Medicago
BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC135320.2 + phase: 0 
         (1662 letters)

Database: uniref100 
           2,790,947 sequences; 848,049,833 total letters

Searching..................................................done


                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

UniRef100_Q9LUI2 Centromere protein [Arabidopsis thaliana]           1185  0.0
UniRef100_O23332 Centromere protein homolog [Arabidopsis thaliana]   1052  0.0
UniRef100_Q9SA62 F10O3.10 protein [Arabidopsis thaliana]              947  0.0
UniRef100_Q7XEH4 Putative centromere protein [Oryza sativa]           480  e-133
UniRef100_Q9ZQX8 Hypothetical protein T10P11.22 [Arabidopsis tha...   441  e-122
UniRef100_Q75J40 Putative kinase interacting protein [Oryza sativa]   431  e-118
UniRef100_UPI000049A29E UPI000049A29E UniRef100 entry                 239  4e-61
UniRef100_UPI0000437332 UPI0000437332 UniRef100 entry                 221  1e-55
UniRef100_UPI0000437336 UPI0000437336 UniRef100 entry                 216  4e-54
UniRef100_UPI0000437331 UPI0000437331 UniRef100 entry                 214  2e-53
UniRef100_UPI0000437335 UPI0000437335 UniRef100 entry                 211  1e-52
UniRef100_UPI0000437334 UPI0000437334 UniRef100 entry                 211  1e-52
UniRef100_UPI000043732F UPI000043732F UniRef100 entry                 204  1e-50
UniRef100_UPI0000437337 UPI0000437337 UniRef100 entry                 197  2e-48
UniRef100_UPI0000437333 UPI0000437333 UniRef100 entry                 186  5e-45
UniRef100_UPI0000432990 UPI0000432990 UniRef100 entry                 183  3e-44
UniRef100_UPI000043298D UPI000043298D UniRef100 entry                 182  8e-44
UniRef100_UPI0000432991 UPI0000432991 UniRef100 entry                 181  2e-43
UniRef100_Q5QMF3 Putative kinase interacting protein 1 [Oryza sa...   179  5e-43
UniRef100_UPI00004983A5 UPI00004983A5 UniRef100 entry                 179  6e-43

>UniRef100_Q9LUI2 Centromere protein [Arabidopsis thaliana]
          Length = 1728

 Score = 1185 bits (3066), Expect = 0.0
 Identities = 724/1755 (41%), Positives = 1061/1755 (60%), Gaps = 120/1755 (6%)

Query: 1    MATLSESESRRLYSWWWDSHNSPKNSKWLLENLTDIDTKVKSMIKLIEEEADSFARRAEM 60
            MAT+  SESRRLYSWWWDSH  PKNSKW+ +NL+D+D+KVK+MIKLIEE+ADSFARRAEM
Sbjct: 1    MATVLHSESRRLYSWWWDSH-IPKNSKWIQQNLSDMDSKVKAMIKLIEEDADSFARRAEM 59

Query: 61   YYKKRPELMKLVEEFYRAYRALAERYDHAMGELRHAHKTMPEAFPNSAYYILNDDSPCGS 120
            YYKKRPELMKLVEEFYRAYRALAERYDHA  EL HAHKTM EAFPN   + + +DS   S
Sbjct: 60   YYKKRPELMKLVEEFYRAYRALAERYDHATVELCHAHKTMAEAFPNQVPFDMIEDSASSS 119

Query: 121  LGP---------------DAESHTSARPTHRSKKNERSSEESNGEVQTLREALAKMQSDK 165
                              D++S TS R   +  +   +SE    EV++L+  L ++ ++K
Sbjct: 120  CSEPRTPEKMPPGIQPFYDSDSATSKRGLSQLTEYLGNSET---EVESLKRTLVELGAEK 176

Query: 166  DALFLQYQESLENLSKMETDLNKAQNNARGLDDRASEAEIQVEILKESLMQLKADKDAGE 225
            +AL LQYQ SL   S++E DL  AQ +  GLD+RAS+AEI+ +IL E+L +L+A++DA  
Sbjct: 177  EALNLQYQLSLNKFSRLEKDLEVAQKDVSGLDERASKAEIETKILAEALAKLEAERDAAL 236

Query: 226  VLYNQCLETIARLESMLSQ-------------KDNIEAKNLKQELTRVVVQKDTVLLQYK 272
            + YN+ ++ I  LE   S              K   E +NLKQ  +R+  +K+  L +Y 
Sbjct: 237  LRYNESMQKITELEESFSHAQEDVKGLTNRATKAETEVENLKQAHSRLHSEKEAGLAEYN 296

Query: 273  QCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEERDSLSVLYHHCLE 332
            +CLE I  LE K+  AEEN++  ++Q  + E E++ LR  L ++NE +D L + Y  CLE
Sbjct: 297  RCLEMISNLEKKVRDAEENAQNFSNQSAKAEDEIKALRHELVKVNEVKDGLRLRYQQCLE 356

Query: 333  KISKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQLEAENLVQRIAS 392
             ISK+E E+ H Q+NA++L +++   A KL+  E    +LE SN+ L+LEA+ L  ++A+
Sbjct: 357  TISKLEREVSHAQDNAKRLSSEVLAGAAKLKTVEDQCTLLESSNETLKLEADGLTHKLAA 416

Query: 393  KDHELLEKHTEIERLQTLMHGEHSNFIQIESALQALQKLYSQSQKEQRNLALELKYGLLL 452
            KD E+ +K  E+E+ Q+L+  EHS +++IE +L+ LQ LYSQSQ+EQ+ +  EL+  + +
Sbjct: 417  KDQEIFQKQNELEKFQSLIEDEHSRYLEIEVSLKTLQSLYSQSQEEQKVITSELQSRIGM 476

Query: 453  LKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEISKLKEIKEKLEREFHTS 512
            L+DLE      + ++  + EEN+ L ELN SS   L+ Q+ EIS LKEIKEKLE E    
Sbjct: 477  LRDLETRNLKLEGDISSVKEENQNLSELNDSSMIFLETQKCEISSLKEIKEKLEEEVARH 536

Query: 513  TEESNVLQRETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETC 572
              +S+  Q E  ++KD+I  LN+RYQA++EQ+   GL+P S A SVR LQ+EN  L E C
Sbjct: 537  INQSSAFQEEIRRLKDEIDSLNKRYQAIMEQVNLAGLDPKSLACSVRKLQDENSKLTELC 596

Query: 573  KKEHSEKEALREKSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKS 632
              +  +K+AL EK ++++ +L +N C+E  LL  N +LDG R   K++Q+ C+ L+ EK 
Sbjct: 597  NHQSDDKDALTEKLRELDNILRKNVCLEKLLLESNTKLDGSREKTKDLQERCESLRGEKY 656

Query: 633  ILADEKSTLLSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLND 692
                E++ LLSQLQI+TE+MQK+LE N++LE SLS A IE + ++ KS   E+  +LL +
Sbjct: 657  EFIAERANLLSQLQIMTENMQKLLEKNSLLETSLSGANIELQCVKEKSKCFEEFFQLLKN 716

Query: 693  EKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASILV 752
            +K  L  ER  LISQL  V+EKL  LEKK T LE KYAD++++K+    QVEEL  S+  
Sbjct: 717  DKAELIKERESLISQLNAVKEKLGVLEKKFTELEGKYADLQREKQFKNLQVEELRVSLAT 776

Query: 753  QKENHSNHKHSSEARLANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQNCIEE 812
            +K+  ++++ S++ RLA+L+N V  L+EE R  K EFE+ELDR VNAQ+E+FILQ  IE+
Sbjct: 777  EKQERASYERSTDTRLADLQNNVSFLREECRSRKKEFEEELDRAVNAQVEIFILQKFIED 836

Query: 813  LELKNFVLLTECEKLVEASKFSDKVISELESENLMQLIEEEFLLHRIRKFKMDIHKVCGV 872
            LE KNF LL EC+K  EAS FS+K+I+ELESENL Q +E EFL+H I  F+  I +V   
Sbjct: 837  LEQKNFSLLIECQKYAEASSFSEKLIAELESENLEQQMEAEFLVHEIDNFRGAICQVFKA 896

Query: 873  LQIDSD-GGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSVLLGSLQQHQ 931
            LQ+++D    D +I KE IP+SR+L +I  L+ SL  ++ E Q+L++ENSVLL  L Q Q
Sbjct: 897  LQVEADCKTADQKIAKERIPVSRVLGEINELKCSLSSAEYETQRLVIENSVLLSLLGQFQ 956

Query: 932  SEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKENRSKSTLA 991
            S+G KL+ EK+ VE++ E +     +L+KD++ELLE NRQL+ E+++  ++E   K+ L 
Sbjct: 957  SDGMKLESEKRDVEKDLETIVHHYGMLKKDRLELLEMNRQLKSELIDREQRELELKAELQ 1016

Query: 992  ALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVLALSN 1051
                +   L ++     ++    L +  SL    S+LK      E+EN  +  + +AL+N
Sbjct: 1017 TEHLKFENLHESYMALHQDYSDALGKNKSLHLKFSELKGEICILEEENGAILEEAIALNN 1076

Query: 1052 LNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIER 1111
            +++VY+   +E   +  A  ++L +L ++N+ L Q+   L +  + KE ++  LN  +E+
Sbjct: 1077 VSVVYQSLGSEKAEQAEAFAKNLNSLQNINSGLKQKVETLEEILKGKEVDSQELNSKLEK 1136

Query: 1112 MDK----------------------------ELLEMDKRLKAAETSNAEFSRHIEELKME 1143
            + +                            ELLE ++ LKA   +NAE    +EEL+ +
Sbjct: 1137 LQESLEEANELNDLLEHQILVKEETLRQKAIELLEAEEMLKATHNANAELCEAVEELRKD 1196

Query: 1144 QEESTKIKENLDRQILEQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHRVREEAL 1203
             +ES K+K NL+++  E  +      +EI+ L+   E L+ E+K L  E+++HRVREE L
Sbjct: 1197 CKESRKLKGNLEKRNSELCDLAGRQDEEIKILSNLKENLESEVKLLHKEIQEHRVREEFL 1256

Query: 1204 NLELLNKENEFKLWENEAAAFYHDLQMSSICLALLESKVSELTGVCKILDDESSAKSLEN 1263
            + EL  K NEF LW+ EA +FY DLQ+S++   LLE+KV ELTGVC+ L DE+  K+ E 
Sbjct: 1257 SSELQEKSNEFGLWDAEATSFYFDLQISAVREVLLENKVQELTGVCENLKDEAVTKTTEI 1316

Query: 1264 EHMREIISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLEHISLLWTKRNSVVG---NGAQ 1320
              ++E +  LE E+  LK QLSAY P+V+SL ED  SLE  +L   K     G    G Q
Sbjct: 1317 NQIKETVGFLEFEVSELKTQLSAYDPVVASLAEDVRSLEQNALSLMKLPVPAGRRREGVQ 1376

Query: 1321 KDVVIETCLRKH--SHQSAR-ENEIVLIPDGVSDLLTLQTRIRAVEKIMMEELKRRVKQK 1377
             D   E  + +    H S   +N IVL+ D       ++TRI+ +++ + EE KRR K  
Sbjct: 1377 NDEHQEAAVSQEPVGHCSTNLDNGIVLLQD-------MKTRIKTIKQAVAEEKKRRGK-- 1427

Query: 1378 SLTTESTPYSSLEIATYPKVENRKKEIELVEENVFDRNSWRKKPKIRLLMKDIPLDRNVD 1437
             L   S+ + S +   + ++E    E +   E    R+    + K   LMKDIPLD+  D
Sbjct: 1428 -LRRRSSSHRSKDRKLFEEIE---LEDQFSGEIRQPRSPAMTESKNGSLMKDIPLDQVAD 1483

Query: 1438 DQNSKYLKREHRRTNDHVLELCENNEHEPLSAPTVDHAMICHRSDDS-------GRYLNY 1490
              +    +R  R ++D +LEL E    EP S+      +I +++           R  N 
Sbjct: 1484 TTSYGRSRRTSRGSSDQMLELWE-EAAEPESSIKF---LINNKNSKKPLIPRLHRRSRNP 1539

Query: 1491 SSELDIEKELG-VDKLELSKSVKEKTEDDKRRILERLSSDGQKLAILKMALQDLKKKTET 1549
            S E   EK +G VDKLELS+S      +D  +ILERL SD ++LA L+++L+DLK K E 
Sbjct: 1540 SVESQSEKMVGVVDKLELSRST-----EDNAKILERLLSDSRRLASLRISLRDLKSKLEI 1594

Query: 1550 KKKSKQGNDIEYETVKRHIEEVEEAVMQQVSINDQMAKNVEEGASSLD------REIPRR 1603
             +K  +  + ++  V++ ++E+EEA+ Q  + N+ ++  +EE     D       E  R 
Sbjct: 1595 NEKPGKFTNPDFARVRKQMKEMEEAIFQLANTNEILSNEIEETGDVRDIYRKVVMEKSRI 1654

Query: 1604 GSEQIGKLQFEVQNIQYILLKLAEENNNKVKNR---ISRKTGILLR-------------R 1647
            GSE+I ++Q E+QNI+  +LKL EE   K K R      +T ILLR             +
Sbjct: 1655 GSEKIEQMQQEMQNIERTVLKL-EEGATKSKGRRKFSESRTVILLRDIIHKGGKRTARKK 1713

Query: 1648 KLRVCGCSGPSTNED 1662
            K R CGC   S NE+
Sbjct: 1714 KNRFCGCMRSSGNEE 1728


>UniRef100_O23332 Centromere protein homolog [Arabidopsis thaliana]
          Length = 1676

 Score = 1052 bits (2720), Expect = 0.0
 Identities = 651/1703 (38%), Positives = 1005/1703 (58%), Gaps = 103/1703 (6%)

Query: 36   IDTKVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHAMGELRH 95
            +D+KVK+MIKLIE +ADSFARRA+MY+KKRPELMKLVEE YRAYRALAERYDH   ELR 
Sbjct: 1    MDSKVKTMIKLIEADADSFARRADMYFKKRPELMKLVEELYRAYRALAERYDHTTVELRR 60

Query: 96   AHKTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKNERSSE---------- 145
            AHK M EAFPN   + + +DS   S  P  E+ T A     +K     S+          
Sbjct: 61   AHKVMVEAFPNQMSFDMIEDSASSSSEPRTEADTEALQKDGTKSKRSFSQMNKLDGTSDS 120

Query: 146  -ESNGEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDDRASEAE 204
             E++ EV+TL+  L ++Q++K+AL LQYQ  L  +S+ E +LN AQ + +G D+RA +A+
Sbjct: 121  HEADSEVETLKRTLLELQTEKEALNLQYQLILSKVSRFEKELNDAQKDVKGFDERACKAD 180

Query: 205  IQVEILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNI-------------EAK 251
            I+++ILKESL +L+ ++D G + Y+Q +E IA LE+ +S                  EA 
Sbjct: 181  IEIKILKESLAKLEVERDTGLLQYSQAIERIADLEASISHGQEYAKGLTNRVSEAEREAM 240

Query: 252  NLKQELTRVVVQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRK 311
            +LK+EL+R+  +K+  LL+Y + LE I  LE  I  AEE+ R+  DQ E+ E E++ L++
Sbjct: 241  SLKKELSRLQSEKEAGLLRYNKSLELISSLEKTIRDAEESVRVFRDQSEQAETEIKALKQ 300

Query: 312  NLAEMNEERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGM 371
             L ++NE  + L+V Y  CLE ISK+E E+ H Q+NA++L +++   A K++  E+   +
Sbjct: 301  ELLKLNEVNEDLNVRYQQCLETISKLEREVSHAQDNAKRLSSEVLAGAAKIKTVEEQCAL 360

Query: 372  LEKSNQNLQLEAENLVQRIASKDHELLEKHTEIERLQTLMHGEHSNFIQIESALQALQKL 431
            LE  NQ +++EAENL  ++++KD EL +K  EIE+LQ +M  E   F ++ ++L+ L+ L
Sbjct: 361  LESFNQTMKVEAENLAHKMSAKDQELSQKQNEIEKLQAVMQEEQLRFSELGASLRNLESL 420

Query: 432  YSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQ 491
            +SQSQ+EQ+ L  EL   + +L++LE+     + ++    EEN+ L E+N +S  SL+ Q
Sbjct: 421  HSQSQEEQKVLTSELHSRIQMLRELEMRNSKLEGDISS-KEENRNLSEINDTSI-SLEIQ 478

Query: 492  QMEISKLKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQSLGLNP 551
            + EIS LK++KEKLE E      +S+ LQ E H +K +I  +N RYQ +++Q+   G +P
Sbjct: 479  KNEISCLKKMKEKLEEEVAKQMNQSSALQVEIHCVKGNIDSMNRRYQKLIDQVSLTGFDP 538

Query: 552  NSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDMNEVLMENACMEFSLLGLNDELD 611
             S + SV+ LQ+EN  L E C  +  E  A+  K  +M+ +L  NA +E  LL  N +LD
Sbjct: 539  ESLSYSVKKLQDENSKLVELCTNQRDENNAVTGKLCEMDSILKRNADLEKLLLESNTKLD 598

Query: 612  GLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESMQKILENNTVLEKSLSDAKI 671
            G R   K++ + C+ L+ EKS LA E++ L+SQLQI+T +MQ +LE N+VLEKSLS A I
Sbjct: 599  GSREKAKDLIERCESLRGEKSELAAERANLVSQLQIMTANMQTLLEKNSVLEKSLSCANI 658

Query: 672  EFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEEKYAD 731
            E E LR KS   +D  + L ++K+ L  ER  L+SQL  VEEKL  LEKK T LE +Y D
Sbjct: 659  ELESLRDKSKCFDDFFQFLKNDKSELMKERESLVSQLCKVEEKLGVLEKKYTELEVRYTD 718

Query: 732  VEKDKESAVNQVEELFASILVQKENHSNHKHSSEARLANLENIVRVLQEEQRLGKVEFEQ 791
            +++D +   +QVEEL  S+  +K+  +N+K S+E+RLA+L+  V  L+EE R  K E+E 
Sbjct: 719  LQRDNKLKSHQVEELQVSLAAEKQESANYKRSTESRLADLQKNVSFLREECRSRKREYED 778

Query: 792  ELDRVVNAQIEMFILQNCIEELELKNFVLLTECEKLVEASKFSDKVISELESENLMQLIE 851
            ELDRVVN Q+E+FILQ  IE+LE KNF LL EC+K VEAS+FS+K+I+ELESENL Q +E
Sbjct: 779  ELDRVVNKQVEIFILQKLIEDLEQKNFSLLIECQKHVEASEFSEKLIAELESENLEQQME 838

Query: 852  EEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQE 911
             E  L  I   +  I++V   LQ+++D   + +I K++I +SR L +I+SL+ SL  ++ 
Sbjct: 839  AEIFLDEIDSLRGAIYQVIKALQVEADCKTEQKITKDQISVSRALGEIDSLKGSLSSAEY 898

Query: 912  ENQQLLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQ 971
            E  +L+VENSVLL  L Q QS+G  L+ EK  +E++ +    Q  +L+KDK +L E NR 
Sbjct: 899  EMHRLVVENSVLLSLLGQFQSDGLVLESEKNILEKDLKTKIHQCGMLEKDKQDLQEANRL 958

Query: 972  LRIEVVNGVEKENRSKSTLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDA 1031
            L+ +++   ++E + ++ L     +   L  +  V Q++    L++  +L    S+ KD 
Sbjct: 959  LKSKLIKREQQEQKLRAELKFENLKFESLHDSYMVLQQDYSYTLNDNKTLLLKFSEFKDG 1018

Query: 1032 KSSAEDENSVMFHDVLALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVL 1091
                E+EN  +  + +ALSN  +VY  F +E   E     E + +L  ++  L ++   L
Sbjct: 1019 MHVVEEENDAILQEAVALSNTCVVYRSFGSEMAEEVEDFVETVSSLREISTGLKRKVETL 1078

Query: 1092 RKNFEVKEAENVYLN----------------------------ESIERMDKELLEMDKRL 1123
             K  E KE E+  LN                            E +E  + E+LE +  L
Sbjct: 1079 EKKLEGKEKESQGLNKMLENLQEGLEEDNFLTGLLEHQVSNVDEILEHREMEILEAEHML 1138

Query: 1124 KAAETSNAEFSRHIEELKMEQEESTKIKENLDRQILEQSENCMNHKKEIEHLNEANETLQ 1183
            KA    N E  + +EEL+ + E+S +++ NL+ QI E S+     ++EI  LN  NE L+
Sbjct: 1139 KATNNENEELHKEVEELRKDYEDSRRMRANLEWQISELSDVAGRQEEEIRKLNALNENLE 1198

Query: 1184 FEMKTLLHEVEQHRVREEALNLELLNKENEFKLWENEAAAFYHDLQMSSICLALLESKVS 1243
             E++ L  E+++ +VREE L+LEL  K NE  LW++ A +FY DLQ+S+I   +LE+KV+
Sbjct: 1199 SEVQFLNKEIQRQQVREEYLSLELQEKSNEIGLWDSAATSFYFDLQVSAIRELILENKVN 1258

Query: 1244 ELTGVCKILDDESSAKSLENEHMREIISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLEH 1303
            EL+GVC+ L+DE   K+ + + M+E +  LES++  LK QLSAY P+++SL  D  +LE 
Sbjct: 1259 ELSGVCENLNDEVVTKTTKIKQMKETVGFLESQVTELKSQLSAYDPVIASLAGDVKALEK 1318

Query: 1304 ISLLWTKRNSVVGNGAQKDVVIETCLRKHSHQSARENEIVLIP-DGVSDLLTLQTRIRAV 1362
             +   TK  +             T  ++    +  E+     P +G+  L  +   I+ +
Sbjct: 1319 STHALTKFPA-------------TAYQQRVGNNLEESGSTTSPCNGIVILKEINPSIKTI 1365

Query: 1363 EKIMMEELKRRVKQKSLTTESTPYSSLEIATYPKVENRKKEIELVEENVFDR-NSWRKKP 1421
            E+  ++E  R      L+ + T  +S +     K+EN + + ++  E+   R      + 
Sbjct: 1366 EQAFVKEKGR------LSRQITRSTSQKRRDRRKIENIQPDDQVTGESRQPRLRPEMTEV 1419

Query: 1422 KIRLLMKDIPLDRNVDDQNSKYLKREHRRTNDHVLELCENNEHEPLSAPTVDHAMICHRS 1481
            K  LLMKD P D+  D       +     +ND + E  + +     S   + ++    RS
Sbjct: 1420 KNELLMKDNPRDQVTDSLTYGRSQGTSHGSND-MFEFWDESAESETSVNFLINSNKPQRS 1478

Query: 1482 DDSG-RYLNYSSELDIEKELG-VDKLELSKSVKEKTEDDKRRILERLSSDGQKLAILKMA 1539
             +S  R+ + +  ++ +K +G VDKLELS+++     +DK +ILERL SD ++L+ L+++
Sbjct: 1479 LNSNLRHQSRNPSIESDKAVGVVDKLELSRNI-----EDKAKILERLLSDSRRLSSLRIS 1533

Query: 1540 LQDLKKKTETKKKSKQGNDIEYETVKRHIEEVEEAVMQQVSINDQMAKNVEEGASSLD-- 1597
            L DLK+K E  +K ++ ++ +   VKR ++E+EEAV Q  + N+ ++K +EE   + D  
Sbjct: 1534 LTDLKRKLEMNEKQRRFSNADLVIVKRQLKEMEEAVSQLENTNEILSKEIEETGDARDIY 1593

Query: 1598 ----REIPRRGSEQIGKLQFEVQNIQYILLKLAEENNNKVKNRISR-KTGILLR------ 1646
                 E  R GSE+I +LQ ++QNI+  +LKL +   +K +   S  +T ILLR      
Sbjct: 1594 RKVVVEKSRSGSEKIEQLQNKMQNIEQTVLKLEDGTKSKGRKMFSETRTVILLRDIIHKG 1653

Query: 1647 -------RKLRVCGCSGPSTNED 1662
                   +K R CGC   ST E+
Sbjct: 1654 GKRSARKKKNRFCGCIRSSTKEE 1676


>UniRef100_Q9SA62 F10O3.10 protein [Arabidopsis thaliana]
          Length = 1744

 Score =  947 bits (2449), Expect = 0.0
 Identities = 612/1804 (33%), Positives = 992/1804 (54%), Gaps = 211/1804 (11%)

Query: 1    MATLSESESRRLYSWWWDSHNSPKNSKWLLENLTDIDTKVKSMIKLIEEEADSFARRAEM 60
            M  +    S+R YSWWWDSH SPKNSKWL ENLTD+D+KVK MIK+IEE+ADSFARRAEM
Sbjct: 1    MTAVVNGNSKR-YSWWWDSHISPKNSKWLQENLTDMDSKVKQMIKVIEEDADSFARRAEM 59

Query: 61   YYKKRPELMKLVEEFYRAYRALAERYDHAMGELRHAHKTM-------------------- 100
            YYKKRPELMKLVEEFYRAYRALAERYDHA G +RHA +TM                    
Sbjct: 60   YYKKRPELMKLVEEFYRAYRALAERYDHATGVIRHAQQTMAEAFPNQDPMMFGEESPLGS 119

Query: 101  ---------PEAFPNSAYYILNDDSPCGSLG------------------PDAESHTSARP 133
                     P+++P     +  DD   G+ G                  P + S      
Sbjct: 120  STDGFDPQTPDSYPPIRAPVYPDDLRKGAFGISSSHLSTVKRNIAFMEDPQSVSSGKGFK 179

Query: 134  THRSKK-------------------NERSSEESNGEVQTLREALAKMQSDKDALFLQYQE 174
            T +++K                   +ER+S+ +  E+  L++AL+K+Q++K+A   Q+ +
Sbjct: 180  TAKARKGLNFNNVDGKEINAKVLSESERASK-AEAEIVALKDALSKVQAEKEASLAQFDQ 238

Query: 175  SLENLSKMETDLNKAQNNARGLDDRASEAEIQVEILKESLMQLKADKDAGEVLYNQCLET 234
            +LE LS +E+++++AQ ++R L +RA+ AE +VE L+ESL +++ +K++  + Y QCL+ 
Sbjct: 239  NLEKLSNLESEVSRAQEDSRVLIERATRAEAEVETLRESLSKVEVEKESSLLQYQQCLQN 298

Query: 235  IARLESMLS--QKD-----------NIEAKNLKQELTRVVVQKDTVLLQYKQCLEKIPML 281
            IA LE  +S  QK+             E   LKQ L      K+  L+QY+QCL+ I  L
Sbjct: 299  IADLEDRISLAQKEAGEVDERANRAEAETLALKQSLVSSETDKEAALVQYQQCLKTISNL 358

Query: 282  ENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEERDSLSVLYHHCLEKISKMENEI 341
            E ++  AEE+SR+ N + E  E EVE+L++ ++++ EE ++  + Y  CL+ I+ ++ ++
Sbjct: 359  EERLHKAEEDSRLTNQRAENAEGEVESLKQKVSKLIEENEAYELQYQQCLDTIADLKLKL 418

Query: 342  LHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQLEAENLVQRIASKDHELLEKH 401
             H QE  ++L  +IE    KL+ +E+   +LE+SNQNL  E + L++++ ++ HEL EK 
Sbjct: 419  FHAQEETQRLSREIEDGVAKLKFAEEKCVVLERSNQNLHSELDGLLEKLGNQSHELTEKQ 478

Query: 402  TEIERLQTLMHGEHSNFIQIESALQALQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQ 461
             E+ RL T +  E+  F++ E+A Q LQ+L+SQSQ+E   LALEL+    +LKD+E    
Sbjct: 479  KELGRLWTCVQEENLRFMEAETAFQTLQQLHSQSQEELSTLALELQNRSQILKDMEARNN 538

Query: 462  DFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEISKLKEIKEKLEREFHTSTEESNVLQR 521
              +EE+Q   +++K+L+ELN SS  S+K  Q E+SKL+E  +KLE E     ++ N LQ+
Sbjct: 539  GLQEEVQEAKDQSKSLNELNLSSAASIKSLQEEVSKLRETIQKLEAEVELRVDQRNALQQ 598

Query: 522  ETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEA 581
            E + +K+++  + +++Q+M+EQ++ +GL+P SF +SV++LQ EN  LKE  ++E  EK A
Sbjct: 599  EIYCLKEELSQIGKKHQSMVEQVELVGLHPESFGSSVKELQEENSKLKEIRERESIEKTA 658

Query: 582  LREKSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTL 641
            L EK + M +++ +N  +E S+  LN EL+ +RG +K +++    L EEKS L  EK  L
Sbjct: 659  LIEKLEMMEKLVQKNLLLENSISDLNAELETIRGKLKTLEEASMSLAEEKSGLHSEKDML 718

Query: 642  LSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNER 701
            +S+LQ  TE+ +K+ E N VLE SL +A +E E L+ K   LE+ C LLND+K  L +ER
Sbjct: 719  ISRLQSATENSKKLSEENMVLENSLFNANVELEELKSKLKSLEESCHLLNDDKTTLTSER 778

Query: 702  SMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHSNHK 761
              L+S ++ + +++ +LEK+   L+ K  ++  ++ES++ ++EEL  S+  +   +++  
Sbjct: 779  ESLLSHIDTMRKRIEDLEKEHAELKVKVLELATERESSLQKIEELGVSLNAKDCEYASFV 838

Query: 762  HSSEARLANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQNCIEELELKNFVLL 821
              SE+R+  +E+ +  LQ+E +    E++ ELDR  +A IE+ +LQ C+++   K+  L+
Sbjct: 839  QFSESRMNGMESTIHHLQDENQCRVREYQVELDRAHDAHIEIIVLQKCLQDWLEKSSSLI 898

Query: 822  TECEKLVEASKFSDKVISELESENLMQLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGG 881
             E + + EASK  +K++SELE EN+ + ++ +  ++ I+  +  I++V   L+I    G 
Sbjct: 899  AENQDIKEASKLLEKLVSELEEENIGKQVQIDSSINCIKILRTGIYQVLMKLEIIPGIGS 958

Query: 882  DNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLEK 941
             +E  +++  +  IL+++E +++ L+  ++ENQ   +EN VL+  L+Q +SE   ++ EK
Sbjct: 959  GDENSRDQRNMHDILNRLEDMQTMLLSIRDENQHSAIENLVLIEFLRQLKSEAVGIETEK 1018

Query: 942  KTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKENRSKSTLAALQAEMIELR 1001
            K +E+E E+  +Q    + +  +L+  N +L  +V  GV +E      +     ++++LR
Sbjct: 1019 KILEEELESQCQQLSFSRDETQKLIFVNGELTTKVNQGVNREKVLMVEIEDFHRQVLQLR 1078

Query: 1002 QTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVLALSNLNLVYEIFFT 1061
                + Q +N K LDEK  L ++   L++ K   ED+ S++  + +  SNL ++ E    
Sbjct: 1079 DDYTILQGDNNKTLDEKAYLTKSTLQLEEEKCKLEDDISLLLSETIYQSNLIILLEDVIL 1138

Query: 1062 ENMVEKRALCEHLGNLSHLNNDLNQEFGVL-------------------RKNFEVKEAE- 1101
            E +     L E L  LS +   L +E   L                   + N E+  A  
Sbjct: 1139 EKLSGAMKLNEDLDRLSIVKCKLEEEVRELGDKLKSADIANFQLQVVLEKSNAELLSARS 1198

Query: 1102 -NVYLNESIERM----DKELLEMDKRLKAAETSNAEFSRHIEELKMEQEESTKIKENLDR 1156
             NV+L   I  +    +KELLE    +   +   +E S+ +E L+   +E+  I+E+ D+
Sbjct: 1199 ANVHLEHEIANVKVQKEKELLEAMLMISIMQNEKSELSKAVEGLECRYKEAKAIEEDRDK 1258

Query: 1157 QILEQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLELLNKENEFKL 1216
            Q+L    +     K+  H NEAN  L+ ++  LL E+E+ +V +E LN EL  + NE +L
Sbjct: 1259 QVLRLRGDYDEQVKKNSHSNEANLKLEADLMNLLMELEEIKVEKENLNQELFTERNEIEL 1318

Query: 1217 WENEAAAFYHDLQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMREIISLLESE 1276
            WE+++A  + +LQ+S++   LLE   +EL   CK L+  S+ K  E E ++  ++ LE  
Sbjct: 1319 WESQSATLFGELQISAVHETLLEGLTNELVEACKNLESRSTLKDREIEQLKGRVNNLEDA 1378

Query: 1277 IGGLKEQLSAYVPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVIETCLRKHSHQS 1336
              G  + +  Y   +  LKE   SLE  ++L    N       Q  V I       S+Q 
Sbjct: 1379 NKGQNDLMCKYAQAIFLLKESIQSLEKHAMLHEFENGPATTN-QSFVGI-------SYQE 1430

Query: 1337 ARENEIVLIPDGVSDLLTLQTRIRAVE-----KIMMEELKRRVKQKSLTTESTPYSSLEI 1391
                 +V   DG  ++  L  RI+A+E     K+ MEELK    ++S     +       
Sbjct: 1431 TA--SLVDNSDGFLEIQELHLRIKAIEEAITKKLAMEELKTSSARRSRRRNGS------- 1481

Query: 1392 ATYPKVENRKKEIELVEENVFDRNSWRKKPKIRLLMKDIPLDRNVDDQNSKYLKREHRR- 1450
                    RK+  E+  E            +  ++ KDI LD+  D  +     R+  + 
Sbjct: 1482 -------LRKQNHEIYSE------------ETEMITKDIVLDQVSDCSSYGISTRDILKI 1522

Query: 1451 TNDHVLELCENNEHEPLSAPTVDHAMICHRSDDSGRYLNYSSELDIEKELGVDKLELSKS 1510
             +DH LE    N                      G+ L+       E+ L VDKLE+S  
Sbjct: 1523 EDDHSLEAKSQN-------------------PPKGKSLS-------EESLVVDKLEISDR 1556

Query: 1511 VKEKTED-DKRRILERLSSDGQKLAILKMALQDLKKKTETKKKSKQGNDIEYETVKRHIE 1569
              +  +D +KR++LERL+SD QKL+ L +A++DLK K ET++K ++G + EYET+K  I 
Sbjct: 1557 FTDPNKDANKRKVLERLNSDLQKLSNLHVAVEDLKIKVETEEKDEKGKENEYETIKGQIN 1616

Query: 1570 EVEEAVMQQVSINDQMAKNVEEG-------ASSLD------------REIPRRGSEQIGK 1610
            E EEA+ + +SIN ++   V+ G        SS+D             E  RRGSE+IG+
Sbjct: 1617 EAEEALEKLLSINRKLVTKVQNGFERSDGSKSSMDLDENESSRRRRISEQARRGSEKIGR 1676

Query: 1611 LQFEVQNIQYILLKLAEENNNKVKNRIS-RKTGILLR----------------RKLRVCG 1653
            LQ E+Q +Q++LLKL  +  ++ K +IS  KT ILLR                ++   CG
Sbjct: 1677 LQLEIQRLQFLLLKLEGDREDRAKAKISDSKTRILLRDYIYSGVRGERRKRIKKRFAFCG 1736

Query: 1654 CSGP 1657
            C  P
Sbjct: 1737 CVQP 1740


>UniRef100_Q7XEH4 Putative centromere protein [Oryza sativa]
          Length = 2033

 Score =  480 bits (1235), Expect = e-133
 Identities = 439/1748 (25%), Positives = 791/1748 (45%), Gaps = 195/1748 (11%)

Query: 31   ENLTDIDTKVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHAM 90
            E L     ++KS     +EE D   +       +  EL +  EE  R  + + +  +  +
Sbjct: 317  EELEQKQKELKSFNLTFQEEQDKRMQAESALLSEGKELAQCQEEVQRLTKEI-QMANEKL 375

Query: 91   GELRHAHKTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKNERSS-----E 145
             EL+     +  A       + N            E + S+    +  ++E +S      
Sbjct: 376  NELKQTKVNLENAVSELKKEVENL----------TEQNRSSELLIQELRDEINSLKDSKN 425

Query: 146  ESNGEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDDR------ 199
            E   E+Q+LR  ++++ ++KDA   Q+Q+S+E +S +E+ L K Q     ++ +      
Sbjct: 426  ELQNEIQSLRSTISQLNTEKDATLFQHQQSVERVSDLESQLLKLQPELEEIEQKVQMLMQ 485

Query: 200  ----------ASEAEIQVEILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDN-- 247
                      ++ A++Q E  + +  Q +AD    + L++Q  E + +L   L +     
Sbjct: 486  DLEQKRQEADSAHAQLQDECNRHT--QTEADLHRFKNLHSQLEEEVIKLTENLDRSTKEL 543

Query: 248  -------IEAKNLKQELTRVVV----QKDTVLLQYKQCLEKIPMLENKIALAEENSRMLN 296
                   ++ +N  +EL   ++    +KD VLLQ +Q L KI  LE +++  +   +   
Sbjct: 544  EELENAKLDLENTSRELKSTILDLNSEKDAVLLQQQQSLAKISELELQLSKTQLELKNSE 603

Query: 297  DQIERTELEV-------ETLRKNLAEMNEERD-------SLSVLYHHCLEKISKMENEIL 342
             +++  ELE+       ++L  +L +  E+R        S+  +Y    E+++++  EI 
Sbjct: 604  QKMQLLELEITQKSESMDSLTLSLKDETEKRVQAETSLMSMESMYSQSQEEVNRLHLEIE 663

Query: 343  HVQENAEQLKN------------KIEKEAEKLEISEK--HRGMLEKSNQNLQLEAENLVQ 388
             +     +L+N              EK+A  L+  +       LE     LQ + E +  
Sbjct: 664  KLNFKLNELENLSSELNSTILLLNAEKDATDLKNQQSLVRISDLESELSKLQAQLEKIEG 723

Query: 389  RIASKDHELLEKHTEIERLQTLMHGEHSNFIQIESALQALQKLYSQSQKEQRNLALELKY 448
            ++   + EL  K  E++ LQ  +  E     + E+AL A+  L S+SQ+E   L LE K 
Sbjct: 724  KVQMLEQELKHKKEEVDSLQISIQDEAHKRSEGEAALLAMTNLNSESQEEVNRLTLETKK 783

Query: 449  GLLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEISKLKEIKEKLERE 508
              + L ++E S  D +  +    ++   L E N S+   +K+   E+  LKE+  KLE E
Sbjct: 784  LKVKLSEVENSNTDLENIVAKHTQDIHVLREKNVSTELMIKELHHELDALKELNVKLESE 843

Query: 509  FHTSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFML 568
                  E   LQR+    K++ Q+L   + ++ E++ +L     +    + DLQ  N  L
Sbjct: 844  MGLHIGEKEALQRDFACQKEEKQNLEGIHHSLAEEMSTLKSRSAANQKLIEDLQIMNLKL 903

Query: 569  KETCKKEHSEKEALREKSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQ 628
            KE C K   EK  L EK +++ ++  E + ME SL   N E+D LR  +K ++     L+
Sbjct: 904  KEVCAKNEVEKALLSEKVQEVEKLSEEFSLMENSLSDANAEMDSLREKIKVLETSEGSLK 963

Query: 629  EEKSILADEKSTLLSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCK 688
            +  S    EK+ L S L+ + +S   I E N+ L+  +SD K E E LR K  D E+ C+
Sbjct: 964  DVISSHVSEKAILTSDLETLGKSYADISEKNSNLDILISDMKAEIENLRTKLTDSEETCQ 1023

Query: 689  LLNDEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFA 748
                  + L +E++ + SQLE V   +  LE K  +LE+K + + ++   A +QV EL  
Sbjct: 1024 AHLANNSALSDEKNNVFSQLESVTVVMKALESKHADLEDKSSSLSREMNLAYDQVRELQD 1083

Query: 749  SILVQKENHSNHKHSSEARLANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQN 808
             + V+ E +     S + ++ + E  +  LQ++        EQE +  ++A I + IL+N
Sbjct: 1084 QLRVKDEEYEAFVKSHQTQVNDFEEQISSLQKKSYYMNELLEQEQENHMSASINVVILEN 1143

Query: 809  CIEELELKNFVLLTECEKLVEASKFSDKVISELESENLMQLIEEEFLLHRIRKFKMDIHK 868
            C+ +L+ KN  L  EC+K  EA+  ++ +IS+++ E      E +FLL    K +  I +
Sbjct: 1144 CLADLKDKNVDLFNECQKFAEANHAAEMLISQMKDEARYHQDERKFLLIHTEKLREGISQ 1203

Query: 869  VCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSVLLGSLQ 928
               +L I  D G  N I +++I +  + D+  ++     +S++ N+ +  E +VL   + 
Sbjct: 1204 HMKILNICKDLGPAN-IAEDKIILQTVSDEASNIMKLKEQSEDANRLMYTELTVLATVML 1262

Query: 929  QHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKENRSKS 988
            Q   E   L L+K+ +E+E E    + + LQ + V++LE N QL+ E+  G E+E   K+
Sbjct: 1263 QVGLELRDLNLQKRALEKELETRAAEFITLQNNNVQMLEWNEQLKQELQQGCEREEVLKA 1322

Query: 989  TLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVLA 1048
             +  LQ ++   R++ Q  Q E   + ++  +LC+    L +  ++ EDEN  +  + + 
Sbjct: 1323 EILVLQEKLSCSRESYQTSQNEIVSLTEKNETLCKEYQSLIENYNALEDENGTLLSECMR 1382

Query: 1049 LSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAEN------ 1102
            L +L+L       E      +L + +  LS   ++L+ E   L +   + E+EN      
Sbjct: 1383 LEHLSLFLRGHNNEVATALGSLTDEMALLSVGKDELDCEVQELSRRGMMLESENNNLKEY 1442

Query: 1103 -VYLNE--------------------------------SIERMDKELLEMDKRLKAAETS 1129
             +YL E                                 + + D ELLE + ++   +  
Sbjct: 1443 FIYLIEILSAQLALSEFDLNINKSICQELASELESCMAQLSQKDDELLEAEDKVHLLQGK 1502

Query: 1130 NAEFSRHIEELKMEQEESTKIKENLDRQILEQSENCMNHKKEIEHLNEANETLQFEMKTL 1189
            N E    +  L++  E +  +KE L+++I   +E       EI  L +ANE LQ E   L
Sbjct: 1503 NRELCGVVGSLQVAIEGAKIVKEELEKKITTLTEEGNTKDGEISLLRQANERLQVEADIL 1562

Query: 1190 LHEVEQHRVREEALNLELLNKENEFKLWENEAAAFYHDLQMSSICLALLESKVSELTGVC 1249
              + +      E L+ E+   E EF +  ++A +       SS+  A+ E K  EL    
Sbjct: 1563 KDKEDSLTSSHELLSKEVEQHEGEFVVLMDDAIS-------SSVNAAVYEEKALELM--- 1612

Query: 1250 KILDDESSAKSLENEHMREIISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLEHISLLWT 1309
                                     +E   LK  LS +V L++SL +  N LE  +L  +
Sbjct: 1613 -------------------------TENTELKANLSTHVALIASLSDHVNELEENTLSLS 1647

Query: 1310 KRNSVVGNGAQKDVVIETCLRKHSHQSARENEIVLIPDGVSDLLTLQTRIRAVEKIM--M 1367
            K  S        +V     +++ +H      E   +P+G  +L  L  R+ A++  +   
Sbjct: 1648 KPYSTESKKEDAEVPF---MQERNHGP----ESHPLPEGTPELQRLIARMGALQVAIRNA 1700

Query: 1368 EELKRRVKQKSLTTESTPYSSLEIATYPKVENRKKEIELVEENVFDRNSWRKKPKIRLLM 1427
            ++L  +   KS  T +  +  ++     +  ++ +  E+  +N    N    K K   +M
Sbjct: 1701 KDLHDQESTKSAATLAAAHRDIQ-ELKARGGSQMEAREIYSDNEKLNNVEGSKGKQVQMM 1759

Query: 1428 KDIPLDR-------NVDDQNSKYLKREHRRTNDHVLEL-------CENNEHEPLSAPTVD 1473
            KDI LD+                    +   +D +L+L       C+N   +  SA    
Sbjct: 1760 KDIELDQISTCPPYGTGAALYPLKNGANAGMDDEMLQLWEAAERSCKNQTSKSSSAEHDI 1819

Query: 1474 HAMICHRSDDSGRYLNYSSELDIEKELGVDKLELSKSVKEKTEDDKRRILERLSSDGQKL 1533
             A+   +S+        SSEL   ++LG++KLE+S S  E  E     +LE+LSSD Q+L
Sbjct: 1820 EAVEEVKSEYP------SSELARGRDLGINKLEVSTSSVEPHEQWSNNVLEKLSSDAQRL 1873

Query: 1534 AILKMALQDLKKKTETKKKSKQGNDIEYETVKRHIEEVEEAVMQQVSINDQMAKNVEEGA 1593
              +++++++LK+K  +    K   + EY TV   + + E  V++Q++ N+++ K VE   
Sbjct: 1874 QSIQVSIKELKRKMGSPSNGKSPMNSEYNTVSTQLLDTEGCVLEQINYNNKLTKRVENYP 1933

Query: 1594 SSLD------------REIP---RRGSEQIGKLQFEVQNIQYILLKLAEENNNKVKNRIS 1638
            +  D            R+I    ++GSE +G+L+ E+Q IQY+LLKL EE+  +      
Sbjct: 1934 ALSDSMNAEQEGYPSRRKISGQVQKGSENVGRLELELQKIQYVLLKLEEEHEYRRLKVSD 1993

Query: 1639 RKTGILLR 1646
            ++T +LLR
Sbjct: 1994 KRTRVLLR 2001



 Score =  319 bits (818), Expect = 4e-85
 Identities = 356/1428 (24%), Positives = 648/1428 (44%), Gaps = 184/1428 (12%)

Query: 1    MATLSESESRRLYSWWWDSHNSPKNSKWLLENLTDIDTKVKSMIKLIEEEADSFARRAEM 60
            MA L   ++R+ YSWWW SH SPKNSKWL ENL D+D+KVK+MIKL+ E+ADSFARRAEM
Sbjct: 1    MAALVGHDARQ-YSWWWVSHISPKNSKWLQENLNDMDSKVKAMIKLLNEDADSFARRAEM 59

Query: 61   YYKKRPELMKLVEEFYRAYRALAERYDHAMGELRHAHKTMPEAFPNSAYYILNDDSPCGS 120
            YYKKRPELMKLVEEFYRAYRALAERYD A G LR AHK++ EAFPN     ++D+SP  S
Sbjct: 60   YYKKRPELMKLVEEFYRAYRALAERYDQATGALRQAHKSISEAFPNQ-MPPMSDESPASS 118

Query: 121  LGPDAESHTSARPT----------------------HRSKKNERSSEESN------GEVQ 152
             G + E HT   PT                        SK+N    EE++      G   
Sbjct: 119  -GQEVEPHTPDLPTFTRLPFDLDDLQKDGVGVSPQQFTSKRNGTHPEEASALPNRKGFDV 177

Query: 153  TLREALAKMQSD---KDALFLQYQESLENLSKMETDLNKAQNNARGLDDRASEAEIQVEI 209
             +R+ L+    +    DA+  +     + +S++  + N  +       +RA++AE ++++
Sbjct: 178  KVRKGLSFGSPEVKGSDAISNEMVNLQQEISRLLAESNSMKQQILSESERANKAENEIQV 237

Query: 210  LKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIEAKNLKQELTRVVVQKDTVLL 269
            LK+++++L +DKD   + YNQ  E ++ LES LS+  + + K L  E+   V +  +   
Sbjct: 238  LKDTILKLNSDKDTSLLQYNQSTERLSTLESELSKAQD-DLKKLTDEMATEVQKLSSAEA 296

Query: 270  QYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEERDSLSVLYHH 329
            +  +   ++  L+ K+       +M  +++E+ + E+++      E  ++R         
Sbjct: 297  RNSEIQSELEALDQKV-------KMQQEELEQKQKELKSFNLTFQEEQDKRMQAE----- 344

Query: 330  CLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQLEAENLVQR 389
                +     E+   QE  ++L  +I+   EKL   ++ +  LE +   L+ E ENL ++
Sbjct: 345  --SALLSEGKELAQCQEEVQRLTKEIQMANEKLNELKQTKVNLENAVSELKKEVENLTEQ 402

Query: 390  IASKDHELLEKHTEIERLQTLMHGEHSNFIQIESALQALQKLYSQSQKEQRNLALELKYG 449
              S +  + E   EI  L+   +       ++++ +Q+L+   SQ   E+     + +  
Sbjct: 403  NRSSELLIQELRDEINSLKDSKN-------ELQNEIQSLRSTISQLNTEKDATLFQHQQS 455

Query: 450  LLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEISKLKEIKEKLEREF 509
            +  + DLE      + E++ I ++ + L +         +K+Q   S   +++++  R  
Sbjct: 456  VERVSDLESQLLKLQPELEEIEQKVQMLMQ------DLEQKRQEADSAHAQLQDECNR-- 507

Query: 510  HTSTEESNVLQRETH-QIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFML 568
            HT TE      +  H Q+++++  L E      ++L+ L         +  DL+N +  L
Sbjct: 508  HTQTEADLHRFKNLHSQLEEEVIKLTENLDRSTKELEEL-------ENAKLDLENTSREL 560

Query: 569  KETCKKEHSEKEA-LREKSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVL 627
            K T    +SEK+A L ++ + + ++      +  + L L +    ++    EI Q  + +
Sbjct: 561  KSTILDLNSEKDAVLLQQQQSLAKISELELQLSKTQLELKNSEQKMQLLELEITQKSESM 620

Query: 628  QEEKSILADE-------KSTLLSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKS 680
                  L DE       +++L+S   + ++S +++   +  +EK L+    E E L   S
Sbjct: 621  DSLTLSLKDETEKRVQAETSLMSMESMYSQSQEEVNRLHLEIEK-LNFKLNELENL---S 676

Query: 681  GDLEDCCKLLNDEKN--NLQNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKES 738
             +L     LLN EK+  +L+N++S++  ++  +E +LS L+ ++  +E K   +E++ + 
Sbjct: 677  SELNSTILLLNAEKDATDLKNQQSLV--RISDLESELSKLQAQLEKIEGKVQMLEQELKH 734

Query: 739  AVNQVEELFASILVQKENHSNHKHSSEARLANLENIVRVLQEEQR---LGKVEFEQELDR 795
               +V+ L   I +Q E H   +   EA L  + N+    QEE     L   + + +L  
Sbjct: 735  KKEEVDSL--QISIQDEAHK--RSEGEAALLAMTNLNSESQEEVNRLTLETKKLKVKLSE 790

Query: 796  VVNAQIEMFILQ-------NCIEELELKNFVLLTECEKLVEASKFSDKVISELESENLMQ 848
            V N+  ++  +        + + E  +   +++ E    ++A K   ++  +LESE  + 
Sbjct: 791  VENSNTDLENIVAKHTQDIHVLREKNVSTELMIKELHHELDALK---ELNVKLESEMGLH 847

Query: 849  LIEEEFLLHRIRKFKMDIHKVCGV--------LQIDSDGGGDNEIKKE----EIPISRIL 896
            + E+E L       K +   + G+          + S    + ++ ++     + +  + 
Sbjct: 848  IGEKEALQRDFACQKEEKQNLEGIHHSLAEEMSTLKSRSAANQKLIEDLQIMNLKLKEVC 907

Query: 897  DKIESLESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQNV 956
             K E  ++ L +  +E ++L  E S++  SL    +E + L+ + K +E    ++++   
Sbjct: 908  AKNEVEKALLSEKVQEVEKLSEEFSLMENSLSDANAEMDSLREKIKVLETSEGSLKDVIS 967

Query: 957  ILQKDKVELLEENRQLRIEVVNGVEKENRSKSTLAALQAEMIELR-------QTNQVFQE 1009
                +K  L  +   L     +  EK +     ++ ++AE+  LR       +T Q    
Sbjct: 968  SHVSEKAILTSDLETLGKSYADISEKNSNLDILISDMKAEIENLRTKLTDSEETCQAHLA 1027

Query: 1010 ENGKMLDEKNSLCRNV--------------SDLKDAKSSAEDENSVMFHDVLALSNLNLV 1055
             N  + DEKN++   +              +DL+D  SS   E ++ +  V  L +   V
Sbjct: 1028 NNSALSDEKNNVFSQLESVTVVMKALESKHADLEDKSSSLSREMNLAYDQVRELQDQLRV 1087

Query: 1056 ----YEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENVYLNES--I 1109
                YE F   +  +     E + +L   +  +N+     ++N  +  + NV + E+   
Sbjct: 1088 KDEEYEAFVKSHQTQVNDFEEQISSLQKKSYYMNELLEQEQEN-HMSASINVVILENCLA 1146

Query: 1110 ERMDKELLEMDKRLKAAETSNA----------EFSRHIEELKMEQEESTKIKENL----- 1154
            +  DK +   ++  K AE ++A          E   H +E K     + K++E +     
Sbjct: 1147 DLKDKNVDLFNECQKFAEANHAAEMLISQMKDEARYHQDERKFLLIHTEKLREGISQHMK 1206

Query: 1155 ---------------DRQILEQ-SENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHRV 1198
                           D+ IL+  S+   N  K  E   +AN  +  E+  L   + Q  +
Sbjct: 1207 ILNICKDLGPANIAEDKIILQTVSDEASNIMKLKEQSEDANRLMYTELTVLATVMLQVGL 1266

Query: 1199 REEALNLELLNKENEFKLWENEAAAFYHDLQMSSI-CLALLESKVSELTGVC---KILDD 1254
                LNL+    E E    E  AA F   LQ +++  L   E    EL   C   ++L  
Sbjct: 1267 ELRDLNLQKRALEKEL---ETRAAEFI-TLQNNNVQMLEWNEQLKQELQQGCEREEVLKA 1322

Query: 1255 ESSAKSLENEHMREIISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLE 1302
            E      +    RE     ++EI  L E+         SL E++N+LE
Sbjct: 1323 EILVLQEKLSCSRESYQTSQNEIVSLTEKNETLCKEYQSLIENYNALE 1370


>UniRef100_Q9ZQX8 Hypothetical protein T10P11.22 [Arabidopsis thaliana]
          Length = 1111

 Score =  441 bits (1135), Expect = e-122
 Identities = 322/1106 (29%), Positives = 561/1106 (50%), Gaps = 153/1106 (13%)

Query: 1    MATLSESESRRLYSWWWDSHNSPKNSKWLLENLTDIDTKVKSMIKLIEEEADSFARRAEM 60
            M   ++S S+R+YSWWWDSHN+PKNSKWL +NL D+D+ VK MIK++EE+ADSFARRAEM
Sbjct: 1    MEIAAKSNSKRMYSWWWDSHNTPKNSKWLQDNLADMDSNVKQMIKVLEEDADSFARRAEM 60

Query: 61   YYKKRPELMKLVEEFYRAYRALAERYDHAMGELRHAHKTMPEAFPNSAYYILNDDSPCGS 120
            YY+KRPELMKLVEEFYRAYRALAERY+HA G +  AH+T+ EAFPN    I  D+S  G+
Sbjct: 61   YYRKRPELMKLVEEFYRAYRALAERYNHATGVIHKAHETIAEAFPNQVPLIFGDESHGGA 120

Query: 121  LGPDAESHTSARP-----------------------THRSKKNERSSEE----SNG---- 149
            L  D +  T   P                        H  K+N   SEE    SNG    
Sbjct: 121  LTNDVDPQTPDMPPPFRARGNPDEFQQDALGFSLSHVHDVKRNIDFSEEPLFVSNGKARK 180

Query: 150  --------------------------------EVQTLREALAKMQSDKDALFLQYQESLE 177
                                            EV  L+++L+KMQ++K A    ++++LE
Sbjct: 181  GLNFNDHGDGKGRNGLKDHILSESERASKAEAEVVALKDSLSKMQAEKQASLALFEKNLE 240

Query: 178  NLSKMETDLNKAQNNARGLDDRASEAEIQVEILKESLMQLKADKDAGEVLYNQCLETIAR 237
             LS +E+++++AQ ++RG++DRA+ AE +++ L+E+L +L+++K++  + Y++CL+ IA 
Sbjct: 241  RLSNLESEVSRAQADSRGINDRAASAEAEIQTLRETLYKLESEKESSFLQYHKCLQKIAD 300

Query: 238  LESMLS----------QKDNIEAKNLKQELTRVVVQKDTVLLQYKQCLEKIPMLENKIAL 287
            LE  LS           K   E   LK+ L +    K+T L+QY+QCL  I  LE ++  
Sbjct: 301  LEDGLSVAHKEAGERASKAETETLALKRSLAKAETDKETALIQYRQCLNTISNLEERLRK 360

Query: 288  AEENSRMLNDQIERTELEVETLRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHVQEN 347
            AEE++R++N++ E+  +EVE L++ ++++ +++++  + +  CL  I+ ++ ++ H QE 
Sbjct: 361  AEEDARLINERAEKAGVEVENLKQTVSKLIKDKEASELQFQQCLNIIASLKVKLHHAQEE 420

Query: 348  AEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQLEAENLVQRIASKDHELLEKHTEIERL 407
             + L ++IE    KL+ SE+   +LE+SNQNL  E ++L++++ ++  +L EK TE+ +L
Sbjct: 421  TQSLSHEIEDGVAKLKFSEEKCLLLERSNQNLHSELDSLLEKLGNQSQKLTEKQTELVKL 480

Query: 408  QTLMHGEHSNFIQIESALQALQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEM 467
             + +  EH +F + E+A Q LQ+L+SQSQ+E  NLA+EL+    ++KD+E+   +  EE+
Sbjct: 481  WSCVQAEHLHFQEAETAFQTLQQLHSQSQEELNNLAVELQTVSQIMKDMEMRNNELHEEL 540

Query: 468  QGIVEENKTLHELNFSSTRSLKKQQM---EISKLKEIKEKLEREFHTSTEESNVLQRETH 524
            +    ENK L++LNF+  + ++K  M    IS L    E   R+  T  E    L  E  
Sbjct: 541  EQAKVENKGLNDLNFTMEKLVQKNLMLEKSISYLNSELESFRRKLKTFEEACQSLSEEKS 600

Query: 525  QIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALRE 584
             +  + QH       ++E L+ L L     A    DL+ +   + +  K   +E E L+ 
Sbjct: 601  CLISENQHNVIENTVLIEWLRQLRLEAVGIATEKTDLEGKAKTIGD--KLTDAETENLQL 658

Query: 585  KSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQ 644
            K +++  +  E   +E  +  + D+L       +EI+   + L +E  +  + K   L +
Sbjct: 659  K-RNLLSIRSEKHHLEDEITNVKDQLHEKEKEFEEIKMEKEKLIQE--VFKERKQVELWE 715

Query: 645  LQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDE--KNNLQNERS 702
             Q  T    K +   +V+ ++L +A          + +L + CK L  +    +   E+ 
Sbjct: 716  SQAATFFCDKQI---SVVHETLIEA---------TTRELAEACKNLESKSASRDADIEKL 763

Query: 703  MLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVE--------ELFASILVQK 754
                 + ++ E + +LE  V    E   +V K  +     ++        +  A  +++K
Sbjct: 764  KRSQTIVLLNESIKSLEDYVFTHRESAGEVSKGADLMDEFLKLEGMCLRIKAIAEAIMEK 823

Query: 755  E-----NHSNHKHSSEARLANLENIV----RVLQEEQ----RLGKVEFEQE-------LD 794
            E      ++N     EA L  ++ +     R ++++     R+ K   E E       LD
Sbjct: 824  EKFLMLENTNTYSMLEASLKQIKELKTGGGRSMRKQDGGSGRMRKQSHETEMVMKDIVLD 883

Query: 795  RVVNAQIEMFILQNCIEELELKNFVLLTECEKLVEASKFSDKVISELESENLMQLIEEEF 854
            +  +      + +    EL+   FV L    K V+  K   K +SE   E+L  ++E+  
Sbjct: 884  QTSDGSSYEIVSKKGNSELDHLGFVEL----KPVKTHKTETKALSE---ESL--IVEKVE 934

Query: 855  LLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQ 914
            +         +++K   + ++DSD     +++  +I +  +  K+E++E    K  E   
Sbjct: 935  IFDGFMDPNREVNKRRVLERLDSD---LQKLENLQITVEDLKSKVETVEKEKTKVGEN-- 989

Query: 915  QLLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRI 974
                E   + G L++ +   EKL    + +  + E+ ++            ++  R++  
Sbjct: 990  ----EYKTIKGQLEEGEEAIEKLFTVNRKLTTKAESEKD------------IDRRRRIFE 1033

Query: 975  EVVNGVEKENRSKSTLAALQAEMIEL 1000
                G EK  R +S +  +Q  +++L
Sbjct: 1034 HARRGTEKIGRLQSEIQRIQFLLMKL 1059



 Score =  184 bits (467), Expect = 2e-44
 Identities = 234/985 (23%), Positives = 436/985 (43%), Gaps = 150/985 (15%)

Query: 690  LNDEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFAS 749
            L D  + +Q E+   ++  E   E+LSNLE +V+  +     +     SA  +++ L  +
Sbjct: 217  LKDSLSKMQAEKQASLALFEKNLERLSNLESEVSRAQADSRGINDRAASAEAEIQTLRET 276

Query: 750  ILV---QKENHSNHKHSSEARLANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFIL 806
            +     +KE+     H    ++A+LE+ + V  +E            +R   A+ E   L
Sbjct: 277  LYKLESEKESSFLQYHKCLQKIADLEDGLSVAHKEAG----------ERASKAETETLAL 326

Query: 807  QNCIEELELKNFVLLTECEKLVEASKFSDKVISELESENLMQLIEEEFLLHRIRKFKMDI 866
            +  + + E      L +  + +         IS LE    ++  EE+  L   R  K  +
Sbjct: 327  KRSLAKAETDKETALIQYRQCLNT-------ISNLEER--LRKAEEDARLINERAEKAGV 377

Query: 867  HKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSVLLGS 926
             +V  + Q  S    D E    E+   + L+ I SL+  L  +QEE Q L          
Sbjct: 378  -EVENLKQTVSKLIKDKEAS--ELQFQQCLNIIASLKVKLHHAQEETQSL---------- 424

Query: 927  LQQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEE--NRQLRIEVVNGVEKEN 984
               H+ E    KL  K  E++   +   N  L  +   LLE+  N+  ++      EK+ 
Sbjct: 425  --SHEIEDGVAKL--KFSEEKCLLLERSNQNLHSELDSLLEKLGNQSQKL-----TEKQT 475

Query: 985  RSKSTLAALQAEMIELRQTNQVFQ---EENGKMLDEKNSLCRNVSDLKDAKSSAEDENSV 1041
                  + +QAE +  ++    FQ   + + +  +E N+L   +  +       E  N+ 
Sbjct: 476  ELVKLWSCVQAEHLHFQEAETAFQTLQQLHSQSQEELNNLAVELQTVSQIMKDMEMRNNE 535

Query: 1042 MFHDV--LALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFE--- 1096
            +  ++    + N  L    F  E +V+K  + E   ++S+LN++L + F    K FE   
Sbjct: 536  LHEELEQAKVENKGLNDLNFTMEKLVQKNLMLEK--SISYLNSEL-ESFRRKLKTFEEAC 592

Query: 1097 --VKEAENVYLNESIERMDKE--LLEMDKRLKAAETSNAEFSRHIE-ELKMEQEESTKIK 1151
              + E ++  ++E+   + +   L+E  ++L+      A     +E + K   ++ T   
Sbjct: 593  QSLSEEKSCLISENQHNVIENTVLIEWLRQLRLEAVGIATEKTDLEGKAKTIGDKLT--- 649

Query: 1152 ENLDRQILEQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLELLNKE 1211
             + + + L+   N ++ + E  HL +    ++ ++     E E+ ++ +E L  E+  + 
Sbjct: 650  -DAETENLQLKRNLLSIRSEKHHLEDEITNVKDQLHEKEKEFEEIKMEKEKLIQEVFKER 708

Query: 1212 NEFKLWENEAAAFYHDLQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMREIIS 1271
             + +LWE++AA F+ D Q+S +   L+E+   EL   CK L+ +S+++  + E ++   +
Sbjct: 709  KQVELWESQAATFFCDKQISVVHETLIEATTRELAEACKNLESKSASRDADIEKLKRSQT 768

Query: 1272 LLESEIGGLKEQLSAYVPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVIETCLRK 1331
            ++                    L E   SLE       +    V  GA            
Sbjct: 769  IV-------------------LLNESIKSLEDYVFTHRESAGEVSKGAD----------- 798

Query: 1332 HSHQSARENEIVLIPDGVSDLLTLQTRIRAVEKIMMEELKRRVKQKSLTTEST-PYSSLE 1390
                         + D    L  +  RI+A+ + +ME      K+K L  E+T  YS LE
Sbjct: 799  -------------LMDEFLKLEGMCLRIKAIAEAIME------KEKFLMLENTNTYSMLE 839

Query: 1391 IATYPKVENRKKEIELVEENVFDRNSWRKKP-KIRLLMKDIPLDRNVDDQNSKYLKREHR 1449
             +     E +      + +        RK+  +  ++MKDI LD+  D  + + + ++  
Sbjct: 840  ASLKQIKELKTGGGRSMRKQDGGSGRMRKQSHETEMVMKDIVLDQTSDGSSYEIVSKKGN 899

Query: 1450 RTNDHVLELCENNEHEPLSAPTVDHAMICHRSDDSGRYLNYSSELDIEKELGVDKLELSK 1509
               DH+  +    E +P+           H+++         ++   E+ L V+K+E+  
Sbjct: 900  SELDHLGFV----ELKPVKT---------HKTE---------TKALSEESLIVEKVEIFD 937

Query: 1510 SVKE-KTEDDKRRILERLSSDGQKLAILKMALQDLKKKTET--KKKSKQGNDIEYETVKR 1566
               +   E +KRR+LERL SD QKL  L++ ++DLK K ET  K+K+K G + EY+T+K 
Sbjct: 938  GFMDPNREVNKRRVLERLDSDLQKLENLQITVEDLKSKVETVEKEKTKVGEN-EYKTIKG 996

Query: 1567 HIEEVEEAVMQQVSINDQMAKNVEEGASSLDR-----EIPRRGSEQIGKLQFEVQNIQYI 1621
             +EE EEA+ +  ++N ++     E    +DR     E  RRG+E+IG+LQ E+Q IQ++
Sbjct: 997  QLEEGEEAIEKLFTVNRKLTTKA-ESEKDIDRRRRIFEHARRGTEKIGRLQSEIQRIQFL 1055

Query: 1622 LLKLAEENNNKVKNRISRKTGILLR 1646
            L+KL  E  ++++++IS  T +LLR
Sbjct: 1056 LMKLEGEREHRLRSKIS-DTKVLLR 1079


>UniRef100_Q75J40 Putative kinase interacting protein [Oryza sativa]
          Length = 1500

 Score =  431 bits (1107), Expect = e-118
 Identities = 358/1434 (24%), Positives = 687/1434 (46%), Gaps = 119/1434 (8%)

Query: 286  ALAEENSRM------LNDQIERTELEVETLRKNLAEMNEERDSLSVLYHHCLEKISKMEN 339
            +L+EEN  +      L +Q  + ELEV  L++ LA+ N E++++ +       ++  +++
Sbjct: 129  SLSEENKDLKSRISSLLEQTNKAELEVVCLKEALAQQNTEKEAIVLQCQQSTARLQNLKS 188

Query: 340  EILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQLEAENLVQRIASKDHELLE 399
            EILH QE   +LK +++   +    +++   +LEK+NQ + LE   L   +  K  EL E
Sbjct: 189  EILHTQEKFNRLKEEMQSGFQPFTTADERSVLLEKANQEMNLELNKLKHMLKQKHEELNE 248

Query: 400  KHTEIERLQTLMHGEHSNFIQIESALQALQKLYSQSQKEQRNLALELKYGLLLLKDLELS 459
            K  E+E+L      EH   +Q E A  +L+K    +Q + R LALE +  +   KD E  
Sbjct: 249  KQAELEKLNISTEEEHLKCMQAEMAQLSLEKQLILAQDKMRLLALEKQIEVSKAKDTETE 308

Query: 460  KQDFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEISKLKEIKEKLEREFHTSTEESNVL 519
            K   ++E++ I +E+ +L++   SS+  + + Q EI  +K  + +LE +     +E   L
Sbjct: 309  KVMLEKELEKIQKESTSLNDQIHSSSSMIIRLQDEIITMKNAQRRLEEDVCRHVDEKKTL 368

Query: 520  QRETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEK 579
            Q E   +K+D   L++++ ++ EQ+Q++ LN  S  A V++L++ N  LK   +   S +
Sbjct: 369  QNELCHLKEDRSDLDKKHSSIKEQIQAVDLNVESLQALVQELKDGNVELKGIIRNHESTE 428

Query: 580  EALREKSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKS 639
                E  + +  +  +N+ +E SL  +  EL+ LR    E+++ C+ L  + S    E++
Sbjct: 429  VLHIENLRRLERMSEKNSYLEKSLSAVTTELEVLREKKAELEESCKHLSSKISSHQSERA 488

Query: 640  TLLSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQN 699
             L++Q++ I+++M ++ E N  LE SLSDA  E E LR K  +LE+  + L  + + LQ+
Sbjct: 489  VLVAQIEAISQTMAELFEKNVFLENSLSDANAELESLRGKLKELEESSEALYSQNSALQH 548

Query: 700  ERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHSN 759
            E+S L  Q++ + + L NLE     LE++++D++++K S +++V +L   I  +++ H++
Sbjct: 549  EKSTLACQVDRISDTLQNLEAHYAELEKRHSDLQEEKGSVLDEVIKLQEQIRFERKEHND 608

Query: 760  HKHSSEARLANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQNCIEELELKNFV 819
             +HS +++L  L   + VL +E    + + E+E   +V AQ E+FI + C+E++      
Sbjct: 609  LEHSRKSQLDALHEKINVLSQEGWNREEQLEEEEQNIVKAQTEIFIWKQCLEDI------ 662

Query: 820  LLTECEKLVEASKFSDKVISELESENLMQLIEE--EFLLHRIRKFKMDIHKVCGVLQIDS 877
                      A   SD +      + + Q++EE  E+L    +K    I  V  VL ++ 
Sbjct: 663  ----------ADANSDFLAQLKMKQEVCQVLEEKMEYLSENNQKLTKCIGSVLKVLHLEE 712

Query: 878  DGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKL 937
                 +++K + I +  IL +I  L +++  +Q+  Q  LVE S+++  L+    E   L
Sbjct: 713  KYESLDQMKLDSI-VHLILHEINCLLNTISDAQDVKQNELVEKSLVVTLLEHFGQEVADL 771

Query: 938  KLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKENRSKSTLAALQAEM 997
            + E+ T++QE +   E+ + LQ++K EL+    +   EV     K +  ++    L  ++
Sbjct: 772  RSERNTLKQEQQAKSEELLQLQREKQELVNITDEFWEEVETRNRKVDELRAEAKFLVGQL 831

Query: 998  IELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVLALSNLNLVYE 1057
             EL+ + +  Q E  K++ E + L   + D ++ +   ED+ S++  +V++   L++V+ 
Sbjct: 832  SELQGSRRSLQSEIIKLIQENSMLSDELCDSREKERVFEDDFSILISEVMSKDILSVVFR 891

Query: 1058 IFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIERMDKELL 1117
                E  ++  +L      L    ++L Q+  ++       E E+          +KEL 
Sbjct: 892  SLHEERTLQLVSLHSDFAQLQAAGSELYQDIKMMNMKLGDLEKES-------NECNKELS 944

Query: 1118 EMDKRLKAAETSNAEFSRHIEELKMEQEESTKIKENLDRQILEQSENCMNHKKEIE--HL 1175
                   +  T NA  S +      +         N  R  LE   N    + E++   L
Sbjct: 945  RTISICNSTSTENAIGSGYPVGRDTDH-------LNSGRSQLEYHVNMETGEIEVDMAGL 997

Query: 1176 NEANETLQFEMKTLLHEVEQHRVREEALNLELLNKENEFKLWENEAAAFYHDLQMSSICL 1235
             ++NE LQ E+  +  E+E    +E        N   + K  + +      ++QM+ +  
Sbjct: 998  EKSNEMLQEEVHKMQSEMEVLTSKE--------NSAIDIKSCDEDIKRLLANMQMAIVNA 1049

Query: 1236 ALLESKVSELTGVCKILDDESSAKSLENEHMREIISLLESEIGGLKEQLSAYVPLVSSLK 1295
            AL + KV EL   C+  +  S    ++ E ++E I+   S +  LK++L+A       LK
Sbjct: 1050 ALFKEKVLELIITCESFEISS---MVQKEVLKEEITRRNSYVDELKDKLNAVEIENRRLK 1106

Query: 1296 EDFNSLEHISLLWTKRNSVVGNGAQKDVVIETCLRKHS---HQSARENEIVLIPDGVSDL 1352
             D N     ++L + +N V     Q   +   CL+ +     ++A   +++      S  
Sbjct: 1107 VDLNG--DFTVLGSLQNEVSALEKQTLSLANDCLQSNKLRMEENALSTQVLKTNMRSSG- 1163

Query: 1353 LTLQTRIRAVEKIMMEELKRRVK--QKSLTTESTPYSSLEIATYPKVENRKKEIELVE-E 1409
               Q  +R V+ + +++L   +K  QK +T  +       +     ++  +K+IE+++ +
Sbjct: 1164 --DQNTVRTVKDMELQKLHGTIKALQKVVTDTAVLLDQERLDFNANLQEARKQIEVLKLK 1221

Query: 1410 NVFDRNSWRKKPKIRLLMKDIPLD----------RNVDDQNSKYLKREHRRTNDH-VLEL 1458
             + D +    +     ++KDI LD           ++   N    +   +  + H ++  
Sbjct: 1222 EILDDD--LIEMNYEQMLKDIQLDLIQISSGNKTGSLGQANKTVAQANEKMLDSHGIVGA 1279

Query: 1459 CENNEHEPLSAPTVDHAMICHRSDDSGRYLNYSSELDIEKELGVDKLELSKSV-KEKTED 1517
              ++    L  P  +       S +   Y    SEL + KEL +DK EL +S+  E  ++
Sbjct: 1280 SSSHVRNDLRPPQSE-------SFERDNYKRPPSELMVVKELSIDKQELPRSITTEPHQE 1332

Query: 1518 DKRRILERLSSDGQKLAILKMALQDLKKKTETKKKSKQGNDIEYETVKRHIEEVEEAVMQ 1577
             K +++ERL+SD Q+L  L+ ++Q+LK  TE  +       +E E+V+  I E E  + Q
Sbjct: 1333 WKNKVIERLASDAQRLNALQSSIQELKTNTEASE------GLELESVRYQIREAEGFITQ 1386

Query: 1578 QVSINDQMAKNVEEGAS--SLD--------------REIPRRGSEQIGKLQFEVQNIQYI 1621
             +  N +++K  EE  S   LD               E  R+ +E+IG+L+ E+Q +Q  
Sbjct: 1387 LIDSNGKLSKKAEEFTSEDGLDGDNIDLRSRHQRKIMERARKMAEKIGRLEVEMQKVQEA 1446

Query: 1622 LLKLAEENNNKVKNRISRKTGILL-------------RRKLRVCGCSGPSTNED 1662
            LLK  E+ + +    + R++ + L             +++   CGC   +  +D
Sbjct: 1447 LLKYEEQTSTRTSKTMHRRSKVQLVDFLYGRRRDSRKQQRCSPCGCMKANAIDD 1500


>UniRef100_UPI000049A29E UPI000049A29E UniRef100 entry
          Length = 1813

 Score =  239 bits (611), Expect = 4e-61
 Identities = 357/1693 (21%), Positives = 712/1693 (41%), Gaps = 296/1693 (17%)

Query: 127  SHTSARPTHRSKKNERSSEESNGEVQTLREALAKMQSDKDALFLQYQES----------L 176
            S T+A   +RS   +   EE N  +Q   E L K    +D+L     +S          L
Sbjct: 167  SETTAEEVNRSVNAQ--IEEENKRLQNENEELKKKCDAQDSLLKTKMKSEMEAKKKVEIL 224

Query: 177  EN---------------LSKMETDLNKAQNNARGLDDRASEAEIQVEILKESLMQLKADK 221
            EN               +SK+  +L + +N    +++   + + + E +   L QLK D 
Sbjct: 225  ENEKKDLIDKMANENDGMSKLNEELTQIKNEKESINNELIQTKQEKESINNELTQLKTDN 284

Query: 222  DAGEVLYNQCL----ETIARLESMLSQKDNI--EAKNLKQELTRVVVQKDTVLLQYKQCL 275
            D  E   NQ      E I +  +   + + I  E   LKQE      +++ +  Q K+  
Sbjct: 285  DQKENELNQVRHEKDEVIEKFNTSKEENEKIMNELSQLKQEKEE---KENELKEQVKKME 341

Query: 276  EKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEERDSLSVLYHHCLEKIS 335
            E+   L  +++   +    LN+++ +T+ E E +   L  + EE+           ++I 
Sbjct: 342  EEKSKLITELSNGSDGISKLNEELTQTKQEKEEINNELNSIKEEK-----------KRIE 390

Query: 336  KMENEILHVQENAEQLKNKIEKEAEKL--EISEKHRGMLEKSNQ--NLQLEAENLVQR-- 389
            + +N+I++  +  ++ K KIE+E ++L  EI ++  G  +  N+   +Q   + + ++  
Sbjct: 391  EEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQ 450

Query: 390  --IASKDHELLEKHTEIERLQTLMHGEHSNFIQIESALQALQKLYSQSQKEQRNLALELK 447
              I   + E+ +   E E LQ  ++       + E+    L  + +Q + E   L  E +
Sbjct: 451  EIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEKNELVDVKTQKENELNKLKEEKE 510

Query: 448  YGLLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEISKLKEIKEKLER 507
                    +E S     EE   + EE +++ +   S       +++EI+K+ E K +L+ 
Sbjct: 511  QIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELDSIKADNSTKELEINKINEEKNQLQN 570

Query: 508  EFHTSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNEN-- 565
            ++ T  +E   +Q+E +QIK +     E    + E+ Q +    +  A  + D+ N N  
Sbjct: 571  DYDTVQQEKENIQKELNQIKIEKSQKEEELNKIKEEKQQV---EDEKAKLITDIANGNDG 627

Query: 566  -FMLKETCKKEHSEKEALREK-----------SKDMNEVLMENACMEFSLLGLNDELDGL 613
               L E   K   EKE +  +           S + N+   E    E   + LN+E   L
Sbjct: 628  LTKLNEVIDKLKDEKENISNELNQIKNERDNISNEFNKTKEEIKQKENETIQLNEEKSVL 687

Query: 614  RGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESMQKILENNTVLEKSLSDAKIEF 673
               + +I++  Q +++EK+++  EK   +++L           E+ TV+E  L+  K E 
Sbjct: 688  LNELNQIKEEKQKIEDEKAVIQQEKENEITKLN----------EDKTVIENELNQIKTEK 737

Query: 674  EGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVE 733
            +       ++E+      DEK  +++E+S LI++L    + +S L +++T  +++  +V 
Sbjct: 738  Q-------EIENELNQTKDEKQKIEDEKSKLITELSNGNDGISKLNEELTQTKQEKENVL 790

Query: 734  KDKESAVNQVEELFASIL---VQKENHSNHKHSS-EARLANLENIVRVLQEEQRLGKVEF 789
             +    +NQ++  FAS      QKEN    +++  +  L    N V  L+EE+     E 
Sbjct: 791  NE----LNQIKNEFASFKEQNTQKENELKDENNKVQQELEQKNNEVSKLEEEKGNISNEL 846

Query: 790  EQELDRVVNAQIEMFILQNCIEELELKNFVLLTECEKLVEASKFSDKVISELE--SENLM 847
                  +   + E+  +    EE E +    L E  K +E  K   K+I+EL   S+ + 
Sbjct: 847  SNTKQELEQKKQEIITITQEKEEKENE----LKEQVKKIEEEK--SKLITELSNGSDGIS 900

Query: 848  QLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLV 907
            +L EE   L + ++ K +I K                +++E+  + RI  +++ ++ +  
Sbjct: 901  KLNEE---LTQTKQEKEEIQKA---------------LEEEKEKLERIETELKEIKEAKQ 942

Query: 908  KSQEENQQLLVENSVLLGSLQQHQSEGEKL---KLEKKTVEQEFENMREQNVILQKDKVE 964
            + +EE  + + E + L   L +++   E+L   K EK+ +  E  +++E+   ++++K +
Sbjct: 943  ELEEEKNKTIEEKTNLQQELNENKKIVEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQ 1002

Query: 965  LLEENRQLRIEVVNGVEKENRS-----------KSTLAALQAEMIEL-RQTNQVFQEENG 1012
            ++ EN++++ E +  +E++ +            K  L   + E IE+ ++ ++V  E N 
Sbjct: 1003 IINENKEIKEENIKSIEEKTQEINSLTTSIEELKGRLEESKGERIEIEKERDRVISELND 1062

Query: 1013 KMLDEK----------------------------NSLCRNVSDLKDAKSSAEDENSVMFH 1044
              L  +                            NSL   ++ L + K    +E  +   
Sbjct: 1063 IKLQNEGMKKQVEEAHNRMTEMQKSFEGSENEMINSLNNQITQLNE-KEKQMNEQVMALQ 1121

Query: 1045 DVLALSNLNLV-YEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENV 1103
              L+ SN+NL   +    E+  +   + E    +    N +N+E+  + +  E  + E  
Sbjct: 1122 TQLSQSNINLEEVKKDLIESQNKYTQINEEKDCVEQERNKINEEYKTVNEELEKNKKE-- 1179

Query: 1104 YLNESIERMDKELLEMDKR----------LKAAETSNAEFSRHIEELKME---------- 1143
             LN+   + D E+LE++K           LK  +T+  E  + +EE K +          
Sbjct: 1180 -LNDLQTKYDNEILELNKNKDELNSLINNLKEEKTNLEEQVKKMEEEKSKLITELSNGSD 1238

Query: 1144 -----QEESTKIKENLD-------------RQILEQSENCMNHKKEIEHLNEANETLQFE 1185
                  EE T+ K+  +             ++I E+    +N  KEI+   E  E ++ E
Sbjct: 1239 GVSKLNEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIK---EEKEKIEEE 1295

Query: 1186 MKTLLHEVEQHRVREEALNLEL---------LNKENEFKLWEN--EAAAFYHDLQMSSIC 1234
             K LL E+E+ +     L  E+         + ++N+  + +N  E A F  + +     
Sbjct: 1296 KKELLKEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKE 1355

Query: 1235 LALLESKVSELT--------GVCKILDDESSAKSLENEHMREIISLLESEIGGLKEQLSA 1286
            L  ++ + S+L         G+ K L++E    + E E +R+ +  L+ E   ++++L  
Sbjct: 1356 LNQIKEEKSKLITDLSNGNDGLSK-LNEEIETINKEKEGIRKELESLKEENNKIQDELEQ 1414

Query: 1287 YVPLVSSLKEDFNSLEH--------ISLLWTKRNSVVGNG---AQKDVVIETCLRK-HSH 1334
                +S +KE+   L H        I+ L    N +  +     +K+V ++  + K  S 
Sbjct: 1415 KNQELSKVKEEKEKLIHDLTNGNDGINQLNEDLNQIKNDKEELTEKNVQLQNEINKLKSE 1474

Query: 1335 QSARENEIVLIPDGVSDLLTLQTRIRAVEKIMMEELKRRVKQKSLTTESTPYSSLEIATY 1394
                 N +    +G+  +      I+     +++++K+  ++K    E   ++  E+   
Sbjct: 1475 NEELSNNLSFEKEGLKQVNEEVNAIKEERDELVKQIKKIEEEKRKVEEELNFNGSEVNEQ 1534

Query: 1395 PKVENRKKEIELVEENVFDRNSWRKKPKIRLLMKDIPLDRNVDDQNSKYLKREHRRTNDH 1454
                N +KE    E N   +N    + KI  + ++         + S  +K++       
Sbjct: 1535 IAQINNEKEQLNQECNELKQNLKELQSKIEEIEQE---------KESNEIKKKE------ 1579

Query: 1455 VLELCENNEHEPLSAPTVDHAMICHRSDDSGRYLNYSSELD-IEKELGVDKLELSKSVKE 1513
              EL E  E             I  + +D     N   E++ IEKEL           +E
Sbjct: 1580 --ELQELQEE------------ITEKDND---IKNLKEEIERIEKEL-----------QE 1611

Query: 1514 KTEDDKRRILERLSSDGQKLAILKMALQDLKKKTETKKKSKQGNDIEYETVKRHIEEVEE 1573
            K ED     +E++S++ ++L  LK  L + ++  E +KK K+    E+E  K  +    +
Sbjct: 1612 KEED-----MEQMSNNTEELEELKNKLTETQRLLEEEKKEKESISNEFEETKEQVLVELQ 1666

Query: 1574 AVMQQVSINDQMAKNVEEGASSLDREIPRRGS--EQIGKLQFEVQNIQYILLKLAEENNN 1631
             V  +++  +++ +  E     L   I +  S  E+  +   EV  +++ L +L  EN +
Sbjct: 1667 RVNNEMNKMNEIKQEDENEKEELQEHINKLKSQIERENEQLKEVSKLKWELSELKTENES 1726

Query: 1632 KVKNRISRKTGIL 1644
             +K  I  K  +L
Sbjct: 1727 -MKQMIMNKKSLL 1738



 Score =  217 bits (552), Expect = 3e-54
 Identities = 333/1676 (19%), Positives = 720/1676 (42%), Gaps = 333/1676 (19%)

Query: 136  RSKKNERSSEESNGEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARG 195
            R   ++R+S E+ G   +   A + + S+  A     +E   +++    + NK   N   
Sbjct: 140  RKSFSKRNSTENTGHSSSEHSATSSLASETTA-----EEVNRSVNAQIEEENKRLQNEN- 193

Query: 196  LDDRASEAEIQVEILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIEAKNLKQ 255
             ++   + + Q  +LK  +      K   E+L N+  + I   + M ++ D +    L +
Sbjct: 194  -EELKKKCDAQDSLLKTKMKSEMEAKKKVEILENEKKDLI---DKMANENDGMS--KLNE 247

Query: 256  ELTRVVVQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAE 315
            ELT++  +K+++               N++   ++    +N+++ + + + +     L +
Sbjct: 248  ELTQIKNEKESI--------------NNELIQTKQEKESINNELTQLKTDNDQKENELNQ 293

Query: 316  MNEERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLE------ISEKHR 369
            +  E+D +   ++   E+  K+ NE+  +++  E+ +N+++++ +K+E      I+E   
Sbjct: 294  VRHEKDEVIEKFNTSKEENEKIMNELSQLKQEKEEKENELKEQVKKMEEEKSKLITELSN 353

Query: 370  GM--LEKSNQNL---QLEAENL----------VQRIASKDHELLEKHTEIERLQTLMHGE 414
            G   + K N+ L   + E E +           +RI  + ++++ ++ EI+  +  +  E
Sbjct: 354  GSDGISKLNEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEE 413

Query: 415  HSNFI-----------QIESALQALQ------------------KLYSQSQKEQRNLALE 445
                +           Q+++ +  +Q                  K  ++ ++EQ NL  E
Sbjct: 414  KKELLKEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKE 473

Query: 446  LK----------------YGLLLLKDLELSK------QDFKEE------MQGIVEENKTL 477
            L                   +   K+ EL+K      Q F E+      +  IVEE   L
Sbjct: 474  LNQIKEEKQKTENEKNELVDVKTQKENELNKLKEEKEQIFNEKTTIENSLNQIVEEKNKL 533

Query: 478  HELNFSSTRSL-------KKQQMEISKLKEIKEKLEREFHTSTEESNVLQRETHQIKDDI 530
             E   S  + L         +++EI+K+ E K +L+ ++ T  +E   +Q+E +QIK + 
Sbjct: 534  TEEKESIKQELDSIKADNSTKELEINKINEEKNQLQNDYDTVQQEKENIQKELNQIKIEK 593

Query: 531  QHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNEN---FMLKETCKKEHSEKEALREK-- 585
                E    + E+ Q +    +  A  + D+ N N     L E   K   EKE +  +  
Sbjct: 594  SQKEEELNKIKEEKQQV---EDEKAKLITDIANGNDGLTKLNEVIDKLKDEKENISNELN 650

Query: 586  ---------SKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILAD 636
                     S + N+   E    E   + LN+E   L   + +I++  Q +++EK+++  
Sbjct: 651  QIKNERDNISNEFNKTKEEIKQKENETIQLNEEKSVLLNELNQIKEEKQKIEDEKAVIQQ 710

Query: 637  EKSTLLSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNN 696
            EK   +++L           E+ TV+E  L+  K E +       ++E+      DEK  
Sbjct: 711  EKENEITKLN----------EDKTVIENELNQIKTEKQ-------EIENELNQTKDEKQK 753

Query: 697  LQNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASIL---VQ 753
            +++E+S LI++L    + +S L +++T  +++  +V  +    +NQ++  FAS      Q
Sbjct: 754  IEDEKSKLITELSNGNDGISKLNEELTQTKQEKENVLNE----LNQIKNEFASFKEQNTQ 809

Query: 754  KENH-SNHKHSSEARLANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQNCIEE 812
            KEN   +  +  +  L    N V  L+EE+  G +  E    +    Q +  I+    E+
Sbjct: 810  KENELKDENNKVQQELEQKNNEVSKLEEEK--GNISNELSNTKQELEQKKQEIITITQEK 867

Query: 813  LELKNFVLLTECEKLVEASKFSDKVISELE--SENLMQLIEEEFLLHRIRKFKMDIHKVC 870
             E +N   L E  K +E  K   K+I+EL   S+ + +L EE   L + ++ K +I K  
Sbjct: 868  EEKEN--ELKEQVKKIEEEK--SKLITELSNGSDGISKLNEE---LTQTKQEKEEIQKA- 919

Query: 871  GVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSVLLGSLQQH 930
                          +++E+  + RI  +++ ++ +  + +EE  + + E + L   L ++
Sbjct: 920  --------------LEEEKEKLERIETELKEIKEAKQELEEEKNKTIEEKTNLQQELNEN 965

Query: 931  QSEGEKL---KLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKENRSK 987
            +   E+L   K EK+ +  E  +++E+   ++++K +++ EN++++ E +  +E++ +  
Sbjct: 966  KKIVEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEENIKSIEEKTQEI 1025

Query: 988  STLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVL 1047
            ++L         + +     +E  G+ ++ +    R +S+L D K               
Sbjct: 1026 NSLTT------SIEELKGRLEESKGERIEIEKERDRVISELNDIK--------------- 1064

Query: 1048 ALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENV-YLN 1106
             L N  +  ++    N + +                       ++K+FE  E E +  LN
Sbjct: 1065 -LQNEGMKKQVEEAHNRMTE-----------------------MQKSFEGSENEMINSLN 1100

Query: 1107 ESIERMDKELLEMDKRLKAAETSNAEFSRHIEELKMEQEESTKIKENLDRQILEQSENCM 1166
              I +++++  +M++++ A +T  ++ + ++EE+K +  ES    +N   QI E+ ++C+
Sbjct: 1101 NQITQLNEKEKQMNEQVMALQTQLSQSNINLEEVKKDLIES----QNKYTQINEE-KDCV 1155

Query: 1167 NHKKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLELLNKENEFKLWENEAAAFYH 1226
              ++     N+ NE    E KT+  E+E+++     L  +  N+  E    ++E      
Sbjct: 1156 EQER-----NKINE----EYKTVNEELEKNKKELNDLQTKYDNEILELNKNKDE------ 1200

Query: 1227 DLQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMREIISLLESEIGGLKEQLSA 1286
               ++S+   L E K + L    K +++E S    E  +  + +S L  E+   K++   
Sbjct: 1201 ---LNSLINNLKEEK-TNLEEQVKKMEEEKSKLITELSNGSDGVSKLNEELTQTKQEKEE 1256

Query: 1287 YVPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQK-DVVIETCLRKHSHQSARENEIVLI 1345
                ++S+KE+   +E         N  +    +K +   +  L++   +    N++   
Sbjct: 1257 INNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQL--- 1313

Query: 1346 PDGVSDLLTLQTRIRAVEKIMMEEL--------KRRVKQKSLTTESTPYSSLEIATYPKV 1397
                +++ T+QTR++ +E+   E +        K + +Q++L  E       +      +
Sbjct: 1314 ---QNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKSKLITDL 1370

Query: 1398 ENRKKEIELVEENVFDRNSWRKKPKIRLLMKDIPLDRN-----VDDQNSKYLKREHRRT- 1451
             N    +  + E +   N  ++K  IR  ++ +  + N     ++ +N +  K +  +  
Sbjct: 1371 SNGNDGLSKLNEEIETIN--KEKEGIRKELESLKEENNKIQDELEQKNQELSKVKEEKEK 1428

Query: 1452 --------NDHVLELCEN-----NEHEPLSAPTVDHAMICHRSDDSGRYLNYSSELDIEK 1498
                    ND + +L E+     N+ E L+   V      ++       L  S+ L  EK
Sbjct: 1429 LIHDLTNGNDGINQLNEDLNQIKNDKEELTEKNVQLQNEINKLKSENEEL--SNNLSFEK 1486

Query: 1499 E-----------LGVDKLELSKSVKEKTEDDKRRILERLSSDG----------------- 1530
            E           +  ++ EL K +K K E++KR++ E L+ +G                 
Sbjct: 1487 EGLKQVNEEVNAIKEERDELVKQIK-KIEEEKRKVEEELNFNGSEVNEQIAQINNEKEQL 1545

Query: 1531 -QKLAILKMALQDLKKKTETKKKSKQGNDIEYETVKRHIEEVEEAVMQQVSINDQMAKNV 1589
             Q+   LK  L++L+ K E  ++ K+ N+I+    K  ++E++E + ++    D   KN+
Sbjct: 1546 NQECNELKQNLKELQSKIEEIEQEKESNEIK---KKEELQELQEEITEK----DNDIKNL 1598

Query: 1590 EEGASSLDREIPRRGSEQIGKLQFEVQNIQYILLKLAE-----ENNNKVKNRISRK 1640
            +E    +++E+  +  E + ++    + ++ +  KL E     E   K K  IS +
Sbjct: 1599 KEEIERIEKELQEK-EEDMEQMSNNTEELEELKNKLTETQRLLEEEKKEKESISNE 1653



 Score =  209 bits (532), Expect = 6e-52
 Identities = 271/1343 (20%), Positives = 577/1343 (42%), Gaps = 164/1343 (12%)

Query: 31   ENLTDIDTKVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHAM 90
            E + +    +K   K IEEE +      +   +++ ++ +  +E  +      E  +   
Sbjct: 373  EEINNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQ 432

Query: 91   GELRHAHKTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKNERSSEESN-G 149
             E+      M E    +   I +++        + E+        + +K +  +E++   
Sbjct: 433  NEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEKNELV 492

Query: 150  EVQTLRE-ALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDDRASEAEIQVE 208
            +V+T +E  L K++ +K+ +F +      +L+++  + NK                 + E
Sbjct: 493  DVKTQKENELNKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTE--------------EKE 538

Query: 209  ILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIEAKNLKQELTRVVVQKDTVL 268
             +K+ L  +KAD    E+  N+  E   +L++        E +N+++EL ++ ++K    
Sbjct: 539  SIKQELDSIKADNSTKELEINKINEEKNQLQNDYDTVQQ-EKENIQKELNQIKIEKSQKE 597

Query: 269  LQYKQCLEKIPMLENK-------IALAEENSRMLNDQIERTELEVETLRKNLAEMNEERD 321
             +  +  E+   +E++       IA   +    LN+ I++ + E E +   L ++  ERD
Sbjct: 598  EELNKIKEEKQQVEDEKAKLITDIANGNDGLTKLNEVIDKLKDEKENISNELNQIKNERD 657

Query: 322  SLSVLYHHCLEKISKMENEILHVQENAEQL---KNKIEKEAEKLEISEKHRGMLEKSNQN 378
            ++S  ++   E+I + ENE + + E    L    N+I++E +K+E  EK     EK N+ 
Sbjct: 658  NISNEFNKTKEEIKQKENETIQLNEEKSVLLNELNQIKEEKQKIE-DEKAVIQQEKENEI 716

Query: 379  LQLE-----AENLVQRIASKDHELLEKHTEIERLQTLMHGEHSNFI-QIESALQALQKL- 431
             +L       EN + +I ++  E+  +  + +  +  +  E S  I ++ +    + KL 
Sbjct: 717  TKLNEDKTVIENELNQIKTEKQEIENELNQTKDEKQKIEDEKSKLITELSNGNDGISKLN 776

Query: 432  --YSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSLK 489
               +Q+++E+ N          +L +L   K +F    +   ++   L + N    + L+
Sbjct: 777  EELTQTKQEKEN----------VLNELNQIKNEFASFKEQNTQKENELKDENNKVQQELE 826

Query: 490  KQQMEISKLKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQSLGL 549
            ++  E+SKL+E K  +  E   + +E   L+++  +I    Q   E+   + EQ++ +  
Sbjct: 827  QKNNEVSKLEEEKGNISNELSNTKQE---LEQKKQEIITITQEKEEKENELKEQVKKIEE 883

Query: 550  NPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDMNEVLMENACMEFSLLGLNDE 609
              +     + +  +    L E   +   EKE +++  ++  E                 +
Sbjct: 884  EKSKLITELSNGSDGISKLNEELTQTKQEKEEIQKALEEEKE-----------------K 926

Query: 610  LDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESMQKILENNTVLEKSLSDA 669
            L+ +   +KEI++  Q L+EEK+   +EK+ L           Q++ EN  ++E+ L+  
Sbjct: 927  LERIETELKEIKEAKQELEEEKNKTIEEKTNL----------QQELNENKKIVEE-LTQT 975

Query: 670  KIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQ-LEIVEEKLSNLEKKVTNLEE- 727
            K E E +  +   +++  K + +EKN + NE   +  + ++ +EEK   +    T++EE 
Sbjct: 976  KQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEENIKSIEEKTQEINSLTTSIEEL 1035

Query: 728  ---------KYADVEKDKESAVNQVEELFASILVQKENHSNHKHSSEARLANLENIVRVL 778
                     +  ++EK+++  ++++ +    I +Q E        +  R+  ++      
Sbjct: 1036 KGRLEESKGERIEIEKERDRVISELND----IKLQNEGMKKQVEEAHNRMTEMQKSFEGS 1091

Query: 779  QEE---QRLGKVEFEQELDRVVNAQIEMFILQNCIEELELKNFVLLTECEKLVEASKFSD 835
            + E       ++    E ++ +N Q+    LQ    +L   N  L    + L+E+     
Sbjct: 1092 ENEMINSLNNQITQLNEKEKQMNEQV--MALQT---QLSQSNINLEEVKKDLIESQNKYT 1146

Query: 836  KVISELES-ENLMQLIEEEF--LLHRIRKFKMDIHKVCGVLQIDSDGGGDNEI-----KK 887
            ++  E +  E     I EE+  +   + K K +++        D     DNEI      K
Sbjct: 1147 QINEEKDCVEQERNKINEEYKTVNEELEKNKKELN--------DLQTKYDNEILELNKNK 1198

Query: 888  EEIP--ISRILDKIESLESSLVKSQEENQQLLVE-----------NSVLLGSLQQHQ--- 931
            +E+   I+ + ++  +LE  + K +EE  +L+ E           N  L  + Q+ +   
Sbjct: 1199 DELNSLINNLKEEKTNLEEQVKKMEEEKSKLITELSNGSDGVSKLNEELTQTKQEKEEIN 1258

Query: 932  SEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKENRSKSTLA 991
            +E   +K EKK +E+E   +  +N  ++++K ++ EE ++L  E+    E  N+ ++ + 
Sbjct: 1259 NELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNEIN 1318

Query: 992  ALQAEMIELRQTNQVF----QEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVL 1047
             +Q  M E+ + NQ       +E  K  +E+ +L + ++ +K+ KS    + S   +   
Sbjct: 1319 TIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKSKLITDLS---NGND 1375

Query: 1048 ALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDL-------NQEFGVLRKNFEVKEA 1100
             LS LN   E   T N  EK  + + L +L   NN +       NQE   +++  E    
Sbjct: 1376 GLSKLN---EEIETINK-EKEGIRKELESLKEENNKIQDELEQKNQELSKVKEEKEKLIH 1431

Query: 1101 ENVYLNESIERMDKELLEMDKRLKAAETSNAEFSRHIEELKMEQEESTKIKENLDRQILE 1160
            +    N+ I +++++L ++    +     N +    I +LK E EE       L   +  
Sbjct: 1432 DLTNGNDGINQLNEDLNQIKNDKEELTEKNVQLQNEINKLKSENEE-------LSNNLSF 1484

Query: 1161 QSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLELLNKENEFKLWENE 1220
            + E      +E+  + E  + L  ++K +  E E+ +V EE LN        +     NE
Sbjct: 1485 EKEGLKQVNEEVNAIKEERDELVKQIKKI--EEEKRKVEEE-LNFNGSEVNEQIAQINNE 1541

Query: 1221 AAAFYHDLQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMREIISLLESEIGGL 1280
                  +       L  L+SK+ E+    +  +     K  E + ++E I+  +++I  L
Sbjct: 1542 KEQLNQECNELKQNLKELQSKIEEIE---QEKESNEIKKKEELQELQEEITEKDNDIKNL 1598

Query: 1281 KEQLSAYVPLVSSLKEDFNSLEH 1303
            KE++      +   +ED   + +
Sbjct: 1599 KEEIERIEKELQEKEEDMEQMSN 1621



 Score =  171 bits (432), Expect = 2e-40
 Identities = 228/1109 (20%), Positives = 474/1109 (42%), Gaps = 159/1109 (14%)

Query: 138  KKNERSSEESNGEVQTLRE-ALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGL 196
            K+ ++  E+    +Q  +E  + K+  DK  +  +  +      ++E +LN+ ++  + +
Sbjct: 695  KEEKQKIEDEKAVIQQEKENEITKLNEDKTVIENELNQIKTEKQEIENELNQTKDEKQKI 754

Query: 197  DDRASEAEIQ-------VEILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIE 249
            +D  S+   +       +  L E L Q K +K+      NQ     A  +   +QK+N E
Sbjct: 755  EDEKSKLITELSNGNDGISKLNEELTQTKQEKENVLNELNQIKNEFASFKEQNTQKEN-E 813

Query: 250  AKNLKQELTRVVVQKDTVLLQYKQCLEKIP--MLENKIALAEENSRMLNDQIERTELEVE 307
             K+   ++ + + QK+  + + ++    I   +   K  L ++   ++    E+ E E E
Sbjct: 814  LKDENNKVQQELEQKNNEVSKLEEEKGNISNELSNTKQELEQKKQEIITITQEKEEKENE 873

Query: 308  TLRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEK 367
             L++ + ++ EE+  L     +  + ISK+  E+   ++  E+++  +E+E EKLE  E 
Sbjct: 874  -LKEQVKKIEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEIQKALEEEKEKLERIET 932

Query: 368  HRGMLEKSNQNLQLEAENLVQRIASKDHELLEKHTEIERL-QTLMHGEHSNFIQIESALQ 426
                ++++ Q L+ E    ++   +   EL E    +E L QT    E     +I + L 
Sbjct: 933  ELKEIKEAKQELEEEKNKTIEEKTNLQQELNENKKIVEELTQTKQEKE-----EINNELN 987

Query: 427  ALQKLYSQSQKEQRNLALELK-YGLLLLKDLELSKQDFK------EEMQGIVEENK---- 475
            ++++   + ++E+  +  E K      +K +E   Q+        EE++G +EE+K    
Sbjct: 988  SIKEEKKRIEEEKNQIINENKEIKEENIKSIEEKTQEINSLTTSIEELKGRLEESKGERI 1047

Query: 476  --------TLHELNFSSTRS--LKKQQMEI-SKLKEIKEKLEREFHTSTEESNVLQRETH 524
                     + ELN    ++  +KKQ  E  +++ E+++  E    +  E  N L  +  
Sbjct: 1048 EIEKERDRVISELNDIKLQNEGMKKQVEEAHNRMTEMQKSFEG---SENEMINSLNNQIT 1104

Query: 525  QIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALRE 584
            Q+ +  + +NE+  A+  QL    +N       + + QN+   + E       E+  + E
Sbjct: 1105 QLNEKEKQMNEQVMALQTQLSQSNINLEEVKKDLIESQNKYTQINEEKDCVEQERNKINE 1164

Query: 585  KSKDMNEVLMEN--------ACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILAD 636
            + K +NE L +N           +  +L LN   D L   +  +++    L+E+   + +
Sbjct: 1165 EYKTVNEELEKNKKELNDLQTKYDNEILELNKNKDELNSLINNLKEEKTNLEEQVKKMEE 1224

Query: 637  EKSTLLSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCC-------KL 689
            EKS L+++L   ++ + K+ E  T  ++   +   E   ++ +   +E+         K 
Sbjct: 1225 EKSKLITELSNGSDGVSKLNEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKE 1284

Query: 690  LNDEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAV--------- 740
            + +EK  ++ E+  L+ ++E  +E  + L+ ++  ++ +  ++E+  +  +         
Sbjct: 1285 IKEEKEKIEEEKKELLKEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIAK 1344

Query: 741  ------------NQVEELFASILVQKENHSN--------------HKHSSEARLANLENI 774
                        NQ++E  + ++    N ++               K      L +L+  
Sbjct: 1345 FKEEQENLQKELNQIKEEKSKLITDLSNGNDGLSKLNEEIETINKEKEGIRKELESLKEE 1404

Query: 775  VRVLQEE-----QRLGKVEFEQEL---------DRVVNAQIEMFILQNCIEELELKNFVL 820
               +Q+E     Q L KV+ E+E          D +     ++  ++N  EEL  KN  L
Sbjct: 1405 NNKIQDELEQKNQELSKVKEEKEKLIHDLTNGNDGINQLNEDLNQIKNDKEELTEKNVQL 1464

Query: 821  LTECEKLVEASKFSDKVISELESENLMQLIEE--------EFLLHRIRKFKMDIHKVCGV 872
              E  KL   ++     +S  E E L Q+ EE        + L+ +I+K + +  KV   
Sbjct: 1465 QNEINKLKSENEELSNNLS-FEKEGLKQVNEEVNAIKEERDELVKQIKKIEEEKRKVEEE 1523

Query: 873  LQIDSDGGGD----------------NEIKKEEIPISRILDKIES-LESSLVKSQEENQQ 915
            L  +     +                NE+K+    +   +++IE   ES+ +K +EE Q+
Sbjct: 1524 LNFNGSEVNEQIAQINNEKEQLNQECNELKQNLKELQSKIEEIEQEKESNEIKKKEELQE 1583

Query: 916  LLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQ--KDKV----ELLEEN 969
            L  E +     ++  + E E+++ E +  E++ E M      L+  K+K+     LLEE 
Sbjct: 1584 LQEEITEKDNDIKNLKEEIERIEKELQEKEEDMEQMSNNTEELEELKNKLTETQRLLEEE 1643

Query: 970  RQLRIEVVNGVEKENRSKSTLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLK 1029
            ++ +  + N  E E   +  L  LQ    E+ + N++ QE+     +EK  L  +++ L 
Sbjct: 1644 KKEKESISN--EFEETKEQVLVELQRVNNEMNKMNEIKQEDE----NEKEELQEHINKL- 1696

Query: 1030 DAKSSAEDENSVMFHDVLALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFG 1089
              KS  E EN      +  +S L        TEN   K+ +      L + ++       
Sbjct: 1697 --KSQIEREN----EQLKEVSKLKWELSELKTENESMKQMIMNKKSLLDNTDD------- 1743

Query: 1090 VLRKNFEVKEAENVYLNESIERMDKELLE 1118
             +  + E    ++V++   +E +D+E L+
Sbjct: 1744 FILMSLEYLYFDSVWVTLKMELLDEEDLD 1772



 Score =  145 bits (367), Expect = 8e-33
 Identities = 186/843 (22%), Positives = 357/843 (42%), Gaps = 69/843 (8%)

Query: 31   ENLTDIDTKVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHAM 90
            E + +    +K   K IEEE +      +   + + E +K +EE  +   +L    +   
Sbjct: 980  EEINNELNSIKEEKKRIEEEKNQIINENK---EIKEENIKSIEEKTQEINSLTTSIEELK 1036

Query: 91   GELRHAHKTMPEAFPNSAYYI--LNDDSPCGSLGPDAESHTSARPTHRSKKNERSSEES- 147
            G L  +     E        I  LND                 R T   K  E S  E  
Sbjct: 1037 GRLEESKGERIEIEKERDRVISELNDIKLQNEGMKKQVEEAHNRMTEMQKSFEGSENEMI 1096

Query: 148  ---NGEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDDRASEAE 204
               N ++  L E   +M     AL  Q  +S  NL +++ DL ++QN    +++     E
Sbjct: 1097 NSLNNQITQLNEKEKQMNEQVMALQTQLSQSNINLEEVKKDLIESQNKYTQINEEKDCVE 1156

Query: 205  IQVEILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIEAKNLKQELTRVVVQK 264
             +   + E    +  + +  +   N  L+T    E +   K+  E  +L   L     +K
Sbjct: 1157 QERNKINEEYKTVNEELEKNKKELND-LQTKYDNEILELNKNKDELNSLINNLKE---EK 1212

Query: 265  DTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEERDSLS 324
              +  Q K+  E+   L  +++   +    LN+++ +T+ E E +   L  + EE+    
Sbjct: 1213 TNLEEQVKKMEEEKSKLITELSNGSDGVSKLNEELTQTKQEKEEINNELNSIKEEK---- 1268

Query: 325  VLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKL--EISEKHRGMLEKSNQNLQLE 382
                   ++I + +N+I++  +  ++ K KIE+E ++L  EI ++  G     N  LQ  
Sbjct: 1269 -------KRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEG-----NNQLQ-- 1314

Query: 383  AENLVQRIASKDHELLEKHTEIERLQTLMHGEHSNFIQIESALQALQKLYSQSQKEQRNL 442
              N +  I ++  E+ EK+ EI      +   +    + +   + LQK  +Q ++E+  L
Sbjct: 1315 --NEINTIQTRMKEIEEKNQEI------ICDNNKEIAKFKEEQENLQKELNQIKEEKSKL 1366

Query: 443  ALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEISKLKEIK 502
              +L  G   L  L    +   +E +GI +E ++L E N      L+++  E+SK+KE K
Sbjct: 1367 ITDLSNGNDGLSKLNEEIETINKEKEGIRKELESLKEENNKIQDELEQKNQELSKVKEEK 1426

Query: 503  EKLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQ 562
            EKL  +     +  N L  + +QIK+D + L E+   +  ++       N   +   +L 
Sbjct: 1427 EKLIHDLTNGNDGINQLNEDLNQIKNDKEELTEKNVQLQNEI-------NKLKSENEELS 1479

Query: 563  NENFMLKETCKKEHSEKEALREKSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQ 622
            N     KE  K+ + E  A++E   + +E++ +   +E     + +EL+     V E  Q
Sbjct: 1480 NNLSFEKEGLKQVNEEVNAIKE---ERDELVKQIKKIEEEKRKVEEELNFNGSEVNE--Q 1534

Query: 623  FCQVLQEEKSI--LADEKSTLLSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKS 680
              Q+  E++ +    +E    L +LQ   E +++  E+N + +K       E + L+ + 
Sbjct: 1535 IAQINNEKEQLNQECNELKQNLKELQSKIEEIEQEKESNEIKKKE------ELQELQEEI 1588

Query: 681  GDLEDCCKLLNDEKNNLQ---NERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKE 737
             + ++  K L +E   ++    E+   + Q+    E+L  L+ K+T  +    + +K+KE
Sbjct: 1589 TEKDNDIKNLKEEIERIEKELQEKEEDMEQMSNNTEELEELKNKLTETQRLLEEEKKEKE 1648

Query: 738  SAVNQVEELFASILVQKENHSNHKHSSEARLANLENIVRVLQEEQRLGKVEFEQELDRVV 797
            S  N+ EE    +LV+ +  +N  +         EN    LQE     K + E+E +++ 
Sbjct: 1649 SISNEFEETKEQVLVELQRVNNEMNKMNEIKQEDENEKEELQEHINKLKSQIERENEQLK 1708

Query: 798  NAQIEMFILQNCIEELELKNFVLLTECEKLVEASKFSDKVISELESENL-----MQLIEE 852
                  + L     E E    +++ +   L     F    +  L  +++     M+L++E
Sbjct: 1709 EVSKLKWELSELKTENESMKQMIMNKKSLLDNTDDFILMSLEYLYFDSVWVTLKMELLDE 1768

Query: 853  EFL 855
            E L
Sbjct: 1769 EDL 1771


>UniRef100_UPI0000437332 UPI0000437332 UniRef100 entry
          Length = 2932

 Score =  221 bits (563), Expect = 1e-55
 Identities = 353/1730 (20%), Positives = 735/1730 (42%), Gaps = 247/1730 (14%)

Query: 59   EMYYKKRPELMKLVEEFYRAYRALAERYDHAMGELRHAHKTMPEAFPNSAYYILNDDSPC 118
            +M  K++  L K   E Y+    L ++ ++ + E++   + + +   N            
Sbjct: 5    DMLEKEKHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITI--------- 55

Query: 119  GSLGPDAESHTSARPTHRSKKNERSSEESNGEVQTLREALAK----MQSDKDALFLQYQE 174
                   E H       + K+ +   ++   E+Q L++ L K    +  D+  L L+  E
Sbjct: 56   -------EMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLRQSE 108

Query: 175  SLENLSKMETDLN---KAQNNARGLDDRASEAEIQVEILKESLMQLKADKDAGEVLYNQC 231
                L K +T++N   +   N R L D+  E   ++E  K+ + + + + D      ++ 
Sbjct: 109  ----LDKQQTNMNDIIETMKNERKLLDKDKE---EMEEQKQEMEKERDNMDQSIKSLDED 161

Query: 232  LETIARLESMLSQKDN-IEA--KNLKQELTRVVVQKDTV------LLQYKQCLEKIPMLE 282
            L+ +   + ++ ++ N +E   K+L ++L  + +QK  +      L Q K  LE+     
Sbjct: 162  LKMMKLQKQVIEEEKNKLEQMKKSLDEDLKMMKLQKQVIEEEKSKLKQMKIELEREADEI 221

Query: 283  NKIALAEENSRMLNDQI-ERTELEVETLRKNLAEMNEERDSLSVLYHHCLEKISKMENEI 341
             K+    +N R + +++ E  + E E L ++    N+  D + V     L  I +  + +
Sbjct: 222  RKVKEETQNERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANESTLADILRERSNL 281

Query: 342  LHVQENAEQLKNKIEKEAEKLEISE-----------KHRGMLEKSNQNLQLEAENLVQRI 390
              ++EN  +    +E + EK+ + E           K +   EK   N++ E   +++ +
Sbjct: 282  QEMRENISKQTEDVENKKEKIRLREEKLKQLQAEIHKQQSETEKEKSNIERERAAIIKDV 341

Query: 391  ASKDHELLEKHTEIERL---QTLMHGEHSNFIQIESALQ----ALQKLYSQSQKEQRNLA 443
                 +++    + E L   +     E     Q+++ L+     ++K+  ++Q E++ + 
Sbjct: 342  EDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVE 401

Query: 444  LELKYGLLLL-----KDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEISKL 498
             E+    +       K L  +K++ +E+ Q + +E   + +   S  ++LK  +++   +
Sbjct: 402  -EMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVI 460

Query: 499  KEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASV 558
            +E K KLE+      +E++    E  +IK++ Q+  +R + M E+L+       SF    
Sbjct: 461  EEEKNKLEQMKIELEKEAD----EIRKIKEETQNERQRLEKMTEELKK---EKESFTHLA 513

Query: 559  RDLQNE----------NFMLKETCKKEHSEKEALREK-SKDMNEVLMENACMEFSLLGLN 607
             D + E          N  L    +KE S  E +RE  SK   +   E   +        
Sbjct: 514  EDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLR----E 569

Query: 608  DELDGLRGTV---KEIQQFCQVLQEEKSILADEKSTL---------------------LS 643
            DEL+ L+  +   +EI++  + ++ ++ +L  EK  L                     L+
Sbjct: 570  DELEQLQAEIHKQQEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENLEKQRKIKLA 629

Query: 644  QLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSM 703
            ++Q   E ++K+ E  T+    + D K + E ++ K  +L+     + + +  L+ E+ +
Sbjct: 630  EIQKEREDLEKMNEKFTI---EIHDIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEI 686

Query: 704  LISQLEIVEEKLSNLEKKVTN-------LEEKYADVEKDKESAVNQVEELFASILVQKEN 756
            ++     ++ + S L+K+ TN       ++ +   ++KDKE    Q +E+      +KE 
Sbjct: 687  IMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEM------EKEK 740

Query: 757  H--SNHKHSSEARLANLENIVRVLQEEQ-RLGKVEFEQELDRVVNAQIEMFILQNCIEEL 813
            H     + S +  L  ++   +VL++E+ +L +++ E E + V   +I+  I QN  + L
Sbjct: 741  HDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEI-QNERQNL 799

Query: 814  ELKNFVLLTECEKLVEASKFSDKVISELESEN---LMQLIEEEFLLHRIR----KFKMDI 866
            E     L  E E L E +K +++V+ E++  N   L  ++ E+  L  +R    K   D+
Sbjct: 800  EKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDV 859

Query: 867  HKVCGVLQIDSD--GGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLV----EN 920
                  L++  D       EI K++  I +    IES  ++++K  E+ Q  ++    + 
Sbjct: 860  ENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDA 919

Query: 921  SVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQL---RIEVV 977
              L    +  ++E E LK  K  +E+E + + +  +  Q D+  + E   Q+   R E+ 
Sbjct: 920  ESLKLDREAFENEKEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDEIN 979

Query: 978  NGVEKENRSKSTLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAED 1037
            N +E+ NR       L  +  ++ +  +  Q +   +  EK+ L +  S+L   K   E 
Sbjct: 980  NLIEETNRKD---MVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEK 1036

Query: 1038 ENSVMFHDV------LALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVL 1091
            +      ++      L   N N+  E+   ++  E+  + +    L  L  ++      L
Sbjct: 1037 QKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQ--MNQKQDELDQLKTEIQNLQQEL 1094

Query: 1092 RKNFEVKEAENVYLNESIERMDKELLEMDKRLKAAETSNAEFSRHIEELKMEQEESTKIK 1151
             K  E+   +   L+     +DK+   M+  ++  +    +  +  EE++ +++E  K +
Sbjct: 1095 EKEKEIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKER 1154

Query: 1152 ENLD--RQILEQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALN-LELL 1208
            +N+D  R+ L++ +  M  +K++    E N+  Q +++      E  +++EE  N  + L
Sbjct: 1155 DNMDQSRKSLDEDQKKMKLQKQMFE-EEKNKLEQMKIELEREADEISKIKEETQNKRQRL 1213

Query: 1209 NKENEFKLWENEAAAFYHDLQMSSICLALLESKVSELTGVCKILDD-----ESSAKSLEN 1263
             K  E  + E E+ A             L E   +E     KILD+     ESS   L+ 
Sbjct: 1214 EKMTEELIREKESLAH------------LAEDTKTEK----KILDEMKVANESSMADLQR 1257

Query: 1264 -----EHMREIISLLESEIGGLKE-------QLSAYVPLVSSLKEDFNSLEHISLLWTKR 1311
                 E MRE IS L+  I   KE       +L      V   ++  N      +   K 
Sbjct: 1258 EKSILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQKKMNENITREMHEIKH 1317

Query: 1312 NSVVGNGAQKDV-VIETCLRKHSHQSARENEIVL-----IPDGVSDLLTLQTRIRAVEKI 1365
                 N  Q ++  ++T ++    +  +E EI++     +    S+L   QT +  + + 
Sbjct: 1318 QEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMET 1377

Query: 1366 MMEELKRRVKQKSLTTESTPYSSLEIATYPKVENRKKEIELVEENV-FDRNSWRKKPKIR 1424
            M  E K+  K K                  ++E +K+E+E   +N+   R S  +  K+ 
Sbjct: 1378 MKNERKQLDKDKE-----------------EMEEQKQEMEKERDNMDQSRKSLDEDLKMM 1420

Query: 1425 LLMKDIPLDRNVDDQNSK--YLKREHRRTNDHVLELCENNEH---------EPLSAPTVD 1473
             L K +     ++++ +K   +K E  R  D + ++ E  ++         E L     D
Sbjct: 1421 KLQKQV-----IEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKD 1475

Query: 1474 HAMICHRSDDSGRYLNYSSELDIEKELGVDKLELSKSVKEKTEDDKRRILERLSSDGQKL 1533
               + H ++D+ R  N   E+ +  E  +  L+  KS  E+ +++  +  E +  +  K+
Sbjct: 1476 ---VAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKI 1532

Query: 1534 AILKMALQDLKKKTETKKKSKQGNDIEYETVKRHIEEVEEAVMQQVSINDQMAKNVEEGA 1593
             + +  L+ L+ +       KQ ++ E E  K +IE    A+++ V        +++  A
Sbjct: 1533 RLREDELEQLQAEIH-----KQQSETEIE--KSNIERERAAIIKDVEDLQSKIISLDRDA 1585

Query: 1594 SS--LDREIPRRGSEQIGKLQFEVQNIQYILLKLAEENNNKVKNRISRKT 1641
             S  LDRE      E++ +++ E++     + K+  E  ++ + R+   T
Sbjct: 1586 ESLKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHE-RQRVEEMT 1634



 Score =  211 bits (538), Expect = 1e-52
 Identities = 368/1752 (21%), Positives = 728/1752 (41%), Gaps = 249/1752 (14%)

Query: 38   TKVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAE---RYDHAMGELR 94
            +K+K M   +E EAD   +  E    +R    K+ E   +    L+E   R +  + E++
Sbjct: 205  SKLKQMKIELEREADEIRKVKEETQNERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMK 264

Query: 95   HAHKT---------------------MPEAFPNSAYYILNDDSPCGSLGPDAESHTSARP 133
             A+++                       E   N    I   +     L   AE H     
Sbjct: 265  VANESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLREEKLKQL--QAEIHKQQSE 322

Query: 134  THRSKKN-ERSSEESNGEVQTLREALAKMQSDKDALFLQ---YQESLENLSKMETDLNKA 189
            T + K N ER       +V+ L+  +  +  D ++L L    ++   E L +M+T+L + 
Sbjct: 323  TEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELERE 382

Query: 190  QNNARGLDDRASEAEIQVEILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIE 249
                    D   + +++ +  ++ + ++ A  D  E + N+  +     E M  QK  +E
Sbjct: 383  A-------DEIEKIKLETQHERQRVEEMTA--DFMETMNNERKQLNKNKEEMQEQKQEME 433

Query: 250  AKNLKQELTRVVVQKDTVLLQYKQCL---EKIPMLENKIALAEENSRMLNDQIERTELEV 306
             +    + +R  + K+  +++ ++ +   EK  + + KI L +E      D+I + + E 
Sbjct: 434  KERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMKIELEKE-----ADEIRKIKEET 488

Query: 307  ETLRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISE 366
            +  R+ L +M EE       + H  E  +K E +IL         K K+  E+   ++ +
Sbjct: 489  QNERQRLEKMTEELKKEKESFTHLAED-TKTEKKILD--------KMKVANESLMADL-Q 538

Query: 367  KHRGMLEKSNQNLQLEAENLVQRIASKDHELLE-KHTEIERLQTLMHGEHSNFIQIESAL 425
            K +  LE+  +N+  + E+     + K+ E +  +  E+E+LQ  +H +     +I+  +
Sbjct: 539  KEKSNLEEMRENISKQTED-----SEKEKEKIRLREDELEQLQAEIHKQQ----EIKEKI 589

Query: 426  QALQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSST 485
            +A++      +KE+ +L    K    LL+  E  ++  K ++  I +E + L ++N    
Sbjct: 590  KAIESDRDMLEKEKHDLE---KTRSKLLRAKENLEKQRKIKLAEIQKEREDLEKMN---- 642

Query: 486  RSLKKQQMEISKLKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQ 545
               +K  +EI  +K  +E+++++           Q E  Q+K +IQ+L +  +   E + 
Sbjct: 643  ---EKFTIEIHDIKHQEEQMKQK-----------QDELDQLKTEIQNLQQELEKEKEIIM 688

Query: 546  SLGLNPNSFAASVRDLQNENFM-LKETCKKEHSEKEALREKSKDM-NEVLMENACMEFSL 603
                +      S  D Q  N   + ET K E  + +  +E++++   E+  E    + S 
Sbjct: 689  K-DRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSR 747

Query: 604  LGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESMQKILENNTVLE 663
              L+++L       K ++   QVL++EKS L   K  L  +   I +  ++I      LE
Sbjct: 748  KSLDEDL-------KMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLE 800

Query: 664  KSLSDAKIEFEGL---RIKSGDLEDCCKLLND--------EKNNLQNERSMLISQLEIVE 712
            K     K E E L     K+  + D  K+ N+        EK+NL+  R  +  Q E VE
Sbjct: 801  KMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVE 860

Query: 713  EKLSNL--------------EKKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHS 758
             K  NL               K+   +E++  ++E ++ + +  VE+L   I+    +  
Sbjct: 861  NKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAE 920

Query: 759  NHKHSSEARLANLENIVRVL-----QEEQRLGKVEFEQELDR------VVNAQIEMFILQ 807
            + K   EA   N + +++ +     +E   + K++ E + DR          Q +   + 
Sbjct: 921  SLKLDREA-FENEKEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDEIN 979

Query: 808  NCIEELELKNFVLLTECEKLVEASKF--SDKVISELESENLMQLIEE------------E 853
            N IEE   K+ VL  +   + E  K   SDK + E E  +L +   E            E
Sbjct: 980  NLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKE 1039

Query: 854  FLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEEN 913
              L  I+K + D+ K+   +  +      +EIK +E  +++  D+++ L++ +   Q   
Sbjct: 1040 NTLAEIQKEREDLEKMNENITREM-----HEIKHQEEQMNQKQDELDQLKTEI---QNLQ 1091

Query: 914  QQLLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLR 973
            Q+L  E  +++    Q      +L  ++  +    E M+ +   L KDK E+ E+ +++ 
Sbjct: 1092 QELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEME 1151

Query: 974  IEVVNGVEKENRSKSTLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKS 1033
                   E++N  +S   +L  +  +++   Q+F+EE  K+   K  L R   ++   K 
Sbjct: 1152 ------KERDNMDQSR-KSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKE 1204

Query: 1034 SAEDENSVMFHDVLALSNLNLVYEIFFTENMVEKRALCE-HLGNLSHLNNDLNQEFGVLR 1092
              +++   +      L            +   EK+ L E  + N S +  DL +E  +L 
Sbjct: 1205 ETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSM-ADLQREKSILE 1263

Query: 1093 ---------KNFEVKEAENVYLNE-SIERMDKELLEMDKRLKAAETSNAEFSRHIEE-LK 1141
                     K +   E E   L E  ++++  E+ +  K++    T      +H EE + 
Sbjct: 1264 EMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQKKMNENITREMHEIKHQEEQMN 1323

Query: 1142 MEQEESTKIK---ENLDRQILEQSENCMNHKKEIE----HLNEANETLQFEMKTLLHEVE 1194
             +Q+E  ++K   +NL +++ ++ E  M  + +++     L++    +   M+T+ +E +
Sbjct: 1324 QKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERK 1383

Query: 1195 QHRVREEALNLELLNKENEFKLWENEAAAFYHDLQMSSICLALLESKVSELTGVCKILDD 1254
            Q    +E +  +    E E    +    +   DL+M  +   ++E + ++L  +   L+ 
Sbjct: 1384 QLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELER 1443

Query: 1255 ESSAKSLENEHMREIISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLEHISLLWTKRNSV 1314
            E+       E  +    +LE     LK++      L    K + NSL+ + +        
Sbjct: 1444 EADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAEDTKREKNSLDEMKV-------- 1495

Query: 1315 VGNGAQKDVVIETCLRKHSHQSARENEIVLIPDGVSDLLTLQTRIRAVEKIMMEELKRRV 1374
                A +  + +    K + +  +EN    I     D+   + +IR  E   +E+L+  +
Sbjct: 1496 ----ANESSMADLQKEKSNLEEMKEN----ISKQTEDIEKEKDKIRLRED-ELEQLQAEI 1546

Query: 1375 -KQKSLT-TESTPYSSLEIATYPKVENRKKEIELVEENV----FDRNSWRKKPKIRLLMK 1428
             KQ+S T  E +       A    VE+ + +I  ++ +      DR ++  + K  L   
Sbjct: 1547 HKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENE-KEELKQM 1605

Query: 1429 DIPLDRNVDDQNSKYLKREH--RRTNDHVLELCE--NNEHEPLSAPTV-----DHAMICH 1479
               L+R  D+     L+ +H  +R  +   +  E  NNE + L    V        M   
Sbjct: 1606 KTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKK 1665

Query: 1480 RSDDSGRYLNYSSELDIEK------ELGVDKLELSKSVKEKTEDDKRRILERLSSDGQKL 1533
            R D      +   +L + K      E   +KLE  K   E+  D+  +I E   ++ Q L
Sbjct: 1666 RDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIGLEREADEISKIKEETQNERQNL 1725

Query: 1534 AILKMAL--------QDLKKKTETKKKSKQGND---IEYETVKRHIEEVEEAVMQQVS-- 1580
              +  AL        +++K+K +   K K  N+    + +  KR +EE+ E + +Q+   
Sbjct: 1726 EKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLADLQKEKRILEEMRENISKQIEDI 1785

Query: 1581 ---------INDQMAK---NVEEGASSLDREIPRRGSEQIGKLQFEVQNIQYILLKLAEE 1628
                       D++ K    V++  S +D E     SE+   ++ E QN+   L K +E+
Sbjct: 1786 ENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAAMIR-EKQNMMTELKKKSED 1844

Query: 1629 NNNKVKNRISRK 1640
               ++K  ++ K
Sbjct: 1845 VEMQMKEILTEK 1856



 Score =  204 bits (520), Expect = 1e-50
 Identities = 343/1681 (20%), Positives = 705/1681 (41%), Gaps = 273/1681 (16%)

Query: 33   LTDIDTKVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAE---RYDHA 89
            L D  +K++ M   +E EA    +  E    +R  L K+ E        LAE   + +  
Sbjct: 764  LEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQV 823

Query: 90   MGELRHAHKTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKNERSSEESNG 149
            + E++ A+++       +   IL + S    +  +    T        K+N R  E+   
Sbjct: 824  LDEMKVANES-------TLADILREKSNLEEMRENISKQTE--DVENKKENLRLRED--- 871

Query: 150  EVQTLREALAKMQSD--KDALFLQYQES--LENLSKMETDLNKAQNNARGLDDRASEAEI 205
            E++ L+  + K Q +  K+ + ++ + +  ++++  ++  +     +A  L       E 
Sbjct: 872  ELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFEN 931

Query: 206  QVEILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQ--KDNIEAKNLKQELTRVVVQ 263
            + E+LK+   +L+ + D  E +  +      R+E M +Q  KD  E  NL +E  R    
Sbjct: 932  EKEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDEINNLIEETNR---- 987

Query: 264  KDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEERDSL 323
            KD VL       EK   +E KI   + +  ML       E E   L K  +E+ + ++ L
Sbjct: 988  KDMVLN------EKNRDIEEKIKSIQSDKDML-------EKEKHDLEKTRSELYKVKEDL 1034

Query: 324  SVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQLEA 383
                 + L +I K   ++  + EN  +  ++I+ + E++   +     L+   QNLQ E 
Sbjct: 1035 EKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQEL 1094

Query: 384  ENLVQRIASKDHELLEKHTEIERLQTLMHGEHSNFIQIESALQALQKLYSQSQKEQRNLA 443
            E   + I     +L  + +E+++ QT M+            ++ ++    Q  K++    
Sbjct: 1095 EKEKEIIMKDRSQLDLRQSELDKQQTNMN----------DIMETMKNERKQLDKDK---- 1140

Query: 444  LELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEISKLKEIKE 503
                      +++E  KQ+ ++E   + +  K+L E         +  + E +KL+++K 
Sbjct: 1141 ----------EEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKI 1190

Query: 504  KLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQN 563
            +LERE             E  +IK++ Q+  +R + M E+L             +R+ ++
Sbjct: 1191 ELERE-----------ADEISKIKEETQNKRQRLEKMTEEL-------------IREKES 1226

Query: 564  ENFMLKETCKKEHSEKEALREKSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQF 623
               + ++T     +EK+ L ++ K  NE  M +   E S+      L+ +R  + +++++
Sbjct: 1227 LAHLAEDT----KTEKKIL-DEMKVANESSMADLQREKSI------LEEMRENISKLKEY 1275

Query: 624  CQVLQEEKSILADEKSTLLSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDL 683
                +E+  +  DE    L +LQ   +  QK +  N  + + + + K + E +  K  +L
Sbjct: 1276 IDNEKEKSKLREDE----LKKLQTEVQKQQKKMNEN--ITREMHEIKHQEEQMNQKQDEL 1329

Query: 684  EDCCKLLNDEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEE-------KYADVEKDK 736
            +     + + +  L+ E+ +++     ++ + S L+K+ TN+ +       +   ++KDK
Sbjct: 1330 DQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDK 1389

Query: 737  ESAVNQVEELFASILVQKENHSNHKHSSEARLANLENIVRVLQEEQ---RLGKVEFEQEL 793
            E    Q +E+      +++N    + S +  L  ++   +V++EE+      K+E E+E 
Sbjct: 1390 EEMEEQKQEMEK----ERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREA 1445

Query: 794  DRV----VNAQIEMFILQNCIEELELKNFVLLTECEKLVEASKFSDKVISELESENLMQL 849
            D +       Q +  IL+   EEL+ +      +   L E +K     + E++  N   +
Sbjct: 1446 DDIRKIKEETQNKRQILEKMAEELKKER----KDVAHLAEDTKREKNSLDEMKVANESSM 1501

Query: 850  IEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKS 909
             + +     + + K +I K               +I+KE+  I    D++E L++ + K 
Sbjct: 1502 ADLQKEKSNLEEMKENISK------------QTEDIEKEKDKIRLREDELEQLQAEIHKQ 1549

Query: 910  QEENQ----QLLVENSVLLGSLQQHQS-------EGEKLKLEKKTVEQEFENMREQNVIL 958
            Q E +     +  E + ++  ++  QS       + E LKL+++  E E E +++    L
Sbjct: 1550 QSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTEL 1609

Query: 959  QK-----DKVELLEENRQLRIEVVNGVEKENRSKSTLAALQAEMIELRQTNQVFQEENGK 1013
            ++     +K++L  ++ + R+E +     E  +      L    + + +  Q  +++   
Sbjct: 1610 EREADEIEKIKLETQHERQRVEEMTADFMETMNNER-KQLDKNKVMIEEQKQEMEKKRDD 1668

Query: 1014 MLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVLALSNLNLVYEIFFTENMVEKRALCEH 1073
            M   + SL  ++  +K  K   E+E +        L  + +  E    E    K      
Sbjct: 1669 MDQSRKSLDEDLKMMKAQKQVLEEEKN-------KLEQMKIGLEREADEISKIKEETQNE 1721

Query: 1074 LGNLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIERMDKELLEMDKRLKAAETSNAEF 1133
              NL  + N L +E   L +  E+K  +N  L++     +  L ++ K  +  E      
Sbjct: 1722 RQNLEKMANALKEEREYLAE--EIKR-KNQVLDKIKVANESTLADLQKEKRILEEMRENI 1778

Query: 1134 SRHIEELKMEQEESTKIKEN----LDRQILEQSENCMNHKKEIE---------------H 1174
            S+ IE+++ E+E+S K++E+    L  ++ +Q       K  IE                
Sbjct: 1779 SKQIEDIENEKEKS-KLREDELKKLQTEVQKQQSEIDMEKTNIESERAAMIREKQNMMTE 1837

Query: 1175 LNEANETLQFEMKTLLHEVE-QHRVRE------EALNLELLNKENEFKLWENEAAAFYHD 1227
            L + +E ++ +MK +L E E  H  R       E L  +L++ E + +  + +  AF ++
Sbjct: 1838 LKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSIERDSESLKLDKEAFENE 1897

Query: 1228 LQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMREIISLLESEIGGLKEQLSAY 1287
                       +  + ++    +I  DE     LE  H R+ +    ++I   +E+++  
Sbjct: 1898 -----------KEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINT- 1945

Query: 1288 VPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVIETCL------RKHSHQSARENE 1341
              LV  +K+  + ++       K    + +  ++   +E C       +K   +  R  E
Sbjct: 1946 --LVEEIKKKRDIIDESYTEIRKEKEAIESDRKEREDLENCWVEIEGEKKRMEEETRRLE 2003

Query: 1342 I--VLIPDGVSDLLTLQTRIRAVEKIM---MEELKRRVKQKSLTTESTPYSS--LEIATY 1394
            +    I    S+L   +  I + E+ +   MEEL +   +   T E     S  L+ AT 
Sbjct: 2004 MHREEIKKVDSELQKSRENIESREEKINNKMEELLQMKVEMGRTKEEIEKESQRLQDATI 2063

Query: 1395 PKVENRKKEIELVE---ENVFDRNSWRKKPKIRLLMKDIPLDRNVDDQNSKYLKRE-HRR 1450
              +EN K EI+  E   E++ D     K+ +I++ +          D+ +K L  E   +
Sbjct: 2064 -DLENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQL----------DKETKRLSEEIELK 2112

Query: 1451 TNDHVLELCENNEHEPLSAPTVDHAMICHRSDDSGRYLNYSSELDIE-KELGVDKLELSK 1509
              D  +E+ +    +                D  G       EL  E KEL    ++L++
Sbjct: 2113 VKDLEMEMADMKRQKQ------------EIEDTKGLLEKEKQELKQEKKELEDQMMDLTR 2160

Query: 1510 SVKEKTEDDKRRILERLSSDGQKLAILKMALQDLKKKTETKKKSKQGNDIEYETVKRHIE 1569
              K++TE+++  ++            LK  L+DL+K+ E  K+       +    K +IE
Sbjct: 2161 E-KQETEEERNNLM-----------ALKNQLEDLRKENEIVKE-------KLTLEKSNIE 2201

Query: 1570 EVEEAVMQQVSINDQMAKNVEEGASSLDREIPRRGSEQIGKLQFEVQNIQYILLKLAEEN 1629
            E++  + +Q  +NDQ  +  ++   SL+++  R  +EQ      + Q ++    K+ EE 
Sbjct: 2202 EMQLKIFKQQRLNDQTREENKKEKESLEQQ--RFETEQ------QKQMLEISTTKMMEEK 2253

Query: 1630 N 1630
            N
Sbjct: 2254 N 2254



 Score =  196 bits (499), Expect = 4e-48
 Identities = 349/1718 (20%), Positives = 733/1718 (42%), Gaps = 200/1718 (11%)

Query: 39   KVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHAMGELRHAHK 98
            K++ M   +E EAD  ++  E    KR  L K+ EE  R   +LA    H   + +   K
Sbjct: 1184 KLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIREKESLA----HLAEDTKTEKK 1239

Query: 99   TMPEAFPNSAYYILNDDSPCG-----SLGPDAESHTSARPTHRSKKNERSS--EESNGEV 151
             + E        + N+ S        S+  +   + S    +   + E+S   E+   ++
Sbjct: 1240 ILDEM------KVANESSMADLQREKSILEEMRENISKLKEYIDNEKEKSKLREDELKKL 1293

Query: 152  QT-LREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDDRASEAEIQVEIL 210
            QT +++   KM  +      + +   E +++ + +L++ +   + L     E E + EI+
Sbjct: 1294 QTEVQKQQKKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQ---ELEKEKEII 1350

Query: 211  KESLMQL---KADKDAGEVLYNQCLETIARLESMLSQKDNIEAKNLKQELTRVVVQKDTV 267
             ++  QL   +++ D  +   N  +ET+      L  KD  E +  KQE+ +   ++D +
Sbjct: 1351 MKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLD-KDKEEMEEQKQEMEK---ERDNM 1406

Query: 268  LLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEERDSLSVLY 327
                K   E + M++ +  + EE      +++E+ ++E+E    ++ ++ EE  +   + 
Sbjct: 1407 DQSRKSLDEDLKMMKLQKQVIEEEK----NKLEQMKIELEREADDIRKIKEETQNKRQIL 1462

Query: 328  HHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEIS----EKHRGMLEKSNQNLQLEA 383
                E++ K   ++ H+ E+ ++ KN +++     E S    +K +  LE+  +N+  + 
Sbjct: 1463 EKMAEELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQT 1522

Query: 384  ENLVQ---RIASKDHELLEKHTEIERLQTLMHGEHSNFIQIESAL----QALQKLYSQSQ 436
            E++ +   +I  ++ EL +   EI + Q+    E SN  +  +A+    + LQ       
Sbjct: 1523 EDIEKEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLD 1582

Query: 437  KEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVE-ENKTLHE--------LNFSSTRS 487
            ++  +L L+ +      ++L+  K + + E   I + + +T HE         +F  T +
Sbjct: 1583 RDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMN 1642

Query: 488  LKKQQMEISK--LKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQ 545
             +++Q++ +K  ++E K+++E++     +    L  +   +K   Q L E    + +   
Sbjct: 1643 NERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKI 1702

Query: 546  SLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDMNEVLME-NACMEFSLL 604
             L    +  +    + QNE   L++       E+E L E+ K  N+VL +     E +L 
Sbjct: 1703 GLEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLA 1762

Query: 605  GLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTL----LSQLQIITESMQKILENNT 660
             L  E   L    + I +  + ++ EK     EKS L    L +LQ   +  Q  ++   
Sbjct: 1763 DLQKEKRILEEMRENISKQIEDIENEK-----EKSKLREDELKKLQTEVQKQQSEIDMEK 1817

Query: 661  VLEKSLSDAKIE-----FEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVEEKL 715
               +S   A I         L+ KS D+E   K +  EK  L N+R++L   +E +++KL
Sbjct: 1818 TNIESERAAMIREKQNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKL 1877

Query: 716  SNLEKKVTNLEEKYADVEKDKESAVNQVEELFASI----LVQKENHSNHKHSSE--ARLA 769
             ++E+   +L+      E +KE+      +L         ++ E H   +   E  A++ 
Sbjct: 1878 MSIERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQ 1937

Query: 770  NLENIVRVLQEEQRLGK-------VEFEQELDRVVNAQIEMFILQNCIEELELKNFVLLT 822
                 +  L EE +  +        E  +E + + + + E   L+NC  E+E +   +  
Sbjct: 1938 KEREEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRKEREDLENCWVEIEGEKKRMEE 1997

Query: 823  ECEKLVEASKFSDKVISELES--ENLMQLIE------EEFLLHRIR--KFKMDIHKVCGV 872
            E  +L    +   KV SEL+   EN+    E      EE L  ++   + K +I K    
Sbjct: 1998 ETRRLEMHREEIKKVDSELQKSRENIESREEKINNKMEELLQMKVEMGRTKEEIEKESQR 2057

Query: 873  LQ---IDSDGGGDNEIKKEEIPISRILD-KIESLESSL-VKSQEENQQLLVENSVLLGSL 927
            LQ   ID +     EI+++E     I+D KI+  E  + ++  +E ++L  E  + +  L
Sbjct: 2058 LQDATIDLENA-KAEIQRQEDKFEDIIDIKIQEKEREIKIQLDKETKRLSEEIELKVKDL 2116

Query: 928  QQHQSEGEK-----------LKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRI-- 974
            +   ++ ++           L+ EK+ ++QE + + +Q + L ++K E  EE   L    
Sbjct: 2117 EMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQETEEERNNLMALK 2176

Query: 975  EVVNGVEKENR--------SKSTLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVS 1026
              +  + KEN          KS +  +Q ++ + ++ N   +EEN K   EK SL +   
Sbjct: 2177 NQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENKK---EKESLEQQRF 2233

Query: 1027 DLKDAKSSAEDENSVMFHDVLALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQ 1086
            + +  K   E   + M  +   +++L+   E+   ++ +EK A        +   +++ Q
Sbjct: 2234 ETEQQKQMLEISTTKMMEEKNEMADLSR--ELQKAKDELEKIAY-----KTNKERHEVEQ 2286

Query: 1087 EFGVLRKNFEVKEAENVYLNESIERMDKELLEMDKRLKAAETSNAEFSRHIEELKMEQEE 1146
                L    +  E +   + +    ++++ L + ++ +  +  N EF    E L    EE
Sbjct: 2287 MQAELHSQIQAIEQQGQIMQDKQNHLEEKELSIQRKEEEIKIGNTEFQIEQEHLNNVLEE 2346

Query: 1147 STKIKENLDRQILEQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLE 1206
            + K + +L+    +   N   + K+ E L +    L+ E   L    EQ +   E    E
Sbjct: 2347 TNKRQHDLEVMRADIELNKQKNNKDFELLEKIRSELENEKYDLQIWTEQQKHLVEVQLQE 2406

Query: 1207 LLNKENEFKLWENEAAAFYHDLQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHM 1266
            L  ++   +  E E  +     +      A L    +E+    +++D +   + + N  M
Sbjct: 2407 LEKEKERLEKMEIELQSKREQTEKEK---ADLNRVNAEIQREKQVIDKK---RHMTNRAM 2460

Query: 1267 REIISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVIE 1326
             E    LE+    LKE+          ++ +   LE   LL               V IE
Sbjct: 2461 EE----LETIKTELKER-------QEKIQTEQEKLEEEKLL---------------VQIE 2494

Query: 1327 T-CLRKHSHQSARENEIVLIPDGVSDLLTLQTRIRAVEKIMMEELKRRVKQKSLTTESTP 1385
               L K   +  R+ E + I +    ++    +IR +E+ +  E +  +K+         
Sbjct: 2495 AENLNKVLEEIKRQQEKLEISEADLKVMKEHEQIRNMEEAVKNE-RETLKE--------- 2544

Query: 1386 YSSLEIATYPKVENRKKEIE-LVEENVFDRNSWRK------KPKIRLLMKDIPLDRNVDD 1438
                   T   ++  KKEI+ ++EE    +    K        K  L  K   L++  ++
Sbjct: 2545 -------TEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREE 2597

Query: 1439 QNSKYLKREHRRTNDHVLELCENNEHEPLSAPTVDHAMICHRSDDSGRYLNYSSELDIEK 1498
             N K+ + + +R ++   ++ +  E +  +   ++    C   + +G+ +   ++ ++E 
Sbjct: 2598 INHKWTQFQ-QRIDEFDAQVRKQKEEDLTNQKKMEEERKC-LEEVNGKIIEMKTKAELEH 2655

Query: 1499 ELGVDKLELSKSVKEKTEDDKRR---ILERLSSDGQKLAILKMALQDLKKKTETKKKSKQ 1555
                 K+E  ++++E+   +K +   +  +L  + + L  +K  L  +++KTE   + K+
Sbjct: 2656 HEINQKIEELQTLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSEL--VREKTEVDHEQKK 2713

Query: 1556 GNDIEYETVKRHIEEVEEAVMQQVSINDQMAKNVEE-----GASSLDREIPRRGSEQIGK 1610
             ND + + +++  E++E+   + ++   +M K   E       + L++    +  E + K
Sbjct: 2714 LND-DIKMIEQEKEDLEKMKSEIMTQKQEMEKERSELDNKIQQTDLEKHDIEKSKEIVEK 2772

Query: 1611 LQFEVQNIQYILLKLAEENNNKVKNRISRKTGILLRRK 1648
            L FEV+  Q   ++L +E  +  + +I+ +  +L++ K
Sbjct: 2773 LMFEVEE-QRHEIQLQKEELDIERQKIADEQDLLIQNK 2809



 Score =  157 bits (397), Expect = 3e-36
 Identities = 262/1296 (20%), Positives = 529/1296 (40%), Gaps = 176/1296 (13%)

Query: 33   LTDIDTKVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHAMGE 92
            L +   K++ M   +E EAD  ++  E    +R  L K+         AL E  ++   E
Sbjct: 1690 LEEEKNKLEQMKIGLEREADEISKIKEETQNERQNLEKMAN-------ALKEEREYLAEE 1742

Query: 93   LRHAHKTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKNERSSEESNGEVQ 152
            ++  ++ + +    +   + +       L    E+ +       ++K +    E   E++
Sbjct: 1743 IKRKNQVLDKIKVANESTLADLQKEKRILEEMRENISKQIEDIENEKEKSKLRED--ELK 1800

Query: 153  TLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDDRASEAEIQV----- 207
             L+  + K QS+ D       E     S+    + + QN    L  ++ + E+Q+     
Sbjct: 1801 KLQTEVQKQQSEID------MEKTNIESERAAMIREKQNMMTELKKKSEDVEMQMKEILT 1854

Query: 208  --EILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIEAKN--LKQELTRVVVQ 263
              E+L      LK D    E L  + +      ES+   K+  E +   +KQ  T + +Q
Sbjct: 1855 EKELLHNDRNLLKKDV---EDLQQKLMSIERDSESLKLDKEAFENEKEAMKQMKTDLQIQ 1911

Query: 264  KDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEERDSL 323
             D +     +   +   +E K A  ++    +N  +E  + + + + ++  E+ +E++++
Sbjct: 1912 ADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEIKKKRDIIDESYTEIRKEKEAI 1971

Query: 324  SVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQLEA 383
                    E   K   ++ +     E  K ++E+E  +LE+   HR  ++K +  LQ   
Sbjct: 1972 --------ESDRKEREDLENCWVEIEGEKKRMEEETRRLEM---HREEIKKVDSELQKSR 2020

Query: 384  ENLVQR---IASKDHELLEKHTEIERLQTLMHGEHSNF----IQIESALQALQK------ 430
            EN+  R   I +K  ELL+   E+ R +  +  E        I +E+A   +Q+      
Sbjct: 2021 ENIESREEKINNKMEELLQMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFE 2080

Query: 431  -------------LYSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTL 477
                         +  Q  KE + L+ E++   L +KDLE+   D K + Q I E+ K L
Sbjct: 2081 DIIDIKIQEKEREIKIQLDKETKRLSEEIE---LKVKDLEMEMADMKRQKQEI-EDTKGL 2136

Query: 478  HELNFSSTRSLKKQQMEISKLKEIKEKLEREFHTSTEESNVLQRETHQI---KDDIQHLN 534
                      L+K++ E   LK+ K++LE +    T E    + E + +   K+ ++ L 
Sbjct: 2137 ----------LEKEKQE---LKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLR 2183

Query: 535  ERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALR---EKSKDMNE 591
            +  + + E+L     N       +   Q  N   +E  KKE    E  R   E+ K M E
Sbjct: 2184 KENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENKKEKESLEQQRFETEQQKQMLE 2243

Query: 592  V----LMEN----ACMEFSLLGLNDELDG------------------LRGTVKEIQQFCQ 625
            +    +ME     A +   L    DEL+                   L   ++ I+Q  Q
Sbjct: 2244 ISTTKMMEEKNEMADLSRELQKAKDELEKIAYKTNKERHEVEQMQAELHSQIQAIEQQGQ 2303

Query: 626  VLQEEKSILADEKSTLL----------SQLQIITESMQKILENNTVLEKSLSDAKIEFEG 675
            ++Q++++ L +++ ++           ++ QI  E +  +LE     +  L   + + E 
Sbjct: 2304 IMQDKQNHLEEKELSIQRKEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIEL 2363

Query: 676  LRIKSGD----LEDCCKLLNDEKNNLQ----NERSMLISQLEIVEEKLSNLEKKVTNLEE 727
             + K+      LE     L +EK +LQ     ++ ++  QL+ +E++   LEK    L+ 
Sbjct: 2364 NKQKNNKDFELLEKIRSELENEKYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQS 2423

Query: 728  KYADVEKDKESAVNQVEELFASILVQKENHSNHKHSSEARLANLENIVRVLQEEQRLGKV 787
            K    EK+K   +N+V    A I  +K+     +H +   +  LE I   L+E Q   + 
Sbjct: 2424 KREQTEKEKAD-LNRVN---AEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQT 2479

Query: 788  EFEQELDRVVNAQIEMFILQNCIEEL------------ELKNFVLLTECEKLVEASKFSD 835
            E E+  +  +  QIE   L   +EE+            +LK      +   + EA K   
Sbjct: 2480 EQEKLEEEKLLVQIEAENLNKVLEEIKRQQEKLEISEADLKVMKEHEQIRNMEEAVKNER 2539

Query: 836  KVISELESENLMQLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDN----EIKKEEI- 890
            + + E E+       E + ++    + K D+ K+   + +      +     E ++EEI 
Sbjct: 2540 ETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEIN 2599

Query: 891  -PISRILDKIESLESSLVKSQEE---NQQLLVENSVLLGSLQQHQSEGE-KLKLEKKTVE 945
               ++   +I+  ++ + K +EE   NQ+ + E    L  +     E + K +LE   + 
Sbjct: 2600 HKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEIN 2659

Query: 946  QEFENMR--EQNVILQKDKVELLEENRQLRIEVVNGVEKENRSKSTLAALQAEMIELRQT 1003
            Q+ E ++  ++ ++ +K+K E +    ++  E ++ ++ E         L  E  E+   
Sbjct: 2660 QKIEELQTLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSE---------LVREKTEVDHE 2710

Query: 1004 NQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVLALSNLNLVYEIFFTEN 1063
             +   ++   +  EK  L +  S++   K   E E S + + +         ++I  ++ 
Sbjct: 2711 QKKLNDDIKMIEQEKEDLEKMKSEIMTQKQEMEKERSELDNKIQQTDLEK--HDIEKSKE 2768

Query: 1064 MVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIERMDKELLEMDKRL 1123
            +VEK  L   +    H      +E  + R+    ++   +     ++  ++ +  +++ +
Sbjct: 2769 IVEK--LMFEVEEQRHEIQLQKEELDIERQKIADEQDLLIQNKSELQNENERIRNINEVI 2826

Query: 1124 KAAETSNAEFSRHIE----ELKMEQEESTKIKENLDRQILEQSENCMNHKKEIEHLNEAN 1179
            K    +  E   H+E    E+K   EE+ + KE+L++   +  E   +  K+ + L +  
Sbjct: 2827 KKERETLKEMEAHLEKEKEEMKSITEETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEK 2886

Query: 1180 ETLQFEMKTLLHEVEQHRVREEALNLELLNKENEFK 1215
            E +  E   L   +++   +      E L K+ E K
Sbjct: 2887 EDINHEWTQLQQRIDEFDAQVSKQKEEDLTKQKEMK 2922



 Score =  136 bits (342), Expect = 6e-30
 Identities = 233/1113 (20%), Positives = 468/1113 (41%), Gaps = 176/1113 (15%)

Query: 24   KNSKWLLENL-TDIDTKVKSMIKLIEE---EADSFARRAEMYYKKRPELMKLVEEFYRAY 79
            +N K  ++ + TD+  +   + K+  E   E      +     K+R E+  LVEE  +  
Sbjct: 1895 ENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEIKKKR 1954

Query: 80   RALAERYDHAMGELRHAHKTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKK 139
              + E Y     E         E           +D     +  + E       T R + 
Sbjct: 1955 DIIDESYTEIRKEKEAIESDRKE----------REDLENCWVEIEGEKKRMEEETRRLEM 2004

Query: 140  NERSSEESNGEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDDR 199
            +    ++ + E+Q  RE +   +        +    +E L +M+ ++ + +        R
Sbjct: 2005 HREEIKKVDSELQKSRENIESREE-------KINNKMEELLQMKVEMGRTKEEIEKESQR 2057

Query: 200  ASEAEIQVEILK----------ESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIE 249
              +A I +E  K          E ++ +K  +   E+      ET       LS++  ++
Sbjct: 2058 LQDATIDLENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQLDKET-----KRLSEEIELK 2112

Query: 250  AKNLKQELTRVVVQKDTV-------------LLQYKQCLEK--IPMLENKIALAEENSRM 294
             K+L+ E+  +  QK  +             L Q K+ LE   + +   K    EE + +
Sbjct: 2113 VKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQETEEERNNL 2172

Query: 295  --LNDQIE--RTELEVETLRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHVQENAEQ 350
              L +Q+E  R E E+   +  L + N E   L +     L   ++ EN+    +E+ EQ
Sbjct: 2173 MALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENK--KEKESLEQ 2230

Query: 351  LKNKIEKEAEKLEISEKHRGMLEKSNQNLQL-----EAENLVQRIASKDHELLEKHTEIE 405
             + + E++ + LEIS     M+E+ N+   L     +A++ +++IA K ++  E+H E+E
Sbjct: 2231 QRFETEQQKQMLEISTTK--MMEEKNEMADLSRELQKAKDELEKIAYKTNK--ERH-EVE 2285

Query: 406  RLQTLMHGEHSNFIQIESALQALQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQDFKE 465
            ++Q  +H   S    IE   Q +Q    Q+  E++ L+++ K   + + + E   +  +E
Sbjct: 2286 QMQAELH---SQIQAIEQQGQIMQD--KQNHLEEKELSIQRKEEEIKIGNTEFQIE--QE 2338

Query: 466  EMQGIVEE-NKTLHELNFSSTRSLKKQQMEISKLKEIK--EKLEREFHTSTEESNVLQRE 522
             +  ++EE NK  H+L       + +  +E++K K  K  E LE+           ++ E
Sbjct: 2339 HLNNVLEETNKRQHDLE------VMRADIELNKQKNNKDFELLEK-----------IRSE 2381

Query: 523  THQIKDDIQHLNERYQAMLE-QLQSLGLNPNSFAASVRDLQNENFML-KETCKKEHSEKE 580
                K D+Q   E+ + ++E QLQ L            +LQ++     KE         E
Sbjct: 2382 LENEKYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKREQTEKEKADLNRVNAE 2441

Query: 581  ALREKSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKST 640
              REK     +  M N  ME        EL+ ++  +KE Q+  Q  QE+   L +EK  
Sbjct: 2442 IQREKQVIDKKRHMTNRAME--------ELETIKTELKERQEKIQTEQEK---LEEEKLL 2490

Query: 641  LLSQLQIITESMQKILENNTVLEKSLSDAKI--EFEGLRIKSGDLEDCCKLLNDEKNNLQ 698
            +  + + + + +++I      LE S +D K+  E E +R     +++  + L + + +LQ
Sbjct: 2491 VQIEAENLNKVLEEIKRQQEKLEISEADLKVMKEHEQIRNMEEAVKNERETLKETEAHLQ 2550

Query: 699  NERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHS 758
             ++  + S +E    +  +LEK  T +  +  +++  K++   + EE+            
Sbjct: 2551 RDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEI------------ 2598

Query: 759  NHKHSS-EARLANLENIVRVLQEEQRLGKVEFEQE-----------LDRVVNAQIEMFIL 806
            NHK +  + R+   +  VR  +EE    + + E+E           ++    A++E   +
Sbjct: 2599 NHKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEI 2658

Query: 807  QNCIEELELKNFVLLTECEKLVEASKFS--------DKVISELESENLMQLIEEEFL--- 855
               IEEL+     ++ E EK  EA            D++ SEL  E      E++ L   
Sbjct: 2659 NQKIEELQTLQEQIMKEKEK-AEAMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDD 2717

Query: 856  LHRIRKFKMDIHKVCGVL----------------QIDSDGGGDNEIKKEEIPISRILDKI 899
            +  I + K D+ K+   +                +I       ++I+K +  + +++ ++
Sbjct: 2718 IKMIEQEKEDLEKMKSEIMTQKQEMEKERSELDNKIQQTDLEKHDIEKSKEIVEKLMFEV 2777

Query: 900  ESLESSLVKSQEE----NQQLLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQN 955
            E     +   +EE     Q++  E  +L+ +  + Q+E E+++   + +++E E ++E  
Sbjct: 2778 EEQRHEIQLQKEELDIERQKIADEQDLLIQNKSELQNENERIRNINEVIKKERETLKEME 2837

Query: 956  VILQKDKVE---LLEENRQLRIE---VVNGVEKENR---SKSTLAALQAEMI--ELRQTN 1004
              L+K+K E   + EE R+ + +   +   ++++N+    +  L   + E I  E  Q  
Sbjct: 2838 AHLEKEKEEMKSITEETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKEDINHEWTQLQ 2897

Query: 1005 QVFQEENGKMLDEKNSLCRNVSDLKDAKSSAED 1037
            Q   E + ++  +K        ++K+ + S E+
Sbjct: 2898 QRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEE 2930



 Score =  108 bits (270), Expect = 1e-21
 Identities = 191/988 (19%), Positives = 411/988 (41%), Gaps = 137/988 (13%)

Query: 706  SQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHS----NHK 761
            S  +++E++  NLEK  + L +   D+EK KE+ + ++++    +    EN +      K
Sbjct: 2    SDKDMLEKEKHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITIEMHEIK 61

Query: 762  HSSEARLANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQNCIEELELKNFVLL 821
            H  E      + + ++  E Q L + E E+E + ++  + E+ + Q+   EL+ +   + 
Sbjct: 62   HQEEQMKQKQDELDQLKTEIQNL-QQELEKEKEIIMKDRSELDLRQS---ELDKQQTNMN 117

Query: 822  TECEKLVEASKFSDKVISELESENLMQLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGG 881
               E +    K  DK   E+E +      E + +   I+    D+               
Sbjct: 118  DIIETMKNERKLLDKDKEEMEEQKQEMEKERDNMDQSIKSLDEDL--------------- 162

Query: 882  DNEIKKEEIPISRILDKIESLESSL---VKSQEENQQLLVENSVLLG----SLQQHQSEG 934
               +K ++  I    +K+E ++ SL   +K  +  +Q++ E    L      L++   E 
Sbjct: 163  -KMMKLQKQVIEEEKNKLEQMKKSLDEDLKMMKLQKQVIEEEKSKLKQMKIELEREADEI 221

Query: 935  EKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKEN--------RS 986
             K+K E +   Q FE M E    L+K++ +L E+ ++ + +V++ ++  N        R 
Sbjct: 222  RKVKEETQNERQIFEKMTE---ALKKEREDLSEDAKR-KNQVLDEMKVANESTLADILRE 277

Query: 987  KSTLAAL------QAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENS 1040
            +S L  +      Q E +E ++     +EE  K L  +  + +  S+ +  KS+ E E +
Sbjct: 278  RSNLQEMRENISKQTEDVENKKEKIRLREEKLKQLQAE--IHKQQSETEKEKSNIERERA 335

Query: 1041 VMFHDVLALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEA 1100
             +  DV  L +  +  +       +++ A       L  +  +L +E   + K     + 
Sbjct: 336  AIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIEK----IKL 391

Query: 1101 ENVYLNESIERMDKELLE-MDKRLKAAETSNAEFSRHIEELKMEQEESTKIKENLD---- 1155
            E  +  + +E M  + +E M+   K    +  E     +E++ E+ +  + +++LD    
Sbjct: 392  ETQHERQRVEEMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLK 451

Query: 1156 -----RQILEQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLELLNK 1210
                 +Q++E+ +N +   K IE   EA+     E++ +  E +  R R E +  EL  +
Sbjct: 452  MMKLQKQVIEEEKNKLEQMK-IELEKEAD-----EIRKIKEETQNERQRLEKMTEELKKE 505

Query: 1211 ENEFKLWENEAAAFYHDLQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMREII 1270
            +  F     +       L    +    L + + +     + + +  S ++ ++E  +E I
Sbjct: 506  KESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKI 565

Query: 1271 SLLESEIGGLKEQLSAYVPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVIETCLR 1330
             L E E+    EQL A +     +KE   ++E                + +D++ +    
Sbjct: 566  RLREDEL----EQLQAEIHKQQEIKEKIKAIE----------------SDRDMLEK---E 602

Query: 1331 KHSHQSARENEIVLIPDGVSDLLTLQTRIRAVEKIMMEELKRRVKQKSLTTESTPYSSLE 1390
            KH  +  R           S LL  +  +    KI + E+++  +      E       +
Sbjct: 603  KHDLEKTR-----------SKLLRAKENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHD 651

Query: 1391 IA-TYPKVENRKKEIELVEENVFDRNSWRKKPKIRLLMKDIPLDRNVDDQNSKYLKREHR 1449
            I     +++ ++ E++ ++  + +     +K K  ++MK    DR+  D     L ++  
Sbjct: 652  IKHQEEQMKQKQDELDQLKTEIQNLQQELEKEK-EIIMK----DRSQLDLRQSELDKQQT 706

Query: 1450 RTNDHVLELCEN------NEHEPLSAPTVDHAMICHRSDDSGRYLNYSSE-LDIEKELGV 1502
              ND ++E  +N       + E       +     H  D S + L+   + + ++K++  
Sbjct: 707  NVND-IMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLE 765

Query: 1503 D---KLELSKSVKEKTEDDKRRILERLSSDGQKLAILKMAL--------QDLKKKTETKK 1551
            D   KLE  K   E+   + R+I E + ++ Q L  +  AL        ++ KK  +   
Sbjct: 766  DEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVLD 825

Query: 1552 KSKQGNDIEYETV---KRHIEEVEEAVMQQVSINDQMAKNV---EEGASSLDREIPRRGS 1605
            + K  N+     +   K ++EE+ E + +Q    +   +N+   E+    L  EI ++  
Sbjct: 826  EMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDELRQLQAEIHKQ-Q 884

Query: 1606 EQIGKLQFEVQNIQYILLKLAEENNNKV 1633
             +I K +  +++ +  ++K  E+  +K+
Sbjct: 885  REIEKEKINIESERAAIIKDVEDLQHKI 912



 Score = 73.2 bits (178), Expect = 6e-11
 Identities = 103/508 (20%), Positives = 222/508 (43%), Gaps = 57/508 (11%)

Query: 30   LENLTDIDTKVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALA-ERYDH 88
            +E L  I T++K   + I+ E +       +   +   L K++EE  R    L     D 
Sbjct: 2460 MEELETIKTELKERQEKIQTEQEKLEEEKLLVQIEAENLNKVLEEIKRQQEKLEISEADL 2519

Query: 89   AMGELRHAHKTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKN-ERSSEES 147
             + +     + M EA  N    +   ++         E  +    T R K++ E+ S   
Sbjct: 2520 KVMKEHEQIRNMEEAVKNERETLKETEAHLQR--DKKEIKSIIEETSRQKEDLEKISTGM 2577

Query: 148  NGEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQ-----NNARGLDDRASE 202
            N + Q L+     ++ +++ +  ++ +  + + + +  + K +     N  +  ++R   
Sbjct: 2578 NVQKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCL 2637

Query: 203  AEIQVEILKESLMQLKADKDAGEVLYNQCLETIARL-ESMLSQKDNIEAKNLKQELTRVV 261
             E+  +I++   M+ KA+ +  E+  NQ +E +  L E ++ +K+  EA  +K ++ R  
Sbjct: 2638 EEVNGKIIE---MKTKAELEHHEI--NQKIEELQTLQEQIMKEKEKAEAMTIKLKMER-- 2690

Query: 262  VQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEERD 321
              +D   ++ +   EK  +        +   + LND I+  E E E L K  +E+  ++ 
Sbjct: 2691 --EDLDQIKSELVREKTEV--------DHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQKQ 2740

Query: 322  SLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQL 381
             +        ++ S+++N+I    +  +  K+ IEK  E   I EK    +E+    +QL
Sbjct: 2741 EME-------KERSELDNKI----QQTDLEKHDIEKSKE---IVEKLMFEVEEQRHEIQL 2786

Query: 382  EAENLV---QRIASKDHELLEKHTEIERLQTLMHGEHSNFIQIESALQALQKLYSQSQKE 438
            + E L    Q+IA +   L++  +E++     +   +    +    L+ ++    + ++E
Sbjct: 2787 QKEELDIERQKIADEQDLLIQNKSELQNENERIRNINEVIKKERETLKEMEAHLEKEKEE 2846

Query: 439  QRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTL----HELNFSST---RSLKKQ 491
             +++  E +      +DLE    D KE+ Q ++++   L     ++N   T   + + + 
Sbjct: 2847 MKSITEETRRQK---EDLEKMSTDIKEQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEF 2903

Query: 492  QMEISKLKE---IKEKLEREFHTSTEES 516
              ++SK KE    K+K  +E   S EE+
Sbjct: 2904 DAQVSKQKEEDLTKQKEMKEERKSLEET 2931


>UniRef100_UPI0000437336 UPI0000437336 UniRef100 entry
          Length = 1949

 Score =  216 bits (551), Expect = 4e-54
 Identities = 327/1674 (19%), Positives = 701/1674 (41%), Gaps = 261/1674 (15%)

Query: 47   IEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHAMGEL---RHAHKTMPEA 103
            IEE+  S     +M  K++ +L K   E Y+    L ++ ++ + E+   R   + M E 
Sbjct: 6    IEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNEN 65

Query: 104  FPNSAYYILNDDSPCG--------------SLGPDAESHTSARPTHRSKKNERSSEESNG 149
                 + I + +                  +L  + E         RS+ + R SE    
Sbjct: 66   ITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQ 125

Query: 150  EVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDDRASEAEIQVEI 209
            +   + + +  M++++  L    +E  E   +ME + +    + + LD+   + ++Q ++
Sbjct: 126  QTN-MNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQM 184

Query: 210  LKE-----SLMQLKADKDAGEV--LYNQCLETIARLESM----LSQKDNIEAK--NLKQE 256
             +E       M+++ +++A E+  +  +      RLE M    + +K+ ++ K  +++ +
Sbjct: 185  FEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIREKEKLKKKSEDVEIQ 244

Query: 257  LTRVVVQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEM 316
            +  ++ +K+ +    K     +  L+ K+   E +S+ L    E  E E E +++   ++
Sbjct: 245  MKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDL 304

Query: 317  NEERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSN 376
              + D           +I K++ E  H ++  E++  +I+KE +K+        ++E++N
Sbjct: 305  QIQAD-----------EIEKIKLETQHDRQRVEEMAAQIQKERDKI------NNLIEETN 347

Query: 377  QNLQLEAENLVQRIASKDHELLEKHTEIERLQTLMHGEHSNFIQIESALQALQKLYSQSQ 436
            +   +        +  K+ ++ EK   I+  + ++  E  N   +E     L K+    +
Sbjct: 348  RKDMV--------LNEKNRDIEEKIKSIQSDKDMLEKERHN---LEKTRSELYKVKEDLE 396

Query: 437  KEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEE----NKTLHELNFSSTRSLKKQQ 492
            K++ N   E++      +D+E   ++   EM  I  +    N+   EL+   T  ++  Q
Sbjct: 397  KQKENTLAEIQKE---REDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKT-EIQNLQ 452

Query: 493  MEISKLKEIKEKLEREFHTSTEESNVLQRETHQI----KDDIQHLNERYQAMLEQLQSLG 548
             E+ K KEI  K   +F     E +  Q   + I    K++ + L++  + M EQ Q + 
Sbjct: 453  QELEKEKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEME 512

Query: 549  LNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDMNEVLMENACMEFSLLGLND 608
               + F  S + L  +  M+K   +K+  E+    EK+KD          +E  +  +  
Sbjct: 513  KEKHDFDQSRKSLDKDLKMMK--LQKQVFEE----EKNKD----------IEKKIKSIQS 556

Query: 609  ELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESMQKILENNTVLEKSLSD 668
            + D L     ++++    L + K  L  +K   L+Q+Q   E ++K+ EN T   + + +
Sbjct: 557  DKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENIT---REMHE 613

Query: 669  AKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEE- 727
             K + E +  K  +L+     + + +  L+ E+ +++     ++ + S L+K+ TN+ + 
Sbjct: 614  IKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDI 673

Query: 728  ------KYADVEKDKESAVNQVEELFASILVQKENHSNHKHSSEARLANLENIVRVLQEE 781
                  +   ++KDKE    Q +E+      +++N    + S +  L  ++   +V++EE
Sbjct: 674  METMKNERKQLDKDKEEMEEQKQEMEK----ERDNMDQSRKSLDEDLKMMKLQKQVIEEE 729

Query: 782  Q---RLGKVEFEQELDRV----VNAQIEMFILQNCIEELELKNFVLLTECEKLVEASKFS 834
            +      K+E E+E D +       Q +  IL+   EEL+ +      +   L E +K  
Sbjct: 730  KNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELKKER----KDVAHLAEDTKRE 785

Query: 835  DKVISELESENLMQLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPISR 894
               + E++  N   + + +     + + K +I K               +I+KE+  I  
Sbjct: 786  KNSLDEMKVANESSMADLQKEKSNLEEMKENISK------------QTEDIEKEKDKIRL 833

Query: 895  ILDKIESLESSLVKSQEENQ----QLLVENSVLLGSLQQHQS-------EGEKLKLEKKT 943
              D++E L++ + K Q E +     +  E + ++  ++  QS       + E LKL+++ 
Sbjct: 834  REDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREA 893

Query: 944  VEQEFENMREQNVILQK-----DKVELLEENRQLRIEVVNGVEKENRSKSTLAALQAEMI 998
             E E E +++    L++     +K++L  ++ + R+E +     E  +      L    +
Sbjct: 894  FENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNER-KQLDKNKV 952

Query: 999  ELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVLALSNLNLVYEI 1058
             + +  Q  +++   M   + SL  ++  +K  K   E+E + +                
Sbjct: 953  MIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKL---------------- 996

Query: 1059 FFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIERMDKELLE 1118
               E M  K  L      +S +  +   E   L K     + E  YL E I+R ++ L  
Sbjct: 997  ---EQM--KIGLEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVL-- 1049

Query: 1119 MDKRLKAAETSNAEFSRHIEELKMEQEESTKIKENLDRQILEQSENCMNHKKEIEHLNEA 1178
               ++K A  S       + +L+ E+    +++EN+ +QI           ++IE+  E 
Sbjct: 1050 --DKIKVANEST------LADLQKEKRILEEMRENISKQI-----------EDIENEKEK 1090

Query: 1179 NETLQFEMKTLLHEVEQHRVREEALNLELLNKENEFKLWENEAAAFYHDLQMSSICLALL 1238
            ++  + E+K L  EV++   ++  +++E  N E+E      E      +L+  S     +
Sbjct: 1091 SKLREDELKKLQTEVQK---QQSEIDMEKTNIESERAAMIREKQNMMTELKKKS---EDV 1144

Query: 1239 ESKVSELTGVCKILDDESSAKSLENEHMREIISLLESEIGGLKEQLSAYVPLVSSLKEDF 1298
            E ++ E+    ++L ++ +    + E +++ +  +E +   LK    A+     ++K+  
Sbjct: 1145 EMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSIERDSESLKLDKEAFENEKEAMKQMK 1204

Query: 1299 NSLEHISLLWTKRNSVVGNGAQKDVVIETCLRKHSHQSARENEIVLIPDGVSDLLTLQTR 1358
              L+                 Q D + +  L  H  +   E +   I     ++ TL   
Sbjct: 1205 TDLQ----------------IQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEE 1248

Query: 1359 IRAVEKIMMEELKRRVKQKSLTTESTPYSSLEIATYPKVENRKKEIELVEENVFDRNSWR 1418
            I+    I+ E      K+K      +  S LE A   +   + K IE+    +  + +  
Sbjct: 1249 IKKKRDIIDESYTEIRKEKEAI--ESDRSDLEKAK-SQTFKQNKNIEIALAEIQQKRNAL 1305

Query: 1419 KKPKIRLLMKDIPLDRNVDDQNSKYLKRE-HRRTNDHVLELCENNEHEPLSAPTVDHAMI 1477
            +K KI++ +          D+ +K L  E   +  D  +E+ +    +            
Sbjct: 1306 EKMKIKIQL----------DKETKRLSEEIELKVKDLEMEMADMKRQKQ----------- 1344

Query: 1478 CHRSDDSGRYLNYSSELDIE-KELGVDKLELSKSVKEKTEDDKRRILERLSSDGQKLAIL 1536
                D  G       EL  E KEL    ++L++  K++TE+++  ++            L
Sbjct: 1345 -EIEDTKGLLEKEKQELKQEKKELEDQMMDLTRE-KQETEEERNNLM-----------AL 1391

Query: 1537 KMALQDLKKKTETKKKSKQGNDIEYETVKRHIEEVEEAVMQQVSINDQMAKNVEEGASSL 1596
            K  L+DL+K+ E  K+       +    K +IEE++  + +Q  +NDQ  +  ++   SL
Sbjct: 1392 KNQLEDLRKENEIVKE-------KLTLEKSNIEEMQLKIFKQQRLNDQTREENKKEKESL 1444

Query: 1597 DRE--------IPRRGSEQIGKLQFEVQNI--QYILLKLAEENNNKVKNRISRK 1640
            +++        I     E+  K+Q E + +  + +L+++  EN NKV   I R+
Sbjct: 1445 EQQRAMEELETIKTELKERQEKIQTEQEKLEEEKLLVQIEAENLNKVLEEIKRQ 1498



 Score =  206 bits (523), Expect = 6e-51
 Identities = 320/1678 (19%), Positives = 690/1678 (41%), Gaps = 190/1678 (11%)

Query: 29   LLENLTDIDTKVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDH 88
            L+E     D  +    + IEE+  S     +M  K+R  L K   E Y+    L ++ ++
Sbjct: 342  LIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKEN 401

Query: 89   AMGELRHAHKTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKNERSSEESN 148
             + E++   + + +   N                   E H       +  + +   ++  
Sbjct: 402  TLAEIQKEREDVEKMNENIT----------------REMHEIKHQEEQMNQKQDELDQLK 445

Query: 149  GEVQTLREALAK----MQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDDRASEAE 204
             E+Q L++ L K    +  D+    L+  E  +  + M   +   +N  + LD    E E
Sbjct: 446  TEIQNLQQELEKEKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEME 505

Query: 205  IQVE--------------ILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIEA 250
             Q +               L + L  +K  K   E   N+ +E   +++S+ S KD +E 
Sbjct: 506  EQKQEMEKEKHDFDQSRKSLDKDLKMMKLQKQVFEEEKNKDIE--KKIKSIQSDKDMLEK 563

Query: 251  KNLKQELTR---------VVVQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIER 301
            +    E TR         +  QK+  L Q ++  E +  +   I       +   +Q+ +
Sbjct: 564  EKHDLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQ 623

Query: 302  TELEVETLRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEK 361
             + E++ L+  +  + +E +    +      ++ + ++E+   Q N   +   ++ E ++
Sbjct: 624  KQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQ 683

Query: 362  LEISEKHRGMLEKSNQNLQLEAENLVQRIASKDHELL----------EKHTEIERLQTLM 411
            L   +K +  +E+  Q ++ E +N+ Q   S D +L           E+  ++E+++  +
Sbjct: 684  L---DKDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIEL 740

Query: 412  HGEHSNFIQI----ESALQALQKLYSQSQKEQR---NLALELKYGLLLLKDLELSKQDFK 464
              E  +  +I    ++  Q L+K+  + +KE++   +LA + K     L +++++ +   
Sbjct: 741  EREADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAEDTKREKNSLDEMKVANESSM 800

Query: 465  EEMQGIVEENKTLHELNFSSTRSLKKQQMEISKLKEIKEKLEREFH-----TSTEESNVL 519
             ++Q      + + E     T  ++K++ +I   ++  E+L+ E H     T  E+SN+ 
Sbjct: 801  ADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQQSETEIEKSNI- 859

Query: 520  QRETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLK---ETCKKEH 576
            +RE   I  D++ L  +  ++    +SL L+  +F     +L+     L+   +  +K  
Sbjct: 860  ERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIK 919

Query: 577  SEKEALREKSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILAD 636
             E +  R++ ++M    ME    E   L  N  +  +    +E+++    + + +  L +
Sbjct: 920  LETQHERQRVEEMTADFMETMNNERKQLDKNKVM--IEEQKQEMEKKRDDMDQSRKSLDE 977

Query: 637  EKSTLLSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNN 696
            +   + +Q Q++ E   K+ +    LE+   +     E  + +  +LE     L +E+  
Sbjct: 978  DLKMMKAQKQVLEEEKNKLEQMKIGLEREADEISKIKEETQNERQNLEKMANALKEEREY 1037

Query: 697  LQNERSMLISQLEIVEEKLSNLEK-KVTNLEEKYADVEKDKESAVNQVEELFASILVQKE 755
            L  E          ++ K   L+K KV N E   AD++K+K      +EE+  +I  Q E
Sbjct: 1038 LAEE----------IKRKNQVLDKIKVAN-ESTLADLQKEKRI----LEEMRENISKQIE 1082

Query: 756  NHSNHKHSSEAR---LANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFI-LQNCIE 811
            +  N K  S+ R   L  L+  V+  Q E  + K   E E   ++  +  M   L+   E
Sbjct: 1083 DIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAAMIREKQNMMTELKKKSE 1142

Query: 812  ELELKNFVLLTECEKLVEASKFSDKVISELESENLMQLIEEEFLL----HRIRKFKMDIH 867
            ++E++   +LTE E L        K + +L+ + LM +  +   L          K  + 
Sbjct: 1143 DVEMQMKEILTEKELLHNDRNLLKKDVEDLQ-QKLMSIERDSESLKLDKEAFENEKEAMK 1201

Query: 868  KVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSVLLGSL 927
            ++   LQI +D     EI+K ++       ++E   + + K +EE   L+ E       +
Sbjct: 1202 QMKTDLQIQAD-----EIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEIKKKRDII 1256

Query: 928  QQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKENRSK 987
             +  +E   ++ EK+ +E +  +       L+K K +  ++N+ + I +    +K N  +
Sbjct: 1257 DESYTE---IRKEKEAIESDRSD-------LEKAKSQTFKQNKNIEIALAEIQQKRNALE 1306

Query: 988  STLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVL 1047
                 +Q +    ++T ++ +E   K+ D    L   ++D+K  K   ED   ++  +  
Sbjct: 1307 KMKIKIQLD----KETKRLSEEIELKVKD----LEMEMADMKRQKQEIEDTKGLLEKEKQ 1358

Query: 1048 ALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENVYLNE 1107
             L       E    +   EK+   E   NL  L N L      LRK  E+ + +      
Sbjct: 1359 ELKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLED----LRKENEIVKEKLTLEKS 1414

Query: 1108 SIERMDKELLEMDKRLKAAETSNAEFSRHIEELKMEQEESTKIKENLDRQILEQSENCMN 1167
            +IE M  ++ +  +        N +     E+  +EQ+ + +  E +  ++ E+ E    
Sbjct: 1415 NIEEMQLKIFKQQRLNDQTREENKK-----EKESLEQQRAMEELETIKTELKERQEKI-- 1467

Query: 1168 HKKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLELLNKENEFKLWENEAAAFYHD 1227
             + E E L E    +Q E + L   +E+ + ++E L +     E + K+           
Sbjct: 1468 -QTEQEKLEEEKLLVQIEAENLNKVLEEIKRQQEKLEI----SEADLKV----------- 1511

Query: 1228 LQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMREIISL---LESEIGGLKEQL 1284
              M   C    E    +   + + + +  +AK L  +  ++I      L+ +   L  ++
Sbjct: 1512 --MKEQCENAREETERKKCDIEEQIQNNENAKHLLEQERKDIDKQKQELQKQADDLDMRM 1569

Query: 1285 SAYVPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVIETCLRKHSHQSARENEIVL 1344
             A+   V   K   +  E   LL  K N ++      +   E  ++K +     +NE   
Sbjct: 1570 IAHRENVEMSKRSLD--EEKKLLEQKANEILRQRDDLEKEKEDMMKKWNKLDVLQNE--- 1624

Query: 1345 IPDGVSDLLTLQTRIRAVEKIMME------ELKRRVK--QKSLTTESTPYSSLEIATYPK 1396
                      +Q   +A+E+I  E      E+ +  +  ++SL   +     LEI    +
Sbjct: 1625 ----------MQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGDLEIM---R 1671

Query: 1397 VENRKKEIELVEENVFDRNSWRKKPKIRLLMKDIPLDRNVDDQNSKYLKREHRRTNDHVL 1456
             +  K+E ++ E  V  +   ++  +I+  +K++      + +  K +  E RR  + + 
Sbjct: 1672 ADYEKQEQQIEEMRVEAKMERKELDQIKKTLKEMEAYLEKEKEEMKSITEETRRQKEDLE 1731

Query: 1457 ELCENNEHEPLSAPTVDHAMICHRSDDSGRYLNYSSELDIEKELGVDKLELSKSVKEKTE 1516
            ++  +   +     +    +   R + + ++      +D E +  V K +     KEK  
Sbjct: 1732 KMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRID-EFDAQVSKQKEEDLPKEKEM 1790

Query: 1517 DDKRRILERLSSDGQKLAILKMALQDLKKKTETKKKSKQGNDIEYETVKRHIEEVEEAVM 1576
             + R+ LE   ++  ++   K   +++KK+ E K++ +Q   ++ E  ++ IE+++  + 
Sbjct: 1791 KEDRKSLEETKANILEMK-TKAEPEEIKKEKE-KEEEEQEMRVKVEMERKEIEQIKSQLE 1848

Query: 1577 QQVSINDQMAKNVEEGASSLDREIPRRGSEQIGKLQFEVQNIQYILLKLAEENNNKVK 1634
            +  S  D   K + +    +++E      E + K++ E+   +  + +   E + K+K
Sbjct: 1849 RVRSEMDHEQKKLNDDKKMIEQE-----KEDLEKMKSEIMKQRQQMEEERSELDKKIK 1901



 Score =  191 bits (485), Expect = 2e-46
 Identities = 331/1565 (21%), Positives = 661/1565 (42%), Gaps = 167/1565 (10%)

Query: 132  RPTHRSKKNERSSEESNGEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQN 191
            R   + KK     E    E+ T +E L    +D+  L       +ENL +   DL +   
Sbjct: 229  REKEKLKKKSEDVEIQMKEILTEKELL---HNDRKLL----TRDVENLQQKLIDLERDSK 281

Query: 192  NARGLDDRASEAEIQVEILKESLMQLKAD----KDAGEVLYNQCLETIARLESMLSQ--K 245
              + LD  A E E      KE++ Q+K D     D  E +  +      R+E M +Q  K
Sbjct: 282  RLK-LDREAFENE------KEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQK 334

Query: 246  DNIEAKNLKQELTRVVVQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELE 305
            +  +  NL +E  R    KD VL       EK   +E KI   + +  ML       E E
Sbjct: 335  ERDKINNLIEETNR----KDMVLN------EKNRDIEEKIKSIQSDKDML-------EKE 377

Query: 306  VETLRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEIS 365
               L K  +E+ + ++ L     + L +I K   ++  + EN  +  ++I+ + E++   
Sbjct: 378  RHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQK 437

Query: 366  EKHRGMLEKSNQNLQLEAENLVQRIASKDHELLEKHTEIERLQT----LMHGEHSNFIQI 421
            +     L+   QNLQ E E   + I     +   + +E+++ QT    +M    +   Q+
Sbjct: 438  QDELDQLKTEIQNLQQELEKEKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQL 497

Query: 422  ESALQALQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEEN----KTL 477
            +   + +++   + +KE+ +     K     LK ++L KQ F+EE    +E+     ++ 
Sbjct: 498  DKDKEEMEEQKQEMEKEKHDFDQSRKSLDKDLKMMKLQKQVFEEEKNKDIEKKIKSIQSD 557

Query: 478  HELNFSSTRSLKKQQMEISKLKEIKEK--------LEREFHTSTEESNVLQRETHQIKDD 529
             ++       L+K + E+ K+KE  EK        +++E     + +  + RE H+IK  
Sbjct: 558  KDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHEIKHQ 617

Query: 530  IQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDM 589
             + +N++ Q  L+QL++           +++LQ E    KE   K  S+ +  R+   D 
Sbjct: 618  EEQMNQK-QDELDQLKT----------EIQNLQQELEKEKEIIMKARSQLDR-RQSELDK 665

Query: 590  NEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIIT 649
             +  M N  ME     + +E   L    +E+++  Q +++E+  +   + +L   L+++ 
Sbjct: 666  QQTNM-NDIME----TMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMK 720

Query: 650  ESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLE 709
               Q I E    LE+   + + E + +R    + ++  ++L      L+ ER  +    E
Sbjct: 721  LQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAE 780

Query: 710  IVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHSNHKHSSEARLA 769
              + + ++L++     E   AD++K+K    + +EE+  +I  Q E+    K     R  
Sbjct: 781  DTKREKNSLDEMKVANESSMADLQKEK----SNLEEMKENISKQTEDIEKEKDKIRLRED 836

Query: 770  NLENI---VRVLQEEQRLGKVEFEQE----LDRVVNAQIEMFILQNCIEELELKNFVLLT 822
             LE +   +   Q E  + K   E+E    +  V + Q ++  L    E L+L       
Sbjct: 837  ELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFEN 896

Query: 823  ECEKL----VEASKFSDKVIS-ELESENLMQLIEE---EFL--LHRIRKFKMDIHKVCGV 872
            E E+L     E  + +D++   +LE+++  Q +EE   +F+  ++  RK ++D +KV   
Sbjct: 897  EKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERK-QLDKNKV--- 952

Query: 873  LQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSVLLGSLQQHQS 932
              +  +   + E K++++  SR     +SL+  L   + + Q L  E + L       + 
Sbjct: 953  --MIEEQKQEMEKKRDDMDQSR-----KSLDEDLKMMKAQKQVLEEEKNKLEQMKIGLER 1005

Query: 933  EGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKENRSKSTLAA 992
            E +++   K+  + E +N+ +    L++++  L EE ++ + +V++ ++  N  +STLA 
Sbjct: 1006 EADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKR-KNQVLDKIKVAN--ESTLAD 1062

Query: 993  LQAE---MIELRQ--TNQVFQEENGK-----MLDEKNSLCRNV----SDLKDAKSSAEDE 1038
            LQ E   + E+R+  + Q+   EN K       DE   L   V    S++   K++ E E
Sbjct: 1063 LQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESE 1122

Query: 1039 NSVMFHD----VLALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKN 1094
             + M  +    +  L   +   E+   E + EK  L      L     DL Q+   + ++
Sbjct: 1123 RAAMIREKQNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSIERD 1182

Query: 1095 FE-VKEAENVYLNE-------------SIERMDKELLEMDKRLKAAETSNAEFSRHIEEL 1140
             E +K  +  + NE               + ++K  LE     +  E   A+  +  EE+
Sbjct: 1183 SESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEI 1242

Query: 1141 KMEQEESTKIKENLDR---QILEQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHR 1197
                EE  K ++ +D    +I ++ E   + + ++E            ++  L E++Q R
Sbjct: 1243 NTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQQKR 1302

Query: 1198 VREEALNLELLNKENEFKLWENEAAAFYHDLQMSSICLALLESKVSELTGVCKILDDESS 1257
               E + ++ +  + E K    E      DL+M    +A ++ +  E+     +L+ E  
Sbjct: 1303 NALEKMKIK-IQLDKETKRLSEEIELKVKDLEME---MADMKRQKQEIEDTKGLLEKEKQ 1358

Query: 1258 AKSLENEHMREIISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLEHISLLWTKRNSVVGN 1317
                E + + + +  L  E    +E+ +  + L + L++     E +    T   S +  
Sbjct: 1359 ELKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEE 1418

Query: 1318 GAQKDVVIETCLRKHSHQSARENEIVLIPDGVSDLLTLQTRIR-AVEKIMMEELKRRVKQ 1376
               K    +    +   ++ +E E +     + +L T++T ++   EKI  E+   ++++
Sbjct: 1419 MQLKIFKQQRLNDQTREENKKEKESLEQQRAMEELETIKTELKERQEKIQTEQ--EKLEE 1476

Query: 1377 KSLTTESTPYSSLEIATYPKVENRKKEIELVEENVFDRNSWRKKPKIRLLMKDIPLDRNV 1436
            + L  +    +  ++    K +  K EI   +  V        + +      DI  ++  
Sbjct: 1477 EKLLVQIEAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIE-EQIQ 1535

Query: 1437 DDQNSKYLKREHRRTNDHVLELCENNEHEPLSAPTVDHAMICHRSDDSGRYLNYSSELDI 1496
            +++N+K+L  + R+  D      +  +     A  +D  MI HR +           LD 
Sbjct: 1536 NNENAKHLLEQERKDID------KQKQELQKQADDLDMRMIAHRENVE----MSKRSLDE 1585

Query: 1497 EKELGVDKLELSKSVKEKTEDDKRRILERLSSDGQKLAILKMALQDLKKKTETKKKSKQG 1556
            EK+L    LE   +   +  DD  +  E +     KL +L+  +Q+  K  E  K    G
Sbjct: 1586 EKKL----LEQKANEILRQRDDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDG 1641

Query: 1557 NDIEYETVKRHIEEVEEAVMQQVSINDQMAKNVEEGASSLDR-----EIPRRGSEQIGKL 1611
               E    ++ +EE   A+ ++    + M  + E+    ++      ++ R+  +QI K 
Sbjct: 1642 KRNEINKEQQRLEESLRAINEEKGDLEIMRADYEKQEQQIEEMRVEAKMERKELDQIKKT 1701

Query: 1612 QFEVQ 1616
              E++
Sbjct: 1702 LKEME 1706



 Score =  182 bits (461), Expect = 1e-43
 Identities = 285/1371 (20%), Positives = 601/1371 (43%), Gaps = 210/1371 (15%)

Query: 141  ERSSEESNGEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDDRA 200
            E+  E +  ++Q  RE L KM  +      + +   E +++ + +L++ +   + L    
Sbjct: 583  EKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQ-- 640

Query: 201  SEAEIQVEILKESLMQL---KADKDAGEVLYNQCLETIARLESMLSQKDNIEAKNLKQEL 257
             E E + EI+ ++  QL   +++ D  +   N  +ET+      L  KD  E +  KQE+
Sbjct: 641  -ELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLD-KDKEEMEEQKQEM 698

Query: 258  TRVVVQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMN 317
             +   ++D +    K   E + M++ +  + EE      +++E+ ++E+E    ++ ++ 
Sbjct: 699  EK---ERDNMDQSRKSLDEDLKMMKLQKQVIEEEK----NKLEQMKIELEREADDIRKIK 751

Query: 318  EERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEIS----EKHRGMLE 373
            EE  +   +     E++ K   ++ H+ E+ ++ KN +++     E S    +K +  LE
Sbjct: 752  EETQNKRQILEKMAEELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLE 811

Query: 374  KSNQNLQLEAENLVQ---RIASKDHELLEKHTEIERLQTLMHGEHSNFIQIESAL----Q 426
            +  +N+  + E++ +   +I  ++ EL +   EI + Q+    E SN  +  +A+    +
Sbjct: 812  EMKENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVE 871

Query: 427  ALQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVE-ENKTLHE------ 479
             LQ       ++  +L L+ +      ++L+  K + + E   I + + +T HE      
Sbjct: 872  DLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEE 931

Query: 480  --LNFSSTRSLKKQQMEISK--LKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNE 535
               +F  T + +++Q++ +K  ++E K+++E++     +    L  +   +K   Q L E
Sbjct: 932  MTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEE 991

Query: 536  RYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDMNEVLME 595
                + +    L    +  +    + QNE   L++       E+E L E+ K  N+VL +
Sbjct: 992  EKNKLEQMKIGLEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDK 1051

Query: 596  -NACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTL----LSQLQIITE 650
                 E +L  L  E   L    + I +  + ++ EK     EKS L    L +LQ   +
Sbjct: 1052 IKVANESTLADLQKEKRILEEMRENISKQIEDIENEK-----EKSKLREDELKKLQTEVQ 1106

Query: 651  SMQKILENNTVLEKSLSDAKIE-----FEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLI 705
              Q  ++      +S   A I         L+ KS D+E   K +  EK  L N+R++L 
Sbjct: 1107 KQQSEIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLK 1166

Query: 706  SQLEIVEEKLSNLEKKVTNL---------------------------------------- 725
              +E +++KL ++E+   +L                                        
Sbjct: 1167 KDVEDLQQKLMSIERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQ 1226

Query: 726  --EEKYADVEKDKESAVNQVEELFASILVQKENHSN---HKHSSEARLANLEN------- 773
              EEK A ++K++E     VEE+     +  E+++     K + E+  ++LE        
Sbjct: 1227 RVEEKTAQIQKEREEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKSQTFK 1286

Query: 774  --------IVRVLQEEQRLGKVEFEQELDR------------VVNAQIEMFILQNCIEEL 813
                    +  + Q+   L K++ + +LD+            V + ++EM  ++   +E+
Sbjct: 1287 QNKNIEIALAEIQQKRNALEKMKIKIQLDKETKRLSEEIELKVKDLEMEMADMKRQKQEI 1346

Query: 814  ELKNFVLLTECEKLVEASK---------FSDKVISELESENLM-------------QLIE 851
            E    +L  E ++L +  K           +K  +E E  NLM             ++++
Sbjct: 1347 EDTKGLLEKEKQELKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKENEIVK 1406

Query: 852  EEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQE 911
            E+  L +    +M + K+    +++     +N+ +KE +   R ++++E++++ L + QE
Sbjct: 1407 EKLTLEKSNIEEMQL-KIFKQQRLNDQTREENKKEKESLEQQRAMEELETIKTELKERQE 1465

Query: 912  ---------ENQQLLV--ENSVLLGSLQQHQSEGEKLKLEK---KTVEQEFENMREQNVI 957
                     E ++LLV  E   L   L++ + + EKL++ +   K ++++ EN RE+   
Sbjct: 1466 KIQTEQEKLEEEKLLVQIEAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETER 1525

Query: 958  LQKDKVELLEEN---RQLRIEVVNGVEKENRSKSTLAA-LQAEMIELRQTNQVFQ---EE 1010
             + D  E ++ N   + L  +    ++K+ +     A  L   MI  R+  ++ +   +E
Sbjct: 1526 KKCDIEEQIQNNENAKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDE 1585

Query: 1011 NGKMLDEK-NSLCRNVSDLKDAKSSAEDENSVMFHDVLA--LSNLN-----LVYEIFFTE 1062
              K+L++K N + R   DL+  K     + + +  DVL   + N N     + YE+    
Sbjct: 1586 EKKLLEQKANEILRQRDDLEKEKEDMMKKWNKL--DVLQNEMQNENKAMEEIKYELDGKR 1643

Query: 1063 NMV--EKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIERMDKELLEMD 1120
            N +  E++ L E L  ++    DL     ++R ++E +E +   +    +   KEL ++ 
Sbjct: 1644 NEINKEQQRLEESLRAINEEKGDLE----IMRADYEKQEQQIEEMRVEAKMERKELDQIK 1699

Query: 1121 KRLKAAETSNAEFSRHIEELKMEQEESTKIKENLDRQILEQSENCMNHKKEIEHLNEANE 1180
            K LK  E   A   +  EE+K   EE+ + KE+L++     +E   + + + + L +  E
Sbjct: 1700 KTLKEME---AYLEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQERE 1756

Query: 1181 TLQFEMKTLLHEVEQ-----HRVREEALNLELLNKENEFKLWENEAAAFYHDLQMSSICL 1235
             +  + K L   +++      + +EE L  E   KE+   L E +A    + L+M +   
Sbjct: 1757 EINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKA----NILEMKT--- 1809

Query: 1236 ALLESKVSELTGVCKILDDESSAK---SLENEHMREIISLLE---SEIGGLKEQLSAYVP 1289
               +++  E+    +  ++E   +    +E + + +I S LE   SE+   +++L+    
Sbjct: 1810 ---KAEPEEIKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQKKLNDDKK 1866

Query: 1290 LVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVI-ETCLRKHSHQSARE 1339
            ++   KED   ++  S +  +R  +    ++ D  I +T L KH  ++++E
Sbjct: 1867 MIEQEKEDLEKMK--SEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKE 1915



 Score =  159 bits (403), Expect = 5e-37
 Identities = 236/1102 (21%), Positives = 475/1102 (42%), Gaps = 215/1102 (19%)

Query: 145  EESNGEVQTLREALAKMQSDKDALFLQYQESLENLSKM----ETDLNKAQNNARGLDDRA 200
            EE+  E Q L +    ++ +++ L  + +   + L K+    E+ L   Q   R L++  
Sbjct: 1015 EETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLADLQKEKRILEEMR 1074

Query: 201  SEAEIQVEILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIEAKNLKQELTRV 260
                 Q+E        ++ +K+  ++  ++  +    ++   S+ D +E  N++ E   +
Sbjct: 1075 ENISKQIE-------DIENEKEKSKLREDELKKLQTEVQKQQSEID-MEKTNIESERAAM 1126

Query: 261  VVQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEER 320
            + +K  ++ + K+  E + M   +I   +E   +L++     + +VE L++ L  M+ ER
Sbjct: 1127 IREKQNMMTELKKKSEDVEMQMKEILTEKE---LLHNDRNLLKKDVEDLQQKL--MSIER 1181

Query: 321  DSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEA---EKLEISEKH-RGMLEKSN 376
            DS S+     L+K    ENE    +E  +Q+K  ++ +A   EK+++   H R  +E+  
Sbjct: 1182 DSESLK----LDK-EAFENE----KEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKT 1232

Query: 377  QNLQLEAEN---LVQRIASKDHELLEKHTEIERLQTLMHGEHSNFIQIESALQALQKLYS 433
              +Q E E    LV+ I  K   + E +TEI + +  +  + S+          L+K  S
Sbjct: 1233 AQIQKEREEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSD----------LEKAKS 1282

Query: 434  QSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQQM 493
            Q+ K+ +N+ + L        +++  K++  E+M+  ++ +K    L+      +K  +M
Sbjct: 1283 QTFKQNKNIEIALA-------EIQ-QKRNALEKMKIKIQLDKETKRLSEEIELKVKDLEM 1334

Query: 494  EISKLKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQSLGLNPNS 553
            E++ +K  K+++E       +E   L++E  +++D +  L    Q   E+  +L    N 
Sbjct: 1335 EMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQETEEERNNLMALKNQ 1394

Query: 554  FAASVRDLQNENFMLKETCKKEHSEKEAL--------------REKSKDMNEVLMENACM 599
                + DL+ EN ++KE    E S  E +              RE++K   E L +   M
Sbjct: 1395 ----LEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENKKEKESLEQQRAM 1450

Query: 600  EFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESMQKILENN 659
            E        EL+ ++  +KE Q+  Q  QE+   L +EK  +    QI  E++ K+LE  
Sbjct: 1451 E--------ELETIKTELKERQEKIQTEQEK---LEEEKLLV----QIEAENLNKVLE-- 1493

Query: 660  TVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVEEKLSNLE 719
                    + K + E L I   DL    K++ ++  N + E          +EE++ N E
Sbjct: 1494 --------EIKRQQEKLEISEADL----KVMKEQCENAREETERKKCD---IEEQIQNNE 1538

Query: 720  KKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHSNHKHSSEARLANLENIVRVLQ 779
                 LE++  D++K K+    Q ++L   ++  +EN    K S              L 
Sbjct: 1539 NAKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRS--------------LD 1584

Query: 780  EEQRLGKVEFEQELDRVVNAQIEMFILQNCIEELELKNFVLLTECEKLVEASKFSDKVIS 839
            EE++L     EQ+ + ++  +          ++LE +   ++ +  KL       D + +
Sbjct: 1585 EEKKL----LEQKANEILRQR----------DDLEKEKEDMMKKWNKL-------DVLQN 1623

Query: 840  ELESENLMQLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKI 899
            E+++EN  + +EE        K+++D              G  NEI KE+          
Sbjct: 1624 EMQNEN--KAMEEI-------KYELD--------------GKRNEINKEQ---------- 1650

Query: 900  ESLESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQ 959
            + LE SL    EE   L +  +      QQ +    + K+E+K ++Q  + ++E    L+
Sbjct: 1651 QRLEESLRAINEEKGDLEIMRADYEKQEQQIEEMRVEAKMERKELDQIKKTLKEMEAYLE 1710

Query: 960  KDKVEL---LEENRQLRIEV------VNGVEKENRSKSTLAALQAEMI--ELRQTNQVFQ 1008
            K+K E+    EE R+ + ++      +N  +++ RS+  L   + E I  + +Q  Q   
Sbjct: 1711 KEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRID 1770

Query: 1009 EENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVLALSNLNLVYEIFFTENMVEKR 1068
            E + ++  +K        ++K+ + S E+  +                      N++E +
Sbjct: 1771 EFDAQVSKQKEEDLPKEKEMKEDRKSLEETKA----------------------NILEMK 1808

Query: 1069 ALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIERMDKELLEMDKRL----K 1124
               E          +  +E   +R   E++  E   +   +ER+  E+    K+L    K
Sbjct: 1809 TKAEP--EEIKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQKKLNDDKK 1866

Query: 1125 AAETSNAEFSRHIEELKMEQEESTKIKENLDRQILEQSENCMNHKKEIEHLNEANETLQF 1184
              E    +  +   E+  ++++  + +  LD++I +        K +IE+  E  E L  
Sbjct: 1867 MIEQEKEDLEKMKSEIMKQRQQMEEERSELDKKIKQTDLE----KHDIENSKEIVEKLMV 1922

Query: 1185 EMKTLLHEVEQHRVREEALNLE 1206
            E++   HE++    ++E L++E
Sbjct: 1923 EVEKQKHEIQ---FQKEELDIE 1941



 Score =  123 bits (309), Expect = 4e-26
 Identities = 200/942 (21%), Positives = 400/942 (42%), Gaps = 160/942 (16%)

Query: 38   TKVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHAMGELRHAH 97
            T++K   + +E +        E+ +  R  L K VE+  +   ++ ER   ++       
Sbjct: 1135 TELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSI-ERDSESL------- 1186

Query: 98   KTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKNERSSE--ESNGEVQTLR 155
            K   EAF N    +    +       + E         R +  E++++  +   E+ TL 
Sbjct: 1187 KLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLV 1246

Query: 156  EALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNA----RGLDDRASEAEIQVEILK 211
            E + K +   D  + + ++  E +    +DL KA++      + ++   +E + +   L+
Sbjct: 1247 EEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQQKRNALE 1306

Query: 212  ESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIEAKNLKQELTRVVVQKDTVLLQY 271
            +  ++++ DK+                   LS++  ++ K+L+ E+  +  QK  +    
Sbjct: 1307 KMKIKIQLDKET----------------KRLSEEIELKVKDLEMEMADMKRQKQEI---- 1346

Query: 272  KQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEERDSLSVLYHHCL 331
                      E+   L E+  + L  + +  E ++  L +   E  EER++L  L +  L
Sbjct: 1347 ----------EDTKGLLEKEKQELKQEKKELEDQMMDLTREKQETEEERNNLMALKNQ-L 1395

Query: 332  EKISKMENEILHVQ-----ENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQLEAENL 386
            E + K ENEI+  +      N E+++ KI K+ ++L    +     EK +    LE +  
Sbjct: 1396 EDLRK-ENEIVKEKLTLEKSNIEEMQLKIFKQ-QRLNDQTREENKKEKES----LEQQRA 1449

Query: 387  VQRIASKDHELLEKHTEIERLQTLMHGEHSNFIQIESALQALQKLYSQSQKEQRNLALEL 446
            ++ + +   EL E+  +I+  Q  +  E    +QIE+  + L K+  + +++Q  L +  
Sbjct: 1450 MEELETIKTELKERQEKIQTEQEKLE-EEKLLVQIEA--ENLNKVLEEIKRQQEKLEIS- 1505

Query: 447  KYGLLLLKD--------LELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEISKL 498
            +  L ++K+         E  K D +E++Q     N+    L     + + KQ+ E+ K 
Sbjct: 1506 EADLKVMKEQCENAREETERKKCDIEEQIQN----NENAKHLLEQERKDIDKQKQELQKQ 1561

Query: 499  KEI--------KEKLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQSLGLN 550
             +         +E +E    +  EE  +L+++ ++I      L +  + M+++   L + 
Sbjct: 1562 ADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNKLDVL 1621

Query: 551  PNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDMNEVLMENACMEFSLLGLNDE- 609
             N       ++QNEN  ++E  K E   K          NE+  E   +E SL  +N+E 
Sbjct: 1622 QN-------EMQNENKAMEEI-KYELDGKR---------NEINKEQQRLEESLRAINEEK 1664

Query: 610  --LDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESMQKILENNTVLEKSLS 667
              L+ +R   ++ +Q  Q+  EE  + A  +   L Q++   + M+  LE      KS++
Sbjct: 1665 GDLEIMRADYEKQEQ--QI--EEMRVEAKMERKELDQIKKTLKEMEAYLEKEKEEMKSIT 1720

Query: 668  DAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEE 727
                  E  R +  DLE     +N++K +L+++R +L  + E +  K   L++++   +E
Sbjct: 1721 ------EETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRI---DE 1771

Query: 728  KYADVEKDKESAVNQVEELFASILVQKENHSNHKHSSEARLANLENIVRVLQEEQRLGKV 787
              A V K KE  + +          +KE   + K   E +   LE   +   EE +  K 
Sbjct: 1772 FDAQVSKQKEEDLPK----------EKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKE 1821

Query: 788  EFEQELDRVVNAQIEMFILQNCIEELELKNFVLLTECEKLVEASKFSDKVISELESENLM 847
            + E+E +  V  ++E   ++    +LE     +  E +KL +     DK + E E E+L 
Sbjct: 1822 KEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQKKLND-----DKKMIEQEKEDL- 1875

Query: 848  QLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLV 907
                         K K +I K               + ++ E   S +  KI+  ++ L 
Sbjct: 1876 ------------EKMKSEIMK---------------QRQQMEEERSELDKKIK--QTDLE 1906

Query: 908  KSQEENQQLLVENSVLLGSLQQH--QSEGEKLKLEKKTVEQE 947
            K   EN + +VE  ++    Q+H  Q + E+L +E++ +  E
Sbjct: 1907 KHDIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADE 1948



 Score =  120 bits (300), Expect = 5e-25
 Identities = 209/1013 (20%), Positives = 412/1013 (40%), Gaps = 123/1013 (12%)

Query: 33   LTDIDTKVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAE---RYDHA 89
            L +   K++ M   +E EAD  ++  E    +R  L K+          LAE   R +  
Sbjct: 989  LEEEKNKLEQMKIGLEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQV 1048

Query: 90   MGELRHAHKTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKNERSSEESNG 149
            + +++ A+++           +            D E+        +SK  E   ++   
Sbjct: 1049 LDKIKVANESTLADLQKEKRILEEMRENISKQIEDIENEKE-----KSKLREDELKKLQT 1103

Query: 150  EVQTLREAL----AKMQSDKDALFLQYQESLENLSK----METDLNKAQNNARGLDDRAS 201
            EVQ  +  +      ++S++ A+  + Q  +  L K    +E  + +       L +  +
Sbjct: 1104 EVQKQQSEIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEMQMKEILTEKELLHNDRN 1163

Query: 202  EAEIQVEILKESLMQLKADKDAGEV---LYNQCLETIARLESMLS-QKDNIEAKNLKQEL 257
              +  VE L++ LM ++ D ++ ++    +    E + ++++ L  Q D IE   L+   
Sbjct: 1164 LLKKDVEDLQQKLMSIERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHH 1223

Query: 258  TRVVVQKDTVLLQYKQCLEKIPMLENKIA----LAEENSRMLNDQIERTELEVETLRKNL 313
             R  V++ T  +Q ++  E+I  L  +I     + +E+   +  + E  E +   L K  
Sbjct: 1224 ERQRVEEKTAQIQKER--EEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAK 1281

Query: 314  AEMNEERDSLSVLYHHCLEKISKMENEILHVQENAE--QLKNKIEKEAEKLEIS------ 365
            ++  ++  ++ +      +K + +E   + +Q + E  +L  +IE + + LE+       
Sbjct: 1282 SQTFKQNKNIEIALAEIQQKRNALEKMKIKIQLDKETKRLSEEIELKVKDLEMEMADMKR 1341

Query: 366  -----EKHRGMLEKSNQNLQLEAENLVQRIASKDHELLEKHTEIERLQTLMHG------- 413
                 E  +G+LEK  Q L+ E + L  ++     E  E   E   L  L +        
Sbjct: 1342 QKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKE 1401

Query: 414  ----------EHSNFIQIESALQALQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQDF 463
                      E SN  +++  +   Q+L  Q+++E +     L+    + ++LE  K + 
Sbjct: 1402 NEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENKKEKESLEQQRAM-EELETIKTEL 1460

Query: 464  KEEMQGIVEENKTLHE---LNFSSTRSLKKQQMEISKLKEIKEKLEREFHTSTEESNVLQ 520
            KE  + I  E + L E   L      +L K   EI + +E  E  E +     E+    +
Sbjct: 1461 KERQEKIQTEQEKLEEEKLLVQIEAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAR 1520

Query: 521  RETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKE 580
             ET + K DI+          EQ+Q+               +N   +L++  K    +K+
Sbjct: 1521 EETERKKCDIE----------EQIQNN--------------ENAKHLLEQERKDIDKQKQ 1556

Query: 581  ALREKSKDMN-EVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKS 639
             L++++ D++  ++     +E S   L++E   L     EI +    L++EK    ++  
Sbjct: 1557 ELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEKEK----EDMM 1612

Query: 640  TLLSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKSGD----LEDCCKLLNDEKN 695
               ++L ++   MQ   EN     K++ + K E +G R +       LE+  + +N+EK 
Sbjct: 1613 KKWNKLDVLQNEMQN--EN-----KAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKG 1665

Query: 696  NLQNERSMLISQLEIVEE-------KLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFA 748
            +L+  R+    Q + +EE       +   L++    L+E  A +EK+KE   +  EE   
Sbjct: 1666 DLEIMRADYEKQEQQIEEMRVEAKMERKELDQIKKTLKEMEAYLEKEKEEMKSITEETRR 1725

Query: 749  SILVQKENHSNHKHSSEARLANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQN 808
                  E  S H +  +  L +  +++   +EE      + +Q +D   +AQ+     ++
Sbjct: 1726 Q-KEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEF-DAQVSKQKEED 1783

Query: 809  CIEELELKNFVLLTE------CEKLVEASKFSDKVISELESENLMQLIEEEFLLHRIRKF 862
              +E E+K      E       E   +A     K   E E E     ++ E     I + 
Sbjct: 1784 LPKEKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEIEQI 1843

Query: 863  KMDIHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSV 922
            K  + +V   +        D+E KK       I  + E LE    +  ++ QQ+  E S 
Sbjct: 1844 KSQLERVRSEM--------DHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSE 1895

Query: 923  LLGSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIE 975
            L   ++Q   E   ++  K+ VE+    + +Q   +Q  K EL  E +++  E
Sbjct: 1896 LDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADE 1948



 Score =  109 bits (273), Expect = 6e-22
 Identities = 191/1103 (17%), Positives = 456/1103 (41%), Gaps = 159/1103 (14%)

Query: 657  ENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVEEKLS 716
            E N  +E+ +   + + + L  +  DLE     L   K +L+ ++   +++++   E L 
Sbjct: 1    EKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLE 60

Query: 717  NLEKKV-------------------------TNLEEKYADVEKDKE-------------- 737
             + + +                         T ++    ++EK+KE              
Sbjct: 61   KMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQS 120

Query: 738  ------SAVNQVEELFASILVQ----KENHSNHKHSSEARLANLENIVRVLQEEQ---RL 784
                  + +N + E   +   Q    KE     K   E    N++   + L E+Q   +L
Sbjct: 121  ELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKL 180

Query: 785  GKVEFEQELDRVVNAQIEM----FILQNCIEELELKNFVLLTECEKLVEASKFSDKVISE 840
             K  FE+E +++   +IE+      +    EE + K   L    E+L+   +   K   +
Sbjct: 181  QKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIREKEKLKKKSED 240

Query: 841  LESENLMQLIEEEFLLHRIRKF-----------KMDIHKVCGVLQIDSDGGGDNE---IK 886
            +E + + +++ E+ LLH  RK             +D+ +    L++D +   +NE   +K
Sbjct: 241  VEIQ-MKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDRE-AFENEKEAMK 298

Query: 887  KEEIPISRILDKIESL----ESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLEKK 942
            + +  +    D+IE +    +    + +E   Q+  E   +   +++   +   L  + +
Sbjct: 299  QMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRKDMVLNEKNR 358

Query: 943  TVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKENRSKSTLAALQAEMIELRQ 1002
             +E++ ++++    +L+K++   LE+ R    +V   +EK+   ++TLA +Q E  ++ +
Sbjct: 359  DIEEKIKSIQSDKDMLEKER-HNLEKTRSELYKVKEDLEKQ--KENTLAEIQKEREDVEK 415

Query: 1003 TNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVLALSNLNLVYEIFFTE 1062
             N+    E  ++  ++  + +   +L   K+  ++    +  +   +      +++  +E
Sbjct: 416  MNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQFDLRQSE 475

Query: 1063 NMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIERMDKEL------ 1116
               ++  + + +  + +    L+++   + +  +  E E    ++S + +DK+L      
Sbjct: 476  LDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDKDLKMMKLQ 535

Query: 1117 ---------LEMDKRLKAAETSNAEFSRHIEELKMEQEESTKIKENLDRQILEQSENCMN 1167
                      +++K++K+ ++      +   +L+  + E  K+KE+L++    Q EN + 
Sbjct: 536  KQVFEEEKNKDIEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEK----QKENTLA 591

Query: 1168 H-KKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLELLNKENEFKLWENEAAAFYH 1226
              +KE E L + NE +  EM  + H+ EQ   +++ L+      +N  +  E E      
Sbjct: 592  QIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMK 651

Query: 1227 DLQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMREIISLLESEIGGLKEQLSA 1286
                     + L+ + + +  + + + +E      + E M E    +E E   + +    
Sbjct: 652  ARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSR-- 709

Query: 1287 YVPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVIETCLRKHSHQSARENEIVLIP 1346
                  SL ED   ++                 QK V+ E   +    +   E E     
Sbjct: 710  -----KSLDEDLKMMK----------------LQKQVIEEEKNKLEQMKIELERE----A 744

Query: 1347 DGVSDLLTLQTRIRAVEKIMMEELKRRVKQKSLTTEST-----PYSSLEIATYPKVENRK 1401
            D +  +       R + + M EELK+  K  +   E T         +++A    + + +
Sbjct: 745  DDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQ 804

Query: 1402 KE---IELVEENVFDRNSWRKKPKIRLLMKDIPLDRNVDDQNSKYLKREHRRTNDHVLEL 1458
            KE   +E ++EN+  +    +K K ++ +++  L++   + + +  + E  ++N      
Sbjct: 805  KEKSNLEEMKENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERA 864

Query: 1459 CENNEHEPLSAPTVDHAMICHRSD-DSGRYLNYSSEL-DIEKELGVDKLELSKSVKEKTE 1516
                + E L +  +           D   + N   EL  ++ EL  +  E+ K +K +T+
Sbjct: 865  AIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIEK-IKLETQ 923

Query: 1517 DDKRRI-------LERLSSDGQKLAILKMALQDLKKKTETKKKSKQGNDIEYETVKRHIE 1569
             +++R+       +E ++++ ++L   K+ +++ K++ E K+        + +  ++ ++
Sbjct: 924  HERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRD-------DMDQSRKSLD 976

Query: 1570 EVEEAVMQQVSINDQMAKNVEEGASSLDREIPRRGSEQIGKLQFEVQNIQYILLKLA--- 1626
            E  + +  Q  + ++    +E+    L+RE     +++I K++ E QN +  L K+A   
Sbjct: 977  EDLKMMKAQKQVLEEEKNKLEQMKIGLERE-----ADEISKIKEETQNERQNLEKMANAL 1031

Query: 1627 EENNNKVKNRISRKTGILLRRKL 1649
            +E    +   I RK  +L + K+
Sbjct: 1032 KEEREYLAEEIKRKNQVLDKIKV 1054



 Score =  108 bits (271), Expect = 1e-21
 Identities = 195/1000 (19%), Positives = 429/1000 (42%), Gaps = 118/1000 (11%)

Query: 693  EKN-NLQNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASIL 751
            EKN +++ +   + S  +++E++  +LEK  + L +   D+EK KE+ + ++++    + 
Sbjct: 1    EKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLE 60

Query: 752  VQKENHSNH----KHSSEARLANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQ 807
               EN +      KH  E      + + ++  E Q L + E E+E + ++  + ++ + Q
Sbjct: 61   KMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNL-QQELEKEKEIIMKDRSQLDLRQ 119

Query: 808  NCIEELELKNFVLLTECEKLVEASKFSDKVISELESENLMQLIEEEFLLHRIRKFKMDIH 867
            +   EL+ +   +    E +    K  DK   E+E E   ++ +E   + + RK  +D  
Sbjct: 120  S---ELDKQQTNMNDIMETMKNERKQLDKDKEEME-EQKQEMEKERDNMDQSRK-SLDED 174

Query: 868  KVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSVLLGSL 927
            +    LQ        N++++ +I + R  D+I     S +K + +N++  +E        
Sbjct: 175  QKKMKLQKQMFEEEKNKLEQMKIELEREADEI-----SKIKEETQNKRQRLEK------- 222

Query: 928  QQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKENRSK 987
               +   EK KL+KK+ + E + M+E  ++ +K   ELL  +R+L    V  ++++    
Sbjct: 223  MTEELIREKEKLKKKSEDVEIQ-MKE--ILTEK---ELLHNDRKLLTRDVENLQQK---- 272

Query: 988  STLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVL 1047
              L  L+ +   L+   + F+ E   M   K  L     +++  K   + +   +     
Sbjct: 273  --LIDLERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAA 330

Query: 1048 AL----SNLNLVYEIFFTENMV---EKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEA 1100
             +      +N + E    ++MV   + R + E + ++    + L +E    R N E   +
Sbjct: 331  QIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKE----RHNLEKTRS 386

Query: 1101 ENVYLNESIERM-DKELLEMDKRLKAAETSNAEFSRHIEELKMEQEESTKIK-------- 1151
            E   + E +E+  +  L E+ K  +  E  N   +R + E+K ++E+  + +        
Sbjct: 387  ELYKVKEDLEKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKT 446

Query: 1152 --ENLDRQILEQSENCMNHKKEIE----HLNEANETLQFEMKTLLHEVEQHRVREEALNL 1205
              +NL +++ ++ E  M  + + +     L++    +   M+T+ +E +Q    +E +  
Sbjct: 447  EIQNLQQELEKEKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 506

Query: 1206 ELLNKENEFKLWENEAAAFYHDLQMSSICLALL-ESKVSELTGVCKILDDESSAKSLENE 1264
            +    E E   ++    +   DL+M  +   +  E K  ++    K +  +      E  
Sbjct: 507  QKQEMEKEKHDFDQSRKSLDKDLKMMKLQKQVFEEEKNKDIEKKIKSIQSDKDMLEKEKH 566

Query: 1265 HMREIISLLESEIGGLKEQLSAYVPLVSSLKEDFNSL-EHIS--LLWTKRNSVVGNGAQK 1321
             + +  S L      L++Q    +  +   +ED   + E+I+  +   K      N  Q 
Sbjct: 567  DLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQD 626

Query: 1322 DV-VIETCLRKHSHQSARENEIVL-----IPDGVSDLLTLQTRIRAVEKIMMEELKRRVK 1375
            ++  ++T ++    +  +E EI++     +    S+L   QT +  + + M  E K+  K
Sbjct: 627  ELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDK 686

Query: 1376 QKSLTTESTPYSSLEIATYPKVENRKKEIELVEENV-FDRNSWRKKPKIRLLMKDIPLDR 1434
             K                  ++E +K+E+E   +N+   R S  +  K+  L K +    
Sbjct: 687  DKE-----------------EMEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQKQV---- 725

Query: 1435 NVDDQNSK--YLKREHRRTNDHVLELCENNEH---------EPLSAPTVDHAMICHRSDD 1483
             ++++ +K   +K E  R  D + ++ E  ++         E L     D   + H ++D
Sbjct: 726  -IEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKD---VAHLAED 781

Query: 1484 SGRYLNYSSELDIEKELGVDKLELSKSVKEKTEDDKRRILERLSSDGQKLAILKMALQDL 1543
            + R  N   E+ +  E  +  L+  KS  E+ +++  +  E +  +  K+ + +  L+ L
Sbjct: 782  TKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLREDELEQL 841

Query: 1544 KKKTETKKKSKQGNDIEYETVKRHIEEVEEAVMQQVSINDQMAKNVEEGASS--LDREIP 1601
            + +       KQ ++ E E  K +IE    A+++ V        +++  A S  LDRE  
Sbjct: 842  QAEIH-----KQQSETEIE--KSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAF 894

Query: 1602 RRGSEQIGKLQFEVQNIQYILLKLAEENNNKVKNRISRKT 1641
                E++ +++ E++     + K+  E  ++ + R+   T
Sbjct: 895  ENEKEELKQMKTELEREADEIEKIKLETQHE-RQRVEEMT 933



 Score = 86.7 bits (213), Expect = 6e-15
 Identities = 110/614 (17%), Positives = 263/614 (41%), Gaps = 98/614 (15%)

Query: 139  KNERSSEESNGEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDD 198
            + ++ +EE    +  L+  L  ++ + + +  +      N+ +M+  + K Q     L+D
Sbjct: 1376 REKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQR----LND 1431

Query: 199  RASEAEIQVEILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIEAKNLKQELT 258
            +  E   +    KESL Q +A ++         LETI        +K   E + L++E  
Sbjct: 1432 QTREENKKE---KESLEQQRAMEE---------LETIKTELKERQEKIQTEQEKLEEEKL 1479

Query: 259  RVVVQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNE 318
             V ++ + +     + LE+I   + K+ ++E + +++ +Q E    E E  + ++ E  +
Sbjct: 1480 LVQIEAENL----NKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQ 1535

Query: 319  ERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQN 378
              ++   L     + I K + E+   Q+ A+ L  ++    E +E+S++    L++  + 
Sbjct: 1536 NNENAKHLLEQERKDIDKQKQEL---QKQADDLDMRMIAHRENVEMSKRS---LDEEKKL 1589

Query: 379  LQLEAENLVQR---IASKDHELLEKHTEIERLQTLMHGEHSNFIQIESALQALQKLYSQS 435
            L+ +A  ++++   +  +  ++++K  +++ LQ  M  E+    +I+  L   +   ++ 
Sbjct: 1590 LEQKANEILRQRDDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKR---NEI 1646

Query: 436  QKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEI 495
             KEQ+ L   L+       DLE+ + D++++ Q I E                K ++ E+
Sbjct: 1647 NKEQQRLEESLRAINEEKGDLEIMRADYEKQEQQIEEMRV-----------EAKMERKEL 1695

Query: 496  SKLKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQ----HLNERYQAMLEQL------- 544
             ++K+  +++E       EE   +  ET + K+D++    H+NE+ Q +  Q        
Sbjct: 1696 DQIKKTLKEMEAYLEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQER 1755

Query: 545  -------QSLGLNPNSFAASV-----------RDLQNENFMLKET------CKKEHSEKE 580
                   + L    + F A V           ++++ +   L+ET       K +   +E
Sbjct: 1756 EEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEE 1815

Query: 581  ALREKSKDMNEVLME--------------------NACMEFSLLGLNDELDGLRGTVKEI 620
              +EK K+  E  M                      + M+     LND+   +    +++
Sbjct: 1816 IKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDL 1875

Query: 621  QQFCQVLQEEKSILADEKSTLLSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKS 680
            ++    + +++  + +E+S L  +++        I  +  ++EK + + + +   ++ + 
Sbjct: 1876 EKMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQK 1935

Query: 681  GDLEDCCKLLNDEK 694
             +L+   + + DE+
Sbjct: 1936 EELDIERQKIADEQ 1949



 Score = 70.1 bits (170), Expect = 5e-10
 Identities = 98/517 (18%), Positives = 231/517 (43%), Gaps = 42/517 (8%)

Query: 137  SKKNERSSEESNGEVQTLREALAKMQSDKDALF---LQYQESLENLSKMETDLNKAQN-- 191
            S + +R+ EE       L+E   K+Q++++ L    L  Q   ENL+K+  ++ + Q   
Sbjct: 1443 SLEQQRAMEELETIKTELKERQEKIQTEQEKLEEEKLLVQIEAENLNKVLEEIKRQQEKL 1502

Query: 192  ---------------NARGLDDRAS---EAEIQV-EILKESLMQLKADKDAG-EVLYNQC 231
                           NAR   +R     E +IQ  E  K  L Q + D D   + L  Q 
Sbjct: 1503 EISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKHLLEQERKDIDKQKQELQKQA 1562

Query: 232  LETIARLESMLSQKDNIE-AKNLKQELTRVVVQKDTVLLQYKQCLEKIP--MLE--NKIA 286
             +   R   M++ ++N+E +K    E  +++ QK   +L+ +  LEK    M++  NK+ 
Sbjct: 1563 DDLDMR---MIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNKLD 1619

Query: 287  LAEENSRMLNDQIERTELEVETLRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHVQE 346
            + +   +  N  +E  + E++  R    E+N+E+  L       L  I++ + ++  ++ 
Sbjct: 1620 VLQNEMQNENKAMEEIKYELDGKRN---EINKEQQRLE----ESLRAINEEKGDLEIMRA 1672

Query: 347  NAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQLEAENLVQRIASKDHELLEKHTEIER 406
            + E+ + +IE+   + ++  K    ++K+ + ++   E   + + S   E   +  ++E+
Sbjct: 1673 DYEKQEQQIEEMRVEAKMERKELDQIKKTLKEMEAYLEKEKEEMKSITEETRRQKEDLEK 1732

Query: 407  LQTLMHGEHSNFIQIESALQALQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQ-DFKE 465
            + T ++ +  +       L+  ++  +   K+ +    E    +   K+ +L K+ + KE
Sbjct: 1733 MSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKE 1792

Query: 466  EMQGIVEENKTLHELNFSST-RSLKKQQMEISKLKEIKEKLEREFHTSTEESNVLQRETH 524
            + + + E    + E+   +    +KK++ +  + +E++ K+E E     +  + L+R   
Sbjct: 1793 DRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRS 1852

Query: 525  QIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALRE 584
            ++  + + LN+  + + ++ + L    +      + ++ E   L +  K+   EK  +  
Sbjct: 1853 EMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIEN 1912

Query: 585  KSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQ 621
              + + ++++E    +  +    +ELD  R  + + Q
Sbjct: 1913 SKEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQ 1949


>UniRef100_UPI0000437331 UPI0000437331 UniRef100 entry
          Length = 2003

 Score =  214 bits (544), Expect = 2e-53
 Identities = 361/1780 (20%), Positives = 742/1780 (41%), Gaps = 235/1780 (13%)

Query: 6    ESESRRLYSWWWDSHNSPKNSKWLLENLTDIDTKVKSMIKLIEEEADSFARRAEMYYKKR 65
            E E  +L    ++        + + E   +   K+K  IK IE + D       M  K++
Sbjct: 316  EEEKNKLEQMKFELQREADEIRKIKEETQNERQKIKEKIKAIESDRD-------MLEKEK 368

Query: 66   PELMKLVEEFYRAYRALAERYDHAMGELRHAHKTMPEAFPNSAYYILNDDSPCGSLGPDA 125
             +L K   +  RA   L ++    + E++   + + +   N  + I              
Sbjct: 369  HDLEKTRSKLLRAKENLEKQRKIKLAEIQKEREDLEKM--NEKFTI-------------- 412

Query: 126  ESHTSARPTHRSKKNERSSEESNGEVQTLREALAK----MQSDKDALFLQYQESLENLSK 181
            E H       + K+ +   ++   E+Q L++ L K    +  D+  L L+  E    L K
Sbjct: 413  EIHDIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSE----LDK 468

Query: 182  METDLNKA----QNNARGLDDRASEAEIQVE--------------ILKESLMQLKADKDA 223
             +T++N      +N  + LD    E E Q +               L E L  +K  K  
Sbjct: 469  QQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQV 528

Query: 224  GEVLYNQCLETIARLESMLSQKDNIEAKNLKQELTRVVV---------QKDTVLLQYKQC 274
             E   ++ +E   +++S+ S KD +E +    E TR  +         QK+  L Q ++ 
Sbjct: 529  LEDEKSKDIEK--KIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQKE 586

Query: 275  LEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEERDSLSVLYHHCLEKI 334
             E +  +   I       +   +Q+ + + E++ L+  +  + +E +    +      ++
Sbjct: 587  REDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQL 646

Query: 335  SKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQLEAENLVQRIASKD 394
             + ++E+   Q N   +   ++ E ++L+   K +  +E+  Q ++ E +N+ Q   S D
Sbjct: 647  DRRQSELDKQQTNMNDIMETMKNERKQLD---KDKEEMEEQKQEMEKERDNMDQSRKSLD 703

Query: 395  HELL----------EKHTEIERLQTLMHGEHSNFIQI----ESALQALQKLYSQSQKEQR 440
             +L           E+  ++E+++  +  E  +  +I    ++  Q L+K+  + +KE++
Sbjct: 704  EDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERK 763

Query: 441  NLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHEL--NFSS-TRSLKKQQMEISK 497
            ++A   +        L+  K   +  M  + +E   L E+  N S  T  ++K++ +I  
Sbjct: 764  DVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKIRL 823

Query: 498  LKEIKEKLEREFH-----TSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQSLGLNPN 552
             ++  E+L+ E H     T  E+SN+ +RE   I  D++ L  +  ++    +SL L+  
Sbjct: 824  REDELEQLQAEIHKQQSETEIEKSNI-ERERAAIIKDVEDLQSKIISLDRDAESLKLDRE 882

Query: 553  SFAASVRDLQNENFMLK---ETCKKEHSEKEALREKSKDMNEVLMENACMEFSLLGLNDE 609
            +F     +L+     L+   +  +K   E +  R++ ++M    ME    E   L  N  
Sbjct: 883  AFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLDKNKV 942

Query: 610  LDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESMQKILENNTVLEKSLSDA 669
            +  +    +E+++    + + +  L ++   + +Q Q++ E   K+ +    LE+   + 
Sbjct: 943  M--IEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIGLEREADEI 1000

Query: 670  KIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVEEKLSNLEK-KVTNLEEK 728
                E  + +  +LE     L +E+  L  E          ++ K   L+K KV N E  
Sbjct: 1001 SKIKEETQNERQNLEKMANALKEEREYLAEE----------IKRKNQVLDKIKVAN-EST 1049

Query: 729  YADVEKDKESAVNQVEELFASILVQKENHSNHKHSSEAR---LANLENIVRVLQEEQRLG 785
             AD++K+K      +EE+  +I  Q E+  N K  S+ R   L  L+  V+  Q E  + 
Sbjct: 1050 LADLQKEKRI----LEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDME 1105

Query: 786  KVEFEQELDRVVNAQIEMFI-LQNCIEELELKNFVLLTECEKLVEASKFSDKVISELESE 844
            K   E E   ++  +  M   L+   E++E++   +LTE E L        K + +L+ +
Sbjct: 1106 KTNIESERAAMIREKQNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQK 1165

Query: 845  NLMQLIEEEFLLHRIRKFKMD---IHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIES 901
             +    + E L      F+ +   + ++   LQI +D     EI+K ++       ++E 
Sbjct: 1166 LMSIERDSESLKLDKEAFENEKEAMKQMKTDLQIQAD-----EIEKIKLETHHERQRVEE 1220

Query: 902  LESSLVKSQEENQQLLVE----NSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQNVI 957
              + + K +EE   L+ E      ++  S  + + E E ++ + KT E E   ++ Q   
Sbjct: 1221 KTAQIQKEREEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDSKTRELELIEIQRQKDD 1280

Query: 958  LQKDKVELLEENRQLRI---EVVNGVEKENRSKSTLAALQAEMIELRQTNQVFQEENGKM 1014
            L+    +L  E R L +   E+V   +  ++    +   + EM ++R       EE  + 
Sbjct: 1281 LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANATEEINRE 1340

Query: 1015 LDEKNSLCRNVSD-------LKDAKSSAEDENSVMFHDVLALSNLNLVYEIFFTENMVEK 1067
              E   L  NV         L +  ++ EDE S       A     LV E+     MV +
Sbjct: 1341 RQELEILRNNVQSARHDFELLLERTANLEDEESA------ATDIERLVLEVVKIREMV-R 1393

Query: 1068 RALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIERMDKELLEMDKRLKAAE 1127
                E    +     +  QE   +R+  + ++ E   L + I R +KE +E+ + L  +E
Sbjct: 1394 NLKGEMERRMEKKLEEKQQEEESMREILQKEKEELEQLKKDINR-EKEDIEISRELVESE 1452

Query: 1128 TSNAEFS------RHIEELKMEQEESTKIKENLDR---------QILEQSE-NCMNHKKE 1171
                E        ++ EEL++  EE    K NL++         Q LE+ +   +  K E
Sbjct: 1453 IYEGEVKGFTDVQKYKEELQIVTEELLTKKRNLEQLNSDVQHLMQTLEEVDIQYIKKKAE 1512

Query: 1172 IEHLN----EANETLQFEMKTL------LHEVEQHRVREEALNLELLNKENEFKLWENEA 1221
            +EH+     +  + L+ + K L      + E+E  +V  E++N+E+L K  +    E E 
Sbjct: 1513 LEHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLESINMEILQKREDM---EKEK 1569

Query: 1222 AAFYHDLQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMREIISLLESEIGGLK 1281
                 + Q +     L   +  E+  + +    E      E E +R       SEI   +
Sbjct: 1570 ENLRREKQETE----LFREEEEEIRVIVETERKELYQIKSELERVR-------SEIDHEQ 1618

Query: 1282 EQLSAYVPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVIE-TCLRKHSHQSAREN 1340
            ++L+ Y+ ++   KED   ++  S +  +R  +    ++ D  I+ T L KH  + ++E 
Sbjct: 1619 KKLNDYMKMIEQEKEDLEKMK--SEIMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKEI 1676

Query: 1341 EIVLIPDGVSDLLTLQTRIRAVEKIMMEELKRRVKQKSLTTESTPYSSLEIATYPKVENR 1400
                    V  L+      R   ++  EEL   ++++ +  E     +L +    K++N 
Sbjct: 1677 --------VEKLMVEVEEQRKDIQLQKEELD--IERQKIADEQ----NLLVQNKAKLQNE 1722

Query: 1401 KKEIELVEENVFDRNSWRKKPKIRLLMKDIPLDRNVDDQNSKYLKREHRRTNDHVLELCE 1460
             + I+ V+E +       ++ +I L  +   L   +++   +    E   T+ +  +L  
Sbjct: 1723 NERIKKVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHL 1782

Query: 1461 NNEHEPLSAPT--VDHAM--ICHRSDDSGRYLNYSSELDIEKELGVD------------- 1503
             N+ + L      ++H M  +  R D+    ++   E   ++E+  +             
Sbjct: 1783 KNQRDLLEQEREEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIE 1842

Query: 1504 ---KLELSKSVKEKTEDDKRRILERLSSDGQKLAILKMALQDLKKKTETKKKSKQGNDIE 1560
               K EL + ++EK E+D+  +   +  + ++L  +K  L+ ++ + + ++K    +   
Sbjct: 1843 MKTKAELQEIMQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKI 1902

Query: 1561 YETVKRHIEEVEEAVMQQVSINDQMAKNVEEGASSLDREIPR---------RGSEQIGKL 1611
             E  K  +E+++  +M Q        + +EE  S LD +I +            E + KL
Sbjct: 1903 IEQEKEDLEKMKSEIMTQ-------RQQMEEERSELDNKIKQTDLERHDIENSKEIVQKL 1955

Query: 1612 QFEVQNIQYILLKLAEENNNKVKNRISRKTGILLRRKLRV 1651
              +V+  Q   ++L +E  +  + +I+ + G++++ K ++
Sbjct: 1956 MVKVEE-QRKDIRLQKEELDIERQKIADEQGLVVQNKAKL 1994



 Score =  201 bits (510), Expect = 2e-49
 Identities = 342/1746 (19%), Positives = 723/1746 (40%), Gaps = 219/1746 (12%)

Query: 29   LLENLTDIDTKVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDH 88
            L+E     D  +    + IEE+  S     +M  K++  L K   E Y+    L ++ ++
Sbjct: 118  LIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLEKQKEN 177

Query: 89   AMGELRHAHKTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKNERSSEESN 148
             + E++   + + +   N                   E H       + K+ +   ++  
Sbjct: 178  TLAEIQKEREDLEKMNENIT----------------IEMHEIKHQEEQMKQKQDELDQLK 221

Query: 149  GEVQTLREALAK----MQSDKDALFLQYQESLENLSKMETDLN---KAQNNARGLDDRAS 201
             E+Q L++ L K    +  D+  L L+  E    L K +T++N   +   N R L D+  
Sbjct: 222  TEIQNLQQELEKEKEIIMKDRSELDLRQSE----LDKQQTNMNDIIETMKNERKLLDKDK 277

Query: 202  EAEIQVEILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIEAKNLKQELTRVV 261
            E   ++E  K+ + + + + D      ++ L+ + +L+  + +++  + + +K EL R  
Sbjct: 278  E---EMEEQKQEMEKERDNMDQSIKSLDEDLK-MMKLQKQVIEEEKNKLEQMKFELQREA 333

Query: 262  VQ----KDTVLLQYKQCLEKIPMLENKIALAEENSRML---NDQIERTELEVETLRK-NL 313
             +    K+    + ++  EKI  +E+   + E+    L     ++ R +  +E  RK  L
Sbjct: 334  DEIRKIKEETQNERQKIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENLEKQRKIKL 393

Query: 314  AEMNEERDSLSVLYHHC---LEKISKMENEILHVQENAEQLKNKIEKEAEKL----EISE 366
            AE+ +ER+ L  +       +  I   E ++   Q+  +QLK +I+   ++L    EI  
Sbjct: 394  AEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIM 453

Query: 367  KHRGMLEKSNQNL---QLEAENLVQRIASKDHELLEKHTEIERLQTLMHGEHSNFIQIES 423
            K R  L+     L   Q    ++++ + ++  +L +   E E  +  M  E  +F Q   
Sbjct: 454  KDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRK 513

Query: 424  ALQ---ALQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLH-- 478
            +L     + KL  Q  +++++  +E K     +K ++  K   ++E   + +    L+  
Sbjct: 514  SLDEDLKMMKLQKQVLEDEKSKDIEKK-----IKSIQSDKDMLEKEKHDLEKTRSELYKV 568

Query: 479  --ELNFSSTRSLKKQQMEISKLKEIKEKLEREFHT---STEESNVLQRETHQIKDDIQHL 533
              +L      +L + Q E   L+++ E + RE H      E+ N  Q E  Q+K +IQ+L
Sbjct: 569  KEDLEKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNL 628

Query: 534  NERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEH----SEKEALREKSKDM 589
             +  +   E +       +   + +   Q     + ET K E      +KE + E+ ++M
Sbjct: 629  QQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEM 688

Query: 590  NEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIIT 649
             +   E   M+ S   L+++L       K ++   QV++EEK+ L   K  L  +   I 
Sbjct: 689  EK---ERDNMDQSRKSLDEDL-------KMMKLQKQVIEEEKNKLEQMKIELEREADDIR 738

Query: 650  ESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLE 709
            +  ++      +LEK   + K E +       D+    +    EKN+L   +    S + 
Sbjct: 739  KIKEETQNKRQILEKMAEELKKERK-------DVAHLAEDTKREKNSLDEMKVANESSMA 791

Query: 710  IVEEKLSNLEKKVTNLEEKYADVEKDKES---AVNQVEELFASILVQKENHSNHKHSSEA 766
             ++++ SNLE+   N+ ++  D+EK+K+      +++E+L A I  Q+      K + E 
Sbjct: 792  DLQKEKSNLEEMKENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIER 851

Query: 767  RLANLENIVRVLQ------------------------EEQRLGKVEFEQELDRVVNAQIE 802
              A +   V  LQ                        EE +  K E E+E D +   ++E
Sbjct: 852  ERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLE 911

Query: 803  MFILQNCIEELEL--------------KNFVLLTECEKLVEASKFS-DKVISELESENLM 847
                +  +EE+                KN V++ E ++ +E  +   D+    L+ +  M
Sbjct: 912  TQHERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKM 971

Query: 848  -----QLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESL 902
                 Q++EEE   +++ + K+ + +    +    +    NE +  E   + + ++ E L
Sbjct: 972  MKAQKQVLEEE--KNKLEQMKIGLEREADEISKIKE-ETQNERQNLEKMANALKEEREYL 1028

Query: 903  ESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDK 962
               + +  +   ++ V N   L  LQ+ +   E+++       ++ EN +E++ + + + 
Sbjct: 1029 AEEIKRKNQVLDKIKVANESTLADLQKEKRILEEMRENISKQIEDIENEKEKSKLREDEL 1088

Query: 963  VELLEENRQLRIEVVNGVEKENRSKSTLAAL---QAEMIELRQTNQVFQEENGKMLDEK- 1018
             +L  E ++ + E+   +EK N      A +   Q  M EL++ ++  + +  ++L EK 
Sbjct: 1089 KKLQTEVQKQQSEI--DMEKTNIESERAAMIREKQNMMTELKKKSEDVEMQMKEILTEKE 1146

Query: 1019 ------NSLCRNVSDLKDAKSSAEDENSVMFHDVLALSNLNLVYEIFFTENMVEKRALCE 1072
                  N L ++V DL+    S E ++  +  D  A  N     +   T+  ++   + +
Sbjct: 1147 LLHNDRNLLKKDVEDLQQKLMSIERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEK 1206

Query: 1073 HLGNLSHLNNDLNQEFGVLRKN--------FEVKEAENVYLNESIERMDKELLEMDKRLK 1124
                  H    + ++   ++K          E+K+  ++ ++ES   + KE   ++   K
Sbjct: 1207 IKLETHHERQRVEEKTAQIQKEREEINTLVEEIKKKRDI-IDESYTEIRKEKEAIESDSK 1265

Query: 1125 AAETSNAEFSRHIEELKMEQEESTKIKENLD---RQILEQSENCMNHKKEIEHLNEANET 1181
              E    E  R  ++L+   ++ T  K +L+    +I+ + ++     K++    +  E 
Sbjct: 1266 TRELELIEIQRQKDDLETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEK 1325

Query: 1182 LQFEMKTLLHEVEQHRVREEALNLELLNKENEFKLW--------ENEAAAFYHDLQMSSI 1233
            ++ ++     E+ + R   E L   + +  ++F+L         + E+AA   D++   +
Sbjct: 1326 IRSDIANATEEINRERQELEILRNNVQSARHDFELLLERTANLEDEESAA--TDIERLVL 1383

Query: 1234 CLALLESKVSELTG-VCKILDDESSAKSLENEHMREIISLLESEIGGLKEQLSAYVPLVS 1292
             +  +   V  L G + + ++ +   K  E E MREI+   + E+  LK+        ++
Sbjct: 1384 EVVKIREMVRNLKGEMERRMEKKLEEKQQEEESMREILQKEKEELEQLKKD-------IN 1436

Query: 1293 SLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVIETCLRKHSHQSARENEIVLIPDGVSDL 1352
              KED             R  V     + +V   T ++K+  +     E +L      + 
Sbjct: 1437 REKEDIE---------ISRELVESEIYEGEVKGFTDVQKYKEELQIVTEELLTKKRNLEQ 1487

Query: 1353 LT--LQTRIRAVEKIMMEELKRRVKQKSLTTESTPYSSLEIATYPKVENRKKEIELVEEN 1410
            L   +Q  ++ +E++ ++ +K++ + + +T+E      +       +E +KK++E  E  
Sbjct: 1488 LNSDVQHLMQTLEEVDIQYIKKKAELEHITSEIQKREQI-------LEKQKKKLE--ENG 1538

Query: 1411 VFDRNSWRKKPKIRLLMKDIPLDRNVDDQNSKYLKREHRRTNDHVLELCENNEHEPLSAP 1470
                     K  +  +  +I   R   ++  + L+RE + T     EL    E E     
Sbjct: 1539 WIIEEIEMMKVTLESINMEILQKREDMEKEKENLRREKQET-----ELFREEEEEIRVIV 1593

Query: 1471 TVDHAMICHRSDDSGRYLNYSSELDIEKELGVDKLELSKSVKEKTEDDKRRIL------- 1523
              +   +     +  R     SE+D E++   D +++ +  KE  E  K  I+       
Sbjct: 1594 ETERKELYQIKSELER---VRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQME 1650

Query: 1524 ERLSSDGQKLAILKMALQDLKKKTETKKK-----SKQGNDIEYETVKRHIEEVEEAVMQQ 1578
            E  S    K+    +   D++K  E  +K      +Q  DI+ +  +  IE  + A  Q 
Sbjct: 1651 EERSELDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQN 1710

Query: 1579 VSI-NDQMAKNVEEGASSLDREIPRRGSEQIGKLQFEVQNIQYILLKLAEENNNKVKNRI 1637
            + + N    +N  E    +D EI ++  E + +++  ++  +  L  + EE   + ++  
Sbjct: 1711 LLVQNKAKLQNENERIKKVDEEI-KKERETLREMEIHLKKEKEELRSIIEETQRRKEDLE 1769

Query: 1638 SRKTGI 1643
               T I
Sbjct: 1770 KMSTDI 1775



 Score =  197 bits (500), Expect = 3e-48
 Identities = 332/1620 (20%), Positives = 687/1620 (41%), Gaps = 211/1620 (13%)

Query: 139  KNERSSEESNGEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDD 198
            K +R  E+    +++ R A+ K+  D     +      E+L                LD 
Sbjct: 19   KQQREIEKEKSNIESERAAIIKIVEDLQHKIISLDRDAESLK---------------LDR 63

Query: 199  RASEAEIQVEILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQ--KDNIEAKNLKQE 256
             A E E   E+LK+   +L+ + D  E +  +      R+E M +Q  K+  +  NL +E
Sbjct: 64   EAFENER--EVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQITKERDKINNLIEE 121

Query: 257  LTRVVVQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEM 316
              R    KD VL       EK   +E KI   + +  ML       E E   L K  +E+
Sbjct: 122  TNR----KDMVLN------EKNRDIEEKIKSIQSDKDML-------EKEKHNLEKTRSEL 164

Query: 317  NEERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSN 376
             + ++ L     + L +I K   ++  + EN     ++I+ + E+++  +     L+   
Sbjct: 165  YKVKEDLEKQKENTLAEIQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEI 224

Query: 377  QNLQLEAENLVQRIASKDHELLEKHTEIERLQTLMHGEHSNFIQIESALQALQKLYSQSQ 436
            QNLQ E E   + I     EL  + +E+++ QT       N   I   ++  +KL  + +
Sbjct: 225  QNLQQELEKEKEIIMKDRSELDLRQSELDKQQT-------NMNDIIETMKNERKLLDKDK 277

Query: 437  KEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQ--QME 494
            +E                 +E  KQ+ ++E   + +  K+L E        L+KQ  + E
Sbjct: 278  EE-----------------MEEQKQEMEKERDNMDQSIKSLDE--DLKMMKLQKQVIEEE 318

Query: 495  ISKLKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSF 554
             +KL+++K +L+RE     +     Q E  +IK+ I+ +      + ++   L    +  
Sbjct: 319  KNKLEQMKFELQREADEIRKIKEETQNERQKIKEKIKAIESDRDMLEKEKHDLEKTRSKL 378

Query: 555  AASVRDLQNENFMLKETCKKEHSEKEALREK-SKDMNEVLMENACMEFSLLGLNDELDGL 613
              +  +L+ +  +     +KE  + E + EK + +++++  +   M+       DELD L
Sbjct: 379  LRAKENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQK----QDELDQL 434

Query: 614  RGTVKEIQQFCQVLQEEKSILADEKSTL-LSQLQI------ITESMQKILENNTVLEKSL 666
            +    EIQ   Q L++EK I+  ++S L L Q ++      + + M+ +      L+K  
Sbjct: 435  K---TEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDK 491

Query: 667  SDAKIEFEGLRIKSGD-------LEDCCKLLNDEKNNLQNERSMLI--------SQLEIV 711
             + + + + +  +  D       L++  K++  +K  L++E+S  I        S  +++
Sbjct: 492  EETEEQKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKDIEKKIKSIQSDKDML 551

Query: 712  EEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHSNH----KHSSEAR 767
            E++  +LEK  + L +   D+EK KE+ + Q+++    +    EN +      KH  E  
Sbjct: 552  EKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQM 611

Query: 768  LANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQNCI----------------- 810
                + + ++  E Q L + E E+E + ++ A+ ++   Q+ +                 
Sbjct: 612  NQKQDELDQLKTEIQNL-QQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNE 670

Query: 811  --------EELELKNFVLLTECEKLVEASKFSD---------KVISELESENLMQL-IEE 852
                    EE+E +   +  E + + ++ K  D         K + E E   L Q+ IE 
Sbjct: 671  RKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIEL 730

Query: 853  EFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEE 912
            E     IRK K +      +L+  ++     E+KKE   ++ + +  +  ++SL      
Sbjct: 731  EREADDIRKIKEETQNKRQILEKMAE-----ELKKERKDVAHLAEDTKREKNSL------ 779

Query: 913  NQQLLVENSVLLGSLQQHQSEGEKLK--LEKKT--VEQEFENMREQNVILQKDKVELLEE 968
              ++ V N   +  LQ+ +S  E++K  + K+T  +E+E + +R +   L++ + E+ ++
Sbjct: 780  -DEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQ 838

Query: 969  NRQLRIEVVNGVEKENRS--------KSTLAALQAEMIELRQTNQVFQEENGKMLDEKNS 1020
              +  IE  N +E+E  +        +S + +L  +   L+   + F+ E  ++   K  
Sbjct: 839  QSETEIEKSN-IERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTE 897

Query: 1021 LCRNVSDLKDAKSSAEDEN---SVMFHDVLALSNLNLVYEIFFTENMVE--KRALCEHLG 1075
            L R   +++  K   + E      M  D +   N N   ++   + M+E  K+ + +   
Sbjct: 898  LEREADEIEKIKLETQHERQRVEEMTADFMETMN-NERKQLDKNKVMIEEQKQEMEKKRD 956

Query: 1076 NLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIERMDKELLEMDKRLKAAETSNAEFSR 1135
            ++      L+++  +++   +V E E   L +    +++E  E+ K  +  +       +
Sbjct: 957  DMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIGLEREADEISKIKEETQNERQNLEK 1016

Query: 1136 HIEELKMEQ----EESTKIKENLDRQILEQSENCMNHKKEIEHLNEANETLQFEMKTLLH 1191
                LK E+    EE  +  + LD+  +       + +KE   L E  E +  +++ + +
Sbjct: 1017 MANALKEEREYLAEEIKRKNQVLDKIKVANESTLADLQKEKRILEEMRENISKQIEDIEN 1076

Query: 1192 EVEQHRVREEALNLELLNKENEFKLWENEAAAFYHDLQMSSICLALLESKVSELTGVCKI 1251
            E E+ ++RE+ L      K+ + ++ + ++        + S   A++  K + +T + K 
Sbjct: 1077 EKEKSKLREDEL------KKLQTEVQKQQSEIDMEKTNIESERAAMIREKQNMMTELKKK 1130

Query: 1252 LDD-ESSAKSL--ENEHMREIISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLEHISLLW 1308
             +D E   K +  E E +    +LL+ ++  L+++L +      SLK D  + E+     
Sbjct: 1131 SEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSIERDSESLKLDKEAFENEKEAM 1190

Query: 1309 TKRNSVVGNGAQKDVVIETCLRKHSHQSARENEIVLIPDGVSDLLTLQTRIRAVEKIMME 1368
             +  + +    Q D + +  L  H  +   E +   I     ++ TL   I+    I+ E
Sbjct: 1191 KQMKTDL--QIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEIKKKRDIIDE 1248

Query: 1369 ELKRRVKQKSLTTESTPYSSLEIATYPKVENRKKEIELVEENVFDRNSWRKKPKIRLLMK 1428
                  K+K      +    LE+    +++ +K ++E   + +       +K  + +L  
Sbjct: 1249 SYTEIRKEKEAIESDSKTRELELI---EIQRQKDDLETRIQKL-----TLEKRDLEVLRS 1300

Query: 1429 DIPLDRNVDDQNSKYLKR---EHRRTNDHVLELCE--NNEHEPL-------SAPTVDHAM 1476
            +I L++   DQ  K + R   E  +    +    E  N E + L        +   D  +
Sbjct: 1301 EIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANATEEINRERQELEILRNNVQSARHDFEL 1360

Query: 1477 ICHRSDDSGRYLNYSSELDIEKELGVDKLELSKSVKEKTEDDKRRILERLSSDGQKLAIL 1536
            +  R+  +      S+  DIE+ L ++ +++ + V+    + +RR+ ++L    Q+   +
Sbjct: 1361 LLERT--ANLEDEESAATDIER-LVLEVVKIREMVRNLKGEMERRMEKKLEEKQQEEESM 1417

Query: 1537 KMALQDLKKKTETKKK----SKQGNDIEYETVKRHIEEVEEAVMQQVSINDQMAKNVEEG 1592
            +  LQ  K++ E  KK     K+  +I  E V+  I E E      V    +  + V E 
Sbjct: 1418 REILQKEKEELEQLKKDINREKEDIEISRELVESEIYEGEVKGFTDVQKYKEELQIVTEE 1477

Query: 1593 ASSLDREIPRRGSEQIGKLQ-FEVQNIQYILLKLAEENNNKVKNRISRKTGILLRRKLRV 1651
              +  R + +  S+    +Q  E  +IQYI  K   E+   + + I ++  IL ++K ++
Sbjct: 1478 LLTKKRNLEQLNSDVQHLMQTLEEVDIQYIKKKAELEH---ITSEIQKREQILEKQKKKL 1534



 Score =  182 bits (462), Expect = 8e-44
 Identities = 315/1503 (20%), Positives = 641/1503 (41%), Gaps = 191/1503 (12%)

Query: 141  ERSSEESNGEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDDRA 200
            E+  E +  ++Q  RE L KM  +      + +   E +++ + +L++ +   + L    
Sbjct: 573  EKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQ-- 630

Query: 201  SEAEIQVEILKESLMQL---KADKDAGEVLYNQCLETIARLESMLSQKDNIEAKNLKQEL 257
             E E + EI+ ++  QL   +++ D  +   N  +ET+      L  KD  E +  KQE+
Sbjct: 631  -ELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLD-KDKEEMEEQKQEM 688

Query: 258  TRVVVQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMN 317
             +   ++D +    K   E + M++ +  + EE      +++E+ ++E+E    ++ ++ 
Sbjct: 689  EK---ERDNMDQSRKSLDEDLKMMKLQKQVIEEEK----NKLEQMKIELEREADDIRKIK 741

Query: 318  EERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEIS----EKHRGMLE 373
            EE  +   +     E++ K   ++ H+ E+ ++ KN +++     E S    +K +  LE
Sbjct: 742  EETQNKRQILEKMAEELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLE 801

Query: 374  KSNQNLQLEAENLVQ---RIASKDHELLEKHTEIERLQTLMHGEHSNFIQIESAL----Q 426
            +  +N+  + E++ +   +I  ++ EL +   EI + Q+    E SN  +  +A+    +
Sbjct: 802  EMKENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVE 861

Query: 427  ALQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVE-ENKTLHE------ 479
             LQ       ++  +L L+ +      ++L+  K + + E   I + + +T HE      
Sbjct: 862  DLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEE 921

Query: 480  --LNFSSTRSLKKQQMEISK--LKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNE 535
               +F  T + +++Q++ +K  ++E K+++E++     +    L  +   +K   Q L E
Sbjct: 922  MTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEE 981

Query: 536  RYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDMNEVLME 595
                + +    L    +  +    + QNE   L++       E+E L E+ K  N+VL +
Sbjct: 982  EKNKLEQMKIGLEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDK 1041

Query: 596  -NACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTL----LSQLQIITE 650
                 E +L  L  E   L    + I +  + ++ EK     EKS L    L +LQ   +
Sbjct: 1042 IKVANESTLADLQKEKRILEEMRENISKQIEDIENEK-----EKSKLREDELKKLQTEVQ 1096

Query: 651  SMQKILENNTVLEKSLSDAKIE-----FEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLI 705
              Q  ++      +S   A I         L+ KS D+E   K +  EK  L N+R++L 
Sbjct: 1097 KQQSEIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLK 1156

Query: 706  SQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHSNHK---H 762
              +E +++KL ++E+   +L+      E +KE+    ++++   + +Q +     K   H
Sbjct: 1157 KDVEDLQQKLMSIERDSESLKLDKEAFENEKEA----MKQMKTDLQIQADEIEKIKLETH 1212

Query: 763  SSEARLANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQNCIEELELKNFVLLT 822
                R+      ++  +EE      E +++ D +  +  E+   +  IE  + K   L  
Sbjct: 1213 HERQRVEEKTAQIQKEREEINTLVEEIKKKRDIIDESYTEIRKEKEAIES-DSKTREL-- 1269

Query: 823  ECEKLVEASKFSDKVISELESENL----MQLIEEEFLLHRI---RKFKMDIHKVCGVLQI 875
               +L+E  +  D + + ++   L    ++++  E +L +    +K K  I K   + +I
Sbjct: 1270 ---ELIEIQRQKDDLETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKI 1326

Query: 876  DSD-GGGDNEIKKEEIPISRILDKIES--------LESSLVKSQEENQQLLVENSVL--- 923
             SD      EI +E   +  + + ++S        LE +     EE+    +E  VL   
Sbjct: 1327 RSDIANATEEINRERQELEILRNNVQSARHDFELLLERTANLEDEESAATDIERLVLEVV 1386

Query: 924  -----LGSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVN 978
                 + +L+       + KLE+K  +QE E+MRE   ILQK+K EL     QL+ ++  
Sbjct: 1387 KIREMVRNLKGEMERRMEKKLEEK--QQEEESMRE---ILQKEKEEL----EQLKKDI-- 1435

Query: 979  GVEKENRSKSTLAALQAEMIELRQTNQVFQEENGKMLDE---KNSLCRNVSDLKDAKSSA 1035
                 NR K  +  +  E++E    +++++ E     D    K  L     +L   K + 
Sbjct: 1436 -----NREKEDIE-ISRELVE----SEIYEGEVKGFTDVQKYKEELQIVTEELLTKKRNL 1485

Query: 1036 EDENSVMFHDVLALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNF 1095
            E  NS + H +  L  +++ Y        ++K+A       L H+ +++ +   +L K  
Sbjct: 1486 EQLNSDVQHLMQTLEEVDIQY--------IKKKA------ELEHITSEIQKREQILEKQ- 1530

Query: 1096 EVKEAENVYLNESIERMD-------------KELLEMDKRLKAAETSNAEFSRHIEE--- 1139
            + K  EN ++ E IE M              +E +E +K     E    E  R  EE   
Sbjct: 1531 KKKLEENGWIIEEIEMMKVTLESINMEILQKREDMEKEKENLRREKQETELFREEEEEIR 1590

Query: 1140 --LKMEQEESTKIKENLDR---QILEQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVE 1194
              ++ E++E  +IK  L+R   +I  + +   ++ K IE   E  E ++ E+     ++E
Sbjct: 1591 VIVETERKELYQIKSELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQME 1650

Query: 1195 QHRV----REEALNLELLNKENEFKLWEN---EAAAFYHDLQMSSICLALLESKVSE--- 1244
            + R     + +  NLE  + E   ++ E    E      D+Q+    L +   K+++   
Sbjct: 1651 EERSELDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQN 1710

Query: 1245 --LTGVCKILDDESSAKSLENEHMREIISLLESEIG--GLKEQLSAYVPLVSSLKEDFNS 1300
              +    K+ ++    K ++ E  +E  +L E EI     KE+L + +      KED   
Sbjct: 1711 LLVQNKAKLQNENERIKKVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKED--- 1767

Query: 1301 LEHISLLWTKRNSVVGNGAQKDVVIETCLRKHSHQSARENEIVLIPDGVSDLLTLQTRIR 1360
            LE +S    ++   + N  Q+D+ +E    + +H+  +  + +       D    + R  
Sbjct: 1768 LEKMSTDINEQKLHLKN--QRDL-LEQEREEINHEMTQLQQRI----DEFDAQVSKQRED 1820

Query: 1361 AVEKIMMEELKRRVKQKSLTTESTPYSSLEIATYPKVENRKKEIELVEE------NVFDR 1414
              ++ M EE K   + K+   E    + L+     K E  ++E+ ++ E      N    
Sbjct: 1821 LTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRVIVEMEREELNQIKS 1880

Query: 1415 NSWRKKPKIRLLMKDIPLDRNVDDQNSKYLKR-------------EHRRTNDHVLELCEN 1461
               R + +I    K +  D+ + +Q  + L++             E R   D+ ++  + 
Sbjct: 1881 ELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDL 1940

Query: 1462 NEHEPLSAPTVDHAMICHRSDDSGRYLNYSSELDIEKELGVDKLELSKSVKEKTEDDKRR 1521
              H+  ++  +   ++    +          ELDIE++   D+  L    K K +++  R
Sbjct: 1941 ERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENER 2000

Query: 1522 ILE 1524
            I E
Sbjct: 2001 IKE 2003



 Score =  169 bits (427), Expect = 9e-40
 Identities = 270/1486 (18%), Positives = 614/1486 (41%), Gaps = 211/1486 (14%)

Query: 290  ENSRMLNDQIERTELEVETLRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHVQENAE 349
            EN R+  D++ + + E+    K   E+ +E+ ++       ++ +  ++++I+ +  +AE
Sbjct: 1    ENLRLREDELGQLQAEIH---KQQREIEKEKSNIESERAAIIKIVEDLQHKIISLDRDAE 57

Query: 350  -----------------QLKNKIEKEA---EKLEISEKH-RGMLEKSNQNLQLEAE---N 385
                             Q+K ++E+E    EK+++  +H R  +E+    +  E +   N
Sbjct: 58   SLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQITKERDKINN 117

Query: 386  LVQRIASKDHELLEKHTEIERL-------QTLMHGEHSNF---------------IQIES 423
            L++    KD  L EK+ +IE         + ++  E  N                 Q E+
Sbjct: 118  LIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLEKQKEN 177

Query: 424  ALQALQKLYSQSQKEQRNLAL---ELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHEL 480
             L  +QK     +K   N+ +   E+K+    +K  +      K E+Q + +E +   E+
Sbjct: 178  TLAEIQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEI 237

Query: 481  NFSSTRSLKKQQMEISK-----------LKEIKEKLEREFHTSTEESNVLQRETHQIKDD 529
                   L  +Q E+ K           +K  ++ L+++     E+   +++E   +   
Sbjct: 238  IMKDRSELDLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQKQEMEKERDNMDQS 297

Query: 530  IQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDM 589
            I+ L+E  + M  Q Q +    N       +LQ E   +++  ++  +E++ ++EK K  
Sbjct: 298  IKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQNERQKIKEKIK-- 355

Query: 590  NEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIIT 649
                            +  + D L     ++++    L   K  L  ++   L+++Q   
Sbjct: 356  ---------------AIESDRDMLEKEKHDLEKTRSKLLRAKENLEKQRKIKLAEIQKER 400

Query: 650  ESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLE 709
            E ++K+ E  T+    + D K + E ++ K  +L+     + + +  L+ E+ +++    
Sbjct: 401  EDLEKMNEKFTI---EIHDIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRS 457

Query: 710  IVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHSNHKHSSEARLA 769
             ++ + S L+K+ TN+ +    ++ +++      EE       QK+     KH  +    
Sbjct: 458  QLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEE----QKQEMEKEKHDFDQSRK 513

Query: 770  NLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQNCIEELELKNFVLLTECEKLVE 829
            +L+  +++++ ++++  +E E+  D           ++  I+ ++    +L  E   L +
Sbjct: 514  SLDEDLKMMKLQKQV--LEDEKSKD-----------IEKKIKSIQSDKDMLEKEKHDLEK 560

Query: 830  ASKFSDKVISELESENLMQLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEE 889
                  KV  +LE        ++E  L +I+K + D+ K+   +  +      +EIK +E
Sbjct: 561  TRSELYKVKEDLEK-------QKENTLAQIQKEREDLEKMNENITREM-----HEIKHQE 608

Query: 890  IPISRILDKIESLESSLVKSQEENQQLLVENSVLL---GSLQQHQSEGEKLKLEKKTVEQ 946
              +++  D+++ L++ +   Q   Q+L  E  +++     L + QSE +K +     + +
Sbjct: 609  EQMNQKQDELDQLKTEI---QNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIME 665

Query: 947  EFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKENRSKSTLAALQAEMIELRQTNQV 1006
              +N R+Q   L KDK E+ E+ +++        E++N  +S   +L  ++  ++   QV
Sbjct: 666  TMKNERKQ---LDKDKEEMEEQKQEME------KERDNMDQSR-KSLDEDLKMMKLQKQV 715

Query: 1007 FQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVM---------------------FHD 1045
             +EE  K+   K  L R   D++  K   +++  ++                       +
Sbjct: 716  IEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAEDTKRE 775

Query: 1046 VLALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLR-KNFEVKEAE-NV 1103
              +L  + +  E    +   EK  L E   N+S    D+ +E   +R +  E+++ +  +
Sbjct: 776  KNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLREDELEQLQAEI 835

Query: 1104 YLNESIERMDKELLEMD-----KRLKAAETSNAEFSRHIEELKM-------EQEESTKIK 1151
            +  +S   ++K  +E +     K ++  ++      R  E LK+       E+EE  ++K
Sbjct: 836  HKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMK 895

Query: 1152 ENLDRQILEQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLELLNKE 1211
              L+R+  E  +  +  + E + + E        M     ++++++V  E    E+  K 
Sbjct: 896  TELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKR 955

Query: 1212 NEFKLWENEAAAFYHDLQMSSICLALLESKVSEL----TGVCKILDDESSAK---SLENE 1264
            ++    +    +   DL+M      +LE + ++L     G+ +  D+ S  K     E +
Sbjct: 956  DDM---DQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIGLEREADEISKIKEETQNERQ 1012

Query: 1265 HMREIISLLESEIGGLKEQLS-----------AYVPLVSSLKEDFNSLEHISLLWTKRNS 1313
            ++ ++ + L+ E   L E++            A    ++ L+++   LE +    +K+  
Sbjct: 1013 NLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLADLQKEKRILEEMRENISKQIE 1072

Query: 1314 VVGNGAQKDVVIETCLRK-HSHQSARENEIVLIPDGVSDLLTLQTRIRAVEKIMMEELKR 1372
             + N  +K  + E  L+K  +    +++EI +    +        R    ++ MM ELK+
Sbjct: 1073 DIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAAMIR---EKQNMMTELKK 1129

Query: 1373 R-----VKQKSLTTESTPYSSLEIATYPKVENRKKEIELVEEN----VFDRNSWRKKPKI 1423
            +     ++ K + TE     +        VE+ ++++  +E +      D+ ++  + + 
Sbjct: 1130 KSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSIERDSESLKLDKEAFENEKE- 1188

Query: 1424 RLLMKDIPLDRNVDDQNSKYLKREHRRTNDHVLELCENNEHEPLSAPTVDHAMICHRSDD 1483
               MK +  D  +     + +K E       V E     + E     T+   +   R   
Sbjct: 1189 --AMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEIKKKRDII 1246

Query: 1484 SGRYLNYSSELD-IEKELGVDKLELSKSVKEKTEDDKRRILERLSSDGQKLAILKMALQD 1542
               Y     E + IE +    +LEL +  ++K  DD    +++L+ + + L +L+  +  
Sbjct: 1247 DESYTEIRKEKEAIESDSKTRELELIEIQRQK--DDLETRIQKLTLEKRDLEVLRSEIVL 1304

Query: 1543 LKKKTETKKKSKQGNDIEYETVKRHIEEVEEAVMQQVSINDQMAKNVEEGASSLDREIPR 1602
             KK  + K K       E E ++  I    E + ++    + +  NV+      +  + R
Sbjct: 1305 EKKDLDQKMKQVIRKRDEMEKIRSDIANATEEINRERQELEILRNNVQSARHDFELLLER 1364

Query: 1603 --------RGSEQIGKLQFEVQNIQYILLKLAEENNNKVKNRISRK 1640
                      +  I +L  EV  I+ ++  L  E   +++ ++  K
Sbjct: 1365 TANLEDEESAATDIERLVLEVVKIREMVRNLKGEMERRMEKKLEEK 1410



 Score =  140 bits (352), Expect = 4e-31
 Identities = 237/1088 (21%), Positives = 472/1088 (42%), Gaps = 135/1088 (12%)

Query: 33   LTDIDTKVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAE---RYDHA 89
            L +   K++ M   +E EAD  ++  E    +R  L K+          LAE   R +  
Sbjct: 979  LEEEKNKLEQMKIGLEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQV 1038

Query: 90   MGELRHAHKTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKNERSSEESNG 149
            + +++ A+++           +            D E+        +SK  E   ++   
Sbjct: 1039 LDKIKVANESTLADLQKEKRILEEMRENISKQIEDIENEKE-----KSKLREDELKKLQT 1093

Query: 150  EVQTLREAL----AKMQSDKDALFLQYQESLENLSK----METDLNKAQNNARGLDDRAS 201
            EVQ  +  +      ++S++ A+  + Q  +  L K    +E  + +       L +  +
Sbjct: 1094 EVQKQQSEIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEMQMKEILTEKELLHNDRN 1153

Query: 202  EAEIQVEILKESLMQLKADKDAGEV---LYNQCLETIARLESMLS-QKDNIEAKNLKQEL 257
              +  VE L++ LM ++ D ++ ++    +    E + ++++ L  Q D IE   L+   
Sbjct: 1154 LLKKDVEDLQQKLMSIERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHH 1213

Query: 258  TRVVVQKDTVLLQYKQCLEKIPMLENKIA----LAEENSRMLNDQIERTELEVETLRKNL 313
             R  V++ T  +Q ++  E+I  L  +I     + +E+   +  + E  E + +T    L
Sbjct: 1214 ERQRVEEKTAQIQKER--EEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDSKTRELEL 1271

Query: 314  AEMNEERDSLSV-LYHHCLEK--ISKMENEILHVQENAEQ-LKNKIEKEAEKLEISEKHR 369
             E+  ++D L   +    LEK  +  + +EI+  +++ +Q +K  I K  E  +I     
Sbjct: 1272 IEIQRQKDDLETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIA 1331

Query: 370  GMLEKSNQNLQLEAENLVQRIASKDHE---LLEKHTEIERLQTLMHGEHSNFIQIESALQ 426
               E+ N+  Q E E L   + S  H+   LLE+   +E        E S    IE  + 
Sbjct: 1332 NATEEINRERQ-ELEILRNNVQSARHDFELLLERTANLE-------DEESAATDIERLVL 1383

Query: 427  ALQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKT-LHELNFSST 485
             + K+    ++  RNL  E++  +   K LE  KQ  +E M+ I+++ K  L +L     
Sbjct: 1384 EVVKI----REMVRNLKGEMERRME--KKLE-EKQQEEESMREILQKEKEELEQLKKDIN 1436

Query: 486  RSLKKQQMEISKLK--------EIK-----EKLEREFHTSTEESNVLQRETHQIKDDIQH 532
            R  +K+ +EIS+          E+K     +K + E    TEE    +R   Q+  D+QH
Sbjct: 1437 R--EKEDIEISRELVESEIYEGEVKGFTDVQKYKEELQIVTEELLTKKRNLEQLNSDVQH 1494

Query: 533  LNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDMNEV 592
            L       ++ L+ + +      A +  + +E        +K     E  ++K ++   +
Sbjct: 1495 L-------MQTLEEVDIQYIKKKAELEHITSE-------IQKREQILEKQKKKLEENGWI 1540

Query: 593  LMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESM 652
            + E   M+ +L  +N E+   R  +++ ++  +  ++E  +  +E+     ++++I E+ 
Sbjct: 1541 IEEIEMMKVTLESINMEILQKREDMEKEKENLRREKQETELFREEEE----EIRVIVETE 1596

Query: 653  QKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVE 712
            +K L     ++  L   + E +  + K   L D  K++  EK +L+  +S ++ Q + +E
Sbjct: 1597 RKELYQ---IKSELERVRSEIDHEQKK---LNDYMKMIEQEKEDLEKMKSEIMKQRQQME 1650

Query: 713  EKLSNLEKKV--TNLEEKYADVEKDKE---SAVNQVEELFASILVQKE--NHSNHKHSSE 765
            E+ S L+ K+  TNLE+   D+EK KE     + +VEE    I +QKE  +    K + E
Sbjct: 1651 EERSELDNKIQQTNLEKH--DIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADE 1708

Query: 766  ARLANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQNCIEELELKNFVLLTECE 825
              L  ++N  ++  E +R+ KV+ E + +R    ++E+ + +   E+ EL++ +  T+  
Sbjct: 1709 QNLL-VQNKAKLQNENERIKKVDEEIKKERETLREMEIHLKK---EKEELRSIIEETQRR 1764

Query: 826  KLVEASKFSDKVISELESENLMQLIEEEF---------LLHRIRKFKMDIHKVCGVLQID 876
            K       +D    +L  +N   L+E+E          L  RI +F   + K    L   
Sbjct: 1765 KEDLEKMSTDINEQKLHLKNQRDLLEQEREEINHEMTQLQQRIDEFDAQVSKQREDLTKQ 1824

Query: 877  SDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSVLLGSLQQHQSE--- 933
                    +++ +  I  +  K E  E    K +E+ +++ V   +    L Q +SE   
Sbjct: 1825 EMEEERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRVIVEMEREELNQIKSELKR 1884

Query: 934  --------GEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKENR 985
                     +KL  +KK +EQE E+       L+K K E++ + +Q+  E     E +N+
Sbjct: 1885 VRSEIDHEQKKLNDDKKIIEQEKED-------LEKMKSEIMTQRQQMEEE---RSELDNK 1934

Query: 986  SKSTLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHD 1045
             K T      E  ++  + ++ Q+   K+ +++  +     +L   +    DE  ++  +
Sbjct: 1935 IKQT----DLERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQGLVVQN 1990

Query: 1046 VLALSNLN 1053
               L N N
Sbjct: 1991 KAKLQNEN 1998



 Score =  133 bits (334), Expect = 5e-29
 Identities = 208/1016 (20%), Positives = 435/1016 (42%), Gaps = 141/1016 (13%)

Query: 674  EGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVE 733
            E LR++  +L      ++ ++  ++ E+S + S+   + + + +L+ K+ +L+     ++
Sbjct: 1    ENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHKIISLDRDAESLK 60

Query: 734  KDKESAVNQVEELFASILVQKENHSNHKHSSEARLANLENIVRVLQEEQRLGKVEFEQEL 793
             D+E+  N+ E L              K   E     +E I           K+E + + 
Sbjct: 61   LDREAFENEREVL-----------KQMKTELERETDEIEKI-----------KLETQHDR 98

Query: 794  DRV--VNAQI--EMFILQNCIEELELKNFVLLTECEKLVEASKF--SDKVISELESENLM 847
             RV  + AQI  E   + N IEE   K+ VL  +   + E  K   SDK + E E  NL 
Sbjct: 99   QRVEEMTAQITKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLE 158

Query: 848  QLIEE------------EFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPISRI 895
            +   E            E  L  I+K + D+ K+   + I+      +EIK +E  + + 
Sbjct: 159  KTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITIEM-----HEIKHQEEQMKQK 213

Query: 896  LDKIESLESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQN 955
             D+++ L++ +   Q   Q+L  E  +++    +      +L  ++  +    E M+ + 
Sbjct: 214  QDELDQLKTEI---QNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNER 270

Query: 956  VILQKDKVELLEENRQLRIEVVNGVEKENRSKSTLAALQAEMIELRQTNQVFQEENGKML 1015
             +L KDK E+ E+ +++        E++N  +S + +L  ++  ++   QV +EE  K+ 
Sbjct: 271  KLLDKDKEEMEEQKQEME------KERDNMDQS-IKSLDEDLKMMKLQKQVIEEEKNKLE 323

Query: 1016 DEKNSLCRNVSDLKDAKSSAEDENSVMFHDVLALSNLNLVYEIFFTENMVEKRALCEHLG 1075
              K  L R   +++  K   ++E   +   + A+ +           +M+EK    +H  
Sbjct: 324  QMKFELQREADEIRKIKEETQNERQKIKEKIKAIES---------DRDMLEKE---KH-- 369

Query: 1076 NLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIERMDKELLEMDKRLKAAETSNAEFSR 1135
            +L    + L +    L K  ++K AE     E +E+M+++       +K  E    +   
Sbjct: 370  DLEKTRSKLLRAKENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQD 429

Query: 1136 HIEELKME----QEESTKIKENL--DRQILEQSENCMNHKKEIEHLNEANETLQFEMKTL 1189
             +++LK E    Q+E  K KE +  DR  L+  ++ ++  K+  ++N+  ET++ E K L
Sbjct: 430  ELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELD--KQQTNVNDIMETMKNERKQL 487

Query: 1190 LHEVEQHRVREEALNLELLNKENEFKLWENEAAAFYHDLQMSSICLALLE-SKVSELTGV 1248
              + E+   +++ +       E E   ++    +   DL+M  +   +LE  K  ++   
Sbjct: 488  DKDKEETEEQKQEM-------EKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKDIEKK 540

Query: 1249 CKILDDESSAKSLENEHMREIISLLESEIGGLKEQLSAYVPLVSSLKEDFNSL-EHIS-- 1305
             K +  +      E   + +  S L      L++Q    +  +   +ED   + E+I+  
Sbjct: 541  IKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITRE 600

Query: 1306 LLWTKRNSVVGNGAQKDV-VIETCLRKHSHQSARENEIVL-----IPDGVSDLLTLQTRI 1359
            +   K      N  Q ++  ++T ++    +  +E EI++     +    S+L   QT +
Sbjct: 601  MHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNM 660

Query: 1360 RAVEKIMMEELKRRVKQKSLTTESTPYSSLEIATYPKVENRKKEIELVEENV-FDRNSWR 1418
              + + M  E K+  K K                  ++E +K+E+E   +N+   R S  
Sbjct: 661  NDIMETMKNERKQLDKDKE-----------------EMEEQKQEMEKERDNMDQSRKSLD 703

Query: 1419 KKPKIRLLMKDIPLDRNVDDQNSK--YLKREHRRTNDHVLELCENNEH---------EPL 1467
            +  K+  L K +     ++++ +K   +K E  R  D + ++ E  ++         E L
Sbjct: 704  EDLKMMKLQKQV-----IEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEEL 758

Query: 1468 SAPTVDHAMICHRSDDSGRYLNYSSELDIEKELGVDKLELSKSVKEKTEDDKRRILERLS 1527
                 D   + H ++D+ R  N   E+ +  E  +  L+  KS  E+ +++  +  E + 
Sbjct: 759  KKERKD---VAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIE 815

Query: 1528 SDGQKLAILKMALQDLKKKTETKKKSKQGNDIEYETVKRHIEEVEEAVMQQVSINDQMAK 1587
             +  K+ + +  L+ L+ +       KQ ++ E E  K +IE    A+++ V        
Sbjct: 816  KEKDKIRLREDELEQLQAEIH-----KQQSETEIE--KSNIERERAAIIKDVEDLQSKII 868

Query: 1588 NVEEGASS--LDREIPRRGSEQIGKLQFEVQNIQYILLKLAEENNNKVKNRISRKT 1641
            +++  A S  LDRE      E++ +++ E++     + K+  E  ++ + R+   T
Sbjct: 869  SLDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHE-RQRVEEMT 923



 Score = 89.7 bits (221), Expect = 7e-16
 Identities = 111/614 (18%), Positives = 268/614 (43%), Gaps = 60/614 (9%)

Query: 138  KKNERSSEESNGEVQTLREALAKMQSDKDALFLQYQESLENLS---------------KM 182
            ++ E+  EE   E +++RE L K + + + L        E++                K 
Sbjct: 1401 RRMEKKLEEKQQEEESMREILQKEKEELEQLKKDINREKEDIEISRELVESEIYEGEVKG 1460

Query: 183  ETDLNKAQNNARGLDDRASEAEIQVEILKESLMQLKADKDAGEVLYNQCLETIARLESML 242
             TD+ K +   + + +     +  +E L   +  L    +  ++ Y +    +  + S +
Sbjct: 1461 FTDVQKYKEELQIVTEELLTKKRNLEQLNSDVQHLMQTLEEVDIQYIKKKAELEHITSEI 1520

Query: 243  SQKDNIEAKNLK---------QELTRVVVQKDTVLLQYKQCLEKIPMLENKIALAEENSR 293
             +++ I  K  K         +E+  + V  +++ ++  Q  E +   +  +   ++ + 
Sbjct: 1521 QKREQILEKQKKKLEENGWIIEEIEMMKVTLESINMEILQKREDMEKEKENLRREKQETE 1580

Query: 294  MLNDQIERTELEVETLRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHVQENAEQLKN 353
            +  ++ E   + VET RK L ++  E + +     H  +K++     I   +E+ E++K+
Sbjct: 1581 LFREEEEEIRVIVETERKELYQIKSELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKS 1640

Query: 354  KIEKEAEKLEISEKHRGMLEKSNQNLQLEAENLVQRIASKDHELLEK---HTEIERLQTL 410
            +I K+ +++E         E+S  + +++  NL +    K  E++EK     E +R    
Sbjct: 1641 EIMKQRQQMEE--------ERSELDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQ 1692

Query: 411  MHGEHSNF----IQIESALQALQKLYSQSQKEQ-RNLALELKYGLLLLKDLELSKQDFKE 465
            +  E  +     I  E  L    K   Q++ E+ + +  E+K     L+++E+  +  KE
Sbjct: 1693 LQKEELDIERQKIADEQNLLVQNKAKLQNENERIKKVDEEIKKERETLREMEIHLKKEKE 1752

Query: 466  EMQGIVEENKTLHELNFSSTRSLKKQQMEISKLKEIKEKLEREFHTSTEESNVLQRETHQ 525
            E++ I+EE +   E     +  + +Q++    LK  ++ LE+E      E   LQ+   +
Sbjct: 1753 ELRSIIEETQRRKEDLEKMSTDINEQKLH---LKNQRDLLEQEREEINHEMTQLQQRIDE 1809

Query: 526  IKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALRE- 584
               D Q   +R     ++++    +     A + +++ +  + +   +KE  ++E +R  
Sbjct: 1810 F--DAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRVI 1867

Query: 585  ---KSKDMNEVLME----NACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADE 637
               + +++N++  E     + ++     LND+   +    +++++    +  ++  + +E
Sbjct: 1868 VEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEE 1927

Query: 638  KSTLLSQLQII------TESMQKILENNTV-LEKSLSDAKIEFEGLRIKSGDLEDCCKLL 690
            +S L ++++         E+ ++I++   V +E+   D +++ E L I+   + D   L+
Sbjct: 1928 RSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQGLV 1987

Query: 691  NDEKNNLQNERSML 704
               K  LQNE   +
Sbjct: 1988 VQNKAKLQNENERI 2001


>UniRef100_UPI0000437335 UPI0000437335 UniRef100 entry
          Length = 1880

 Score =  211 bits (538), Expect = 1e-52
 Identities = 332/1675 (19%), Positives = 706/1675 (41%), Gaps = 144/1675 (8%)

Query: 39   KVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHAMGELRHAHK 98
            K++ M   +E+EAD   +  E    +R  L K+ EE  +   +     +    E +   K
Sbjct: 213  KLEQMKIELEKEADEIRKIKEETQNERQRLEKMTEELKKEKESFTHLAEDTKTEKKILDK 272

Query: 99   TMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKNERSSE--------ESNGE 150
             M  A  +    +  + S    +  +    T      + K   R  E            E
Sbjct: 273  -MKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLREDELEQLQAEIHKQQE 331

Query: 151  VQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDDRASEAEIQVEIL 210
            +Q  RE L KM           +   E + + + +L++ +   + L     E E + EI+
Sbjct: 332  IQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQQ---ELEKEKEII 388

Query: 211  KESLMQL---KADKDAGEVLYNQCLETIARLESMLSQKDNIEAKNLKQELTRVVVQKDTV 267
             +   QL   +++ D  +   N  +ET+      L  KD  E +  KQE+ +   +K   
Sbjct: 389  MKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLD-KDKEETEEQKQEMEK---EKHDF 444

Query: 268  LLQYKQCLEKIPM--LENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEERDSLSV 325
                K  +EKI +    ++  + E  +++  D+ E   L  ET RK++    + RD    
Sbjct: 445  DQSRKNEIEKIKLETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIEEK 504

Query: 326  LYHHCLEK--ISKMENEILHVQENAEQLKNKIEKEAEK-LEISEKHRGMLEKSNQNLQLE 382
            +     +K  + K ++++   +    ++K  +EK+ E  L   +K R  LEK N+N+  E
Sbjct: 505  IKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITRE 564

Query: 383  AENLV---QRIASKDHELLEKHTEIERLQTLMHGEHSNFIQIESALQALQKLYSQSQKEQ 439
               +    +++  K  EL +  TEI+ LQ  +  E    ++  S L   Q   S+  K+Q
Sbjct: 565  MHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQ---SELDKQQ 621

Query: 440  RNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEISKLK 499
             N+   ++      K L+  K++ +E+ Q + +E   + +   S     KK +++    +
Sbjct: 622  TNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFE 681

Query: 500  EIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVR 559
            E K KLE+       E++    E  +IK++ Q  N+R + + E+++S+  + +       
Sbjct: 682  EEKNKLEQMKIELEREAD----EISKIKEETQ--NKRQRDIEEKIKSIQSDKDMLEKERH 735

Query: 560  DLQ---NENFMLKETCKKEHSEKEALREKSKDMNEVLMENACMEFSLLG-----LNDELD 611
            +L+   +E + +KE  +K+     A  +K ++  E + EN   E   +      +N + D
Sbjct: 736  NLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQD 795

Query: 612  GLRGTVKEIQQFCQVLQEEKSILADEKSTL---LSQLQIITESMQKILENNTVLEKSLSD 668
             L     EIQ   Q L++EK I+  ++S      S+L     +M  I+E      K L  
Sbjct: 796  ELDQLKTEIQNLQQELEKEKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDK 855

Query: 669  AKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEEK 728
             K E E    +  ++E      +  + +L  +  M+  Q ++ EE+ + LE+    LE +
Sbjct: 856  DKEEMEE---QKQEMEKEKHDFDQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELERE 912

Query: 729  YADVEKDKESAVNQVEELFASILVQKENHSNHKHSSEARLANLENIVRV-LQEEQRLGKV 787
              ++ K KE   N+ + L       K+   +  H +E      E + +V +  E  +  +
Sbjct: 913  ADEIRKIKEETQNERQSLEKMTEELKKEKESFTHLAEDTKKEQEILDKVKVANESLMADL 972

Query: 788  EFE----QELDRVVNAQIEMFILQNCIEELELKNFVLLTECEKLVEASKFSDKVISELES 843
            + E    +E+   ++ Q E   ++N  E L L+   L     ++ +  +  +K    +ES
Sbjct: 973  QKEKSNLEEMRENISKQTED--VENKKENLRLREDELWQLQAEIYKQQREIEKEKINIES 1030

Query: 844  ENLMQLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNE---IKKEEIPISRILDKIE 900
            E    +   E L H+I     D       L++D +   +NE   +K+ +  + R  D+IE
Sbjct: 1031 ERAAIIKNVEDLQHKIISLDRDSES----LKLDREAF-ENEREVLKQMKTELEREADEIE 1085

Query: 901  SL----ESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQNV 956
             +    +    + +E   Q+  +   +   +++   +   L  + + +E++ ++++    
Sbjct: 1086 KIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIKSIQSDKD 1145

Query: 957  ILQKDKVELLEENRQLRIEVVNGVEKENRSKSTLAALQAEMIELRQTNQVFQEENGKMLD 1016
            +L+K+K +L E+ R    +V   +EK+   ++TLA +Q E  +L + N+    E  ++  
Sbjct: 1146 MLEKEKHDL-EKTRSELYKVKEDLEKQK--ENTLAQIQKEREDLEKMNENITREMHEIKH 1202

Query: 1017 EKNSLCRNVSDLKDAKSSAEDENSVMFHDVLALSNLNLVYEIFFTENMVEKRALCEHLGN 1076
            ++  + +   +L   K+  ++    +  +   +       +   +E   ++  + + +  
Sbjct: 1203 QEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMET 1262

Query: 1077 LSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIERMDKELLEMDKRLKAAETSNAEFSRH 1136
            + +    L+++   + +  +  E E   +++S + +D++L  M  + +  E    +  + 
Sbjct: 1263 MKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQM 1322

Query: 1137 IEELKMEQEESTKIKENLD--RQILEQ-SENCMNHKKEIEHLNE--------------AN 1179
              EL+ E ++  KIKE     RQILE+ +E     +K++ HL E              AN
Sbjct: 1323 KIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAEDTKREKNSLDEMKVAN 1382

Query: 1180 ETLQFEMKTLLHEVEQHRVREEALNLELLNKENEFKLWENEAAAFYHDLQMSSICLALLE 1239
            E+   +++     +E+ +        ++  ++++ +L E+E      ++        + +
Sbjct: 1383 ESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQQSETEIEK 1442

Query: 1240 SKVS-ELTGVCKILDDESSAKSLENEHMREIISLLESEIGGLKEQLSAYVPLVSSLKEDF 1298
            S +  E   + K ++D  + +  + E     + ++  E+   K  L     L S ++   
Sbjct: 1443 SNIERERAAIIKDVEDLQNVQKYKEE-----LQIVTEELLTKKRNLEQ---LNSDVQHLM 1494

Query: 1299 NSLEHISLLWTKRNSVVGNGAQKDVVIETCLRKHSHQSARENEIVLIPDGVSDLLTLQTR 1358
             +LE + + + K+ + + +   +    E  L K   +      I+       ++  ++  
Sbjct: 1495 QTLEEVDIQYIKKKAELEHITSEIQKREQILEKQKKKLEENGWII------EEIEMMKVT 1548

Query: 1359 IRAVEKIMMEELKRRVKQK-SLTTESTPYSSLEIATYPKVENRKKEIELVEENVFDRNSW 1417
            + ++   ++++ +   K+K +L  E             +++    E++   EN+  R   
Sbjct: 1549 LESINMEILQKREDMEKEKENLRREKQETELFREMHREEIKKVDSELQKSRENIESREEK 1608

Query: 1418 RKKPKIRLLMKDIPLDRNVDDQNSKYLKREHRRTNDHVLELCENNEHEPLSAPTVDHAMI 1477
                   LL   + + R  ++     +++E +R  D  ++L EN + E            
Sbjct: 1609 INNKMEELLQMKVEMGRTKEE-----IEKESQRLQDATIDL-ENAKAE------------ 1650

Query: 1478 CHRSDDSGRYLNYSSELDI---EKELGVDKLELSKSVKEKTEDDKRRI----LERLSSDG 1530
              R +D      +   +DI   EKE  + K++L K  K  +E+ + ++    +E      
Sbjct: 1651 IQRQEDK-----FEDIIDIKIQEKEREI-KIQLDKETKRLSEEIELKVKDLEMEMADMKR 1704

Query: 1531 QKLAI-----LKMALQDLKKKTETKKKSKQGNDIEYETVKRHIEEVEEAVMQQVSINDQM 1585
            QK  I     +K   QDL K+ +  ++ K+  + E+  +++ I+E +  V +Q   +   
Sbjct: 1705 QKQEIEDTKDIKEQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQVSKQKEEDLTK 1764

Query: 1586 AKNVEEGASSLDREIPRRGSEQIGKLQFEVQNIQYILLKLAEENNNKVKNRISRK 1640
             K ++E   SL+ E   R  E   K + E+++I+    K  EE   +VK  +  K
Sbjct: 1765 QKEMKEERKSLE-ETKARIIEM--KTKAELEDIKKEKEKEEEEEEMRVKVEMDGK 1816



 Score =  201 bits (512), Expect = 1e-49
 Identities = 339/1668 (20%), Positives = 678/1668 (40%), Gaps = 296/1668 (17%)

Query: 126  ESHTSARPTHRSKKNERSSEESNGEVQTLREALAK----MQSDKDALFLQYQESLENLSK 181
            E H       + K+ +   ++   E+Q L++ L K    +  D+  L L+  E    L K
Sbjct: 349  EIHDIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSE----LDK 404

Query: 182  METDLNKA----QNNARGLDDRASEAEIQV-EILKESLMQLKADKDAGEVLYNQCLETIA 236
             +T++N      +N  + LD    E E Q  E+ KE     ++ K+  E +  +      
Sbjct: 405  QQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKNEIEKIKLETQHDRQ 464

Query: 237  RLESMLSQ--KDNIEAKNLKQELTRVVVQKDTVLLQYKQCLEKIPMLENKIALAEENSRM 294
            R+E M +Q  KD  E  NL +E  R    KD VL       EK   +E KI   + +  M
Sbjct: 465  RVEEMAAQIQKDRDEINNLIEETNR----KDMVLN------EKNRDIEEKIKSIQSDKDM 514

Query: 295  LNDQIERTELEVETLRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNK 354
            L       E E   L K  +E+ + ++ L     + L +I K   ++  + EN  +  ++
Sbjct: 515  L-------EKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHE 567

Query: 355  IEKEAEKLEISEKHRGMLEKSNQNLQLEAENLVQRIASKDHELLEKHTEIERLQT----L 410
            I+ + E++   +     L+   QNLQ E E   + I     +L  + +E+++ QT    +
Sbjct: 568  IKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDI 627

Query: 411  MHGEHSNFIQIESALQALQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGI 470
            M    +   Q++   + +++   + +KE+ N+    K      K ++L KQ F+EE   +
Sbjct: 628  METMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKL 687

Query: 471  ----VEENKTLHELNFSSTRSLKKQQMEI-SKLKEI---KEKLEREFHTSTEESNVLQR- 521
                +E  +   E++     +  K+Q +I  K+K I   K+ LE+E H   +  + L + 
Sbjct: 688  EQMKIELEREADEISKIKEETQNKRQRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKV 747

Query: 522  -------------ETHQIKDDIQHLNERYQAML-------EQLQSLGLNPNSFAASVRDL 561
                         E  + ++D++ +NE     +       EQ+       +     +++L
Sbjct: 748  KEDLEKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNL 807

Query: 562  QNENFMLKETCKKEHSE----------------------KEALREKSKDMNEVLMENACM 599
            Q E    KE   K+ S+                      K   ++  KD  E+  +   M
Sbjct: 808  QQELEKEKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEM 867

Query: 600  EFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESMQKILENN 659
            E      +     L   +K ++   QV +EEK+ L   K  L  +   I +  ++     
Sbjct: 868  EKEKHDFDQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNER 927

Query: 660  TVLEKSLSDAKIEFEGL------RIKSGDLEDCCKLLND--------EKNNLQNERSMLI 705
              LEK   + K E E          K  ++ D  K+ N+        EK+NL+  R  + 
Sbjct: 928  QSLEKMTEELKKEKESFTHLAEDTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENIS 987

Query: 706  SQLEIVEEKLSNLE--------------KKVTNLEEKYADVEKDKESAVNQVEELFASIL 751
             Q E VE K  NL               K+   +E++  ++E ++ + +  VE+L   I+
Sbjct: 988  KQTEDVENKKENLRLREDELWQLQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKII 1047

Query: 752  VQKENHSNHKHSSEARLANLENIVRVL-----QEEQRLGKVEFEQELDR------VVNAQ 800
                +  + K   EA   N   +++ +     +E   + K++ E + DR          Q
Sbjct: 1048 SLDRDSESLKLDREA-FENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQ 1106

Query: 801  IEMFILQNCIEELELKNFVL---LTECEKLVEASKFSDKVISELESENLMQLIEE----- 852
             +   + N IEE   K+ VL     + EK +++ + SDK + E E  +L +   E     
Sbjct: 1107 KDRDKINNLIEETNRKDMVLNEKNRDIEKKIKSIQ-SDKDMLEKEKHDLEKTRSELYKVK 1165

Query: 853  -------EFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESS 905
                   E  L +I+K + D+ K+   +  +      +EIK +E  +++  D+++ L++ 
Sbjct: 1166 EDLEKQKENTLAQIQKEREDLEKMNENITREM-----HEIKHQEEQMNQKQDELDQLKTE 1220

Query: 906  LVKSQEENQQLLVENSVLL---GSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDK 962
            +   Q   Q+L  E  +++     L + QSE +K +     + +  +N R+Q   L KDK
Sbjct: 1221 I---QNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQ---LDKDK 1274

Query: 963  VELLEENRQLRIEVVNGVEKENRSKSTLAALQAEMIELRQTNQVFQEENGKMLDEKNSLC 1022
             E+ E+ +++        E++N  +S   +L  ++  ++   QV +EE  K+   K  L 
Sbjct: 1275 EEMEEQKQEME------KERDNMDQSR-KSLDEDLKMMKLQKQVIEEEKNKLEQMKIELE 1327

Query: 1023 RNVSDLKDAKSSAEDENSVMFHDVLALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNN 1082
            R   D++  K   +++  ++                   E M E+  L +   +++HL  
Sbjct: 1328 READDIRKIKEETQNKRQIL-------------------EKMAEE--LKKERKDVAHLAE 1366

Query: 1083 DLNQEFGVLRKNFEVKEA-------ENVYLNESIERMDKELLEMDKRLKAAETSNAEFSR 1135
            D  +E   L +     E+       E   L E  E + K+  +++K          E  +
Sbjct: 1367 DTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLREDELEQ 1426

Query: 1136 HIEELKMEQEESTKIKENLDRQ------ILEQSENCMNHKKEIE-----------HLNEA 1178
               E+  +Q E+   K N++R+       +E  +N   +K+E++           +L + 
Sbjct: 1427 LQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQNVQKYKEELQIVTEELLTKKRNLEQL 1486

Query: 1179 NETLQFEMKTL--------LHEVEQHRVREEALNLELLNKENEFKLWENEAAAFYHDLQM 1230
            N  +Q  M+TL          + E   +  E    E + ++ + KL EN       +++M
Sbjct: 1487 NSDVQHLMQTLEEVDIQYIKKKAELEHITSEIQKREQILEKQKKKLEEN--GWIIEEIEM 1544

Query: 1231 SSICLALLESKV----SELTGVCKILDDESSAKSLENEHMREIISLLESEIGGLKEQLSA 1286
              + L  +  ++     ++    + L  E     L  E  RE I  ++SE+   +E + +
Sbjct: 1545 MKVTLESINMEILQKREDMEKEKENLRREKQETELFREMHREEIKKVDSELQKSRENIES 1604

Query: 1287 YVPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVIETCLRKHSHQSARENEIVLIP 1346
                +++  E+   ++            V  G  K+ +              E E   + 
Sbjct: 1605 REEKINNKMEELLQMK------------VEMGRTKEEI--------------EKESQRLQ 1638

Query: 1347 DGVSDLLTLQTRIRAVEKIMMEELKRRVKQKSLTTESTPYSSLEIATYPKVENRKKEIEL 1406
            D   DL   +  I+  E    + +  ++++K           ++I    + +   +EIEL
Sbjct: 1639 DATIDLENAKAEIQRQEDKFEDIIDIKIQEKE--------REIKIQLDKETKRLSEEIEL 1690

Query: 1407 VEENVFDRNSWRKKPKIRLLMKDIPLDRNVDDQNSKYLKREHRRTNDHVLELCENNEHEP 1466
              +++    +  K+ K     ++I   +++ +QN   +K+      D + +  E+  HE 
Sbjct: 1691 KVKDLEMEMADMKRQK-----QEIEDTKDIKEQNQDLMKQ-----RDLLEQEKEDINHE- 1739

Query: 1467 LSAPTVDHAMICHRSDDSGRYLNYSSELDIEKELGVDKLELSKSVKEKTEDDKRRILERL 1526
                      +  R D+      + +++  +KE  + K +  K  ++  E+ K RI+E  
Sbjct: 1740 -------WTQLQQRIDE------FDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMK 1786

Query: 1527 SSDGQKLAILKMALQDLKKKTETKKKSKQGNDIEYETVKRHIEEVEEAVMQQVSINDQMA 1586
            +         K  L+D+KK+ E K++ ++   ++ E   + ++ ++  + ++ S  D   
Sbjct: 1787 T---------KAELEDIKKEKE-KEEEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQ 1836

Query: 1587 KNVEEGASSLDREIPRRGSEQIGKLQFEVQNIQYILLKLAEENNNKVK 1634
            K + +     D++I  +  + + K++ E+   +  + +   E  NK+K
Sbjct: 1837 KKLND-----DKKIIEQEKQNLEKMKSEIMKQRQQMEEERSELENKIK 1879



 Score =  169 bits (428), Expect = 7e-40
 Identities = 295/1568 (18%), Positives = 658/1568 (41%), Gaps = 228/1568 (14%)

Query: 221  KDAGEVLYNQCLETIARLESMLSQKDNIEA--KNLKQELTRVVVQKDTVLLQYKQCLEKI 278
            K   +VL    +   + L  +L ++ N++   +N+ ++   V  +K+ + L+     EK+
Sbjct: 1    KRKNQVLDEMKVANESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLRE----EKL 56

Query: 279  PMLENKIALAEENSRMLNDQIERTEL----EVETLRKNLAEMNEERDSLSV---LYHHCL 331
              L+ +I   +  +      IER       +VE L+  +  ++ + +SL +    + +  
Sbjct: 57   KQLQAEIHKQQSETEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEK 116

Query: 332  EKISKMENEILHVQENAEQLKNKIEKEAEK--------LEISEKHRGMLEKSNQNLQLEA 383
            E++ +M+ E+    +  E++K + + E ++        +E     R  L K+ + +Q + 
Sbjct: 117  EELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLNKNKEEMQEQK 176

Query: 384  ENLVQRIASKDH--ELLEKHTEIERLQTLMHGEHSNF-----IQIESALQALQKLYSQSQ 436
            + + +     D   + L+K+ ++ +LQ  +  E  N      I++E     ++K+  ++Q
Sbjct: 177  QEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMKIELEKEADEIRKIKEETQ 236

Query: 437  KEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEIS 496
             E++ L         + ++L+  K+ F    +    E K L ++  ++   +   Q E S
Sbjct: 237  NERQRLEK-------MTEELKKEKESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKS 289

Query: 497  KLKEIKEKLEREFHTSTEESNVL---QRETHQIKDDIQHLNERYQAMLEQLQSLGLNPNS 553
             L+E++E + ++   S +E   +   + E  Q++ +I H  +  Q   E L+ +      
Sbjct: 290  NLEEMRENISKQTEDSEKEKEKIRLREDELEQLQAEI-HKQQEIQKEREDLEKMN---EK 345

Query: 554  FAASVRDLQNENFMLKETCKKEHSEKEALREKSKDMNEVLMENACMEFSLLGLNDELDGL 613
            F   + D++++   +K+                                     DELD L
Sbjct: 346  FTIEIHDIKHQEEQMKQK-----------------------------------QDELDQL 370

Query: 614  RGTVKEIQQFCQVLQEEKSILADEKSTL-LSQLQI------ITESMQKILENNTVLEKSL 666
            +    EIQ   Q L++EK I+  ++S L L Q ++      + + M+ +      L+K  
Sbjct: 371  K---TEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDK 427

Query: 667  SDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVEEKLSNLEK---KVT 723
             + + + + +  +  D +         KN ++  +       + VEE  + ++K   ++ 
Sbjct: 428  EETEEQKQEMEKEKHDFD------QSRKNEIEKIKLETQHDRQRVEEMAAQIQKDRDEIN 481

Query: 724  NLEEKYADVEKDKESAVNQVEELFASILVQKENHSNHKHSSEARLANLENIVRVL--QEE 781
            NL E+    +         +EE   SI   K+     KH  E   + L  +   L  Q+E
Sbjct: 482  NLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKE 541

Query: 782  QRLGKVEFEQELDRVVNAQI--EMFILQNCIEELELKNFVLLTECEKLVEASKFSDKVIS 839
              L +++ E+E    +N  I  EM  +++  E++  K      E ++L            
Sbjct: 542  NTLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQ----DELDQL------------ 585

Query: 840  ELESENLMQLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEI----KKEEIPISRI 895
            + E +NL Q +E+E  +    + ++D+ +     ++D      N+I    K E   + + 
Sbjct: 586  KTEIQNLQQELEKEKEIIMKDRSQLDLRQ----SELDKQQTNMNDIMETMKNERKQLDKD 641

Query: 896  LDKIESLESSLVK---SQEENQQLLVENSVLLGSLQQHQSEGEKLKLEKKTVE------- 945
             +++E  +  + K   + +++++ L E+   +  LQ+   E EK KLE+  +E       
Sbjct: 642  KEEMEEQKQEMEKERDNMDQSRKSLDEDQKKM-KLQKQMFEEEKNKLEQMKIELEREADE 700

Query: 946  -----QEFENMREQNV-----ILQKDKVELLEENR----QLRIEVVNGVEK-ENRSKSTL 990
                 +E +N R++++      +Q DK ++LE+ R    + R E+    E  E + ++TL
Sbjct: 701  ISKIKEETQNKRQRDIEEKIKSIQSDK-DMLEKERHNLEKTRSELYKVKEDLEKQKENTL 759

Query: 991  AALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVLALS 1050
            A +Q E  ++ + N+    E  ++  ++  + +   +L   K+  ++    +  +   + 
Sbjct: 760  AEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIM 819

Query: 1051 NLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIE 1110
                 +++  +E   ++  + + +  + +    L+++   + +  +  E E    ++S +
Sbjct: 820  KDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRK 879

Query: 1111 RMDKELLEMDKRLKAAETSNAEFSRHIEELKMEQEESTKIKENL--DRQILEQ-SENCMN 1167
             +DK+L  M  + +  E    +  +   EL+ E +E  KIKE    +RQ LE+ +E    
Sbjct: 880  SLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKK 939

Query: 1168 HKKEIEHLNE--------------ANETLQFEMKTLLHEVEQHRVREEALNLELLNKE-- 1211
             K+   HL E              ANE+L  +++     +E+ R        ++ NK+  
Sbjct: 940  EKESFTHLAEDTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKEN 999

Query: 1212 ---NEFKLWENEAAAF--YHDLQMSSICL----ALLESKVSELTGVCKILDDESSAKSLE 1262
                E +LW+ +A  +    +++   I +    A +   V +L      LD +S +  L+
Sbjct: 1000 LRLREDELWQLQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLD 1059

Query: 1263 N---EHMREIISLLESEIGGLKEQL-----------SAYVPLVSSLKEDFNSLEHISLLW 1308
                E+ RE++  +++E+    +++                + + +++D + + ++ +  
Sbjct: 1060 REAFENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNL-IEE 1118

Query: 1309 TKRNSVVGNGAQKDV--------VIETCLRKHSHQSAR-ENEIVLIPDGV-----SDLLT 1354
            T R  +V N   +D+          +  L K  H   +  +E+  + + +     + L  
Sbjct: 1119 TNRKDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQ 1178

Query: 1355 LQTRIRAVEKI------MMEELKRRVKQKSLTTESTPYSSLEIATYPKVENRKKEIELVE 1408
            +Q     +EK+       M E+K + +Q +   +       EI    +   ++KEI +  
Sbjct: 1179 IQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKA 1238

Query: 1409 ENVFDRNSWRKKPKIRLLMKDIPLDRNVDDQNSKYLKREHRRTNDHVLELCENNEHEPLS 1468
             +  DR    +  K +  M DI ++   +++      +E        +E   +N  +   
Sbjct: 1239 RSQLDRRQ-SELDKQQTNMNDI-METMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRK 1296

Query: 1469 APTVDHAMICHRSDDSGRYLNYSSELDIEKELGVDKLELSKSVKEKTEDDKRRILERLSS 1528
            +   D  M+  +        N   ++ IE E   D +   + +KE+T+ +KR+ILE+++ 
Sbjct: 1297 SLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDI---RKIKEETQ-NKRQILEKMAE 1352

Query: 1529 DGQK----LAILKMALQDLKKKTETKKKSKQGNDIEYETVKRHIEEVEEAVMQQVSINDQ 1584
            + +K    +A L    +  K   +  K + + +  + +  K ++EE++E + +Q    ++
Sbjct: 1353 ELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEK 1412

Query: 1585 MAKNV---EEGASSLDREIPRRGSE-QIGKLQFEVQNIQYILLKLAEENNNKVKNRISRK 1640
                +   E+    L  EI ++ SE +I K   E +    I      +N  K K  +   
Sbjct: 1413 EKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQNVQKYKEELQIV 1472

Query: 1641 TGILLRRK 1648
            T  LL +K
Sbjct: 1473 TEELLTKK 1480


>UniRef100_UPI0000437334 UPI0000437334 UniRef100 entry
          Length = 3065

 Score =  211 bits (538), Expect = 1e-52
 Identities = 366/1796 (20%), Positives = 746/1796 (41%), Gaps = 284/1796 (15%)

Query: 39   KVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAE-------------- 84
            K++ M   +E EAD  ++  E    KR  L K+ EE  R   +LA               
Sbjct: 760  KLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDE 819

Query: 85   ---RYDHAMGELRHAHKTMPEAFPNSAY---YILNDDSPCGSLGPDAESHTSARPTHRSK 138
                 + +M +L+     + E   N +    YI N+           E       T   K
Sbjct: 820  MKVANESSMADLQREKSILEEMRENISKLKEYIDNEKEKSKL----REDELKKLQTEVQK 875

Query: 139  KNERSSEESNGEVQTLREALAKMQSD----KDALFLQYQESLE---NLSKMETDLNKAQ- 190
            +     E+SN  ++ +RE ++K   D    K+ L L+  E  +    + K + ++ K + 
Sbjct: 876  QQNLQKEKSN--LEEMRENISKQTEDVENKKENLRLREDELWQLQAEIYKQQREIEKEKI 933

Query: 191  ----------NNARGLD------DRASEA--------EIQVEILKESLMQLKADKDAGEV 226
                       N   L       DR SE+        E + E+LK+   +L+ + D  E 
Sbjct: 934  NIESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELEREADEIEK 993

Query: 227  LYNQCLETIARLESMLSQ--KDNIEAKNLKQELTRVVVQKDTVLLQYKQCLEK-IPMLEN 283
            +  +      R+E M +Q  KD  +  NL +E  R    KD VL +  + +EK I  +++
Sbjct: 994  IKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNR----KDMVLNEKNRDIEKKIKSIQS 1049

Query: 284  KIALAEENSRMLN---DQIERTELEVETLRKN-LAEMNEERDSLSVLYHHC---LEKISK 336
               + E+    L     ++ + + ++E  ++N LA++ +ER+ L  +  +    + +I  
Sbjct: 1050 DKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHEIKH 1109

Query: 337  MENEILHVQENAEQLKNKIEKEAEKLE----ISEKHRGMLEKSNQNLQLEAENL---VQR 389
             E ++   Q+  +QLK +I+   ++LE    I  K R  L++    L  +  N+   ++ 
Sbjct: 1110 QEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMET 1169

Query: 390  IASKDHELLEKHTEIERLQTLMHGEHSNFIQIESALQA---LQKLYSQSQKEQRNLALEL 446
            + ++  +L +   E+E  +  M  E  N  Q   +L     + KL  Q  +E++N   ++
Sbjct: 1170 MKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQM 1229

Query: 447  KYGLLLLKD---------------LELSKQDFKEEMQGIVE-------ENKTLHELNFSS 484
            K  L    D               LE   ++ K+E + +         E  +L E+  ++
Sbjct: 1230 KIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAEDTKREKNSLDEMKVAN 1289

Query: 485  TRSLKKQQMEISKLKEIKEKLERE----------FHTSTEESNVLQRETH-QIKDDIQHL 533
              S+   Q E S L+E+KE + ++               +E   LQ E H Q K +IQ  
Sbjct: 1290 ESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQQKREIQQE 1349

Query: 534  NERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKET---CKKEHSEKEALREKSKDMN 590
             ++ Q+   Q+  L    +       DL  +   LK+T    K++  + E  R++  +M+
Sbjct: 1350 KKKLQSK-NQMVELKRQIDKLIELKADLLQQQTELKKTKADLKQQMDDLEKTRKQLAEMS 1408

Query: 591  EVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITE 650
            E +      E+  L     ++ L+   ++++     +++EK  L + KS L  QL+ +  
Sbjct: 1409 ETVTTEQ-NEYRKL-----IEELQREKEQLEISKNQIEQEKKDLQNMKSNLERQLESLRH 1462

Query: 651  SMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEI 710
                + +    LEK  S++K     +R +  DLE+C   +  EK  ++ E   L    E 
Sbjct: 1463 EKANVEDEKNALEKMRSESKEIQNAIRKEREDLENCWVEIEGEKKRMEEETRRLEMHREE 1522

Query: 711  VEEKLSNLEKKVTNLEEKYADVEKDKESAVN-QVEELFASILVQKENH---------SNH 760
            +++  S L+K   N+E +   +    E  +  +VE       ++KE+           N 
Sbjct: 1523 IKKVDSELQKSRENIESREEKINNKMEELLQMKVEMGRTKEEIEKESQRLQDATIDLENA 1582

Query: 761  KHSSEARLANLENIVRV-LQEEQRLGKVEFEQELDR--------VVNAQIEMFILQNCIE 811
            K   + +    E+I+ + +QE++R  K++ ++E  R        V + ++EM  ++   +
Sbjct: 1583 KAEIQRQEDKFEDIIDIKIQEKEREIKIQLDKETKRLSEEIELKVKDLEMEMADMKRQKQ 1642

Query: 812  ELELKNFVLLTECEKLVEASKFSDKVISELE---------SENLMQ---LIEEE------ 853
            E+E     L  E E++   ++ + +   +LE         +++LM+   L+E+E      
Sbjct: 1643 EIEDTKAHLEKEKEEMKSITEETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKEDINH 1702

Query: 854  ---FLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKE----EIPISRILD-----KIES 901
                L  RI +F   + K     Q + D     E+K+E    E   +RI++     ++E 
Sbjct: 1703 EWTQLQQRIDEFDAQVSK-----QKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELED 1757

Query: 902  LESSLVKSQEENQ-QLLVE---------NSVLLGSLQQHQSEGEKLKLEKKTVEQEFENM 951
            ++    K +EE + ++ VE          S L     +   E +KL  +KK +EQE +N+
Sbjct: 1758 IKKEKEKEEEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQKKLNDDKKIIEQEKQNL 1817

Query: 952  REQNVILQKDKVELLEENRQLRIEV----VNGVEKENRSKSTLAALQAEMIELRQTNQVF 1007
             +    + K + ++ EE  +L  ++    +   + EN SK  +  L  E+ E +   Q  
Sbjct: 1818 EKMKSEIMKQRQQMEEERSELENKIKQTYIEKCDIEN-SKEIVQKLMVEVEEQKHEIQFQ 1876

Query: 1008 QE----ENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVLALSNLNLVYEIFFTEN 1063
            +E    E  K+ DE++ L +N S+L++      + N ++  +   L  +    E    + 
Sbjct: 1877 KEELDIERQKIADEQDLLIQNKSELQNENERIRNLNEIIKKERETLKEM----EAHLEKK 1932

Query: 1064 MVEKRALCEHL----GNLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIERMDKELLEM 1119
              E +++ E       +L  ++ D+N++   L    ++ E E   +N   +++ + + E 
Sbjct: 1933 KEEIKSVSEETRRLKEDLEKMSTDVNKQNKDLMNQRDLLEQEREEINHKWKQLQQRIDEF 1992

Query: 1120 DKRLKA-AETSNAEFSRHIEELKMEQEESTKIKENLDR---QILEQSENCMNHKKEIEHL 1175
            D ++K+  E   +E     ++L  +++   + KE+L++   +I++Q +     + E++  
Sbjct: 1993 DAQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELD-- 2050

Query: 1176 NEANETLQFEMKTLLHEVEQHRVREEALNLELLNKENEFKLWENEAAAFYHDLQMSSICL 1235
               N+  Q +++   H++E  +   + L +E+  +  + +L + E      D++   I  
Sbjct: 2051 ---NKIKQTDLER--HDIENSKEIVQKLMVEVEEQRKDIRLQKEEL-----DIERQKIA- 2099

Query: 1236 ALLESKVSELTGVCKILDDESSAKSLENEHMREIISLLESEIGGLKEQLSAYVPLVSSLK 1295
               + +   +    K+ ++    K ++ E  +E  +L E E    KE+      +  + +
Sbjct: 2100 ---DEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQR 2156

Query: 1296 EDFNSLEHISLLWTKRNSVVGNGAQKDVVIETCLRKHSHQSARENEIVLIPDGVSDLLTL 1355
                 LE +S    K+N  + N  Q+D++ +     +   +  +  I      VS     
Sbjct: 2157 RQKEDLEKMSTDVNKQNQDLMN--QRDLLKQEREEINHKWTQLQQRIDEFDAQVS----- 2209

Query: 1356 QTRIRAVEKIMMEELKRRVKQKSLTTESTPYSSLEIATYPKVENRKKEIELVEENVFDRN 1415
                +  E+ + ++ K   ++KSL  E T    +E+ T  + E  KKE E  EE V    
Sbjct: 2210 ----KQKEEDLTKQKKMEEERKSL--EETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAK 2263

Query: 1416 SWRKKPKIRLLMKDIPLDRNVDDQNSKYL----------KREHRRTNDHVLELCENNEHE 1465
               KK ++  +   +   R+  D   K L          K +  +    +++  +  E E
Sbjct: 2264 VEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEE 2323

Query: 1466 PL-----------------SAPTVDHAMICHRSDDSGRYLNYSSELDIEKELGVDKLELS 1508
                               ++  +   ++    +          ELDIE++   D+ +L 
Sbjct: 2324 RSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLL 2383

Query: 1509 KSVKEKTEDDKRRIL---ERLSSDGQKL----AILKMALQDLKKKTETKKKSKQGNDIEY 1561
               K + +++  RI    E +  + + L    A L+   +++K  TE  ++ K+    + 
Sbjct: 2384 IQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSITEETRRQKE----DL 2439

Query: 1562 ETVKRHIEEVEEAVMQQVSINDQMA-------KNVEEGASSLDREIPRRGSEQIGK 1610
            E +  HI E ++ +  Q  + +Q         K +++     D ++ ++  E + K
Sbjct: 2440 EKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEEDLPK 2495



 Score =  206 bits (523), Expect = 6e-51
 Identities = 357/1679 (21%), Positives = 702/1679 (41%), Gaps = 263/1679 (15%)

Query: 39   KVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHAMGELRHAHK 98
            K++ M   +E+EAD   +  E    +R  L K+ EE  +      E + H   + +   K
Sbjct: 363  KLEQMKIELEKEADEIRKIKEETQNERQRLEKMTEELKKE----KESFTHLAEDTKTEKK 418

Query: 99   TMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSK--KNERSSEESNGEVQTLRE 156
             + +        + N+     SL  D +   S     R    K    SE+   +++   +
Sbjct: 419  ILDKM------KVANE-----SLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLRED 467

Query: 157  ALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDDRASEAEIQVEILKESLMQ 216
             L ++Q++     +  Q+    + K   +   A++    LD  A E E   E+LK+   +
Sbjct: 468  ELEQLQAE-----IHKQQGEIKMEKSNNENRDAESLK--LDREAFENE--KEVLKQMKTE 518

Query: 217  LKADKDAGEVLYNQCLETIARLESMLSQ--KDNIEAKNLKQELTRVVVQKDTVLLQYKQC 274
            L+ + D  E +  +      R+E M +Q  KD  E  NL +E  R    KD VL      
Sbjct: 519  LEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDEINNLIEETNR----KDMVLN----- 569

Query: 275  LEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEERDSLSVLYHHCLEKI 334
             EK   +E KI   + +  ML       E E   L K  +E+ + ++ L     + L +I
Sbjct: 570  -EKNRDIEEKIKSIQSDKDML-------EKEKHDLEKTRSELYKVKEDLEKQKENTLAEI 621

Query: 335  SKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQLEAENLVQRIASKD 394
             K   ++  + EN  +  ++I+ + E++   +     L+   QNLQ E E   + I    
Sbjct: 622  QKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDR 681

Query: 395  HELLEKHTEIERLQT----LMHGEHSNFIQIESALQALQKLYSQSQKEQRNLALELKYGL 450
             +L  + +E+++ QT    +M    +   Q++   + +++   + +KE+ N+    K   
Sbjct: 682  SQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLD 741

Query: 451  LLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEISKLKEIKEKLEREFH 510
               K ++L KQ F+E      E+NK L ++       L+++  EISK+KE  +   +   
Sbjct: 742  EDQKKMKLQKQMFEE------EKNK-LEQMKI----ELEREADEISKIKEETQNKRQRLE 790

Query: 511  TSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKE 570
              TEE   L RE    K+ + HL E  +   + L  + +   S   S+ DLQ E  +L+E
Sbjct: 791  KMTEE---LIRE----KESLAHLAEDTKTEKKILDEMKVANES---SMADLQREKSILEE 840

Query: 571  TCKKEHSEKEAL---REKSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVL 627
              +     KE +   +EKSK     L E            DEL  L+  V++ Q     L
Sbjct: 841  MRENISKLKEYIDNEKEKSK-----LRE------------DELKKLQTEVQKQQN----L 879

Query: 628  QEEKSILADEKSTLLSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCC 687
            Q+EKS L + +  +  Q    TE ++   EN  + E  L   + E    +          
Sbjct: 880  QKEKSNLEEMRENISKQ----TEDVENKKENLRLREDELWQLQAEIYKQQ---------- 925

Query: 688  KLLNDEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELF 747
            + +  EK N+++ER+ +I  +E       +L+ K+ +L+     ++ D+E+  N+ E L 
Sbjct: 926  REIEKEKINIESERAAIIKNVE-------DLQHKIISLDRDSESLKLDREAFENEREVL- 977

Query: 748  ASILVQKENHSNHKHSSEARLANLENI-VRVLQEEQRLGKVEFEQELDRVVNAQIEMFIL 806
                         K   E     +E I +    + QR+ ++  + + DR          +
Sbjct: 978  ----------KQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQKDRDK--------I 1019

Query: 807  QNCIEELELKNFVL---LTECEKLVEASKFSDKVISELESENLMQLIEE----------- 852
             N IEE   K+ VL     + EK +++ + SDK + E E  +L +   E           
Sbjct: 1020 NNLIEETNRKDMVLNEKNRDIEKKIKSIQ-SDKDMLEKEKHDLEKTRSELYKVKEDLEKQ 1078

Query: 853  -EFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQE 911
             E  L +I+K + D+ K+   +  +      +EIK +E  +++  D+++ L++ +   Q 
Sbjct: 1079 KENTLAQIQKEREDLEKMNENITREM-----HEIKHQEEQMNQKQDELDQLKTEI---QN 1130

Query: 912  ENQQLLVENSVLL---GSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEE 968
              Q+L  E  +++     L + QSE +K +     + +  +N R+Q   L KDK E+ E+
Sbjct: 1131 LQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQ---LDKDKEEMEEQ 1187

Query: 969  NRQLRIEVVNGVEKENRSKSTLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDL 1028
             +++        E++N  +S   +L  ++  ++   QV +EE  K+   K  L R   D+
Sbjct: 1188 KQEME------KERDNMDQSR-KSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDI 1240

Query: 1029 KDAKSSAEDENSVM---------------------FHDVLALSNLNLVYEIFFTENMVEK 1067
            +  K   +++  ++                       +  +L  + +  E    +   EK
Sbjct: 1241 RKIKEETQNKRQILEKMAEELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKEK 1300

Query: 1068 RALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIERMDKELLEMDKRLKAAE 1127
              L E   N+S    D+ +E    +    ++E E   L   I +  K  ++ +K+   ++
Sbjct: 1301 SNLEEMKENISKQTEDIEKE----KDKIRLREDELEQLQAEIHKQQKREIQQEKKKLQSK 1356

Query: 1128 TSNAEFSRHIE-------ELKMEQEESTKIKENLDRQILEQSENCMNHKKEIEHLNEANE 1180
                E  R I+       +L  +Q E  K K +L +Q+    ++    +K++  ++E   
Sbjct: 1357 NQMVELKRQIDKLIELKADLLQQQTELKKTKADLKQQM----DDLEKTRKQLAEMSETVT 1412

Query: 1181 TLQFEMKTLLHEVEQHRVREEALNLELLNKENEFKLWENEAAAFYHDLQMSSICLALLES 1240
            T Q E + L+ E+++ +   E L +     E E K  +N  +     L+      A +E 
Sbjct: 1413 TEQNEYRKLIEELQREK---EQLEISKNQIEQEKKDLQNMKSNLERQLESLRHEKANVED 1469

Query: 1241 KVSELTGVCKILDDESSAKSLEN--EHMREIISLLESEIGGLKEQLSAYVPLVSSLKEDF 1298
            + + L  +       S +K ++N     RE +     EI G K+++      +   +E+ 
Sbjct: 1470 EKNALEKM------RSESKEIQNAIRKEREDLENCWVEIEGEKKRMEEETRRLEMHREEI 1523

Query: 1299 NSLEHISLLWTKRNSVVGNGAQKDVVIETCLRKHSHQSARENEI----VLIPDGVSDLLT 1354
              ++  S L   R ++     + +  +E  L+        + EI      + D   DL  
Sbjct: 1524 KKVD--SELQKSRENIESREEKINNKMEELLQMKVEMGRTKEEIEKESQRLQDATIDLEN 1581

Query: 1355 LQTRIRAVE-------KIMMEELKRRVKQKSLTTESTPYSSLEIATYPK-VENRKKEIEL 1406
             +  I+  E        I ++E +R +K +    + T   S EI    K +E    +++ 
Sbjct: 1582 AKAEIQRQEDKFEDIIDIKIQEKEREIKIQ--LDKETKRLSEEIELKVKDLEMEMADMKR 1639

Query: 1407 VEENVFDRNSWRKKPKIRLLMKDIPLDRNVDDQNSKYLKREHRRTNDHVLELCENNEHEP 1466
             ++ + D  +  +K K    MK I  +     ++ + +  + +  N  +++  +  E E 
Sbjct: 1640 QKQEIEDTKAHLEKEKEE--MKSITEETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQE- 1696

Query: 1467 LSAPTVDH--AMICHRSDDSGRYLNYSSELDIEKELGVDKLELSKSVKEKTEDDKRRILE 1524
                 ++H    +  R D+      + +++  +KE  + K +  K  ++  E+ K RI+E
Sbjct: 1697 --KEDINHEWTQLQQRIDE------FDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIE 1748

Query: 1525 RLSSDGQKLAILKMALQDLKKKTETKKKSKQGNDIEYETVKRHIEEVEEAVMQQVSINDQ 1584
              +         K  L+D+KK+ E K++ ++   ++ E   + ++ ++  + ++ S  D 
Sbjct: 1749 MKT---------KAELEDIKKEKE-KEEEEEEMRVKVEMDGKELDRIKSELKRERSEIDH 1798

Query: 1585 MAKNVEEGASSLDREIPRRGSEQIGKLQFEVQNIQYILLKLAEENNNKVKNRISRKTGI 1643
              K + +     D++I  +  + + K++ E+   +  + +   E  NK+K     K  I
Sbjct: 1799 EQKKLND-----DKKIIEQEKQNLEKMKSEIMKQRQQMEEERSELENKIKQTYIEKCDI 1852



 Score =  204 bits (518), Expect = 2e-50
 Identities = 344/1716 (20%), Positives = 734/1716 (42%), Gaps = 242/1716 (14%)

Query: 45   KLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHAMGELRHAHKTMPEAF 104
            KLIE +AD   ++ E+  K + +L + +++  +  + LAE  +    E     K + E  
Sbjct: 1368 KLIELKADLLQQQTELK-KTKADLKQQMDDLEKTRKQLAEMSETVTTEQNEYRKLIEE-- 1424

Query: 105  PNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKNERSSEESNGE--VQTLREALAKMQ 162
                            L  + E    ++     +K +  + +SN E  +++LR   A ++
Sbjct: 1425 ----------------LQREKEQLEISKNQIEQEKKDLQNMKSNLERQLESLRHEKANVE 1468

Query: 163  SDKDALFLQYQESLE---NLSKMETDLNKAQNNARGLDDRASEAEIQVEILKESLMQLKA 219
             +K+AL     ES E    + K   DL        G   R  E   ++E+ +E + ++ +
Sbjct: 1469 DEKNALEKMRSESKEIQNAIRKEREDLENCWVEIEGEKKRMEEETRRLEMHREEIKKVDS 1528

Query: 220  DK-------DAGEVLYNQCLETIARL-------------ESMLSQKDNIEAKNLKQELTR 259
            +        ++ E   N  +E + ++             ES   Q   I+ +N K E+ R
Sbjct: 1529 ELQKSRENIESREEKINNKMEELLQMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQR 1588

Query: 260  VVVQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEE 319
               + + ++    Q  E+    E KI L +E  R+     E  EL+V+ L   +A+M  +
Sbjct: 1589 QEDKFEDIIDIKIQEKER----EIKIQLDKETKRLS----EEIELKVKDLEMEMADMKRQ 1640

Query: 320  RDSLSVLYHHC---LEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSN 376
            +  +     H     E++  +  E    +E+ E++   I+++ + L    K R +LE+  
Sbjct: 1641 KQEIEDTKAHLEKEKEEMKSITEETRRQKEDLEKMSTDIKEQNQDLM---KQRDLLEQEK 1697

Query: 377  QNLQLEAENLVQRIASKDHEL-------LEKHTEIERLQTLMHGEHSNFIQIESALQALQ 429
            +++  E   L QRI   D ++       L K  E++  +  +    +  I++++  + L+
Sbjct: 1698 EDINHEWTQLQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAE-LE 1756

Query: 430  KLYSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSLK 489
             +  + +KE+    + +K  +   K+L+  K + K E   I  E K L++         +
Sbjct: 1757 DIKKEKEKEEEEEEMRVKVEMDG-KELDRIKSELKRERSEIDHEQKKLND--DKKIIEQE 1813

Query: 490  KQQMEISKLKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQAML----EQLQ 545
            KQ +E  K + +K++ + E   S  E+ +  ++T+  K DI++  E  Q ++    EQ  
Sbjct: 1814 KQNLEKMKSEIMKQRQQMEEERSELENKI--KQTYIEKCDIENSKEIVQKLMVEVEEQKH 1871

Query: 546  SLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDMNEVLM-ENACMEFSLL 604
             +           + + +E  +L +   +  +E E +R    ++NE++  E   ++    
Sbjct: 1872 EIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIR----NLNEIIKKERETLKEMEA 1927

Query: 605  GLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESMQKILENNTVLEK 664
             L  + + ++   +E ++  + L++  + +  +   L++Q  ++ +  ++I      L++
Sbjct: 1928 HLEKKKEEIKSVSEETRRLKEDLEKMSTDVNKQNKDLMNQRDLLEQEREEINHKWKQLQQ 1987

Query: 665  SLS--DAKIEFEGLRIKSG------DLEDCCKLLNDEKNNLQNERSMLISQLEIVEEKLS 716
             +   DA+I+ +  R++S        L D  K++  EK +L+  +S ++ Q + +EE+ S
Sbjct: 1988 RIDEFDAQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERS 2047

Query: 717  NLEKKVTNLEEKYADVEKDKE---SAVNQVEELFASILVQKE--NHSNHKHSSEARLANL 771
             L+ K+   + +  D+E  KE     + +VEE    I +QKE  +    K + E  L  +
Sbjct: 2048 ELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLV-V 2106

Query: 772  ENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQNCIEELELKNFVLLTECEKLVEAS 831
            +N  ++  E +R+ +++ E + ++    ++E  + +   E+ E+++ +  T+  +  +  
Sbjct: 2107 QNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRK---EKEEMRSVIEETQRRQKEDLE 2163

Query: 832  KFSDKVISE----LESENLMQLIEEEF------LLHRIRKFKMDIHKVCGVLQIDSDGGG 881
            K S  V  +    +   +L++   EE       L  RI +F   + K     Q + D   
Sbjct: 2164 KMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSK-----QKEEDLTK 2218

Query: 882  DNEIKKE-------EIPISRILDKIESLESSLVKSQEENQQLLVENSVLLGSLQQHQSEG 934
              ++++E       +I I  +  K E  +    K +EE + +  +  +    L Q +S+ 
Sbjct: 2219 QKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQL 2278

Query: 935  EKLKLE-----------KKTVEQEFENMREQNVILQKDKVELLEENRQLRIEV----VNG 979
            E+++ E           KK +EQE E++ +    + K + ++ EE  +L  ++    +  
Sbjct: 2279 ERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEK 2338

Query: 980  VEKENRSKSTLAALQAEMIELRQTNQVFQEE----NGKMLDEKNSLCRNVSDLKDAKSSA 1035
             + EN SK  +  L  E+ E +   Q  +EE      K+ DE++ L +N S+L++     
Sbjct: 2339 CDIEN-SKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERI 2397

Query: 1036 EDENSVMFHDVLALSNLNLVYEIFFTENMVEKRALCEHLG----NLSHLNNDLNQEFGVL 1091
            ++ N V+  +   L  +    E +  +   E +++ E       +L  ++  +N++   L
Sbjct: 2398 KNINEVIKKERETLKEM----EAYLEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDL 2453

Query: 1092 RKNFEVKEAENVYLNESIERMDKELLEMDKRLKAAETSNAEFSRHIEE---LKMEQEEST 1148
            R   ++ E E   +N   +++ + + E D          A+ S+  EE    + E +E  
Sbjct: 2454 RSQRDLLEQEREEINHKWKQLQQRIDEFD----------AQVSKQKEEDLPKEKEMKEDR 2503

Query: 1149 KIKENLDRQILEQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLELL 1208
            K  E     ILE     M  K E E + +  E           E E+  +R   + +E+ 
Sbjct: 2504 KSLEETKANILE-----MKTKAEPEEIKKEKEK----------EEEEQEMR---VKVEME 2545

Query: 1209 NKENEFKLWENEAAAFYHDLQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMRE 1268
             KE E               Q+ S     LE   SE+    K L+D+      E E + +
Sbjct: 2546 RKEIE---------------QIKS----QLERVRSEMDHEQKKLNDDKKMIEQEKEDLEK 2586

Query: 1269 IISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVIETC 1328
            + S +  +   ++E+ S     +     + + +E+   +  K            +++E  
Sbjct: 2587 MKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVEK------------LMVEVE 2634

Query: 1329 LRKHSHQSARENEIVLIPDGVSDLLTLQTRIRAVEKIMMEELKRRVKQ--KSLTTESTPY 1386
             +KH  Q  +E E+ +    ++D   L  +     KI  +    R+K+  + +  E    
Sbjct: 2635 KQKHEIQFQKE-ELDIERQKIADEQDLLIQ----NKIEQQNENERIKEMDEEIKKERETL 2689

Query: 1387 SSLEIATYPKVENRKKEIELVEENVFDRNSWRKKPKIRLLMKDIPLDRNVDDQNSKYLKR 1446
              +E+     ++  K+EIE V E      + R+K  +  +  DI  ++  D  N + L +
Sbjct: 2690 KEMEV----NLQKEKEEIESVIEE-----TQRRKEDLEKMSTDIN-EQKQDLMNQRDLLK 2739

Query: 1447 EHRRTNDHVLELCE---------NNEHEPLSAPTVDHAMICHRSD---DSGRYLNYSSEL 1494
            + R   +H L   +         N + E      + + +   +S+   +  +      E+
Sbjct: 2740 QEREEMNHKLTQLQQRIDEFETTNLQKEKNKTEELKNILEREKSELYQEKAQVQQQKHEM 2799

Query: 1495 DIEKELGVDKLELSKSVKEKTEDDKRRILERLSSDGQKLAILKMALQDLKKKTETKKKSK 1554
            +  ++    ++E  + ++ + ED+K+ +L RLS +  ++  LK  +Q  K+  E +KK+ 
Sbjct: 2800 ETIRKTMKSEMENLECLRNELEDEKKSMLSRLSMEKHEIDKLKTEIQSEKESIEEEKKTL 2859

Query: 1555 QGNDIEYETVKRHIEE-VEEAVMQQVSINDQMAKNVEEGASSLDREIPRRGSEQIGKLQF 1613
            +    E E+ +  ++  +E+  M ++SI  +   ++EE  + L R+  +   E    +Q 
Sbjct: 2860 KQLKDENESKRTQLDNTIEKMNMDKLSIQRE-KDSLEEIKADLQRKAEKLDEEMRKAVQI 2918

Query: 1614 EVQNIQYILLKLAEENNNKVKNRISRKTGILLRRKL 1649
              Q  Q    K+ +++  K +   S +  I  + K+
Sbjct: 2919 TSQISQD--AKILDDDREKEEELRSMRADIERQAKI 2952



 Score =  199 bits (505), Expect = 8e-49
 Identities = 337/1714 (19%), Positives = 706/1714 (40%), Gaps = 220/1714 (12%)

Query: 29   LLENLTDIDTKVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDH 88
            L+E     D  +    + IEE+  S     +M  K++ +L K   E Y+    L ++ ++
Sbjct: 557  LIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKEN 616

Query: 89   AMGELRHAHKTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKNERSSEESN 148
             + E++   + + +   N                         R  H  K  E    +  
Sbjct: 617  TLAEIQKEREDLEKMNEN-----------------------ITREMHEIKHQEEQMNQKQ 653

Query: 149  GEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDDRASEAEIQVE 208
             E+  L+  +  +Q + +       +    L   +++L+K Q N   +          +E
Sbjct: 654  DELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDI----------ME 703

Query: 209  ILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIE--AKNLKQELTRVVVQKDT 266
             +K    QL  DK+          E   + + M  ++DN++   K+L ++  ++ +QK  
Sbjct: 704  TMKNERKQLDKDKE----------EMEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQ- 752

Query: 267  VLLQYKQCLEKIPM-LE---NKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEER-- 320
            +  + K  LE++ + LE   ++I+  +E ++    ++E+   E+   +++LA + E+   
Sbjct: 753  MFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIREKESLAHLAEDTKT 812

Query: 321  -----DSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLE-- 373
                 D + V     +  + + ++ +  ++EN  +LK  I+ E EK ++ E     L+  
Sbjct: 813  EKKILDEMKVANESSMADLQREKSILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTE 872

Query: 374  -KSNQNLQLEAENLVQRIASKDHELLEKHTE-IERLQTLMHGEHSNFIQIESALQALQKL 431
             +  QNLQ E  NL +       E + K TE +E  +  +        Q+++ +   Q+ 
Sbjct: 873  VQKQQNLQKEKSNLEEM-----RENISKQTEDVENKKENLRLREDELWQLQAEIYKQQR- 926

Query: 432  YSQSQKEQRNLALELKYGLLLLKD-------LELSKQDFKEEMQGIVEENKTLHELNFSS 484
              + +KE+ N+  E    +  ++D       L+   +  K + +    E + L ++    
Sbjct: 927  --EIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTEL 984

Query: 485  TR---SLKKQQMEISKLKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQAML 541
             R    ++K ++E    ++  E++  +     ++ N L  ET++ KD +  LNE+ + + 
Sbjct: 985  EREADEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNR-KDMV--LNEKNRDIE 1041

Query: 542  EQLQSLGLNPNSFAASVRDLQ---NENFMLKETCKKEHSEKEALREKSKDMNEVLMENAC 598
            ++++S+  + +       DL+   +E + +KE  +K+     A  +K ++  E + EN  
Sbjct: 1042 KKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENIT 1101

Query: 599  MEFSLL-----GLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTL---LSQLQIITE 650
             E   +      +N + D L     EIQ   Q L++EK I+   +S L    S+L     
Sbjct: 1102 REMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQT 1161

Query: 651  SMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEI 710
            +M  I+E      K L   K E E    +  ++E     ++  + +L  +  M+  Q ++
Sbjct: 1162 NMNDIMETMKNERKQLDKDKEEMEE---QKQEMEKERDNMDQSRKSLDEDLKMMKLQKQV 1218

Query: 711  VEEKLSNLEKKVTNLEEKYADVEKDKESAVN--QVEELFASILVQK--------ENHSNH 760
            +EE+ + LE+    LE +  D+ K KE   N  Q+ E  A  L ++        E+    
Sbjct: 1219 IEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAEDTKRE 1278

Query: 761  KHS-SEARLANLENIVRVLQEEQRLGKV---------EFEQELDRVVNAQIEMFILQNCI 810
            K+S  E ++AN  ++  + +E+  L ++         + E+E D++   + E+  LQ  I
Sbjct: 1279 KNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLREDELEQLQAEI 1338

Query: 811  EELELKNF----VLLTECEKLVEASKFSDKVISELESENLMQLIEEEFLLHRIRKFKMDI 866
             + + +        L    ++VE  +  DK+I EL+++ L Q  E       ++K K D+
Sbjct: 1339 HKQQKREIQQEKKKLQSKNQMVELKRQIDKLI-ELKADLLQQQTE-------LKKTKADL 1390

Query: 867  HKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSVLLGS 926
             +     Q+D       +++K    ++ + + + + ++   K  EE Q+   E   L  S
Sbjct: 1391 KQ-----QMD-------DLEKTRKQLAEMSETVTTEQNEYRKLIEELQR---EKEQLEIS 1435

Query: 927  LQQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKENRS 986
              Q + E + L+  K  +E++ E++R +   ++ +K   LE+ R    E+ N + KE   
Sbjct: 1436 KNQIEQEKKDLQNMKSNLERQLESLRHEKANVEDEK-NALEKMRSESKEIQNAIRKERED 1494

Query: 987  KSTLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDV 1046
                  L+   +E+    +  +EE  ++   +  + +  S+L+ ++ + E     + + +
Sbjct: 1495 ------LENCWVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINNKM 1548

Query: 1047 LALSNLNLVYEIFFTENMVEKRA--LCEHLGNLSHLNNDLNQ---------EFGVLRKNF 1095
              L  L +  E+  T+  +EK +  L +   +L +   ++ +         +  +  K  
Sbjct: 1549 EEL--LQMKVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQEKER 1606

Query: 1096 EVK---EAENVYLNESIE----RMDKELLEMDKRLKAAETSNAEFSRHIEELKMEQEEST 1148
            E+K   + E   L+E IE     ++ E+ +M ++ +  E + A   +  EE+K   EE+ 
Sbjct: 1607 EIKIQLDKETKRLSEEIELKVKDLEMEMADMKRQKQEIEDTKAHLEKEKEEMKSITEETR 1666

Query: 1149 KIKENLDRQILEQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLELL 1208
            + KE+L++   +  E   +  K+ + L +  E +  E   L   +++   +      E L
Sbjct: 1667 RQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQVSKQKEEDL 1726

Query: 1209 NKENEFKLWENEAAAFYHDLQMSSICLALLESKVSELTGVCKILD-DESSAKSLENEHMR 1267
             K+ E K                   L   ++++ E+    ++ D  +   K  E E MR
Sbjct: 1727 TKQKEMKEERKS--------------LEETKARIIEMKTKAELEDIKKEKEKEEEEEEMR 1772

Query: 1268 EIISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVIET 1327
              + +   E+  +K          S LK + + ++H          ++    Q    +++
Sbjct: 1773 VKVEMDGKELDRIK----------SELKRERSEIDHEQKKLNDDKKIIEQEKQNLEKMKS 1822

Query: 1328 CLRKHSHQSARENEIV--LIPDGVSDLLTLQTRIRAVEKIMMEELKRRVKQKSLTTESTP 1385
             + K   Q   E   +   I     +   ++     V+K+M+ E++ +  +     E   
Sbjct: 1823 EIMKQRQQMEEERSELENKIKQTYIEKCDIENSKEIVQKLMV-EVEEQKHEIQFQKEELD 1881

Query: 1386 YSSLEIATYPKVENRKKEIELVEENVFDRNSWRKKPKIRLLMKDIPLDRNVDDQNSKYLK 1445
                +IA    +  + K  EL  EN   RN      K R  +K++        +  K + 
Sbjct: 1882 IERQKIADEQDLLIQNKS-ELQNENERIRNLNEIIKKERETLKEMEAHLEKKKEEIKSVS 1940

Query: 1446 REHRRTNDHVLELCENNEHEPLSAPTVDHAMICHRSDDSGRYLNYSSELD-----IEKEL 1500
             E RR  + + ++  +   +          +   R + + ++      +D     I+ +L
Sbjct: 1941 EETRRLKEDLEKMSTDVNKQNKDLMNQRDLLEQEREEINHKWKQLQQRIDEFDAQIKSQL 2000

Query: 1501 GVDKLELSKSVKEKTEDDKRRILERLSSDGQKLAILKMALQDLKKKTETKKKSKQGNDIE 1560
               + E+    K+  +D K    E+   +  K  I+K   Q  ++++E   K KQ  D+E
Sbjct: 2001 ERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQ-TDLE 2059

Query: 1561 YETVKRHIEEVEEAVMQQVSINDQMAKNVEEGASSLDREIPRRGSEQ------IGKLQFE 1614
                +  IE  +E V + +   ++  K++      LD E  +   EQ        KLQ E
Sbjct: 2060 ----RHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNE 2115

Query: 1615 VQNIQYILLKLAEENNNKVKNRISRKTGILLRRK 1648
             + I     K  +E   K K  +      L + K
Sbjct: 2116 NERI-----KEMDEEIKKEKETLKEMEAHLRKEK 2144



 Score =  192 bits (487), Expect = 1e-46
 Identities = 258/1192 (21%), Positives = 516/1192 (42%), Gaps = 129/1192 (10%)

Query: 150  EVQTLREALAKMQSDKDALFLQYQESL---ENLSKMETDLNKAQNNARGLDDRASEAEIQ 206
            E +TL+E  A ++  K+ +    +E+    E+L KM TD+NK QN  + L ++    E +
Sbjct: 1918 ERETLKEMEAHLEKKKEEIKSVSEETRRLKEDLEKMSTDVNK-QN--KDLMNQRDLLEQE 1974

Query: 207  VEILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIEAKNLKQELTRVVVQKDT 266
             E +     QL+   D  +      LE +        +K N + K ++QE   +   K  
Sbjct: 1975 REEINHKWKQLQQRIDEFDAQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSE 2034

Query: 267  VLLQYKQCLEKIPMLENKIALAE------ENSRMLNDQIERTELEVETLRKNLAEMNEER 320
            ++ Q +Q  E+   L+NKI   +      ENS+ +   +++  +EVE  RK++    EE 
Sbjct: 2035 IMKQRQQMEEERSELDNKIKQTDLERHDIENSKEI---VQKLMVEVEEQRKDIRLQKEEL 2091

Query: 321  DSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQ 380
            D         +E+  K+ +E   V +N  +L+N+ E+  E  E  +K +  L++   +L+
Sbjct: 2092 D---------IER-QKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLR 2141

Query: 381  LEAENLVQRIASKDHELLEKHTEIERLQTLMHGEHSNFIQIESALQALQKLYSQSQKEQR 440
             E E +   I        E   ++E++ T ++ ++ + +     L+  ++  +    + +
Sbjct: 2142 KEKEEMRSVIEETQRRQKE---DLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQ 2198

Query: 441  NLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEISKLKE 500
                E    +   K+ +L+KQ   EE      E K+L E          K + E  K+K+
Sbjct: 2199 QRIDEFDAQVSKQKEEDLTKQKKMEE------ERKSLEETKIKIIEMKTKTEPE--KIKK 2250

Query: 501  IKEKLEREF-----HTSTEESNVLQRETHQIKDDIQH----LNERYQAMLEQLQSLGLNP 551
             KEK E E          EE + ++ +  +++ +I H    LN+  + + ++ + L    
Sbjct: 2251 EKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMK 2310

Query: 552  NSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDMNEVLMENACMEFSLLGLNDELD 611
            +      + ++ E   L+   ++ + EK  +    + + ++++E    +  +    +ELD
Sbjct: 2311 SEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELD 2370

Query: 612  GLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESMQKILENNTVLEKSLSDAKI 671
              R  + + Q    +L + KS L +E   + +  ++I +  + + E    LEK   + K 
Sbjct: 2371 IERQKIADEQD---LLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKS 2427

Query: 672  EFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLE----- 726
              E  R +  DLE     +N++K +L+++R +L  + E +  K   L++++   +     
Sbjct: 2428 ITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSK 2487

Query: 727  EKYADVEKDKESAVNQ--VEELFASILVQKENHSNHKHSSEARLANLENIVRVLQEEQRL 784
            +K  D+ K+KE   ++  +EE  A+IL  K      +   E      E  +RV       
Sbjct: 2488 QKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQEMRV------- 2540

Query: 785  GKVEFEQELDRVVNAQIEMFILQNCIEELELKNFVLLTECEKLVEASKFSDKVISELESE 844
             KVE E++    + +Q+E    +   E+ +L +   + E EK     +  +K+ SE+  +
Sbjct: 2541 -KVEMERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEK-----EDLEKMKSEIMKQ 2594

Query: 845  NLMQLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLES 904
                  E   L  +I++  ++ H +    +I      + E +K EI   +     E L+ 
Sbjct: 2595 RQQMEEERSELDKKIKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQK-----EELDI 2649

Query: 905  SLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVE 964
               K  +E Q LL++N +      + Q+E E++K   + +++E E ++E  V LQK+K E
Sbjct: 2650 ERQKIADE-QDLLIQNKI------EQQNENERIKEMDEEIKKERETLKEMEVNLQKEKEE 2702

Query: 965  L---LEENRQLRIEVVNGVEKENRSKS------------------TLAALQAEMIELRQT 1003
            +   +EE ++ + ++       N  K                    L  LQ  + E   T
Sbjct: 2703 IESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFETT 2762

Query: 1004 NQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVLALSNLNLVYEIFFTEN 1063
            N   Q+E  K  + KN L R  S+L   K+  + +   M      + +     E    E 
Sbjct: 2763 N--LQKEKNKTEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNEL 2820

Query: 1064 MVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVK-----------EAENVYLNESIERM 1112
              EK+++   L    H  + L  E    +++ E +           E++   L+ +IE+M
Sbjct: 2821 EDEKKSMLSRLSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKM 2880

Query: 1113 DKELLEMDKRLKAAETSNAEFSRHIEELKMEQEESTKIKENLDRQILEQSENCMNHKKEI 1172
            + + L + +   + E   A+  R  E+L  E  ++ +I      QI + ++   + +++ 
Sbjct: 2881 NMDKLSIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITS----QISQDAKILDDDREKE 2936

Query: 1173 EHLNEANETLQFEMKTLLHEVEQHRVREEALNLELLNKENEFKLWENEAAAFYHDLQMSS 1232
            E L      ++ + K L  +V+  +  +E   LE    EN+    + E     +DL +  
Sbjct: 2937 EELRSMRADIERQAKILESDVQLLQTEKEI--LEKSKTENDLLREDLEKQRKRNDLTLQE 2994

Query: 1233 ICLALLESKVSELTGVCKILDDESSAKSLENEHMREIISLLESEIGGLKEQL 1284
                L + K++    +  I  ++ +  SL+NE     +SL + E+   + +L
Sbjct: 2995 ----LRKEKMALEQMITDITKEKDAVASLQNE-----VSLKQHELKNKETEL 3037



 Score =  183 bits (465), Expect = 3e-44
 Identities = 307/1650 (18%), Positives = 689/1650 (41%), Gaps = 249/1650 (15%)

Query: 136  RSKKNERSSEESNGEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARG 195
            RS+ + R SE    +   + + +  M++++  L    +E+ E   +ME + +    + + 
Sbjct: 24   RSQLDLRQSELDKQQTN-MNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKS 82

Query: 196  LDDRASEAEIQVEILKES-----LMQLKADKDAGEV------------LYNQCLETIARL 238
            LD+     ++Q ++++E       M+++ +++A E+            ++ +  E + + 
Sbjct: 83   LDEDLKMMKLQKQVIEEEKSKLKQMKIELEREADEIRKVKEETQNERQIFEKMTEALKKE 142

Query: 239  ESMLSQKDNIEAKNLKQELTRVVVQKDTVLL--------------QYKQCLEKIPMLENK 284
               LS+    +AK   Q L  + V  ++ L                  +  E +   + K
Sbjct: 143  REDLSE----DAKRKNQVLDEMKVANESTLADILRERSNLQEMRENISKQTEDVENKKEK 198

Query: 285  IALAEENSRMLNDQIERTELE------------------VETLRKNLAEMNEERDSLSV- 325
            I L EE  + L  +I + + E                  VE L+  +  ++ + +SL + 
Sbjct: 199  IRLREEKLKQLQAEIHKQQSETEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLD 258

Query: 326  --LYHHCLEKISKMENEILHVQENAEQLKNKIEKE--------AEKLEISEKHRGMLEKS 375
               + +  E++ +M+ E+    +  E++K + + E        A+ +E     R  L K+
Sbjct: 259  REAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLNKN 318

Query: 376  NQNLQLEAENLVQRIASKD--HELLEKHTEIERLQTLMHGEHSN-----FIQIESALQAL 428
             + +Q + + + +     D   + L+K+ ++ +LQ  +  E  N      I++E     +
Sbjct: 319  KEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMKIELEKEADEI 378

Query: 429  QKLYSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSL 488
            +K+  ++Q E++ L         + ++L+  K+ F    +    E K L ++  ++   +
Sbjct: 379  RKIKEETQNERQRLE-------KMTEELKKEKESFTHLAEDTKTEKKILDKMKVANESLM 431

Query: 489  KKQQMEISKLKEIKEKLEREFHTSTEESNVL---QRETHQIKDDIQHLNERYQAMLEQLQ 545
               Q E S L+E++E + ++   S +E   +   + E  Q++ +I    ++ +  +E+  
Sbjct: 432  ADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLREDELEQLQAEIH--KQQGEIKMEKSN 489

Query: 546  SLGLNPNSFAASVRDLQNENFMLKE-------------------------------TCKK 574
            +   +  S        +NE  +LK+                                 +K
Sbjct: 490  NENRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQIQK 549

Query: 575  EHSEKEALREKSKDMNEVLME-NACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSI 633
            +  E   L E++   + VL E N  +E  +  +  + D L     ++++    L + K  
Sbjct: 550  DRDEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKED 609

Query: 634  LADEKSTLLSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDE 693
            L  +K   L+++Q   E ++K+ EN T   + + + K + E +  K  +L+     L  E
Sbjct: 610  LEKQKENTLAEIQKEREDLEKMNENIT---REMHEIKHQEEQMNQKQDELDQ----LKTE 662

Query: 694  KNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASILVQ 753
              NLQ E   L  + EI+ +  S L+ + + L+++  ++    E+  N+ ++L       
Sbjct: 663  IQNLQQE---LEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDK----D 715

Query: 754  KENHSNHKHSSEARLANLENIVRVLQEEQ---RLGKVEFEQELDRVVNAQIEMFILQNCI 810
            KE     K   E    N++   + L E+Q   +L K  FE+E +++   +IE        
Sbjct: 716  KEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIE-------- 767

Query: 811  EELELKNFVLLTECEKLVEASKFSDKVISELESENLMQLIEEEFLLHRIRKFKMDIHKVC 870
                     L  E +++ +  + +      LE      + E+E L H     K +  K+ 
Sbjct: 768  ---------LEREADEISKIKEETQNKRQRLEKMTEELIREKESLAHLAEDTKTE-KKIL 817

Query: 871  GVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSVLLGSLQQH 930
              +++ ++     ++++E+  +  + + I  L+   + +++E  +L  +    L  LQ  
Sbjct: 818  DEMKVANE-SSMADLQREKSILEEMRENISKLK-EYIDNEKEKSKLREDE---LKKLQTE 872

Query: 931  QSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKENRSKSTL 990
              + + L+ EK  +E+    MRE N+  Q + VE  +EN +LR             +  L
Sbjct: 873  VQKQQNLQKEKSNLEE----MRE-NISKQTEDVENKKENLRLR-------------EDEL 914

Query: 991  AALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVLALS 1050
              LQAE+ + ++     ++E   +  E+ ++ +NV DL+    S + ++  +  D  A  
Sbjct: 915  WQLQAEIYKQQRE---IEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFE 971

Query: 1051 NLNLVYEIFFTE-----NMVEKRAL-CEH-LGNLSHLNNDLNQEFGVLRKNFEVKEAENV 1103
            N   V +   TE     + +EK  L  +H    +  +   + ++   +    E    +++
Sbjct: 972  NEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDM 1031

Query: 1104 YLNESIERMDKELLEMDKRLKAAETSNAEFSRHIEELKMEQEESTKIKENLDRQILEQSE 1163
             LNE          +++K++K+ ++      +   +L+  + E  K+KE+L++    Q E
Sbjct: 1032 VLNEKNR-------DIEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEK----QKE 1080

Query: 1164 NCMNH-KKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLELLNKENEFKLWENEAA 1222
            N +   +KE E L + NE +  EM  + H+ EQ   +++ L+      +N  +  E E  
Sbjct: 1081 NTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKE 1140

Query: 1223 AFYHDLQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMREIISLLESEIGGLKE 1282
                         + L+ + + +  + + + +E      + E M E    +E E   + +
Sbjct: 1141 IIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQ 1200

Query: 1283 QLSAYVPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVIETCLRKHSHQSARENEI 1342
                      SL ED   ++                 QK V+ E   +    +   E E 
Sbjct: 1201 SR-------KSLDEDLKMMK----------------LQKQVIEEEKNKLEQMKIELERE- 1236

Query: 1343 VLIPDGVSDLLTLQTRIRAVEKIMMEELKRRVKQKSLTTEST-----PYSSLEIATYPKV 1397
                D +  +       R + + M EELK+  K  +   E T         +++A    +
Sbjct: 1237 ---ADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAEDTKREKNSLDEMKVANESSM 1293

Query: 1398 ENRKKE---IELVEENVFDRNS--WRKKPKIRLLMKDI-PLDRNVDDQNSKYLKREHRR- 1450
             + +KE   +E ++EN+  +     ++K KIRL   ++  L   +  Q  + +++E ++ 
Sbjct: 1294 ADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQQKREIQQEKKKL 1353

Query: 1451 -TNDHVLELCENNEHEPLSAPTVDHAMICHRSDDSGRYLNYSSELDIEKELGVDKLELSK 1509
             + + ++EL    + + L     D  ++  +++      +   ++D  ++      E+S+
Sbjct: 1354 QSKNQMVEL--KRQIDKLIELKAD--LLQQQTELKKTKADLKQQMDDLEKTRKQLAEMSE 1409

Query: 1510 SVKEKTEDDKRRILERLSSDGQKLAILKMALQDLKKKTETKKKSKQGNDIEYETVKRHIE 1569
            +V  + +++ R+++E L  + ++L I K  ++  KK  +  K + +         K ++E
Sbjct: 1410 TVTTE-QNEYRKLIEELQREKEQLEISKNQIEQEKKDLQNMKSNLERQLESLRHEKANVE 1468

Query: 1570 EVEEAVMQQVSINDQMAKNVEEGASSLDR---EI---PRRGSEQIGKLQFEVQNIQYI-- 1621
            + + A+ +  S + ++   + +    L+    EI    +R  E+  +L+   + I+ +  
Sbjct: 1469 DEKNALEKMRSESKEIQNAIRKEREDLENCWVEIEGEKKRMEEETRRLEMHREEIKKVDS 1528

Query: 1622 LLKLAEENNNKVKNRISRKTGILLRRKLRV 1651
             L+ + EN    + +I+ K   LL+ K+ +
Sbjct: 1529 ELQKSRENIESREEKINNKMEELLQMKVEM 1558



 Score =  141 bits (355), Expect = 2e-31
 Identities = 271/1279 (21%), Positives = 535/1279 (41%), Gaps = 168/1279 (13%)

Query: 420  QIESALQALQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHE 479
            Q+++ +Q LQ    Q  ++++ + ++ +   L L+  EL KQ  +  M  I+E  K    
Sbjct: 1    QLKTEIQNLQ----QELEKEKEIIMKAR-SQLDLRQSELDKQ--QTNMNDIMETMK---- 49

Query: 480  LNFSSTRSLKKQQMEISKLKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQA 539
               +  + L K + E    +E K+++E+E H   +    L  +   +K   Q + E    
Sbjct: 50   ---NERKQLDKDKEET---EEQKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVIEEEKSK 103

Query: 540  MLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDMNEVLME-NAC 598
            + +    L    +       + QNE  + ++  +    E+E L E +K  N+VL E    
Sbjct: 104  LKQMKIELEREADEIRKVKEETQNERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVA 163

Query: 599  MEFSLLGLNDELDGLRGTVKEIQQFCQVLQ--EEKSILADEKSTLLSQLQIITESMQKIL 656
             E +L  +  E   L+   + I +  + ++  +EK  L +EK   L QLQ      Q   
Sbjct: 164  NESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLREEK---LKQLQAEIHKQQSET 220

Query: 657  E-NNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVEEKL 715
            E   + +E+  +    + E L+ K   L+   + L  ++   +NE+  L      +E + 
Sbjct: 221  EKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELEREA 280

Query: 716  SNLEK-------KVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHSNHKHSSEARL 768
              +EK       +   +EE  AD  +   +   Q+ +    +  QK+     +H  +   
Sbjct: 281  DEIEKIKLETQHERQRVEEMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSR 340

Query: 769  ANLENIVRVL--------QEEQRLG--KVEFEQELDRVVNAQIEMFILQNCIEELELKNF 818
             +L+  ++++        +E+ +L   K+E E+E D +   + E    QN  + LE    
Sbjct: 341  KSLDKNLKMMKLQKQVIEEEKNKLEQMKIELEKEADEIRKIKEE---TQNERQRLEKMTE 397

Query: 819  VLLTECEK---LVEASKFSDKVISELESENLMQLIEEEFLLHRIRKFKMDIHKVCGVLQI 875
             L  E E    L E +K   K++ +++  N       E L+  ++K K ++ ++   +  
Sbjct: 398  ELKKEKESFTHLAEDTKTEKKILDKMKVAN-------ESLMADLQKEKSNLEEMRENISK 450

Query: 876  DSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVEN-----SVLLGSLQQH 930
             ++   D+E +KE+I +    D++E L++ + K Q E +     N       L    +  
Sbjct: 451  QTE---DSEKEKEKIRLRE--DELEQLQAEIHKQQGEIKMEKSNNENRDAESLKLDREAF 505

Query: 931  QSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQL---RIEVVNGVEKENRSK 987
            ++E E LK  K  +E+E + + +  +  Q D+  + E   Q+   R E+ N +E+ NR  
Sbjct: 506  ENEKEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKD 565

Query: 988  STLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDV- 1046
                 L  +  ++ +  +  Q +   +  EK+ L +  S+L   K   E +      ++ 
Sbjct: 566  ---MVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQ 622

Query: 1047 -----LALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAE 1101
                 L   N N+  E+   ++  E+  + +    L  L  ++      L K  E+   +
Sbjct: 623  KEREDLEKMNENITREMHEIKHQEEQ--MNQKQDELDQLKTEIQNLQQELEKEKEIIMKD 680

Query: 1102 NVYLNESIERMDKELLEMDKRLKAAETSNAEFSRHIEELKMEQEESTKIKENLD--RQIL 1159
               L+     +DK+   M+  ++  +    +  +  EE++ +++E  K ++N+D  R+ L
Sbjct: 681  RSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSL 740

Query: 1160 EQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALN-LELLNKENEFKLWE 1218
            ++ +  M  +K++    E N+  Q +++      E  +++EE  N  + L K  E  + E
Sbjct: 741  DEDQKKMKLQKQMFE-EEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIRE 799

Query: 1219 NEAAAFYHDLQMSSICLALLESKVSELTGVCKILDD-----ESSAKSLEN-----EHMRE 1268
             E+ A             L E   +E     KILD+     ESS   L+      E MRE
Sbjct: 800  KESLAH------------LAEDTKTEK----KILDEMKVANESSMADLQREKSILEEMRE 843

Query: 1269 IISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVIETC 1328
             IS L+  I   KE+        S L+ED   L+ +     K+ ++     QK+      
Sbjct: 844  NISKLKEYIDNEKEK--------SKLRED--ELKKLQTEVQKQQNL-----QKE------ 882

Query: 1329 LRKHSHQSARENEIVLIPDGVSDLLTLQTRIRAVEKIMMEELKRRVKQKSLTTESTPYSS 1388
              K + +  REN      D  +    L+ R   + ++  E  K   +Q+ +  E     S
Sbjct: 883  --KSNLEEMRENISKQTEDVENKKENLRLREDELWQLQAEIYK---QQREIEKEKINIES 937

Query: 1389 LEIATYPKVENRKKEIELVEEN----VFDRNSWRKKPKIRLLMKDIPLDRNVDDQNSKYL 1444
               A    VE+ + +I  ++ +      DR ++  + ++   MK   L+R  D+     L
Sbjct: 938  ERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMK-TELEREADEIEKIKL 996

Query: 1445 KREHRRTNDHVLELCENNEHEPLSAPTVDHAMICHRSDDSGRYLNYSSELDIEKELGVDK 1504
            + +H R     +      + + ++        +   ++     LN  +  DIEK+  +  
Sbjct: 997  ETQHDRQRVEEMTAQIQKDRDKIN-------NLIEETNRKDMVLNEKNR-DIEKK--IKS 1046

Query: 1505 LELSKSVKEKTEDDKRRILERLSSDGQKLAILKMALQDLKKKTET--KKKSKQGNDIE-- 1560
            ++  K + EK + D    LE+  S+  K+       +DL+K+ E    +  K+  D+E  
Sbjct: 1047 IQSDKDMLEKEKHD----LEKTRSELYKVK------EDLEKQKENTLAQIQKEREDLEKM 1096

Query: 1561 YETVKRHIEEV---EEAVMQQVSINDQMAKNVEEGASSL--DREIPRRGSEQIGKLQFEV 1615
             E + R + E+   EE + Q+    DQ+   ++     L  ++EI  +   Q+ + Q E+
Sbjct: 1097 NENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSEL 1156

Query: 1616 QNIQYILLKLAEENNNKVK 1634
               Q  +  + E   N+ K
Sbjct: 1157 DKQQTNMNDIMETMKNERK 1175



 Score =  132 bits (331), Expect = 1e-28
 Identities = 233/1237 (18%), Positives = 515/1237 (40%), Gaps = 174/1237 (14%)

Query: 488  LKKQQMEISKLKEIKEKLEREFHTSTEESNVLQRETHQI----KDDIQHLNERYQAMLEQ 543
            ++  Q E+ K KEI  K   +      E +  Q   + I    K++ + L++  +   EQ
Sbjct: 6    IQNLQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQ 65

Query: 544  LQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDMNEVLMENACMEFSL 603
             Q +    + F  S + L  +  M+K        +K+ + E+   + ++ +E       +
Sbjct: 66   KQEMEKEKHDFDQSRKSLDEDLKMMK-------LQKQVIEEEKSKLKQMKIELEREADEI 118

Query: 604  LGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITES-----------M 652
              + +E    R   +++ +  +  +E+ S  A  K+ +L ++++  ES           +
Sbjct: 119  RKVKEETQNERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANESTLADILRERSNL 178

Query: 653  QKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVE 712
            Q++ EN   + K   D + + E +R++   L+     ++ +++  + E+S +  +   + 
Sbjct: 179  QEMREN---ISKQTEDVENKKEKIRLREEKLKQLQAEIHKQQSETEKEKSNIERERAAII 235

Query: 713  EKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHSNHKHSSEARLANLE 772
            + + +L+ K+ +L+     ++ D+E+  N+ EEL              K   E     +E
Sbjct: 236  KDVEDLQSKIISLDRDAESLKLDREAFENEKEEL-----------KQMKTELEREADEIE 284

Query: 773  NIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQNCIEELELKNFVLLTECEKLVEASK 832
             I    Q E++  +VE E   D +     E   L    EE++ +   +  E   + ++ K
Sbjct: 285  KIKLETQHERQ--RVE-EMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRK 341

Query: 833  FSDKVISELESENLMQLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPI 892
              DK +  ++ +   Q+IEEE   +++ + K+++ K              +EI+K +   
Sbjct: 342  SLDKNLKMMKLQK--QVIEEE--KNKLEQMKIELEKEA------------DEIRKIKEET 385

Query: 893  SRILDKIESLESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMR 952
                 ++E +   L K +E    L  +       L + +   E L  + +  +   E MR
Sbjct: 386  QNERQRLEKMTEELKKEKESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMR 445

Query: 953  EQNVILQKDKVELLEENRQLRIEVVNGVEKENRSKSTLAALQAEMIELRQTNQVFQEENG 1012
            E N+  Q +  E  +E  +LR             +  L  LQAE         + +++  
Sbjct: 446  E-NISKQTEDSEKEKEKIRLR-------------EDELEQLQAE---------IHKQQGE 482

Query: 1013 KMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVLALSNLNLVYEIFFTENMVEKRALCE 1072
              +++ N+  R+   LK  + + E+E  V+      L       E    E   +++ + E
Sbjct: 483  IKMEKSNNENRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKIKLETQHDRQRVEE 542

Query: 1073 HLGNLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIE--RMDKELLEMDKR-------- 1122
                +    +++N       +   V   +N  + E I+  + DK++LE +K         
Sbjct: 543  MAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSE 602

Query: 1123 -LKAAETSNAEFSRHIEELKMEQEESTKIKENLDRQI--LEQSENCMNHKK-EIEHLNEA 1178
              K  E    +    + E++ E+E+  K+ EN+ R++  ++  E  MN K+ E++ L   
Sbjct: 603  LYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTE 662

Query: 1179 NETLQFEM----KTLLHEVEQHRVREEALNLELLNKENEFKLWENEAAAFYHDLQMSSIC 1234
             + LQ E+    + ++ +  Q  +R+  L+ +  N  +  +  +NE      D +     
Sbjct: 663  IQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQ 722

Query: 1235 LALLESKVSELTGVCKILDDESSAKSLENEHMREIISLLESEIGGLKEQLSAYVPLVSSL 1294
               +E +   +    K LD++     L+ +   E  + LE     +K +L      +S +
Sbjct: 723  KQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQ----MKIELEREADEISKI 778

Query: 1295 KEDFNS----LEHISLLWTKRNSVVGNGA-----QKDVVIETCLRKHSHQSARENEIVLI 1345
            KE+  +    LE ++    +    + + A     +K ++ E  +   S  +  + E  ++
Sbjct: 779  KEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSIL 838

Query: 1346 PDGVSDLLTLQTRI---RAVEKIMMEELKRR----VKQKSLTTESTPYSSLE---IATYP 1395
             +   ++  L+  I   +   K+  +ELK+      KQ++L  E +    +         
Sbjct: 839  EEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQNLQKEKSNLEEMRENISKQTE 898

Query: 1396 KVENRKKEIELVEENVFDRNSWRKKPKIRLLMKDIPLDR-NVDDQNSKYLKREHRRTNDH 1454
             VEN+K+ + L E+ +     W+ + +I    ++I  ++ N++ + +  +K         
Sbjct: 899  DVENKKENLRLREDEL-----WQLQAEIYKQQREIEKEKINIESERAAIIKN-------- 945

Query: 1455 VLELCENNEHEPLSAPTVDHAMICHR-SDDSGRYLNYSSELDIEKELGVDKLELSKSVKE 1513
                 E+ +H+ +S      ++   R + ++ R +    + ++E+E   D++E    +K 
Sbjct: 946  ----VEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELERE--ADEIE---KIKL 996

Query: 1514 KTEDDKRRILE---RLSSDGQKLAIL-------KMALQDLKKKTETKKKS---------K 1554
            +T+ D++R+ E   ++  D  K+  L        M L +  +  E K KS         K
Sbjct: 997  ETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIKSIQSDKDMLEK 1056

Query: 1555 QGNDI-----EYETVKRHIEEVEEAVMQQVSINDQMAKNVEEGASSLDREIP------RR 1603
            + +D+     E   VK  +E+ +E  + Q+    +  + + E  +    EI        +
Sbjct: 1057 EKHDLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQ 1116

Query: 1604 GSEQIGKLQFEVQNIQYILLKLAEENNNKVKNRISRK 1640
              +++ +L+ E+QN+Q  L K  +E   K ++++ R+
Sbjct: 1117 KQDELDQLKTEIQNLQQELEK-EKEIIMKARSQLDRR 1152



 Score = 53.1 bits (126), Expect = 7e-05
 Identities = 73/385 (18%), Positives = 164/385 (41%), Gaps = 38/385 (9%)

Query: 39   KVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHAMGELRHAHK 98
            ++K M + I++E ++         K++ E+  ++EE  R    L E+    + E +    
Sbjct: 2674 RIKEMDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDL-EKMSTDINEQKQDLM 2732

Query: 99   TMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKNERSSEESNGEVQTLREAL 158
               +        + +  +       + E+    +  +++++ +   E    E+   +  +
Sbjct: 2733 NQRDLLKQEREEMNHKLTQLQQRIDEFETTNLQKEKNKTEELKNILEREKSELYQEKAQV 2792

Query: 159  AKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARG--------LDDRASEAEIQVEIL 210
             + + + + +    +  +ENL  +  +L   + +           +D   +E + + E +
Sbjct: 2793 QQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSRLSMEKHEIDKLKTEIQSEKESI 2852

Query: 211  KESLMQLKADKDAGEVLYNQCLETIARLE----SMLSQKDNIEAKNLKQELTRVVVQKDT 266
            +E    LK  KD  E    Q   TI ++     S+  +KD++E   +K +L R   + D 
Sbjct: 2853 EEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLSIQREKDSLE--EIKADLQRKAEKLDE 2910

Query: 267  VLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNL---AEMNEERDSL 323
             + +  Q   +I           +++++L+D  E+ E E+ ++R ++   A++ E    L
Sbjct: 2911 EMRKAVQITSQI----------SQDAKILDDDREKEE-ELRSMRADIERQAKILESDVQL 2959

Query: 324  SVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQLEA 383
                   LEK SK EN++L      E L+ + ++    L+   K +  LE+   ++  E 
Sbjct: 2960 LQTEKEILEK-SKTENDLLR-----EDLEKQRKRNDLTLQELRKEKMALEQMITDITKEK 3013

Query: 384  E---NLVQRIASKDHELLEKHTEIE 405
            +   +L   ++ K HEL  K TE++
Sbjct: 3014 DAVASLQNEVSLKQHELKNKETELD 3038



 Score = 42.4 bits (98), Expect = 0.12
 Identities = 61/311 (19%), Positives = 127/311 (40%), Gaps = 34/311 (10%)

Query: 32   NLTDIDTKVKSMIKLIE-EEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHAM 90
            NL     K + +  ++E E+++ +  +A++  +K       +E   +  ++  E  +   
Sbjct: 2763 NLQKEKNKTEELKNILEREKSELYQEKAQVQQQKHE-----METIRKTMKSEMENLECLR 2817

Query: 91   GELRHAHKTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKNERSSEES--N 148
             EL    K+M        + I   D     +  + ES    + T +  K+E  S+ +  +
Sbjct: 2818 NELEDEKKSMLSRLSMEKHEI---DKLKTEIQSEKESIEEEKKTLKQLKDENESKRTQLD 2874

Query: 149  GEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKA-------QNNARGLDD--- 198
              ++ +      +Q +KD+L     +      K++ ++ KA         +A+ LDD   
Sbjct: 2875 NTIEKMNMDKLSIQREKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDRE 2934

Query: 199  -----RASEAEI--QVEILKESLMQLKADKDAGEV------LYNQCLETIARLESMLSQK 245
                 R+  A+I  Q +IL+  +  L+ +K+  E       L  + LE   +   +  Q+
Sbjct: 2935 KEEELRSMRADIERQAKILESDVQLLQTEKEILEKSKTENDLLREDLEKQRKRNDLTLQE 2994

Query: 246  DNIEAKNLKQELTRVVVQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELE 305
               E   L+Q +T +  +KD V     +   K   L+NK    +E  + ++D   + E+ 
Sbjct: 2995 LRKEKMALEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMR 3054

Query: 306  VETLRKNLAEM 316
              +  K   E+
Sbjct: 3055 QNSTNKQQQEV 3065


>UniRef100_UPI000043732F UPI000043732F UniRef100 entry
          Length = 1970

 Score =  204 bits (520), Expect = 1e-50
 Identities = 326/1681 (19%), Positives = 702/1681 (41%), Gaps = 234/1681 (13%)

Query: 29   LLENLTDIDTKVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDH 88
            L+E     D  +    + IEE+  S     +M  K++  L K   E Y+    L ++ ++
Sbjct: 419  LIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLEKQKEN 478

Query: 89   AMGELRHAHKTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKNERSSEESN 148
             + E++   + + +   N                   E H       + K+ +   ++  
Sbjct: 479  TLAEIQKEREDLEKMNENIT----------------IEMHEIKHQEEQMKQKQDELDQLK 522

Query: 149  GEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDDRASEAEIQVE 208
             E+Q L++ L K   +K+ +     E    L   +++L+K Q N   +          +E
Sbjct: 523  TEIQNLQQELEK---EKEIIMKDRSE----LDLRQSELDKQQTNMNDI----------IE 565

Query: 209  ILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIE--AKNLKQELTRVVVQKDT 266
             +K     L  DK+          E   + + M  ++DN++   K+L ++L  + +QK  
Sbjct: 566  TMKNERKLLDKDKE----------EMEEQKQEMEKERDNMDQSIKSLDEDLKMMKLQKQV 615

Query: 267  VLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEERDSLSVL 326
            +    ++   K+  ++ ++    +  R + ++ +     +E + K L  + E  D + + 
Sbjct: 616  I----EEEKNKLEQMKFELQREADEIRKIKEETQNERQSLEKMTKAL--IKEREDLMKIE 669

Query: 327  YHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQLEAENL 386
                 ++ISK++ E  + ++  E++  ++ +E E L    +     +K    +++  E+ 
Sbjct: 670  LEREADEISKIKEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESS 729

Query: 387  VQRIASKDHELLEKHTEIERLQTLMHGEHSNFIQIESALQAL----QKLYSQSQKEQRNL 442
            +  +  +   L E    I +L+  +  E       E  L+ L    QK  S+   E+ N+
Sbjct: 730  MADLQREKSILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNI 789

Query: 443  ALE----LKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEISKL 498
              E    ++    ++ +L+   +D + +M+ I+ E + LH      TR ++  Q ++  L
Sbjct: 790  ESERAAMIREKQNMMTELKKKSEDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDL 849

Query: 499  KEIKE--KLEREFHTSTEES--------NVLQRETHQIKDDIQHLNERYQAMLEQLQSLG 548
            +   +  KL+RE   + +E+         +   E  +IK + QH  +R + M  Q+Q   
Sbjct: 850  ERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQ--- 906

Query: 549  LNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDMNEVLMENACMEFSLLGLND 608
                      ++    N +++ET +K+      L EK++D+ E           +  +  
Sbjct: 907  ----------KERDKINNLIEETNRKD----MVLNEKNRDIEE----------KIKSIQS 942

Query: 609  ELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESMQKILENNTVLEKSLSD 668
            + D L      +++    L + K  L  +K   L+++Q   E ++K+ EN T   + + +
Sbjct: 943  DKDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKMNENIT---REMHE 999

Query: 669  AKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEEK 728
             K + E +  K  +L+     + + +  L+ E+ +++      + + S L+K+ TN+ + 
Sbjct: 1000 IKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQFDLRQSELDKQQTNMNDI 1059

Query: 729  YADVEKDKESAVNQVEELFASILVQKENHSNHKHSSEARLANLENIVRVLQEEQRLGKVE 788
               ++ +++      EE+      QK+     KH  +    +L+  ++++    +L K  
Sbjct: 1060 METMKNERKQLDKDKEEMEE----QKQEMEKEKHDFDQSRKSLDKDLKMM----KLQKQV 1111

Query: 789  FEQELDRVVNAQIEMFILQNCIEELELKNFVLLTECEKLVEASKFSDKVISELESENLMQ 848
            FE+E +++   +IE+    + I +++ +        EK+ E  K   +  + L  +    
Sbjct: 1112 FEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESFTHLAEDTKK- 1170

Query: 849  LIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVK 908
              E+E L     K K+    +   LQ +      + +++    IS+  + +E+ + +L  
Sbjct: 1171 --EQEIL----DKVKVANESLMADLQKEK-----SNLEEMRENISKQTEDVENKKENLRL 1219

Query: 909  SQEENQQLLVENSVLLGSLQQHQSEGEKLKLEK-KTVEQEFENMREQNVILQKDKVELLE 967
             ++E  QL  E        QQ + E EK+ +EK +  +QE E+MRE   ILQK+K    E
Sbjct: 1220 REDELWQLQAEI-----YKQQREIEKEKINIEKLEEKQQEEESMRE---ILQKEK----E 1267

Query: 968  ENRQLRIEVVNGVEKENRSKSTLAALQAEMIELRQTNQVFQEENGKMLD---EKNSLCRN 1024
            E  QL+ ++       NR K  +  +  E++E    +++++ E     D    K  L   
Sbjct: 1268 ELEQLKKDI-------NREKEDI-EISRELVE----SEIYEGEVKGFTDVQKYKEELQIV 1315

Query: 1025 VSDLKDAKSSAEDENSVMFHDVLALSNLNLVY------------EIFFTENMVEKRA--- 1069
              +L   K + E  NS + H +  L  +++ Y            EI   E ++EK+    
Sbjct: 1316 TEELLTKKRNLEQLNSDVQHLMQTLEEVDIQYIKKKAELEHITSEIQKREQILEKQKKKL 1375

Query: 1070 -----LCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIERMDKELLEMDKRLK 1124
                 + E +  +      +N E    R++ E KE EN+      E+ + EL  +    +
Sbjct: 1376 EENGWIIEEIEMMKVTLESINMEILQKREDME-KEKENL----RREKQETELFRVKNERE 1430

Query: 1125 AAETSNAEFSRHIEELKMEQEESTKIKENLD----------------RQILEQSENCMNH 1168
              + + A   R  +E+K   EE+++ KE+L+                +  LEQ    +NH
Sbjct: 1431 TLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINH 1490

Query: 1169 K-----KEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLELLNKENEFKLWENEAAA 1223
            K     + I+  +      + E  T   ++E+ R   E +N +++  + + +L  +E   
Sbjct: 1491 KWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQ 1550

Query: 1224 FYHDLQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMREIISLLESEIGGLKEQ 1283
               +LQ     +   + K   +T   K+  +      +++E +RE     ++E+   +++
Sbjct: 1551 KIEELQTLQEQIMKEKEKAEAMT--IKLKMEREDLDQIKSELVRE-----KTEVDHEQKK 1603

Query: 1284 LSAYVPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVI-ETCLRKHSHQSARENEI 1342
            L+  + ++   KED   ++  S + T++  +    ++ D  I +T L KH  + ++E   
Sbjct: 1604 LNDDIKMIEQEKEDLEKMK--SEIMTQKQEMEKERSELDNKIQQTDLEKHDIEKSKE--- 1658

Query: 1343 VLIPDGVSDLLTLQTRIRAVEKIMMEELKRRVKQKSLTTESTPYSSLEIATYPKVENRKK 1402
                               VEK+M E  ++R  +  L  E       +IA    +  + K
Sbjct: 1659 ------------------IVEKLMFEVEEQR-HEIQLQKEELDIERQKIADEQDLLIQNK 1699

Query: 1403 EIELVEENVFDRNSWRKKPKIRLLMKDIPLDRNVDDQNSKYLKREHRRTNDHVLELCENN 1462
              EL  EN   RN      K R  +K++      + +  K +  E RR  + + ++  + 
Sbjct: 1700 S-ELQNENERIRNINEVIKKERETLKEMEAHLEKEKEEMKSITEETRRQKEDLEKMSTDI 1758

Query: 1463 EHEPLSAPTVDHAMICHRSDDSGRYLNYSSELDIEKELGVDKLELSKSVKEKTEDDKRRI 1522
            + +          +   + D +  +      +D E +  V K +     K+K   ++R+ 
Sbjct: 1759 KEQNQDLMKQRDLLEQEKEDINHEWTQLQQRID-EFDAQVSKQKEEDLTKQKEMKEERKS 1817

Query: 1523 LERLSSDGQKLAILKMALQDLKKKTETKKKSKQGNDIEYETVKRHIEEVEEAVMQQVSIN 1582
            LE   +   ++   K  L+D+KK+ E K++ ++   ++ E   + ++ ++  + ++ S  
Sbjct: 1818 LEETKARIIEMK-TKAELEDIKKEKE-KEEEEEEMRVKVEMDGKELDRIKSELKRERSEI 1875

Query: 1583 DQMAKNVEEGASSLDREIPRRGSEQIGKLQFEVQNIQYILLKLAEENNNKVKNRISRKTG 1642
            D   K + +     D++I  +  + + K++ E+   +  + +   E  NK+K     K  
Sbjct: 1876 DHEQKKLND-----DKKIIEQEKQNLEKMKSEIMKQRQQMEEERSELENKIKQTYIEKCD 1930

Query: 1643 I 1643
            I
Sbjct: 1931 I 1931



 Score =  202 bits (513), Expect = 9e-50
 Identities = 342/1661 (20%), Positives = 707/1661 (41%), Gaps = 234/1661 (14%)

Query: 35   DIDTKVKSMIKLIEE---EADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHAMG 91
            +I  + +S+ K+ EE   E +SF   AE   KK  E++  ++    +  A  ++      
Sbjct: 226  EIQNERQSLEKMTEELKREKESFTHLAEDT-KKEQEILDEIKVANESLMAELQKEKSNFE 284

Query: 92   ELRHAHKTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKNERSSEESNGEV 151
            E+R       E   N    +   +   G L   AE H          K +R  E+    +
Sbjct: 285  EMRENISKQTEDVKNKKENLRLREDELGQL--QAEIH----------KQQREIEKEKSNI 332

Query: 152  QTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDDRASEAEIQVEILK 211
            ++ R A+ K+  D     +      E+L                LD  A E E   E+LK
Sbjct: 333  ESERAAIIKIVEDLQHKIISLDRDAESLK---------------LDREAFENER--EVLK 375

Query: 212  ESLMQLKADKDAGEVLYNQCLETIARLESMLSQ--KDNIEAKNLKQELTRVVVQKDTVLL 269
            +   +L+ + D  E +  +      R+E M +Q  K+  +  NL +E  R    KD VL 
Sbjct: 376  QMKTELERETDEIEKIKLETQHDRQRVEEMTAQITKERDKINNLIEETNR----KDMVLN 431

Query: 270  QYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEERDSLSVLYHH 329
                  EK   +E KI   + +  ML       E E   L K  +E+ + ++ L     +
Sbjct: 432  ------EKNRDIEEKIKSIQSDKDML-------EKEKHNLEKTRSELYKVKEDLEKQKEN 478

Query: 330  CLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQLEAENLVQR 389
             L +I K   ++  + EN     ++I+ + E+++  +     L+   QNLQ E E   + 
Sbjct: 479  TLAEIQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEI 538

Query: 390  IASKDHELLEKHTEIERLQTLMHGEHSNFIQ-IESALQALQKLYSQSQKEQRNLALELKY 448
            I     EL  + +E+++ QT M    ++ I+ +++  + L K   + +++++ +  E   
Sbjct: 539  IMKDRSELDLRQSELDKQQTNM----NDIIETMKNERKLLDKDKEEMEEQKQEMEKERDN 594

Query: 449  GLLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEISKLKEIKEKLERE 508
                +K L+   +  K + Q I EE   L ++ F     L+++  EI K+KE  +   + 
Sbjct: 595  MDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKF----ELQREADEIRKIKEETQNERQS 650

Query: 509  FHTST-----EESNVLQRETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQN 563
                T     E  ++++ E  +  D+I  + E  Q   ++L+ +            +L  
Sbjct: 651  LEKMTKALIKEREDLMKIELEREADEISKIKEETQNKRQRLEKM----------TEELIR 700

Query: 564  ENFMLKETCKKEHSEKEALREKSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQF 623
            E   L    +   +EK+ L ++ K  NE  M +   E S+      L+ +R  + +++++
Sbjct: 701  EKESLAHLAEDTKTEKKIL-DEMKVANESSMADLQREKSI------LEEMRENISKLKEY 753

Query: 624  CQVLQEEKSILADEKSTLLSQLQIITESMQKILENNTVLEKS----LSDAKIEFEGLRIK 679
                +E+  +  DE   L +++Q   +   KI    T +E      + + +     L+ K
Sbjct: 754  IDNEKEKSKLREDELKKLQTEVQ---KQQSKIDMEKTNIESERAAMIREKQNMMTELKKK 810

Query: 680  SGDLEDCCKLLNDEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESA 739
            S D+E   K +  EK  L N+R +L   +E +++KL +LE+    L+      E +KE+ 
Sbjct: 811  SEDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEA- 869

Query: 740  VNQVEELFASILVQKENHSNHKHSSEARLANLENIVRVLQEEQRLGKVEFEQELDRVVNA 799
               ++++   + +Q +     K  ++     +E +   +Q+E+           D++   
Sbjct: 870  ---MKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQKER-----------DKI--- 912

Query: 800  QIEMFILQNCIEELELKNFVLLTECEKLVEASKF--SDKVISELESENLMQLIEE----- 852
                    N IEE   K+ VL  +   + E  K   SDK + E E  NL +   E     
Sbjct: 913  -------NNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVK 965

Query: 853  -------EFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESS 905
                   E  L  I+K + D+ K+   +  +      +EIK +E  +++  D+++ L++ 
Sbjct: 966  EDLEKQKENTLAEIQKEREDVEKMNENITREM-----HEIKHQEEQMNQKQDELDQLKTE 1020

Query: 906  LVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVEL 965
            +   Q   Q+L  E  +++    Q      +L  ++  +    E M+ +   L KDK E+
Sbjct: 1021 I---QNLQQELEKEKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEM 1077

Query: 966  LEENRQLRIEVVNGVEKENRS-KSTLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRN 1024
             E+ +++        EKE      +  +L  ++  ++   QVF+EE  K+   K  L R 
Sbjct: 1078 EEQKQEM--------EKEKHDFDQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELERE 1129

Query: 1025 VSDLKDAKSSAEDENSVMFHDVLALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDL 1084
              +++  K   ++E   +                   E M E+  L +   + +HL  D 
Sbjct: 1130 ADEIRKIKEETQNERQSL-------------------EKMTEE--LKKEKESFTHLAEDT 1168

Query: 1085 NQEFGVLRKNFEVKEAENVYLNESIERMDKELLEMDKRLKAAETSNAEFSRHIEELKMEQ 1144
             +E  +L K   VK A N  L   +++    L EM + + + +T + E  +  E L++ +
Sbjct: 1169 KKEQEILDK---VKVA-NESLMADLQKEKSNLEEMRENI-SKQTEDVENKK--ENLRLRE 1221

Query: 1145 EESTKIKENLDRQILEQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHR--VREEA 1202
            +E  +++  + +Q  E  +  +N +K +E   +  E+++  ++    E+EQ +  +  E 
Sbjct: 1222 DELWQLQAEIYKQQREIEKEKINIEK-LEEKQQEEESMREILQKEKEELEQLKKDINREK 1280

Query: 1203 LNLELLNKENEFKLWENEAAAFYHDLQMSSICLALLESKVSELTGVCKILDDESSAKSLE 1262
             ++E+  +  E +++E E   F  D+Q     L ++           ++L  + + + L 
Sbjct: 1281 EDIEISRELVESEIYEGEVKGF-TDVQKYKEELQIVTE---------ELLTKKRNLEQLN 1330

Query: 1263 NEHMREIISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKD 1322
            ++    + +L E +I  +K++                 LEHI+    KR  ++    +K 
Sbjct: 1331 SDVQHLMQTLEEVDIQYIKKKA---------------ELEHITSEIQKREQILEKQKKK- 1374

Query: 1323 VVIETCLRKHSHQSARENEIVLIPDGVSDLLTLQTRIRAVEKIMMEELKRRVKQKSLTTE 1382
                    + +     E E++ +     ++  LQ R   +EK   E L+R  ++  L   
Sbjct: 1375 -------LEENGWIIEEIEMMKVTLESINMEILQKR-EDMEK-EKENLRREKQETELFRV 1425

Query: 1383 STPYSSLEIATYPKVENRKKEIE-LVEENVFDRNSWRK------KPKIRLLMKDIPLDRN 1435
                 +L+  T   ++  KKEI+ ++EE    +    K        K  L  K   L++ 
Sbjct: 1426 KNERETLK-ETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQE 1484

Query: 1436 VDDQNSKYLKREHRRTNDHVLELCENNEHEPLSAPTVDHAMICHRSDDSGRYLNYSSELD 1495
             ++ N K+ + + +R ++   ++ +  E +  +   ++    C   + +G+ +   ++ +
Sbjct: 1485 REEINHKWTQFQ-QRIDEFDAQVRKQKEEDLTNQKKMEEERKC-LEEVNGKIIEMKTKAE 1542

Query: 1496 IEKELGVDKLELSKSVKEKTEDDKRR---ILERLSSDGQKLAILKMALQDLKKKTETKKK 1552
            +E      K+E  ++++E+   +K +   +  +L  + + L  +K  L  +++KTE   +
Sbjct: 1543 LEHHEINQKIEELQTLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSEL--VREKTEVDHE 1600

Query: 1553 SKQGNDIEYETVKRHIEEVEEAVMQQVSINDQMAKNVEE-----GASSLDREIPRRGSEQ 1607
             K+ ND + + +++  E++E+   + ++   +M K   E       + L++    +  E 
Sbjct: 1601 QKKLND-DIKMIEQEKEDLEKMKSEIMTQKQEMEKERSELDNKIQQTDLEKHDIEKSKEI 1659

Query: 1608 IGKLQFEVQNIQYILLKLAEENNNKVKNRISRKTGILLRRK 1648
            + KL FEV+  Q   ++L +E  +  + +I+ +  +L++ K
Sbjct: 1660 VEKLMFEVEE-QRHEIQLQKEELDIERQKIADEQDLLIQNK 1699



 Score =  197 bits (501), Expect = 2e-48
 Identities = 328/1579 (20%), Positives = 667/1579 (41%), Gaps = 271/1579 (17%)

Query: 141  ERSSEESNGEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDDRA 200
            E+  E +  E+Q  RE L KM  +      + +   E + + + +L++ +   + L    
Sbjct: 473  EKQKENTLAEIQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEIQNLQQ-- 530

Query: 201  SEAEIQVEILKESLMQL---KADKDAGEVLYNQCLETIARLESMLSQKDNIEAKNLKQEL 257
             E E + EI+ +   +L   +++ D  +   N  +ET+   E  L  KD  E +  KQE+
Sbjct: 531  -ELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKN-ERKLLDKDKEEMEEQKQEM 588

Query: 258  TRVVVQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMN 317
             +   ++D +    K   E + M++ +  + EE    L       + E + +RK   E  
Sbjct: 589  EK---ERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQ 645

Query: 318  EERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKL----EISEKHRGMLE 373
             ER SL        EK++K       ++E  + +K ++E+EA+++    E ++  R  LE
Sbjct: 646  NERQSL--------EKMTKAL-----IKEREDLMKIELEREADEISKIKEETQNKRQRLE 692

Query: 374  KSNQNLQLEAENLVQRI--ASKDHELLEKH--------TEIERLQTLMHGEHSNFIQIES 423
            K  + L  E E+L         + ++L++          +++R ++++     N  +++ 
Sbjct: 693  KMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENISKLKE 752

Query: 424  ALQ-----------ALQKLYSQSQKEQRNLALE-----------LKYGLLLLKDLELSKQ 461
             +             L+KL ++ QK+Q  + +E           ++    ++ +L+   +
Sbjct: 753  YIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMMTELKKKSE 812

Query: 462  DFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEISKLKEIKE--KLEREFHTSTEES--- 516
            D + +M+ I+ E + LH      TR ++  Q ++  L+   +  KL+RE   + +E+   
Sbjct: 813  DVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQ 872

Query: 517  -----NVLQRETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKET 571
                  +   E  +IK + QH  +R + M  Q+Q             ++    N +++ET
Sbjct: 873  MKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQ-------------KERDKINNLIEET 919

Query: 572  CKKEHSEKEALREKSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEK 631
             +K+      L EK++D+ E           +  +  + D L      +++    L + K
Sbjct: 920  NRKDM----VLNEKNRDIEE----------KIKSIQSDKDMLEKERHNLEKTRSELYKVK 965

Query: 632  SILADEKSTLLSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLN 691
              L  +K   L+++Q   E ++K+ EN T   + + + K + E +  K  +L+     + 
Sbjct: 966  EDLEKQKENTLAEIQKEREDVEKMNENIT---REMHEIKHQEEQMNQKQDELDQLKTEIQ 1022

Query: 692  DEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASIL 751
            + +  L+ E+ +++      + + S L+K+ TN+ +    ++ +++      EE+     
Sbjct: 1023 NLQQELEKEKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE--- 1079

Query: 752  VQKENHSNHKHSSEARLANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQNCIE 811
             QK+     KH  +    +L+  ++++    +L K  FE+E +++   +IE+    + I 
Sbjct: 1080 -QKQEMEKEKHDFDQSRKSLDKDLKMM----KLQKQVFEEEKNKLEQMKIELEREADEIR 1134

Query: 812  ELELKNFVLLTECEKLVEASKFSDKVISELESENLMQLIEEEFLLHRIRKFKMDIHKVCG 871
            +++ +        EK+ E  K   +  + L  +      E+E L     K K+    +  
Sbjct: 1135 KIKEETQNERQSLEKMTEELKKEKESFTHLAEDTKK---EQEIL----DKVKVANESLMA 1187

Query: 872  VLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSVLLGSLQQHQ 931
             LQ +      + +++    IS+  + +E+ + +L   ++E  QL  E        QQ +
Sbjct: 1188 DLQKEK-----SNLEEMRENISKQTEDVENKKENLRLREDELWQLQAEIYK-----QQRE 1237

Query: 932  SEGEKLKLEK-KTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKENRSKSTL 990
             E EK+ +EK +  +QE E+MRE   ILQK+K EL     QL+ ++       NR K  +
Sbjct: 1238 IEKEKINIEKLEEKQQEEESMRE---ILQKEKEEL----EQLKKDI-------NREKEDI 1283

Query: 991  AALQAEMIELRQTNQVFQEENGKMLDE---KNSLCRNVSDLKDAKSSAEDENSVMFHDVL 1047
              +  E++E    +++++ E     D    K  L     +L   K + E  NS + H + 
Sbjct: 1284 E-ISRELVE----SEIYEGEVKGFTDVQKYKEELQIVTEELLTKKRNLEQLNSDVQHLMQ 1338

Query: 1048 ALSNLNLVY------------EIFFTENMVEKRA--------LCEHLGNLSHLNNDLNQE 1087
             L  +++ Y            EI   E ++EK+         + E +  +      +N E
Sbjct: 1339 TLEEVDIQYIKKKAELEHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLESINME 1398

Query: 1088 FGVLRKNFEVKEAENVYLNESIERMDKELLEMDKRLKAAETSNAEFSRHIEELKMEQEES 1147
                R++ E KE EN+      E+ + EL  +    +  + + A   R  +E+K   EE+
Sbjct: 1399 ILQKREDME-KEKENLRR----EKQETELFRVKNERETLKETEAHLQRDKKEIKSIIEET 1453

Query: 1148 TKIKENLDRQILEQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLEL 1207
            ++ KE+L     E+    MN +K+   L    +TL+ E + + H+  Q + R +  + ++
Sbjct: 1454 SRQKEDL-----EKISTGMNVQKQ--ELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQV 1506

Query: 1208 LNKENEFKLWENEAAAFYHDLQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMR 1267
              K+ E  L   +       ++    CL  +  K+ E+    ++   E + K  E     
Sbjct: 1507 -RKQKEEDLTNQKK------MEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEE----- 1554

Query: 1268 EIISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVIET 1327
              +  L+ +I   KE+  A    +   +ED + ++                   ++V E 
Sbjct: 1555 --LQTLQEQIMKEKEKAEAMTIKLKMEREDLDQIK------------------SELVREK 1594

Query: 1328 CLRKHSHQSARENEIVLIPDGVSDLLTLQTRIRAVEKIMMEE---LKRRVKQKSLTTEST 1384
                H  Q    ++I +I     DL  +++ I   ++ M +E   L  +++Q  L     
Sbjct: 1595 TEVDHE-QKKLNDDIKMIEQEKEDLEKMKSEIMTQKQEMEKERSELDNKIQQTDLEKHDI 1653

Query: 1385 PYSSLEIATYPKVENRKKEIELVEENVFDRNSWRKKPKIRLLMKDIPLDRNVDDQNSKYL 1444
                            +K  E+VE+ +F+    R + +++    DI   +  D+Q+    
Sbjct: 1654 ----------------EKSKEIVEKLMFEVEEQRHEIQLQKEELDIERQKIADEQDLLIQ 1697

Query: 1445 -KREHRRTNDHVLELCE--NNEHEPLSAPTVDHAMICHRSDDSGRYLNYSSELDIEKELG 1501
             K E +  N+ +  + E    E E L                           ++E  L 
Sbjct: 1698 NKSELQNENERIRNINEVIKKERETLK--------------------------EMEAHLE 1731

Query: 1502 VDKLELSKSVKEKTEDDKRRILERLSSDGQKLAILKMALQDLKKKTETKKKSKQGNDIEY 1561
             +K E+ KS+ E+T   K   LE++S+D      +K   QDL K+ +  ++ K+  + E+
Sbjct: 1732 KEKEEM-KSITEETRRQKED-LEKMSTD------IKEQNQDLMKQRDLLEQEKEDINHEW 1783

Query: 1562 ETVKRHIEEVEEAVMQQVSINDQMAKNVEEGASSLDREIPRRGSEQIGKLQFEVQNIQYI 1621
              +++ I+E +  V +Q   +    K ++E   SL+ E   R  E   K + E+++I+  
Sbjct: 1784 TQLQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLE-ETKARIIEM--KTKAELEDIKKE 1840

Query: 1622 LLKLAEENNNKVKNRISRK 1640
              K  EE   +VK  +  K
Sbjct: 1841 KEKEEEEEEMRVKVEMDGK 1859



 Score =  165 bits (418), Expect = 1e-38
 Identities = 281/1382 (20%), Positives = 580/1382 (41%), Gaps = 171/1382 (12%)

Query: 346  ENAEQLKNKIEKEAEKL----EISEKHRGMLEKSNQNLQLEAENLVQRIASKDHELLEKH 401
            EN +Q    IE ++E L    E+ E  + +L++   +LQ EAE  +++I       LE  
Sbjct: 1    ENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEE-IEKIK------LETQ 53

Query: 402  TEIERLQTLMHGEHSNFIQIESALQALQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQ 461
             E +R++ +         QI+   + LQK+     +E      ++KY    +K  +    
Sbjct: 54   HERQRVEEMT-------AQIQKDREYLQKMNDNITREIH----DIKYQEKQMKQKQDELD 102

Query: 462  DFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEISK----LKEIKEKLEREFHTSTEESN 517
              K E+Q + +E +   E+       L  +Q E+ K    + +I E ++ E     ++  
Sbjct: 103  QLKTEIQNLQQELEKEKEIIMKDRSELDLKQSELDKQQTNMNDIIETMKNERKQLDKDKE 162

Query: 518  VLQRETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHS 577
             ++ +  +I+ +    ++   ++ E L+ + L    F      L+     L+    +   
Sbjct: 163  EMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRK 222

Query: 578  EKEALREKSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADE 637
             KE ++ + + + ++  E          L  E +      ++ ++  ++L E K  +A+E
Sbjct: 223  IKEEIQNERQSLEKMTEE----------LKREKESFTHLAEDTKKEQEILDEIK--VANE 270

Query: 638  KSTLLSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNL 697
              +L+++LQ    + +++ EN   + K   D K + E LR++  +L      ++ ++  +
Sbjct: 271  --SLMAELQKEKSNFEEMREN---ISKQTEDVKNKKENLRLREDELGQLQAEIHKQQREI 325

Query: 698  QNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENH 757
            + E+S + S+   + + + +L+ K+ +L+     ++ D+E+  N+ E L           
Sbjct: 326  EKEKSNIESERAAIIKIVEDLQHKIISLDRDAESLKLDREAFENEREVL----------- 374

Query: 758  SNHKHSSEARLANLENIVRVLQEEQRLGKVEFEQELDRV--VNAQI--EMFILQNCIEEL 813
               K   E     +E I           K+E + +  RV  + AQI  E   + N IEE 
Sbjct: 375  KQMKTELERETDEIEKI-----------KLETQHDRQRVEEMTAQITKERDKINNLIEET 423

Query: 814  ELKNFVLLTECEKLVEASKF--SDKVISELESENLMQLIEE------------EFLLHRI 859
              K+ VL  +   + E  K   SDK + E E  NL +   E            E  L  I
Sbjct: 424  NRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLEKQKENTLAEI 483

Query: 860  RKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVE 919
            +K + D+ K+   + I+      +EIK +E  + +  D+++ L++ +   Q   Q+L  E
Sbjct: 484  QKEREDLEKMNENITIEM-----HEIKHQEEQMKQKQDELDQLKTEI---QNLQQELEKE 535

Query: 920  NSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNG 979
              +++    +      +L  ++  +    E M+ +  +L KDK E+ E+ +++       
Sbjct: 536  KEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQKQEME------ 589

Query: 980  VEKENRSKSTLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDEN 1039
             E++N  +S + +L  ++  ++   QV +EE  K+   K  L R   +++  K   ++E 
Sbjct: 590  KERDNMDQS-IKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQNER 648

Query: 1040 SVMFHDVLALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKE 1099
              +     AL        I   E+++ K  L      +S +  +   +   L K  E   
Sbjct: 649  QSLEKMTKAL--------IKEREDLM-KIELEREADEISKIKEETQNKRQRLEKMTEELI 699

Query: 1100 AENVYLNESIERMDKELLEMDKRLKAAETSNAEFSRHIEELKMEQEESTKIKENLDRQIL 1159
             E   L    E    E   +D+   A E+S A+  R    L+  +E  +K+KE +D +  
Sbjct: 700  REKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENISKLKEYIDNE-K 758

Query: 1160 EQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLELLNKENE-----F 1214
            E+S+   +  K+++   +  ++     KT +       +RE+   +  L K++E      
Sbjct: 759  EKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEIQM 818

Query: 1215 KLWENEAAAFYHDLQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMREI---IS 1271
            K    E    ++D ++ +  +  L+ K+ +L    K L  +  A   E E M+++   + 
Sbjct: 819  KEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDLQ 878

Query: 1272 LLESEIGGLK-------EQLSAYVPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVV 1324
            +   EI  +K       +++      +   ++  N+L    +  T R  +V N   +D+ 
Sbjct: 879  IQADEIEKIKLETQHDRQRVEEMAAQIQKERDKINNL----IEETNRKDMVLNEKNRDIE 934

Query: 1325 IETCLRKHSHQSARENEIVLIPDGVSDLLTLQTRIRAVEKIMMEELKRRVKQKSLTTEST 1384
             E      S +   E E   +    S+L  ++  +   ++  + E+++  +      E+ 
Sbjct: 935  -EKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKMNENI 993

Query: 1385 PYSSLEIATYPKVENRKK-EIELVEENVFDRNSWRKKPKIRLLMKDIPLDRNVDDQNSKY 1443
                 EI    +  N+K+ E++ ++  + +     +K K  ++MK    DR+  D     
Sbjct: 994  TREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEK-EIIMK----DRSQFDLRQSE 1048

Query: 1444 LKREHRRTNDHVLELCEN------NEHEPLSAPTVDHAMICHRSDDSGRYLNYSSE-LDI 1496
            L ++    ND ++E  +N       + E +     +     H  D S + L+   + + +
Sbjct: 1049 LDKQQTNMND-IMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDKDLKMMKL 1107

Query: 1497 EKEL---GVDKLELSKSVKEKTEDDKRRILERLSSDGQKLAILKMAL-----------QD 1542
            +K++     +KLE  K   E+  D+ R+I E   ++ Q L  +   L           +D
Sbjct: 1108 QKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESFTHLAED 1167

Query: 1543 LKKKTETKKKSKQGND---IEYETVKRHIEEVEEAVMQQVSINDQMAKNV---EEGASSL 1596
             KK+ E   K K  N+    + +  K ++EE+ E + +Q    +   +N+   E+    L
Sbjct: 1168 TKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLREDELWQL 1227

Query: 1597 DREIPRR---------GSEQIGKLQFEVQNIQYILLKLAEENNNKVKNRISRKTGILLRR 1647
              EI ++           E++ + Q E ++++ IL K  EE     K+    K  I + R
Sbjct: 1228 QAEIYKQQREIEKEKINIEKLEEKQQEEESMREILQKEKEELEQLKKDINREKEDIEISR 1287

Query: 1648 KL 1649
            +L
Sbjct: 1288 EL 1289



 Score =  149 bits (377), Expect = 5e-34
 Identities = 276/1438 (19%), Positives = 592/1438 (40%), Gaps = 162/1438 (11%)

Query: 24   KNSKWLLENLTDIDTKVKS-MIKL-IEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRA 81
            +N +  LE +T    K +  ++K+ +E EAD  ++  E    KR  L K+ EE  R   +
Sbjct: 645  QNERQSLEKMTKALIKEREDLMKIELEREADEISKIKEETQNKRQRLEKMTEELIREKES 704

Query: 82   LAERYDHAMGELRHAHKTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKNE 141
            LA   +    E +   + M  A  +S   +  + S    +  +           + K   
Sbjct: 705  LAHLAEDTKTEKKILDE-MKVANESSMADLQREKSILEEMRENISKLKEYIDNEKEKSKL 763

Query: 142  RSSE--ESNGEVQTLREAL----AKMQSDKDALFLQYQESLENLSKMETDLN-------- 187
            R  E  +   EVQ  +  +      ++S++ A+  + Q  +  L K   D+         
Sbjct: 764  REDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEIQMKEILT 823

Query: 188  --KAQNNARGLDDRASEAEIQVEI-LKESLMQLKADKDAGEVLYNQCLETIARLESMLS- 243
              +  +N R L  R  E   Q  I L+    +LK D++A E   N+  E + ++++ L  
Sbjct: 824  EKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFE---NE-KEAMKQMKTDLQI 879

Query: 244  QKDNIEAKNLKQELTRVVVQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTE 303
            Q D IE   L+ +  R  V++    +Q ++       + N I        +LN++    E
Sbjct: 880  QADEIEKIKLETQHDRQRVEEMAAQIQKER-----DKINNLIEETNRKDMVLNEKNRDIE 934

Query: 304  LEVETLRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLE 363
             ++++++ +   + +ER +L            K  +E+  V+E+ E+     +KE    E
Sbjct: 935  EKIKSIQSDKDMLEKERHNLE-----------KTRSELYKVKEDLEK-----QKENTLAE 978

Query: 364  ISEKHRGMLEKSNQNLQLEAENLV---QRIASKDHELLEKHTEIERLQTLMHGEHSNFIQ 420
            I +K R  +EK N+N+  E   +    +++  K  EL +  TEI+ LQ  +  E    ++
Sbjct: 979  I-QKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMK 1037

Query: 421  IESALQALQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHEL 480
              S     Q   S+  K+Q N+   ++      K L+  K++ +E+ Q + +E     + 
Sbjct: 1038 DRSQFDLRQ---SELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQS 1094

Query: 481  NFSSTRSLKKQQMEISKLKEIKEKLER---EFHTSTEESNVLQRETHQIKDDIQHLNERY 537
              S  + LK  +++    +E K KLE+   E     +E   ++ ET   +  ++ + E  
Sbjct: 1095 RKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEEL 1154

Query: 538  QAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALRE---------KSKD 588
            +   E    L  +       +  ++  N  L    +KE S  E +RE         ++K 
Sbjct: 1155 KKEKESFTHLAEDTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKK 1214

Query: 589  MNEVLMENAC--MEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQ 646
             N  L E+    ++  +     E++  +  ++++++  Q  +  + IL  EK  L    +
Sbjct: 1215 ENLRLREDELWQLQAEIYKQQREIEKEKINIEKLEEKQQEEESMREILQKEKEELEQLKK 1274

Query: 647  IITESMQKILENNTVLEKSLSDAKIE-FEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLI 705
             I    + I  +  ++E  + + +++ F  ++    +L+   + L  +K NL+   S + 
Sbjct: 1275 DINREKEDIEISRELVESEIYEGEVKGFTDVQKYKEELQIVTEELLTKKRNLEQLNSDVQ 1334

Query: 706  SQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHSNHKHSSE 765
              ++ +EE      KK   LE   ++++K ++    Q ++L  +  + +E          
Sbjct: 1335 HLMQTLEEVDIQYIKKKAELEHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLES 1394

Query: 766  ARLANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQNCIE--ELELKNFVLLTE 823
              +  L+    + +E++ L + + E EL RV N +  +   +  ++  + E+K+ +  T 
Sbjct: 1395 INMEILQKREDMEKEKENLRREKQETELFRVKNERETLKETEAHLQRDKKEIKSIIEETS 1454

Query: 824  CEKLVEASKFSDKV-ISELESENLMQLIEEEF--LLHRIRKFKMDIHKVCGVL--QIDSD 878
             +K  +  K S  + + + E +N    +E+E   + H+  +F+  I +    +  Q + D
Sbjct: 1455 RQK-EDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEED 1513

Query: 879  GGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLK 938
                 ++++E   +  +  KI  +++       E  Q + E   L   + + + + E + 
Sbjct: 1514 LTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAMT 1573

Query: 939  LEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKENRSKSTLAALQAEMI 998
            ++ K   ++ + ++ +   L ++K E+  E ++L  ++   +E+E   K  L  +++E++
Sbjct: 1574 IKLKMEREDLDQIKSE---LVREKTEVDHEQKKLNDDI-KMIEQE---KEDLEKMKSEIM 1626

Query: 999  ELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVLALSNLNLVYEI 1058
              +Q      E+    LD  N + +   +  D + S E    +MF        + L  E 
Sbjct: 1627 TQKQE----MEKERSELD--NKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRHEIQLQKE- 1679

Query: 1059 FFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIERMDKELLE 1118
               E  +E++ + +    L    ++L  E   +R            +NE I++  + L E
Sbjct: 1680 ---ELDIERQKIADEQDLLIQNKSELQNENERIRN-----------INEVIKKERETLKE 1725

Query: 1119 MDKRLKAAETSNAEFSRHIEELKMEQEESTKIKENLDRQILEQSENCMNHKKEIEHLNEA 1178
            M+  L+  +          EE+K   EE+ + KE+L++   +  E   +  K+ + L + 
Sbjct: 1726 MEAHLEKEK----------EEMKSITEETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQE 1775

Query: 1179 NETLQFEMKTLLHEVEQHRVREEALNLELLNKENEFKLWENEAAAFYHDLQMSSICLALL 1238
             E +  E   L   +++   +      E L K+ E K                   L   
Sbjct: 1776 KEDINHEWTQLQQRIDEFDAQVSKQKEEDLTKQKEMKEERKS--------------LEET 1821

Query: 1239 ESKVSELTGVCKILD-DESSAKSLENEHMREIISLLESEIGGLKEQLSAYVPLVSSLKED 1297
            ++++ E+    ++ D  +   K  E E MR  + +   E+  +K          S LK +
Sbjct: 1822 KARIIEMKTKAELEDIKKEKEKEEEEEEMRVKVEMDGKELDRIK----------SELKRE 1871

Query: 1298 FNSLEHISLLWTKRNSVVGNGAQKDVVIETCLRKHSHQSARENEIVLIPDGVSDLLTLQT 1357
             + ++H          ++    Q    +++ + K   Q   E               L+ 
Sbjct: 1872 RSEIDHEQKKLNDDKKIIEQEKQNLEKMKSEIMKQRQQMEEERS------------ELEN 1919

Query: 1358 RIRA--VEKIMMEELKRRVKQKSLTTESTPYSSLEIATYPKVENRKKEIELVEENVFD 1413
            +I+   +EK  +E  K  V++  +  E   +         +++ +K+E+++  + + D
Sbjct: 1920 KIKQTYIEKCDIENSKEIVQKLMVEVEEQKH---------EIQFQKEELDIERQKIAD 1968



 Score =  114 bits (285), Expect = 3e-23
 Identities = 186/941 (19%), Positives = 382/941 (39%), Gaps = 123/941 (13%)

Query: 40   VKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHAMGELRHAHKT 99
            ++ M + +++E +SF   AE   KK  E++  V+    +  A  ++    + E+R     
Sbjct: 1147 LEKMTEELKKEKESFTHLAEDT-KKEQEILDKVKVANESLMADLQKEKSNLEEMRENISK 1205

Query: 100  MPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKNERSSEESNGEVQTLREALA 159
              E   N    +   +     L   AE +   R   + K N    EE   E +++RE L 
Sbjct: 1206 QTEDVENKKENLRLREDELWQL--QAEIYKQQREIEKEKINIEKLEEKQQEEESMREILQ 1263

Query: 160  KMQSDKDALFLQYQESLENL--SKMETDLNKAQNNARGLDDRASEAEIQVEILKESLMQL 217
            K + + + L        E++  S+   +    +   +G  D     E +++I+ E L+  
Sbjct: 1264 KEKEELEQLKKDINREKEDIEISRELVESEIYEGEVKGFTDVQKYKE-ELQIVTEELLTK 1322

Query: 218  KADKDAGEVLYNQCLETIARLESMLSQKDNIEAKNLKQELTRVVVQKDTVLLQYKQCLEK 277
            K + +         ++T+  ++    +K     K   + +T  + +++ +L + K+ LE+
Sbjct: 1323 KRNLEQLNSDVQHLMQTLEEVDIQYIKK-----KAELEHITSEIQKREQILEKQKKKLEE 1377

Query: 278  IPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEERDSLSVLYHHCLEKISKM 337
               +  +I + +     +N +I +   ++E  ++NL    +E +    L+    E+ +  
Sbjct: 1378 NGWIIEEIEMMKVTLESINMEILQKREDMEKEKENLRREKQETE----LFRVKNERETLK 1433

Query: 338  ENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQLEAENLVQRIASKDHEL 397
            E E  H+Q + +++K+ IE+ + + E  EK    +    Q L+ + + L Q     +H+ 
Sbjct: 1434 ETEA-HLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKW 1492

Query: 398  LEKHTEIERLQTLMHGEHSNFIQIESALQALQKLYSQSQKEQRNLALELKYGLLLLKDLE 457
             +    I+     +  +              + L +Q + E+    LE   G ++  +++
Sbjct: 1493 TQFQQRIDEFDAQVRKQKE------------EDLTNQKKMEEERKCLEEVNGKII--EMK 1538

Query: 458  LSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEISKLKEIKEKLEREFHTSTEESN 517
               +    E+   +EE +TL E      +  +K +    KLK  +E L++       E  
Sbjct: 1539 TKAELEHHEINQKIEELQTLQE---QIMKEKEKAEAMTIKLKMEREDLDQIKSELVREKT 1595

Query: 518  VLQRETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHS 577
             +  E  ++ DDI+ + E+ +  LE+++S            ++++ E   L    ++   
Sbjct: 1596 EVDHEQKKLNDDIKMI-EQEKEDLEKMKS------EIMTQKQEMEKERSELDNKIQQTDL 1648

Query: 578  EKEALREKSKDMNEVLM---ENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSIL 634
            EK  + EKSK++ E LM   E    E  L    +ELD  R  + + Q    +L + KS L
Sbjct: 1649 EKHDI-EKSKEIVEKLMFEVEEQRHEIQLQ--KEELDIERQKIADEQD---LLIQNKSEL 1702

Query: 635  ADEKSTLLSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEK 694
             +E   + +  ++I +  + + E    LEK   + K   E  R +  DLE     + ++ 
Sbjct: 1703 QNENERIRNINEVIKKERETLKEMEAHLEKEKEEMKSITEETRRQKEDLEKMSTDIKEQN 1762

Query: 695  NNLQNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASILVQK 754
             +L  +R +L  + E +  + + L++++   +   A V K KE  + +          QK
Sbjct: 1763 QDLMKQRDLLEQEKEDINHEWTQLQQRIDEFD---AQVSKQKEEDLTK----------QK 1809

Query: 755  ENHSNHKHSSEARLANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQNCIEELE 814
            E     K   E +   +E   +   E+ +  K + E+E +  V  +++            
Sbjct: 1810 EMKEERKSLEETKARIIEMKTKAELEDIKKEKEKEEEEEEMRVKVEMD------------ 1857

Query: 815  LKNFVLLTECEKLVEASKFSDKVISELESENLMQLIEEEFLLHRIRKFKMDIHKVCGVLQ 874
                             K  D++ SEL+ E                             +
Sbjct: 1858 ----------------GKELDRIKSELKRERS---------------------------E 1874

Query: 875  IDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSVLLGSLQQHQSEG 934
            ID +    N+ KK    I +    +E ++S ++K   + QQ+  E S L   ++Q   E 
Sbjct: 1875 IDHEQKKLNDDKKI---IEQEKQNLEKMKSEIMK---QRQQMEEERSELENKIKQTYIEK 1928

Query: 935  EKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIE 975
              ++  K+ V++    + EQ   +Q  K EL  E +++  E
Sbjct: 1929 CDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADE 1969



 Score = 80.1 bits (196), Expect = 5e-13
 Identities = 98/528 (18%), Positives = 242/528 (45%), Gaps = 50/528 (9%)

Query: 134  THRSKKN-ERSSEESNGEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQ-- 190
            T R K++ E+ S   N + Q L+     ++ +++ +  ++ +  + + + +  + K +  
Sbjct: 1453 TSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEE 1512

Query: 191  ---NNARGLDDRASEAEIQVEILKESLMQLKADKDAGEVLYNQCLETIARL-ESMLSQKD 246
               N  +  ++R    E+  +I++   M+ KA+ +  E+  NQ +E +  L E ++ +K+
Sbjct: 1513 DLTNQKKMEEERKCLEEVNGKIIE---MKTKAELEHHEI--NQKIEELQTLQEQIMKEKE 1567

Query: 247  NIEAKNLKQELTR---------VVVQKDTVLLQYKQCLEKIPMLEN-------------- 283
              EA  +K ++ R         +V +K  V  + K+  + I M+E               
Sbjct: 1568 KAEAMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMT 1627

Query: 284  -KIALAEENSRMLNDQIERTELEVETLRKN-------LAEMNEERDSLSVLYHHCLEKIS 335
             K  + +E S  L+++I++T+LE   + K+       + E+ E+R  + +       +  
Sbjct: 1628 QKQEMEKERSE-LDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRHEIQLQKEELDIERQ 1686

Query: 336  KMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQLEAENLVQRIASKDH 395
            K+ +E   + +N  +L+N+ E+     E+ +K R  L++   +L+ E E +     S   
Sbjct: 1687 KIADEQDLLIQNKSELQNENERIRNINEVIKKERETLKEMEAHLEKEKEEM----KSITE 1742

Query: 396  ELLEKHTEIERLQTLMHGEHSNFIQIESALQALQKLYSQSQKEQRNLALELKYGLLLLKD 455
            E   +  ++E++ T +  ++ + ++    L+  ++  +    + +    E    +   K+
Sbjct: 1743 ETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQVSKQKE 1802

Query: 456  LELSKQ-DFKEEMQGIVEENKTLHELNFSST-RSLKKQQMEISKLKEIKEKLEREFHTST 513
             +L+KQ + KEE + + E    + E+   +    +KK++ +  + +E++ K+E +     
Sbjct: 1803 EDLTKQKEMKEERKSLEETKARIIEMKTKAELEDIKKEKEKEEEEEEMRVKVEMDGKELD 1862

Query: 514  EESNVLQRETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCK 573
               + L+RE  +I  + + LN+  + + ++ Q+L    +      + ++ E   L+   K
Sbjct: 1863 RIKSELKRERSEIDHEQKKLNDDKKIIEQEKQNLEKMKSEIMKQRQQMEEERSELENKIK 1922

Query: 574  KEHSEKEALREKSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQ 621
            + + EK  +    + + ++++E    +  +    +ELD  R  + + Q
Sbjct: 1923 QTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQ 1970


>UniRef100_UPI0000437337 UPI0000437337 UniRef100 entry
          Length = 1701

 Score =  197 bits (502), Expect = 2e-48
 Identities = 325/1624 (20%), Positives = 677/1624 (41%), Gaps = 198/1624 (12%)

Query: 39   KVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHAMGELRHAHK 98
            K++ M   +E EAD   +  E    +R  L K+ EE  +      E + H   + +   +
Sbjct: 210  KLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKE----KESFTHLAEDTKKEQE 265

Query: 99   TMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKNERSSEESNGEVQTLREAL 158
             + +    +   + +      +L    E+ +       +KK      E   E+  L+  +
Sbjct: 266  ILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLRED--ELWQLQAEI 323

Query: 159  AKMQSD--KDALFLQYQES--LENLSKMETDLNKAQNNARGLDDRASEAEIQVEILKESL 214
             K Q +  K+ + ++ + +  ++N+  ++  +     ++  L       E + E+LK+  
Sbjct: 324  YKQQREIEKEKINIESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMK 383

Query: 215  MQLKADKDAGEVLYNQCLETIARLESMLSQ--KDNIEAKNLKQELTRVVVQKDTVLLQYK 272
             +L+ + D  E +  +      R+E M +Q  KD  +  NL +E  R    KD VL +  
Sbjct: 384  TELEREADEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNR----KDMVLNEKN 439

Query: 273  QCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEERDSLSVLYHHCLE 332
            + +EK      KI   + +  ML       E E   L K  +E+ + ++ L     + L 
Sbjct: 440  RDIEK------KIKSIQSDKDML-------EKEKHDLEKTRSELYKVKEDLEKQKENTLA 486

Query: 333  KISKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQLEAENLVQRIAS 392
            +I K   ++  + EN  +  ++I+ + E++   +     L+   QNLQ E E   + I  
Sbjct: 487  QIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMK 546

Query: 393  KDHELLEKHTEIERLQT----LMHGEHSNFIQIESALQALQKLYSQSQKEQRNLALELKY 448
               +L  + +E+++ QT    +M    +   Q++   + +++   + +KE+ N+    K 
Sbjct: 547  ARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKS 606

Query: 449  GLLLLKDLELSKQDFKEE--------------MQGIVEENKTLHEL--NFSS-TRSLKKQ 491
                LK ++L KQ  +EE              M  + +E   L E+  N S  T  ++K+
Sbjct: 607  LDEDLKMMKLQKQVIEEEKNNLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKE 666

Query: 492  QMEISKLKEIKEKLEREFH-----TSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQS 546
            + +I   ++  E+L+ E H     T  E+SN+ +RE   I  D++ L  +  ++    +S
Sbjct: 667  KDKIRLREDELEQLQAEIHKQQSETEIEKSNI-ERERAAIIKDVEDLQSKIISLDRDAES 725

Query: 547  LGLNPNSFAASVRDLQNENFMLK---ETCKKEHSEKEALREKSKDMNEVLMENACMEFSL 603
            L L+  +F     +L+     L+   +  +K   E +  R++ ++M    ME    E   
Sbjct: 726  LKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQ 785

Query: 604  LGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESMQKILENNTVLE 663
            L  N  +  +    +E+++    + + +  L ++   + +Q Q++ E   K+ +    LE
Sbjct: 786  LDKNKVM--IEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIGLE 843

Query: 664  KSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVEEKLSNLEK-KV 722
            +   +     E  + +  +LE     L +E+  L  E          ++ K   L+K KV
Sbjct: 844  READEISKIKEETQNERQNLEKMANALKEEREYLAEE----------IKRKNQVLDKIKV 893

Query: 723  TNLEEKYADVEKDKESAVNQVEELFASILVQKENHSNHKHSSEAR---LANLENIVRVLQ 779
             N E   AD++K+K      +EE+  +I  Q E+  N K  S+ R   L  L+  V+  Q
Sbjct: 894  AN-ESTLADLQKEKRI----LEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQ 948

Query: 780  EEQRLGKVEFEQELDRVVNAQIEMFI-LQNCIEELELKNFVLLTECEKLVEASKFSDKVI 838
             E  + K   E E   ++  +  M   L+   E++E++   +LTE E L        K +
Sbjct: 949  SEIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDV 1008

Query: 839  SELESENLMQLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGG---DNEIKKEEIPISRI 895
             +L+ + LM+L   E     +++ + ++      L ++ D      D++  +      + 
Sbjct: 1009 EDLQ-QKLMKLFRGE-----LQRQRDEVESSRQALIMEKDQFKLKIDHQRNEMSAAFEKE 1062

Query: 896  LDKIESLESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQN 955
              ++E++E+ L   + +  + L + + +   LQQ ++E   L  EK+ VE+  + ++ + 
Sbjct: 1063 HKRLENMENDLENQRAKLAESLNDAAKMEQKLQQMKNE---LNKEKEQVEEMKQMVKTER 1119

Query: 956  VILQKDKVELLEENRQLRIEVVNGVEKENRSKSTL------AALQAEMIELRQTNQVFQE 1009
            V ++++K    EE R+   E+ +G EK  +           A +  E  E R+  +  Q 
Sbjct: 1120 VKIEQEK----EEMRKQTQEIEDGHEKLQKKTEIADKLLQDANMTTEQNEYRKLIEELQR 1175

Query: 1010 ENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVLALSNLNLVYEIFFTENMVEKRA 1069
            E  ++   KN + +   DL++ KS+ E +   + H+   + +              EK A
Sbjct: 1176 EKEQLEISKNQIEQEKKDLQNMKSNLERQLESLRHEKANVED--------------EKNA 1221

Query: 1070 LCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIERMDKELLEMDKRLKAAETS 1129
            L +       + N + +E   L   +   E E   + E   R++    E+ K     + S
Sbjct: 1222 LEKMRSESKEIQNAIRKEREDLENCWVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKS 1281

Query: 1130 NAEFSRHIEELKMEQEESTKIKENLDRQILEQSENCMNHKKEIEHLNEANETLQFEMKTL 1189
                    E++  + EE  ++K  + R            K+EIE  ++  +    +++  
Sbjct: 1282 RENIESREEKINNKMEELLQMKVEMGRT-----------KEEIEKESQRLQDATIDLENA 1330

Query: 1190 LHEVEQHRVR-EEALNLELLNKENEFKLW-ENEAAAFYHDLQMSSICLALLESKVSELTG 1247
              E+++   + E+ +++++  KE E K+  + E      ++++    +  LE +++++  
Sbjct: 1331 KAEIQRQEDKFEDIIDIKIQEKEREIKIQLDKETKRLSEEIELK---VKDLEMEMADMKR 1387

Query: 1248 VCKILDDESSAKSLENEHMREIISLLESEIGGLKEQLSAYVPLVSSLKEDFN-----SLE 1302
              + ++D       E + +++    LE ++  L ++    +  + +  E          E
Sbjct: 1388 QKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTQETKIKIIEMKTKTEPEKIKKEKEKE 1447

Query: 1303 HISLLWTKRNSVVGNGAQKDVVIETCLRKHSHQSARENEIV-LIPDGVSDLLTLQTRIRA 1361
               ++  K         Q    +E    +  H+  + N+   +I     DL  +++ I  
Sbjct: 1448 EEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMK 1507

Query: 1362 VEKIMMEE---LKRRVKQKSLTTESTPYSSLEIATYPKVENRKKEIELVEENVFDRNSWR 1418
              + M EE   L  ++KQ  L                 +EN K   E+V++ + +    R
Sbjct: 1508 QRQQMEEERSELDNKIKQTDLERHD-------------IENSK---EIVQKLMVEVEEQR 1551

Query: 1419 KKPKIRLLMKDIPLDRNVDDQ-----NSKYLKREHRRTNDHVLELCENNEHEPLSAPTVD 1473
            K  +++    DI   +  D+Q     N   L+ E+ R  +   E+    E E L      
Sbjct: 1552 KDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEI--KKEKETLK----- 1604

Query: 1474 HAMICHRSDDSGRYLNYSSELDIEKELGVDKLELSKSVKEKTEDDKRRILERLSSDGQKL 1533
                                 ++E  L  +K E+ +SV E+T+  ++  LE++S+D  K 
Sbjct: 1605 ---------------------EMEAHLRKEKEEM-RSVIEETQRRQKEDLEKMSTDVNKQ 1642

Query: 1534 AILKMALQDLKKKTETKKKSKQGNDIEYETVKRHIEEVEEAVMQQVSINDQMAKNVEEGA 1593
                   QDL  + +  K+ ++  + ++  +++ I+E +  V +Q   +    K +EE  
Sbjct: 1643 N------QDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEER 1696

Query: 1594 SSLD 1597
             SL+
Sbjct: 1697 KSLE 1700



 Score =  175 bits (444), Expect = 9e-42
 Identities = 329/1694 (19%), Positives = 708/1694 (41%), Gaps = 259/1694 (15%)

Query: 132  RPTHRSKKNERSSEESNGEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQN 191
            R  H  K  E    +   E+  L+  +  +Q + +       +    L   +++L+K Q 
Sbjct: 36   REMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQT 95

Query: 192  NARGLDDRASEAEIQVEILKESLMQLKADKDAGEVLYNQCLETI------ARLESMLSQK 245
            N   + +       Q++  KE + + K + +      +Q  +++       +L+  + ++
Sbjct: 96   NMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEE 155

Query: 246  DNIEAKNLKQELTRVV-----VQKDTVLLQYKQCLEK-IPMLENKIALAEENSRMLN--- 296
            +  + + +K EL R       ++++T   + ++ L+K + M++ +  + EE    L    
Sbjct: 156  EKNKLEQMKIELEREADEISKIKEETQNKRQRKSLDKDLKMMKLQKQVFEEEKNKLEQMK 215

Query: 297  -------DQIERTELEVETLRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHV----- 344
                   D+I + + E +  R++L +M EE       + H  E  +K E EIL       
Sbjct: 216  IELEREADEIRKIKEETQNERQSLEKMTEELKKEKESFTHLAED-TKKEQEILDKVKVAN 274

Query: 345  ----------QENAEQLKNKIEKEAEKLEISE------------------KHRGMLEKSN 376
                      + N E+++  I K+ E +E  +                  K +  +EK  
Sbjct: 275  ESLMADLQKEKSNLEEMRENISKQTEDVENKKENLRLREDELWQLQAEIYKQQREIEKEK 334

Query: 377  QNLQLEAENLVQRIASKDHELLEKHTEIERLQT---LMHGEHSNFIQIESAL-------- 425
             N++ E   +++ +    H+++    + E L+        E     Q+++ L        
Sbjct: 335  INIESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELEREADEIE 394

Query: 426  ----------QALQKLYSQSQKEQ---RNLALELKYGLLLL----KDLEL------SKQD 462
                      Q ++++ +Q QK++    NL  E     ++L    +D+E       S +D
Sbjct: 395  KIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIKSIQSDKD 454

Query: 463  FKEEMQGIVEEN-----KTLHELNFSSTRSLKKQQMEISKLKEIKEKLEREFHT---STE 514
              E+ +  +E+      K   +L      +L + Q E   L+++ E + RE H      E
Sbjct: 455  MLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEE 514

Query: 515  ESNVLQRETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKK 574
            + N  Q E  Q+K +IQ+L +  +   E +       +   + +   Q     + ET K 
Sbjct: 515  QMNQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKN 574

Query: 575  EHSE----KEALREKSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEE 630
            E  +    KE + E+ ++M +   E   M+ S   L+++L  ++     +Q+  QV++EE
Sbjct: 575  ERKQLDKDKEEMEEQKQEMEK---ERDNMDQSRKSLDEDLKMMK-----LQK--QVIEEE 624

Query: 631  KSILADEKSTLLSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLL 690
            K+ L + K    S +  + +    + E    + K   D + E + +R++  +LE     +
Sbjct: 625  KNNLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKEKDKIRLREDELEQLQAEI 684

Query: 691  ND-------EKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLE---EKYADVEKDKESAV 740
            +        EK+N++ ER+ +I  +E ++ K+ +L++   +L+   E + + +++ +   
Sbjct: 685  HKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMK 744

Query: 741  NQVEELFASILVQKENHSNHKHSSEARLANLENIVRVLQEEQRLGKVEFEQELDRVVNAQ 800
             ++E     I   K    + +   E   A+    +   +++    KV  E++   +   +
Sbjct: 745  TELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKR 804

Query: 801  IEMFILQNCIEE----LELKNFVLLTECEKLVEASKFSDKVISELESENLMQLIEEEFLL 856
             +M   +  ++E    ++ +  VL  E  KL +      K+  E E++ + ++ EE    
Sbjct: 805  DDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQM-----KIGLEREADEISKIKEE---- 855

Query: 857  HRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIE-SLESSLVKSQEENQQ 915
               +  + ++ K+   L+ + +   + EIK++    +++LDKI+ + ES+L   Q+E + 
Sbjct: 856  --TQNERQNLEKMANALKEEREYLAE-EIKRK----NQVLDKIKVANESTLADLQKEKRI 908

Query: 916  LLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIE 975
            L      +   ++  ++E EK KL     E E + ++ +   +QK + E+  E   +  E
Sbjct: 909  LEEMRENISKQIEDIENEKEKSKLR----EDELKKLQTE---VQKQQSEIDMEKTNIESE 961

Query: 976  VVNGVEKENRSKSTLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKD----- 1030
                + +E ++  T    ++E +E++    + ++E   + +++N L ++V DL+      
Sbjct: 962  RA-AMIREKQNMMTELKKKSEDVEMQMKEILTEKE--LLHNDRNLLKKDVEDLQQKLMKL 1018

Query: 1031 -----AKSSAEDENS----VMFHDVLAL------SNLNLVYE-----IFFTENMVE--KR 1068
                  +   E E+S    +M  D   L      + ++  +E     +   EN +E  + 
Sbjct: 1019 FRGELQRQRDEVESSRQALIMEKDQFKLKIDHQRNEMSAAFEKEHKRLENMENDLENQRA 1078

Query: 1069 ALCEHLGN-------LSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIERMDKELLEM-- 1119
             L E L +       L  + N+LN+E   + +  ++ + E V + +  E M K+  E+  
Sbjct: 1079 KLAESLNDAAKMEQKLQQMKNELNKEKEQVEEMKQMVKTERVKIEQEKEEMRKQTQEIED 1138

Query: 1120 ------------DKRLKAAE--TSNAEFSRHIEELKMEQ----------EESTKIKENLD 1155
                        DK L+ A   T   E+ + IEEL+ E+          E+  K  +N+ 
Sbjct: 1139 GHEKLQKKTEIADKLLQDANMTTEQNEYRKLIEELQREKEQLEISKNQIEQEKKDLQNMK 1198

Query: 1156 RQILEQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLE--LLNKENE 1213
              +  Q E+  + K  +E    A E ++ E K +     Q+ +R+E  +LE   +  E E
Sbjct: 1199 SNLERQLESLRHEKANVEDEKNALEKMRSESKEI-----QNAIRKEREDLENCWVEIEGE 1253

Query: 1214 FKLWENEAAAFYHDLQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMREIISLL 1273
             K  E E       L+M    +  ++S++       K  ++  S +   N  M E++  +
Sbjct: 1254 KKRMEEET----RRLEMHREEIKKVDSELQ------KSRENIESREEKINNKMEELLQ-M 1302

Query: 1274 ESEIGGLKEQLSAYVPLVSSLKEDF-NSLEHISLLWTKRNSVVGNGAQ-KDVVIETCLRK 1331
            + E+G  KE++      +     D  N+   I     K   ++    Q K+  I+  L K
Sbjct: 1303 KVEMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQLDK 1362

Query: 1332 HSHQSARENEIVLIPDGVSDLLTLQTRIRAVE--KIMMEELKRRVKQKSL--------TT 1381
             + + + E E+  + D   ++  ++ + + +E  K ++E+ K+ +KQ+           T
Sbjct: 1363 ETKRLSEEIEL-KVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLT 1421

Query: 1382 ESTPYSSLEIATYPKVENRKKEIELVEENVFDRNSWRKKPKIRLLMKDIPLDRNVDDQNS 1441
            + T    +E+ T  + E  KKE E  EE V       KK ++  +   +   R+  D   
Sbjct: 1422 QETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQ 1481

Query: 1442 KYLKREHRRTNDHVLELCENNEHEPLSAPTVDHAMICHRSDDSGRYLNYSSELDIEKELG 1501
            K L  + +          E  + E + +  +         ++     N   + D+E+   
Sbjct: 1482 KKLNDDKKMIEQ------EKEDLEKMKSEIMKQRQ--QMEEERSELDNKIKQTDLERHDI 1533

Query: 1502 VDKLELSKSVKEKTEDDKRRI---LERLSSDGQKLAILKMALQDLKKKTETKKKSKQGND 1558
             +  E+ + +  + E+ ++ I    E L  + QK+A  +  +   K K + + +  +  D
Sbjct: 1534 ENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMD 1593

Query: 1559 IEYETVKRHIEEVEEAVMQQVSINDQMAKNVEEGASSLDREIPRRGSEQIGKLQFEVQNI 1618
             E +  K  ++E+E  + ++    ++M   +EE      +E   + S  + K   ++ N 
Sbjct: 1594 EEIKKEKETLKEMEAHLRKE---KEEMRSVIEE-TQRRQKEDLEKMSTDVNKQNQDLMNQ 1649

Query: 1619 QYILLKLAEENNNK 1632
            + +L +  EE N+K
Sbjct: 1650 RDLLKQEREEINHK 1663



 Score =  161 bits (407), Expect = 2e-37
 Identities = 255/1294 (19%), Positives = 536/1294 (40%), Gaps = 203/1294 (15%)

Query: 29   LLENLTDIDTKVKSMIK----LIEEEADSFARRAEMYY------KKRPELMKLVEEFYRA 78
            L E   DI+ K+KS+      L +E+ D    R+E+Y       K++   +  +++    
Sbjct: 435  LNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQKERED 494

Query: 79   YRALAERYDHAMGELRHAHKTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSK 138
               + E     M E++H  + M +             +    L  + E    AR     +
Sbjct: 495  LEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRR 554

Query: 139  KNERSSEESNGEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDD 198
            ++E   +++N     + + +  M++++  L    +E  E   +ME + +    + + LD+
Sbjct: 555  QSELDKQQTN-----MNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDE 609

Query: 199  RASEAEIQVEILKESLMQLKADKDAGEVLYNQCLETIARLESMLS-----------QKDN 247
                 ++Q ++++E    L   K A E       +  + LE M             +KD 
Sbjct: 610  DLKMMKLQKQVIEEEKNNLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIEKEKDK 669

Query: 248  I-----EAKNLKQEL----TRVVVQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQ 298
            I     E + L+ E+    +   ++K  +  +    ++ +  L++KI   + ++  L   
Sbjct: 670  IRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLD 729

Query: 299  IERTELEVETLRKNLAEMNEERDSLSVLY---HHCLEKISKMENEILHVQENAEQL--KN 353
             E  E E E L++   E+  E D +  +     H  +++ +M  + +    N  +   KN
Sbjct: 730  REAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLDKN 789

Query: 354  KIEKEAEKLEISEKHRGMLEKSNQNLQLEAENLVQRIASKDHELLEKHTEIERLQTLMHG 413
            K+  E +K E+ EK R  +++S ++L    E+L    A K   L E+  ++E+++  +  
Sbjct: 790  KVMIEEQKQEM-EKKRDDMDQSRKSLD---EDLKMMKAQKQ-VLEEEKNKLEQMKIGLER 844

Query: 414  EHSNFIQI----ESALQALQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQG 469
            E     +I    ++  Q L+K+ +  ++E+  LA E+K    +L  ++++ +    ++Q 
Sbjct: 845  EADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLADLQK 904

Query: 470  ---IVEE-----NKTLHELNFSSTRS------LKKQQMEISK------------------ 497
               I+EE     +K + ++     +S      LKK Q E+ K                  
Sbjct: 905  EKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAA 964

Query: 498  -----------LKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQAMLE---- 542
                       LK+  E +E +      E  +L  + + +K D++ L ++   +      
Sbjct: 965  MIREKQNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMKLFRGELQ 1024

Query: 543  --------QLQSLGLNPNSFAASVRDLQNENFML--KETCKKEHSEKEALREKSKDMNEV 592
                      Q+L +  + F   +   +NE      KE  + E+ E +   +++K + E 
Sbjct: 1025 RQRDEVESSRQALIMEKDQFKLKIDHQRNEMSAAFEKEHKRLENMENDLENQRAK-LAES 1083

Query: 593  LMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESM 652
            L + A ME  L  + +EL+  +  V+E++Q   +++ E+  +  EK  +  Q Q I +  
Sbjct: 1084 LNDAAKMEQKLQQMKNELNKEKEQVEEMKQ---MVKTERVKIEQEKEEMRKQTQEIEDGH 1140

Query: 653  QKILENNTVLEKSLSDAKIE---------FEGLRIKSGDLEDCCKLLNDEKNNLQNERSM 703
            +K+ +   + +K L DA +           E L+ +   LE     +  EK +LQN +S 
Sbjct: 1141 EKLQKKTEIADKLLQDANMTTEQNEYRKLIEELQREKEQLEISKNQIEQEKKDLQNMKSN 1200

Query: 704  LISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHSNHKHS 763
            L  QLE +  + +N+E +  N  EK     K+ ++A+ +  E   +  V+ E        
Sbjct: 1201 LERQLESLRHEKANVEDE-KNALEKMRSESKEIQNAIRKEREDLENCWVEIEGEKKRMEE 1259

Query: 764  SEARLA------------------NLEN--------IVRVLQEEQRLG--KVEFEQELDR 795
               RL                   N+E+        +  +LQ +  +G  K E E+E  R
Sbjct: 1260 ETRRLEMHREEIKKVDSELQKSRENIESREEKINNKMEELLQMKVEMGRTKEEIEKESQR 1319

Query: 796  VVNAQIEMFILQNCIEELE-----LKNFVLLTECEKLVEASKFSDKVISELESENLMQLI 850
            + +A I+   L+N   E++      ++ + +   EK  E     DK    L  E  +++ 
Sbjct: 1320 LQDATID---LENAKAEIQRQEDKFEDIIDIKIQEKEREIKIQLDKETKRLSEEIELKVK 1376

Query: 851  EEEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEE---------------IPISRI 895
            + E  +  +++ K +I    G+L+ +       E+K+E+               I I  +
Sbjct: 1377 DLEMEMADMKRQKQEIEDTKGLLEKEKQ-----ELKQEKKELEDQMMDLTQETKIKIIEM 1431

Query: 896  LDKIESLESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLE-----------KKTV 944
              K E  +    K +EE + +  +  +    L Q +S+ E+++ E           KK +
Sbjct: 1432 KTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMI 1491

Query: 945  EQEFENMREQNVILQKDKVELLEENRQLRIEVVN-GVEKEN--RSKSTLAALQAEMIELR 1001
            EQE E++ +    + K + ++ EE  +L  ++    +E+ +   SK  +  L  E+ E R
Sbjct: 1492 EQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQR 1551

Query: 1002 QTNQVFQEE----NGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVLALSNLNLVYE 1057
            +  ++ +EE      K+ DE+  + +N + L++     ++ +  +  +   L  +    E
Sbjct: 1552 KDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEM----E 1607

Query: 1058 IFFTENMVEKRALCEHLG-----NLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIERM 1112
                +   E R++ E        +L  ++ D+N++   L    ++ + E   +N    ++
Sbjct: 1608 AHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQL 1667

Query: 1113 DKELLEMDKRLKAAETSNAEFSRHIEELKMEQEE 1146
             + + E D ++   +  +    + +EE +   EE
Sbjct: 1668 QQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEE 1701



 Score =  159 bits (403), Expect = 5e-37
 Identities = 264/1430 (18%), Positives = 604/1430 (41%), Gaps = 123/1430 (8%)

Query: 315  EMNEERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEK 374
            E+ + ++ L     + L +I K   ++  + EN  +  ++I+ + E++   +     L+ 
Sbjct: 1    ELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKT 60

Query: 375  SNQNLQLEAENLVQRIASKDHELLEKHTEIERLQT----LMHGEHSNFIQIESALQALQK 430
              QNLQ E E   + I     +L  + +E+++ QT    +M    +   Q++   + +++
Sbjct: 61   EIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 120

Query: 431  LYSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGI----VEENKTLHELN----- 481
               + +KE+ N+    K      K ++L KQ F+EE   +    +E  +   E++     
Sbjct: 121  QKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEE 180

Query: 482  FSSTRSLKKQQMEISKLKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQAML 541
              + R  K    ++  +K  K+  E E +   +    L+RE  +I+   +      Q++ 
Sbjct: 181  TQNKRQRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLE 240

Query: 542  EQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDMNEVLMENACMEF 601
            +  + L     SF     D + E  +L +  K  +    A  +K K   E + EN   + 
Sbjct: 241  KMTEELKKEKESFTHLAEDTKKEQEIL-DKVKVANESLMADLQKEKSNLEEMRENISKQT 299

Query: 602  SLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESMQKILENNTV 661
                + ++ + LR    E+ Q    + +++  +  EK  + S+   I ++++ +      
Sbjct: 300  E--DVENKKENLRLREDELWQLQAEIYKQQREIEKEKINIESERAAIIKNVEDLQHKIIS 357

Query: 662  LEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVEEKLSNLEK- 720
            L++     K++ E    +   L+     L  E + ++  +       + VEE  + ++K 
Sbjct: 358  LDRDSESLKLDREAFENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEMTAQIQKD 417

Query: 721  --KVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHSNHKHSSEARLANLENIVRVL 778
              K+ NL E+    +         +E+   SI   K+     KH  E   + L  +   L
Sbjct: 418  RDKINNLIEETNRKDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDL 477

Query: 779  --QEEQRLGKVEFEQELDRVVNAQI--EMFILQNCIEELELKN---FVLLTECEKLVEAS 831
              Q+E  L +++ E+E    +N  I  EM  +++  E++  K      L TE + L +  
Sbjct: 478  EKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQEL 537

Query: 832  KFSDKVISELESE---NLMQLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKE 888
            +   ++I +  S+      +L +++  ++ I +   +  K     Q+D D     E K+E
Sbjct: 538  EKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERK-----QLDKDKEEMEEQKQE 592

Query: 889  EIPISRILD----------KIESLESSLVKSQEEN-QQLLVENSVLLGSLQQHQSEGEKL 937
                   +D          K+  L+  +++ ++ N  ++ V N   +  LQ+ +S  E++
Sbjct: 593  MEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNNLDEMKVANESSMADLQKEKSNLEEM 652

Query: 938  K--LEKKT--VEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKENRS------- 986
            K  + K+T  +E+E + +R +   L++ + E+ ++  +  IE  N +E+E  +       
Sbjct: 653  KENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQQSETEIEKSN-IERERAAIIKDVED 711

Query: 987  -KSTLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDEN---SVM 1042
             +S + +L  +   L+   + F+ E  ++   K  L R   +++  K   + E      M
Sbjct: 712  LQSKIISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEM 771

Query: 1043 FHDVLALSNLNLVYEIFFTENMVE--KRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEA 1100
              D +   N N   ++   + M+E  K+ + +   ++      L+++  +++   +V E 
Sbjct: 772  TADFMETMN-NERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEE 830

Query: 1101 ENVYLNESIERMDKELLEMDKRLKAAETSNAEFSRHIEELKMEQ----EESTKIKENLDR 1156
            E   L +    +++E  E+ K  +  +       +    LK E+    EE  +  + LD+
Sbjct: 831  EKNKLEQMKIGLEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDK 890

Query: 1157 QILEQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLELLNKENEFKL 1216
              +       + +KE   L E  E +  +++ + +E E+ ++RE+ L      K+ + ++
Sbjct: 891  IKVANESTLADLQKEKRILEEMRENISKQIEDIENEKEKSKLREDEL------KKLQTEV 944

Query: 1217 WENEAAAFYHDLQMSSICLALLESKVSELTGVCKILDD-ESSAKSL--ENEHMREIISLL 1273
             + ++        + S   A++  K + +T + K  +D E   K +  E E +    +LL
Sbjct: 945  QKQQSEIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEMQMKEILTEKELLHNDRNLL 1004

Query: 1274 ESEIGGLKEQLSAYVPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVIETCLRKHS 1333
            + ++  L+++L          + D       +L+  K    +    Q++ +     ++H 
Sbjct: 1005 KKDVEDLQQKLMKLFRGELQRQRDEVESSRQALIMEKDQFKLKIDHQRNEMSAAFEKEHK 1064

Query: 1334 HQSARENEI----VLIPDGVSDLLTLQTRIRAV------EKIMMEELKRRVKQKSLTTES 1383
                 EN++      + + ++D   ++ +++ +      EK  +EE+K+ VK + +  E 
Sbjct: 1065 RLENMENDLENQRAKLAESLNDAAKMEQKLQQMKNELNKEKEQVEEMKQMVKTERVKIEQ 1124

Query: 1384 TPYSSLEIATYPK--VENRKKEIELVEENVFDRNSWRKKPKIRLLMKDIPLDR---NVDD 1438
                  +     +   E  +K+ E+ ++ + D N   ++ + R L++++  ++    +  
Sbjct: 1125 EKEEMRKQTQEIEDGHEKLQKKTEIADKLLQDANMTTEQNEYRKLIEELQREKEQLEISK 1184

Query: 1439 QNSKYLKREHRRTNDHVLELCENNEHEPLSAPTVDHAMICHRSD----------DSGRYL 1488
               +  K++ +    ++    E+  HE  +     +A+   RS+          +     
Sbjct: 1185 NQIEQEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLE 1244

Query: 1489 NYSSELDIEK---ELGVDKLELSKSVKEKTEDDKRRILERLSSDGQKL-----AILKMAL 1540
            N   E++ EK   E    +LE+ +   +K + + ++  E + S  +K+      +L+M +
Sbjct: 1245 NCWVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINNKMEELLQMKV 1304

Query: 1541 QDLKKKTETKKKSKQGND--IEYETVKRHIEEVEEAVMQQVSINDQMAKNVEEGASSLDR 1598
            +  + K E +K+S++  D  I+ E  K  I+  E+     + I  Q  +   E    LD+
Sbjct: 1305 EMGRTKEEIEKESQRLQDATIDLENAKAEIQRQEDKFEDIIDIKIQ--EKEREIKIQLDK 1362

Query: 1599 EIPRRGSEQIGKLQFEVQNIQYILLKLAEENNNKVKNRISRKTGILLRRK 1648
            E  R   E    ++ +V++++  +  +  +     K  I    G+L + K
Sbjct: 1363 ETKRLSEE----IELKVKDLEMEMADMKRQ-----KQEIEDTKGLLEKEK 1403


>UniRef100_UPI0000437333 UPI0000437333 UniRef100 entry
          Length = 1850

 Score =  186 bits (472), Expect = 5e-45
 Identities = 291/1591 (18%), Positives = 664/1591 (41%), Gaps = 225/1591 (14%)

Query: 141  ERSSEESNGEVQTLREALAKMQSDKDALFLQ---YQESLENLSKMETDLN-------KAQ 190
            E  S     +++ L++ L  ++ D ++L L    +    E L +M+TDL        K +
Sbjct: 335  ENDSNLLKKDMEDLKQKLMSIERDSESLKLDREAFGNEKEVLKQMKTDLQIQADEIEKIK 394

Query: 191  NNARGLDDRASEAEIQVEILKESLMQLKADKDAGEVLYNQCLETIA-RLESMLSQKDNIE 249
               +    R  E   Q++  ++ +  L  + +  +++ N+    I  +++S+ S KD +E
Sbjct: 395  LETQHDRQRVEEKTAQIQKDRDEINNLIVETNRKDMVLNEMDRDIEEKIKSIQSDKDMLE 454

Query: 250  AKNLKQELTRVVVQKDTVLLQYKQCLEK---------IPMLENKIALAEENSRMLNDQIE 300
             +    E TR  + +    L+ ++ +E+         I    ++I   EE  +   D+++
Sbjct: 455  KERHNLEKTRSELARAKENLETQREIERKDIEKMKKNISREMHEIKHQEEQMKQKQDELD 514

Query: 301  RTELEVETLRKNLAEMNE----ERDSLSVLYHHCLEKISKMENEILHVQENAEQL--KNK 354
            + + E++ L++ L +  E     R  L +     L+K     N+I+   +N  +   K+K
Sbjct: 515  QLKTEIQNLQQELEKEKEIIMKARSQLDLRQSE-LDKQQTNMNDIMETMKNERKQLDKDK 573

Query: 355  IEKEAEKLEIS-EKH-----RGMLEKSNQNLQLEAENLVQRIASKDHELLEKHTEIERLQ 408
             E E +K E+  EKH     R  L++  + ++L+ + + +  +      +E   E + ++
Sbjct: 574  EETEEQKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVIEEEKSKLKQMKIELEREADEIR 633

Query: 409  TLMHGEHSNFIQIESALQALQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQ----DFK 464
             +         + ++  Q  +K+    +KE+ +L+ + K    +L +++++ +    D  
Sbjct: 634  KVKE-------ETQNERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANESTLADIL 686

Query: 465  EEMQGIVEENKTLHELNFSSTRSLKKQQMEISKLKEIKEKLEREFHTSTEESNVLQRETH 524
             E   + E  + + +         +K ++   KLK+++ ++ ++   + +E + ++RE  
Sbjct: 687  RERSNLQEMRENISKQTEDVENKKEKIRLREEKLKQLQAEIHKQQSETEKEKSNIERERA 746

Query: 525  QIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLK---ETCKKEHSEKEA 581
             I  D++ L  +  ++    +SL L+  +F     +L+     L+   +  +K   E + 
Sbjct: 747  AIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLETQH 806

Query: 582  LREKSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTL 641
             R++ ++M    ME          +N+E   L    +E+Q+  Q +++E+  +   + +L
Sbjct: 807  ERQRVEEMTADFMET---------MNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSL 857

Query: 642  LSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNER 701
               L+++    Q I E    LE+   + + E + +R    + ++  + L      L+ E+
Sbjct: 858  DKNLKMMKLQKQVIEEEKNKLEQMKIELEKEADEIRKIKEETQNERQRLEKMTEELKKEK 917

Query: 702  SMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHSNHK 761
                   E  + +   L+K     E   AD++K+K +    +EE+  +I  Q E+    K
Sbjct: 918  ESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSN----LEEMRENISKQTEDSEKEK 973

Query: 762  HSSEARLANLENIVRVLQEEQRLG------KVEFEQELDRVVNAQIEMFILQNCIEELEL 815
                 R   LE +   + ++Q         K+E E+E D +   + E    QN  + LE 
Sbjct: 974  EKIRLREDELEQLQAEIHKQQEEKNKLEQMKIELEREADEISKIKEET---QNKRQRLEK 1030

Query: 816  KNFVLLTECEKLV---EASKFSDKVISELESEN---LMQLIEEEFLLHRIRKFKMDIHKV 869
                L+ E E L    E +K   K++ E++  N   +  L  E+ +L  +R+   +I K+
Sbjct: 1031 MTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRE---NISKL 1087

Query: 870  CGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQE-ENQQLLVENSVLLGSLQ 928
               +        DNE +K ++      D+++ L++ + K Q+ E ++L    S L     
Sbjct: 1088 KEYI--------DNEKEKSKLRE----DELKKLQTEVQKQQKMEREELNQIKSELKRVRS 1135

Query: 929  QHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKENRSKS 988
            +   E +KL  +KK +EQE E+       L+K K E++ + +Q+  E     E +N+ K 
Sbjct: 1136 EIDHEQKKLNDDKKIIEQEKED-------LEKMKSEIMTQRQQMEEE---RSELDNKIKQ 1185

Query: 989  TLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVLA 1048
            T      E  ++  + ++ Q+   K+ +++  +     +L   +    DE  ++  +   
Sbjct: 1186 T----DLERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAK 1241

Query: 1049 LSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENVYLNES 1108
            L N N   +    E   EK  L E     +HL  +  +   V+ +    K+ +   ++  
Sbjct: 1242 LQNENERIKEMDEEIKKEKETLKEME---AHLRKEKEEMRSVIEETQRRKKEDLEKMSTD 1298

Query: 1109 IERMDKELLEMDKRLKAAETSNAEFSRHIEELKMEQEESTKIKENLDRQILEQSENCMNH 1168
            + + +++L+     LK             EE+  +  +  +  +  D Q+ +Q E  +  
Sbjct: 1299 VNKQNQDLMNQRDLLKQER----------EEINHKWTQLQQRIDEFDAQVSKQKEEDLTK 1348

Query: 1169 KKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLELLNKENEFKLWENEAAAFYHDL 1228
            +K++E   ++ E  + ++  +  + E  ++++E        KE E               
Sbjct: 1349 QKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEK------EKEEE--------------- 1387

Query: 1229 QMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMREIISLLESEIGGLKEQLSAYV 1288
                +  A +E K  EL  +   L+   S    E + + +   ++E E   L++  S  +
Sbjct: 1388 ---EVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIM 1444

Query: 1289 PLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVIETCLRKHSHQSARENEIVLIPDG 1348
                 ++E+ + L++                    + +T L +H  ++++E         
Sbjct: 1445 KQRQQMEEERSELDN-------------------KIKQTDLERHDIENSKEI-------- 1477

Query: 1349 VSDLLTLQTRIRAVEKIMMEELKRRVKQKSLTTESTPYSSLEIATYPKVENRKKEIELVE 1408
            V  L+      R   ++  EEL   ++++ +  E      L +    K++N  + I+ ++
Sbjct: 1478 VQKLMVEVEEQRKDIRLQKEELD--IERQKIADEQ----GLVVQNKAKLQNENERIKEMD 1531

Query: 1409 ENVFDRNSWRKKPKIRLLMKDIPLDRNVDDQNSKYLKREHRRTND-HVLELCENNEHEPL 1467
            E +       KK K  L   +  L +  ++  S   + + R+  D   +    N +++ L
Sbjct: 1532 EEI-------KKEKETLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDL 1584

Query: 1468 ---------SAPTVDH--AMICHRSDDSGRYLNYSSELDIEKELGVD------------- 1503
                         ++H    +  R D+    ++   E D+ K+  ++             
Sbjct: 1585 MNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKI 1644

Query: 1504 -----KLELSKSVKEKTEDDKRRILERLSSDGQKLAILKMALQDLKKKTETKKKSKQGND 1558
                 K E  K  KEK ++++  +  ++    ++L  +K  L+ ++ + + ++K    + 
Sbjct: 1645 IEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDK 1704

Query: 1559 IEYETVKRHIEEVEEAVMQQVSINDQMAKNVE-------------EGASSLDREIPRRGS 1605
               E  K  +E+++  +M+Q    ++    +E             E +  + +++     
Sbjct: 1705 KMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQKLMVEVE 1764

Query: 1606 EQIGKLQFEVQNIQYILLKLAEENNNKVKNR 1636
            EQ  ++QF+ + +     K+A+E +  ++N+
Sbjct: 1765 EQKHEIQFQKEELDIERQKIADEQDLLIQNK 1795



 Score =  185 bits (470), Expect = 9e-45
 Identities = 322/1716 (18%), Positives = 710/1716 (40%), Gaps = 220/1716 (12%)

Query: 18   DSHNSPKNSKWLLENLTDIDTKVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYR 77
            +  N  +  K+ L+   D   K+K      + E  S  +  +   K+R +L+ L E   R
Sbjct: 164  EEKNKLEQMKFELQREADEIRKIKEET---QNERQSLEKMTKALIKEREDLVHLAEYTKR 220

Query: 78   AYRALAERY---DHAMGELRHAHKTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPT 134
                L E       +M +L+   + + E   N +                 ++       
Sbjct: 221  EKEMLDEMQVANKSSMADLQREKRILEEMRENIS----------------KQTEDIENEK 264

Query: 135  HRSKKNERSSEESNGEVQTLREAL----AKMQSDKDALFLQYQESLENLSK----METDL 186
             +SK  E   ++   EVQ  +  +      ++S++  +  + Q  +  L K    +E  +
Sbjct: 265  EKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAVMIREKQNMMTELKKKSEDVEIQM 324

Query: 187  NKAQNNARGLDDRASEAEIQVEILKESLMQLKADKDAGEV---LYNQCLETIARLESMLS 243
             +       L++ ++  +  +E LK+ LM ++ D ++ ++    +    E + ++++ L 
Sbjct: 325  KEILTEKELLENDSNLLKKDMEDLKQKLMSIERDSESLKLDREAFGNEKEVLKQMKTDLQ 384

Query: 244  -QKDNIEAKNLKQELTRVVVQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERT 302
             Q D IE   L+ +  R  V++ T  +Q  +       + N I        +LN+     
Sbjct: 385  IQADEIEKIKLETQHDRQRVEEKTAQIQKDR-----DEINNLIVETNRKDMVLNEMDRDI 439

Query: 303  ELEVETLRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKL 362
            E ++++++ +   + +ER +L             +E +    +++ E++K  I +E  ++
Sbjct: 440  EEKIKSIQSDKDMLEKERHNLEKTRSELARAKENLETQREIERKDIEKMKKNISREMHEI 499

Query: 363  EISEKHRGMLEKSNQNLQLEAENLVQRIASKDHELLEKHTEIERLQTLMHGEHSNFIQIE 422
            +  E+     +     L+ E +NL Q +  +   +++  ++++  Q+ +  + +N   I 
Sbjct: 500  KHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIM 559

Query: 423  SALQALQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHELNF 482
              ++  +K   + ++E               +++E  K DF +  + + E+ K +     
Sbjct: 560  ETMKNERKQLDKDKEETEEQK----------QEMEKEKHDFDQSRKSLDEDLKMM----- 604

Query: 483  SSTRSLKKQ--QMEISKLKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQAM 540
                 L+KQ  + E SKLK++K +LERE             E  ++K++ Q+  + ++ M
Sbjct: 605  ----KLQKQVIEEEKSKLKQMKIELERE-----------ADEIRKVKEETQNERQIFEKM 649

Query: 541  LEQLQSLGLNPNSFAASVRDLQNENFMLKE-TCKKEHSEKEALREKSKDMNEVLMENACM 599
             E L+    + +       D + +N +L E     E +  + LRE+S    + + EN   
Sbjct: 650  TEALKKEREDLS------EDAKRKNQVLDEMKVANESTLADILRERSN--LQEMRENISK 701

Query: 600  EFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESMQKILENN 659
            +     + ++ + +R   ++++Q    + +++S    EKS +  +   I + ++ +    
Sbjct: 702  QTE--DVENKKEKIRLREEKLKQLQAEIHKQQSETEKEKSNIERERAAIIKDVEDLQSKI 759

Query: 660  TVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVEEKLSNLE 719
              L++     K++ E    +  +L+     L  E + ++  +     + + VEE  ++  
Sbjct: 760  ISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFM 819

Query: 720  KKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENH--SNHKHSSEARLANLENIVRV 777
            + + N E K   + K+KE    Q +E+      +KE H     + S +  L  ++   +V
Sbjct: 820  ETMNN-ERK--QLNKNKEEMQEQKQEM------EKERHDMDQSRKSLDKNLKMMKLQKQV 870

Query: 778  LQEEQ---RLGKVEFEQELDRVVNAQIEMFILQNCIEELELKNFVLLTECEK---LVEAS 831
            ++EE+      K+E E+E D +   + E    QN  + LE     L  E E    L E +
Sbjct: 871  IEEEKNKLEQMKIELEKEADEIRKIKEE---TQNERQRLEKMTEELKKEKESFTHLAEDT 927

Query: 832  KFSDKVISELESENLMQLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIP 891
            K   K++ +++  N       E L+  ++K K ++ ++   +   ++   D+E +KE+I 
Sbjct: 928  KTEKKILDKMKVAN-------ESLMADLQKEKSNLEEMRENISKQTE---DSEKEKEKIR 977

Query: 892  ISRILDKIESLESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEFENM 951
            +    D++E L++ + K QEE  +L      +   L++   E  K+K E +   Q  E M
Sbjct: 978  LRE--DELEQLQAEIHKQQEEKNKL----EQMKIELEREADEISKIKEETQNKRQRLEKM 1031

Query: 952  REQNV------------------ILQKDKV-------------ELLEENRQ----LRIEV 976
             E+ +                  IL + KV              +LEE R+    L+  +
Sbjct: 1032 TEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENISKLKEYI 1091

Query: 977  VNGVEKENRSKSTLAALQAEM-----IELRQTNQVFQE----------ENGKMLDEKNSL 1021
             N  EK    +  L  LQ E+     +E  + NQ+  E          E  K+ D+K  +
Sbjct: 1092 DNEKEKSKLREDELKKLQTEVQKQQKMEREELNQIKSELKRVRSEIDHEQKKLNDDKKII 1151

Query: 1022 CRNVSDLKDAKSSAEDENSVMFHDVLALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLN 1081
             +   DL+  KS    +   M  +   L N     ++   +    K  + + +  +    
Sbjct: 1152 EQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQR 1211

Query: 1082 NDL---NQEFGVLRKNFEVKEAENVYLNESIERMDKELLEMDKRLKAAETSNAEFSRHIE 1138
             D+    +E  + R+    ++   V     ++  ++ + EMD+ +K  + +  E   H  
Sbjct: 1212 KDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAH-- 1269

Query: 1139 ELKMEQEESTKIKENLDRQILEQSENCMNH-KKEIEHLNEANETLQFEMKTLLHEVEQHR 1197
             L+ E+EE   + E   R+  E  E       K+ + L    + L+ E + + H+  Q +
Sbjct: 1270 -LRKEKEEMRSVIEETQRRKKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQ 1328

Query: 1198 VREEALNLELLNKENEFKLWENEAAAFYHDLQMSSICLALLESKVS-ELTGVCKILDDES 1256
             R +  + ++  ++ E    + +       L+ + I +  +++K   E     K  ++E 
Sbjct: 1329 QRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEE 1388

Query: 1257 SAKS---LENEHMREIISLLE---SEIGGLKEQLSAYVPLVSSLKEDFNSLEHISLLWTK 1310
              ++   ++ E + +I S LE   SEI   +++L+    ++   KED   ++  S +  +
Sbjct: 1389 VMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMK--SEIMKQ 1446

Query: 1311 RNSVVGNGAQKDVVI-ETCLRKHSHQSARENEIVLIPDGVSDLLTLQTRIRAVEKIMMEE 1369
            R  +    ++ D  I +T L +H  ++++E         V  L+      R   ++  EE
Sbjct: 1447 RQQMEEERSELDNKIKQTDLERHDIENSKEI--------VQKLMVEVEEQRKDIRLQKEE 1498

Query: 1370 LKRRVKQKSLTTESTPYSSLEIATYPKVENRKKEIELVEENVFDRNSWRKKPKIRLLMKD 1429
            L   ++++ +  E      L +    K++N  + I+ ++E +       KK K  L   +
Sbjct: 1499 LD--IERQKIADE----QGLVVQNKAKLQNENERIKEMDEEI-------KKEKETLKEME 1545

Query: 1430 IPLDRNVDDQNSKYLKREHRRTNDHVLELCENNEHEPLSAPTVDHAMICHRSDDSGRYLN 1489
              L +  ++  S  ++   RR  + + ++  +   +          +   R + + ++  
Sbjct: 1546 AHLRKEKEEMRS-VIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQ 1604

Query: 1490 YSSELDIEKELGVDKLELSKSVKEKTEDDKRRILERLSSDGQKLAILKMALQDLKKKTET 1549
                +D E +  V K +     K+K  +++R+ LE            K+ + ++K KTE 
Sbjct: 1605 LQQRID-EFDAQVSKQKEEDLTKQKKMEEERKSLEE----------TKIKIIEMKTKTEP 1653

Query: 1550 KKKSKQGNDIEYETVKRHIEEVEEAVMQQVSINDQMAKNVEEGASSL--DREIPRRGSEQ 1607
            +K  K+    E E ++  +E  +E + Q  S  +++   ++     L  D+++  +  E 
Sbjct: 1654 EKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKED 1713

Query: 1608 IGKLQFEVQNIQYILLKLAEENNNKVKNRISRKTGI 1643
            + K++ E+   +  + +   E  NK++     K  I
Sbjct: 1714 LEKMKSEIMKQRQQMEEERSELENKIRQTYIEKCDI 1749



 Score =  185 bits (469), Expect = 1e-44
 Identities = 286/1528 (18%), Positives = 662/1528 (42%), Gaps = 183/1528 (11%)

Query: 136  RSKKNERSSEESNGEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARG 195
            RS+ + R SE    +   + + +  M++++  L    +E  E   +ME + +    + + 
Sbjct: 89   RSELDLRQSELDKQQTN-MNDIIETMKNERKLLDKDKEEMEEQKQEMEKERDNMDQSIKS 147

Query: 196  LDDRASEAEIQVEILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIEAKNLKQ 255
            LD+     ++Q ++++E   +L+  K     L  +  E     E   +++ ++E      
Sbjct: 148  LDEDLKMMKLQKQVIEEEKNKLEQMKFE---LQREADEIRKIKEETQNERQSLE------ 198

Query: 256  ELTRVVVQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAE 315
            ++T+ ++++   L+   +  ++   + +++ +A ++S      ++R +  +E +R+N+++
Sbjct: 199  KMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMA---DLQREKRILEEMRENISK 255

Query: 316  MNEERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGM--LE 373
              E+ ++         +++ K++ E+   Q   +  K  IE E   + I EK   M  L+
Sbjct: 256  QTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESE-RAVMIREKQNMMTELK 314

Query: 374  KSNQNLQLEAENLVQRIASKDHELLEKHTEIERLQTLMHGEHSNFIQIESALQALQKLYS 433
            K +++++++ + ++      + ELLE  + +  L+  M       + IE   ++L KL  
Sbjct: 315  KKSEDVEIQMKEIL-----TEKELLENDSNL--LKKDMEDLKQKLMSIERDSESL-KLDR 366

Query: 434  QSQKEQRNLALELKYGLLLLKD-LELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQQ 492
            ++   ++ +  ++K  L +  D +E  K + + + Q + E+   + +        + +  
Sbjct: 367  EAFGNEKEVLKQMKTDLQIQADEIEKIKLETQHDRQRVEEKTAQIQKDRDEINNLIVETN 426

Query: 493  MEISKLKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQSLGLNPN 552
             +   L E+   +E +  +   + ++L++E H                LE+ +S      
Sbjct: 427  RKDMVLNEMDRDIEEKIKSIQSDKDMLEKERHN---------------LEKTRS------ 465

Query: 553  SFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDMNEVLMENACMEFSLLGLNDELDG 612
              A +  +L+ +             E++ + +  K+++  + E    E  +    DELD 
Sbjct: 466  ELARAKENLETQ----------REIERKDIEKMKKNISREMHEIKHQEEQMKQKQDELDQ 515

Query: 613  LRGTVKEIQQFCQVLQEEKSILADEKSTL---LSQLQIITESMQKILENNTVLEKSLSDA 669
            L+    EIQ   Q L++EK I+   +S L    S+L     +M  I+E      K L   
Sbjct: 516  LK---TEIQNLQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKD 572

Query: 670  KIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEEKY 729
            K E E    +  ++E      +  + +L  +  M+  Q +++EE+ S L++    LE + 
Sbjct: 573  KEETEE---QKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVIEEEKSKLKQMKIELEREA 629

Query: 730  ADVEKDKESAVNQ---VEELFASILVQKENHS-----NHKHSSEARLANLENIVRVLQEE 781
             ++ K KE   N+    E++  ++  ++E+ S      ++   E ++AN   +  +L+E 
Sbjct: 630  DEIRKVKEETQNERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANESTLADILRER 689

Query: 782  QRLGKVEFEQELDRVVNAQIEMFILQNCIEELELKNFVLLTECEKLVEASKFSDKVISEL 841
              L      QE+   ++ Q E   ++N  E++ L+   L     ++ +    ++K  S +
Sbjct: 690  SNL------QEMRENISKQTE--DVENKKEKIRLREEKLKQLQAEIHKQQSETEKEKSNI 741

Query: 842  ESENLMQLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDG--GGDNEIKKEEIPISRILDKI 899
            E E    + + E L  +I     D       L++D +       E+K+ +  + R  D+I
Sbjct: 742  ERERAAIIKDVEDLQSKIISLDRDAES----LKLDREAFENEKEELKQMKTELEREADEI 797

Query: 900  ESLESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQ 959
            E ++   +++Q E Q++     +    ++   +E ++L   K+ ++++ + M ++   + 
Sbjct: 798  EKIK---LETQHERQRV---EEMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMD 851

Query: 960  KDKVELLEENRQLRIEVVNGVEKENRSKSTLAALQAEMIELRQTNQVFQEENGKMLDEKN 1019
            + +  L +  + ++++     E++N+ +     L+ E  E+R+  +  Q       +E+ 
Sbjct: 852  QSRKSLDKNLKMMKLQKQVIEEEKNKLEQMKIELEKEADEIRKIKEETQ-------NERQ 904

Query: 1020 SLCRNVSDLKDAKSS----AEDENSVMFHDVLALSNLNLVYEIFFTENMVEKRALCEHLG 1075
             L +   +LK  K S    AED  +    +   L  + +  E    +   EK  L E   
Sbjct: 905  RLEKMTEELKKEKESFTHLAEDTKT----EKKILDKMKVANESLMADLQKEKSNLEEMRE 960

Query: 1076 NLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIERMDKELLEMDKRLKAAETSNAEFSR 1135
            N+S    D  +E    ++   ++E E   L   I +  +E  ++++     E    E S+
Sbjct: 961  NISKQTEDSEKE----KEKIRLREDELEQLQAEIHKQQEEKNKLEQMKIELEREADEISK 1016

Query: 1136 HIEELKMEQEESTKIKENLDRQ---ILEQSENCMNHKKEIEHLNEANETLQFEMKTLLHE 1192
              EE + +++   K+ E L R+   +   +E+    KK ++ +  ANE+   +++     
Sbjct: 1017 IKEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSI 1076

Query: 1193 VEQHRVREEALNLELLNKENEFKLWENEAAAFYHDLQMSSICLALLESKVSELTGVCKIL 1252
            +E+ R     L   + N++ + KL E+E              L  L+++V +        
Sbjct: 1077 LEEMRENISKLKEYIDNEKEKSKLREDE--------------LKKLQTEVQK-------- 1114

Query: 1253 DDESSAKSLENEHMREIISLLE---SEIGGLKEQLSAYVPLVSSLKEDFNSLEHISLLWT 1309
                  + +E E + +I S L+   SEI   +++L+    ++   KED   ++  S + T
Sbjct: 1115 -----QQKMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMK--SEIMT 1167

Query: 1310 KRNSVVGNGAQKDVVI-ETCLRKHSHQSARENEIVLIPDGVSDLLTLQTRIRAVEKIMME 1368
            +R  +    ++ D  I +T L +H  ++++E         V  L+      R   ++  E
Sbjct: 1168 QRQQMEEERSELDNKIKQTDLERHDIENSKEI--------VQKLMVKVEEQRKDIRLQKE 1219

Query: 1369 ELKRRVKQKSLTTESTPYSSLEIATYPKVENRKKEIELVEENVFDRNSWRKKPKIRLLMK 1428
            EL   ++++ +  E      L +    K++N  + I+ ++E +       KK K  L   
Sbjct: 1220 ELD--IERQKIADE----QGLVVQNKAKLQNENERIKEMDEEI-------KKEKETLKEM 1266

Query: 1429 DIPLDRNVDDQNSKYLKREHRRTNDHVLELCENNEHEPLSAPTVDHAMICHRSDDSGRYL 1488
            +  L +  ++  S  ++   RR  + + ++  +   +          +   R + + ++ 
Sbjct: 1267 EAHLRKEKEEMRS-VIEETQRRKKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWT 1325

Query: 1489 NYSSELDIEKELGVDKLELSKSVKEKTEDDKRRILERLSSDGQKLAILKMALQDLKKKTE 1548
                 +D E +  V K +     K+K  +++R+ LE            K+ + ++K KTE
Sbjct: 1326 QLQQRID-EFDAQVSKQKEEDLTKQKKMEEERKSLEE----------TKIKIIEMKTKTE 1374

Query: 1549 TKKKSKQGNDIEYETVKRHIEEVEEAVMQQVSINDQMAKNVEEGASSL--DREIPRRGSE 1606
             +K  K+    E E ++  +E  +E + Q  S  +++   ++     L  D+++  +  E
Sbjct: 1375 PEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKE 1434

Query: 1607 QIGKLQFEVQNIQYILLKLAEENNNKVK 1634
             + K++ E+   +  + +   E +NK+K
Sbjct: 1435 DLEKMKSEIMKQRQQMEEERSELDNKIK 1462



 Score =  171 bits (434), Expect = 1e-40
 Identities = 267/1389 (19%), Positives = 597/1389 (42%), Gaps = 167/1389 (12%)

Query: 309  LRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEKH 368
            L K  +E+ + ++ L     + L +I K   ++  + EN     ++I+ + E+++  +  
Sbjct: 4    LEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDE 63

Query: 369  RGMLEKSNQNLQLEAENLVQRIASKDHELLEKHTEIERLQTLMHGEHSNFIQ-IESALQA 427
               L+   QNLQ E E   + I     EL  + +E+++ QT M    ++ I+ +++  + 
Sbjct: 64   LDQLKTEIQNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNM----NDIIETMKNERKL 119

Query: 428  LQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRS 487
            L K   + +++++ +  E       +K L+   +  K + Q I EE   L ++ F     
Sbjct: 120  LDKDKEEMEEQKQEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKF----- 174

Query: 488  LKKQQMEISKLKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNE---RYQAMLEQL 544
              + Q E  ++++IKE+ + E  +  + +  L +E    ++D+ HL E   R + ML+++
Sbjct: 175  --ELQREADEIRKIKEETQNERQSLEKMTKALIKE----REDLVHLAEYTKREKEMLDEM 228

Query: 545  QSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDMNEVLMENACMEFSLL 604
            Q          +S+ DLQ E  +L+E        +E + ++++D+     ++   E  L 
Sbjct: 229  QVAN------KSSMADLQREKRILEEM-------RENISKQTEDIENEKEKSKLREDELK 275

Query: 605  GLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQL------------QIITESM 652
             L  E+   +    EI      ++ E++++  EK  ++++L            +I+TE  
Sbjct: 276  KLQTEVQKQQ---SEIDMEKTNIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTE-- 330

Query: 653  QKILENNT-VLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIV 711
            +++LEN++ +L+K + D K +   +   S  L+   +   +EK  L+  ++ L  Q + +
Sbjct: 331  KELLENDSNLLKKDMEDLKQKLMSIERDSESLKLDREAFGNEKEVLKQMKTDLQIQADEI 390

Query: 712  EEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHSNHKHSSEARLANL 771
            E+     +     +EEK A ++KD++   N + E     +V  E         E ++ ++
Sbjct: 391  EKIKLETQHDRQRVEEKTAQIQKDRDEINNLIVETNRKDMVLNE----MDRDIEEKIKSI 446

Query: 772  ENIVRVLQEEQRLGKVEFEQELDRV-VNAQIEMFILQNCIEELELKNFVLLTECEKLVEA 830
            ++   +L E++R    +   EL R   N + +  I +  IE+++      + E +   E 
Sbjct: 447  QSDKDML-EKERHNLEKTRSELARAKENLETQREIERKDIEKMKKNISREMHEIKHQEEQ 505

Query: 831  SKFSDKVISELESE--NLMQLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKE 888
             K     + +L++E  NL Q +E+E  +    + ++D+ +              +E+ K+
Sbjct: 506  MKQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDLRQ--------------SELDKQ 551

Query: 889  EIPISRILDKIESLESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEF 948
            +  ++ I++ +++    L K +EE ++            Q+ + E       +K+++++ 
Sbjct: 552  QTNMNDIMETMKNERKQLDKDKEETEE----------QKQEMEKEKHDFDQSRKSLDEDL 601

Query: 949  ENMREQNVILQKDKVELLEENRQLRIEVVNGVEKENRSKSTLAALQAEMIELRQTNQVFQ 1008
            + M+ Q  +++++K +L    +Q++IE+    ++  + K           E +   Q+F+
Sbjct: 602  KMMKLQKQVIEEEKSKL----KQMKIELEREADEIRKVKE----------ETQNERQIFE 647

Query: 1009 EENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVL-ALSNL-----NLVYEIFFTE 1062
            +    +  E+  L  +           +  N     D+L   SNL     N+  +    E
Sbjct: 648  KMTEALKKEREDLSEDAKRKNQVLDEMKVANESTLADILRERSNLQEMRENISKQTEDVE 707

Query: 1063 NMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIERMDKELLEMDKR 1122
            N  EK  L E    L  L  +++++     K     E E   + + +E +  +++ +D+ 
Sbjct: 708  NKKEKIRLREE--KLKQLQAEIHKQQSETEKEKSNIERERAAIIKDVEDLQSKIISLDRD 765

Query: 1123 LKAAETSNAEFSRHIEELKMEQEESTKIKENLDRQILEQSENCMNHKKEIEHLNEANETL 1182
             ++ +     F    EELK  + E  +  + +++  LE      + ++ +E +     T 
Sbjct: 766  AESLKLDREAFENEKEELKQMKTELEREADEIEKIKLE----TQHERQRVEEM-----TA 816

Query: 1183 QFEMKTLLHEVEQHRVREEALNLELLNKENEFKLWENEAAAFYHDLQMSSICLALLESKV 1242
             F M+T+ +E +Q    +E +  +    E E    +    +   +L+M  +   ++E + 
Sbjct: 817  DF-METMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEK 875

Query: 1243 SELTGVCKILDDESSAKSLENEHMREIISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLE 1302
            ++L  +   L+ E+       E  +     LE     LK++  ++  L    K +   L+
Sbjct: 876  NKLEQMKIELEKEADEIRKIKEETQNERQRLEKMTEELKKEKESFTHLAEDTKTEKKILD 935

Query: 1303 HISLLWTKRNSVVGNGAQKDVVIETC---LRKHSHQSARENEIVLIPDGVSDLLTLQTRI 1359
             + +      S++ +  ++   +E     + K +  S +E E + + +   + L  +   
Sbjct: 936  KMKV---ANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLREDELEQLQAEIHK 992

Query: 1360 RAVEKIMMEELKRRVKQKSLTTESTPYSSLEIATYPKVENRKKEIELVEENVFDRNSWRK 1419
            +  EK  +E++K  +++     E+   S ++  T    +N+++ +E + E +      R+
Sbjct: 993  QQEEKNKLEQMKIELER-----EADEISKIKEET----QNKRQRLEKMTEELI-----RE 1038

Query: 1420 KPKIRLLMKDIPLDRNV-------------DDQNSKYLKREHRRTNDHVLELCENNEHEP 1466
            K  +  L +D   ++ +             D Q  K +  E R     + E  +N + + 
Sbjct: 1039 KESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENISKLKEYIDNEKEK- 1097

Query: 1467 LSAPTVDHAMICHRSDDSGRYLNYSSELDIEKELGVDKLELSKSVKEKTEDDKRRILERL 1526
             S    D            + +       I+ EL   + E+    K K  DDK +I+E+ 
Sbjct: 1098 -SKLREDELKKLQTEVQKQQKMEREELNQIKSELKRVRSEIDHEQK-KLNDDK-KIIEQE 1154

Query: 1527 SSDGQKLAILKMALQDLKKKTETKKKSKQGNDIEYETVKRHIEEVEEAVMQQVSIN-DQM 1585
              D +K   +K  +   +++ E +++S+  N I+   ++RH  E  + ++Q++ +  ++ 
Sbjct: 1155 KEDLEK---MKSEIMTQRQQME-EERSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQ 1210

Query: 1586 AKNVEEGASSLDREIPRRGSEQ------IGKLQFEVQNIQYILLKLAEENNNKVKNRISR 1639
             K++      LD E  +   EQ        KLQ E + I     K  +E   K K  +  
Sbjct: 1211 RKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERI-----KEMDEEIKKEKETLKE 1265

Query: 1640 KTGILLRRK 1648
                L + K
Sbjct: 1266 MEAHLRKEK 1274



 Score =  166 bits (420), Expect = 6e-39
 Identities = 269/1344 (20%), Positives = 569/1344 (42%), Gaps = 189/1344 (14%)

Query: 38   TKVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAE---RYDHAMGELR 94
            +K+K M   +E EAD   +  E    +R    K+ E   +    L+E   R +  + E++
Sbjct: 616  SKLKQMKIELEREADEIRKVKEETQNERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMK 675

Query: 95   HAHKT---------------------MPEAFPNSAYYILNDDSPCGSLGPDAESHTSARP 133
             A+++                       E   N    I   +     L   AE H     
Sbjct: 676  VANESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLREEKLKQL--QAEIHKQQSE 733

Query: 134  THRSKKN-ERSSEESNGEVQTLREALAKMQSDKDALFLQ---YQESLENLSKMETDLNKA 189
            T + K N ER       +V+ L+  +  +  D ++L L    ++   E L +M+T+L + 
Sbjct: 734  TEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELERE 793

Query: 190  QNNARGLDDRASEAEIQVEILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIE 249
                    D   + +++ +  ++ + ++ AD    E + N+  +     E M  QK  +E
Sbjct: 794  A-------DEIEKIKLETQHERQRVEEMTAD--FMETMNNERKQLNKNKEEMQEQKQEME 844

Query: 250  AKNLKQELTRVVVQKDTVLLQYKQCL---EKIPMLENKIALAEENSRMLNDQIERTELEV 306
             +    + +R  + K+  +++ ++ +   EK  + + KI L +E      D+I + + E 
Sbjct: 845  KERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMKIELEKEA-----DEIRKIKEET 899

Query: 307  ETLRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHVQENA-EQLKNKIEKEAEKLEIS 365
            +  R+ L +M EE       + H  E  +K E +IL   + A E L   ++KE   LE  
Sbjct: 900  QNERQRLEKMTEELKKEKESFTHLAED-TKTEKKILDKMKVANESLMADLQKEKSNLEEM 958

Query: 366  E----KHRGMLEKSNQNLQLEAENLVQRIASKDHELLEKHTEIERLQTLMHGEHSNFIQI 421
                 K     EK  + ++L  + L Q + ++ H+  E+  ++E+++  +  E     +I
Sbjct: 959  RENISKQTEDSEKEKEKIRLREDELEQ-LQAEIHKQQEEKNKLEQMKIELEREADEISKI 1017

Query: 422  ----ESALQALQKLYSQSQKEQRNLAL---ELKYGLLLLKDLELSKQ----DFKEEMQGI 470
                ++  Q L+K+  +  +E+ +LA    + K    +L +++++ +    D + E   +
Sbjct: 1018 KEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSIL 1077

Query: 471  VEENKTLHELNFSSTRSLKKQQMEISKLKEIKEKLEREFHTSTEESNVLQRETHQIKDDI 530
             E  + + +L        +K ++   +LK+++ +++++     EE N ++ E  +++ +I
Sbjct: 1078 EEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQKMEREELNQIKSELKRVRSEI 1137

Query: 531  QH----LNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKS 586
             H    LN+  + + ++ + L    +      + ++ E   L    K+   E+  + E S
Sbjct: 1138 DHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDI-ENS 1196

Query: 587  KDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQ 646
            K++ + LM         + + ++   +R   +E+    Q + +E+ ++   K+ L ++ +
Sbjct: 1197 KEIVQKLM---------VKVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENE 1247

Query: 647  IITESMQKILENNTVLEKSLSDAKIEFEGLRI--------KSGDLEDCCKLLNDEKNNLQ 698
             I E  ++I +    L++  +  + E E +R         K  DLE     +N +  +L 
Sbjct: 1248 RIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDVNKQNQDLM 1307

Query: 699  NERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHS 758
            N+R +L  + E +  K + L++++   +   A V K KE  + +          QK+   
Sbjct: 1308 NQRDLLKQEREEINHKWTQLQQRIDEFD---AQVSKQKEEDLTK----------QKKMEE 1354

Query: 759  NHKHSSEARLANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQNCIEELE-LKN 817
              K   E ++  +E  ++   E +++ K E E+E + V+ A++EM       EEL+ +K+
Sbjct: 1355 ERKSLEETKIKIIE--MKTKTEPEKIKK-EKEKEEEEVMRAKVEMKK-----EELDQIKS 1406

Query: 818  FVLLTECEKLVEASKFSD-KVISELESENLMQLIEEEFLLHRIRKFKMDIHKVCGVLQID 876
             +     E   E  K +D K + E E E+L ++  E      I K +  + +    L   
Sbjct: 1407 QLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSE------IMKQRQQMEEERSEL--- 1457

Query: 877  SDGGGDNEIKKEEIPISRILDKIESLESSLVKSQE--------------ENQQLLVENSV 922
                 DN+IK+ ++    I +  E ++  +V+ +E              E Q++  E  +
Sbjct: 1458 -----DNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGL 1512

Query: 923  LLGSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEK 982
            ++ +  + Q+E E++K   + +++E E ++E    L+K+K    EE R + IE     +K
Sbjct: 1513 VVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEK----EEMRSV-IEETQRRQK 1567

Query: 983  ENRSKSTLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSV- 1041
            E+  K +    +     + Q + + QE   + ++ K +  +   D  DA+ S + E  + 
Sbjct: 1568 EDLEKMSTDVNKQNQDLMNQRDLLKQER--EEINHKWTQLQQRIDEFDAQVSKQKEEDLT 1625

Query: 1042 ----MFHDVLALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEV 1097
                M  +  +L    +      T+   EK                  +E  V+R   E+
Sbjct: 1626 KQKKMEEERKSLEETKIKIIEMKTKTEPEKIK-----------KEKEKEEEEVMRAKVEM 1674

Query: 1098 KEAENVYLNESIERMDKELLEMDKRLKAAETSNAEFSRHIEELKMEQEESTKIKENLDRQ 1157
            K+ E   +   +ER+  E+    K+L   +    +    +E++K E  +  +  E    +
Sbjct: 1675 KKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSE 1734

Query: 1158 ILEQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLELLNKENEFKLW 1217
            +  +       K +IE+  E  + L  E++   HE++    ++E L++E     +E  L 
Sbjct: 1735 LENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQ---FQKEELDIERQKIADEQDL- 1790

Query: 1218 ENEAAAFYHDLQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMREIISLLESEI 1277
                               L+++K SEL    + + + +     E E ++E+ + LE E 
Sbjct: 1791 -------------------LIQNK-SELQNENERIKNINEVIKKERETLKEMEAYLEKE- 1829

Query: 1278 GGLKEQLSAYVPLVSSLKEDFNSL 1301
               KE++ +        KED   +
Sbjct: 1830 ---KEEMKSITEETRRQKEDLEKM 1850



 Score =  157 bits (397), Expect = 3e-36
 Identities = 226/1064 (21%), Positives = 461/1064 (43%), Gaps = 188/1064 (17%)

Query: 39   KVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDHAMGELRHAHK 98
            K++ M   +E+EAD   +  E    +R  L K+ EE  +      E + H   + +   K
Sbjct: 877  KLEQMKIELEKEADEIRKIKEETQNERQRLEKMTEELKKE----KESFTHLAEDTKTEKK 932

Query: 99   TMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSK--KNERSSEESNGEVQTLRE 156
             + +        + N+     SL  D +   S     R    K    SE+   +++   +
Sbjct: 933  ILDKM------KVANE-----SLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLRED 981

Query: 157  ALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDDRASEAEIQVEILKESLMQ 216
             L ++Q++      + QE    L +M+ +L +  +    + +       ++E + E L++
Sbjct: 982  ELEQLQAE----IHKQQEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIR 1037

Query: 217  LKADKDAGEVLYNQCLETIARL-ESMLSQKDNIEAKNLKQELTRVVVQKDTVLLQYKQCL 275
             K              E++A L E   ++K  ++   +  E +   +Q++  +L+  +  
Sbjct: 1038 EK--------------ESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILE--EMR 1081

Query: 276  EKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEERDSLSVLYHHCLEKIS 335
            E I  L+  I   +E S++  D++++ + EV+  +K       ER+ L+ +      ++ 
Sbjct: 1082 ENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQKM------EREELNQIK----SELK 1131

Query: 336  KMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQLEAENLVQRIASKDH 395
            ++ +EI H Q+     K  IE+E E LE   K +  +    Q ++ E   L  +I   D 
Sbjct: 1132 RVRSEIDHEQKKLNDDKKIIEQEKEDLE---KMKSEIMTQRQQMEEERSELDNKIKQTD- 1187

Query: 396  ELLEKHTEIERLQTLMHGEHSNFIQIESALQALQKLYSQSQKEQRNLALELKYGLLLLKD 455
              LE+H                   IE++ + +QKL  + +++++++ L+ +       +
Sbjct: 1188 --LERH------------------DIENSKEIVQKLMVKVEEQRKDIRLQKE-------E 1220

Query: 456  LELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEISKLKEIKEKLEREFHTSTEE 515
            L++ +Q   +E QG+V +NK              K Q E  ++KE+ E++++E  T  E 
Sbjct: 1221 LDIERQKIADE-QGLVVQNKA-------------KLQNENERIKEMDEEIKKEKETLKEM 1266

Query: 516  SNVLQRETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKE 575
               L++E  +++  I+    R +  LE++ S  +N  +     +DL N+  +LK+     
Sbjct: 1267 EAHLRKEKEEMRSVIEETQRRKKEDLEKM-STDVNKQN-----QDLMNQRDLLKQ----- 1315

Query: 576  HSEKEALREKSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILA 635
              E+E +  K   + + +              DE D      KE     Q   EE+    
Sbjct: 1316 --EREEINHKWTQLQQRI--------------DEFDAQVSKQKEEDLTKQKKMEEERKSL 1359

Query: 636  DEKSTLLSQLQIITESMQKILENNTVLEKSLSDAKIEF---EGLRIKSG----------- 681
            +E    + +++  TE  +KI +     E+ +  AK+E    E  +IKS            
Sbjct: 1360 EETKIKIIEMKTKTEP-EKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHE 1418

Query: 682  --DLEDCCKLLNDEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKE-- 737
               L D  K++  EK +L+  +S ++ Q + +EE+ S L+ K+   + +  D+E  KE  
Sbjct: 1419 QKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIV 1478

Query: 738  -SAVNQVEELFASILVQKE--NHSNHKHSSEARLANLENIVRVLQEEQRLGKVEFEQELD 794
               + +VEE    I +QKE  +    K + E  L  ++N  ++  E +R+ +++ E + +
Sbjct: 1479 QKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLV-VQNKAKLQNENERIKEMDEEIKKE 1537

Query: 795  RVVNAQIEMFILQNCIEELELKNFVLLTECEKLVEASKFSDKVISE----LESENLMQLI 850
            +    ++E  + +   E+ E+++ +  T+  +  +  K S  V  +    +   +L++  
Sbjct: 1538 KETLKEMEAHLRK---EKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQE 1594

Query: 851  EEEF------LLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKE-------EIPISRILD 897
             EE       L  RI +F   + K     Q + D     ++++E       +I I  +  
Sbjct: 1595 REEINHKWTQLQQRIDEFDAQVSK-----QKEEDLTKQKKMEEERKSLEETKIKIIEMKT 1649

Query: 898  KIESLESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLE-----------KKTVEQ 946
            K E  +    K +EE + +  +  +    L Q +S+ E+++ E           KK +EQ
Sbjct: 1650 KTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQ 1709

Query: 947  EFENMREQNVILQKDKVELLEENRQLRIEV----VNGVEKENRSKSTLAALQAEMIELRQ 1002
            E E++ +    + K + ++ EE  +L  ++    +   + EN SK  +  L  E+ E + 
Sbjct: 1710 EKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKCDIEN-SKEIVQKLMVEVEEQKH 1768

Query: 1003 TNQVFQE----ENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVM 1042
              Q  +E    E  K+ DE++ L +N S+L++     ++ N V+
Sbjct: 1769 EIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKNINEVI 1812



 Score =  128 bits (321), Expect = 2e-27
 Identities = 200/990 (20%), Positives = 427/990 (42%), Gaps = 145/990 (14%)

Query: 18   DSHNSPKNSKWLLENL---TDIDTKVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEE 74
            D      N + + EN+   T+   K K  I+L E+E +          +++ +L ++  E
Sbjct: 947  DLQKEKSNLEEMRENISKQTEDSEKEKEKIRLREDELEQLQAEIHKQQEEKNKLEQMKIE 1006

Query: 75   FYRAYRALAERYDHAMGELRHAHKTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPT 134
              R    +++  +    + +   K   E        ++ +      L  D         T
Sbjct: 1007 LEREADEISKIKEETQNKRQRLEKMTEE--------LIREKESLAHLAED---------T 1049

Query: 135  HRSKKNERSSEESNGEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNAR 194
               KK     + +N        ++A +Q +K  L    +E  EN+SK++  ++  +  ++
Sbjct: 1050 KTEKKILDEMKVAN------ESSMADLQREKSIL----EEMRENISKLKEYIDNEKEKSK 1099

Query: 195  GLDDRASEAEIQVEILKESLMQLKADKDAGEVLYNQCLETIARLESMLS---QKDNIEAK 251
              +D   +  +Q E+ K+  M+ +          NQ    + R+ S +    +K N + K
Sbjct: 1100 LREDELKK--LQTEVQKQQKMEREE--------LNQIKSELKRVRSEIDHEQKKLNDDKK 1149

Query: 252  NLKQELTRVVVQKDTVLLQYKQCLEKIPMLENKIALAE------ENSRMLNDQIERTELE 305
             ++QE   +   K  ++ Q +Q  E+   L+NKI   +      ENS+ +   +++  ++
Sbjct: 1150 IIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKEI---VQKLMVK 1206

Query: 306  VETLRKNLA----EMNEERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEK 361
            VE  RK++     E++ ER  ++      ++  +K++NE     E  +++  +I+KE E 
Sbjct: 1207 VEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNE----NERIKEMDEEIKKEKET 1262

Query: 362  LEISEKHRGMLEKSNQNLQLEAENLVQRIASKDHELLEKHTEIERLQTLMHGEHSNFIQI 421
            L+  E H   L K  + ++   E   +R          K  ++E++ T ++ ++ + +  
Sbjct: 1263 LKEMEAH---LRKEKEEMRSVIEETQRR----------KKEDLEKMSTDVNKQNQDLMNQ 1309

Query: 422  ESALQALQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHELN 481
               L+  ++  +    + +    E    +   K+ +L+KQ   EE      E K+L E  
Sbjct: 1310 RDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEE------ERKSLEETK 1363

Query: 482  FSSTRSLKKQQMEISKLKEIKEKLEREF-----HTSTEESNVLQRETHQIKDDIQH---- 532
                    K + E  K+K+ KEK E E          EE + ++ +  +++ +I H    
Sbjct: 1364 IKIIEMKTKTEPE--KIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKK 1421

Query: 533  LNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDMNEV 592
            LN+  + + ++ + L    +      + ++ E   L    K+   E+  + E SK++ + 
Sbjct: 1422 LNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDI-ENSKEIVQK 1480

Query: 593  LMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESM 652
            LM         + + ++   +R   +E+    Q + +E+ ++   K+ L ++ + I E  
Sbjct: 1481 LM---------VEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMD 1531

Query: 653  QKILENNTVLEKSLSDAKIEFEGLRI--------KSGDLEDCCKLLNDEKNNLQNERSML 704
            ++I +    L++  +  + E E +R         +  DLE     +N +  +L N+R +L
Sbjct: 1532 EEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLL 1591

Query: 705  ISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHSNHKHSS 764
              + E +  K + L++++   +   A V K KE  + +          QK+     K   
Sbjct: 1592 KQEREEINHKWTQLQQRIDEFD---AQVSKQKEEDLTK----------QKKMEEERKSLE 1638

Query: 765  EARLANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFI--LQNCIEELELKNFVL-- 820
            E ++  +E  ++   E +++ K E E+E + V+ A++EM    L     +LE     +  
Sbjct: 1639 ETKIKIIE--MKTKTEPEKIKK-EKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDH 1695

Query: 821  ----LTECEKLVEASKFS-DKVISELESENLMQLIEEEFLLHRIRKF---KMDIH---KV 869
                L + +K++E  K   +K+ SE+  +      E   L ++IR+    K DI    ++
Sbjct: 1696 EQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEI 1755

Query: 870  CGVLQID-SDGGGDNEIKKEEIPISR--ILDKIESLESSLVKSQEENQQLLVENSVL--- 923
               L ++  +   + + +KEE+ I R  I D+ + L  +  + Q EN+++   N V+   
Sbjct: 1756 VQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKE 1815

Query: 924  LGSLQQHQSEGEKLKLEKKTVEQEFENMRE 953
              +L++ ++  EK K E K++ +E    +E
Sbjct: 1816 RETLKEMEAYLEKEKEEMKSITEETRRQKE 1845



 Score =  116 bits (290), Expect = 7e-24
 Identities = 221/1060 (20%), Positives = 456/1060 (42%), Gaps = 151/1060 (14%)

Query: 717  NLEKKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHS----NHKHSSEARLANLE 772
            NLEK  + L +   D+EK KE+ + ++++    +    EN +      KH  E      +
Sbjct: 3    NLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITIEMHEIKHQEEQMKQKQD 62

Query: 773  NIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQNCIEELELKNFVLLTECEKLVEASK 832
             + ++  E Q L + E E+E + ++  + E+ + Q+   EL+ +   +    E +    K
Sbjct: 63   ELDQLKTEIQNL-QQELEKEKEIIMKDRSELDLRQS---ELDKQQTNMNDIIETMKNERK 118

Query: 833  FSDKVISELES---------ENLMQLI---EEEFLLHRIRK-----FKMDIHKVCGVLQI 875
              DK   E+E          +N+ Q I   +E+  + +++K      K  + ++   LQ 
Sbjct: 119  LLDKDKEEMEEQKQEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQR 178

Query: 876  DSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLV----ENSVLLGSLQQHQ 931
            ++D     EI+K +         +E +  +L+K +E+   L      E  +L      ++
Sbjct: 179  EAD-----EIRKIKEETQNERQSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANK 233

Query: 932  SEGEKLKLEKKTVEQEFENMREQ--NVILQKDKVELLE-ENRQLRIEVVNGVEKENRSKS 988
            S    L+ EK+ +E+  EN+ +Q  ++  +K+K +L E E ++L+ EV     + +  K+
Sbjct: 234  SSMADLQREKRILEEMRENISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKT 293

Query: 989  TLAALQAEMI--------ELRQTNQVFQEENGKMLDEK-------NSLCRNVSDLKDAKS 1033
             + + +A MI        EL++ ++  + +  ++L EK       N L +++ DLK    
Sbjct: 294  NIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQKLM 353

Query: 1034 SAEDENSVMFHDVLALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRK 1093
            S E ++  +  D  A  N   V +   T+  ++   + +      H    + ++   ++K
Sbjct: 354  SIERDSESLKLDREAFGNEKEVLKQMKTDLQIQADEIEKIKLETQHDRQRVEEKTAQIQK 413

Query: 1094 NFEVKEAENVYLNESIERMDKELLEMDK----RLKAAETSNAEFSRHIEELKMEQEESTK 1149
            + +  E  N+ +  +  R D  L EMD+    ++K+ ++      +    L+  + E  +
Sbjct: 414  DRD--EINNLIVETN--RKDMVLNEMDRDIEEKIKSIQSDKDMLEKERHNLEKTRSELAR 469

Query: 1150 IKENLDRQ-------ILEQSENCMNHKKEIEHLNEAN-------ETLQFEMKTLLHEVEQ 1195
             KENL+ Q       I +  +N      EI+H  E         + L+ E++ L  E+E+
Sbjct: 470  AKENLETQREIERKDIEKMKKNISREMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEK 529

Query: 1196 HR-----------VREEALNLELLNKENEFKLWENEAAAFYHDLQMSSICLALLESKVSE 1244
             +           +R+  L+ +  N  +  +  +NE      D + +      +E +  +
Sbjct: 530  EKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHD 589

Query: 1245 LTGVCKILDDESSAKSLENEHMREIISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLEHI 1304
                 K LD++     L+    +++I   +S++  +K +L      +  +KE+  +   I
Sbjct: 590  FDQSRKSLDEDLKMMKLQ----KQVIEEEKSKLKQMKIELEREADEIRKVKEETQNERQI 645

Query: 1305 -----SLLWTKRNSVVGNGAQKDVVIE-----------TCLRKHSH-QSARENEIVLIPD 1347
                   L  +R  +  +  +K+ V++             LR+ S+ Q  REN    I  
Sbjct: 646  FEKMTEALKKEREDLSEDAKRKNQVLDEMKVANESTLADILRERSNLQEMREN----ISK 701

Query: 1348 GVSDLLTLQTRIRAVEKIMMEELKRRVKQKSLTTESTPYSSLEIATYPK-VENRKKEIEL 1406
               D+   + +IR  E+ + +      KQ+S T +       E A   K VE+ + +I  
Sbjct: 702  QTEDVENKKEKIRLREEKLKQLQAEIHKQQSETEKEKSNIERERAAIIKDVEDLQSKIIS 761

Query: 1407 VEENV----FDRNSWRKKPKIRLLMKDIPLDRNVDDQNSKYLKREH--RRTNDHVLELCE 1460
            ++ +      DR ++  + K  L      L+R  D+     L+ +H  +R  +   +  E
Sbjct: 762  LDRDAESLKLDREAFENE-KEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFME 820

Query: 1461 --NNEH-------EPLSAPTVDHAMICHRSDDSGRYLNYSSE-LDIEKEL---GVDKLEL 1507
              NNE        E +     +     H  D S + L+ + + + ++K++     +KLE 
Sbjct: 821  TMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQ 880

Query: 1508 SKSVKEKTEDDKRRILERLSSDGQKLAIL-------KMALQDLKKKTETKK----KSKQG 1556
             K   EK  D+ R+I E   ++ Q+L  +       K +   L + T+T+K    K K  
Sbjct: 881  MKIELEKEADEIRKIKEETQNERQRLEKMTEELKKEKESFTHLAEDTKTEKKILDKMKVA 940

Query: 1557 ND---IEYETVKRHIEEVEEAVMQQVSINDQMAKNV---EEGASSLDREIPRRGSE--QI 1608
            N+    + +  K ++EE+ E + +Q   +++  + +   E+    L  EI ++  E  ++
Sbjct: 941  NESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLREDELEQLQAEIHKQQEEKNKL 1000

Query: 1609 GKLQFEVQNIQYILLKLAEENNNKVKNRISRKTGILLRRK 1648
             +++ E++     + K+ EE  NK + R+ + T  L+R K
Sbjct: 1001 EQMKIELEREADEISKIKEETQNK-RQRLEKMTEELIREK 1039


>UniRef100_UPI0000432990 UPI0000432990 UniRef100 entry
          Length = 1433

 Score =  183 bits (465), Expect = 3e-44
 Identities = 280/1340 (20%), Positives = 575/1340 (42%), Gaps = 174/1340 (12%)

Query: 29   LLENLTDIDTKVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDH 88
            L + L + +  +K  +  +E   DS +       ++R  L+   E   R         ++
Sbjct: 126  LNKQLNEDNESMKRTMGNLEARIDSLSNELSNVERERDALLDENESVKRELERTLTENEN 185

Query: 89   AMGELRHAHKTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKNERSSEESN 148
               EL  A + + +          N D+         E+ T        K +   S+   
Sbjct: 186  LKTELDKADEQLDKLKTERNELQRNFDTM------KLENETLKENVKALKDDLEESKREV 239

Query: 149  GEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDDRASEAEIQVE 208
             E++ + +AL   +  KDA F + Q++++NL     +L K  ++ R    R+SE E +++
Sbjct: 240  DEMKAVGDALKDKEELKDAEFRELQQNMQNLKTENGELKKENDDLR---TRSSELEHKLD 296

Query: 209  ILKESL----------------MQLKADKDAGEVLYNQCLETIARLESMLS------QKD 246
             +K+ L                ++ + +KD  E+   Q    I+ L+  L       +K 
Sbjct: 297  NVKKELDKVESENADLRAKIDNLEKELEKDKKEI--EQLKLEISSLKDALDKCVDEMEKL 354

Query: 247  NIEAKNLKQELTRVVVQ--KDTVLLQYK--QCLEKIPMLENKIALAEENSRMLNDQIERT 302
             +E + LK+E  +V     ++ V L+ K  +  E +    N++      +  L  ++ R 
Sbjct: 355  KVENEKLKKEGMKVEATWLEENVNLKAKNTELEENLANTVNELDKMRSENADLLSELNRL 414

Query: 303  ELEVETLRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHVQENAE------------- 349
            + E+E+ RK + ++  E  S+      C+++I K++ E   ++   +             
Sbjct: 415  KQELESGRKEIDQLKSEIGSMKDALGKCVDEIEKLKTENKDLKSEVQGLESERDRLTNEV 474

Query: 350  -QLKNKIEKEAEKLEISEKHRGMLEKSNQNLQLEAENLVQRIASKDHELLEKHTEIERLQ 408
              LK KI +  EKL  + K     +  + +L+ E + L + + S   E+ +   E   + 
Sbjct: 475  ADLKPKISELQEKLTDASKKLDEAKTEDSDLRAEVDRLKKELESAGKEIDQLKAE---MN 531

Query: 409  TLMHGEHSNFIQIESALQALQKLYSQ---SQKEQRNLALELKYGLLLLKDLELSKQDFKE 465
            +L +G +    ++E       +L SQ    + E  +LA EL      +KD   + +D K+
Sbjct: 532  SLKNGLNKCVEEMEKLTNENSELKSQVHGLRGEGDSLASELTN----VKDENSALKDEKD 587

Query: 466  EMQGIVEENKTLHELNFSSTRSLKKQQMEISKLKEIKEKLEREFHTSTEESNVLQRETHQ 525
            ++   + ENKT +E        LKKQ  E   L+    K+++E  +   E+N L+ E ++
Sbjct: 588  QLNKQLAENKTENE-------RLKKQNDE---LESENTKIKKELESCKNENNNLKEENNK 637

Query: 526  IKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREK 585
            +K++++ L E+ +++ ++   L          ++ L+ +    +   +K  +E   LR +
Sbjct: 638  LKEELEKLGEQLKSLNDETNKLRRELKEAEDKIQILEPQLSRARSENEKSQNELAVLRNE 697

Query: 586  SKD----MNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEE----KSILADE 637
            + +    ++  +++N  M  +L  L D++  L   +   ++    L+EE    K+ L+D 
Sbjct: 698  ANELKVKLDREMLDNTNMRNALKILEDQVLDLNKKLDNCREENDALKEENKDLKTKLSDT 757

Query: 638  KSTLLS------QLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLN 691
               +L+       L+    S+QK +E    L++ ++D + E +  ++     E C     
Sbjct: 758  GQVVLNLKTECDNLKEDIASLQKTIEQ---LKQKIADQEAEIDHWKV-----EHC----- 804

Query: 692  DEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASIL 751
              K  L NE+  L + LE V   L +L + +  L+ +  D+ K+     +Q++    S+ 
Sbjct: 805  --KFELDNEK--LKADLEKV---LKDLNEYLIKLKNEKDDLNKNMTDLTSQLDRQKRSLE 857

Query: 752  VQKENHSNHKHSSEARLANLENIVRVLQ---EEQRLGKVEFEQELD----RVVNAQIEMF 804
             +K    + K   + ++A+L + +  L+   E+ R    +++ E+D    ++ +A+ E  
Sbjct: 858  AEK----SAKDRGDVQIASLNSELEALKKELEKLRADNSKYKSEIDDLGKQLASAKNE-- 911

Query: 805  ILQNCIEE---LELKNFVLLTECEKLVEASKFSDKVISELE---SENLMQLIEEEFLLHR 858
             L +C EE   L+  N  L +E + L        ++ +EL+   SEN   L ++  L   
Sbjct: 912  -LNDCREEIVVLKNANSALRSELDPLRSLKDDYSRLTTELDGLKSENTKLLQDKRSLEDE 970

Query: 859  IRKFKMDIHKVCGVLQIDSDGGGDN-EIKKEEIPISRILDKIESLESSLVKSQEENQQLL 917
              K +              +G G   EI +    +       E L+S L   ++EN +L 
Sbjct: 971  FGKLR-------------GEGDGQRVEIDRLRTTLDAEKTAAEKLKSDLQSCKDENDKLQ 1017

Query: 918  VENSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVV 977
             + + +  SL +  +E ++LK E     ++ E+M  +   L+     L  E  +L     
Sbjct: 1018 TQINEMKRSLDKMGTENDRLKREVDESRKKLEDMEAKVKSLENQLSNLSAEKEEL----- 1072

Query: 978  NGVEKENRSKSTLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAED 1037
              V++  R++  L  L+ E+ +        ++E+  + +E  +L   ++  +D     ++
Sbjct: 1073 --VKELYRTREDLNNLRNELEKQTGVKDTMEKESTNLKEELKALKEELNKTRDENDRLKN 1130

Query: 1038 ENSVMFHDVLALS-NLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFE 1096
            EN  +  ++  L+  L+ + +        E   L   + NL+  N +L++E  V + N  
Sbjct: 1131 ENDKLNAEIARLNKQLDALKD--------ESANLKNDIENLNERNAELSKELAVAKDNLM 1182

Query: 1097 VKEA-------ENVYLNESIERMDKELLEMDKRLKAAETSNAEFSRHIEELKMEQEESTK 1149
              E        EN  +   I  ++  + E+D   +  + +  E  +   EL   +  + K
Sbjct: 1183 GMETRLSNLKKENDDMKNKIITLEDSIQEVDDLKRQLKEAKKELDKPSPELDTLKSTNKK 1242

Query: 1150 IKENLDRQILEQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLEL-- 1207
            ++++LD    E     +N K ++++L      LQ E+  +  E +  R R  AL  +L  
Sbjct: 1243 LQDDLDNARNES----LNLKNDLDNLQNDYNNLQTELADVKEERDTFRERAAALEKDLVR 1298

Query: 1208 LNKENEFKLWENEAAAFYHD--LQMSSICLALLESKVSELTGVCKILDDESSAKSLENEH 1265
            + +ENE  + +NE      D     ++  L  LE   SE     K+ D+  +A+S E E 
Sbjct: 1299 VKRENEELVEQNETLRTELDDCRGENNRLLKELEKLKSENV---KLQDNLINARS-EGER 1354

Query: 1266 MREIISLLESEIGGLKEQLS 1285
            ++E ++ L+ +   L+  L+
Sbjct: 1355 LKEDLNKLKKDYSDLRTDLT 1374



 Score =  176 bits (447), Expect = 4e-42
 Identities = 306/1534 (19%), Positives = 652/1534 (41%), Gaps = 192/1534 (12%)

Query: 145  EESNGEVQTLREALAKMQS---DKDALFLQYQESLENLSKMETDLNKAQNNARGLDDRAS 201
            E+   E++  R    ++++   D DAL    ++ L  L K  ++L K   + RG  +R  
Sbjct: 10   EDLRNELEDQRAKNKELEACCKDMDAL----EKKLSELEKKRSELEKELEDNRGELERLQ 65

Query: 202  EAEIQVEILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIEAKNLKQELTRVV 261
            +  +    LK+ +   +A+KD    L           ES   ++DN   +NL  +L R+ 
Sbjct: 66   KENLD---LKDVIEVERAEKDKLRDLLE---------ESKKLKEDN---ENLWAQLERLR 110

Query: 262  VQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEERD 321
             + D ++ Q K+ LE +    NK  L E+N  M    +   E  +++L   L+ +  ERD
Sbjct: 111  GENDDLMGQ-KKALEDL----NK-QLNEDNESMKRT-MGNLEARIDSLSNELSNVERERD 163

Query: 322  SLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQL 381
            +L       L++   ++ E+       E LK +++K  E+L+  +  R  L+++   ++L
Sbjct: 164  AL-------LDENESVKRELERTLTENENLKTELDKADEQLDKLKTERNELQRNFDTMKL 216

Query: 382  EAENLVQRIASKDHELLEKHTEIERLQTLMHG-------EHSNFIQIESALQALQKLYSQ 434
            E E L + + +   +L E   E++ ++ +          + + F +++  +Q L+    +
Sbjct: 217  ENETLKENVKALKDDLEESKREVDEMKAVGDALKDKEELKDAEFRELQQNMQNLKTENGE 276

Query: 435  SQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQ--- 491
             +KE  +L            +LE    + K+E+  +  EN  L     +  + L+K    
Sbjct: 277  LKKENDDLRTR-------SSELEHKLDNVKKELDKVESENADLRAKIDNLEKELEKDKKE 329

Query: 492  ----QMEISKLKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQSL 547
                ++EIS LK+  +K   E      E+  L++E  +++      N   +A   +L+  
Sbjct: 330  IEQLKLEISSLKDALDKCVDEMEKLKVENEKLKKEGMKVEATWLEENVNLKAKNTELE-- 387

Query: 548  GLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDMNEVLMENACMEFSLLGLN 607
                 + A +V +L        +   + +  K+ L    K+++++  E   M+ +L    
Sbjct: 388  ----ENLANTVNELDKMRSENADLLSELNRLKQELESGRKEIDQLKSEIGSMKDALGKCV 443

Query: 608  DELDGLRGTVKEIQQFCQVLQEEKSILADEKSTL---LSQLQ-IITESMQKILENNTV-- 661
            DE++ L+   K+++   Q L+ E+  L +E + L   +S+LQ  +T++ +K+ E  T   
Sbjct: 444  DEIEKLKTENKDLKSEVQGLESERDRLTNEVADLKPKISELQEKLTDASKKLDEAKTEDS 503

Query: 662  --------LEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVEE 713
                    L+K L  A  E + L+ +   L++      +E   L NE S L SQ+  +  
Sbjct: 504  DLRAEVDRLKKELESAGKEIDQLKAEMNSLKNGLNKCVEEMEKLTNENSELKSQVHGLRG 563

Query: 714  KLSNLEKKVTNLEEKYADVEKDKESAVNQV-EELFASILVQKENHSNHKHSSEAR--LAN 770
            +  +L  ++TN++++ + ++ +K+    Q+ E    +  ++K+N      +++ +  L +
Sbjct: 564  EGDSLASELTNVKDENSALKDEKDQLNKQLAENKTENERLKKQNDELESENTKIKKELES 623

Query: 771  LENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQNCIEELELKNFVLLTECEKLVEA 830
             +N    L+EE    K E E+  +++ +   E   L+  ++E E K  +L  +  +    
Sbjct: 624  CKNENNNLKEENNKLKEELEKLGEQLKSLNDETNKLRRELKEAEDKIQILEPQLSRARSE 683

Query: 831  SKFSDKVISEL--ESENLMQLIEEEFL--------LHRIRKFKMDIHKVCGVLQIDSDGG 880
            ++ S   ++ L  E+  L   ++ E L        L  +    +D++K     ++D+   
Sbjct: 684  NEKSQNELAVLRNEANELKVKLDREMLDNTNMRNALKILEDQVLDLNK-----KLDNCRE 738

Query: 881  GDNEIKKEEIPISRIL--------------DKIESLESSLVKSQEENQQLLVENSVLLGS 926
             ++ +K+E   +   L              D ++   +SL K+ E+ +Q + +    +  
Sbjct: 739  ENDALKEENKDLKTKLSDTGQVVLNLKTECDNLKEDIASLQKTIEQLKQKIADQEAEIDH 798

Query: 927  LQ----QHQSEGEKLK--LEK--KTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVN 978
             +    + + + EKLK  LEK  K + +    ++ +   L K+  +L  +  + +  +  
Sbjct: 799  WKVEHCKFELDNEKLKADLEKVLKDLNEYLIKLKNEKDDLNKNMTDLTSQLDRQKRSLEA 858

Query: 979  GVEKENRSKSTLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDE 1038
                ++R    +A+L +E+  L++  +  + +N K   E + L + ++  K+  +   +E
Sbjct: 859  EKSAKDRGDVQIASLNSELEALKKELEKLRADNSKYKSEIDDLGKQLASAKNELNDCREE 918

Query: 1039 -------NSVMFHDVLALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVL 1091
                   NS +  ++  L +L   Y    T    E   L      L      L  EFG L
Sbjct: 919  IVVLKNANSALRSELDPLRSLKDDYSRLTT----ELDGLKSENTKLLQDKRSLEDEFGKL 974

Query: 1092 RKNFEVKEAENVYLNESIERMDKELLEMDKRLKAAETSNAEFSRHIEELKMEQEESTKIK 1151
            R   + +  E   L  +++       ++   L++ +  N +    I E+K   ++     
Sbjct: 975  RGEGDGQRVEIDRLRTTLDAEKTAAEKLKSDLQSCKDENDKLQTQINEMKRSLDKMGTEN 1034

Query: 1152 ENLDRQILEQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLELLNKE 1211
            + L R++ E  +   + + +++ L      L  E + L+ E+  +R RE+  NL      
Sbjct: 1035 DRLKREVDESRKKLEDMEAKVKSLENQLSNLSAEKEELVKEL--YRTREDLNNLR----- 1087

Query: 1212 NEFKLWENEAAAFYHDLQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMREIIS 1271
                          ++L+  +     +E + + L    K L +E +    EN+ ++    
Sbjct: 1088 --------------NELEKQTGVKDTMEKESTNLKEELKALKEELNKTRDENDRLKNEND 1133

Query: 1272 LLESEIGGLKEQLSAYVPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVIETCLRK 1331
             L +EI  L +QL A     ++LK D  +L   +   +K  +V  +         + L+K
Sbjct: 1134 KLNAEIARLNKQLDALKDESANLKNDIENLNERNAELSKELAVAKDNLMGMETRLSNLKK 1193

Query: 1332 HSHQSARENEIVLIPDGVSDLLTLQTRIRAVEKIMMEELKRRVKQ--KSLTTESTPYSSL 1389
             +     +N+I+ + D + +               +++LKR++K+  K L   S    +L
Sbjct: 1194 ENDD--MKNKIITLEDSIQE---------------VDDLKRQLKEAKKELDKPSPELDTL 1236

Query: 1390 EIATYPKVEN-----RKKEIELVEENVFDRNSWRKKPKIRLLMKDIPLDRNVDDQNSKYL 1444
            + +T  K+++     R + + L  +N  D N       ++  + D+  +R+   + +  L
Sbjct: 1237 K-STNKKLQDDLDNARNESLNL--KNDLD-NLQNDYNNLQTELADVKEERDTFRERAAAL 1292

Query: 1445 KREHRRTNDHVLELCENNEHEPLSAPTVDHAMICHRSDDSGRYLNYSSELDIEKELGVDK 1504
            +++  R      EL E N  E L     D    C    ++ R L    +L  E     D 
Sbjct: 1293 EKDLVRVKRENEELVEQN--ETLRTELDD----CR--GENNRLLKELEKLKSENVKLQDN 1344

Query: 1505 LELSKSVKEKTEDDKRRILERLSSDGQKLAILKMALQDLKKKTETKKKSKQGNDIEYETV 1564
            L  ++S  E+ ++D    L +L  D    + L+  L   ++  + +K+     D E + +
Sbjct: 1345 LINARSEGERLKED----LNKLKKD---YSDLRTDLTKAREDRDVRKEKDMELDKEIDEL 1397

Query: 1565 KRHIEEVEEAVMQQVSINDQMAKNVEEGASSLDR 1598
            K    +++  +      N+++ K V +  +  D+
Sbjct: 1398 KAVNAKLKSDLYDCQKENEKLRKQVTKLKAENDK 1431



 Score =  174 bits (441), Expect = 2e-41
 Identities = 230/1214 (18%), Positives = 500/1214 (40%), Gaps = 116/1214 (9%)

Query: 144  SEESNGEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDDRASEA 203
            S++   + + L   L +++ + D L  Q +++LE+L+K   + N++     G        
Sbjct: 92   SKKLKEDNENLWAQLERLRGENDDLMGQ-KKALEDLNKQLNEDNESMKRTMG------NL 144

Query: 204  EIQVEILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIEAKNLKQELTRVVVQ 263
            E +++ L   L  ++ ++DA   L ++       LE  L++ +N     LK EL +   Q
Sbjct: 145  EARIDSLSNELSNVERERDA---LLDENESVKRELERTLTENEN-----LKTELDKADEQ 196

Query: 264  KDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEERDSL 323
             D +  +  +       ++ +    +EN + L D +E ++ EV+ ++     + ++ +  
Sbjct: 197  LDKLKTERNELQRNFDTMKLENETLKENVKALKDDLEESKREVDEMKAVGDALKDKEELK 256

Query: 324  SVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQLEA 383
               +    + +  ++ E   +++  + L+ +  +   KL+  +K    +E  N +L+ + 
Sbjct: 257  DAEFRELQQNMQNLKTENGELKKENDDLRTRSSELEHKLDNVKKELDKVESENADLRAKI 316

Query: 384  ENLVQRIASKDHELLEKHTEIERLQTLMHGEHSNFIQIESALQALQK------------- 430
            +NL + +     E+ +   EI  L+  +        +++   + L+K             
Sbjct: 317  DNLEKELEKDKKEIEQLKLEISSLKDALDKCVDEMEKLKVENEKLKKEGMKVEATWLEEN 376

Query: 431  --LYSQSQKEQRNLAL---ELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSST 485
              L +++ + + NLA    EL        DL       K+E++   +E   L     S  
Sbjct: 377  VNLKAKNTELEENLANTVNELDKMRSENADLLSELNRLKQELESGRKEIDQLKSEIGSMK 436

Query: 486  RSLKKQQMEISKLKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQ 545
             +L K   EI KLK   + L+ E      E + L  E   +K  I  L E+     ++L 
Sbjct: 437  DALGKCVDEIEKLKTENKDLKSEVQGLESERDRLTNEVADLKPKISELQEKLTDASKKLD 496

Query: 546  SLGLNPNSFAASV----RDLQNENFMLKETCKKEHSEKEALREKSKDMNEVLMENACMEF 601
                  +   A V    ++L++    + +   + +S K  L +  ++M ++  EN+ ++ 
Sbjct: 497  EAKTEDSDLRAEVDRLKKELESAGKEIDQLKAEMNSLKNGLNKCVEEMEKLTNENSELKS 556

Query: 602  SLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESMQKILENNTV 661
             + GL  E D L   +  ++     L++EK  L  + +   ++ + + +   ++   NT 
Sbjct: 557  QVHGLRGEGDSLASELTNVKDENSALKDEKDQLNKQLAENKTENERLKKQNDELESENTK 616

Query: 662  LEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVEEKLSNLEKK 721
            ++K L   K E   L+ ++  L++  + L ++  +L +E + L  +L+  E+K+  LE +
Sbjct: 617  IKKELESCKNENNNLKEENNKLKEELEKLGEQLKSLNDETNKLRRELKEAEDKIQILEPQ 676

Query: 722  VTNLEEKYADVEKDKESAVNQVEELFASILVQKENHSNHKHSSEARLANLENIVRVLQEE 781
            ++    +    + +     N+  EL   + + +E   N          N+ N +++L+++
Sbjct: 677  LSRARSENEKSQNELAVLRNEANEL--KVKLDREMLDN---------TNMRNALKILEDQ 725

Query: 782  -----QRLGKVEFEQELDRVVNAQIEMFILQNCIEELELKNFVLLTECEKLVEASKFSDK 836
                 ++L     E +  +  N  ++  +       L LK     TEC+ L E      K
Sbjct: 726  VLDLNKKLDNCREENDALKEENKDLKTKLSDTGQVVLNLK-----TECDNLKEDIASLQK 780

Query: 837  VISELESENLMQLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPISRIL 896
             I +L+ +   Q  E +       KF++D  K+   L+                      
Sbjct: 781  TIEQLKQKIADQEAEIDHWKVEHCKFELDNEKLKADLE---------------------- 818

Query: 897  DKIESLESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQNV 956
              ++ L   L+K + E   L    + L   L + +   E  K  K   + +  ++  +  
Sbjct: 819  KVLKDLNEYLIKLKNEKDDLNKNMTDLTSQLDRQKRSLEAEKSAKDRGDVQIASLNSELE 878

Query: 957  ILQKDKVELLEENRQLRIEVVNGVEKENRSKSTLAALQAEMIELRQTNQVFQEENGKMLD 1016
             L+K+  +L  +N + + E+ +  ++   +K+ L   + E++ L+  N   + E    LD
Sbjct: 879  ALKKELEKLRADNSKYKSEIDDLGKQLASAKNELNDCREEIVVLKNANSALRSE----LD 934

Query: 1017 EKNSLCRNVSDLKDAKSSAEDENSVMFHDVLALSN-----------LNLVYEIFFTENMV 1065
               SL  + S L       + EN+ +  D  +L +             +  +   T    
Sbjct: 935  PLRSLKDDYSRLTTELDGLKSENTKLLQDKRSLEDEFGKLRGEGDGQRVEIDRLRTTLDA 994

Query: 1066 EKRA---LCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIERMDKELLEMDKR 1122
            EK A   L   L +    N+ L  +   ++++ +    EN  L   ++   K+L +M+ +
Sbjct: 995  EKTAAEKLKSDLQSCKDENDKLQTQINEMKRSLDKMGTENDRLKREVDESRKKLEDMEAK 1054

Query: 1123 LKAAETSNAEFSRHIEE--------------LKMEQEESTKIKENLDRQILEQSENCMNH 1168
            +K+ E   +  S   EE              L+ E E+ T +K+ ++++     E     
Sbjct: 1055 VKSLENQLSNLSAEKEELVKELYRTREDLNNLRNELEKQTGVKDTMEKESTNLKEELKAL 1114

Query: 1169 KKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLELLNKENEFKLWENEAAAFYHDL 1228
            K+E+    + N+ L+ E   L  E+ +   + +AL  E  N +N+ +      A    +L
Sbjct: 1115 KEELNKTRDENDRLKNENDKLNAEIARLNKQLDALKDESANLKNDIENLNERNAELSKEL 1174

Query: 1229 QMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMREIISLLESEIGGLKEQLSAYV 1288
             ++   L  +E+++S L    K  +D+   K +  E   + +  L+ ++   K++L    
Sbjct: 1175 AVAKDNLMGMETRLSNL----KKENDDMKNKIITLEDSIQEVDDLKRQLKEAKKELDKPS 1230

Query: 1289 PLVSSLKEDFNSLE 1302
            P + +LK     L+
Sbjct: 1231 PELDTLKSTNKKLQ 1244



 Score =  174 bits (440), Expect = 3e-41
 Identities = 275/1384 (19%), Positives = 591/1384 (41%), Gaps = 179/1384 (12%)

Query: 290  ENSRMLNDQIERTELEVETLRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHVQENAE 349
            E+ R  N ++E    +++ L K L+E+ ++R  L        +++     E+  +Q+   
Sbjct: 17   EDQRAKNKELEACCKDMDALEKKLSELEKKRSELE-------KELEDNRGELERLQKENL 69

Query: 350  QLKNKIEKE-AEKLEISEKHRGMLEKSNQNLQLEAENL---VQRIASKDHELLEKHTEIE 405
             LK+ IE E AEK    +K R +LE+S + L+ + ENL   ++R+  ++ +L+ +   +E
Sbjct: 70   DLKDVIEVERAEK----DKLRDLLEESKK-LKEDNENLWAQLERLRGENDDLMGQKKALE 124

Query: 406  RLQTLMHGEHSNFIQ----IESALQALQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQ 461
             L   ++ ++ +  +    +E+ + +L    S  ++E+  L  E               +
Sbjct: 125  DLNKQLNEDNESMKRTMGNLEARIDSLSNELSNVERERDALLDE--------------NE 170

Query: 462  DFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEISKLKEIKEKLEREFHTSTEESNVLQR 521
              K E++  + EN+ L          L K   ++ KLK  + +L+R F T   E+  L+ 
Sbjct: 171  SVKRELERTLTENENLKT-------ELDKADEQLDKLKTERNELQRNFDTMKLENETLKE 223

Query: 522  ETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEA 581
                +KDD++        M     +L        A  R+LQ     LK    +   E + 
Sbjct: 224  NVKALKDDLEESKREVDEMKAVGDALKDKEELKDAEFRELQQNMQNLKTENGELKKENDD 283

Query: 582  LREKS-----------KDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEE 630
            LR +S           K++++V  ENA +   +  L  EL+  +   KEI+Q    L+ E
Sbjct: 284  LRTRSSELEHKLDNVKKELDKVESENADLRAKIDNLEKELEKDK---KEIEQ----LKLE 336

Query: 631  KSILADEKSTLLSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLL 690
             S L D     + +++ +    +K+ +    +E +  +  +    L+ K+ +LE+     
Sbjct: 337  ISSLKDALDKCVDEMEKLKVENEKLKKEGMKVEATWLEENVN---LKAKNTELEENLANT 393

Query: 691  NDEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASI 750
             +E + +++E + L+S+L  ++++L +  K++  L+ +   ++      V+++E+L    
Sbjct: 394  VNELDKMRSENADLLSELNRLKQELESGRKEIDQLKSEIGSMKDALGKCVDEIEKL---- 449

Query: 751  LVQKENHSNHKHSSEARLANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQNCI 810
              + EN             +L++ V+ L+ E+     E      ++   Q ++      +
Sbjct: 450  --KTENK------------DLKSEVQGLESERDRLTNEVADLKPKISELQEKLTDASKKL 495

Query: 811  EELELKNFVLLTECEKLVEASKFSDKVISELESE------NLMQLIEE-EFLLHRIRKFK 863
            +E + ++  L  E ++L +  + + K I +L++E       L + +EE E L +   + K
Sbjct: 496  DEAKTEDSDLRAEVDRLKKELESAGKEIDQLKAEMNSLKNGLNKCVEEMEKLTNENSELK 555

Query: 864  MDIHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSVL 923
              +H + G  + DS       +K E    S + D+ + L   L +++ EN++L  +N  L
Sbjct: 556  SQVHGLRG--EGDSLASELTNVKDEN---SALKDEKDQLNKQLAENKTENERLKKQNDEL 610

Query: 924  LGSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKE 983
                   +SE  K+K E ++ + E  N++E+N  L+++  +L E+ + L  E      + 
Sbjct: 611  -------ESENTKIKKELESCKNENNNLKEENNKLKEELEKLGEQLKSLNDETNKLRREL 663

Query: 984  NRSKSTLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMF 1043
              ++  +  L+ ++   R  N+  Q E   + +E N L          K   + E     
Sbjct: 664  KEAEDKIQILEPQLSRARSENEKSQNELAVLRNEANEL----------KVKLDRE----- 708

Query: 1044 HDVLALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENV 1103
                 L N N+   +   E+ V    L + L N    N+ L +E   L+          +
Sbjct: 709  ----MLDNTNMRNALKILEDQVLD--LNKKLDNCREENDALKEENKDLKTKLSDTGQVVL 762

Query: 1104 YLNESIERMDKELLEMDKRLKAAETSNAEFSRHIEELKME----QEESTKIKENLDRQIL 1159
             L    + + +++  + K ++  +   A+    I+  K+E    + ++ K+K +L++ + 
Sbjct: 763  NLKTECDNLKEDIASLQKTIEQLKQKIADQEAEIDHWKVEHCKFELDNEKLKADLEKVLK 822

Query: 1160 EQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHR-------VREEALNLELLNKEN 1212
            + +E  +  K E + LN+    L  ++      +E  +       V+  +LN EL   + 
Sbjct: 823  DLNEYLIKLKNEKDDLNKNMTDLTSQLDRQKRSLEAEKSAKDRGDVQIASLNSELEALKK 882

Query: 1213 EFKLWENEAAAFYHDLQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMREI--- 1269
            E +    + + +  ++      LA  ++++++      +L + +SA   E + +R +   
Sbjct: 883  ELEKLRADNSKYKSEIDDLGKQLASAKNELNDCREEIVVLKNANSALRSELDPLRSLKDD 942

Query: 1270 ISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVIETCL 1329
             S L +E+ GLK + +  +    SL+++F  L         R    G   + D +  T  
Sbjct: 943  YSRLTTELDGLKSENTKLLQDKRSLEDEFGKL---------RGEGDGQRVEIDRLRTTLD 993

Query: 1330 RKHSHQSARENEIVLIPDGVSDLLTLQTRIRAVEKIMMEELKRRVKQKSLTTESTPYSSL 1389
             + +     ++++    D    L T            + E+KR + +  + TE+      
Sbjct: 994  AEKTAAEKLKSDLQSCKDENDKLQT-----------QINEMKRSLDK--MGTENDRLKRE 1040

Query: 1390 EIATYPKVENRKKEIELVEENVFDRNSWRKKPKIRLLMKDIPLDRNVDDQNSKYLKREHR 1449
               +  K+E+ + +++ +E  + + ++ +++     L+K+  L R  +D N+   + E +
Sbjct: 1041 VDESRKKLEDMEAKVKSLENQLSNLSAEKEE-----LVKE--LYRTREDLNNLRNELEKQ 1093

Query: 1450 RTNDHVLELCENNEHEPLSAPTVDHAMICHRSDDSGRYLNYSSELDIEKELGVDKLELSK 1509
                  +E    N  E L A   +   +    D++ R  N + +L+ E      +L+  K
Sbjct: 1094 TGVKDTMEKESTNLKEELKALKEE---LNKTRDENDRLKNENDKLNAEIARLNKQLDALK 1150

Query: 1510 SVKEKTEDDKRRILERLSSDGQKLAILKMALQDLKKKTETKKKSKQGNDIEYETVKRHIE 1569
                  ++D   + ER +   ++LA+ K  L  ++ +    KK       +  T++  I+
Sbjct: 1151 DESANLKNDIENLNERNAELSKELAVAKDNLMGMETRLSNLKKENDDMKNKIITLEDSIQ 1210

Query: 1570 EVEEAVMQQVSINDQMAKNVEEGASSLDREIPRRGS--EQIGKLQFEVQNIQYILLKLAE 1627
            EV           D + + ++E    LD+  P   +      KLQ ++ N +   L L  
Sbjct: 1211 EV-----------DDLKRQLKEAKKELDKPSPELDTLKSTNKKLQDDLDNARNESLNLKN 1259

Query: 1628 ENNN 1631
            + +N
Sbjct: 1260 DLDN 1263



 Score =  156 bits (395), Expect = 4e-36
 Identities = 195/944 (20%), Positives = 397/944 (41%), Gaps = 72/944 (7%)

Query: 127  SHTSARPTHRSKK-NERSSEESN--GEVQTLREALAKMQSDKDALFLQYQESLENLSKME 183
            S    + T  SKK +E  +E+S+   EV  L++ L     + D L  +       L+K  
Sbjct: 482  SELQEKLTDASKKLDEAKTEDSDLRAEVDRLKKELESAGKEIDQLKAEMNSLKNGLNKCV 541

Query: 184  TDLNKAQNNARGLDDRASEAEIQVEILKESLMQLKAD----KDAGEVLYNQCLETIARLE 239
             ++ K  N    L  +      + + L   L  +K +    KD  + L  Q  E     E
Sbjct: 542  EEMEKLTNENSELKSQVHGLRGEGDSLASELTNVKDENSALKDEKDQLNKQLAENKTENE 601

Query: 240  SMLSQKDNIEAKNLKQELTRVVVQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQI 299
             +  Q D +E++N K            +  + + C  +   L+ +    +E    L +Q+
Sbjct: 602  RLKKQNDELESENTK------------IKKELESCKNENNNLKEENNKLKEELEKLGEQL 649

Query: 300  ERTELEVETLRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEA 359
            +    E   LR+ L E  ++   L         +  K +NE+  ++  A +LK K+++E 
Sbjct: 650  KSLNDETNKLRRELKEAEDKIQILEPQLSRARSENEKSQNELAVLRNEANELKVKLDREM 709

Query: 360  -------EKLEISEKHRGMLEKSNQNLQLEAENLVQRIASKDHELLEKHTEIERLQTLMH 412
                     L+I E     L K   N + E + L +       +L +    +  L+T   
Sbjct: 710  LDNTNMRNALKILEDQVLDLNKKLDNCREENDALKEENKDLKTKLSDTGQVVLNLKTECD 769

Query: 413  GEHSNFIQIESALQALQKLYSQSQKEQRNLALE-LKYGL---LLLKDLELSKQDFKEEMQ 468
                +   ++  ++ L++  +  + E  +  +E  K+ L    L  DLE   +D  E + 
Sbjct: 770  NLKEDIASLQKTIEQLKQKIADQEAEIDHWKVEHCKFELDNEKLKADLEKVLKDLNEYLI 829

Query: 469  GIVEENKTLHELNFSSTRSLKKQQMEISKLKEIKEKLEREFHTSTEESNVLQRETHQIKD 528
             +  E   L++     T  L +Q+  +   K  K++ + +  +   E   L++E  +++ 
Sbjct: 830  KLKNEKDDLNKNMTDLTSQLDRQKRSLEAEKSAKDRGDVQIASLNSELEALKKELEKLRA 889

Query: 529  DIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKD 588
            D    N +Y++   ++  LG    S    + D + E  +LK       SE + LR    D
Sbjct: 890  D----NSKYKS---EIDDLGKQLASAKNELNDCREEIVVLKNANSALRSELDPLRSLKDD 942

Query: 589  MNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQII 648
             +               L  ELDGL+    ++ Q  + L++E   L  E      ++  +
Sbjct: 943  YSR--------------LTTELDGLKSENTKLLQDKRSLEDEFGKLRGEGDGQRVEIDRL 988

Query: 649  TESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQL 708
              ++         L+  L   K E + L+ +  +++     +  E + L+ E      +L
Sbjct: 989  RTTLDAEKTAAEKLKSDLQSCKDENDKLQTQINEMKRSLDKMGTENDRLKREVDESRKKL 1048

Query: 709  EIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHSNHKHSSEARL 768
            E +E K+ +LE +++NL  +  ++ K+    + +  E   ++  + E  +  K + E   
Sbjct: 1049 EDMEAKVKSLENQLSNLSAEKEELVKE----LYRTREDLNNLRNELEKQTGVKDTMEKES 1104

Query: 769  ANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQNCIEELELKNFVLLTECEKLV 828
             NL+  ++ L+EE    + E ++  +       E+  L   ++ L+ ++  L  + E L 
Sbjct: 1105 TNLKEELKALKEELNKTRDENDRLKNENDKLNAEIARLNKQLDALKDESANLKNDIENLN 1164

Query: 829  EASKFSDKVISELESENLMQLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKE 888
            E +    K ++ +  +NLM +   E  L  ++K   D+     ++ ++      +++K++
Sbjct: 1165 ERNAELSKELA-VAKDNLMGM---ETRLSNLKKENDDMKNK--IITLEDSIQEVDDLKRQ 1218

Query: 889  EIPISRILDK----IESLESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLEKKTV 944
                 + LDK    +++L+S+  K Q++      E+  L   L   Q++   L+ E   V
Sbjct: 1219 LKEAKKELDKPSPELDTLKSTNKKLQDDLDNARNESLNLKNDLDNLQNDYNNLQTELADV 1278

Query: 945  EQEFENMREQNVILQKDKV-------ELLEENRQLRIEVVNGVEKENRSKSTLAALQAEM 997
            ++E +  RE+   L+KD V       EL+E+N  LR E+ +   + NR    L  L++E 
Sbjct: 1279 KEERDTFRERAAALEKDLVRVKRENEELVEQNETLRTELDDCRGENNRLLKELEKLKSEN 1338

Query: 998  IELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSV 1041
            ++L+      + E  ++ ++ N L ++ SDL+   + A ++  V
Sbjct: 1339 VKLQDNLINARSEGERLKEDLNKLKKDYSDLRTDLTKAREDRDV 1382



 Score =  147 bits (371), Expect = 3e-33
 Identities = 252/1147 (21%), Positives = 481/1147 (40%), Gaps = 149/1147 (12%)

Query: 595  ENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESMQK 654
            E A +   L  L +EL+  R   KE++  C      K + A EK   LS+L+     ++K
Sbjct: 1    EQASLSAELEDLRNELEDQRAKNKELEACC------KDMDALEKK--LSELEKKRSELEK 52

Query: 655  ILENN----TVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEI 710
             LE+N      L+K   D K   E  R +   L D    L +E   L+ +   L +QLE 
Sbjct: 53   ELEDNRGELERLQKENLDLKDVIEVERAEKDKLRD----LLEESKKLKEDNENLWAQLER 108

Query: 711  VEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHSNHKHSSEARLAN 770
            +  +  +L  +   LE+    + +D ES    +  L A I       SN +   +A L  
Sbjct: 109  LRGENDDLMGQKKALEDLNKQLNEDNESMKRTMGNLEARIDSLSNELSNVERERDALLDE 168

Query: 771  LENIVRVLQE---EQRLGKVEFEQELDRVVNAQIEMFILQNCIEELELKNFVLLTECEKL 827
             E++ R L+    E    K E ++  +++   + E   LQ   + ++L+N  L    + L
Sbjct: 169  NESVKRELERTLTENENLKTELDKADEQLDKLKTERNELQRNFDTMKLENETLKENVKAL 228

Query: 828  VEASKFSDKVISELESENLMQLIEEEFLLHRIRKFKMDIHKV---CGVLQIDSDG--GGD 882
             +  + S + + E+++       +EE      R+ + ++  +    G L+ ++D      
Sbjct: 229  KDDLEESKREVDEMKAVGDALKDKEELKDAEFRELQQNMQNLKTENGELKKENDDLRTRS 288

Query: 883  NEIKKEEIPISRILDKIES-----------LESSLVKSQEENQQLLVENSVLLGSLQQHQ 931
            +E++ +   + + LDK+ES           LE  L K ++E +QL +E S L  +L +  
Sbjct: 289  SELEHKLDNVKKELDKVESENADLRAKIDNLEKELEKDKKEIEQLKLEISSLKDALDKCV 348

Query: 932  SEGEKLKLEKKTVE-----------QEFENMREQNVILQKDKVELLEENRQLRIEVVNGV 980
             E EKLK+E + ++           +E  N++ +N  L+++    + E  ++R E  + +
Sbjct: 349  DEMEKLKVENEKLKKEGMKVEATWLEENVNLKAKNTELEENLANTVNELDKMRSENADLL 408

Query: 981  EKENRSKSTLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENS 1040
             + NR K  L + + E+ +L+      ++  GK +DE   L     DLK      E E  
Sbjct: 409  SELNRLKQELESGRKEIDQLKSEIGSMKDALGKCVDEIEKLKTENKDLKSEVQGLESERD 468

Query: 1041 VMFHDVLALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEV--K 1098
             + ++V  L           +E   +     + L      ++DL  E   L+K  E   K
Sbjct: 469  RLTNEVADLKPK-------ISELQEKLTDASKKLDEAKTEDSDLRAEVDRLKKELESAGK 521

Query: 1099 EAENVY---------LNESIERMDK------------------------ELLEMDKRLKA 1125
            E + +          LN+ +E M+K                        EL  +     A
Sbjct: 522  EIDQLKAEMNSLKNGLNKCVEEMEKLTNENSELKSQVHGLRGEGDSLASELTNVKDENSA 581

Query: 1126 AETSNAEFSRHIEELKMEQEESTKIKENLDRQ---ILEQSENCMNH-----------KKE 1171
             +    + ++ + E K E E   K  + L+ +   I ++ E+C N            K+E
Sbjct: 582  LKDEKDQLNKQLAENKTENERLKKQNDELESENTKIKKELESCKNENNNLKEENNKLKEE 641

Query: 1172 IEHLNEANETLQFEMKTLLHEVEQHRVREEALNLELLNKENEFKLWENEAAAFYHDLQMS 1231
            +E L E  ++L  E   L  E+++   + + L  +L    +E +  +NE A   ++    
Sbjct: 642  LEKLGEQLKSLNDETNKLRRELKEAEDKIQILEPQLSRARSENEKSQNELAVLRNEANEL 701

Query: 1232 SICLALLESKVSELTGVCKILDDESSAKSLENEHMREIISLLESEIGGLKEQLSAYVPLV 1291
             + L       + +    KIL+D+    + + ++ RE    L+ E   LK +LS    +V
Sbjct: 702  KVKLDREMLDNTNMRNALKILEDQVLDLNKKLDNCREENDALKEENKDLKTKLSDTGQVV 761

Query: 1292 SSLKEDFNSL-EHISLLWTKRNSVVGNGAQKDVVI-----ETCLRKHSHQSARENEIVLI 1345
             +LK + ++L E I+ L      +    A ++  I     E C  +  ++  + +   ++
Sbjct: 762  LNLKTECDNLKEDIASLQKTIEQLKQKIADQEAEIDHWKVEHCKFELDNEKLKADLEKVL 821

Query: 1346 PDGVSDLLTLQTRIRAVEKIMME---ELKRRVKQKSLTTESTPYSSLEIATY-PKVENRK 1401
             D    L+ L+     + K M +   +L R+ +       +     ++IA+   ++E  K
Sbjct: 822  KDLNEYLIKLKNEKDDLNKNMTDLTSQLDRQKRSLEAEKSAKDRGDVQIASLNSELEALK 881

Query: 1402 KEIELVEENVFDRNSWRKKPKIRLLMKDIPLDRN-VDDQNSKYLKREHRRTNDHVLELCE 1460
            KE+E +  +    NS + K +I  L K +   +N ++D   + +  ++  +         
Sbjct: 882  KELEKLRAD----NS-KYKSEIDDLGKQLASAKNELNDCREEIVVLKNANS-------AL 929

Query: 1461 NNEHEPLSAPTVDHAMICHRSDDSGRYLNYSSELDIEKELGVDKLELSKSVKEKTEDDKR 1520
             +E +PL +   D             Y   ++ELD  K      L+  +S+    ED+  
Sbjct: 930  RSELDPLRSLKDD-------------YSRLTTELDGLKSENTKLLQDKRSL----EDEFG 972

Query: 1521 RILERLSSDGQKLAI--LKMALQDLKKKTETKKKSKQGNDIEYETVKRHIEEVEEAVMQQ 1578
            ++  R   DGQ++ I  L+  L   K   E  K   Q    E + ++  I E++ ++ + 
Sbjct: 973  KL--RGEGDGQRVEIDRLRTTLDAEKTAAEKLKSDLQSCKDENDKLQTQINEMKRSLDKM 1030

Query: 1579 VSINDQMAKNVEEGASSL-DREIPRRGSE-QIGKLQFEVQNIQYILLKLAEENNNKVKNR 1636
             + ND++ + V+E    L D E   +  E Q+  L  E + +   L +  E+ NN ++N 
Sbjct: 1031 GTENDRLKREVDESRKKLEDMEAKVKSLENQLSNLSAEKEELVKELYRTREDLNN-LRNE 1089

Query: 1637 ISRKTGI 1643
            + ++TG+
Sbjct: 1090 LEKQTGV 1096



 Score =  116 bits (291), Expect = 5e-24
 Identities = 157/717 (21%), Positives = 303/717 (41%), Gaps = 93/717 (12%)

Query: 93   LRHAHKTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKNERSSEESNGEVQ 152
            L+  +K +     ++   +LN  + C +L  D  S        + K  ++ +E  + +V+
Sbjct: 743  LKEENKDLKTKLSDTGQVVLNLKTECDNLKEDIASLQKTIEQLKQKIADQEAEIDHWKVE 802

Query: 153  TLREAL--AKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDDRASEAEIQVEIL 210
              +  L   K+++D + +     E L  L   + DLNK       + D  S+ + Q    
Sbjct: 803  HCKFELDNEKLKADLEKVLKDLNEYLIKLKNEKDDLNK------NMTDLTSQLDRQ---- 852

Query: 211  KESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIEAKN--LKQELTRVVVQKDTVL 268
            K SL   K+ KD G+V   Q     + LE++  + + + A N   K E+  +  Q  +  
Sbjct: 853  KRSLEAEKSAKDRGDV---QIASLNSELEALKKELEKLRADNSKYKSEIDDLGKQLASAK 909

Query: 269  LQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELE-VETLRKNLAEMNEERDSLSVLY 327
             +   C E+I +L+N       NS +      R+EL+ + +L+ + + +  E D L    
Sbjct: 910  NELNDCREEIVVLKNA------NSAL------RSELDPLRSLKDDYSRLTTELDGLKSEN 957

Query: 328  HHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQLEAENLV 387
               L+    +E+E   ++   +  + +I++    L+  +     L+   Q+ + E + L 
Sbjct: 958  TKLLQDKRSLEDEFGKLRGEGDGQRVEIDRLRTTLDAEKTAAEKLKSDLQSCKDENDKLQ 1017

Query: 388  QRIASKDHELLEKHTEIERLQTLMHGEHSNFIQIESALQALQKLYSQSQKEQRNLALELK 447
             +I      L +  TE +RL+  +         +E+ +++L+   S    E+  L  EL 
Sbjct: 1018 TQINEMKRSLDKMGTENDRLKREVDESRKKLEDMEAKVKSLENQLSNLSAEKEELVKELY 1077

Query: 448  YGLLLLKDL--ELSKQD-----FKEEMQGIVEENKTLHELNFSSTRSLKKQQMEISKLKE 500
                 L +L  EL KQ       ++E   + EE K L E        L K + E  +LK 
Sbjct: 1078 RTREDLNNLRNELEKQTGVKDTMEKESTNLKEELKALKE-------ELNKTRDENDRLKN 1130

Query: 501  IKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRD 560
              +KL  E     ++ + L+ E+  +K+DI++LNER   + ++L     N       + +
Sbjct: 1131 ENDKLNAEIARLNKQLDALKDESANLKNDIENLNERNAELSKELAVAKDNLMGMETRLSN 1190

Query: 561  LQNEN-------FMLKETCKKEHSEKEALREKSKDMNEVLME-------NACMEFSL--- 603
            L+ EN         L+++ ++    K  L+E  K++++   E       N  ++  L   
Sbjct: 1191 LKKENDDMKNKIITLEDSIQEVDDLKRQLKEAKKELDKPSPELDTLKSTNKKLQDDLDNA 1250

Query: 604  ----LGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESMQKILENN 659
                L L ++LD L+     +Q     ++EE+    +  + L   L  +    ++++E N
Sbjct: 1251 RNESLNLKNDLDNLQNDYNNLQTELADVKEERDTFRERAAALEKDLVRVKRENEELVEQN 1310

Query: 660  TVLEKSLSDAK-------IEFEGLRIKSGDLEDCC-------KLLNDEKNNLQNERSMLI 705
              L   L D +        E E L+ ++  L+D         + L ++ N L+ + S L 
Sbjct: 1311 ETLRTELDDCRGENNRLLKELEKLKSENVKLQDNLINARSEGERLKEDLNKLKKDYSDLR 1370

Query: 706  SQL-------EIVEEKLSNLEKKVTNLEEKYA-------DVEKDKESAVNQVEELFA 748
            + L       ++ +EK   L+K++  L+   A       D +K+ E    QV +L A
Sbjct: 1371 TDLTKAREDRDVRKEKDMELDKEIDELKAVNAKLKSDLYDCQKENEKLRKQVTKLKA 1427



 Score = 79.0 bits (193), Expect = 1e-12
 Identities = 86/455 (18%), Positives = 193/455 (41%), Gaps = 33/455 (7%)

Query: 138  KKNERSSEESNGEVQT----LREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNA 193
            K + +S ++ N ++QT    ++ +L KM ++ D L  +  ES + L  ME  +   +N  
Sbjct: 1003 KSDLQSCKDENDKLQTQINEMKRSLDKMGTENDRLKREVDESRKKLEDMEAKVKSLENQL 1062

Query: 194  RGLDDRASEAEIQVEILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNI--EAK 251
              L     E   ++   +E L  L+          N+  +     ++M  +  N+  E K
Sbjct: 1063 SNLSAEKEELVKELYRTREDLNNLR----------NELEKQTGVKDTMEKESTNLKEELK 1112

Query: 252  NLKQELTRVVVQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRK 311
             LK+EL +   + D +  +  +   +I  L  ++   ++ S  L + IE        L K
Sbjct: 1113 ALKEELNKTRDENDRLKNENDKLNAEIARLNKQLDALKDESANLKNDIENLNERNAELSK 1172

Query: 312  NLAEMNEERDSLSVLYHHCLEKISKMENEILHVQENAEQ---LKNKIEKEAEKLEISEKH 368
             LA   +    +     +  ++   M+N+I+ ++++ ++   LK ++++  ++L+     
Sbjct: 1173 ELAVAKDNLMGMETRLSNLKKENDDMKNKIITLEDSIQEVDDLKRQLKEAKKELDKPSPE 1232

Query: 369  RGMLEKSNQNLQLEAENLVQRIASKDHELLEKHTEIERLQTLMHGEHSNFIQIESALQAL 428
               L+ +N+ LQ + +N      +  ++L     +   LQT +               AL
Sbjct: 1233 LDTLKSTNKKLQDDLDNARNESLNLKNDLDNLQNDYNNLQTELADVKEERDTFRERAAAL 1292

Query: 429  QKLYSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSL 488
            +K   + ++E   L  + +     L D         +E++ +  EN  L +   ++    
Sbjct: 1293 EKDLVRVKRENEELVEQNETLRTELDDCRGENNRLLKELEKLKSENVKLQDNLINARSEG 1352

Query: 489  KKQQMEISKLKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQSLG 548
            ++ + +++KLK+    L  +   + E+ +V + +  ++  +I  L    +A+  +L+S  
Sbjct: 1353 ERLKEDLNKLKKDYSDLRTDLTKAREDRDVRKEKDMELDKEIDEL----KAVNAKLKS-- 1406

Query: 549  LNPNSFAASVRDLQNENFMLKETCKKEHSEKEALR 583
                     + D Q EN  L++   K  +E + L+
Sbjct: 1407 --------DLYDCQKENEKLRKQVTKLKAENDKLK 1433


>UniRef100_UPI000043298D UPI000043298D UniRef100 entry
          Length = 1327

 Score =  182 bits (462), Expect = 8e-44
 Identities = 269/1294 (20%), Positives = 551/1294 (41%), Gaps = 145/1294 (11%)

Query: 65   RPELMKLVEEFYRAYRALAERYDHAMGELRHAHKTMPEAFPNSAYYILNDDSPCGSLGPD 124
            + +L  L  E Y     L E  +  M EL     T+ E   +    IL D +        
Sbjct: 23   KSKLEHLEPELYE----LRESKEEIMEELNMMRDTLKER-NDQIIQILEDKAKL------ 71

Query: 125  AESHTSARPTHRSKKNERSS-----EESNGEVQTLREALAKMQS---DKDALFLQYQESL 176
             E + S   T  +K +E++S     E+   E++  R    ++++   D DAL    ++ L
Sbjct: 72   EEYYKSKVETLEAKLDEQASLSAELEDLRNELEDQRAKNKELEACCKDMDAL----EKKL 127

Query: 177  ENLSKMETDLNKAQNNARGLDDRASEAEIQVEILKESLMQLKADKDAGEVLYNQCLETIA 236
              L K  ++L K   + RG  +R  +  +    LK+ +   +A+KD    L         
Sbjct: 128  SELEKKRSELEKELEDNRGELERLQKENLD---LKDVIEVERAEKDKLRDLLE------- 177

Query: 237  RLESMLSQKDNIEAKNLKQELTRVVVQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLN 296
              ES   ++DN   +NL  +L R+  + D ++ Q K+ LE +    NK  L E+N  M  
Sbjct: 178  --ESKKLKEDN---ENLWAQLERLRGENDDLMGQ-KKALEDL----NK-QLNEDNESMKR 226

Query: 297  DQIERTELEVETLRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIE 356
              +   E  +++L   L+ +  ERD+L       L++   ++ E+       E LK +++
Sbjct: 227  T-MGNLEARIDSLSNELSNVERERDAL-------LDENESVKRELERTLTENENLKTELD 278

Query: 357  KEAEKLEISEKHRGMLEKSNQNLQLEAENLVQRIASKDHELLEKHTEIERLQTLMHG--- 413
            K  E+L+  +  R  L+++   ++LE E L + + +   +L E   E++ ++ +      
Sbjct: 279  KADEQLDKLKTERNELQRNFDTMKLENETLKENVKALKDDLEESKREVDEMKAVGDALKD 338

Query: 414  ----EHSNFIQIESALQALQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQG 469
                + + F +++  +Q L+    + +KE  +L            +LE    + K+E+  
Sbjct: 339  KEELKDAEFRELQQNMQNLKTENGELKKENDDLRTR-------SSELEHKLDNVKKELDK 391

Query: 470  IVEENKTLHELNFSSTRSLKKQ-------QMEISKLKEIKEKLEREFHTSTEESNVLQRE 522
            +  EN  L     +  + L+K        ++EIS LK+  +K   E      E+  L++E
Sbjct: 392  VESENADLRAKIDNLEKELEKDKKEIEQLKLEISSLKDALDKCVDEMEKLKVENEKLKKE 451

Query: 523  THQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEAL 582
              +++      N   +A   +L+       + A +V +L        +   + +  K+ L
Sbjct: 452  GMKVEATWLEENVNLKAKNTELE------ENLANTVNELDKMRSENADLLSELNRLKQEL 505

Query: 583  REKSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTL- 641
                K+++++  E   M+ +L    DE++ L+   K+++   Q L+ E+  L +E + L 
Sbjct: 506  ESGRKEIDQLKSEIGSMKDALGKCVDEIEKLKTENKDLKSEVQGLESERDRLTNEVADLK 565

Query: 642  --LSQLQ-IITESMQKILENNTV----------LEKSLSDAKIEFEGLRIKSGDLEDCCK 688
              +S+LQ  +T++ +K+ E  T           L+K L  A  E + L+ +   L++   
Sbjct: 566  PKISELQEKLTDASKKLDEAKTEDSDLRAEVDRLKKELESAGKEIDQLKAEMNSLKNGLN 625

Query: 689  LLNDEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQV-EELF 747
               +E   L NE S L SQ+  +  +  +L  ++TN++++ + ++ +K+    Q+ E   
Sbjct: 626  KCVEEMEKLTNENSELKSQVHGLRGEGDSLASELTNVKDENSALKDEKDQLNKQLAENKT 685

Query: 748  ASILVQKENHSNHKHSSEAR--LANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFI 805
             +  ++K+N      +++ +  L + +N    L+EE    K E E+  +++ +   E   
Sbjct: 686  ENERLKKQNDELESENTKIKKELESCKNENNNLKEENNKLKEELEKLGEQLKSLNDETNK 745

Query: 806  LQNCIEELELKNFVLLTECEKLVEASKFSDKVISELESENLMQLIEEEFLLHRIRKFKMD 865
            L+  ++E E K  +L              +  +S   SEN     E   L +   + K+ 
Sbjct: 746  LRRELKEAEDKIQIL--------------EPQLSRARSENEKSQNELAVLRNEANELKVK 791

Query: 866  IHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSVLLG 925
            + +             DN   +  + I  + D++  L   L   +EEN  L  EN  L  
Sbjct: 792  LDREM----------LDNTNMRNALKI--LEDQVLDLNKKLDNCREENDALKEENKDLKT 839

Query: 926  SLQQHQSEGEKLKLEKKTVEQEFEN---MREQNVILQKDKVELLEENRQLRIEVVNGVEK 982
             L         LK E   ++++  N   ++ +   L K+  +L  +  + +  +      
Sbjct: 840  KLSDTGQVVLNLKTECDNLKEDIANLIKLKNEKDDLNKNMTDLTSQLDRQKRSLEAEKSA 899

Query: 983  ENRSKSTLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVM 1042
            ++R    +A+L +E+  L++  +  + +N K   E + L + ++  K+  +   +E  V 
Sbjct: 900  KDRGDVQIASLNSELEALKKELEKLRADNSKYKSEIDDLGKQLASAKNELNDCREEIVVG 959

Query: 1043 FHDVLALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAEN 1102
              D   +    L   +   +   EK  L   L +    N+ L  +   ++++ +    EN
Sbjct: 960  EGDGQRVEIDRLRTTLDAEKTAAEK--LKSDLQSCKDENDKLQTQINEMKRSLDKMGTEN 1017

Query: 1103 VYLNESIERMDKELLEMDKRLKAAETSNAEFSRHIEE--------------LKMEQEEST 1148
              L   ++   K+L +M+ ++K+ E   +  S   EE              L+ E E+ T
Sbjct: 1018 DRLKREVDESRKKLEDMEAKVKSLENQLSNLSAEKEELVKELYRTREDLNNLRNELEKQT 1077

Query: 1149 KIKENLDRQILEQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLELL 1208
             +K+ ++++     E     K+E+    + N+ L+ E   L  E+ +   + +AL  E  
Sbjct: 1078 GVKDTMEKESTNLKEELKALKEELNKTRDENDRLKNENDKLNAEIARLNKQLDALKDESA 1137

Query: 1209 NKENEFKLWENEAAAFYHDLQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMRE 1268
            N +N+ +      A    +L ++   L  +E+++S L    K  +D+   K +  E   +
Sbjct: 1138 NLKNDIENLNERNAELSKELAVAKDNLMGMETRLSNL----KKENDDMKNKIITLEDSIQ 1193

Query: 1269 IISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLE 1302
             +  L+ ++   K++L    P + +LK     L+
Sbjct: 1194 EVDDLKRQLKEAKKELDKPSPELDTLKSTNKKLQ 1227



 Score =  172 bits (437), Expect = 6e-41
 Identities = 306/1427 (21%), Positives = 579/1427 (40%), Gaps = 175/1427 (12%)

Query: 256  ELTRVVVQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAE 315
            +L   + Q +  LL  +    K+  LE ++    E+   + +++      ++     + +
Sbjct: 4    DLLNTLRQSEINLLGLEGLKSKLEHLEPELYELRESKEEIMEELNMMRDTLKERNDQIIQ 63

Query: 316  MNEERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEK---LEISEKHRGML 372
            + E++  L   Y   +E +    +E   +    E L+N++E +  K   LE   K    L
Sbjct: 64   ILEDKAKLEEYYKSKVETLEAKLDEQASLSAELEDLRNELEDQRAKNKELEACCKDMDAL 123

Query: 373  EKSNQNLQLEAENLVQRIASKDHELLEKHTEIERLQTLMHGEHSNFIQIESALQ-ALQKL 431
            EK    L+ +   L       + EL +   E+ERLQ   + +  + I++E A +  L+ L
Sbjct: 124  EKKLSELEKKRSEL-------EKELEDNRGELERLQK-ENLDLKDVIEVERAEKDKLRDL 175

Query: 432  YSQSQK---EQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSL 488
              +S+K   +  NL  +L+        L     D   + + + + NK L+E N S  R++
Sbjct: 176  LEESKKLKEDNENLWAQLER-------LRGENDDLMGQKKALEDLNKQLNEDNESMKRTM 228

Query: 489  KKQQMEISKLKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQSLG 548
               +  I  L      +ERE     +E+  ++RE  +   + ++L        EQL  L 
Sbjct: 229  GNLEARIDSLSNELSNVERERDALLDENESVKRELERTLTENENLKTELDKADEQLDKLK 288

Query: 549  LNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDMNEVLMENACMEFSLLGLND 608
               N    +   ++ EN  LKE  K   + K+ L E  ++++E+      ++      + 
Sbjct: 289  TERNELQRNFDTMKLENETLKENVK---ALKDDLEESKREVDEMKAVGDALKDKEELKDA 345

Query: 609  ELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESMQKILENNTVL------ 662
            E   L+  ++ ++     L++E   L    S L  +L  + + + K+   N  L      
Sbjct: 346  EFRELQQNMQNLKTENGELKKENDDLRTRSSELEHKLDNVKKELDKVESENADLRAKIDN 405

Query: 663  -EKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVE----EKLSN 717
             EK L   K E E L+++   L+D      DE   L+ E   L  +   VE    E+  N
Sbjct: 406  LEKELEKDKKEIEQLKLEISSLKDALDKCVDEMEKLKVENEKLKKEGMKVEATWLEENVN 465

Query: 718  LEKKVTNLEEKYADVEKDKESAVNQVEELFASI-LVQKENHSNHKHSSEAR--------- 767
            L+ K T LEE  A+   + +   ++  +L + +  +++E  S  K   + +         
Sbjct: 466  LKAKNTELEENLANTVNELDKMRSENADLLSELNRLKQELESGRKEIDQLKSEIGSMKDA 525

Query: 768  LANLENIVRVLQEEQRLGKVE---FEQELDRVVNAQIEMFILQNCIEELELKNFVLLTEC 824
            L    + +  L+ E +  K E    E E DR+ N   E+  L+  I EL+ K    LT+ 
Sbjct: 526  LGKCVDEIEKLKTENKDLKSEVQGLESERDRLTN---EVADLKPKISELQEK----LTDA 578

Query: 825  EKLVEASKFSDKVISELESENLMQLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNE 884
             K ++ +K  D   S+L +E           + R++K            +++S G   ++
Sbjct: 579  SKKLDEAKTED---SDLRAE-----------VDRLKK------------ELESAGKEIDQ 612

Query: 885  IKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLEKKTV 944
            +K E          + SL++ L K  EE ++L  ENS L   +   + EG+ L  E   V
Sbjct: 613  LKAE----------MNSLKNGLNKCVEEMEKLTNENSELKSQVHGLRGEGDSLASELTNV 662

Query: 945  EQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKENRSKSTLAALQAEMIELRQTN 1004
            + E   ++++   L K   E   EN +L+ +      +  + K  L + + E   L++ N
Sbjct: 663  KDENSALKDEKDQLNKQLAENKTENERLKKQNDELESENTKIKKELESCKNENNNLKEEN 722

Query: 1005 QVFQEENGK-------MLDEKNSLCRNVSDLKD-------AKSSAEDENSVMFHDVLALS 1050
               +EE  K       + DE N L R + + +D         S A  EN    +++  L 
Sbjct: 723  NKLKEELEKLGEQLKSLNDETNKLRRELKEAEDKIQILEPQLSRARSENEKSQNELAVLR 782

Query: 1051 NLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIE 1110
            N     ++     M++   +   L  L     DLN++    R+  +  + EN  L   + 
Sbjct: 783  NEANELKVKLDREMLDNTNMRNALKILEDQVLDLNKKLDNCREENDALKEENKDLKTKLS 842

Query: 1111 RMDKELLEMDKRLKAAETSNAEFSRHIEELKMEQEESTKIKENLDRQILEQSENCMNHKK 1170
               + +L     LK    +  E   ++ +LK E+++  K   +L  Q+  Q  +    K 
Sbjct: 843  DTGQVVL----NLKTECDNLKEDIANLIKLKNEKDDLNKNMTDLTSQLDRQKRSLEAEKS 898

Query: 1171 -------EIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLELLNKENEFKLWENEAAA 1223
                   +I  LN   E L+ E++ L  +  +++   + L  +L + +NE      E   
Sbjct: 899  AKDRGDVQIASLNSELEALKKELEKLRADNSKYKSEIDDLGKQLASAKNELNDCREEIVV 958

Query: 1224 FYHDLQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMREIISLLESEIGGLKEQ 1283
               D Q   I   L  +  +E T   K+  D  S K  EN+ ++  I+ ++  +  +  +
Sbjct: 959  GEGDGQRVEID-RLRTTLDAEKTAAEKLKSDLQSCKD-ENDKLQTQINEMKRSLDKMGTE 1016

Query: 1284 LSAYVPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVIETCLRKHSHQSARENEIV 1343
                   V   ++    +E  + + +  N +    A+K+ +++   R     +   NE+ 
Sbjct: 1017 NDRLKREVDESRKKLEDME--AKVKSLENQLSNLSAEKEELVKELYRTREDLNNLRNELE 1074

Query: 1344 LIPDGVSDLLTLQ-TRIRAVEKIMMEELKRRVKQKSLTTESTPYSSLEIATYPK----VE 1398
                GV D +  + T ++   K + EEL +   +           + EIA   K    ++
Sbjct: 1075 K-QTGVKDTMEKESTNLKEELKALKEELNKTRDENDRLKNENDKLNAEIARLNKQLDALK 1133

Query: 1399 NRKKEIELVEENVFDRNSWRKKPKIRLLMKDIPLDRNVDDQNSKYLKREHRRTNDHVLEL 1458
            +    ++   EN+ +RN+  +  K   + KD  +       N   LK+E+    + ++ L
Sbjct: 1134 DESANLKNDIENLNERNA--ELSKELAVAKDNLMGMETRLSN---LKKENDDMKNKIITL 1188

Query: 1459 CENNEHEPLSAPTVDHAMICHRSDDSGRYLNYSSELDIEKELGVDKLELS--KSVKEKTE 1516
             ++                    DD  R L      + +KEL     EL   KS  +K +
Sbjct: 1189 EDS----------------IQEVDDLKRQLK-----EAKKELDKPSPELDTLKSTNKKLQ 1227

Query: 1517 DD----------KRRILERLSSDGQKLAILKMALQDLKKKTETKKKSKQGNDIEYETVKR 1566
            DD           +  L+ L +D      L+  L D+K++ +T ++     + +   VKR
Sbjct: 1228 DDLDNARNESLNLKNDLDNLQNDYNN---LQTELADVKEERDTFRERAAALEKDLVRVKR 1284

Query: 1567 HIEE-VEEAVMQQVSINDQMAKNVEEGASSLDREIPRRGSEQIGKLQ 1612
              EE VE+    +  ++D   +N     + L +E+ +  SE + KLQ
Sbjct: 1285 ENEELVEQNETLRTELDDCRGEN-----NRLLKELEKLKSENV-KLQ 1325



 Score =  171 bits (434), Expect = 1e-40
 Identities = 232/1177 (19%), Positives = 504/1177 (42%), Gaps = 161/1177 (13%)

Query: 144  SEESNGEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDDRASEA 203
            S++   + + L   L +++ + D L  Q +++LE+L+K   + N++     G        
Sbjct: 179  SKKLKEDNENLWAQLERLRGENDDLMGQ-KKALEDLNKQLNEDNESMKRTMG------NL 231

Query: 204  EIQVEILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIEAKNLKQELTRVVVQ 263
            E +++ L   L  ++ ++DA   L ++       LE  L++ +N     LK EL +   Q
Sbjct: 232  EARIDSLSNELSNVERERDA---LLDENESVKRELERTLTENEN-----LKTELDKADEQ 283

Query: 264  KDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLR------------- 310
             D +  +  +       ++ +    +EN + L D +E ++ EV+ ++             
Sbjct: 284  LDKLKTERNELQRNFDTMKLENETLKENVKALKDDLEESKREVDEMKAVGDALKDKEELK 343

Query: 311  -----------KNL----AEMNEERDSL----SVLYH---HCLEKISKMENEILHVQENA 348
                       +NL     E+ +E D L    S L H   +  +++ K+E+E   ++   
Sbjct: 344  DAEFRELQQNMQNLKTENGELKKENDDLRTRSSELEHKLDNVKKELDKVESENADLRAKI 403

Query: 349  EQLKNKIEKEAE-----KLEISEKHRGM---------LEKSNQNLQLEAENLVQRIASKD 394
            + L+ ++EK+ +     KLEIS     +         L+  N+ L+ E   +      ++
Sbjct: 404  DNLEKELEKDKKEIEQLKLEISSLKDALDKCVDEMEKLKVENEKLKKEGMKVEATWLEEN 463

Query: 395  HELLEKHTEIER--LQTL-----MHGEHSNFI----QIESALQALQKLYSQSQKEQRNLA 443
              L  K+TE+E     T+     M  E+++ +    +++  L++ +K   Q + E  ++ 
Sbjct: 464  VNLKAKNTELEENLANTVNELDKMRSENADLLSELNRLKQELESGRKEIDQLKSEIGSMK 523

Query: 444  LELKYGLLLLKDLELSKQDFKEEMQGIVEEN--------------KTLHELNFSSTRSLK 489
              L   +  ++ L+   +D K E+QG+  E                 L E    +++ L 
Sbjct: 524  DALGKCVDEIEKLKTENKDLKSEVQGLESERDRLTNEVADLKPKISELQEKLTDASKKLD 583

Query: 490  KQQMEISKLKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQSLGL 549
            + + E S L+   ++L++E  ++ +E + L+ E + +K+ +          +E+++ L  
Sbjct: 584  EAKTEDSDLRAEVDRLKKELESAGKEIDQLKAEMNSLKNGL-------NKCVEEMEKLTN 636

Query: 550  NPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDMNEVLMENACMEFSLLGLNDE 609
              +   + V  L+ E   L         E  AL+++   +N+ L EN      L   NDE
Sbjct: 637  ENSELKSQVHGLRGEGDSLASELTNVKDENSALKDEKDQLNKQLAENKTENERLKKQNDE 696

Query: 610  LDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESMQKILENNTVLEKSLSDA 669
            L+     +K+  + C   + E + L +E + L  +L+ + E ++ + +    L + L +A
Sbjct: 697  LESENTKIKKELESC---KNENNNLKEENNKLKEELEKLGEQLKSLNDETNKLRRELKEA 753

Query: 670  KIEFEGL-------RIKSGDLEDCCKLLNDEKNNL--QNERSML-----ISQLEIVEEKL 715
            + + + L       R ++   ++   +L +E N L  + +R ML      + L+I+E+++
Sbjct: 754  EDKIQILEPQLSRARSENEKSQNELAVLRNEANELKVKLDREMLDNTNMRNALKILEDQV 813

Query: 716  SNLEKKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHSNHKHSSEARLANLENIV 775
             +L KK+ N  E+   ++++ +    ++ +    +L  K    N K        ++ N++
Sbjct: 814  LDLNKKLDNCREENDALKEENKDLKTKLSDTGQVVLNLKTECDNLKE-------DIANLI 866

Query: 776  RVLQEEQRLGK--VEFEQELDRVVNAQIEMFILQNCIEELELKNFVLLTECEKLVEASKF 833
            ++  E+  L K   +   +LDR   +           +  + +  V +      +EA K 
Sbjct: 867  KLKNEKDDLNKNMTDLTSQLDRQKRS-------LEAEKSAKDRGDVQIASLNSELEALK- 918

Query: 834  SDKVISELESENLMQLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPIS 893
              K + +L ++N     E + L  ++   K +++     + +    G   EI +    + 
Sbjct: 919  --KELEKLRADNSKYKSEIDDLGKQLASAKNELNDCREEIVVGEGDGQRVEIDRLRTTLD 976

Query: 894  RILDKIESLESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMRE 953
                  E L+S L   ++EN +L  + + +  SL +  +E ++LK E     ++ E+M  
Sbjct: 977  AEKTAAEKLKSDLQSCKDENDKLQTQINEMKRSLDKMGTENDRLKREVDESRKKLEDMEA 1036

Query: 954  QNVILQKDKVELLEENRQLRIEVVNGVEKENRSKSTLAALQAEMIELRQTNQVFQEENGK 1013
            +   L+     L  E  +L       V++  R++  L  L+ E+ +        ++E+  
Sbjct: 1037 KVKSLENQLSNLSAEKEEL-------VKELYRTREDLNNLRNELEKQTGVKDTMEKESTN 1089

Query: 1014 MLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVLALS-NLNLVYEIFFTENMVEKRALCE 1072
            + +E  +L   ++  +D     ++EN  +  ++  L+  L+ + +        E   L  
Sbjct: 1090 LKEELKALKEELNKTRDENDRLKNENDKLNAEIARLNKQLDALKD--------ESANLKN 1141

Query: 1073 HLGNLSHLNNDLNQEFGVLRKNFEVKEA-------ENVYLNESIERMDKELLEMDKRLKA 1125
             + NL+  N +L++E  V + N    E        EN  +   I  ++  + E+D   + 
Sbjct: 1142 DIENLNERNAELSKELAVAKDNLMGMETRLSNLKKENDDMKNKIITLEDSIQEVDDLKRQ 1201

Query: 1126 AETSNAEFSRHIEELKMEQEESTKIKENLDRQILEQSENCMNHKKEIEHLNEANETLQFE 1185
             + +  E  +   EL   +  + K++++LD    E     +N K ++++L      LQ E
Sbjct: 1202 LKEAKKELDKPSPELDTLKSTNKKLQDDLDNARNES----LNLKNDLDNLQNDYNNLQTE 1257

Query: 1186 MKTLLHEVEQHRVREEALNLEL--LNKENEFKLWENE 1220
            +  +  E +  R R  AL  +L  + +ENE  + +NE
Sbjct: 1258 LADVKEERDTFRERAAALEKDLVRVKRENEELVEQNE 1294



 Score = 79.3 bits (194), Expect = 9e-13
 Identities = 93/475 (19%), Positives = 199/475 (41%), Gaps = 65/475 (13%)

Query: 136  RSKKNERSSEES--------NGEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLN 187
            RS + E+S+++         N E++ L++ L K+++D      +Y+  +++L K      
Sbjct: 891  RSLEAEKSAKDRGDVQIASLNSELEALKKELEKLRADNS----KYKSEIDDLGKQLASAK 946

Query: 188  KAQNNARG--LDDRASEAEIQVEILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQK 245
               N+ R   +        ++++ L+ +L    A+K A E L +        L+S   + 
Sbjct: 947  NELNDCREEIVVGEGDGQRVEIDRLRTTL---DAEKTAAEKLKSD-------LQSCKDEN 996

Query: 246  DNIEAK--NLKQELTRVVVQKDTVLLQYKQCLEK-------IPMLENKIALAEENSRMLN 296
            D ++ +   +K+ L ++  + D +  +  +  +K       +  LEN+++        L 
Sbjct: 997  DKLQTQINEMKRSLDKMGTENDRLKREVDESRKKLEDMEAKVKSLENQLSNLSAEKEELV 1056

Query: 297  DQIERTELEVETLRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIE 356
             ++ RT  ++  LR  L +    +D++     +  E++  ++ E+   ++  ++LKN+ +
Sbjct: 1057 KELYRTREDLNNLRNELEKQTGVKDTMEKESTNLKEELKALKEELNKTRDENDRLKNEND 1116

Query: 357  KEAEKLEISEKHRGMLEKSNQNLQLEAENLVQRIASKDHELLEKHTEIERLQTLMHGEHS 416
            K   ++    K    L+  + NL+ + ENL +R A    EL                   
Sbjct: 1117 KLNAEIARLNKQLDALKDESANLKNDIENLNERNAELSKELAVAK--------------D 1162

Query: 417  NFIQIESALQALQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKT 476
            N + +E+ L  L+K       + +N  + L+  +  + DL+   ++ K+E+     E  T
Sbjct: 1163 NLMGMETRLSNLKK----ENDDMKNKIITLEDSIQEVDDLKRQLKEAKKELDKPSPELDT 1218

Query: 477  LHELNFSSTRSLKKQQMEISKLKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNER 536
            L   N       KK Q ++   +     L+ +      + N LQ E   +K++     ER
Sbjct: 1219 LKSTN-------KKLQDDLDNARNESLNLKNDLDNLQNDYNNLQTELADVKEERDTFRER 1271

Query: 537  YQAMLEQL-------QSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALRE 584
              A+ + L       + L     +    + D + EN  L +  +K  SE   L++
Sbjct: 1272 AAALEKDLVRVKRENEELVEQNETLRTELDDCRGENNRLLKELEKLKSENVKLQD 1326



 Score = 72.4 bits (176), Expect = 1e-10
 Identities = 155/748 (20%), Positives = 293/748 (38%), Gaps = 104/748 (13%)

Query: 904  SSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKV 963
            S L+ +  +++  L+    L   L+  + E  +L+  K+ + +E   MR+         +
Sbjct: 3    SDLLNTLRQSEINLLGLEGLKSKLEHLEPELYELRESKEEIMEELNMMRDTLKERNDQII 62

Query: 964  ELLEENRQLRIEVVNGVEKENRSKSTLAALQAEMIELRQTNQVFQEENGKM---LDEKNS 1020
            ++LE+  +L     + VE         A+L AE+ +LR   +  + +N ++     + ++
Sbjct: 63   QILEDKAKLEEYYKSKVETLEAKLDEQASLSAELEDLRNELEDQRAKNKELEACCKDMDA 122

Query: 1021 LCRNVSDLKDAKSSAEDENSVMFHDVLALSNLNLVYEIFFTENMVEKRALCEHLGNLSHL 1080
            L + +S+L+  +S  E E      ++  L   NL  +        EK  L + L     L
Sbjct: 123  LEKKLSELEKKRSELEKELEDNRGELERLQKENLDLKDVIEVERAEKDKLRDLLEESKKL 182

Query: 1081 NND----------LNQEFGVLRKNFEVKEAENVYLNESIERMDKELLEMDKRLKAAETSN 1130
              D          L  E   L    +  E  N  LNE  E M + +  ++ R+ +     
Sbjct: 183  KEDNENLWAQLERLRGENDDLMGQKKALEDLNKQLNEDNESMKRTMGNLEARIDSLSNEL 242

Query: 1131 AEFSRHIEELKMEQEESTKIKENLDRQILEQSENCMNHKKEIEHLNEANETLQFEMKTLL 1190
            +   R  + L    +E+  +K  L+R + E      N K E++  +E  + L+ E   L 
Sbjct: 243  SNVERERDAL---LDENESVKRELERTLTENE----NLKTELDKADEQLDKLKTERNELQ 295

Query: 1191 HEVEQHRVREEALNLELLNKENEFKLWENEAAAFYHDLQMSSICLALLESKVSELTGVCK 1250
               +  ++  E L      KEN          A   DL+ S       + +V E+  V  
Sbjct: 296  RNFDTMKLENETL------KEN--------VKALKDDLEES-------KREVDEMKAVGD 334

Query: 1251 ILDDESSAKSLENEHMREIISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLEH-ISLLWT 1309
             L D+   K  E   +++ +  L++E G LK++          L+   + LEH +  +  
Sbjct: 335  ALKDKEELKDAEFRELQQNMQNLKTENGELKKE-------NDDLRTRSSELEHKLDNVKK 387

Query: 1310 KRNSVVGNGAQKDVVIETCLRKHSHQSARENEIVLIPDGVSDLLTLQTRIRAVEKIMMEE 1369
            + + V    A     I+  L K   +  +E E +         L + +   A++K + E 
Sbjct: 388  ELDKVESENADLRAKIDN-LEKELEKDKKEIEQL--------KLEISSLKDALDKCVDEM 438

Query: 1370 LKRRVKQKSLTTESTPYSSLEIATYPKVENRKKEIELVEENVFDRNSWRKKPKIRLLMKD 1429
             K +V+ + L                K E  K E   +EENV             L  K+
Sbjct: 439  EKLKVENEKL----------------KKEGMKVEATWLEENV------------NLKAKN 470

Query: 1430 IPLDRNVDDQNSKYLKREHRRTNDHVLELCENNEHEPLSAPTVDH--AMICHRSDDSGRY 1487
              L+ N+ +  ++ L +      D + EL    +        +D   + I    D  G+ 
Sbjct: 471  TELEENLANTVNE-LDKMRSENADLLSELNRLKQELESGRKEIDQLKSEIGSMKDALGKC 529

Query: 1488 LNYSSELDIE-KELGVDKLELSKSVKEKTEDDKRRILERLSSDGQKLAILKMALQDLKKK 1546
            ++   +L  E K+L        KS  +  E ++ R+   ++    K++ L+  L D  KK
Sbjct: 530  VDEIEKLKTENKDL--------KSEVQGLESERDRLTNEVADLKPKISELQEKLTDASKK 581

Query: 1547 TETKKKSKQGNDIEYETVKRHIE----EVEEAVMQQVSINDQMAKNVEEGASSLDREIPR 1602
             +  K        E + +K+ +E    E+++   +  S+ + + K VEE    L  E   
Sbjct: 582  LDEAKTEDSDLRAEVDRLKKELESAGKEIDQLKAEMNSLKNGLNKCVEE-MEKLTNENSE 640

Query: 1603 RGSEQIGKLQFEVQNIQYILLKLAEENN 1630
              S Q+  L+ E  ++   L  + +EN+
Sbjct: 641  LKS-QVHGLRGEGDSLASELTNVKDENS 667



 Score = 41.6 bits (96), Expect = 0.21
 Identities = 96/508 (18%), Positives = 197/508 (37%), Gaps = 72/508 (14%)

Query: 1137 IEELKMEQEESTKIKENLDRQILEQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQH 1196
            +E L+ E  E  + KE +  ++    +       +I  + E    L+   K+ +  +E  
Sbjct: 26   LEHLEPELYELRESKEEIMEELNMMRDTLKERNDQIIQILEDKAKLEEYYKSKVETLEAK 85

Query: 1197 RVREEALNLELLNKENEF---KLWENEAAAFYHDLQMSSICLALLESKVSELTGVCKILD 1253
               + +L+ EL +  NE    +    E  A   D+      L+ LE K SEL    +   
Sbjct: 86   LDEQASLSAELEDLRNELEDQRAKNKELEACCKDMDALEKKLSELEKKRSELEKELEDNR 145

Query: 1254 DESSAKSLENEHMREIISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLEHISLLWTKRNS 1313
             E      EN  ++++I +  +E    K++L   +     LKED  +L      W +   
Sbjct: 146  GELERLQKENLDLKDVIEVERAE----KDKLRDLLEESKKLKEDNENL------WAQLER 195

Query: 1314 VVGNGAQKDVVIETCLRKHSHQSARENEIVLIPDGVSDLLTLQTRIRAVEKIMMEELKRR 1373
            + G                      EN+         DL+         +K  +E+L ++
Sbjct: 196  LRG----------------------END---------DLMG--------QKKALEDLNKQ 216

Query: 1374 VKQKSLTTESTPYSSLEIATYPKVENRKKEIELVEENVFDRNSWRKKPKIRLLMKDIPLD 1433
            + + + + + T   +LE A    + N    +E   + + D N   K+   R L ++  L 
Sbjct: 217  LNEDNESMKRT-MGNLE-ARIDSLSNELSNVERERDALLDENESVKRELERTLTENENLK 274

Query: 1434 RNVDDQNSKYLKREHRRTNDHVLELCENNEHEPLSAPTVDHAMICHRSD--DSGRYLNYS 1491
              +D  + +  K +  R      EL  N +   L   T+   +   + D  +S R     
Sbjct: 275  TELDKADEQLDKLKTERN-----ELQRNFDTMKLENETLKENVKALKDDLEESKR----- 324

Query: 1492 SELDIEKELGVDKLELSKSVKEKTEDDKRRILERLSSDGQKLAI----LKMALQDLKKKT 1547
             E+D  K +G D L+  + +K+    + ++ ++ L ++  +L      L+    +L+ K 
Sbjct: 325  -EVDEMKAVG-DALKDKEELKDAEFRELQQNMQNLKTENGELKKENDDLRTRSSELEHKL 382

Query: 1548 ETKKKSKQGNDIEYETVKRHIEEVEEAVMQQVSINDQMAKNVEEGASSLDREIPRRGSEQ 1607
            +  KK     + E   ++  I+ +E+ + +     +Q+   +     +LD+ +      +
Sbjct: 383  DNVKKELDKVESENADLRAKIDNLEKELEKDKKEIEQLKLEISSLKDALDKCVDEMEKLK 442

Query: 1608 IGKLQFEVQNIQYILLKLAEENNNKVKN 1635
            +   + + + ++     L E  N K KN
Sbjct: 443  VENEKLKKEGMKVEATWLEENVNLKAKN 470


>UniRef100_UPI0000432991 UPI0000432991 UniRef100 entry
          Length = 1210

 Score =  181 bits (458), Expect = 2e-43
 Identities = 267/1241 (21%), Positives = 517/1241 (41%), Gaps = 151/1241 (12%)

Query: 145  EESNGEVQTLREALAKMQS---DKDALFLQYQESLENLSKMETDLNKAQNNARGLDDRAS 201
            E+   E++  R    ++++   D DAL    ++ L  L K  ++L K   + RG  +R  
Sbjct: 3    EDLRNELEDQRAKNKELEACCKDMDAL----EKKLSELEKKRSELEKELEDNRGELERLQ 58

Query: 202  EAEIQVEILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIEAKNLKQELTRVV 261
            +  +    LK+ +   +A+KD    L           ES   ++DN   +NL  +L R+ 
Sbjct: 59   KENLD---LKDVIEVERAEKDKLRDLLE---------ESKKLKEDN---ENLWAQLERLR 103

Query: 262  VQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVETLRKNLAEMNEERD 321
             + D ++ Q K+ LE +    NK  L E+N  M    +   E  +++L   L+ +  ERD
Sbjct: 104  GENDDLMGQ-KKALEDL----NK-QLNEDNESMKRT-MGNLEARIDSLSNELSNVERERD 156

Query: 322  SLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQL 381
            +L       L++   ++ E+       E LK +++K  E+L+  +  R  L+++   ++L
Sbjct: 157  AL-------LDENESVKRELERTLTENENLKTELDKADEQLDKLKTERNELQRNFDTMKL 209

Query: 382  EAENLVQRIASKDHELLEKHTEIERLQTLMHG-------EHSNFIQIESALQALQKLYSQ 434
            E E L + + +   +L E   E++ ++ +          + + F +++  +Q L+    +
Sbjct: 210  ENETLKENVKALKDDLEESKREVDEMKAVGDALKDKEELKDAEFRELQQNMQNLKTENGE 269

Query: 435  SQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQ--- 491
             +KE  +L            +LE    + K+E+  +  EN  L     +  + L+K    
Sbjct: 270  LKKENDDLRTR-------SSELEHKLDNVKKELDKVESENADLRAKIDNLEKELEKDKKE 322

Query: 492  ----QMEISKLKEIKEKLEREFHTSTEESNVLQRETHQIK----DDIQHLNERYQAMLEQ 543
                ++EIS LK+  +K   E      E+  L++E  +++    ++  +L  +   + E 
Sbjct: 323  IEQLKLEISSLKDALDKCVDEMEKLKVENEKLKKEGMKVEATWLEENVNLKAKNTELEEN 382

Query: 544  LQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREK-------SKDMNEVLMEN 596
            L +     +   +   DL +E   LK+  +    E + L+ +         D  +  +E+
Sbjct: 383  LANTVNELDKMRSENADLLSELNRLKQELESGRKEIDQLKSEIDSDLRAEVDRLKKELES 442

Query: 597  ACMEFSLL--GLNDELDGLRGTVKEIQQFCQVLQEEKSI---LADEKSTLLSQLQIITES 651
            A  E   L   +N   +GL   V+E+++      E KS    L  E  +L S+L  + + 
Sbjct: 443  AGKEIDQLKAEMNSLKNGLNKCVEEMEKLTNENSELKSQVHGLRGEGDSLASELTNVKDE 502

Query: 652  MQKILENNTVLEKSLSDAKIEFEGLRIKSGDLE----------DCCK----LLNDEKNNL 697
               + +    L K L++ K E E L+ ++ +LE          + CK     L +E N L
Sbjct: 503  NSALKDEKDQLNKQLAENKTENERLKKQNDELESENTKIKKELESCKNENNNLKEENNKL 562

Query: 698  QNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENH 757
            + E   L  QL+ + ++ + L +++   E+K   +E     A ++ E+    + V +   
Sbjct: 563  KEELEKLGEQLKSLNDETNKLRRELKEAEDKIQILEPQLSRARSENEKSQNELAVLRNEA 622

Query: 758  SNHKHSSEARL---ANLENIVRVLQEE-----QRLGKVEFEQELDRVVNAQIEMFILQNC 809
            +  K   +  +    N+ N +++L+++     ++L     E +  +  N  ++  +    
Sbjct: 623  NELKVKLDREMLDNTNMRNALKILEDQVLDLNKKLDNCREENDALKEENKDLKTKLSDTG 682

Query: 810  IEELELKNFVLLTECEKLVEASKFSDKVISELESENLMQLIEEEFLLHRIRKFKMDIHKV 869
               L LK     TEC+ L E      K I +L+ +   Q  E +       KF++D  K+
Sbjct: 683  QVVLNLK-----TECDNLKEDIASLQKTIEQLKQKIADQEAEIDHWKVEHCKFELDNEKL 737

Query: 870  CGVLQ---------IDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVEN 920
               L+          D       E+   +   +++L    SLE    K + E     VE 
Sbjct: 738  KADLEKVLKDLNECQDDYSRLTTELDGLKSENTKLLQDKRSLEDEFGKLRGEGDGQRVEI 797

Query: 921  SVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGV 980
              L  +L   ++  EKLK + ++ + E + ++ Q   +++   ++  EN +L+ EV    
Sbjct: 798  DRLRTTLDAEKTAAEKLKSDLQSCKDENDKLQTQINEMKRSLDKMGTENDRLKREV---- 853

Query: 981  EKENRSKSTLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENS 1040
               + S+  L  ++A++  L         E  +++ E   L R   DL + ++  E +  
Sbjct: 854  ---DESRKKLEDMEAKVKSLENQLSNLSAEKEELVKE---LYRTREDLNNLRNELEKQTG 907

Query: 1041 VMFHDVLALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEA 1100
            V   D +   + NL  E+   +  + K    +    L + N+ LN E   L K  +  + 
Sbjct: 908  V--KDTMEKESTNLKEELKALKEELNKTR--DENDRLKNENDKLNAEIARLNKQLDALKD 963

Query: 1101 ENVYLNESIERMDKELLEMDKRLKAAETSNAEFSRHIEELKMEQ----------EESTKI 1150
            E+  L   IE +++   E+ K L  A+ +       +  LK E           E+S + 
Sbjct: 964  ESANLKNDIENLNERNAELSKELAVAKDNLMGMETRLSNLKKENDDMKNKIITLEDSIQE 1023

Query: 1151 KENLDRQILEQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNL--ELL 1208
             ++L RQ+ E  +       E++ L   N+ LQ ++            R E+LNL  +L 
Sbjct: 1024 VDDLKRQLKEAKKELDKPSPELDTLKSTNKKLQDDL---------DNARNESLNLKNDLD 1074

Query: 1209 NKENEFKLWENEAAAFYHDLQMSSICLALLESKV-------SELTGVCKILDDESSAKSL 1261
            N +N++   + E A    +        A LE  +        EL    + L  E      
Sbjct: 1075 NLQNDYNNLQTELADVKEERDTFRERAAALEKDLVRVKRENEELVEQNETLRTELDDCRG 1134

Query: 1262 ENEHMREIISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLE 1302
            EN  + + +  L+SE   L++ L         LKED N L+
Sbjct: 1135 ENNRLLKELEKLKSENVKLQDNLINARSEGERLKEDLNKLK 1175



 Score =  166 bits (421), Expect = 4e-39
 Identities = 241/1125 (21%), Positives = 480/1125 (42%), Gaps = 161/1125 (14%)

Query: 29   LLENLTDIDTKVKSMIKLIEEEADSFARRAEMYYKKRPELMKLVEEFYRAYRALAERYDH 88
            L + L + +  +K  +  +E   DS +       ++R  L+   E   R         ++
Sbjct: 119  LNKQLNEDNESMKRTMGNLEARIDSLSNELSNVERERDALLDENESVKRELERTLTENEN 178

Query: 89   AMGELRHAHKTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARPTHRSKKNERSSEESN 148
               EL  A + + +          N D+         E+ T        K +   S+   
Sbjct: 179  LKTELDKADEQLDKLKTERNELQRNFDTM------KLENETLKENVKALKDDLEESKREV 232

Query: 149  GEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNKAQNNARGLDDRASEAEIQVE 208
             E++ + +AL   +  KDA F + Q++++NL     +L K  ++ R    R+SE E +++
Sbjct: 233  DEMKAVGDALKDKEELKDAEFRELQQNMQNLKTENGELKKENDDLR---TRSSELEHKLD 289

Query: 209  ILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDNIEAKNLKQELTRVVVQKDTVL 268
             +K+ L +++++              I  LE  L +KD  E + LK E++ +        
Sbjct: 290  NVKKELDKVESENA-------DLRAKIDNLEKEL-EKDKKEIEQLKLEISSL-------- 333

Query: 269  LQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVET--------LRKNLAEMNEER 320
               K  L+K      K+ +  E  +    ++E T LE           L +NLA    E 
Sbjct: 334  ---KDALDKCVDEMEKLKVENEKLKKEGMKVEATWLEENVNLKAKNTELEENLANTVNEL 390

Query: 321  DSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEKHRGMLEKSNQNLQ 380
            D +       L ++++++ E+   ++  +QLK++I+ +  + E+    + +     +  Q
Sbjct: 391  DKMRSENADLLSELNRLKQELESGRKEIDQLKSEIDSDL-RAEVDRLKKELESAGKEIDQ 449

Query: 381  LEAE-NLVQRIASKDHELLEKHT-EIERLQTLMHGEHSNFIQIESALQALQKLYS--QSQ 436
            L+AE N ++   +K  E +EK T E   L++ +HG       + S L  ++   S  + +
Sbjct: 450  LKAEMNSLKNGLNKCVEEMEKLTNENSELKSQVHGLRGEGDSLASELTNVKDENSALKDE 509

Query: 437  KEQRNLAL-ELKYGLLLLK----DLELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQ 491
            K+Q N  L E K     LK    +LE      K+E++    EN  L E N          
Sbjct: 510  KDQLNKQLAENKTENERLKKQNDELESENTKIKKELESCKNENNNLKEEN---------- 559

Query: 492  QMEISKLKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHL----------NERYQAML 541
                +KLKE  EKL  +  +  +E+N L+RE  + +D IQ L          NE+ Q  L
Sbjct: 560  ----NKLKEELEKLGEQLKSLNDETNKLRRELKEAEDKIQILEPQLSRARSENEKSQNEL 615

Query: 542  EQLQSLG-----------LNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDMN 590
              L++             L+  +   +++ L+++   L +       E +AL+E++KD+ 
Sbjct: 616  AVLRNEANELKVKLDREMLDNTNMRNALKILEDQVLDLNKKLDNCREENDALKEENKDLK 675

Query: 591  EVLMENACMEFSLL----GLNDELDGLRGTVKEIQQ---------------FCQVLQEEK 631
              L +   +  +L      L +++  L+ T+++++Q                C+   + +
Sbjct: 676  TKLSDTGQVVLNLKTECDNLKEDIASLQKTIEQLKQKIADQEAEIDHWKVEHCKFELDNE 735

Query: 632  SILAD-------------EKSTLLSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRI 678
             + AD             + S L ++L  +     K+L++   LE      + E +G R+
Sbjct: 736  KLKADLEKVLKDLNECQDDYSRLTTELDGLKSENTKLLQDKRSLEDEFGKLRGEGDGQRV 795

Query: 679  K------------------SGDLEDCC----KL---LNDEKNNLQN---ERSMLISQLEI 710
            +                    DL+ C     KL   +N+ K +L     E   L  +++ 
Sbjct: 796  EIDRLRTTLDAEKTAAEKLKSDLQSCKDENDKLQTQINEMKRSLDKMGTENDRLKREVDE 855

Query: 711  VEEKLSNLEKKVTNLEEKYADVEKDKESAVNQV---EELFASILVQKENHSNHKHSSEAR 767
              +KL ++E KV +LE + +++  +KE  V ++    E   ++  + E  +  K + E  
Sbjct: 856  SRKKLEDMEAKVKSLENQLSNLSAEKEELVKELYRTREDLNNLRNELEKQTGVKDTMEKE 915

Query: 768  LANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQNCIEELELKNFVLLTECEKL 827
              NL+  ++ L+EE    + E ++  +       E+  L   ++ L+ ++  L  + E L
Sbjct: 916  STNLKEELKALKEELNKTRDENDRLKNENDKLNAEIARLNKQLDALKDESANLKNDIENL 975

Query: 828  VEASKFSDKVISELESENLMQLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKK 887
             E +    K ++ +  +NLM +   E  L  ++K   D+     ++ ++      +++K+
Sbjct: 976  NERNAELSKELA-VAKDNLMGM---ETRLSNLKKENDDMKNK--IITLEDSIQEVDDLKR 1029

Query: 888  EEIPISRILDK----IESLESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLEKKT 943
            +     + LDK    +++L+S+  K Q++      E+  L   L   Q++   L+ E   
Sbjct: 1030 QLKEAKKELDKPSPELDTLKSTNKKLQDDLDNARNESLNLKNDLDNLQNDYNNLQTELAD 1089

Query: 944  VEQEFENMREQNVILQKDKV-------ELLEENRQLRIEVVNGVEKENRSKSTLAALQAE 996
            V++E +  RE+   L+KD V       EL+E+N  LR E+ +   + NR    L  L++E
Sbjct: 1090 VKEERDTFRERAAALEKDLVRVKRENEELVEQNETLRTELDDCRGENNRLLKELEKLKSE 1149

Query: 997  MIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSV 1041
             ++L+      + E  ++ ++ N L ++ SDL+   + A ++  V
Sbjct: 1150 NVKLQDNLINARSEGERLKEDLNKLKKDYSDLRTDLTKAREDRDV 1194



 Score =  155 bits (392), Expect = 1e-35
 Identities = 272/1289 (21%), Positives = 530/1289 (41%), Gaps = 153/1289 (11%)

Query: 349  EQLKNKIEKEAEK---LEISEKHRGMLEKSNQNLQLEAENLVQRIASKDHELLEKHTEIE 405
            E L+N++E +  K   LE   K    LEK    L+ +   L       + EL +   E+E
Sbjct: 3    EDLRNELEDQRAKNKELEACCKDMDALEKKLSELEKKRSEL-------EKELEDNRGELE 55

Query: 406  RLQTLMHGEHSNFIQIESALQ-ALQKLYSQSQK---EQRNLALELKYGLLLLKDLELSKQ 461
            RLQ   + +  + I++E A +  L+ L  +S+K   +  NL  +L+        L     
Sbjct: 56   RLQK-ENLDLKDVIEVERAEKDKLRDLLEESKKLKEDNENLWAQLER-------LRGEND 107

Query: 462  DFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEISKLKEIKEKLEREFHTSTEESNVLQR 521
            D   + + + + NK L+E N S  R++   +  I  L      +ERE     +E+  ++R
Sbjct: 108  DLMGQKKALEDLNKQLNEDNESMKRTMGNLEARIDSLSNELSNVERERDALLDENESVKR 167

Query: 522  ETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEA 581
            E  +   + ++L        EQL  L    N    +   ++ EN  LKE  K   + K+ 
Sbjct: 168  ELERTLTENENLKTELDKADEQLDKLKTERNELQRNFDTMKLENETLKENVK---ALKDD 224

Query: 582  LREKSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTL 641
            L E  ++++E+      ++      + E   L+  ++ ++     L++E   L    S L
Sbjct: 225  LEESKREVDEMKAVGDALKDKEELKDAEFRELQQNMQNLKTENGELKKENDDLRTRSSEL 284

Query: 642  LSQLQIITESMQKILENNT-------VLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEK 694
              +L  + + + K+   N         LEK L   K E E L+++   L+D      DE 
Sbjct: 285  EHKLDNVKKELDKVESENADLRAKIDNLEKELEKDKKEIEQLKLEISSLKDALDKCVDEM 344

Query: 695  NNLQNERSMLISQLEIVE----EKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASI 750
              L+ E   L  +   VE    E+  NL+ K T LEE  A+   + +   ++  +L + +
Sbjct: 345  EKLKVENEKLKKEGMKVEATWLEENVNLKAKNTELEENLANTVNELDKMRSENADLLSEL 404

Query: 751  LVQKENHSNHKHSSEARLANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQN-- 808
               K+   + +   +   + +++ +R   E  RL K E E     +   + EM  L+N  
Sbjct: 405  NRLKQELESGRKEIDQLKSEIDSDLRA--EVDRL-KKELESAGKEIDQLKAEMNSLKNGL 461

Query: 809  --CIEELEL---KNFVLLTECEKLVEASKFSDKVISELESENLMQLIEEEFLLHRIRKFK 863
              C+EE+E    +N  L ++   L          ++ ++ EN     E++ L  ++ + K
Sbjct: 462  NKCVEEMEKLTNENSELKSQVHGLRGEGDSLASELTNVKDENSALKDEKDQLNKQLAENK 521

Query: 864  MDIHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSVL 923
             +  ++    Q D     + +IKKE          +ES ++     +EEN +L  E   L
Sbjct: 522  TENERL--KKQNDELESENTKIKKE----------LESCKNENNNLKEENNKLKEELEKL 569

Query: 924  LGSLQQHQSEGEKLKLEKKTVEQEFE-------NMREQNVILQKDKVELLEENRQLRIEV 976
               L+    E  KL+ E K  E + +         R +N   Q +   L  E  +L++++
Sbjct: 570  GEQLKSLNDETNKLRRELKEAEDKIQILEPQLSRARSENEKSQNELAVLRNEANELKVKL 629

Query: 977  VNGVEKENRSKSTLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAE 1036
               +      ++ L  L+ ++++L +     +EEN  + +E   L   +SD      + +
Sbjct: 630  DREMLDNTNMRNALKILEDQVLDLNKKLDNCREENDALKEENKDLKTKLSDTGQVVLNLK 689

Query: 1037 DENSVMFHDVLALSNL--NLVYEIFFTENMVEKRALCEHL----------GNLSHLNNDL 1084
             E   +  D+ +L      L  +I   E  ++   + EH            +L  +  DL
Sbjct: 690  TECDNLKEDIASLQKTIEQLKQKIADQEAEIDHWKV-EHCKFELDNEKLKADLEKVLKDL 748

Query: 1085 NQ---EFGVLRKNFEVKEAENVYLNESIERMDKEL-----------LEMDK---RLKAAE 1127
            N+   ++  L    +  ++EN  L +    ++ E            +E+D+    L A +
Sbjct: 749  NECQDDYSRLTTELDGLKSENTKLLQDKRSLEDEFGKLRGEGDGQRVEIDRLRTTLDAEK 808

Query: 1128 TSNAEFSRHIEELKME----QEESTKIKENLDRQILEQSENCMNHKKEIEHLNEANETLQ 1183
            T+  +    ++  K E    Q +  ++K +LD+   E        K+E++   +  E ++
Sbjct: 809  TAAEKLKSDLQSCKDENDKLQTQINEMKRSLDKMGTEND----RLKREVDESRKKLEDME 864

Query: 1184 FEMKTLLHEVEQHRVREEALNLELLNKENEFKLWENEAAAFYHDLQMSSICLALLESKVS 1243
             ++K+L +++      +E L  EL     +     NE       L+  +     +E + +
Sbjct: 865  AKVKSLENQLSNLSAEKEELVKELYRTREDLNNLRNE-------LEKQTGVKDTMEKEST 917

Query: 1244 ELTGVCKILDDESSAKSLENEHMREIISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLEH 1303
             L    K L +E +    EN+ ++     L +EI  L +QL A     ++LK D  +L  
Sbjct: 918  NLKEELKALKEELNKTRDENDRLKNENDKLNAEIARLNKQLDALKDESANLKNDIENLNE 977

Query: 1304 ISLLWTKRNSVVGNGAQKDVVIETCLRKHSHQSARENEIVLIPDGVSDLLTLQTRIRAVE 1363
             +   +K  +V  +         + L+K +     +N+I+ + D + +            
Sbjct: 978  RNAELSKELAVAKDNLMGMETRLSNLKKENDD--MKNKIITLEDSIQE------------ 1023

Query: 1364 KIMMEELKRRVKQ--KSLTTESTPYSSLEIATYPKVEN-----RKKEIELVEENVFDRNS 1416
               +++LKR++K+  K L   S    +L+ +T  K+++     R + + L  +N  D N 
Sbjct: 1024 ---VDDLKRQLKEAKKELDKPSPELDTLK-STNKKLQDDLDNARNESLNL--KNDLD-NL 1076

Query: 1417 WRKKPKIRLLMKDIPLDRNVDDQNSKYLKREHRRTNDHVLELCENNEHEPLSAPTVDHAM 1476
                  ++  + D+  +R+   + +  L+++  R      EL E N  E L     D   
Sbjct: 1077 QNDYNNLQTELADVKEERDTFRERAAALEKDLVRVKRENEELVEQN--ETLRTELDD--- 1131

Query: 1477 ICHRSDDSGRYLNYSSELDIEKELGVDKLELSKSVKEKTEDDKRRILERLSSDGQKLAIL 1536
             C    ++ R L    +L  E     D L  ++S  E+ ++D    L +L  D    + L
Sbjct: 1132 -CR--GENNRLLKELEKLKSENVKLQDNLINARSEGERLKED----LNKLKKD---YSDL 1181

Query: 1537 KMALQDLKKKTETKKKSKQGNDIEYETVK 1565
            +  L   ++  + +K+     D E + +K
Sbjct: 1182 RTDLTKAREDRDVRKEKDMELDKEIDELK 1210



 Score =  153 bits (387), Expect = 4e-35
 Identities = 266/1307 (20%), Positives = 547/1307 (41%), Gaps = 174/1307 (13%)

Query: 403  EIERLQTLMHGEHSNFIQIESA---LQALQKLYSQSQKEQRNLALELKYGL--------- 450
            E+E L+  +  + +   ++E+    + AL+K  S+ +K++  L  EL+            
Sbjct: 1    ELEDLRNELEDQRAKNKELEACCKDMDALEKKLSELEKKRSELEKELEDNRGELERLQKE 60

Query: 451  -LLLKDLELSKQDFKEEMQGIVEENKTLHELNFSSTRSLKKQQMEISKLKEIKEKLEREF 509
             L LKD+   ++  K++++ ++EE+K L E N +    L++ + E   L   K+ LE   
Sbjct: 61   NLDLKDVIEVERAEKDKLRDLLEESKKLKEDNENLWAQLERLRGENDDLMGQKKALEDLN 120

Query: 510  HTSTEESNVLQRETHQIKDDIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLK 569
                E++  ++R    ++  I  L+     +  +  +L     S    +     EN  LK
Sbjct: 121  KQLNEDNESMKRTMGNLEARIDSLSNELSNVERERDALLDENESVKRELERTLTENENLK 180

Query: 570  ETCKKEHSEKEALR----EKSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQ 625
                K   + + L+    E  ++ + + +EN  ++ ++  L D+L+  +  V E++    
Sbjct: 181  TELDKADEQLDKLKTERNELQRNFDTMKLENETLKENVKALKDDLEESKREVDEMKAVGD 240

Query: 626  VLQEEKSILADEKSTLLSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLED 685
             L++++ +    K     +LQ   ++MQ +   N  L+K   D       LR +S +LE 
Sbjct: 241  ALKDKEEL----KDAEFRELQ---QNMQNLKTENGELKKENDD-------LRTRSSELEH 286

Query: 686  CCKLLNDEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEE 745
                +  E + +++E + L ++++ +E++L   +K++  L+ + + ++   +  V+++E+
Sbjct: 287  KLDNVKKELDKVESENADLRAKIDNLEKELEKDKKEIEQLKLEISSLKDALDKCVDEMEK 346

Query: 746  LFASILVQKENHSNHKHSSEARLANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFI 805
            L      + EN    K   +     LE  V +     +    E E+ L   VN       
Sbjct: 347  L------KVENEKLKKEGMKVEATWLEENVNL-----KAKNTELEENLANTVNE------ 389

Query: 806  LQNCIEELELKNFVLLTECEKLVEASKFSDKVISELESENLMQLIEEEFLLHRIRKFKMD 865
                ++++  +N  LL+E  +L +  +   K I +L+SE    L  E   + R++K    
Sbjct: 390  ----LDKMRSENADLLSELNRLKQELESGRKEIDQLKSEIDSDLRAE---VDRLKK---- 438

Query: 866  IHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSVLLG 925
                    +++S G   +++K E          + SL++ L K  EE ++L  ENS L  
Sbjct: 439  --------ELESAGKEIDQLKAE----------MNSLKNGLNKCVEEMEKLTNENSELKS 480

Query: 926  SLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKENR 985
             +   + EG+ L         E  N++++N  L+ +K +L   N+QL     N  E E R
Sbjct: 481  QVHGLRGEGDSL-------ASELTNVKDENSALKDEKDQL---NKQL---AENKTENE-R 526

Query: 986  SKSTLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHD 1045
             K     L++E  ++++  +  + EN  + +E N L   +  L +   S  DE + +  +
Sbjct: 527  LKKQNDELESENTKIKKELESCKNENNNLKEENNKLKEELEKLGEQLKSLNDETNKLRRE 586

Query: 1046 VLALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENVYL 1105
            +    +   + E   +    E     +    L+ L N+ N+    L+   + +  +N  +
Sbjct: 587  LKEAEDKIQILEPQLSRARSENE---KSQNELAVLRNEANE----LKVKLDREMLDNTNM 639

Query: 1106 NESIERMDKELLEMDKRLKAAETSNAEFSRHIEELKMEQEESTKIKENLDRQILEQSENC 1165
              +++ ++ ++L+++K+L      N       ++LK +  ++ ++  NL  +       C
Sbjct: 640  RNALKILEDQVLDLNKKLDNCREENDALKEENKDLKTKLSDTGQVVLNLKTE-------C 692

Query: 1166 MNHKKEIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLELLNKENEFKLWE-----NE 1220
             N K++I  L +  E  Q + K    E E    + E    EL N++ +  L +     NE
Sbjct: 693  DNLKEDIASLQKTIE--QLKQKIADQEAEIDHWKVEHCKFELDNEKLKADLEKVLKDLNE 750

Query: 1221 AAAFYHDLQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMREIISLLESEIGGL 1280
                Y  L      L  L+S+ ++L    + L+DE      E +  R  I  L + +   
Sbjct: 751  CQDDYSRLTTE---LDGLKSENTKLLQDKRSLEDEFGKLRGEGDGQRVEIDRLRTTLDAE 807

Query: 1281 KEQLSAYVPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVIETCLRKHSHQSAREN 1340
            K         + S K++ + L+  + +   + S+   G + D +              E 
Sbjct: 808  KTAAEKLKSDLQSCKDENDKLQ--TQINEMKRSLDKMGTENDRLKREVDESRKKLEDMEA 865

Query: 1341 EIVLIPDGVSDLLTLQTRIRAVEKIMMEELKRRVKQKSLTTESTPYSSLEIATYPKVENR 1400
            ++  + + +S+L   +      E+++ E  + R    +L  E    + ++     +  N 
Sbjct: 866  KVKSLENQLSNLSAEK------EELVKELYRTREDLNNLRNELEKQTGVKDTMEKESTNL 919

Query: 1401 KKEIELVEENV---FDRNSWRKKPKIRLLMKDIPLDRNVD--DQNSKYLKREHRRTNDHV 1455
            K+E++ ++E +    D N   K    +L  +   L++ +D     S  LK +    N+  
Sbjct: 920  KEELKALKEELNKTRDENDRLKNENDKLNAEIARLNKQLDALKDESANLKNDIENLNERN 979

Query: 1456 LELCE-------------------NNEHEPLSAPTVDHAMICHRSDDSGRYLNYSSELDI 1496
             EL +                     E++ +    +         DD  R L      + 
Sbjct: 980  AELSKELAVAKDNLMGMETRLSNLKKENDDMKNKIITLEDSIQEVDDLKRQLK-----EA 1034

Query: 1497 EKELGVDKLELS--KSVKEKTEDD----------KRRILERLSSDGQKLAILKMALQDLK 1544
            +KEL     EL   KS  +K +DD           +  L+ L +D      L+  L D+K
Sbjct: 1035 KKELDKPSPELDTLKSTNKKLQDDLDNARNESLNLKNDLDNLQNDYNN---LQTELADVK 1091

Query: 1545 KKTETKKKSKQGNDIEYETVKRHIEE-VEEAVMQQVSINDQMAKNVEEGASSLDREIPRR 1603
            ++ +T ++     + +   VKR  EE VE+    +  ++D   +N     + L +E+ + 
Sbjct: 1092 EERDTFRERAAALEKDLVRVKRENEELVEQNETLRTELDDCRGEN-----NRLLKELEKL 1146

Query: 1604 GSEQIGKLQFEVQNIQYILLKLAEENNNKVKNRISRKTGILLRRKLR 1650
             SE + KLQ  + N +    +L E+ N   K+    +T +   R+ R
Sbjct: 1147 KSENV-KLQDNLINARSEGERLKEDLNKLKKDYSDLRTDLTKAREDR 1192


>UniRef100_Q5QMF3 Putative kinase interacting protein 1 [Oryza sativa]
          Length = 840

 Score =  179 bits (455), Expect = 5e-43
 Identities = 188/791 (23%), Positives = 364/791 (45%), Gaps = 92/791 (11%)

Query: 13  YSWWWDSHNSPKNSKWLLENLTDIDTKVKSMIKLIEEEADSFARRAEMYYKKRPELMKLV 72
           YSWWW SH     SKWL  N+ +++ +VK+MIKLI+ EAD+FAR+A++Y+K RP+L+  V
Sbjct: 10  YSWWWASHIRTTQSKWLDNNVQEMEIRVKAMIKLIDIEADTFARKADLYFKSRPDLINHV 69

Query: 73  EEFYRAYRALAERYDHAMGELRHAHKTMPEAFPNSAYYILNDDS----PCGSLGPDAESH 128
           EE YR+Y+ALA+RYD   GEL  ++ T+  AFP      L DD+    P G  G +    
Sbjct: 70  EETYRSYQALADRYDRVSGELHKSNHTIATAFPEQVQLSLQDDNGDGFPKGITGININRG 129

Query: 129 TSARP----THRSKKNERSSEESNGEVQTLREALAKMQSDKDALFLQYQESLENLSKMET 184
           TSA P    TH+   ++ S +++  E++ L++ +  +Q++K+     Y+ SL     +E 
Sbjct: 130 TSAAPKRTQTHKKISSKMSKDKAQEEIERLQKKILVLQTEKEFFKSSYESSLNKYLSIER 189

Query: 185 DLNKAQNNARGLDDRASEAEIQVEILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQ 244
              + Q     L +  S + +  +    +LM  +A           C + +A L     Q
Sbjct: 190 QAAEMQEEVWSLQETFSTSAVIEDNEARALMAAQA--------LISCEDKLASLH--CEQ 239

Query: 245 KDNIEAKNLKQELTRVVVQKDTVLLQYKQC-----LEKIPMLE----NKIALAEENSRML 295
           K + E   +  E+ RV+  K  + +   +C      + +P  +    + I  + E+S ++
Sbjct: 240 KRSYEETTM--EIQRVIDAKKKITIFKSECGYPDDQKDLPNHQDIEFSSIPSSIEDSDLI 297

Query: 296 NDQIERTELEVETLRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKI 355
              ++  +LE++ L + + +  E     S +  H   ++ ++ ++++ ++  A     +I
Sbjct: 298 ---MKDCKLELQELSQKVKQKFESSSEASAV--HLAGQVDEIVDKVISLEIAASSQNAQI 352

Query: 356 EKEAEKLEISEKHRGMLEKSNQNLQLEAENLVQRIASKDHELLEKHTEIERLQTLMHGEH 415
            +   + +  +K    LE     L  ++  L +R+   +  L      I+R+   +H E+
Sbjct: 353 NRMKNEADELQKRLDSLEDEKAALIEDSSKLSERLKQVEEVL----QTIQRIGKSVHSEN 408

Query: 416 SNFIQ-----IESALQALQKLYSQSQKEQRNLALELKYGLL-------LLKDLELSKQDF 463
            N  Q      +S    ++KL + S  E  N + +   G+        LL  L+ S +  
Sbjct: 409 GNIHQQLTEVDDSLNDFVKKLDAHSTDEIVNSSQD-DSGIACKSKDEGLLDALDDSSKAH 467

Query: 464 KEE-----------MQGIVEENKTLHELNFSSTRSLKKQQMEISKLKEIKEKLEREFH-T 511
           KEE           + G+ +++K L +   S  R+ K  Q ++ ++    EK  RE+H  
Sbjct: 468 KEEPDETLGWQQLDLNGLEDKDKILLKDYASILRNYKDTQKQLLEI----EKRNREYHLE 523

Query: 512 STEESNVLQRETHQIKDDIQHLNERYQAMLEQLQS------LGLNPNSFAASVRDLQNEN 565
           +  E N L+  +    D+I+ L     ++  +L +      +    +S A +   L+N+N
Sbjct: 524 AMSEMNELKSSSATKDDEIRSLRRMLSSLQTKLNNSLPQRFVESEESSEANASPSLENKN 583

Query: 566 FMLKETCKK--EHSEKE--ALREKSK-DMNEVLMENACMEFSLLGLNDELDGLRGTVKEI 620
               E   K  EH E    +L +K + +++ +L EN  ++F L             +++ 
Sbjct: 584 IAETEEYMKIREHEEPHDPSLEDKFRAEISRILEEN--LDFWL-----RFSTSYHYMQKF 636

Query: 621 QQFCQVLQEEKSILADEKSTLLSQLQIITESMQKILENNTVLEKSL----SDAKIEFEGL 676
           Q+     + E   L D K+   S      +S +K  + + VLEK L    +D ++  E  
Sbjct: 637 QKSFDKAKAEMDKLTDAKAQEGSDAVPSCQSARK--QESAVLEKKLRGLSTDLQVWLEKN 694

Query: 677 RIKSGDLEDCCKLLNDEKNNLQNERSM-LISQLEIVEEKLSNLEKKVTNLEEKYADVEKD 735
            +  G+LE    LL   +  +    ++    +      + +  + +V++++++ + V K+
Sbjct: 695 VLLQGELESRFSLLCSIEEEISKITALGQTDEAHFTPFQAAKFQGEVSSMKQENSKVTKE 754

Query: 736 KESAVNQVEEL 746
            ++ ++ V  L
Sbjct: 755 LQTGMDHVRSL 765



 Score = 49.7 bits (117), Expect = 8e-04
 Identities = 112/619 (18%), Positives = 253/619 (40%), Gaps = 103/619 (16%)

Query: 692  DEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFASIL 751
            +E   LQ +  +L ++ E  +    +   K  ++E + A+++++    V  ++E F++  
Sbjct: 154  EEIERLQKKILVLQTEKEFFKSSYESSLNKYLSIERQAAEMQEE----VWSLQETFSTSA 209

Query: 752  VQKENHSNHKHSSEARLANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQNCIE 811
            V ++N +    +++A L + E+ +  L  EQ+    E   E+ RV++A+ ++ I ++   
Sbjct: 210  VIEDNEARALMAAQA-LISCEDKLASLHCEQKRSYEETTMEIQRVIDAKKKITIFKS--- 265

Query: 812  ELELKNFVLLTECEKLVEASKFSDKVISELESENLMQLIEEEFLLHRIRKFKMDIHKVCG 871
                       EC    +     +    ++E  ++   IE+  L+  ++  K+++ ++  
Sbjct: 266  -----------ECGYPDDQKDLPNH--QDIEFSSIPSSIEDSDLI--MKDCKLELQELSQ 310

Query: 872  VLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSVLLGSLQQHQ 931
             ++   +   +         +  I+DK+ SLE   + +  +N Q+               
Sbjct: 311  KVKQKFESSSEASAVHLAGQVDEIVDKVISLE---IAASSQNAQI--------------- 352

Query: 932  SEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKENRSKSTLA 991
                ++K E   +++  +++ ++   L +D  +L E  +Q+  EV+  +++  +S     
Sbjct: 353  ---NRMKNEADELQKRLDSLEDEKAALIEDSSKLSERLKQVE-EVLQTIQRIGKS----- 403

Query: 992  ALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLK---DAKSSAEDENSVMFHDVLA 1048
                              ENG +  +   +  +++D     DA S+ E  NS      +A
Sbjct: 404  ---------------VHSENGNIHQQLTEVDDSLNDFVKKLDAHSTDEIVNSSQDDSGIA 448

Query: 1049 LSNLNL-VYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNF-----EVKEAEN 1102
              + +  + +     +   K    E LG      N L  +  +L K++       K+ + 
Sbjct: 449  CKSKDEGLLDALDDSSKAHKEEPDETLGWQQLDLNGLEDKDKILLKDYASILRNYKDTQK 508

Query: 1103 VYLNESIERMDKEL-LEMDKRLKAAETSNAEFSRHIEELK-MEQEESTKIKENLDRQILE 1160
              L   IE+ ++E  LE    +   ++S+A     I  L+ M     TK+  +L ++ +E
Sbjct: 509  QLLE--IEKRNREYHLEAMSEMNELKSSSATKDDEIRSLRRMLSSLQTKLNNSLPQRFVE 566

Query: 1161 QSENCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHRVR--EEALNLELLNK-------- 1210
              E+           +EAN +   E K +    E  ++R  EE  +  L +K        
Sbjct: 567  SEES-----------SEANASPSLENKNIAETEEYMKIREHEEPHDPSLEDKFRAEISRI 615

Query: 1211 -ENEFKLWENEAAAFYHDLQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMREI 1269
             E     W   + + YH +Q         ++++ +LT   K  +   +  S ++   +E 
Sbjct: 616  LEENLDFWLRFSTS-YHYMQKFQKSFDKAKAEMDKLTD-AKAQEGSDAVPSCQSARKQE- 672

Query: 1270 ISLLESEIGGLKEQLSAYV 1288
             ++LE ++ GL   L  ++
Sbjct: 673  SAVLEKKLRGLSTDLQVWL 691



 Score = 37.4 bits (85), Expect = 3.9
 Identities = 93/426 (21%), Positives = 173/426 (39%), Gaps = 64/426 (15%)

Query: 806  LQNCIEELELKNFVLLTECEKLVEASKFSDKVISELESE-NLMQLIEEEF-----LLHRI 859
            L N ++E+E++   ++   +  +EA  F+ K     +S  +L+  +EE +     L  R 
Sbjct: 26   LDNNVQEMEIRVKAMIKLID--IEADTFARKADLYFKSRPDLINHVEETYRSYQALADRY 83

Query: 860  RKFKMDIHK------------VCGVLQIDSDGGGDNEIKKEEI-------PISRILDKIE 900
             +   ++HK            V   LQ D+  G    I    I       P      K  
Sbjct: 84   DRVSGELHKSNHTIATAFPEQVQLSLQDDNGDGFPKGITGININRGTSAAPKRTQTHKKI 143

Query: 901  SLESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQK 960
            S + S  K+QEE ++L  +  VL    +  +S  E    +  ++E++   M+E+   LQ+
Sbjct: 144  SSKMSKDKAQEEIERLQKKILVLQTEKEFFKSSYESSLNKYLSIERQAAEMQEEVWSLQE 203

Query: 961  --DKVELLEENRQLRIEVVNGV------------EKENRSKSTLAALQAEMIELRQTNQV 1006
                  ++E+N    +     +            E++   + T   +Q  +I+ ++   +
Sbjct: 204  TFSTSAVIEDNEARALMAAQALISCEDKLASLHCEQKRSYEETTMEIQ-RVIDAKKKITI 262

Query: 1007 FQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVLALSNLNLVYEIFFTENMVE 1066
            F+ E G   D+K+       +     SS ED + +M    L L  L+   +  F E+  E
Sbjct: 263  FKSECGYPDDQKDLPNHQDIEFSSIPSSIEDSDLIMKDCKLELQELSQKVKQKF-ESSSE 321

Query: 1067 KRALCEHLGNLSHLNNDLNQEFGVLRKNFEVKEAENVYLNESIERMDKELLEMDKRLKAA 1126
              A+        HL   +++   ++ K   ++ A +   N  I RM  E  E+ KRL + 
Sbjct: 322  ASAV--------HLAGQVDE---IVDKVISLEIAASSQ-NAQINRMKNEADELQKRLDSL 369

Query: 1127 ETSNA---EFSRHIEELKMEQEESTKIKENLDRQILEQSENCMNHKKEIEHLNEANETLQ 1183
            E   A   E S  + E   + EE  +  + + + +   SEN   H    + L E +++L 
Sbjct: 370  EDEKAALIEDSSKLSERLKQVEEVLQTIQRIGKSV--HSENGNIH----QQLTEVDDSLN 423

Query: 1184 FEMKTL 1189
              +K L
Sbjct: 424  DFVKKL 429


>UniRef100_UPI00004983A5 UPI00004983A5 UniRef100 entry
          Length = 2151

 Score =  179 bits (454), Expect = 6e-43
 Identities = 244/1324 (18%), Positives = 575/1324 (43%), Gaps = 151/1324 (11%)

Query: 128  HTSARPTHRSKKNERSSEESNGEVQTLREALAKMQSDKDALFLQYQESLENLSKMETDLN 187
            +  ARP  + +  E   ++ + E++ L++ LA+    ++A       +   + ++E  + 
Sbjct: 859  YVKARPMLKRRNFEEEGKKKDKEIEDLKKKLAEEIKKREAAENALASATAKIGELEAKIQ 918

Query: 188  KAQNNARGLDDRASEAEIQVEILKESLMQLKADKDAGEVLYNQCLETIARLESMLSQKDN 247
              ++    L+ + S AE+  + L   +  L+ DK+       +  ETI +L+  L     
Sbjct: 919  DLEDKISELESKLSAAELDKQELNLKIENLEEDKE-------ELKETIDKLKGDLKDS-K 970

Query: 248  IEAKNLKQELTRVVVQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIERTELEVE 307
            ++ ++L+ E+T +  Q +T+     +  + I  ++  I   E+    L   I+  E E +
Sbjct: 971  LKGEDLEDEITELNSQINTLNATVDKKDKTIAEMQESIDEKEDEITKLKGDIKLLEEEKD 1030

Query: 308  TLRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHVQENAEQLKNKIEKEAEKLEISEK 367
             L ++ A+++  +D ++   +    +    ++EI  +++  E  +NK +    +L+ ++ 
Sbjct: 1031 DLEQDRADVSATKDDIAKKLNKITIECEDAKDEIAKLEQELEDEENKNKDLTNELQQTQL 1090

Query: 368  HRGMLEKSNQNLQLEAENLVQRIASKDHELLEKHTEIERLQT------------LMHGEH 415
              G  EKS     L A+    + AS + + L ++ E E+L T             + G  
Sbjct: 1091 KLGETEKS-----LAAQVAATKKASDERDTLSQNLENEKLTTKNLTKTKADLEKKISGLK 1145

Query: 416  SNFIQIESALQALQKLYSQSQKEQRNLALELKYGLLLLKDLELSKQDFKEEMQGIVEENK 475
             ++  +E     ++     +Q++ + L  E+  G  + + L+  K++++ ++  + EE +
Sbjct: 1146 QDYEDLEDDKNKIEGDLRNAQRKIKELDDEITKGADVSQYLQKQKEEYESQIAKMQEEKE 1205

Query: 476  TLHELNFSSTRSLKKQQMEISKLKEIKEKLEREFHTSTEESNVLQRETHQIKDDIQHLNE 535
             +     +  +++K++++EI  L+E  ++ E E   + ++   +++E   ++++ +++  
Sbjct: 1206 AIGNDVKNKEKTIKEKELEIQSLQEKLDETEVEKEDAEKKKKEIEKEMKALQEEKENVES 1265

Query: 536  RYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDMNEVLME 595
               +  +  + L  N       + D+  +N  LK   K    + EA   + +D +E  + 
Sbjct: 1266 SKNSTEKDKKKLEDNLKDTQKKLDDMTADNEKLKAKAK----DLEAQLNEVQDNHEKAVA 1321

Query: 596  NACMEFSLLGLND-ELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIITESMQK 654
            +A +       +D EL+ L+  ++ + +   V++ +     +EK+ L  ++    E ++ 
Sbjct: 1322 DAELLNKKKAQSDKELNSLKAELEALTKAKSVVESKNKDSENEKAALSEEIDQANEKLKN 1381

Query: 655  ILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQLEIVEEK 714
            I  +                 LR  + DL++     N++K  ++ +R  L++  + + + 
Sbjct: 1382 IQAD-----------------LRKATADLQEA----NEKKAEVEAQRDKLVADNKKMTKT 1420

Query: 715  LSNL---EKKVTNLEEKYADVEKDKESAVNQVEELFASILVQKENHSNHKHSSEARLANL 771
            L  +   +++ T   E Y  V K KE+    +EE   ++ ++K++  N     E ++  L
Sbjct: 1421 LEEIKARDEENTYKVENYEKVLKRKEA---DLEEANENLDIEKKDRMN----KEKQVKKL 1473

Query: 772  ENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQNCIEELELKNFVLLTECEKLVEAS 831
            E  ++  +++      E +        +  ++  L   +EE +     L T+  KL   +
Sbjct: 1474 EGELKETKDKLNAAIAEKDSIFTAKKQSDADLEELNKTVEEHDEVVAKLNTQITKLTRDN 1533

Query: 832  KFSDKVISELESENLMQLIEEEFLLHRIRKFKMDIHKVCGVLQIDSDGGG---DNEIKKE 888
            + +++ ++EL S+             + +K   ++ +    L+    G G   +NEIK  
Sbjct: 1534 QSAEEELNELRSK-----------ADKDKKKISELEEQVNELESRPVGTGNADENEIKIR 1582

Query: 889  EIPISRILDKIESLESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEF 948
            +  I+ +   +E       + Q  N++L  +N+ L   ++  ++E +KL+  KK +EQ+ 
Sbjct: 1583 DAQIADLNKALEMKGDQNNQLQATNKELKAKNNDLTSKIEITENEMKKLENAKKRLEQDK 1642

Query: 949  EN----MREQNVI---LQKDKVELLEENRQLRIEV-----VNGVEKENRSKSTLAALQAE 996
            +     + EQ +    L+++  +L  E + L+ ++     V   E++ R +S +A L+ +
Sbjct: 1643 DEADKAVSEQTIKRKGLEEEVKKLTTEIQALKFQINAPSSVAQEEEKQRLESDIAELKEQ 1702

Query: 997  MIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVMFHDVLALSNLNLVY 1056
            + + R T    + E  K+  E + +  N+ D+ + +     +NS    ++ +L       
Sbjct: 1703 LEQERTTAANAEAERKKIQAELDEVKFNLEDVTNQREKLVAKNSENDAEIDSLKE----- 1757

Query: 1057 EIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEV---KEAENVYLNESIE--- 1110
                     EK+AL + +  ++  NN LN+E   L + +      +  +V + E  +   
Sbjct: 1758 ---------EKKALEDEIEKITDDNNKLNEEIDSLDRKYNALLDSKDSDVSMKEKFQDEL 1808

Query: 1111 RMDKELLEMDKRLKAAETSNAEFSRHIEELKMEQEESTKIKENLDRQILEQSENCMNHKK 1170
            ++ K+ LE +K+   AET   +  R  +E    Q     +++NLD    E+++   +++ 
Sbjct: 1809 KVTKDALETEKK-NHAETMRLK-GRLEKEAAEVQVRLEALQKNLDLAQQEKAKATKDYR- 1865

Query: 1171 EIEHLNEANETLQFEMKTLLHEVEQHRVREEALNLELLNKENEFKLWENEAAAFYHDLQM 1230
                          E+K+L++E++  + + +    +L +KE+E                 
Sbjct: 1866 ----------AADGELKSLMNELDDVKDQLDKAQDDLADKEDE----------------- 1898

Query: 1231 SSICLALLESKVSELTGVCKILDDESSAKSLENEHMREIISLLESEIGGLKEQLSAYVPL 1290
                LA L+ K   L     + D          + M+E + L ++     ++Q  AY   
Sbjct: 1899 ----LATLDQKYKTLVKQKSVFDSRI-------QEMQEQLDLEKAGRAKAQKQKQAYEKK 1947

Query: 1291 VSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVIETCLRKHSHQSARENEIVLIPDGVS 1350
            +  L+E+ N  E       KR + +   AQKD + +   ++   +   E E+  +     
Sbjct: 1948 LQELQENDNDFEEYKETADKRINTL--SAQKDDLQKELEKERGLKQDSEKEVQRLRVKCQ 2005

Query: 1351 DLLTLQTRIRAVE-KIMMEELKRRVKQKSLTTESTPYSSLEIATYPKVENRKKEIELVEE 1409
            +L T    +      I   + K   + + LTTE+      ++    K +  +K+++ +++
Sbjct: 2006 ELETKVAEVGGANVSIAKVKAKYEAEIEELTTEAEDALKAKMKAEKKAKTSQKKLDELQK 2065

Query: 1410 NVFD 1413
             + D
Sbjct: 2066 TIAD 2069



 Score =  148 bits (374), Expect = 1e-33
 Identities = 275/1405 (19%), Positives = 576/1405 (40%), Gaps = 212/1405 (15%)

Query: 293  RMLNDQIERTELEVETLRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHVQENAEQLK 352
            R   ++ ++ + E+E L+K LAE  ++R++          KI ++E +I       + L+
Sbjct: 869  RNFEEEGKKKDKEIEDLKKKLAEEIKKREAAENALASATAKIGELEAKI-------QDLE 921

Query: 353  NKIEKEAEKLEISEKHRGMLEKSNQNLQLEAENLVQRIASKDHELLEKHTEIERLQTLMH 412
            +KI +   KL  +E  +  L    +NL+ + E L + I     +L +   + E L+  + 
Sbjct: 922  DKISELESKLSAAELDKQELNLKIENLEEDKEELKETIDKLKGDLKDSKLKGEDLEDEIT 981

Query: 413  GEHSNFIQIESALQALQKLYSQSQK---EQRNLALELKYGLLLLKDLELSKQDFKEEMQG 469
              +S    + + +    K  ++ Q+   E+ +   +LK  + LL++    K D +++   
Sbjct: 982  ELNSQINTLNATVDKKDKTIAEMQESIDEKEDEITKLKGDIKLLEE---EKDDLEQDRAD 1038

Query: 470  IVEENKTLHELNFSSTRSLKKQQMEISKLKEIKEKLEREFHTSTEESNVLQRETHQIKDD 529
            +      +        + L K  +E    K+   KLE+E     +E N  +  T++++  
Sbjct: 1039 VSATKDDI-------AKKLNKITIECEDAKDEIAKLEQELE---DEENKNKDLTNELQQT 1088

Query: 530  IQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSKDM 589
               L E  +++  Q+ +     +      ++L+NE    K   K +   ++ +    +D 
Sbjct: 1089 QLKLGETEKSLAAQVAATKKASDERDTLSQNLENEKLTTKNLTKTKADLEKKISGLKQDY 1148

Query: 590  NEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQIIT 649
             ++  +   +E  L     ++  L   + +     Q LQ++K     + + +  + + I 
Sbjct: 1149 EDLEDDKNKIEGDLRNAQRKIKELDDEITKGADVSQYLQKQKEEYESQIAKMQEEKEAIG 1208

Query: 650  ESM--------QKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNER 701
              +        +K LE  ++ EK L + ++E E    K  ++E   K L +EK N+++ +
Sbjct: 1209 NDVKNKEKTIKEKELEIQSLQEK-LDETEVEKEDAEKKKKEIEKEMKALQEEKENVESSK 1267

Query: 702  SMLISQLEIVEEKLSNLEKKVTNL---EEKYADVEKDKESAVNQVEELFASILVQKENHS 758
            +      + +E+ L + +KK+ ++    EK     KD E+ +N+V++     +   E  +
Sbjct: 1268 NSTEKDKKKLEDNLKDTQKKLDDMTADNEKLKAKAKDLEAQLNEVQDNHEKAVADAELLN 1327

Query: 759  NHKHSSEARLANLENIVRVL--------------QEEQRLGKVEFEQELDRVVNAQIEMF 804
              K  S+  L +L+  +  L              + E+     E +Q  +++ N Q ++ 
Sbjct: 1328 KKKAQSDKELNSLKAELEALTKAKSVVESKNKDSENEKAALSEEIDQANEKLKNIQADLR 1387

Query: 805  ILQNCIEELELKNFVLLTECEKLVEASKFSDKVISELESENLMQLIEEEFLLHRIRKFKM 864
                 ++E   K   +  + +KLV  +K   K + E+++ +     + E     +++ + 
Sbjct: 1388 KATADLQEANEKKAEVEAQRDKLVADNKKMTKTLEEIKARDEENTYKVENYEKVLKRKEA 1447

Query: 865  DIHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSVLL 924
            D+ +    L I+      + + KE+        +++ LE  L +++++    + E   + 
Sbjct: 1448 DLEEANENLDIEKK----DRMNKEK--------QVKKLEGELKETKDKLNAAIAEKDSIF 1495

Query: 925  GSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKEN 984
             + +Q  ++ E+L    KTVE+  E + + N  + K    L  +N+    E+     K +
Sbjct: 1496 TAKKQSDADLEELN---KTVEEHDEVVAKLNTQITK----LTRDNQSAEEELNELRSKAD 1548

Query: 985  RSKSTLAALQAEMIEL--RQTNQVFQEENGKMLDEKNSLCRNVSDLKDAKSSAEDENSVM 1042
            + K  ++ L+ ++ EL  R       +EN   + +       ++DL  A     D+N+ +
Sbjct: 1549 KDKKKISELEEQVNELESRPVGTGNADENEIKIRDAQ-----IADLNKALEMKGDQNNQL 1603

Query: 1043 --FHDVLALSNLNLVYEIFFTENMVEK----------------RALCEHLGNLSHLNND- 1083
               +  L   N +L  +I  TEN ++K                +A+ E       L  + 
Sbjct: 1604 QATNKELKAKNNDLTSKIEITENEMKKLENAKKRLEQDKDEADKAVSEQTIKRKGLEEEV 1663

Query: 1084 --LNQEFGVLRKNFEVKEAENVYLNESIERMDKELLEMDKRLKAAETS--NAEFSR---- 1135
              L  E   L+  F++    +V   E  +R++ ++ E+ ++L+   T+  NAE  R    
Sbjct: 1664 KKLTTEIQALK--FQINAPSSVAQEEEKQRLESDIAELKEQLEQERTTAANAEAERKKIQ 1721

Query: 1136 -HIEELKMEQEESTKIKENLDRQILEQSENCMNHKKEIEHLNEANETLQFEMKTLLHEVE 1194
              ++E+K   E+ T  +E L   + + SEN      EI+ L E       E K L  E+E
Sbjct: 1722 AELDEVKFNLEDVTNQREKL---VAKNSEN----DAEIDSLKE-------EKKALEDEIE 1767

Query: 1195 QHRVREEALNLELLNKENEFKLWENEAAAFYHDLQMSSICLALLESKVSELTGVCKILDD 1254
            +       LN E+ + + ++                     ALL+SK S+++   K  D+
Sbjct: 1768 KITDDNNKLNEEIDSLDRKYN--------------------ALLDSKDSDVSMKEKFQDE 1807

Query: 1255 ESSAK-SLENEHMREIISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLEHISLLWTKRNS 1313
                K +LE E      ++     G L+++ +     + +L+++ +  +      TK + 
Sbjct: 1808 LKVTKDALETEKKNHAETMRLK--GRLEKEAAEVQVRLEALQKNLDLAQQEKAKATK-DY 1864

Query: 1314 VVGNGAQKDVVIETCLRKHSHQSARENEIVLIPDGVSDLLTLQTRIRAVEKIMMEELKRR 1373
               +G  K ++ E    K     A+++    + D   +L TL            ++ K  
Sbjct: 1865 RAADGELKSLMNELDDVKDQLDKAQDD----LADKEDELATLD-----------QKYKTL 1909

Query: 1374 VKQKSL----TTESTPYSSLEIATYPKVENRK----KEIELVEENVFDRNSWRKKPKIRL 1425
            VKQKS+      E      LE A   K + +K    K+++ ++EN  D   +++    R+
Sbjct: 1910 VKQKSVFDSRIQEMQEQLDLEKAGRAKAQKQKQAYEKKLQELQENDNDFEEYKETADKRI 1969

Query: 1426 ----LMKDIPLDRNVDDQNSKYLKREHRRTNDHVLELCENNEHEPLSAPTVDHAMICHRS 1481
                  KD   D   + +  + LK++  +    +   C+  E +                
Sbjct: 1970 NTLSAQKD---DLQKELEKERGLKQDSEKEVQRLRVKCQELETKVA-------------- 2012

Query: 1482 DDSGRYLNYSSELDIEKELGVDKLELSKSVKEKTEDDKRRILERLSSDGQKLAILKMALQ 1541
                             E+G   + ++K VK K E +    +E L+++ +     KM  +
Sbjct: 2013 -----------------EVGGANVSIAK-VKAKYEAE----IEELTTEAEDALKAKMKAE 2050

Query: 1542 DLKKKTETKKKSKQGNDIEYETVKRHIEEVEEAVMQQVSINDQMAKNVEEGASSLDREIP 1601
               K ++ K    Q    +YET +            ++    Q  ++ E   SSL+ EI 
Sbjct: 2051 KKAKTSQKKLDELQKTIADYETKEASFNTQIGKTQAELKKYQQQVRDDETRMSSLEDEI- 2109

Query: 1602 RRGSEQIGKLQFEVQ--NIQYILLK 1624
            ++G++ +   Q E+   N QY  LK
Sbjct: 2110 KKGTDALANKQLELDKVNKQYEKLK 2134



 Score =  137 bits (344), Expect = 4e-30
 Identities = 236/1195 (19%), Positives = 479/1195 (39%), Gaps = 109/1195 (9%)

Query: 471  VEENKTLHELNFSSTRSLKKQQMEISKLKEIKEKLEREFHTSTEESNVLQRETHQIKD-- 528
            V+    L   NF      K +++E     ++K+KL  E        N L   T +I +  
Sbjct: 860  VKARPMLKRRNFEEEGKKKDKEIE-----DLKKKLAEEIKKREAAENALASATAKIGELE 914

Query: 529  -DIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETCKKEHSEKEALREKSK 587
              IQ L ++   +  +L +  L+       + +L+ +   LKET  K   + +  + K +
Sbjct: 915  AKIQDLEDKISELESKLSAAELDKQELNLKIENLEEDKEELKETIDKLKGDLKDSKLKGE 974

Query: 588  DMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQEEKSILADEKSTLLSQLQI 647
            D+ + + E          LN +++ L  TV +  +    +QE      DE + L   +++
Sbjct: 975  DLEDEITE----------LNSQINTLNATVDKKDKTIAEMQESIDEKEDEITKLKGDIKL 1024

Query: 648  ITESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCKLLNDEKNNLQNERSMLISQ 707
            + E    + ++   +  +  D   +   + I+  D +D    L  E  + +N+   L ++
Sbjct: 1025 LEEEKDDLEQDRADVSATKDDIAKKLNKITIECEDAKDEIAKLEQELEDEENKNKDLTNE 1084

Query: 708  LEIVEEKLSNLEKKVTN--LEEKYADVEKDKESAVNQVEELFASILVQKENHSNHKHSS- 764
            L+  + KL   EK +       K A  E+D  S   + E+L    L + +     K S  
Sbjct: 1085 LQQTQLKLGETEKSLAAQVAATKKASDERDTLSQNLENEKLTTKNLTKTKADLEKKISGL 1144

Query: 765  EARLANLENIVRVLQEEQRLGKVEFEQELDRVVNAQIEMFILQNCIEELELKNFVLLTEC 824
            +    +LE+    ++ + R  + + ++  D +         LQ   EE E +   +  E 
Sbjct: 1145 KQDYEDLEDDKNKIEGDLRNAQRKIKELDDEITKGADVSQYLQKQKEEYESQIAKMQEEK 1204

Query: 825  EKLVEASKFSDKVISE--LESENLMQLIEE-EFLLHRIRKFKMDIHKVCGVLQIDSDG-- 879
            E +    K  +K I E  LE ++L + ++E E       K K +I K    LQ + +   
Sbjct: 1205 EAIGNDVKNKEKTIKEKELEIQSLQEKLDETEVEKEDAEKKKKEIEKEMKALQEEKENVE 1264

Query: 880  GGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVENSVLLGSLQQHQSEGEK--- 936
               N  +K++    ++ D ++  +  L     +N++L  +   L   L + Q   EK   
Sbjct: 1265 SSKNSTEKDK---KKLEDNLKDTQKKLDDMTADNEKLKAKAKDLEAQLNEVQDNHEKAVA 1321

Query: 937  ----LKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLRIEVVNGVEKENRSKSTLAA 992
                L  +K   ++E  +++ +   L K K  +  +N+    E     E+ +++   L  
Sbjct: 1322 DAELLNKKKAQSDKELNSLKAELEALTKAKSVVESKNKDSENEKAALSEEIDQANEKLKN 1381

Query: 993  LQAEM----IELRQTNQVFQE---ENGKMLDEKNSLCRNVSDLK--DAKSSAEDEN--SV 1041
            +QA++     +L++ N+   E   +  K++ +   + + + ++K  D +++ + EN   V
Sbjct: 1382 IQADLRKATADLQEANEKKAEVEAQRDKLVADNKKMTKTLEEIKARDEENTYKVENYEKV 1441

Query: 1042 MFHDVLALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLRKNFEVK--- 1098
            +      L   N   +I   + M +++ + +  G L    + LN         F  K   
Sbjct: 1442 LKRKEADLEEANENLDIEKKDRMNKEKQVKKLEGELKETKDKLNAAIAEKDSIFTAKKQS 1501

Query: 1099 EAENVYLNESIERMDKELLEMDKRLKAAETSNAEFSRHIEELKMEQEESTKIKENLDRQI 1158
            +A+   LN+++E  D+ + +++ ++      N      + EL+ + ++  K    L+ Q+
Sbjct: 1502 DADLEELNKTVEEHDEVVAKLNTQITKLTRDNQSAEEELNELRSKADKDKKKISELEEQV 1561

Query: 1159 LEQSE------NCMNHKKEIEHLNEANETLQFEMKTLLHEVEQHRVRE-EALNLELLNK- 1210
             E         N   ++ +I     A+     EMK   +   Q   +E +A N +L +K 
Sbjct: 1562 NELESRPVGTGNADENEIKIRDAQIADLNKALEMKGDQNNQLQATNKELKAKNNDLTSKI 1621

Query: 1211 ---ENEFKLWENEAAAFYHD-------LQMSSICLALLESKVSELTGVCKILDDESSAKS 1260
               ENE K  EN       D       +   +I    LE +V +LT   + L  + +A S
Sbjct: 1622 EITENEMKKLENAKKRLEQDKDEADKAVSEQTIKRKGLEEEVKKLTTEIQALKFQINAPS 1681

Query: 1261 L---ENEHMREIISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLE--------HISLLWT 1309
                E E  R     LES+I  LKEQL       ++ + +   ++        ++  +  
Sbjct: 1682 SVAQEEEKQR-----LESDIAELKEQLEQERTTAANAEAERKKIQAELDEVKFNLEDVTN 1736

Query: 1310 KRNSVVGNGAQKDVVIETCLRKHSHQSARENEIVLIPDGVSDLLTLQTRIRAVEKIMMEE 1369
            +R  +V   ++ D  I++   +   + A E+EI  I D  + L      +      +++ 
Sbjct: 1737 QREKLVAKNSENDAEIDSLKEE---KKALEDEIEKITDDNNKLNEEIDSLDRKYNALLDS 1793

Query: 1370 LKRRVKQKSLTTESTPYSSLEIATYPKVENRKKEIELVEENVFDRNSWRKKPKIRLLMKD 1429
                V  K    +    +   + T  K  N  + + L  +   ++ +   + ++  L K+
Sbjct: 1794 KDSDVSMKEKFQDELKVTKDALETEKK--NHAETMRL--KGRLEKEAAEVQVRLEALQKN 1849

Query: 1430 IPL----------DRNVDDQNSKYLKREHRRTNDHVLELCENNEHEPLSAPTVDH---AM 1476
            + L          D    D   K L  E     D + +  ++   +     T+D     +
Sbjct: 1850 LDLAQQEKAKATKDYRAADGELKSLMNELDDVKDQLDKAQDDLADKEDELATLDQKYKTL 1909

Query: 1477 ICHRSDDSGRYLNYSSELDIEKELGVDKLELSKSVKEKT----EDDKRRILERLSSDGQK 1532
            +  +S    R      +LD+EK  G  K +  K   EK     +++     E   +  ++
Sbjct: 1910 VKQKSVFDSRIQEMQEQLDLEKA-GRAKAQKQKQAYEKKLQELQENDNDFEEYKETADKR 1968

Query: 1533 LAILKMALQDLKKKTETKKKSKQGNDIEYETVKRHIEEVEEAVMQQVSINDQMAK 1587
            +  L     DL+K+ E ++  KQ ++ E + ++   +E+E  V +    N  +AK
Sbjct: 1969 INTLSAQKDDLQKELEKERGLKQDSEKEVQRLRVKCQELETKVAEVGGANVSIAK 2023



 Score =  127 bits (320), Expect = 2e-27
 Identities = 223/1076 (20%), Positives = 439/1076 (40%), Gaps = 136/1076 (12%)

Query: 561  LQNENFMLKETCKKEHSEKEALREKSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEI 620
            L+  NF  +E  KK+  E E L++K   + E + +    E +L     ++  L   ++++
Sbjct: 866  LKRRNF--EEEGKKKDKEIEDLKKK---LAEEIKKREAAENALASATAKIGELEAKIQDL 920

Query: 621  QQFCQVLQEEKSILADEKSTLLSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKS 680
            +     L+ + S    +K  L  +++ + E  +++ E    L+  L D+K++ E L  + 
Sbjct: 921  EDKISELESKLSAAELDKQELNLKIENLEEDKEELKETIDKLKGDLKDSKLKGEDLEDEI 980

Query: 681  GDLEDCCKLLNDEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAV 740
             +L      LN   +      + +   ++  E++++ L+  +  LEE+  D+E+D+    
Sbjct: 981  TELNSQINTLNATVDKKDKTIAEMQESIDEKEDEITKLKGDIKLLEEEKDDLEQDR---- 1036

Query: 741  NQVEELFASILVQKENHSNHKHSSEARLANLENIVRVLQEEQRLGKVEFEQELDRVVNAQ 800
                   A +   K++           +A   N + +  E+ +    + EQEL+   N  
Sbjct: 1037 -------ADVSATKDD-----------IAKKLNKITIECEDAKDEIAKLEQELEDEENKN 1078

Query: 801  IEMFILQNCIEELELKNFVLLTECEKLVEASKFSDKVISELESENLMQLIEEEFLLHR-I 859
             +   L N +++ +LK    L E EK + A   + K  S+ E + L Q +E E L  + +
Sbjct: 1079 KD---LTNELQQTQLK----LGETEKSLAAQVAATKKASD-ERDTLSQNLENEKLTTKNL 1130

Query: 860  RKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEENQQLLVE 919
             K K D+ K    L+ D +   D++  K E  +     KI+ L+  + K  + +Q L  +
Sbjct: 1131 TKTKADLEKKISGLKQDYEDLEDDK-NKIEGDLRNAQRKIKELDDEITKGADVSQYLQKQ 1189

Query: 920  NSVLLGSLQQHQSE----GEKLKLEKKTV---EQEFENMREQNVILQKDKVELLEENRQL 972
                   + + Q E    G  +K ++KT+   E E ++++E+    + +K +  ++ +++
Sbjct: 1190 KEEYESQIAKMQEEKEAIGNDVKNKEKTIKEKELEIQSLQEKLDETEVEKEDAEKKKKEI 1249

Query: 973  RIEVVNGVEKENRSKSTLAALQAEMIELRQTNQVFQEENGKMLDEKNSLCRNVSDLKDAK 1032
              E+    E++   +S+  + + +  +L    +  Q++   M  +   L     DL+   
Sbjct: 1250 EKEMKALQEEKENVESSKNSTEKDKKKLEDNLKDTQKKLDDMTADNEKLKAKAKDLEAQL 1309

Query: 1033 SSAEDENSVMFHDVLALSNLNLVYEIFFTENMVEKRALCEHLGNLSHLNNDLNQEFGVLR 1092
            +  +D +     D   L+      +        E  AL +    +   N D   E   L 
Sbjct: 1310 NEVQDNHEKAVADAELLNKKKAQSDKELNSLKAELEALTKAKSVVESKNKDSENEKAALS 1369

Query: 1093 KNFEVKEAENVYLNESIERMDKELLEMDKRLKAAETSNAEFSRHIEELKMEQEESTKIKE 1152
            +  E+ +A     NE ++ +  +L +    L+ A    AE     ++L  + ++ TK  E
Sbjct: 1370 E--EIDQA-----NEKLKNIQADLRKATADLQEANEKKAEVEAQRDKLVADNKKMTKTLE 1422

Query: 1153 NLDRQILEQSENCMNHKKEIEH----LNEANETLQFEMKTLLHEVEQHRVREEALNLELL 1208
             +  +  E +    N++K ++     L EANE L  E K  +++ +Q     + L  EL 
Sbjct: 1423 EIKARDEENTYKVENYEKVLKRKEADLEEANENLDIEKKDRMNKEKQ----VKKLEGELK 1478

Query: 1209 NKENEFKLWENEAAAFYHDLQMSSICLALLESKVSELTGVCKILDDESSAKSLENEHMRE 1268
              +++      E  + +   + S   L  L   V E   V   L+ + +  + +N+   E
Sbjct: 1479 ETKDKLNAAIAEKDSIFTAKKQSDADLEELNKTVEEHDEVVAKLNTQITKLTRDNQSAEE 1538

Query: 1269 IISLLESEIGGLKEQLSAYVPLVSSLKEDFNSLEHISLLWTKRNSVVGNGAQKDVVIETC 1328
             ++ L S+    K++       +S L+E  N LE         +  VG G          
Sbjct: 1539 ELNELRSKADKDKKK-------ISELEEQVNELE---------SRPVGTG---------- 1572

Query: 1329 LRKHSHQSARENEIVLIPDGVSDL-LTLQTRIRAVEKIMMEELKRRVKQKSLTTESTPYS 1387
                   +A ENEI +    ++DL   L+ +     ++     + + K   LT      S
Sbjct: 1573 -------NADENEIKIRDAQIADLNKALEMKGDQNNQLQATNKELKAKNNDLT------S 1619

Query: 1388 SLEIA--TYPKVENRKKEIE--------LVEENVFDRNSWRKKPKIRLLMKDIPLDRNVD 1437
             +EI      K+EN KK +E         V E    R    ++ K +L  +   L   ++
Sbjct: 1620 KIEITENEMKKLENAKKRLEQDKDEADKAVSEQTIKRKGLEEEVK-KLTTEIQALKFQIN 1678

Query: 1438 DQNSKYLKREHRRTNDHVLELCENNEHEPLSAPTVD------HAMICHRSDDSGRYLNYS 1491
              +S   + E +R    + EL E  E E  +A   +       A +     +     N  
Sbjct: 1679 APSSVAQEEEKQRLESDIAELKEQLEQERTTAANAEAERKKIQAELDEVKFNLEDVTNQR 1738

Query: 1492 SEL---DIEKELGVDKLELSKSVK----EKTEDDKRRILERLSSDGQKLAIL-------- 1536
             +L   + E +  +D L+  K       EK  DD  ++ E + S  +K   L        
Sbjct: 1739 EKLVAKNSENDAEIDSLKEEKKALEDEIEKITDDNNKLNEEIDSLDRKYNALLDSKDSDV 1798

Query: 1537 --KMALQDLKKKTETKKKSKQGNDIEYETVKRHIEEVEEAVMQQVSINDQMAKNVE 1590
              K   QD  K T+   ++++ N  E   +K  +E  +EA   QV + + + KN++
Sbjct: 1799 SMKEKFQDELKVTKDALETEKKNHAETMRLKGRLE--KEAAEVQVRL-EALQKNLD 1851



 Score =  125 bits (314), Expect = 1e-26
 Identities = 224/1175 (19%), Positives = 468/1175 (39%), Gaps = 180/1175 (15%)

Query: 24   KNSKWLLENLTDID------TKVKSMIKLIEEEADSFAR-RAEMYYKK---RPELMKLVE 73
            K  K + E    ID      TK+K  IKL+EEE D   + RA++   K     +L K+  
Sbjct: 996  KKDKTIAEMQESIDEKEDEITKLKGDIKLLEEEKDDLEQDRADVSATKDDIAKKLNKITI 1055

Query: 74   EFYRAYRALAERYDHAMGELRHAHKTMPEAFPNSAYYILNDDSPCGSLGPDAESHTSARP 133
            E   A   +A + +  + +  + +K +      +             LG   +S  +   
Sbjct: 1056 ECEDAKDEIA-KLEQELEDEENKNKDLTNELQQTQL----------KLGETEKSLAAQVA 1104

Query: 134  THRSKKNERSSEESNGE-----VQTLREALAKMQSDKDALFLQYQESLENLSKMETDLNK 188
              +   +ER +   N E      + L +  A ++     L   Y++  ++ +K+E DL  
Sbjct: 1105 ATKKASDERDTLSQNLENEKLTTKNLTKTKADLEKKISGLKQDYEDLEDDKNKIEGDLRN 1164

Query: 189  AQNNARGLDDRASEA-------EIQVEILKESLMQLKADKDA-GEVLYNQCLETIARLES 240
            AQ   + LDD  ++        + Q E  +  + +++ +K+A G  + N+        E 
Sbjct: 1165 AQRKIKELDDEITKGADVSQYLQKQKEEYESQIAKMQEEKEAIGNDVKNK--------EK 1216

Query: 241  MLSQKDNIEAKNLKQELTRVVVQKDTVLLQYKQCLEKIPMLENKIALAEENSRMLNDQIE 300
             + +K+ +E ++L+++L    V+K+    + K+       +E ++   +E    +     
Sbjct: 1217 TIKEKE-LEIQSLQEKLDETEVEKEDAEKKKKE-------IEKEMKALQEEKENVESSKN 1268

Query: 301  RTELEVETLRKNLAEMNEERDSLSVLYHHCLEKISKMENEILHVQENAE------QLKNK 354
             TE + + L  NL +  ++ D ++        K   +E ++  VQ+N E      +L NK
Sbjct: 1269 STEKDKKKLEDNLKDTQKKLDDMTADNEKLKAKAKDLEAQLNEVQDNHEKAVADAELLNK 1328

Query: 355  IEKEAEK--------LEISEKHRGMLEKSNQNLQLEAENLVQRIASKDHELL-------- 398
             + +++K        LE   K + ++E  N++ + E   L + I   + +L         
Sbjct: 1329 KKAQSDKELNSLKAELEALTKAKSVVESKNKDSENEKAALSEEIDQANEKLKNIQADLRK 1388

Query: 399  ---------EKHTEIE---------------RLQTLMHGEHSNFIQIESALQALQKLYSQ 434
                     EK  E+E                L+ +   +  N  ++E+  + L++  + 
Sbjct: 1389 ATADLQEANEKKAEVEAQRDKLVADNKKMTKTLEEIKARDEENTYKVENYEKVLKRKEAD 1448

Query: 435  SQKEQRNLALELKYGL---LLLKDLELSKQDFKEEMQGIVEE------------------ 473
             ++   NL +E K  +     +K LE   ++ K+++   + E                  
Sbjct: 1449 LEEANENLDIEKKDRMNKEKQVKKLEGELKETKDKLNAAIAEKDSIFTAKKQSDADLEEL 1508

Query: 474  NKTLHE-------LNFSSTRSLKKQQMEISKLKEIKEKLEREFHTSTE-ESNVLQRETH- 524
            NKT+ E       LN   T+  +  Q    +L E++ K +++    +E E  V + E+  
Sbjct: 1509 NKTVEEHDEVVAKLNTQITKLTRDNQSAEEELNELRSKADKDKKKISELEEQVNELESRP 1568

Query: 525  -----------QIKD-DIQHLNERYQAMLEQLQSLGLNPNSFAASVRDLQNENFMLKETC 572
                       +I+D  I  LN+  +   +Q   L        A   DL ++  + +   
Sbjct: 1569 VGTGNADENEIKIRDAQIADLNKALEMKGDQNNQLQATNKELKAKNNDLTSKIEITENEM 1628

Query: 573  KKEHSEKEALR----EKSKDMNEVLMENACMEFSLLGLNDELDGLRGTVKEIQQFCQVLQ 628
            KK  + K+ L     E  K ++E  ++   +E  +  L  E+  L+  +       Q  +
Sbjct: 1629 KKLENAKKRLEQDKDEADKAVSEQTIKRKGLEEEVKKLTTEIQALKFQINAPSSVAQ--E 1686

Query: 629  EEKSILADEKSTLLSQLQIITESMQKILENNTVLEKSLSDAKIEFEGLRIKSGDLEDCCK 688
            EEK  L  + + L  QL+    +          ++  L + K   E +  +   L     
Sbjct: 1687 EEKQRLESDIAELKEQLEQERTTAANAEAERKKIQAELDEVKFNLEDVTNQREKLVAKNS 1746

Query: 689  LLNDEKNNLQNERSMLISQLEIVEEKLSNLEKKVTNLEEKYADVEKDKESAVNQVEELFA 748
              + E ++L+ E+  L  ++E + +  + L +++ +L+ KY  +   K+S V+  E+   
Sbjct: 1747 ENDAEIDSLKEEKKALEDEIEKITDDNNKLNEEIDSLDRKYNALLDSKDSDVSMKEKFQD 1806

Query: 749  SILV-------QKENHSNH---KHSSEARLANLENIVRVLQEEQRLGKVEFEQELDRVVN 798
             + V       +K+NH+     K   E   A ++  +  LQ+   L + E  +       
Sbjct: 1807 ELKVTKDALETEKKNHAETMRLKGRLEKEAAEVQVRLEALQKNLDLAQQEKAKATKDYRA 1866

Query: 799  AQIEMFILQNCIEEL-----ELKNFVLLTECEKLVEASKFSDKVISELESENLMQLIEEE 853
            A  E+  L N ++++     + ++ +   E E      K+   V  +   ++ +Q ++E+
Sbjct: 1867 ADGELKSLMNELDDVKDQLDKAQDDLADKEDELATLDQKYKTLVKQKSVFDSRIQEMQEQ 1926

Query: 854  FLLHRIRKFKMDIHKVCGVLQIDSDGGGDNEIKKEEIPISRILDKIESLESSLVKSQEEN 913
              L +  + K    K     ++      DN+ ++ +    + ++ + + +  L K  E+ 
Sbjct: 1927 LDLEKAGRAKAQKQKQAYEKKLQELQENDNDFEEYKETADKRINTLSAQKDDLQKELEKE 1986

Query: 914  QQLLVENSVLLGSLQQHQSEGEKLKLEKKTVEQEFENMREQNVILQKDKVELLEENRQLR 973
            +          G  Q  + E ++L+++ + +E +   +   NV + K K +   E  +L 
Sbjct: 1987 R----------GLKQDSEKEVQRLRVKCQELETKVAEVGGANVSIAKVKAKYEAEIEELT 2036

Query: 974  IEVVNGVEKENRSKSTLAALQAEMIELRQT-------NQVFQEENGKMLDEKNSLCRNVS 1026
             E  + ++ + +++      Q ++ EL++T          F  + GK   E     + V 
Sbjct: 2037 TEAEDALKAKMKAEKKAKTSQKKLDELQKTIADYETKEASFNTQIGKTQAELKKYQQQVR 2096

Query: 1027 DLKDAKSSAEDE----NSVMFHDVLALSNLNLVYE 1057
            D +   SS EDE       + +  L L  +N  YE
Sbjct: 2097 DDETRMSSLEDEIKKGTDALANKQLELDKVNKQYE 2131


  Database: uniref100
    Posted date:  Jan 5, 2005  1:24 AM
  Number of letters in database: 848,049,833
  Number of sequences in database:  2,790,947
  
Lambda     K      H
   0.310    0.128    0.336 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,491,651,614
Number of Sequences: 2790947
Number of extensions: 106650895
Number of successful extensions: 781490
Number of sequences better than 10.0: 19400
Number of HSP's better than 10.0 without gapping: 2526
Number of HSP's successfully gapped in prelim test: 17307
Number of HSP's that attempted gapping in prelim test: 523869
Number of HSP's gapped (non-prelim): 119069
length of query: 1662
length of database: 848,049,833
effective HSP length: 141
effective length of query: 1521
effective length of database: 454,526,306
effective search space: 691334511426
effective search space used: 691334511426
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 82 (36.2 bits)


Medicago: description of AC135320.2