTAS 998
            +                        LP         VLP +L+ LV+ R+  K  MK   
Sbjct: 925  YDGSELKNQFKSADNAEGDEVEDVDLPDKNVNIKDAVLPNVLRDLVQKRKAVKEKMKNEK 984

Query: 999  G-LKRQQLDIEQQALKLTANSMYGCLGFSNSRFYAKPLAELITLQGREILQSTVDLVQNN 1057
              +K QQL+I Q+A+KLTANSMYGCLGFS+SRF+A  +A LIT  GRE L  T D+ +N 
Sbjct: 985  DQVKLQQLEIRQKAIKLTANSMYGCLGFSSSRFHASAIAALITKTGRETLLRTKDIAENK 1044

Query: 1058 LNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEVNKKYRCLEIDLDGLYKRMLLLKKK 1117
            L   V+YGDTDSIMI +G + + ++  + KK+  EVN  Y+CLEI++DG++K +LLLKKK
Sbjct: 1045 LGFNVVYGDTDSIMINTGTNQLQQSLEMGKKLKVEVNCLYKCLEIEIDGVFKSLLLLKKK 1104

Query: 1118 KYAAVKVQFKDGTPYEVI-ERKGLDIVRRDWSLLAKDLGDFCLTQILSGGSCEDVVESIH 1176
            KYAA++ +       +VI E KGLD+VRRDW  L+K +G++ L+QILSG   EDVV +++
Sbjct: 1105 KYAALRYEGVGSNEVKVIQEMKGLDMVRRDWCPLSKSIGNYVLSQILSGKQREDVVFNLN 1164

Query: 1177 NSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDAKNQPHVLVAQRLKQQGYTSGCSVG 1236
              L  + E+M++ ++ L++++ITK LT+    Y D K QPHV VAQRLK QG +    V 
Sbjct: 1165 EYLSDIGEKMKSNRITLDQFIITKQLTRAISEYSDIKGQPHVAVAQRLKNQGKSEADLVN 1224

Query: 1237 DTIPYVICCEQGGSSGSATGIALRARHPDELKQEQGTWLIDIDYYLSQQIHPVISRLCAS 1296
            + IPYVI  +   ++ S   ++ +A HPDEL   +G   +DID+Y++ QI P I+RL   
Sbjct: 1225 NFIPYVIGAQAFDTAKSNPQLSDKAYHPDELLSSKGKITLDIDWYITTQILPPITRLIEH 1284

Query: 1297 IQGTSPERLADCLGLDTSKFQHKSSEASDDPTSSLLFAGDDEES-EKPTSSGTDESDYNF 1355
            I G + E +A CLG+D  K+++ S + + D        GDD  S + P      E     
Sbjct: 1285 IDGINIEFVAQCLGVDPKKYKYHSEKKNTDE------IGDDGGSIQNPILQTETEKSLKH 1338

Query: 1356 WR----KLCCPKCFEN--------------------GAGRISAAMIANQVKRQAEKFVLM 1391
                  K+ CP C  N                       +I    + N+V    ++ + +
Sbjct: 1339 RSIAELKVKCPSCTHNYDFPGIYQEGKDVSGLICTKCNAKIPEKYVMNRVNLFLKQLLAL 1398

Query: 1392 YYRGLLMCDDETCKHTTRSVSFRLVGDSERGTVCPNYPRCNGHLNRKYTEADLYKQLSYF 1451
            YY+G   C + +CK  TR + +           C N   C G +  +Y+E      L Y 
Sbjct: 1399 YYQGKYECQEPSCKSMTRQLLYH--------NKCVNL-TCKGKMVPEYSEHQTNDTLRYL 1449

Query: 1452 CHVFDTVCYIEKMEAKSRIPIEKEL 1476
              +F+   ++ +      + +E ++
Sbjct: 1450 QGLFNIKKHLHENSKNDSLKVETDI 1474


>UniRef100_Q7Z078 DNA polymerase catalytic subunit alpha [Stylonychia lemnae]
          Length = 1514

 Score =  647 bits (1668), Expect = 0.0
 Identities = 411/1165 (35%), Positives = 620/1165 (52%), Gaps = 132/1165 (11%)

Query: 377  GYSLFVWQGTLYQ-------SCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESR-- 427
            G  LF++ G +YQ       SC + V  MQR +YA+P          +  E++ Q  R  
Sbjct: 377  GADLFIF-GKIYQPEINQYVSCSMKVNGMQREIYALPKMQKGKARGTLTREEENQLVRGV 435

Query: 428  -ISPADFRKKLQDAVSDTKNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKI 486
             +   D RKK                   G++ +   PV RKYAFE   I  GE+  +KI
Sbjct: 436  QLELEDIRKKRFQ----------------GITKWRCKPVTRKYAFEMP-IQHGEHLFLKI 478

Query: 487  NYLFKDTALPVDLKGKSFCALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSW 546
             Y      LP  ++G +F  L G+  S LELF++KRKIKGP W+ + N    +  ++ +W
Sbjct: 479  KYDATFIPLPSTVQGNTFECLFGSNQSMLELFILKRKIKGPCWMTIKNPKKVTDFKK-TW 537

Query: 547  CKFEVIVDSPKDIRASSPSSSKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNM 606
            C+ E+ +D+PK+   +    +K  +  PP+       KT    + N NEI   S +  N 
Sbjct: 538  CRQEIEIDNPKNAEVTLDDLNKTDI--PPLTSLTFAFKTA-RSQNNTNEIAMISCLVHNN 594

Query: 607  VKIDTPMLASEWKRPGMLTHFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERA 666
            V  + P    +++       FT++RKLDG   P  F     D+ ++     +   ++ER 
Sbjct: 595  VNQEGPSQTDKFQT------FTLVRKLDGKPMPFDF-----DQKLRQKKENIQYFTNERQ 643

Query: 667  LLNRLMLQLHKMDSDVLVGHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMP--KL 724
            +++  + ++ ++D D++V HN+ G   D+LL R Q  ++  + WS++GR  +  +P  K 
Sbjct: 644  MIDLFVTRIFQIDPDLIVAHNLCGGIFDLLLARIQILKI--NHWSRIGRFKKGNIPTKKF 701

Query: 725  DRRGKTFGFGADPAIMSCVAGRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPH 784
            D  G  +G G+         G LL DT+L +++L++E +Y LTHL K QL + R++    
Sbjct: 702  DTGGANYG-GSQWIPRQVTCGXLLVDTFLSAKELIRETNYDLTHLTKVQLKKDRQDFDDD 760

Query: 785  EVPKMFQTAKSLMELIEYGETDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQ 844
             +P+ +  ++ + +LIE+ E D++ +  LM +LS++PLT+QLTN++GNLW ++LQ ARA+
Sbjct: 761  LLPQFYLASERIFQLIEHSEKDSYYTFMLMLHLSIIPLTKQLTNIAGNLWFRSLQNARAE 820

Query: 845  RVEYLLLHEFHKKKYIVPDKFSNYAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASE 904
            R E LLLHEF KKK+I+PDK    AK+ +                   + D    ND   
Sbjct: 821  RNEMLLLHEFKKKKFILPDKKPPNAKDLRR----------------GFMGDEYEENDTKG 864

Query: 905  SDHKKNK-KAASYAGGLVLEPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSSDDS 963
               K  K K A YAGGLV+EPK G YD  ILLLDFNSLYPSIIQEYN+CFTTV R    +
Sbjct: 865  GGKKGGKRKKAKYAGGLVIEPKAGFYDNIILLLDFNSLYPSIIQEYNLCFTTVNRRPTKN 924

Query: 964  FPR----------------------LPSSKTT---GVLPELLKKLVKLRREKKTWMKTAS 998
            +                        LP         VLP +L+ LV+ R+  K  MK   
Sbjct: 925  YDGSELKNQFKSADNAEGDEVEDVDLPDKNVNIKDAVLPNVLRDLVQKRKAVKEKMKNEK 984

Query: 999  G-LKRQQLDIEQQALKLTANSMYGCLGFSNSRFYAKPLAELITLQGREILQSTVDLVQNN 1057
              +K QQL+I Q+A+KLTANSMYGCLGFS+SRF+A  +A LIT  GRE L  T D+ +N 
Sbjct: 985  DQVKLQQLEIRQKAIKLTANSMYGCLGFSSSRFHASAIAALITKTGRETLLRTKDIAENX 1044

Query: 1058 LNLEVIYGDTDSIMIYSGLDDIAKATSISKKVIQEVNKKYRCLEIDLDGLYKRMLLLKKK 1117
            L   V+YGDTDSIMI +G + + ++  + KK+  EVN  Y+CLEI++DG++K +LLLKKK
Sbjct: 1045 LGFNVVYGDTDSIMINTGTNQLQQSLEMGKKLKVEVNCLYKCLEIEIDGVFKSLLLLKKK 1104

Query: 1118 KYAAVKVQFKDGTPYEVI-ERKGLDIVRRDWSLLAKDLGDFCLTQILSGGSCEDVVESIH 1176
            KYAA++ +       +VI E KGLD+VRRDW  L+K +G++ L+QILSG   EDVV +++
Sbjct: 1105 KYAALRYEGVGSNEVKVIQEMKGLDMVRRDWCPLSKSIGNYVLSQILSGKQREDVVFNLN 1164

Query: 1177 NSLMKVQEEMRNGQVALEKYVITKTLTKPPEAYPDAKNQPHVLVAQRLKQQGYTSGCSVG 1236
              L  + E+M++ ++ L++++ITK LT+    Y D K QPHV VAQRLK QG +    V 
Sbjct: 1165 EYLSDIGEKMKSNRITLDQFIITKQLTRAISEYSDIKGQPHVAVAQRLKNQGKSEADLVN 1224

Query: 1237 DTIPYVICCEQGGSSGSATGIALRARHPDELKQEQGTWLIDIDYYLSQQIHPVISRLCAS 1296
            + IPYVI  +   ++ S   ++ +A HPDEL   +G   +DID+Y++ QI P I+RL   
Sbjct: 1225 NFIPYVIGAQAFDTAKSNPQLSDKAYHPDELLSSKGKITLDIDWYITTQILPPITRLIEH 1284

Query: 1297 IQGTSPERLADCLGLDTSKFQHKSSEASDDPTSSLLFAGDDEES-EKPTSSGTDESDYNF 1355
            I G + E +A CLG+D  K+++ S + + D        GDD  S + P      E     
Sbjct: 1285 IDGINIEFVAQCLGVDPKKYKYHSEKKNTDE------IGDDGGSIQNPILQTETEKSLKH 1338

Query: 1356 WR----KLCCPKCFEN--------------------GAGRISAAMIANQVKRQAEKFVLM 1391
                  K+ CP C  N                       +I    + N+V    ++ + +
Sbjct: 1339 RSIAELKVKCPSCTHNYDFPGIYQEGKDVSGLICTKCNAKIPEKYVMNRVNLFLKQLLAL 1398

Query: 1392 YYRGLLMCDDETCKHTTRSVSFRLVGDSERGTVCPNYPRCNGHLNRKYTEADLYKQLSYF 1451
            YY+G   C + +CK  TR + +           C N   C G +  +Y+E      L Y 
Sbjct: 1399 YYQGKYECQEPSCKSMTRQLLYH--------NKCVNL-TCKGKMVPEYSEHQTNDTLRYL 1449

Query: 1452 CHVFDTVCYIEKMEAKSRIPIEKEL 1476
              +F+   ++ +      + +E ++
Sbjct: 1450 QGLFNIKKHLHENSKNDSLKVETDI 1474


>UniRef100_Q7Z082 DNA polymerase catalytic subunit alpha [Stylonychia lemnae]
          Length = 1514

 Score =  645 bits (1665), Expect = 0.0
 Identities = 406/1147 (35%), Positives = 611/1147 (52%), Gaps = 124/1147 (10%)

Query: 388  YQSCCVVVKNMQRCVYAIPSHPLHSTNEMIQLEKDVQESR---ISPADFRKKLQDAVSDT 444
            Y SC + V  MQR +YA+P          +  E + Q  R   +   D RKK        
Sbjct: 394  YVSCSMKVNGMQREIYALPKMQKGKARGTLTREDENQLVRGVQLELEDIRKKRFQ----- 448

Query: 445  KNEIAKHLVDLGVSSFSMAPVKRKYAFERTDIPAGENYVVKINYLFKDTALPVDLKGKSF 504
                       G++ +   PV RKYAFE   I  GE+  +KI Y      LP  ++G +F
Sbjct: 449  -----------GITKWRCKPVTRKYAFEMP-IQHGEHLFLKIKYDATFIPLPSTVQGNTF 496

Query: 505  CALLGARNSALELFLIKRKIKGPSWLQVSNFSTCSASQRVSWCKFEVIVDSPKDIRASSP 564
              L G+  S LELF++KRKIKGP W+ + N    +  ++ +WC+ E+ +++PK+   +  
Sbjct: 497  ECLFGSNQSMLELFILKRKIKGPCWMTIKNPKKVTDFKK-TWCRQEIEIENPKNAEVTLD 555

Query: 565  SSSKITLVNPPVVVTAINLKTTINEKQNINEIVSASVVSCNMVKIDTPMLASEWKRPGML 624
              +K  +  PP+       KT    + N NEI   S +  N V  + P    +++     
Sbjct: 556  DLNKTDI--PPLTSLTFAFKTA-RSQNNTNEIAMISCLVHNNVNQEGPSQTDKFQT---- 608

Query: 625  THFTVIRKLDGNIFPMGFNTEVTDRNIKAGSNVLCVESSERALLNRLMLQLHKMDSDVLV 684
              FT++RKLDG   P  F     D+ ++     +   ++ER +++  + ++ ++D D++V
Sbjct: 609  --FTLVRKLDGKPMPFDF-----DQKLRQKKENIQYFTNERQMIDLFVTRIFQIDPDLIV 661

Query: 685  GHNISGFDLDVLLHRSQACRVPSSMWSKLGRLNRSTMP--KLDRRGKTFGFGADPAIMSC 742
             HN+ G   D+LL R Q  ++  + WS++GR  +  +P  K D  G  +G G+       
Sbjct: 662  AHNLCGGIFDLLLARIQILKI--NHWSRIGRFKKGNIPTKKFDTGGANYG-GSQWIPRQV 718

Query: 743  VAGRLLCDTYLCSRDLLKEVSYSLTHLAKTQLNQSRKEVAPHEVPKMFQTAKSLMELIEY 802
              GRLL DT+L +++L++E +Y LTHL K QL + R++     +P+ +  ++ + +LIE+
Sbjct: 719  TCGRLLVDTFLSAKELIRETNYDLTHLTKVQLKKDRQDFDDDLLPQFYLASERIFQLIEH 778

Query: 803  GETDAWLSMELMFYLSVLPLTRQLTNLSGNLWGKTLQGARAQRVEYLLLHEFHKKKYIVP 862
             E D++ +  LM +LS++PLT+QLTN++GNLW ++LQ ARA+R E LLLHEF KKK+I+P
Sbjct: 779  SEKDSYYTFMLMLHLSIIPLTKQLTNIAGNLWFRSLQNARAERNEMLLLHEFKKKKFILP 838

Query: 863  DKFSNYAKETKLTKRRVTHGVDDGNFDDADINDANYHNDASESDHKKNK-KAASYAGGLV 921
            DK    AK+ +                   + D    ND      K  K K A YAGGLV
Sbjct: 839  DKKPPNAKDLRR----------------GFMGDEYEENDTKGGGKKGGKRKKAKYAGGLV 882

Query: 922  LEPKKGLYDKYILLLDFNSLYPSIIQEYNICFTTVERSSDDSFPR--------------- 966
            +EPK G YD  ILLLDFNSLYPSIIQEYN+CFTTV R    ++                 
Sbjct: 883  IEPKAGFYDNIILLLDFNSLYPSIIQEYNLCFTTVNRRPTKNYDGSELKNQFKSADNAEG 942

Query: 967  -------LPSSKTT---GVLPELLKKLVKLRREKKTWMKTASG-LKRQQLDIEQQALKLT 1015
                   LP         VLP +L+ LV+ R+  K  MK     +K QQL+I Q+A+KLT
Sbjct: 943  DEVEDVDLPDKNVNIKDAVLPNVLRDLVQKRKAVKEKMKNEKDQVKLQQLEIRQKAIKLT 1002

Query: 1016 ANSMYGCLGFSNSRFYAKPLAELITLQGREILQSTVDLVQNNLNLEVIYGDTDSIMIYSG 1075
            ANSMYGCLGFS+SRF+A  +A LIT  GRE L  T D+ +N L   V+YGDTDSIMI +G
Sbjct: 1003 ANSMYGCLGFSSSRFHASAIAALITKTGRETLLRTKDIAENKLGFNVVYGDTDSIMINTG 1062

Query: 1076 LDDIAKATSISKKVIQEVNKKYRCLEIDLDGLYKRMLLLKKKKYAAVKVQFKDGTPYEVI 1135
             + + ++  + KK+  EVN  Y+CLEI++DG++K +LLLKKKKYAA++ +        VI
Sbjct: 1063 TNQLQQSLEMGKKLKVEVNCLYKCLEIEIDGVFKSLLLLKKKKYAALRYEGVGSNEVXVI 1122

Query: 1136 -ERKGLDIVRRDWSLLAKDLGDFCLTQILSGGSCEDVVESIHNSLMKVQEEMRNGQVALE 1194
             E KGLD+VRRDW  L+K +G++ L+QILSG   EDVV +++  L  + E+M++ ++ L+
Sbjct: 1123 QEMKGLDMVRRDWCPLSKSIGNYVLSQILSGKQREDVVFNLNEYLSDIGEKMKSNRITLD 1182

Query: 1195 KYVITKTLTKPPEAYPDAKNQPHVLVAQRLKQQGYTSGCSVGDTIPYVICCEQGGSSGSA 1254
            +++ITK LT+    Y D K QPHV VAQRLK QG +    V + IPYVI  +   ++ S 
Sbjct: 1183 QFIITKQLTRAISEYSDIKGQPHVAVAQRLKNQGKSEADLVNNFIPYVIGAQAFDTAKSN 1242

Query: 1255 TGIALRARHPDELKQEQGTWLIDIDYYLSQQIHPVISRLCASIQGTSPERLADCLGLDTS 1314
              ++ +A HPDEL   +G   +DID+Y++ QI P I+RL   I G + E +A CLG+D  
Sbjct: 1243 PQLSDKAYHPDELLSSKGKITLDIDWYITTQILPPITRLIEHIDGINIEFVAQCLGVDPK 1302

Query: 1315 KFQHKSSEASDDPTSSLLFAGDDEES-EKPTSSGTDESDYNFWR----KLCCPKCFEN-- 1367
            K+++ S + + D        GDD  S + P      E           K+ CP C  N  
Sbjct: 1303 KYKYHSEKKNTDE------IGDDGGSIQNPILQTETEKSLKHRSIAELKVKCPSCTHNYD 1356

Query: 1368 ------------------GAGRISAAMIANQVKRQAEKFVLMYYRGLLMCDDETCKHTTR 1409
                                 +I    + N+V    ++ + +YY+G   C + +CK  TR
Sbjct: 1357 FPGIYQEGKDVSGLICTKCNAKIPEKYVMNRVNLFLKQLLALYYQGKYECQEPSCKSMTR 1416

Query: 1410 SVSFRLVGDSERGTVCPNYPRCNGHLNRKYTEADLYKQLSYFCHVFDTVCYIEKMEAKSR 1469
             + +           C N   C G +  +Y+E      L Y   +F+   ++ +      
Sbjct: 1417 QLLYH--------NKCVNL-TCKGKMVPEYSEHQTNDTLRYLQGLFNIKKHLHENSKNDS 1467

Query: 1470 IPIEKEL 1476
            + +E ++
Sbjct: 1468 LKVETDI 1474


  Database: uniref100
    Posted date:  Jan 5, 2005  1:24 AM
  Number of letters in database: 848,049,833
  Number of sequences in database:  2,790,947
  
Lambda     K      H
   0.337    0.147    0.483 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,355,257,461
Number of Sequences: 2790947
Number of extensions: 96588912
Number of successful extensions: 402538
Number of sequences better than 10.0: 894
Number of HSP's better than 10.0 without gapping: 701
Number of HSP's successfully gapped in prelim test: 193
Number of HSP's that attempted gapping in prelim test: 397903
Number of HSP's gapped (non-prelim): 1878
length of query: 1510
length of database: 848,049,833
effective HSP length: 141
effective length of query: 1369
effective length of database: 454,526,306
effective search space: 622246512914
effective search space used: 622246512914
T: 11
A: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 39 (21.7 bits)
S2: 82 (36.2 bits)