BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC127429.13 - phase: 0 /pseudo
(1603 letters)
Database: uniref100
2,790,947 sequences; 848,049,833 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef100_O65531 Hypothetical protein F4D11.100 [Arabidopsis tha... 1779 0.0
UniRef100_UPI0000362671 UPI0000362671 UniRef100 entry 503 e-140
UniRef100_UPI00002F9784 UPI00002F9784 UniRef100 entry 499 e-139
UniRef100_Q6VMB5 DNA polymerase theta [Homo sapiens] 490 e-136
UniRef100_UPI0000362672 UPI0000362672 UniRef100 entry 489 e-136
UniRef100_UPI00003A9B23 UPI00003A9B23 UniRef100 entry 487 e-135
UniRef100_UPI00003A9B21 UPI00003A9B21 UniRef100 entry 487 e-135
UniRef100_Q80XB7 DNA polymerase theta [Mus musculus] 486 e-135
UniRef100_Q7TQC0 DNA polymerase Q [Mus musculus] 486 e-135
UniRef100_Q96SE4 DNA polymerase theta [Homo sapiens] 484 e-134
UniRef100_Q6ZM94 Novel protein similar to humna DNA-directed pol... 476 e-132
UniRef100_UPI00003A9B24 UPI00003A9B24 UniRef100 entry 462 e-128
UniRef100_Q5TX00 ENSANGP00000027910 [Anopheles gambiae str. PEST] 446 e-123
UniRef100_Q7PT13 ENSANGP00000019077 [Anopheles gambiae str. PEST] 446 e-123
UniRef100_O18475 CG6019-PA [Drosophila melanogaster] 422 e-116
UniRef100_Q8TDG4 DNA helicase HEL308 [Homo sapiens] 360 3e-97
UniRef100_UPI0000437A8D UPI0000437A8D UniRef100 entry 358 7e-97
UniRef100_UPI00001D076D UPI00001D076D UniRef100 entry 301 1e-79
UniRef100_UPI00001802CC UPI00001802CC UniRef100 entry 289 6e-76
UniRef100_Q8R4K9 DNA helicase HEL308 [Mus musculus] 285 6e-75
>UniRef100_O65531 Hypothetical protein F4D11.100 [Arabidopsis thaliana]
Length = 1548
Score = 1779 bits (4607), Expect = 0.0
Identities = 977/1623 (60%), Positives = 1157/1623 (71%), Gaps = 171/1623 (10%)
Query: 1 MAILVLPYVSICTEK----------AEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAV 50
MA+LVLPYVSIC EK AEHLE LLEPLGKHVRSYYGNQGGG+LPKDTSVAV
Sbjct: 1 MALLVLPYVSICAEKVSVVSPSILHAEHLEVLLEPLGKHVRSYYGNQGGGTLPKDTSVAV 60
Query: 51 CTIEKANSLINRLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKS 110
CTIEKANSLINRLLEEGRLSE+GIIVIDELHMVGD RGYLLELMLTKLRYAAGEG S+S
Sbjct: 61 CTIEKANSLINRLLEEGRLSELGIIVIDELHMVGDQHRGYLLELMLTKLRYAAGEGSSES 120
Query: 111 SDGEGSGGSSDKNDPAQGLQIVGMSATMPNVAAVADWLQ-----------AALYQTEFRP 159
S GE SG SS K DPA GLQIVGMSATMPNV AVADWLQ AALYQTEFRP
Sbjct: 121 SSGESSGTSSGKADPAHGLQIVGMSATMPNVGAVADWLQVSKTNHNLCVYAALYQTEFRP 180
Query: 160 VPLEEYIKVGNSIYNKSMELSRTIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRK 219
VPLEEYIKVG++IYNK ME+ RTIPK AD+GGKDPDH+VELCNEVVQEG SVLIFCSSRK
Sbjct: 181 VPLEEYIKVGSTIYNKKMEVVRTIPKAADMGGKDPDHIVELCNEVVQEGNSVLIFCSSRK 240
Query: 220 GCESTARHVAKFLKSFTVDINENNCEFADITSAINSLRKCPAGLDPVLEETFPAGVAFHH 279
GCESTARH++K +K+ V+++ N EF DI SAI++LR+ P+G+DPVLEET P+GVA+HH
Sbjct: 241 GCESTARHISKLIKNVPVNVDGENSEFMDIRSAIDALRRSPSGVDPVLEETLPSGVAYHH 300
Query: 280 AGLTVEEREIVETCYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQM 339
AGLTVEEREIVETCYRKGL+RVLTATSTLAAGVNLPARRVIFRQP IG DFIDGTRY QM
Sbjct: 301 AGLTVEEREIVETCYRKGLVRVLTATSTLAAGVNLPARRVIFRQPMIGRDFIDGTRYKQM 360
Query: 340 AGRAGRTGIDTKGESVLICKPQELKKVMGLLNESCPPLHSCLSEDLNGMTHAILEVVAGG 399
+GRAGRTGIDTKG+SVLICKP ELK++M LLNE+CPPL SCLSED NGMTHAILEVVAGG
Sbjct: 361 SGRAGRTGIDTKGDSVLICKPGELKRIMALLNETCPPLQSCLSEDKNGMTHAILEVVAGG 420
Query: 400 IVQTANDIH---RKFLEWNEDTKLYSTTPLGRASFGSSLCPEESLIVLADLSRAREGFVL 456
IVQTA DIH RKFLEWNE+TKLY+TTPLGR SFGSSLCPEESLIVL DL RAREG V+
Sbjct: 421 IVQTAKDIHRYVRKFLEWNEETKLYTTTPLGRGSFGSSLCPEESLIVLDDLLRAREGLVM 480
Query: 457 ASDLHLVYLVTPINVDVEPDWESYYERFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGS 516
ASDLHLVYLVTPINV VEP+WE YYERF++LSPL+QSVGNRVGV EPFLMRMAHG + +
Sbjct: 481 ASDLHLVYLVTPINVGVEPNWELYYERFMELSPLEQSVGNRVGVVEPFLMRMAHGATVRT 540
Query: 517 -----NKSRWSNNKRQNQHGMSSGIVNSDDQTLRVCKRFYVALILSLLVQETPVGEVCEA 571
+ + + ++HG +S + SD+Q LRVCKRF+VALILS LVQE V EVCEA
Sbjct: 541 LNRPQDVKKNLRGEYDSRHGSTSMKMLSDEQMLRVCKRFFVALILSKLVQEASVTEVCEA 600
Query: 572 FKVARGMVQGLQENAGRFASMVAVFCERLGWHDFEGLVAKFQNRVSFGVRAEVVELTTIP 631
FKVARGMVQ LQENAGRF+SMV+VFCERLGWHD EGLVAKFQNRVSFGVRAE+VELT+IP
Sbjct: 601 FKVARGMVQALQENAGRFSSMVSVFCERLGWHDLEGLVAKFQNRVSFGVRAEIVELTSIP 660
Query: 632 YVKGSRARALYKAGLRTPLAIAEASIPELVKALFESSSWGTEGSAQRSLQFGVAKKIKNG 691
Y+KGSRARALYKAGLRT AIAEASIPE+VKALFESS+W EG+ QR + G+AKKIKNG
Sbjct: 661 YIKGSRARALYKAGLRTSQAIAEASIPEIVKALFESSAWAAEGTGQRRIHLGLAKKIKNG 720
Query: 692 ARKIVLDKAEEARIAAFSAFKSLGYDVPQFAPPISTAVCNSIR----KEVGSSSGSDTAD 747
ARKIVL+KAEEAR AAFSAFKSLG DV + + P+ A +S+ E S GS D
Sbjct: 721 ARKIVLEKAEEARAAAFSAFKSLGLDVNELSKPLPLAPASSLNGQETTERDISRGSVGPD 780
Query: 748 TSHSFIDTNHIDNSNVPA---LEKEKDLIKSSDNGALVSVEGKSDSVMPHSLSTVPVVVP 804
I+ H++ N EK +++ + G VS E S +P+
Sbjct: 781 GLQQSIE-GHMECENFDMDNHREKPSEVLGDATLG--VSSEINLTSRLPN--------FR 829
Query: 805 SINELSMTSGPAKIPDVTTLSVHLQKQNDKSIMHNGCHAQGTGEQDHRGNLASGNMINSS 864
I T+GP+ + +++ + + +++ I Q DH S N +
Sbjct: 830 PIGTAVGTNGPSAVSILSSDTFPIPVYDNREIKPKDNVEQHLTRNDHIP--LSSNKDGTG 887
Query: 865 RKGPINAVSSPGGLDSFLDLWDTVAEFYFDIHYIKRLELHSAAPFEVHGIAICWENSPMY 924
KGP+ A + GG DSFL+LW + EF+FD+HY K +L+S +E+HGIAICW SP+Y
Sbjct: 888 EKGPVTAGNISGGFDSFLELWGSAGEFFFDLHYNKLQDLNSRISYEIHGIAICWNCSPVY 947
Query: 925 YINLPRDILLSGNRKDDGFSLTACSSKQKVSSSNSKQDLMNAMHRWSRISKIIEKKEVRK 984
Y+NL +D+ + A K +V +S++ D++ + RW++ISKI+
Sbjct: 948 YVNLNKDLPNLECVEKQKLIEDAVIGKSEVLASHNMLDVIKS--RWNKISKIMG------ 999
Query: 985 FTWNLKVQIQVLKKPSVSVQRFGSLDTIDKNMHLEVVDNSYILLPPIHVKDAIDMCIVAW 1044
VLK P++S+QR L+ + + + E+VD S++++PP+H IDM IV W
Sbjct: 1000 ---------NVLKSPAISIQRCTRLN-LPEGIRDELVDGSWLMMPPLHTSHTIDMSIVIW 1049
Query: 1045 ILWPDEESSSSPNLDKEVKKRLSPEDAAAANQCGRWRNQMRKAAHNGCCRRVAQTRALCS 1104
ILWPDEE S+PN+DKEVKKRLSPE A AAN+ GRWRNQ+R+ AHNGCCRRVAQTRALCS
Sbjct: 1050 ILWPDEERHSNPNIDKEVKKRLSPEAAEAANRSGRWRNQIRRVAHNGCCRRVAQTRALCS 1109
Query: 1105 VLWKLLVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCIQARKLLVKRLKQLEKEAY 1164
LWK+LVSE+L++AL IE+PLVNVLADMELWGIG+D+EGC++AR +L +L+ LEK+A+
Sbjct: 1110 ALWKILVSEELLQALTTIEMPLVNVLADMELWGIGIDIEGCLRARNILRDKLRSLEKKAF 1169
Query: 1165 KLAGMTFSLSMPADIAKVLFEHLKLPIPDGKNKGKNHPSTGKHCLDALRV---------- 1214
+LAGMTFSL PADIA VLF LKLPIP+ ++KGK HPST KHCLD LR
Sbjct: 1170 ELAGMTFSLHNPADIANVLFGQLKLPIPENQSKGKLHPSTDKHCLDLLRYSEWLIAFPYI 1229
Query: 1215 ------------------------------NARD--------------YFVPTQDNWLLL 1230
N RD +FVPTQ+NWLLL
Sbjct: 1230 AFCFFIIKDNRLFELLSASVEHEVEFKLDKNGRDVSSDADRYKINARDFFVPTQENWLLL 1289
Query: 1231 TADYSQIELRLMAHFSKDSTLIELLRKPDGDVFTMIAARWIGCPEVSVGSRQREQTKKMV 1290
TADYSQIELRLMAHFS+DS+LI L +P+GDVFTMIAA+W G E SV R+QTK+++
Sbjct: 1290 TADYSQIELRLMAHFSRDSSLISKLSQPEGDVFTMIAAKWTGKAEDSVSPHDRDQTKRLI 1349
Query: 1291 YGILYGMGPNSLAEQMDCTSDEASERISNFKSTFPGVASWLHEAVAFCRSKG*G--DLVP 1348
YGILYGMG N LAEQ++CTSDEA E+I +FKS+FP V SWL+E ++FC+ KG G L P
Sbjct: 1350 YGILYGMGANRLAEQLECTSDEAKEKIRSFKSSFPAVTSWLNETISFCQEKGWGCYRLFP 1409
Query: 1349 FLHFVYAFL-LNLNYLWAVCNLIMCKYIHDPDM*RLSREGNDFCQK*NLAVVQKNQKLRG 1407
L + A L + LN+++ YI Q L+G
Sbjct: 1410 LLFVLNAVLCVPLNHIFI--------YI---------------------------QTLKG 1434
Query: 1408 KLSIPFVRCNTLFSFSSKSGYVSLQAVSIHVNIVFLPSTSQGSAADIIKIAMIKIYSEIF 1467
+ F + + QAV+ S QGSAADIIKIAMI IYS I
Sbjct: 1435 RRRF---LSKIKFGNAKEKSKAQRQAVN---------SMCQGSAADIIKIAMINIYSAIA 1482
Query: 1468 PGVDKLDSSSSVTAKFEMLRDRCRILLQVHDELVLEVDPSVVKEAALLLQTSMENAVSLL 1527
VD SSSS +F ML+ RCRILLQVHDELVLEVDPS VK AA+LLQTSMENAVSLL
Sbjct: 1483 EDVDTAASSSSSETRFHMLKGRCRILLQVHDELVLEVDPSYVKLAAMLLQTSMENAVSLL 1542
Query: 1528 GLY 1530
G++
Sbjct: 1543 GMF 1545
>UniRef100_UPI0000362671 UPI0000362671 UniRef100 entry
Length = 2358
Score = 503 bits (1296), Expect = e-140
Identities = 293/710 (41%), Positives = 405/710 (56%), Gaps = 81/710 (11%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+ +LP+VS+ EK +L+ + E G V Y G+ VAVCTIEKANSLIN
Sbjct: 79 ALFILPFVSVAKEKMHYLQSVFEEAGVRVEGYMGSTSAAGGFTSLDVAVCTIEKANSLIN 138
Query: 62 RLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSD 121
RL+EE + +G++V+DELHMVGD RGYLLEL+LTK+ Y A + + + GS
Sbjct: 139 RLIEEDNMGLLGMVVVDELHMVGDSGRGYLLELLLTKICYIAQK--------QNTTGSF- 189
Query: 122 KNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSR 181
+G+QI+GMSAT+PN++ +A WL A LYQT +RPVPL EY+KVG +IY K + + R
Sbjct: 190 ----LEGIQIIGMSATLPNLSLLASWLGAELYQTNYRPVPLHEYLKVGCNIYGKHLSVVR 245
Query: 182 TIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAK----FLKSFTV 237
++ G D DH+V LC E V+EG SVL+FC S+ CE A +A+ S
Sbjct: 246 QFVPALNIKGDD-DHIVSLCYETVREGCSVLLFCPSKNWCEKLADSIAREFYNLRNSGEA 304
Query: 238 DINENNCEFADITSAINSLRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREIVETCYRKG 297
+ + + + LR+ PAGLD +L+ T P GVAFHHAGLT +ER+++E +R+G
Sbjct: 305 EPPPVPLDQEGLVDVVAQLRRTPAGLDSILQRTVPWGVAFHHAGLTFDERDVLEGAFRQG 364
Query: 298 LLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGIDTKGESVLI 357
L+RVL ATSTL++GVNLPARRVI R P +D Y QM+GRAGR G+DT GES+L+
Sbjct: 365 LVRVLAATSTLSSGVNLPARRVIIRTPTFNGHLLDPLTYKQMSGRAGRKGVDTIGESLLV 424
Query: 358 CKPQELKKVMGLLNESCPPLHSCLSED-----LNGMTHAILEVVAGGIVQTANDIH---- 408
CK E + LL S P+ SCL M AILE++ GG+ T D+
Sbjct: 425 CKEVERHNGISLLKGSLQPISSCLVRREGEGVTTSMLRAILEIIVGGVASTPQDVRLYAS 484
Query: 409 ----------------------RKFLEW---NE--------DTKLYSTTPLGRASFGSSL 435
+EW NE + +LY T LG A+ SSL
Sbjct: 485 CSLLAASSKLEELEEVTNKGAIEACVEWLMDNEFISIQKIGEEELYCPTQLGAATLSSSL 544
Query: 436 CPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVD-VEPDWESYYERFVKLSPLDQSV 494
P ESL V ADL RA +GFVL +DLH++YL+TP+ + DW ++ + +LS + V
Sbjct: 545 SPPESLAVFADLQRAMKGFVLENDLHILYLITPLYAEWTTIDWYQFFCLWEQLSSSMKRV 604
Query: 495 GNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNSDDQTLRVCKRFYVAL 554
VGV E FL R G + + + +RQ + V KRF+ L
Sbjct: 605 AELVGVQEGFLARSVSGKLIAKTEKQ----RRQ----------------MAVHKRFFTTL 644
Query: 555 ILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCERLGWHDFEGLVAKFQN 614
+L LV E P+G V + +RG +Q LQ++A +A MV VFC+RLGWH+ E L++++Q
Sbjct: 645 VLHDLVNEVPLGTVASKYSCSRGQLQSLQQSAATYAGMVTVFCKRLGWHNMELLLSQYQT 704
Query: 615 RVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEASIPELVKAL 664
R+SFG++ E+V+L I + RAR LY GL T +A A++ E+ KAL
Sbjct: 705 RLSFGIQRELVDLVRISLLNAPRARTLYAQGLCTVSELARATVAEVEKAL 754
Score = 100 bits (248), Expect = 5e-19
Identities = 62/153 (40%), Positives = 83/153 (53%), Gaps = 9/153 (5%)
Query: 1197 KGKNHPST-------GKHCLDALRVNARDYFVPTQDNWLLLTADYSQIELRLMAHFSKDS 1249
KGKN S G A ++ R FVP ++L ADYSQ+ELR++AH SKD
Sbjct: 2065 KGKNRHSVVPSGAAGGAEQGPAFSISMRLAFVPFSGG-MILAADYSQLELRVLAHLSKDQ 2123
Query: 1250 TLIELLRKPDGDVFTMIAARWIGCPEVSVGSRQREQTKKMVYGILYGMGPNSLAEQMDCT 1309
L+++L DVF IAA W SV R+Q K++ YGI+YGMG SL EQM
Sbjct: 2124 RLLQVLNG-GADVFRCIAAEWKNVDPGSVTDGLRQQAKQICYGIIYGMGAKSLGEQMGVE 2182
Query: 1310 SDEASERISNFKSTFPGVASWLHEAVAFCRSKG 1342
+EA+ I FK+ + G+ ++L E V C G
Sbjct: 2183 ENEAACYIETFKTRYRGINAFLKETVKNCGKNG 2215
Score = 71.6 bits (174), Expect = 2e-10
Identities = 95/406 (23%), Positives = 159/406 (38%), Gaps = 84/406 (20%)
Query: 832 NDKSIMHNGCHAQGTGEQDHRGNLASGNMINSSRKGPINAVSSPGGLDSF-LDLWDTVAE 890
N++SI N HA + Q K P N V SP + F L L V+
Sbjct: 1634 NEQSISMNKGHASPSSPQP---------------KAPSN-VESPVDDEGFTLQLSQDVSL 1677
Query: 891 FYFDIHYIKRLELHSAAPFEVHGIAICWENSPMYYINLPRD------ILLSGNRKDDGFS 944
+ +H + + + + + G+A+CW + YY++L R+ L+ DD +
Sbjct: 1678 SHQRLHGVDGIPVRDSDGLVLVGLAVCWGSRDSYYVSLQREQSTGLSSSLAPPPLDDDLA 1737
Query: 945 LTACSSKQKVSSSNSKQDLMNAMHRWSRISKIIEKKEVRKFTWNLKVQIQVLKKPSVSVQ 1004
L ++K++ ++ +A HR + T+++ + + + S +
Sbjct: 1738 L-----EEKLAQVKTRLGQPSADHRGPVL-----------ITYDI-IHVYKVLVLSCGIS 1780
Query: 1005 RFGSLDTIDKNMHLEVVDNSYILLPPIHVKDAIDMCIVAWILWPDEESSSSPNLDKEVKK 1064
GS + D + W++ P E + PN+
Sbjct: 1781 LEGSCE---------------------------DPKVACWLVDPGSEERTLPNMVTVY-- 1811
Query: 1065 RLSPEDAAAANQCGRWRNQMRKAAHNGCCRRVAQ-----TRALCSVLWKLLVSEKLVEAL 1119
PE+ G +H C R A T A+ S L LL + ++E
Sbjct: 1812 --CPEELTLLGGLGN--------SHTHCPRIRASITSVLTYAVMSHLTGLLQKDGVLEHF 1861
Query: 1120 MEIEIPLVNVLADMELWGIGVDLEGCIQARKLLVKRLKQLEKEAYKLAGMTFSLSMPADI 1179
+E+P LA +EL G+G C + ++++ +L LE EAY LAG +FSL+ D+
Sbjct: 1862 RSVEMPSQVCLALLELNGVGFSTAECERQKQVMQDKLTALESEAYSLAGHSFSLTSIDDV 1921
Query: 1180 AKVLFEHLKLPIPDGKNKGKNHPSTGKHCLDALRVNARDYFVPTQD 1225
A+VLF L LP N K+ + G RV F T+D
Sbjct: 1922 AQVLFLELHLPPNGDVNGPKSKKTLGYGKRGGGRVRLGKQFSTTKD 1967
Score = 41.2 bits (95), Expect = 0.26
Identities = 29/100 (29%), Positives = 48/100 (48%), Gaps = 7/100 (7%)
Query: 1434 VSIHVNIVFLPSTSQGSAADIIKIAMIKIYSEI---FPGVDKLDSSSSV-TAKFEMLRDR 1489
V H + ++ QGSAADI+K+A + I + +P S ++ + +
Sbjct: 2237 VKAHAERQAVNTSVQGSAADIVKLATVNIQKRLRQTYPAAPPSHQHSPTGNSQCRTVTSQ 2296
Query: 1490 CR---ILLQVHDELVLEVDPSVVKEAALLLQTSMENAVSL 1526
R +LQ+HDEL+ E V + A +++ ME AV L
Sbjct: 2297 LRGGYFILQLHDELIYETPEDDVIQVAQIVKREMETAVKL 2336
>UniRef100_UPI00002F9784 UPI00002F9784 UniRef100 entry
Length = 2382
Score = 499 bits (1284), Expect = e-139
Identities = 294/739 (39%), Positives = 412/739 (54%), Gaps = 110/739 (14%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+L+LP+VS+ EK +L+ + E G V Y GN VAVCTIEKANSLIN
Sbjct: 79 ALLILPFVSVAKEKMHYLQSVFEEAGVRVEGYMGNVSAAGGFTSLDVAVCTIEKANSLIN 138
Query: 62 RLLEEGRLSEMG-----------------------IIVIDELHMVGDPKRGYLLELMLTK 98
RL+EE + +G ++V+DELHMVGD RGYLLEL+LTK
Sbjct: 139 RLIEEENMGLLGKNTWFFLTSWCHCDFKSPIFAPGMVVVDELHMVGDSGRGYLLELLLTK 198
Query: 99 LRYAAGEGISKSSDGEGSGGSSDKNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFR 158
+ Y A + + + GS ++G+QI+GMSAT+PN++ +A WL A LYQT++R
Sbjct: 199 ICYIAQK--------QNTAGSL-----SEGIQIIGMSATLPNLSLLASWLCAELYQTDYR 245
Query: 159 PVPLEEYIKVGNSIYNKSMELSRTIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSR 218
PVPL+E++KVG +Y+K + + R ++ G D DH+V LC E V+EG SVL+FC S+
Sbjct: 246 PVPLQEHLKVGCKVYDKDLSVVRQFTPALNVQGDD-DHIVSLCYETVREGCSVLLFCPSK 304
Query: 219 KGCESTARHVAKFLKSFTVDINENNCEFADIT-------SAINSLRKCPAGLDPVLEETF 271
CE A +A+ + + N E ++ + L + PAGLD +L+ T
Sbjct: 305 NWCEKLADSIAREFYNLRNSEHSNEAELPPVSLDQQGLVDVVAQLGRTPAGLDSILQRTV 364
Query: 272 PAGVAFHHAGLTVEEREIVETCYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFI 331
P GVAFHHAGLT +ER+++E +R+GL+RVL ATSTL++GVNLPARRVI R P +
Sbjct: 365 PWGVAFHHAGLTFDERDVLEGAFRQGLVRVLAATSTLSSGVNLPARRVIVRTPTFNGHLL 424
Query: 332 DGTRYMQMAGRAGRTGIDTKGESVLICKPQELKKVMGLLNESCPPLHSCLSED-----LN 386
D Y QM+GRAGR G+DT GES+L+CK E K + LL S P+ SCL
Sbjct: 425 DPLTYKQMSGRAGRKGVDTIGESLLVCKEAERHKGISLLKGSLQPISSCLVRREGEGVTT 484
Query: 387 GMTHAILEVVAGGIVQTANDIH-----------------------------RKFLEW--- 414
M AILE++ GG+ T D+ +EW
Sbjct: 485 SMLRAILEIIVGGVASTPQDVRLYASCSLLAASLKLNMKKELDEETSKGAIEACVEWLMD 544
Query: 415 NE--------DTKLYSTTPLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLV 466
NE + +LY T LG A+ SSL P ESL V ADL RA +GFVL +DLH++YL+
Sbjct: 545 NEFISIQKEGEEELYCPTQLGAATLSSSLSPPESLAVFADLQRAMKGFVLENDLHILYLI 604
Query: 467 TPINVD-VEPDWESYYERFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNK 525
TP+ + DW ++ + +LS + V VGV E FL R G + + + +
Sbjct: 605 TPLYAEWTTIDWYQFFCLWEQLSSSMKRVAELVGVQEGFLARSVSGKIIAKTEKQ----R 660
Query: 526 RQNQHGMSSGIVNSDDQTLRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQEN 585
RQ + V KRF+ L+L LV E P+G V F RG +Q LQ++
Sbjct: 661 RQ----------------MAVHKRFFTTLVLHDLVNEVPLGTVASKFSCNRGQLQSLQQS 704
Query: 586 AGRFASMVAVFCERLGWHDFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAG 645
A +A MV VFC+RLGWH+ E L++++Q R+SFG++ E+V+L + +K +AR LY G
Sbjct: 705 ASTYAGMVTVFCKRLGWHNMELLLSQYQTRLSFGIQRELVDLVRVSLLKALQARTLYAQG 764
Query: 646 LRTPLAIAEASIPELVKAL 664
LRT +A A++ ++ KAL
Sbjct: 765 LRTVAELARATVADVEKAL 783
Score = 101 bits (251), Expect = 2e-19
Identities = 65/164 (39%), Positives = 87/164 (52%), Gaps = 13/164 (7%)
Query: 1190 PIPDGKN----KGKNHPST-------GKHCLDALRVNARDYFVPTQDNWLLLTADYSQIE 1238
P DG++ KGK S G A V+ R FVP ++L ADYSQ+E
Sbjct: 2070 PSQDGRHLAARKGKKRRSAVPSGAAAGSEQGPAFSVSMRHAFVPFSGG-MILAADYSQLE 2128
Query: 1239 LRLMAHFSKDSTLIELLRKPDGDVFTMIAARWIGCPEVSVGSRQREQTKKMVYGILYGMG 1298
LR++AH SKD L+++L DVF IAA W SV R+Q K++ YGI+YGMG
Sbjct: 2129 LRVLAHLSKDQRLLQVLNG-GADVFRCIAAEWKSVDPDSVTDGLRQQAKQICYGIIYGMG 2187
Query: 1299 PNSLAEQMDCTSDEASERISNFKSTFPGVASWLHEAVAFCRSKG 1342
SL EQM ++A+ I FKS + G+ ++L E V C G
Sbjct: 2188 AKSLGEQMGVEENDAACYIETFKSRYRGINAFLKETVKNCGKNG 2231
Score = 64.3 bits (155), Expect = 3e-08
Identities = 50/172 (29%), Positives = 80/172 (46%), Gaps = 18/172 (10%)
Query: 1038 DMCIVAWILWPDEESSSSPNLDKEVKKRLSPEDAAAANQCGRWRNQMRKAAHNGCCRRVA 1097
D + W+L P E + PN+ PE+ G ++H C R A
Sbjct: 1779 DPKVACWLLDPGSEERTLPNMVTVY----CPEELPLLGGLG--------SSHTHCPRVRA 1826
Query: 1098 QTRALCSV-----LWKLLVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCIQARKLL 1152
T ++ + L LL + +++ +E+P LA +EL G+G C + + ++
Sbjct: 1827 STASVLTYAVMGRLTGLLREDGVLDHFRSVEMPSQVCLALLELNGVGFSAAECERQKHVM 1886
Query: 1153 VKRLKQLEKEAYKLAGMTFSLSMPADIAKVLFEHLKLPIPDGKNKGKNHPST 1204
+L LE +AY+LAG +FSL+ D+A+VLF L LP P+G G T
Sbjct: 1887 QAKLAALEGQAYRLAGHSFSLTSVDDVAQVLFLELHLP-PNGDVNGSKSKKT 1937
>UniRef100_Q6VMB5 DNA polymerase theta [Homo sapiens]
Length = 2592
Score = 490 bits (1262), Expect = e-136
Identities = 288/721 (39%), Positives = 410/721 (55%), Gaps = 91/721 (12%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+ +LP+VS+ EK +L+ L + +G V Y G+ +AVCTIE+AN LIN
Sbjct: 140 ALFILPFVSVAKEKKYYLQSLFQEVGIKVDGYMGSTSPSRHFSSLDIAVCTIERANGLIN 199
Query: 62 RLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSD 121
RL+EE ++ +G++V+DELHM+GD RGYLLEL+LTK+ Y + S +D S ++
Sbjct: 200 RLIEENKMDLLGMVVVDELHMLGDSHRGYLLELLLTKICYITRKSASCQADLASSLSNA- 258
Query: 122 KNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSR 181
+QIVGMSAT+PN+ VA WL A LY T+FRPVPL E +KVGNSIY+ SM+L R
Sbjct: 259 -------VQIVGMSATLPNLELVASWLNAELYHTDFRPVPLLESVKVGNSIYDSSMKLVR 311
Query: 182 TIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKFLKSFTVD--- 238
+ G D DHVV LC E + + SVL+FC S+K CE A +A+ +
Sbjct: 312 EFEPMLQVKG-DEDHVVSLCYETICDNHSVLLFCPSKKWCEKLADIIAREFYNLHHQAEG 370
Query: 239 ---INENNC-----EFADITSAINSLRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREIV 290
+ + C E ++ ++ LR+ P+GLD VL++T P GVAFHHAGLT EER+I+
Sbjct: 371 EGLVKPSECPPVILEQKELLEVMDQLRRLPSGLDSVLQKTVPWGVAFHHAGLTFEERDII 430
Query: 291 ETCYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGIDT 350
E +R+GL+RVL ATSTL++GVNLPARRVI R P G +D Y QM GRAGR G+DT
Sbjct: 431 EGAFRQGLIRVLAATSTLSSGVNLPARRVIIRTPIFGGRPLDILTYKQMVGRAGRKGVDT 490
Query: 351 KGESVLICKPQELKKVMGLLNESCPPLHSCL----SEDLNG-MTHAILEVVAGGIVQTAN 405
GES+LICK E K + LL S P+ SCL E++ G M AILE++ GG+ T+
Sbjct: 491 VGESILICKNSEKSKGIALLQGSLKPVRSCLQRREGEEVTGSMIRAILEIIVGGVASTSQ 550
Query: 406 DIH----------------------------------------RKFLEWNE-----DTKL 420
D+H +F++ E + K+
Sbjct: 551 DMHTYAACTFLAASMKEGKQGIQRNQESVQLGAIEACVMWLLENEFIQSTEASDGTEGKV 610
Query: 421 YSTTPLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVD-VEPDWES 479
Y T LG A+ SSL P ++L + ADL RA +GFVL +DLH++YLVTP+ D DW
Sbjct: 611 YHPTHLGSATLSSSLSPADTLDIFADLQRAMKGFVLENDLHILYLVTPMFEDWTTIDWYR 670
Query: 480 YYERFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNS 539
++ + KL + V VGV E FL R G + + + QH
Sbjct: 671 FFCLWEKLPTSMKRVAELVGVEEGFLARCVKGKVVA---------RTERQH--------- 712
Query: 540 DDQTLRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCER 599
+ + + KRF+ +L+L L+ E P+ E+ + + RG +Q LQ++A +A M+ VF R
Sbjct: 713 --RQMAIHKRFFTSLVLLDLISEVPLREINQKYGCNRGQIQSLQQSAAVYAGMITVFSNR 770
Query: 600 LGWHDFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEASIPE 659
LGWH+ E L+++FQ R++FG++ E+ +L + + RAR LY +G T +A A+I E
Sbjct: 771 LGWHNMELLLSQFQKRLTFGIQRELCDLVRVSLLNAQRARVLYASGFHTVADLARANIVE 830
Query: 660 L 660
+
Sbjct: 831 V 831
Score = 99.0 bits (245), Expect = 1e-18
Identities = 60/162 (37%), Positives = 84/162 (51%), Gaps = 11/162 (6%)
Query: 1191 IPDGKNKGKNHPSTGKHCLDALRVNARDYFVPTQDNWL----------LLTADYSQIELR 1240
+P G+ K K S C + A D +P + +L ADYSQ+ELR
Sbjct: 2280 LPMGRGKYKKGFSVNPRCQAQMEERAADRGMPFSISMRHAFVPFPGGSILAADYSQLELR 2339
Query: 1241 LMAHFSKDSTLIELLRKPDGDVFTMIAARWIGCPEVSVGSRQREQTKKMVYGILYGMGPN 1300
++AH S D LI++L DVF IAA W SVG R+Q K++ YGI+YGMG
Sbjct: 2340 ILAHLSHDRRLIQVLNT-GADVFRSIAAEWKMIEPESVGDDLRQQAKQICYGIIYGMGAK 2398
Query: 1301 SLAEQMDCTSDEASERISNFKSTFPGVASWLHEAVAFCRSKG 1342
SL EQM ++A+ I +FKS + G+ ++ E V C+ G
Sbjct: 2399 SLGEQMGIKENDAACYIDSFKSRYTGINQFMTETVKNCKRDG 2440
Score = 61.6 bits (148), Expect = 2e-07
Identities = 52/174 (29%), Positives = 81/174 (45%), Gaps = 11/174 (6%)
Query: 1038 DMCIVAWILWPDEESSSSPNLDKEVKKRLSPE----DAAAANQCGRWRNQMRKAAHNGCC 1093
D + W+L PD S P L V L E + +Q + + H+G
Sbjct: 1990 DPKVACWLLDPD---SQEPTLHSIVTSFLPHELPLLEGMETSQGIQSLGLNAGSEHSGRY 2046
Query: 1094 RRVAQTRAL---CSVLWKLLVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCIQARK 1150
R ++ + + L LL E L + ++E+P LA +EL GIG C +
Sbjct: 2047 RASVESILIFNSMNQLNSLLQKENLQDVFRKVEMPSQYCLALLELNGIGFSTAECESQKH 2106
Query: 1151 LLVKRLKQLEKEAYKLAGMTFSLSMPADIAKVLFEHLKLPIPDGKNKGKNHPST 1204
++ +L +E +AY+LAG +FS + DIA+VLF LKLP P+ + K + T
Sbjct: 2107 IMQAKLDAIETQAYQLAGHSFSFTSSDDIAEVLFLELKLP-PNREMKNQGSKKT 2159
Score = 42.0 bits (97), Expect = 0.15
Identities = 43/159 (27%), Positives = 64/159 (40%), Gaps = 60/159 (37%)
Query: 1448 QGSAADIIKIAMIKIYSEI--FPGVDK--------LDSSSSVTAKFEMLRDR-CRI---- 1492
QGSAADI+KIA + I ++ F K L S + ++ L+ C I
Sbjct: 2476 QGSAADIVKIATVNIQKQLETFHSTFKSHGHREGMLQSDQTGLSRKRKLQGMFCPIRGGF 2535
Query: 1493 -LLQVHDELVLEVDPSVVKEAALLLQTSMENAVSLLGLYSLNKLFFWPFLFGCRHKLVKV 1551
+LQ+HDEL+ EV V + A +++ ME+AV L
Sbjct: 2536 FILQLHDELLYEVAEEDVVQVAQIVKNEMESAVKL------------------------- 2570
Query: 1552 IEDLTVWSNHIFTVYAYASAVPLNVKLKVGRTWGSLEPF 1590
+V L VK+K+G +WG L+ F
Sbjct: 2571 -------------------SVKLKVKVKIGASWGELKDF 2590
>UniRef100_UPI0000362672 UPI0000362672 UniRef100 entry
Length = 2181
Score = 489 bits (1259), Expect = e-136
Identities = 291/720 (40%), Positives = 401/720 (55%), Gaps = 102/720 (14%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+ +LP+VS+ EK +L+ + E G V Y G+ VAVCTIEKANSLIN
Sbjct: 79 ALFILPFVSVAKEKMHYLQSVFEEAGVRVEGYMGSTSAAGGFTSLDVAVCTIEKANSLIN 138
Query: 62 RLLEEGRLSEMG-------------IIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGIS 108
RL+EE + +G ++V+DELHMVGD RGYLLEL+LTK+ Y A +
Sbjct: 139 RLIEEDNMGLLGKNQFLFCYTQCHCMVVVDELHMVGDSGRGYLLELLLTKICYIAQK--- 195
Query: 109 KSSDGEGSGGSSDKNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKV 168
+ + GS +G+QI+GMSAT+PN++ +A WL A LYQT +RPVPL EY+KV
Sbjct: 196 -----QNTTGSF-----LEGIQIIGMSATLPNLSLLASWLGAELYQTNYRPVPLHEYLKV 245
Query: 169 GNSIYNKSMELSRTIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHV 228
G +IY K + + D DH+V LC E V+EG SVL+FC S+ CE A +
Sbjct: 246 GCNIYGKHLSVG------------DDDHIVSLCYETVREGCSVLLFCPSKNWCEKLADSI 293
Query: 229 AK-FLKSFTVDINENNCEFADITSAINSLRKCPAGLDPVLEETFPAGVAFHHAGLTVEER 287
A+ F + + + + LR+ PAGLD +L+ T P GVAFHHAGLT +ER
Sbjct: 294 AREFYNLRNSEPPPVPLDQEGLVDVVAQLRRTPAGLDSILQRTVPWGVAFHHAGLTFDER 353
Query: 288 EIVETCYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTG 347
+++E +R+GL+RVL ATSTL++GVNLPARRVI R P +D Y QM+GRAGR G
Sbjct: 354 DVLEGAFRQGLVRVLAATSTLSSGVNLPARRVIIRTPTFNGHLLDPLTYKQMSGRAGRKG 413
Query: 348 IDTKGESVLICKPQELKKVMGLLNESCPPLHSCLSED-----LNGMTHAILEVVAGGIVQ 402
+DT GES+L+CK E + LL S P+ SCL M AILE++ GG+
Sbjct: 414 VDTIGESLLVCKEVERHNGISLLKGSLQPISSCLVRREGEGVTTSMLRAILEIIVGGVAS 473
Query: 403 TANDIH--------------------------RKFLEW---NE--------DTKLYSTTP 425
T D+ +EW NE + +LY T
Sbjct: 474 TPQDVRLYASCSLLAASSKLEELEEVTNKGAIEACVEWLMDNEFISIQKIGEEELYCPTQ 533
Query: 426 LGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVD-VEPDWESYYERF 484
LG A+ SSL P ESL V ADL RA +GFVL +DLH++YL+TP+ + DW ++ +
Sbjct: 534 LGAATLSSSLSPPESLAVFADLQRAMKGFVLENDLHILYLITPLYAEWTTIDWYQFFCLW 593
Query: 485 VKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNSDDQTL 544
+LS + V VGV E FL R G + + + +RQ +
Sbjct: 594 EQLSSSMKRVAELVGVQEGFLARSVSGKLIAKTEKQ----RRQ----------------M 633
Query: 545 RVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCERLGWHD 604
V KRF+ L+L LV E P+G V + +RG +Q LQ++A +A MV VFC+RLGWH+
Sbjct: 634 AVHKRFFTTLVLHDLVNEVPLGTVASKYSCSRGQLQSLQQSAATYAGMVTVFCKRLGWHN 693
Query: 605 FEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEASIPELVKAL 664
E L++++Q R+SFG++ E+V+L I + RAR LY GL T +A A++ E+ KAL
Sbjct: 694 MELLLSQYQTRLSFGIQRELVDLVRISLLNAPRARTLYAQGLCTVSELARATVAEVEKAL 753
Score = 100 bits (248), Expect = 5e-19
Identities = 62/153 (40%), Positives = 83/153 (53%), Gaps = 9/153 (5%)
Query: 1197 KGKNHPST-------GKHCLDALRVNARDYFVPTQDNWLLLTADYSQIELRLMAHFSKDS 1249
KGKN S G A ++ R FVP ++L ADYSQ+ELR++AH SKD
Sbjct: 1888 KGKNRHSVVPSGAAGGAEQGPAFSISMRLAFVPFSGG-MILAADYSQLELRVLAHLSKDQ 1946
Query: 1250 TLIELLRKPDGDVFTMIAARWIGCPEVSVGSRQREQTKKMVYGILYGMGPNSLAEQMDCT 1309
L+++L DVF IAA W SV R+Q K++ YGI+YGMG SL EQM
Sbjct: 1947 RLLQVLNG-GADVFRCIAAEWKNVDPGSVTDGLRQQAKQICYGIIYGMGAKSLGEQMGVE 2005
Query: 1310 SDEASERISNFKSTFPGVASWLHEAVAFCRSKG 1342
+EA+ I FK+ + G+ ++L E V C G
Sbjct: 2006 ENEAACYIETFKTRYRGINAFLKETVKNCGKNG 2038
Score = 67.8 bits (164), Expect = 3e-09
Identities = 57/193 (29%), Positives = 85/193 (43%), Gaps = 17/193 (8%)
Query: 1038 DMCIVAWILWPDEESSSSPNLDKEVKKRLSPEDAAAANQCGRWRNQMRKAAHNGCCRRVA 1097
D + W++ P E + PN+ PE+ G +H C R A
Sbjct: 1610 DPKVACWLVDPGSEERTLPNMVTVY----CPEELTLLGGLGN--------SHTHCPRIRA 1657
Query: 1098 Q-----TRALCSVLWKLLVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCIQARKLL 1152
T A+ S L LL + ++E +E+P LA +EL G+G C + ++++
Sbjct: 1658 SITSVLTYAVMSHLTGLLQKDGVLEHFRSVEMPSQVCLALLELNGVGFSTAECERQKQVM 1717
Query: 1153 VKRLKQLEKEAYKLAGMTFSLSMPADIAKVLFEHLKLPIPDGKNKGKNHPSTGKHCLDAL 1212
+L LE EAY LAG +FSL+ D+A+VLF L LP N K+ + G
Sbjct: 1718 QDKLTALESEAYSLAGHSFSLTSIDDVAQVLFLELHLPPNGDVNGPKSKKTLGYGKRGGG 1777
Query: 1213 RVNARDYFVPTQD 1225
RV F T+D
Sbjct: 1778 RVRLGKQFSTTKD 1790
Score = 41.2 bits (95), Expect = 0.26
Identities = 29/100 (29%), Positives = 48/100 (48%), Gaps = 7/100 (7%)
Query: 1434 VSIHVNIVFLPSTSQGSAADIIKIAMIKIYSEI---FPGVDKLDSSSSV-TAKFEMLRDR 1489
V H + ++ QGSAADI+K+A + I + +P S ++ + +
Sbjct: 2060 VKAHAERQAVNTSVQGSAADIVKLATVNIQKRLRQTYPAAPPSHQHSPTGNSQCRTVTSQ 2119
Query: 1490 CR---ILLQVHDELVLEVDPSVVKEAALLLQTSMENAVSL 1526
R +LQ+HDEL+ E V + A +++ ME AV L
Sbjct: 2120 LRGGYFILQLHDELIYETPEDDVIQVAQIVKREMETAVKL 2159
>UniRef100_UPI00003A9B23 UPI00003A9B23 UniRef100 entry
Length = 2497
Score = 487 bits (1253), Expect = e-135
Identities = 281/725 (38%), Positives = 402/725 (54%), Gaps = 88/725 (12%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+ +LP+VS+ EK +L+ L + + V Y G+ VAVCTIEKAN LIN
Sbjct: 80 ALFILPFVSVAKEKKCYLQALFQEVDMRVGGYMGSISPAGRFSLLDVAVCTIEKANGLIN 139
Query: 62 RLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSD 121
RL+EE ++ +G++V+DELHM+GD RGYLLEL+LTK+RY + + + + G
Sbjct: 140 RLIEENQMDSLGVVVVDELHMLGDSHRGYLLELLLTKVRYITEKAAKRKTKMKSPGFG-- 197
Query: 122 KNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSR 181
G+Q+VGMSAT+PN+ +A WL A LY T+FRPVPL+E++K+GN+IY+ SM L R
Sbjct: 198 ------GIQVVGMSATLPNLGLLASWLDAELYCTDFRPVPLKEWVKIGNNIYDSSMNLVR 251
Query: 182 TIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAK-FLKSFTVDIN 240
L G D DHVV LC E V +G SVL+FC S+ CE A +A+ F + +
Sbjct: 252 EFQPKLQLKG-DEDHVVSLCYETVCDGHSVLLFCPSKNWCEKLADIIAREFYSLQQAESS 310
Query: 241 ENNCEFADIT-------SAINSLRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREIVETC 293
N + + ++ LR+ +GLD VL+ T P GVAFHHAGLT +ER+I+E
Sbjct: 311 AKNSSLSPVVVDREGIDEVLDQLRRSLSGLDSVLQRTLPWGVAFHHAGLTFDERDIIEGA 370
Query: 294 YRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGIDTKGE 353
+R+ +RVL ATSTL++GVNLPARRVI R P G +D Y QMAGRAGR G+DT+GE
Sbjct: 371 FRQSTIRVLAATSTLSSGVNLPARRVIIRTPMFGGTLLDVLTYKQMAGRAGRKGVDTEGE 430
Query: 354 SVLICKPQELKKVMGLLNESCPPLHSCLSED-----LNGMTHAILEVVAGGIVQTANDIH 408
S+L+CKP E K LL S P+ SCL + M AILE++ G+ T +D+
Sbjct: 431 SILVCKPSERSKGTALLQGSLKPVRSCLLRKEGEGVASSMKRAILEIIVSGVANTPDDVQ 490
Query: 409 R-------------------------------------------KFLEWNED--TKLYST 423
+ LE +D K++
Sbjct: 491 TYASCTLLASSLKDNKRENEKEQDKVQTGPIEACIAWLLENEFIQVLERADDKKAKIFHP 550
Query: 424 TPLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVD-VEPDWESYYE 482
T LG A+ SSL P E++ + +DL RA + FVL +DLH+VYLVTP+ D DW ++
Sbjct: 551 THLGSATLSSSLSPTEAMEIFSDLQRAMKSFVLENDLHIVYLVTPVYEDWTTIDWYQFFC 610
Query: 483 RFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNSDDQ 542
+ KL + V VG+ E FL R G + ++ +
Sbjct: 611 LWEKLPASMKRVAELVGIEEGFLARSVKGKITAKTEKQY--------------------R 650
Query: 543 TLRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCERLGW 602
+ + KRF+ +L L L+ E P+ ++ + + +RG +Q LQ++A +A MV VFC RLGW
Sbjct: 651 QMAIHKRFFTSLALLDLISEVPLKDMTKKYGCSRGQLQSLQQSAATYAGMVTVFCNRLGW 710
Query: 603 HDFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEASIPELVK 662
H+ E L+++FQ+R++FGV E+ +L + + RAR LY AG T +A+AS ++
Sbjct: 711 HNMELLLSQFQSRLTFGVHRELCDLVRVSLLNAQRARMLYNAGFVTVADLAKASPGDVAT 770
Query: 663 ALFES 667
AL S
Sbjct: 771 ALKNS 775
Score = 122 bits (305), Expect = 1e-25
Identities = 114/391 (29%), Positives = 161/391 (41%), Gaps = 132/391 (33%)
Query: 1214 VNARDYFVPTQDNWLLLTADYSQIELRLMAHFSKDSTLIELLRKPDGDVFTMIAARWIGC 1273
V+ R FVP ++L ADY Q+ELR++AHFS+D LIE K DVF IAA W
Sbjct: 2219 VSMRHAFVPFPGGFIL-AADYCQLELRILAHFSRDCRLIEAFNK-GADVFKSIAAEWKMI 2276
Query: 1274 PEVSVGSRQREQTKKMVYGILYGMGPNSLAEQMDCTSDEASERISNFKSTFPGVASWLHE 1333
+VG R+Q K++ YGI+YG+G SL EQM ++A+ I +FKS + G+ +L E
Sbjct: 2277 DSEAVGDSTRQQAKQICYGIIYGIGAKSLGEQMGIDDNKAANYIESFKSRYTGIQKFLKE 2336
Query: 1334 AVAFCRSKG*GDLVPFLHFVYAFLLNLNYLWAVCNLIMCKYIHDPDM*RLSREGNDFCQK 1393
V+ CR G FV L YL A+ R+ N
Sbjct: 2337 TVSNCRRDG---------FVQTILGRRRYLPAI------------------RDSN----- 2364
Query: 1394 *NLAVVQKNQKLRGKLSIPFVRCNTLFSFSSKSGYVSLQAVSIHVNIVFLPSTSQGSAAD 1453
P+++ + QAV+ +T QGSAAD
Sbjct: 2365 ------------------PYIK-----------AHAERQAVN---------TTVQGSAAD 2386
Query: 1454 IIKIAMIKIYS--EIFPGVDK----LDSSSSVTAKFEMLRDRCR----------ILLQVH 1497
I+K A + I E V+K L++S + R R R +LQ+H
Sbjct: 2387 IVKTATVNIQRRLEALSSVNKSHGHLENSFQRDKTGRLSRKRNREMLHPISGGFFILQLH 2446
Query: 1498 DELVLEVDPSVVKEAALLLQTSMENAVSLLGLYSLNKLFFWPFLFGCRHKLVKVIEDLTV 1557
DEL+ EV V + A +++ MENAV L
Sbjct: 2447 DELLYEVAEDDVIQVAQIVKHEMENAVKL------------------------------- 2475
Query: 1558 WSNHIFTVYAYASAVPLNVKLKVGRTWGSLE 1588
+V LNVK+K+G +WG L+
Sbjct: 2476 -------------SVKLNVKVKIGPSWGELQ 2493
Score = 61.2 bits (147), Expect = 2e-07
Identities = 36/105 (34%), Positives = 62/105 (58%), Gaps = 3/105 (2%)
Query: 1089 HNGCCRRVAQTRALCSVLWKL---LVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGC 1145
H+G R ++ + +++ +L L E L + ++E+P LA +EL GIG
Sbjct: 1949 HSGRYRAAIESVLIFNIMNQLHSELRKENLTDVFSKVEMPNHYCLALLELNGIGFSTAAY 2008
Query: 1146 IQARKLLVKRLKQLEKEAYKLAGMTFSLSMPADIAKVLFEHLKLP 1190
++++ +L ++E +AY+LAG +FSL+ P D+A+VLF LKLP
Sbjct: 2009 ETQKQVMQAKLTEIETKAYQLAGHSFSLTSPDDVAEVLFLELKLP 2053
>UniRef100_UPI00003A9B21 UPI00003A9B21 UniRef100 entry
Length = 2608
Score = 487 bits (1253), Expect = e-135
Identities = 281/725 (38%), Positives = 402/725 (54%), Gaps = 88/725 (12%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+ +LP+VS+ EK +L+ L + + V Y G+ VAVCTIEKAN LIN
Sbjct: 145 ALFILPFVSVAKEKKCYLQALFQEVDMRVGGYMGSISPAGRFSLLDVAVCTIEKANGLIN 204
Query: 62 RLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSD 121
RL+EE ++ +G++V+DELHM+GD RGYLLEL+LTK+RY + + + + G
Sbjct: 205 RLIEENQMDSLGVVVVDELHMLGDSHRGYLLELLLTKVRYITEKAAKRKTKMKSPGFG-- 262
Query: 122 KNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSR 181
G+Q+VGMSAT+PN+ +A WL A LY T+FRPVPL+E++K+GN+IY+ SM L R
Sbjct: 263 ------GIQVVGMSATLPNLGLLASWLDAELYCTDFRPVPLKEWVKIGNNIYDSSMNLVR 316
Query: 182 TIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAK-FLKSFTVDIN 240
L G D DHVV LC E V +G SVL+FC S+ CE A +A+ F + +
Sbjct: 317 EFQPKLQLKG-DEDHVVSLCYETVCDGHSVLLFCPSKNWCEKLADIIAREFYSLQQAESS 375
Query: 241 ENNCEFADIT-------SAINSLRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREIVETC 293
N + + ++ LR+ +GLD VL+ T P GVAFHHAGLT +ER+I+E
Sbjct: 376 AKNSSLSPVVVDREGIDEVLDQLRRSLSGLDSVLQRTLPWGVAFHHAGLTFDERDIIEGA 435
Query: 294 YRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGIDTKGE 353
+R+ +RVL ATSTL++GVNLPARRVI R P G +D Y QMAGRAGR G+DT+GE
Sbjct: 436 FRQSTIRVLAATSTLSSGVNLPARRVIIRTPMFGGTLLDVLTYKQMAGRAGRKGVDTEGE 495
Query: 354 SVLICKPQELKKVMGLLNESCPPLHSCLSED-----LNGMTHAILEVVAGGIVQTANDIH 408
S+L+CKP E K LL S P+ SCL + M AILE++ G+ T +D+
Sbjct: 496 SILVCKPSERSKGTALLQGSLKPVRSCLLRKEGEGVASSMKRAILEIIVSGVANTPDDVQ 555
Query: 409 R-------------------------------------------KFLEWNED--TKLYST 423
+ LE +D K++
Sbjct: 556 TYASCTLLASSLKDNKRENEKEQDKVQTGPIEACIAWLLENEFIQVLERADDKKAKIFHP 615
Query: 424 TPLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVD-VEPDWESYYE 482
T LG A+ SSL P E++ + +DL RA + FVL +DLH+VYLVTP+ D DW ++
Sbjct: 616 THLGSATLSSSLSPTEAMEIFSDLQRAMKSFVLENDLHIVYLVTPVYEDWTTIDWYQFFC 675
Query: 483 RFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNSDDQ 542
+ KL + V VG+ E FL R G + ++ +
Sbjct: 676 LWEKLPASMKRVAELVGIEEGFLARSVKGKITAKTEKQY--------------------R 715
Query: 543 TLRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCERLGW 602
+ + KRF+ +L L L+ E P+ ++ + + +RG +Q LQ++A +A MV VFC RLGW
Sbjct: 716 QMAIHKRFFTSLALLDLISEVPLKDMTKKYGCSRGQLQSLQQSAATYAGMVTVFCNRLGW 775
Query: 603 HDFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEASIPELVK 662
H+ E L+++FQ+R++FGV E+ +L + + RAR LY AG T +A+AS ++
Sbjct: 776 HNMELLLSQFQSRLTFGVHRELCDLVRVSLLNAQRARMLYNAGFVTVADLAKASPGDVAT 835
Query: 663 ALFES 667
AL S
Sbjct: 836 ALKNS 840
Score = 122 bits (305), Expect = 1e-25
Identities = 114/391 (29%), Positives = 161/391 (41%), Gaps = 132/391 (33%)
Query: 1214 VNARDYFVPTQDNWLLLTADYSQIELRLMAHFSKDSTLIELLRKPDGDVFTMIAARWIGC 1273
V+ R FVP ++L ADY Q+ELR++AHFS+D LIE K DVF IAA W
Sbjct: 2330 VSMRHAFVPFPGGFIL-AADYCQLELRILAHFSRDCRLIEAFNK-GADVFKSIAAEWKMI 2387
Query: 1274 PEVSVGSRQREQTKKMVYGILYGMGPNSLAEQMDCTSDEASERISNFKSTFPGVASWLHE 1333
+VG R+Q K++ YGI+YG+G SL EQM ++A+ I +FKS + G+ +L E
Sbjct: 2388 DSEAVGDSTRQQAKQICYGIIYGIGAKSLGEQMGIDDNKAANYIESFKSRYTGIQKFLKE 2447
Query: 1334 AVAFCRSKG*GDLVPFLHFVYAFLLNLNYLWAVCNLIMCKYIHDPDM*RLSREGNDFCQK 1393
V+ CR G FV L YL A+ R+ N
Sbjct: 2448 TVSNCRRDG---------FVQTILGRRRYLPAI------------------RDSN----- 2475
Query: 1394 *NLAVVQKNQKLRGKLSIPFVRCNTLFSFSSKSGYVSLQAVSIHVNIVFLPSTSQGSAAD 1453
P+++ + QAV+ +T QGSAAD
Sbjct: 2476 ------------------PYIK-----------AHAERQAVN---------TTVQGSAAD 2497
Query: 1454 IIKIAMIKIYS--EIFPGVDK----LDSSSSVTAKFEMLRDRCR----------ILLQVH 1497
I+K A + I E V+K L++S + R R R +LQ+H
Sbjct: 2498 IVKTATVNIQRRLEALSSVNKSHGHLENSFQRDKTGRLSRKRNREMLHPISGGFFILQLH 2557
Query: 1498 DELVLEVDPSVVKEAALLLQTSMENAVSLLGLYSLNKLFFWPFLFGCRHKLVKVIEDLTV 1557
DEL+ EV V + A +++ MENAV L
Sbjct: 2558 DELLYEVAEDDVIQVAQIVKHEMENAVKL------------------------------- 2586
Query: 1558 WSNHIFTVYAYASAVPLNVKLKVGRTWGSLE 1588
+V LNVK+K+G +WG L+
Sbjct: 2587 -------------SVKLNVKVKIGPSWGELQ 2604
Score = 61.2 bits (147), Expect = 2e-07
Identities = 36/105 (34%), Positives = 62/105 (58%), Gaps = 3/105 (2%)
Query: 1089 HNGCCRRVAQTRALCSVLWKL---LVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGC 1145
H+G R ++ + +++ +L L E L + ++E+P LA +EL GIG
Sbjct: 2058 HSGRYRAAIESVLIFNIMNQLHSELRKENLTDVFSKVEMPNHYCLALLELNGIGFSTAAY 2117
Query: 1146 IQARKLLVKRLKQLEKEAYKLAGMTFSLSMPADIAKVLFEHLKLP 1190
++++ +L ++E +AY+LAG +FSL+ P D+A+VLF LKLP
Sbjct: 2118 ETQKQVMQAKLTEIETKAYQLAGHSFSLTSPDDVAEVLFLELKLP 2162
>UniRef100_Q80XB7 DNA polymerase theta [Mus musculus]
Length = 2544
Score = 486 bits (1250), Expect = e-135
Identities = 287/724 (39%), Positives = 407/724 (55%), Gaps = 87/724 (12%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+ +LP+VS+ EK +L+ L + +G V Y G+ +AVCTIE+AN L+N
Sbjct: 139 ALFILPFVSVAKEKKCYLQSLFQEVGLKVDGYMGSTSPTGQFSSLDIAVCTIERANGLVN 198
Query: 62 RLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSD 121
RL+EE ++ +G++V+DELHM+GD RGYLLEL+LTK+ Y KS+ + S+
Sbjct: 199 RLIEENKMDLLGMVVVDELHMLGDSHRGYLLELLLTKICYVT----RKSASHQAESASTL 254
Query: 122 KNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSR 181
N +QIVGMSAT+PN+ VA WL A LY T+FRPVPL E IK+GNSIY+ SM+L R
Sbjct: 255 SN----AVQIVGMSATLPNLQLVASWLNAELYHTDFRPVPLLESIKIGNSIYDSSMKLVR 310
Query: 182 TIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKFLKSF------ 235
+ G D DH+V LC E +Q+ SVLIFC S+K CE A +A+ +
Sbjct: 311 EFQPLLQVKG-DEDHIVSLCYETIQDNHSVLIFCPSKKWCEKVADIIAREFYNLHHQPEG 369
Query: 236 TVDINENNCEFAD---ITSAINSLRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREIVET 292
V +E D + ++ L++ P+GLD VL+ T P GVAFHHAGLT EER+I+E
Sbjct: 370 LVKSSEFPPVILDQKSLLEVMDQLKRSPSGLDSVLKNTVPWGVAFHHAGLTFEERDIIEG 429
Query: 293 CYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGIDTKG 352
+R+G +RVL ATSTL++GVNLPARRVI R P +D Y QM GRAGR G+DT G
Sbjct: 430 AFRQGFIRVLAATSTLSSGVNLPARRVIIRTPIFSGQPLDILTYKQMVGRAGRKGVDTMG 489
Query: 353 ESVLICKPQELKKVMGLLNESCPPLHSCL---SEDLNGMTHAILEVVAGGIVQTANDIH- 408
ES+L+CK E K + LL S P+HSCL E M AILE++ GG+ T+ D+
Sbjct: 490 ESILVCKNSEKSKGIALLQGSLEPVHSCLQRQGEVTASMIRAILEIIVGGVASTSQDMQT 549
Query: 409 --------------RKFLEWNEDT------------------------------KLYSTT 424
++ ++ N+D K+Y T
Sbjct: 550 YAACTFLAAAIQEGKQGMQRNQDDAQLGAIDACVTWLLENEFIQVAEPGDGTGGKVYHPT 609
Query: 425 PLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVD-VEPDWESYYER 483
LG A+ SSL P ++L + ADL RA +GFVL +DLH+VYLVTP+ D + DW ++
Sbjct: 610 HLGSATLSSSLSPTDTLDIFADLQRAMKGFVLENDLHIVYLVTPVFEDWISIDWYRFFCL 669
Query: 484 FVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNSDDQT 543
+ KL + V VGV E FL R G + + + QH +
Sbjct: 670 WEKLPTSMKRVAELVGVEEGFLARCVKGKVVA---------RTERQH-----------RQ 709
Query: 544 LRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCERLGWH 603
+ + KRF+ +L+L L+ E P+ ++ + + RG +Q LQ++A +A M+ VF RLGWH
Sbjct: 710 MAIHKRFFTSLVLLDLISEIPLKDINQKYGCNRGQIQSLQQSAAVYAGMITVFSNRLGWH 769
Query: 604 DFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEASIPELVKA 663
+ E L+++FQ R++FG++ E+ +L + + RAR LY +G T +A A E+ A
Sbjct: 770 NMELLLSQFQKRLTFGIQRELCDLIRVSLLNAQRARFLYASGFLTVADLARADSAEVEVA 829
Query: 664 LFES 667
L S
Sbjct: 830 LKNS 833
Score = 101 bits (251), Expect = 2e-19
Identities = 55/129 (42%), Positives = 77/129 (59%), Gaps = 2/129 (1%)
Query: 1214 VNARDYFVPTQDNWLLLTADYSQIELRLMAHFSKDSTLIELLRKPDGDVFTMIAARWIGC 1273
V+ R FVP L+L ADYSQ+ELR++AH S+D LI++L DVF IAA W
Sbjct: 2266 VSMRHAFVPFPGG-LILAADYSQLELRILAHLSRDCRLIQVLNT-GADVFRSIAAEWKMI 2323
Query: 1274 PEVSVGSRQREQTKKMVYGILYGMGPNSLAEQMDCTSDEASERISNFKSTFPGVASWLHE 1333
+VG R+ K++ YGI+YGMG SL EQM ++A+ I +FKS + G+ ++ +
Sbjct: 2324 EPDAVGDDLRQHAKQICYGIIYGMGAKSLGEQMGIKENDAASYIDSFKSRYKGINHFMRD 2383
Query: 1334 AVAFCRSKG 1342
V CR G
Sbjct: 2384 TVKNCRKNG 2392
Score = 61.6 bits (148), Expect = 2e-07
Identities = 37/96 (38%), Positives = 55/96 (56%), Gaps = 1/96 (1%)
Query: 1109 LLVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCIQARKLLVKRLKQLEKEAYKLAG 1168
LL E L + ++E+P LA +EL GIG C + ++ +L +E +AY+LAG
Sbjct: 2018 LLQKENLHDIFCKVEMPSQYCLALLELNGIGFSTAECESQKHVMQAKLDAIETQAYQLAG 2077
Query: 1169 MTFSLSMPADIAKVLFEHLKLPIPDGKNKGKNHPST 1204
+FS + DIA+VLF LKLP P+G+ K + T
Sbjct: 2078 HSFSFTSADDIAQVLFLELKLP-PNGEMKTQGSKKT 2112
>UniRef100_Q7TQC0 DNA polymerase Q [Mus musculus]
Length = 2587
Score = 486 bits (1250), Expect = e-135
Identities = 287/724 (39%), Positives = 407/724 (55%), Gaps = 87/724 (12%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+ +LP+VS+ EK +L+ L + +G V Y G+ +AVCTIE+AN L+N
Sbjct: 182 ALFILPFVSVAKEKKCYLQSLFQEVGLKVDGYMGSTSPTGQFSSLDIAVCTIERANGLVN 241
Query: 62 RLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSD 121
RL+EE ++ +G++V+DELHM+GD RGYLLEL+LTK+ Y KS+ + S+
Sbjct: 242 RLIEENKMDLLGMVVVDELHMLGDSHRGYLLELLLTKICYVT----RKSASHQAESASTL 297
Query: 122 KNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSR 181
N +QIVGMSAT+PN+ VA WL A LY T+FRPVPL E IK+GNSIY+ SM+L R
Sbjct: 298 SN----AVQIVGMSATLPNLQLVASWLNAELYHTDFRPVPLLESIKIGNSIYDSSMKLVR 353
Query: 182 TIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKFLKSF------ 235
+ G D DH+V LC E +Q+ SVLIFC S+K CE A +A+ +
Sbjct: 354 EFQPLLQVKG-DEDHIVSLCYETIQDNHSVLIFCPSKKWCEKVADIIAREFYNLHHQPEG 412
Query: 236 TVDINENNCEFAD---ITSAINSLRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREIVET 292
V +E D + ++ L++ P+GLD VL+ T P GVAFHHAGLT EER+I+E
Sbjct: 413 LVKSSEFPPVILDQKSLLEVMDQLKRSPSGLDSVLKNTVPWGVAFHHAGLTFEERDIIEG 472
Query: 293 CYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGIDTKG 352
+R+G +RVL ATSTL++GVNLPARRVI R P +D Y QM GRAGR G+DT G
Sbjct: 473 AFRQGFIRVLAATSTLSSGVNLPARRVIIRTPIFSGQPLDILTYKQMVGRAGRKGVDTMG 532
Query: 353 ESVLICKPQELKKVMGLLNESCPPLHSCL---SEDLNGMTHAILEVVAGGIVQTANDIH- 408
ES+L+CK E K + LL S P+HSCL E M AILE++ GG+ T+ D+
Sbjct: 533 ESILVCKNSEKSKGIALLQGSLEPVHSCLQRQGEVTASMIRAILEIIVGGVASTSQDMQT 592
Query: 409 --------------RKFLEWNEDT------------------------------KLYSTT 424
++ ++ N+D K+Y T
Sbjct: 593 YAACTFLAAAIQEGKQGMQRNQDDAQLGAIDACVTWLLENEFIQVAEPGDGTGGKVYHPT 652
Query: 425 PLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVD-VEPDWESYYER 483
LG A+ SSL P ++L + ADL RA +GFVL +DLH+VYLVTP+ D + DW ++
Sbjct: 653 HLGSATLSSSLSPTDTLDIFADLQRAMKGFVLENDLHIVYLVTPVFEDWISIDWYRFFCL 712
Query: 484 FVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNSDDQT 543
+ KL + V VGV E FL R G + + + QH +
Sbjct: 713 WEKLPTSMKRVAELVGVEEGFLARCVKGKVVA---------RTERQH-----------RQ 752
Query: 544 LRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCERLGWH 603
+ + KRF+ +L+L L+ E P+ ++ + + RG +Q LQ++A +A M+ VF RLGWH
Sbjct: 753 MAIHKRFFTSLVLLDLISEIPLKDINQKYGCNRGQIQSLQQSAAVYAGMITVFSNRLGWH 812
Query: 604 DFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEASIPELVKA 663
+ E L+++FQ R++FG++ E+ +L + + RAR LY +G T +A A E+ A
Sbjct: 813 NMELLLSQFQKRLTFGIQRELCDLIRVSLLNAQRARFLYASGFLTVADLARADSAEVEVA 872
Query: 664 LFES 667
L S
Sbjct: 873 LKNS 876
Score = 101 bits (251), Expect = 2e-19
Identities = 55/129 (42%), Positives = 77/129 (59%), Gaps = 2/129 (1%)
Query: 1214 VNARDYFVPTQDNWLLLTADYSQIELRLMAHFSKDSTLIELLRKPDGDVFTMIAARWIGC 1273
V+ R FVP L+L ADYSQ+ELR++AH S+D LI++L DVF IAA W
Sbjct: 2309 VSMRHAFVPFPGG-LILAADYSQLELRILAHLSRDCRLIQVLNT-GADVFRSIAAEWKMI 2366
Query: 1274 PEVSVGSRQREQTKKMVYGILYGMGPNSLAEQMDCTSDEASERISNFKSTFPGVASWLHE 1333
+VG R+ K++ YGI+YGMG SL EQM ++A+ I +FKS + G+ ++ +
Sbjct: 2367 EPDAVGDDLRQHAKQICYGIIYGMGAKSLGEQMGIKENDAASYIDSFKSRYKGINHFMRD 2426
Query: 1334 AVAFCRSKG 1342
V CR G
Sbjct: 2427 TVKNCRKNG 2435
Score = 61.6 bits (148), Expect = 2e-07
Identities = 37/96 (38%), Positives = 55/96 (56%), Gaps = 1/96 (1%)
Query: 1109 LLVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCIQARKLLVKRLKQLEKEAYKLAG 1168
LL E L + ++E+P LA +EL GIG C + ++ +L +E +AY+LAG
Sbjct: 2061 LLQKENLHDIFCKVEMPSQYCLALLELNGIGFSTAECESQKHVMQAKLDAIETQAYQLAG 2120
Query: 1169 MTFSLSMPADIAKVLFEHLKLPIPDGKNKGKNHPST 1204
+FS + DIA+VLF LKLP P+G+ K + T
Sbjct: 2121 HSFSFTSADDIAQVLFLELKLP-PNGEMKTQGSKKT 2155
>UniRef100_Q96SE4 DNA polymerase theta [Homo sapiens]
Length = 2724
Score = 484 bits (1245), Expect = e-134
Identities = 287/721 (39%), Positives = 409/721 (55%), Gaps = 92/721 (12%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+ +LP+VS+ EK +L+ L + +G V Y G+ +AVCTIE+AN LIN
Sbjct: 273 ALFILPFVSVAKEKKYYLQSLFQEVGIKVDGYMGSTSPSRHFSSLDIAVCTIERANGLIN 332
Query: 62 RLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSD 121
RL+EE ++ +G++V+DELHM+GD RGYLLEL+LTK+ Y + S +D S ++
Sbjct: 333 RLIEENKMDLLGMVVVDELHMLGDSHRGYLLELLLTKICYITRKSASCQADLASSLSNA- 391
Query: 122 KNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSR 181
+QIVGMSAT+PN+ VA WL A LY T+FRPVPL E +KVGNSIY+ SM+L R
Sbjct: 392 -------VQIVGMSATLPNLELVASWLNAELYHTDFRPVPLLESVKVGNSIYDSSMKLVR 444
Query: 182 TIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKFLKSFTVD--- 238
+ G D DHVV LC E + + SVL+FC S+K CE A +A+ +
Sbjct: 445 EFEPMLQVKG-DEDHVVSLCYETICDNHSVLLFCPSKKWCEKLADIIAREFYNLHHQAEG 503
Query: 239 ---INENNC-----EFADITSAINSLRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREIV 290
+ + C E ++ ++ LR+ P+GLD VL++T P GVAFHHAGLT EER+I+
Sbjct: 504 EGLVKPSECPPVILEQKELLEVMDQLRRLPSGLDSVLQKTVPWGVAFHHAGLTFEERDII 563
Query: 291 ETCYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGIDT 350
E +R+GL+RVL ATSTL++GVNLPARRVI R P G +D Y QM GRAGR G+DT
Sbjct: 564 EGAFRQGLIRVLAATSTLSSGVNLPARRVIIRTPIFGGRPLDILTYKQMVGRAGRKGVDT 623
Query: 351 KGESVLICKPQELKKVMGLLNESCPPLHSCL----SEDLNG-MTHAILEVVAGGIVQTAN 405
G S+LICK E K + LL S P+ SCL E++ G M AILE++ GG+ T+
Sbjct: 624 VG-SILICKNSEKSKGIALLQGSLKPVRSCLQRREGEEVTGSMIRAILEIIVGGVASTSQ 682
Query: 406 DIH----------------------------------------RKFLEWNE-----DTKL 420
D+H +F++ E + K+
Sbjct: 683 DMHTYAACTFLAASMKEGKQGIQRNQESVQLGAIEACVMWLLENEFIQSTEASDGTEGKV 742
Query: 421 YSTTPLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVD-VEPDWES 479
Y T LG A+ SSL P ++L + ADL RA +GFVL +DLH++YLVTP+ D DW
Sbjct: 743 YHPTHLGSATLSSSLSPADTLDIFADLQRAMKGFVLENDLHILYLVTPMFEDWTTIDWYR 802
Query: 480 YYERFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNS 539
++ + KL + V VGV E FL R G + + + QH
Sbjct: 803 FFCLWEKLPTSMKRVAELVGVEEGFLARCVKGKVVA---------RTERQH--------- 844
Query: 540 DDQTLRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCER 599
+ + + KRF+ +L+L L+ E P+ E+ + + RG +Q LQ++A +A M+ VF R
Sbjct: 845 --RQMAIHKRFFTSLVLLDLISEVPLREINQKYGCNRGQIQSLQQSAAVYAGMITVFSNR 902
Query: 600 LGWHDFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEASIPE 659
LGWH+ E L+++FQ R++FG++ E+ +L + + RAR LY +G T +A A+I E
Sbjct: 903 LGWHNMELLLSQFQKRLTFGIQRELCDLVRVSLLNAQRARVLYASGFHTVADLARANIVE 962
Query: 660 L 660
+
Sbjct: 963 V 963
Score = 99.0 bits (245), Expect = 1e-18
Identities = 60/162 (37%), Positives = 84/162 (51%), Gaps = 11/162 (6%)
Query: 1191 IPDGKNKGKNHPSTGKHCLDALRVNARDYFVPTQDNWL----------LLTADYSQIELR 1240
+P G+ K K S C + A D +P + +L ADYSQ+ELR
Sbjct: 2412 LPMGRGKYKKGFSVNPRCQAQMEERAADRGMPFSISMRHAFVPFPGGSILAADYSQLELR 2471
Query: 1241 LMAHFSKDSTLIELLRKPDGDVFTMIAARWIGCPEVSVGSRQREQTKKMVYGILYGMGPN 1300
++AH S D LI++L DVF IAA W SVG R+Q K++ YGI+YGMG
Sbjct: 2472 ILAHLSHDRRLIQVLNT-GADVFRSIAAEWKMIEPESVGDDLRQQAKQICYGIIYGMGAK 2530
Query: 1301 SLAEQMDCTSDEASERISNFKSTFPGVASWLHEAVAFCRSKG 1342
SL EQM ++A+ I +FKS + G+ ++ E V C+ G
Sbjct: 2531 SLGEQMGIKENDAACYIDSFKSRYTGINQFMTETVKNCKRDG 2572
Score = 61.6 bits (148), Expect = 2e-07
Identities = 52/174 (29%), Positives = 81/174 (45%), Gaps = 11/174 (6%)
Query: 1038 DMCIVAWILWPDEESSSSPNLDKEVKKRLSPE----DAAAANQCGRWRNQMRKAAHNGCC 1093
D + W+L PD S P L V L E + +Q + + H+G
Sbjct: 2122 DPKVACWLLDPD---SQEPTLHSIVTSFLPHELPLLEGMETSQGIQSLGLNAGSEHSGRY 2178
Query: 1094 RRVAQTRAL---CSVLWKLLVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCIQARK 1150
R ++ + + L LL E L + ++E+P LA +EL GIG C +
Sbjct: 2179 RASVESILIFNSMNQLNSLLQKENLQDVFRKVEMPSQYCLALLELNGIGFSTAECESQKH 2238
Query: 1151 LLVKRLKQLEKEAYKLAGMTFSLSMPADIAKVLFEHLKLPIPDGKNKGKNHPST 1204
++ +L +E +AY+LAG +FS + DIA+VLF LKLP P+ + K + T
Sbjct: 2239 IMQAKLDAIETQAYQLAGHSFSFTSSDDIAEVLFLELKLP-PNREMKNQGSKKT 2291
Score = 41.2 bits (95), Expect = 0.26
Identities = 43/159 (27%), Positives = 64/159 (40%), Gaps = 60/159 (37%)
Query: 1448 QGSAADIIKIAMIKIYSEI--FPGVDK--------LDSSSSVTAKFEMLRDR-CRI---- 1492
QGSAADI+KIA + I ++ F K L S + ++ L+ C I
Sbjct: 2608 QGSAADIVKIATVNIQKQLETFHSTFKSHGHREGMLQSDRTGLSRKRKLQGMFCPIRGGF 2667
Query: 1493 -LLQVHDELVLEVDPSVVKEAALLLQTSMENAVSLLGLYSLNKLFFWPFLFGCRHKLVKV 1551
+LQ+HDEL+ EV V + A +++ ME+AV L
Sbjct: 2668 FILQLHDELLYEVVEEDVVQVAQIVKNEMESAVKL------------------------- 2702
Query: 1552 IEDLTVWSNHIFTVYAYASAVPLNVKLKVGRTWGSLEPF 1590
+V L VK+K+G +WG L+ F
Sbjct: 2703 -------------------SVKLKVKVKIGASWGELKDF 2722
>UniRef100_Q6ZM94 Novel protein similar to humna DNA-directed polymerase theta
[Brachydanio rerio]
Length = 2254
Score = 476 bits (1224), Expect = e-132
Identities = 322/935 (34%), Positives = 467/935 (49%), Gaps = 153/935 (16%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+ +LP+VS+ EK +L+ + + G V Y G+ VAVCTIEKAN L+N
Sbjct: 86 AMFILPFVSVAREKMFYLQNVFQEAGIRVEGYMGSTSAAGGFSALDVAVCTIEKANGLVN 145
Query: 62 RLLEEGRLSEMG---------------IIVIDELHMVGDPKRGYLLELMLTKLRYAAGEG 106
RL+EE +L +G +V+DELHMVGD RGYLLEL+LTK+RY A +
Sbjct: 146 RLIEEDKLDLLGKNNKKYLASYNVVTGTVVVDELHMVGDSGRGYLLELLLTKIRYIAQKT 205
Query: 107 ISKSSDGEGSGGSSDKNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYI 166
+++S S G+QI+GMSAT+PN+ +A WL A LY T +RPVPL E++
Sbjct: 206 ATRNSGQSTS----------TGVQIIGMSATLPNLDLLARWLSAELYSTNYRPVPLMEWV 255
Query: 167 KVGNSIYNKSMELSRTIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTAR 226
K+G +IY+ S+ L D DH+V LC E VQ+G S L+FC S+ CE A
Sbjct: 256 KIGTNIYDGSLNLG------------DDDHIVSLCFETVQDGHSALLFCPSKNWCEKLAD 303
Query: 227 HVAKFLKSF------------TVDINENNCEFADITSAINSLRKCPAGLDPVLEETFPAG 274
+ + + ++ +N+ + + L++ PAGLD VL+ T P G
Sbjct: 304 SIGREFYNLHHKEMQSGSGGQSIFLNQEG-----LLDVLAQLKRTPAGLDHVLQRTVPWG 358
Query: 275 VAFHHAGLTVEEREIVETCYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGT 334
VAFHHAGLT +ER+I+E +R+G +RVL ATSTL++GVNLPARRVI R P +D
Sbjct: 359 VAFHHAGLTFDERDILEGAFRQGYIRVLAATSTLSSGVNLPARRVIIRTPVFNGHLLDIL 418
Query: 335 RYMQMAGRAGRTGIDTKGESVLICKPQELKKVMGLLNESCPPLHSCLSED-----LNGMT 389
Y QM GRAGR G+DT GESVL+CK E K M L+ S P+ SCL + M
Sbjct: 419 TYKQMVGRAGRKGVDTIGESVLVCKEAERAKGMSLIQGSLKPISSCLVKREGEGVTTSML 478
Query: 390 HAILEVVAGGIVQTANDIH--------------------------------RKFLEW--- 414
AILE++ GG+ + D+ +EW
Sbjct: 479 RAILEIIVGGVASSPQDVRMYAACTLLAASIAAEEAHQDGSESEARNKGAIEACIEWLMD 538
Query: 415 NE--------DTKLYSTTPLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLV 466
NE D + Y T LG A+ SSL P E+L + ADL RA +GFVL +DLH++Y +
Sbjct: 539 NEFIHIQKEGDVERYCPTHLGSATLSSSLSPPEALGIFADLQRAMKGFVLENDLHILYQI 598
Query: 467 TPINVD-VEPDWESYYERFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNK 525
TP+ VD DW ++ + +L + V VG+ E FL R G + + + +
Sbjct: 599 TPVYVDWTTIDWYQFFCLWEQLPSAMKRVAEMVGIQEGFLARSVGGKLIAKTEKQ----R 654
Query: 526 RQNQHGMSSGIVNSDDQTLRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQEN 585
RQ + + KRF+ L+L LV E P+G V + + +RG +Q LQ++
Sbjct: 655 RQ----------------MAIHKRFFTTLVLLDLVSEEPLGAVAKKYGCSRGQLQSLQQS 698
Query: 586 AGRFASMVAVFCERLGWHDFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAG 645
A +A MV VFC RLGWH+ E L+++FQ+R+SFGV+ E+ +L I + RAR LY +G
Sbjct: 699 ASTYAGMVTVFCNRLGWHNLELLLSQFQSRLSFGVQRELCDLVRISLLTAQRARTLYSSG 758
Query: 646 LRTPLAIAEASIPELVKAL-----FESSSWGTEGSAQRSLQFGVAKKIKNGARKIVLDK- 699
T +A A + E+ KAL F+SS + S + + + I +K + ++
Sbjct: 759 FVTVAELARADVSEVEKALRKAIPFKSSRQAVDESEVEAQERKSMRCIWVSGKKALTERE 818
Query: 700 -----AEEARIAAFSAFKSLGYDVPQFAPPISTAVCNSIRKEVGSSSGSDTADTSHS--- 751
EA++ LG + P T NS + + S + T H
Sbjct: 819 AAQQIVAEAQLLLQKDLALLGVEWSPACLPAKTQPDNSSTVKSNTEPRSMSGGTEHEGDQ 878
Query: 752 -----------FIDTNHIDNSNVP--ALEKEKDLIKSSD-NGALVSVEGKSDSVMPHSLS 797
++ N +NS+ P LE + K+ D + + S E + D S
Sbjct: 879 DLMSNVTEEKLLLENNSDNNSHPPLRPLESTTNSEKTMDVDSGVSSAECQPDKKCELQSS 938
Query: 798 TVPVVVPSINELSMTSGPAKIPDVTTLSVHLQKQN 832
+ V+ SIN + G V + S LQ++N
Sbjct: 939 VLHKVLKSIN--TKDKGCDNNHTVESSSETLQRRN 971
Score = 100 bits (248), Expect = 5e-19
Identities = 55/129 (42%), Positives = 74/129 (56%), Gaps = 2/129 (1%)
Query: 1214 VNARDYFVPTQDNWLLLTADYSQIELRLMAHFSKDSTLIELLRKPDGDVFTMIAARWIGC 1273
V+ R FVP L+L DYSQ+ELR++AH S+D L+ +L DVF IAA W
Sbjct: 1984 VSMRHAFVPFSGG-LILAVDYSQLELRILAHLSRDRRLLHVLNS-GADVFKSIAAEWKMV 2041
Query: 1274 PEVSVGSRQREQTKKMVYGILYGMGPNSLAEQMDCTSDEASERISNFKSTFPGVASWLHE 1333
SV R+Q K++ YGI+YGMG SL EQM ++A+ I FKS + G+ ++L E
Sbjct: 2042 DPASVDDNMRQQAKQICYGIIYGMGAKSLGEQMGIEENDAACYIETFKSRYNGIQNFLRE 2101
Query: 1334 AVAFCRSKG 1342
V C G
Sbjct: 2102 TVQKCGKNG 2110
Score = 69.7 bits (169), Expect = 7e-10
Identities = 43/118 (36%), Positives = 65/118 (54%), Gaps = 2/118 (1%)
Query: 1109 LLVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCIQARKLLVKRLKQLEKEAYKLAG 1168
LL + ++ ++E+P LA +EL GIG + C + ++ +L LE +AY+LAG
Sbjct: 1743 LLEKDGFLDVFKKVEMPTQYCLALLELNGIGFSIAECEAQKHVMQAKLSALESQAYQLAG 1802
Query: 1169 MTFSLSMPADIAKVLFEHLKLPIPDGKNKG-KNHPSTGKHCLDALRVNARDYFVPTQD 1225
+FSL+ P D+A+VLF LKLP P+G G KN + G R+ F T+D
Sbjct: 1803 HSFSLTSPEDVAEVLFLELKLP-PNGDLNGLKNKKTLGYTRRAGARIKLSKQFSTTKD 1859
Score = 49.3 bits (116), Expect = 0.001
Identities = 36/102 (35%), Positives = 51/102 (49%), Gaps = 10/102 (9%)
Query: 1434 VSIHVNIVFLPSTSQGSAADIIKIAMIKIY---SEIFPGVDKLDSSSSVTA------KFE 1484
+ H + +T QGSAADI+K+A I I E FPGV S+ +F
Sbjct: 2132 IKSHAERQAVNTTVQGSAADIVKLATINIQRRIEEAFPGVPTSHQHPSIRLGGRHRNQFR 2191
Query: 1485 MLRDRCRILLQVHDELVLEVDPSVVKEAALLLQTSMENAVSL 1526
LR +LQ+HDEL+ EV V + A +++ ME+ V L
Sbjct: 2192 PLRGGY-FILQLHDELIYEVAEEDVIQVAQIVKREMESVVKL 2232
>UniRef100_UPI00003A9B24 UPI00003A9B24 UniRef100 entry
Length = 764
Score = 462 bits (1189), Expect = e-128
Identities = 281/733 (38%), Positives = 399/733 (54%), Gaps = 104/733 (14%)
Query: 2 AILVLPYVSICTEK----------------AEH-----LEKLLEPLGKHVRSYYGNQGGG 40
A+ +LP+VS+ EK A+H ++ L + + V Y G+
Sbjct: 65 ALFILPFVSVAKEKKCYLQVSSMQGRFITLAQHSISFGIQALFQEVDMRVGGYMGSISPA 124
Query: 41 SLPKDTSVAVCTIEKANSLINRLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLR 100
VAVCTIEKAN LINRL+EE ++ +G++V+DELHM+GD RGYLLEL+LTK+R
Sbjct: 125 GRFSLLDVAVCTIEKANGLINRLIEENQMDSLGVVVVDELHMLGDSHRGYLLELLLTKVR 184
Query: 101 YAAGEGISKSSDGEGSGGSSDKNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPV 160
Y K++ G GG +Q+VGMSAT+PN+ +A WL A LY T+FRPV
Sbjct: 185 YIT----EKAAKSPGFGG----------IQVVGMSATLPNLGLLASWLDAELYCTDFRPV 230
Query: 161 PLEEYIKVGNSIYNKSMELSRTIPKGADLGGK---------------------DPDHVVE 199
PL+E++K+GN+IY+ SM L R + G K D DHVV
Sbjct: 231 PLKEWVKIGNNIYDSSMNLVREAQTSTE-GNKTLSSGFWLRTFSIAKVKKTATDEDHVVS 289
Query: 200 LCNEVVQEGQSVLIFCSSRKGCESTARHVAKFLKSFTVDINENNCEFADITSAINSLRKC 259
LC E V +G SVL+FC S+ CE A +A+ + +++ E + I ++ LR+
Sbjct: 290 LCYETVCDGHSVLLFCPSKNWCEKLADIIAR--EFYSLQQAEIVVDREGIDEVLDQLRRS 347
Query: 260 PAGLDPVLEETFPAGVAFHHAGLTVEEREIVETCYRKGLLRVLTATSTLAAGVNLPARRV 319
+GLD VL+ T P GVAFHHAGLT +ER+I+E +R+ +RVL ATSTL++GVNLPARRV
Sbjct: 348 LSGLDSVLQRTLPWGVAFHHAGLTFDERDIIEGAFRQSTIRVLAATSTLSSGVNLPARRV 407
Query: 320 IFRQPRIGCDFIDGTRYMQMAGRAGRTGIDTKGESVLICKPQELKKVMGLLNESCPPLHS 379
I R P G +D Y QMAGRAGR G+DT+GES+L+CKP E K LL S P+ S
Sbjct: 408 IIRTPMFGGTLLDVLTYKQMAGRAGRKGVDTEGESILVCKPSERSKGTALLQGSLKPVRS 467
Query: 380 CLSED-----LNGMTHAILEV-------------------VAGGIVQTANDIHRKFLEWN 415
CL + M AILEV V + I+ +
Sbjct: 468 CLLRKEGEGVASSMKRAILEVRDMWRGSRTLACTARMVYFVIPSNIVYITCIYVLIICLF 527
Query: 416 EDTKLYSTTPLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVD-VE 474
K++ T LG A+ SSL P E++ + +DL RA + FVL +DLH+VYLVTP+ D
Sbjct: 528 LTAKIFHPTHLGSATLSSSLSPTEAMEIFSDLQRAMKSFVLENDLHIVYLVTPVYEDWTT 587
Query: 475 PDWESYYERFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSS 534
DW ++ + KL + V VG+ E FL R G + ++
Sbjct: 588 IDWYQFFCLWEKLPASMKRVAELVGIEEGFLARSVKGKITAKTEKQY------------- 634
Query: 535 GIVNSDDQTLRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVA 594
+ + + KRF+ +L L L+ E P+ ++ + + +RG +Q LQ++A +A MV
Sbjct: 635 -------RQMAIHKRFFTSLALLDLISEVPLKDMTKKYGCSRGQLQSLQQSAATYAGMVT 687
Query: 595 VFCERLGWHDFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAE 654
VFC RLGWH+ E L+++FQ+R++FGV E+ +L + + RAR LY AG T +A+
Sbjct: 688 VFCNRLGWHNMELLLSQFQSRLTFGVHRELCDLVRVSLLNAQRARMLYNAGFVTVADLAK 747
Query: 655 ASIPELVKALFES 667
AS ++ AL S
Sbjct: 748 ASPGDVATALKNS 760
>UniRef100_Q5TX00 ENSANGP00000027910 [Anopheles gambiae str. PEST]
Length = 602
Score = 446 bits (1148), Expect = e-123
Identities = 265/647 (40%), Positives = 372/647 (56%), Gaps = 63/647 (9%)
Query: 18 HLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLINRLLEEGRLSEMGIIVI 77
+L+ LLEP G V +YG + +AVCTIEKANS++NRLLE+ L+ +G++V+
Sbjct: 1 YLKDLLEPGGMRVEGFYGGYHPPGGFESVDLAVCTIEKANSIVNRLLEQSALTTLGLVVV 60
Query: 78 DELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSDKNDPAQGLQIVGMSAT 137
DE H++ DP RGY+LEL+LTK+R+ A + +QIV MSAT
Sbjct: 61 DEAHLISDPGRGYILELLLTKIRFVAARCEHR-------------------IQIVCMSAT 101
Query: 138 MPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSRTIPKGADLG---GKDP 194
+PN+ +A WL+A LY T+FRP+ L E +KVGN+IY+ S E R + KG G KD
Sbjct: 102 LPNIDLLARWLEADLYHTDFRPIALVEMLKVGNTIYSASGEAIRYL-KGTLHGYTVPKDA 160
Query: 195 DHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKFLKSFTVDINENNCEFADITSAIN 254
DHV LC E + +G +V++FC S+ CE A +A L + + + ++ + ++
Sbjct: 161 DHVALLCLETILDGCAVIVFCPSKDWCEQLAISLASTLHTLRKENHPHDELRRRLREQLD 220
Query: 255 S---------LRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREIVETCYRKGLLRVLTAT 305
LR CPAGLD VLE+T GVAFHHAGLT +ER+I+E +R G LR++ AT
Sbjct: 221 GERQEEVLLQLRNCPAGLDSVLEKTVRYGVAFHHAGLTTDERDIIEGSFRDGALRIIVAT 280
Query: 306 STLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGIDTKGESVLICKPQELKK 365
STL++GVNLPARRVI R P+ G + Y QM GRAGRTG DT GES+LIC P E K
Sbjct: 281 STLSSGVNLPARRVIVRTPKFGGKPMSSLTYKQMIGRAGRTGRDTLGESILICTPAEEKI 340
Query: 366 VMGLLNESCPPLHSCL-SEDLNGMTHAILEVVAGGIVQTANDIHRKFLEWN--EDTKLYS 422
L+ PP+ SCL SE+ + AILE++A G T ++ F+ D + S
Sbjct: 341 GRELIGAELPPVRSCLDSENYAHLKRAILEIIASGSATTTQEL-ETFVNATLYIDQTVLS 399
Query: 423 TTPLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVDV---EPDWES 479
T LG+A +SL P++ ++ ++L RAR+ FVL S+LH +YLVTP +V + DW
Sbjct: 400 ATRLGQACLSASLPPKDGFLLFSELQRARQCFVLESELHAIYLVTPYSVAYQWQQIDWMD 459
Query: 480 YYERFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNS 539
+ + + KL + VG VGV E F++R G N
Sbjct: 460 FLDLWEKLPSASKRVGELVGVKESFMVRAMRGA------------------------ANL 495
Query: 540 DDQTLRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCER 599
D +TL++ KRFY AL L LV E P+ V FK RG++Q LQ+ + FA +V FC
Sbjct: 496 DYRTLQIHKRFYTALALLDLVNEVPLCTVARRFKCCRGLLQSLQQVSSTFAGIVTSFCAS 555
Query: 600 LGWHDFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGL 646
L W + LVA+F+ R+ FGV E+++L IP + G RAR L+ +G+
Sbjct: 556 LNWTLLQLLVAQFRERLFFGVAHELLDLMRIPSLNGQRARLLHDSGI 602
>UniRef100_Q7PT13 ENSANGP00000019077 [Anopheles gambiae str. PEST]
Length = 840
Score = 446 bits (1147), Expect = e-123
Identities = 277/754 (36%), Positives = 402/754 (52%), Gaps = 112/754 (14%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+L+LP+V++ EK +L+ LLEP G V +YG + +AVCTIEKANS++N
Sbjct: 87 AMLILPFVAVAREKMLYLKDLLEPGGMRVEGFYGGYHPPGGFESVDLAVCTIEKANSIVN 146
Query: 62 RLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSD 121
RLLE+ L+ +G++V+DE H++ DP RGY+LEL+LTK+R+ A +
Sbjct: 147 RLLEQSALTTLGLVVVDEAHLISDPGRGYILELLLTKIRFVAARCEHR------------ 194
Query: 122 KNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSR 181
+QIV MSAT+PN+ +A WL+A LY T+FRP+ L E +KVGN+IY+ S E R
Sbjct: 195 -------IQIVCMSATLPNIDLLARWLEADLYHTDFRPIALVEMLKVGNTIYSASGEAIR 247
Query: 182 TIPKGADLG---GKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKFLKSFTVD 238
+ KG G KD DHV LC E + +G +V++FC S+ CE A +A L + +
Sbjct: 248 YL-KGTLHGYTVPKDADHVALLCLETILDGCAVIVFCPSKDWCEQLAISLASTLHTLRKE 306
Query: 239 INENNCEFADITSAINS---------LRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREI 289
+ ++ + ++ LR CPAGLD VLE+T GVAFHHAGLT +ER+I
Sbjct: 307 NHPHDELRRRLREQLDGERQEEVLLQLRNCPAGLDSVLEKTVRYGVAFHHAGLTTDERDI 366
Query: 290 VETCYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGID 349
+E +R G LR++ ATSTL++GVNLPARRVI R P+ G + Y QM GRAGRTG D
Sbjct: 367 IEGSFRDGALRIIVATSTLSSGVNLPARRVIVRTPKFGGKPMSSLTYKQMIGRAGRTGRD 426
Query: 350 TKGESVLICKPQELKKVMGLLNESCPPLHSCL-SEDLNGMTHAILEVVAGGIVQTANDIH 408
T GES+LIC P E K L+ PP+ SCL SE+ + AILE++A G T ++
Sbjct: 427 TLGESILICTPAEEKIGRELIGAELPPVRSCLDSENYAHLKRAILEIIASGSATTTQELE 486
Query: 409 R-------------KFLEWNEDT------------------------------------- 418
+ + NE+T
Sbjct: 487 TFVNATLSKKLPTGEEEDENEETDPIVSCISFLLEYEFIRCLQQDIVEEDGSTTATPKST 546
Query: 419 --KLYSTTPLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVDV--- 473
+ S T LG+A +SL P++ ++ ++L RAR+ FVL S+LH +YLVTP +V
Sbjct: 547 KRTVLSATRLGQACLSASLPPKDGFLLFSELQRARQCFVLESELHAIYLVTPYSVAYQWQ 606
Query: 474 EPDWESYYERFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMS 533
+ DW + + + KL + VG VGV E F++R G
Sbjct: 607 QIDWMDFLDLWEKLPSASKRVGELVGVKESFMVRAMRGA--------------------- 645
Query: 534 SGIVNSDDQTLRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMV 593
N D +TL++ KRFY AL L LV E P+ V FK RG++Q LQ+ + FA +V
Sbjct: 646 ---ANLDYRTLQIHKRFYTALALLDLVNEVPLCTVARRFKCCRGLLQSLQQVSSTFAGIV 702
Query: 594 AVFCERLGWHDFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIA 653
FC L W + LVA+F+ R+ FGV E+++L IP + G RAR L+ +G+ + +A
Sbjct: 703 TSFCASLNWTLLQLLVAQFRERLFFGVAHELLDLMRIPSLNGQRARLLHDSGITGLVQLA 762
Query: 654 EASIPELVKALFESSSWGTEGSAQRSLQFGVAKK 687
+ + L +S+ E + ++ ++
Sbjct: 763 NSDRLAVETILHHRTSFEAERVRENENEYDAERR 796
>UniRef100_O18475 CG6019-PA [Drosophila melanogaster]
Length = 2059
Score = 422 bits (1085), Expect = e-116
Identities = 267/726 (36%), Positives = 379/726 (51%), Gaps = 103/726 (14%)
Query: 3 ILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLINR 62
+L+LP++S+ EK +++ LL P G V +YG + VA+CTIEKANS++N+
Sbjct: 282 LLILPFISVVREKMFYMQDLLTPAGYRVEGFYGGYTPPGGFESLHVAICTIEKANSIVNK 341
Query: 63 LLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGSSDK 122
L+E+G+L +G++V+DE+H++ D RGY+LEL+L K+ Y +
Sbjct: 342 LMEQGKLETIGMVVVDEVHLISDKGRGYILELLLAKILYMSRRN---------------- 385
Query: 123 NDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSMELSRT 182
+Q++ MSAT+ NV + WL A LY T +RPV L+E IKVG IY+ ++L R
Sbjct: 386 ---GLQIQVITMSATLENVQLLQSWLDAELYITNYRPVALKEMIKVGTVIYDHRLKLVRD 442
Query: 183 IPKGADLGG---KDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKFL----KSF 235
+ K L D D V LC E + EG SV++FC S+ CE+ A +A + KS
Sbjct: 443 VAKQKVLLKGLENDSDDVALLCIETLLEGCSVIVFCPSKDWCENLAVQLATAIHVQIKSE 502
Query: 236 TV--DINENNCEFADITSAINSLRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREIVETC 293
TV N I LR P GLD V+ + AFHHAGLT EER+I+E
Sbjct: 503 TVLGQRLRTNLNPRAIAEVKQQLRDIPTGLDGVMSKAITYACAFHHAGLTTEERDIIEAS 562
Query: 294 YRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGIDTKGE 353
++ G L+VL ATSTL++GVNLPARRV+ R P G + Y QM GRAGR G DT GE
Sbjct: 563 FKAGALKVLVATSTLSSGVNLPARRVLIRSPLFGGKQMSSLTYRQMIGRAGRMGKDTLGE 622
Query: 354 SVLICKPQELKKVMGLLNESCPPLHSCLSEDLNGMTH---AILEVVAGGIVQTANDI--- 407
S+LIC + L+ P+ SCL D++G TH A+LEV++ G+ T DI
Sbjct: 623 SILICNEINARMGRDLVVSELQPITSCL--DMDGSTHLKRALLEVISSGVANTKEDIDFF 680
Query: 408 ------------HRK--------------------------FLEWNE--DTKLYSTTPLG 427
H K L+ NE +T +Y T LG
Sbjct: 681 VNCTLLSAQKAFHAKEKPPDEESDANYINDALDFLVEYEFVRLQRNEERETAVYVATRLG 740
Query: 428 RASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVDV---EPDWESYYERF 484
A SS+ P + LI+ A+L ++R FVL S+LH VYLVTP +V + DW Y +
Sbjct: 741 AACLASSMPPTDGLILFAELQKSRRSFVLESELHAVYLVTPYSVCYQLQDIDWLLYVHMW 800
Query: 485 VKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNSDDQTL 544
KLS + VG VGV + FL + G D + +
Sbjct: 801 EKLSSPMKKVGELVGVRDAFLYKALRGQ------------------------TKLDYKQM 836
Query: 545 RVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCERLGWHD 604
++ KRFY+AL L LV ETP+ V +K RGM+Q LQ+ A FA +V FC L W
Sbjct: 837 QIHKRFYIALALEELVNETPINVVVHKYKCHRGMLQSLQQMASTFAGIVTAFCNSLQWST 896
Query: 605 FEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEASIPELVKAL 664
+V++F++R+ FG+ ++++L IP + RARAL+ AG+ + + +A A EL K L
Sbjct: 897 LALIVSQFKDRLFFGIHRDLIDLMRIPDLSQKRARALFDAGITSLVELAGADPVELEKVL 956
Query: 665 FESSSW 670
+ S S+
Sbjct: 957 YNSISF 962
Score = 104 bits (259), Expect = 3e-20
Identities = 52/133 (39%), Positives = 78/133 (58%), Gaps = 1/133 (0%)
Query: 1210 DALRVNARDYFVPTQDNWLLLTADYSQIELRLMAHFSKDSTLIELLRKPDGDVFTMIAAR 1269
D + ++ R F+PT ++ LL+AD+ Q+E+R++AH S+D L+E++ K D+F IAA
Sbjct: 1802 DVVHISCRSPFMPTDESRCLLSADFCQLEMRILAHMSQDKALLEVM-KSSQDLFIAIAAH 1860
Query: 1270 WIGCPEVSVGSRQREQTKKMVYGILYGMGPNSLAEQMDCTSDEASERISNFKSTFPGVAS 1329
W E V R TK++ YGI+YGMG SLAE ++C+ EA F + G+
Sbjct: 1861 WNKIEESEVTQDLRNSTKQVCYGIVYGMGMRSLAESLNCSEQEARMISDQFHQAYKGIRD 1920
Query: 1330 WLHEAVAFCRSKG 1342
+ V F RSKG
Sbjct: 1921 YTTRVVNFARSKG 1933
Score = 47.0 bits (110), Expect = 0.005
Identities = 39/144 (27%), Positives = 57/144 (39%), Gaps = 54/144 (37%)
Query: 1445 STSQGSAADIIKIAMIKIYSEIFPGVDKLDSSSSVTAKFEMLRDRCRILLQVHDELVLEV 1504
ST QGSAADI K A++K+ I +KL + +++ +HDEL+ EV
Sbjct: 1966 STIQGSAADIAKNAILKMEKNIERYREKLALGDNSVD----------LVMHLHDELIFEV 2015
Query: 1505 DPSVVKEAALLLQTSMENAVSLLGLYSLNKLFFWPFLFGCRHKLVKVIEDLTVWSNHIFT 1564
K+ A +L +MEN V L
Sbjct: 2016 PTGKAKKIAKVLSLTMENCVKL-------------------------------------- 2037
Query: 1565 VYAYASAVPLNVKLKVGRTWGSLE 1588
+VPL VKL++GR+WG +
Sbjct: 2038 ------SVPLKVKLRIGRSWGEFK 2055
Score = 40.8 bits (94), Expect = 0.34
Identities = 43/186 (23%), Positives = 72/186 (38%), Gaps = 25/186 (13%)
Query: 1038 DMCIVAWILWPDEESSSSPNLDKEVKKRLSPEDAAAANQCGRWRNQMRKA--AHNGCCRR 1095
D + W+L PD+ + + + +PE AN CG R + R
Sbjct: 1563 DAKVANWLLQPDKTVNFL-----NMCQTFAPECTGLANLCGSGRGYSSYGLDTSSAILPR 1617
Query: 1096 VAQTRALCSVLWKL---------LVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCI 1146
+ C L L + + L++ +IE+P+ L MEL G +
Sbjct: 1618 IRTAIESCVTLHILQGQTENLSRIGNGDLLKFFHDIEMPIQLTLCQMELVGFPAQKQRLQ 1677
Query: 1147 QARKLLVKRLKQLEKEAYKLAGMTFSLSMPADIAKVLFEHLKLPIPDGKNKGKNHPSTGK 1206
Q + +V +K++E + Y+ G F+L +AKVL H K K +T +
Sbjct: 1678 QLYQRMVAVMKKVETKIYEQHGSRFNLGSSQAVAKVLGLH---------RKAKGRVTTSR 1728
Query: 1207 HCLDAL 1212
L+ L
Sbjct: 1729 QVLEKL 1734
>UniRef100_Q8TDG4 DNA helicase HEL308 [Homo sapiens]
Length = 1101
Score = 360 bits (923), Expect = 3e-97
Identities = 255/760 (33%), Positives = 384/760 (49%), Gaps = 131/760 (17%)
Query: 3 ILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPK---DTSVAVCTIEKANSL 59
+++LPYV+I EK L LG V Y G++G K S+ + TIEK +SL
Sbjct: 385 LMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKGRFPPTKRREKKSLYIATIEKGHSL 444
Query: 60 INRLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGS 119
+N L+E GR+ +G++V+DELHM+G+ RG LE+ L K+ Y SK++
Sbjct: 445 VNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMTLAKILYT-----SKTT-------- 491
Query: 120 SDKNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIY------ 173
QI+GMSAT+ NV + +LQA Y ++FRPV L+EY+K+ ++IY
Sbjct: 492 ----------QIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSKA 541
Query: 174 NKSMELSRTIP-KGAD-LGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKF 231
M SR + K +D L DPDH+V L EV+ S L+FC S+K CE+ A + KF
Sbjct: 542 ENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVI-PNYSCLVFCPSKKNCENVAEMICKF 600
Query: 232 L-KSFTVDINENNCEFADITSAINSLRKCPAG-LDPVLEETFPAGVAFHHAGLTVEEREI 289
L K + + CE I +L+ G L PVL+ T P GVA+HH+GLT +ER++
Sbjct: 601 LSKEYLKHKEKEKCE------VIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKL 654
Query: 290 VETCYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGID 349
+E Y G+L + T TSTLAAGVNLPARRVI R P + +F+ +Y QM GRAGR GID
Sbjct: 655 LEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGID 714
Query: 350 TKGESVLICKPQELKKVMGLLNESCPPLHSCLS----EDLNGMTHAILEVVAGGIVQTAN 405
T GES+LI + ++ ++V+ L+ + PL +C S E G+ L ++ I +
Sbjct: 715 TIGESILILQEKDKQQVLELITK---PLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLD 771
Query: 406 DIH------------------RKFLEWNEDTKLYST-----------------------T 424
DI+ + E ++ Y T T
Sbjct: 772 DIYHFMNGTFFGVQQKVLLKEKSLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHIT 831
Query: 425 PLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINV--DVEPDWESYYE 482
LGRASF ++ I+ DL + EG VL S LHL+YL TP ++ PDW Y+
Sbjct: 832 KLGRASFKGTIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFR 891
Query: 483 RFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNSDDQ 542
+F +LSP +Q+V +GV+E F+ + A G +G +
Sbjct: 892 QFSQLSPAEQNVAAILGVSESFIGKKASGQAIGKKVDK---------------------- 929
Query: 543 TLRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCERL-G 601
V R Y++ +L L++ET + V E F + RG +Q L F+S V FCE L
Sbjct: 930 --NVVNRLYLSFVLYTLLKETNIWTVSEKFNMPRGYIQNLLTGTASFSSCVLHFCEELEE 987
Query: 602 WHDFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEASIPELV 661
+ + L+ + ++++ V+AE++ L + V RA+ LY AG ++ + +A A+ LV
Sbjct: 988 FWVYRALLVELTKKLTYCVKAELIPLMEVTGVLEGRAKQLYSAGYKSLMHLANANPEVLV 1047
Query: 662 KALFESSSWGTEGSAQRSLQFGVAKKIKNGARKIVLDKAE 701
+ + L AK+I + A+ ++ +KAE
Sbjct: 1048 RTI-------------DHLSRRQAKQIVSSAKMLLHEKAE 1074
>UniRef100_UPI0000437A8D UPI0000437A8D UniRef100 entry
Length = 827
Score = 358 bits (919), Expect = 7e-97
Identities = 251/738 (34%), Positives = 379/738 (51%), Gaps = 115/738 (15%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPK---DTSVAVCTIEKANS 58
A+L+LPY+S+ EK L L V Y G++G K S+ + TIEK +S
Sbjct: 124 ALLILPYISLVQEKVRGLSSFGIELDFLVEEYAGSKGKFPPVKRRNKNSLYITTIEKGHS 183
Query: 59 LINRLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGG 118
L+N L+E RL +G++V+DELHM+GD RG +LE+ L+K+ Y +SKS+
Sbjct: 184 LVNSLIENDRLDNIGLVVVDELHMLGDGSRGAILEMTLSKILY-----MSKST------- 231
Query: 119 SSDKNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYNKSME 178
Q++GMSAT+ NV + +L+A Y FRPV L+EY+K+ +SIY +
Sbjct: 232 -----------QVIGMSATLGNVKDLQSFLRAENYTNNFRPVELKEYVKIKDSIYEVDPK 280
Query: 179 ------LSRTI--PKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAK 230
SR + + + DPDH++ L EV+ + QS LIFC+++K CE+ A + K
Sbjct: 281 EEACFTFSRLLNFKYSSGMQKMDPDHIIALATEVIPQ-QSCLIFCATKKNCENLAGMICK 339
Query: 231 FL-KSFTVDINENNCEFADITSAINSLRKCPAGLDPVLEETFPAGVAFHHAGLTVEEREI 289
+L K F I E A + + S L PVL++T P G+A+HH+GLT +ER++
Sbjct: 340 YLNKEF---IKHKEAEKAILLGELKSSGN--GSLCPVLQKTIPFGLAYHHSGLTSDERKL 394
Query: 290 VETCYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGID 349
VE Y G+L +LT TSTLAAG+NLPARRVI R P + DF+ ++Y QM GRAGR GID
Sbjct: 395 VEEAYSSGVLCLLTCTSTLAAGINLPARRVILRSPYVAADFLKRSQYKQMVGRAGRAGID 454
Query: 350 TKGESVLICKPQELKKVMGLLNESCPPLHSCLSEDLN----GMTHAILEVVAGGIVQTAN 405
GES+LI + +++ LL C P+ C S L+ G+ IL ++ I T
Sbjct: 455 AMGESILILQDKDINTAKKLL---CAPMEKCYSNLLHDGGRGLLSLILSLIGLKITTTVE 511
Query: 406 DI----------------------------------HRKFLEWNED---TKLYSTTPLGR 428
+ + +E + D + T LGR
Sbjct: 512 QVKDLMKGTFLGVQEAQVSPEKSLWDLTVESIQTLKQKNLIEVSSDENNQNILQITRLGR 571
Query: 429 ASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINV--DVEPDWESYYERFVK 486
A++ S+ ++ DLS+ EG +L S LHLVYLVTP ++ +PDW Y+ +F
Sbjct: 572 ATYKGSVDLSYCDVLYRDLSKGLEGLLLNSFLHLVYLVTPYDMVHQCKPDWMIYFRQFTN 631
Query: 487 LSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNSDDQTLRV 546
LS +Q + VGV E F+ R A G + S D + V
Sbjct: 632 LSAAEQKMATTVGVPESFVARKAAG----------------------QSVRKSVD--VVV 667
Query: 547 CKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCERL-GWHDF 605
R Y+AL+L L++ET + V E F++ RG VQ L +A F S V F E L + +
Sbjct: 668 VNRLYLALVLFSLLKETNLWIVSERFQLTRGFVQTLLSSASAFGSSVLHFTEELEEFWAY 727
Query: 606 EGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEA---SIPELVK 662
+ L+++ R+++ V+AE++ L + V RA+ LY AG +T +A A ++ + ++
Sbjct: 728 KALLSELTRRLTYCVQAELIPLMEVSGVLEHRAKQLYSAGYKTLSHLANADPQTLVQTIE 787
Query: 663 ALFESSSWGTEGSAQRSL 680
LF+ ++ SA+ L
Sbjct: 788 NLFKKQAYQIIASAKMLL 805
>UniRef100_UPI00001D076D UPI00001D076D UniRef100 entry
Length = 2778
Score = 301 bits (770), Expect = 1e-79
Identities = 175/384 (45%), Positives = 229/384 (59%), Gaps = 35/384 (9%)
Query: 2 AILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPKDTSVAVCTIEKANSLIN 61
A+ +LP+VS+ EK +L+ L + +G V Y G+ VAVCTIE+AN LIN
Sbjct: 209 ALFILPFVSVAKEKKYYLQSLFQEVGIKVDGYMGSTSPTGRFSSLDVAVCTIERANGLIN 268
Query: 62 RLLEEGRLSEMGI-----------------IVIDELHMVGDPKRGYLLELMLTKLRYAAG 104
RL+EE ++ +G +V+DELHM+GD RGYLLEL+LTK+ +
Sbjct: 269 RLIEENKMDLLGFLERCSFVKVNLETLVGTVVVDELHMLGDSHRGYLLELLLTKVCFVTR 328
Query: 105 EGISKSSDGEGSGGSSDKNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEE 164
+ S +D + A +QIVGMSAT+PN+ VA WL A LY T+FRPVPL E
Sbjct: 329 KSASCQADSASA--------LACAVQIVGMSATLPNLQLVASWLNAELYHTDFRPVPLLE 380
Query: 165 YIKVGNSIYNKSMELSRTIPKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCEST 224
IKVGNSIY+ SM+L R + G D DH+V LC E V++ SVL+FC S+K CE
Sbjct: 381 SIKVGNSIYDSSMKLVREFQPLLQVKG-DEDHIVSLCYETVRDNHSVLVFCPSKKWCEKV 439
Query: 225 ARHVAKFLKSF------TVDINENNCEFAD---ITSAINSLRKCPAGLDPVLEETFPAGV 275
A +A+ + V +E D + I+ L++ P+GLD VL+ T P GV
Sbjct: 440 ADIIAREFYNLHHQPEGLVKSSEFPPVILDQKSLLEVIDQLKRSPSGLDSVLKNTVPWGV 499
Query: 276 AFHHAGLTVEEREIVETCYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTR 335
AFHHAGLT EER+I+E +R+GL+RVL ATSTL++GVNLPARRVI R P G +D
Sbjct: 500 AFHHAGLTFEERDIIEGAFRQGLIRVLAATSTLSSGVNLPARRVIIRTPVFGGQPLDILT 559
Query: 336 YMQMAGRAGRTGIDTKGESVLICK 359
Y QM GRAGR G+DT VL K
Sbjct: 560 YKQMVGRAGRKGVDTMALVVLSIK 583
Score = 159 bits (402), Expect = 7e-37
Identities = 113/362 (31%), Positives = 170/362 (46%), Gaps = 74/362 (20%)
Query: 352 GESVLICKPQELKKVMGLLNESCPPLHSCLS---EDLNGMTHAILEVVAGGIVQTANDIH 408
GES+L+CK E K + LL S P+HSCL E + M AILE++ G+ T+ D+
Sbjct: 664 GESILVCKNSEKSKGIALLQGSLEPVHSCLQSQGEVTSTMIRAILEIIVSGVASTSQDMQ 723
Query: 409 ---------------RKFLEWNEDT------------------------------KLYST 423
++ ++ N D K+Y
Sbjct: 724 TYAACTFLAADVKEGKQGIQRNRDDVQRGAVDACVTWLLENEFIQAAEPSDGTGGKVYHP 783
Query: 424 TPLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTPINVD-VEPDWESYYE 482
T LG A+ SSL P ++L + ADL RA +GFVL +DLH+VYLVTP+ D DW ++
Sbjct: 784 THLGSATLSSSLSPTDTLDIFADLQRAMKGFVLENDLHIVYLVTPVFEDWTSIDWYRFFC 843
Query: 483 RFVKLSPLDQSVGNRVGVTEPFLMRMAHGVPMGSNKSRWSNNKRQNQHGMSSGIVNSDDQ 542
+ KL + V VGV E FL R G + + + QH +
Sbjct: 844 LWEKLPTSMKRVAELVGVEEGFLARCVKGKVVA---------RTERQH-----------R 883
Query: 543 TLRVCKRFYVALILSLLVQETPVGEVCEAFKVARGMVQGLQENAGRFASMVAVFCERLGW 602
+ + KR S +Q E+ + + RG +Q LQ++A +A M+ VF RLGW
Sbjct: 884 QMAIHKRQ-----ASRSLQLPQAREINQKYGCNRGQIQSLQQSAAVYAGMITVFSNRLGW 938
Query: 603 HDFEGLVAKFQNRVSFGVRAEVVELTTIPYVKGSRARALYKAGLRTPLAIAEASIPELVK 662
H+ E L+++FQ R++FG++ E+ +L + + RAR LY +G T +A A E+
Sbjct: 939 HNMELLLSQFQKRLTFGIQRELCDLIRVSSLNAQRARFLYASGFLTVADLARADTVEVEA 998
Query: 663 AL 664
AL
Sbjct: 999 AL 1000
Score = 72.4 bits (176), Expect = 1e-10
Identities = 86/352 (24%), Positives = 128/352 (35%), Gaps = 105/352 (29%)
Query: 1261 DVFTMIAARWIGCPEVSVGSRQREQTKKMVYGILYGMGPNSLAEQMDCTSDEASERISNF 1320
DVF IAA W +VG R+Q K++ YGI+YGMG SL EQM ++A+ I +F
Sbjct: 2508 DVFRSIAAEWKMIEPDAVGDNLRQQAKQICYGIIYGMGAKSLGEQMGIKENDAACYIDSF 2567
Query: 1321 KSTFPGVASWLHEAVAFCRSKG*GDLVPFLHFVYAFLLNLNYLWAVCNLIMCKYIHDPDM 1380
KS + G+ S + VC LI H+ +
Sbjct: 2568 KSRYKGLPSKVST-------------------------------LVCGLIPAHPAHEREG 2596
Query: 1381 *RLSREGNDFCQK*N----LAVVQKNQKLRGKLSIPFVRCNTLFSFSSKSGYVSLQAVSI 1436
SR D ++ + KN + G + R L + Y A
Sbjct: 2597 -ETSRSSVDPLRQQGINHFMRDTVKNCRRDGFVETILGRRRYLPGIKDNNPYHKAHAERQ 2655
Query: 1437 HVNIVFLPSTSQGSAADIIKIAMIKIYSEIFPGVDKLDSSSSVTAKFEMLRDRCRIL--- 1493
+N +T QGSAADI+K+A + I ++ S + + DR +L
Sbjct: 2656 AIN-----TTVQGSAADIVKVATVNIQKQLETFHPTFKSHGHRESMLQ--SDRAGLLPKR 2708
Query: 1494 ---------------LQVHDELVLEVDPSVVKEAALLLQTSMENAVSLLGLYSLNKLFFW 1538
LQ+HDEL+ EV V + A +++ ME A+ L
Sbjct: 2709 KVKGMFCPMRGGFFILQLHDELLYEVAEEDVVQVAQIVKNEMECAIKL------------ 2756
Query: 1539 PFLFGCRHKLVKVIEDLTVWSNHIFTVYAYASAVPLNVKLKVGRTWGSLEPF 1590
+V L VK+K+G +WG L+ F
Sbjct: 2757 --------------------------------SVKLKVKVKIGASWGELKDF 2776
Score = 60.1 bits (144), Expect = 5e-07
Identities = 35/89 (39%), Positives = 53/89 (59%), Gaps = 1/89 (1%)
Query: 1109 LLVSEKLVEALMEIEIPLVNVLADMELWGIGVDLEGCIQARKLLVKRLKQLEKEAYKLAG 1168
+L E L + ++E+P LA +EL GIG C + ++ +L +E +AY+LAG
Sbjct: 2190 MLQKENLHDIFCKVEMPSQYCLALLELNGIGFSTAECETQKHIMQAKLDAIETQAYQLAG 2249
Query: 1169 MTFSLSMPADIAKVLFEHLKLPIPDGKNK 1197
+FS + DIA+VLF LKLP P+G+ K
Sbjct: 2250 HSFSFTSADDIAQVLFLELKLP-PNGEMK 2277
>UniRef100_UPI00001802CC UPI00001802CC UniRef100 entry
Length = 510
Score = 289 bits (739), Expect = 6e-76
Identities = 194/497 (39%), Positives = 276/497 (55%), Gaps = 50/497 (10%)
Query: 3 ILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPK---DTSVAVCTIEKANSL 59
+L+LPYV+I EK L LG V Y G++G K S+ + TIEK +SL
Sbjct: 47 LLILPYVAIVQEKISSLSSFGIELGFFVEEYAGSKGRFPPIKRREKKSLYIATIEKGHSL 106
Query: 60 INRLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGS 119
+N L+E GR+ +G++V+DELHM+G+ RG LE+ L K+ Y SK++
Sbjct: 107 VNALIETGRMGTLGLVVVDELHMIGEGSRGATLEMTLAKVLYT-----SKTT-------- 153
Query: 120 SDKNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYN----- 174
QI+GMSAT+ NV + +L+A Y ++FRPV L+E++KV ++IY
Sbjct: 154 ----------QIIGMSATLNNVEDLQAFLKAEYYTSQFRPVELKEFLKVNDTIYEVDSRA 203
Query: 175 -KSMELSRTIP-KGAD-LGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKF 231
M SR + K +D L DPD +V L EV+ S L+FC S+K CE+ A + KF
Sbjct: 204 VDGMTFSRLLNYKYSDALKKVDPDRLVALVTEVI-PNYSCLVFCPSKKNCENVAEMLCKF 262
Query: 232 LKSFTVDINENNCEFADITSAINSLRKCPAG-LDPVLEETFPAGVAFHHAGLTVEEREIV 290
L ++ E + I SLR G + PVL+ T P GVA+HH+GLT +ER+++
Sbjct: 263 LSRDYLNHREE-----EKGELIKSLRNVGHGKVCPVLKRTIPFGVAYHHSGLTSDERKLL 317
Query: 291 ETCYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGIDT 350
E Y G+L + T TSTLAAGVNLPARRVI R P + F+ +Y QM GRAGR GIDT
Sbjct: 318 EEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVANTFLKRNQYKQMIGRAGRAGIDT 377
Query: 351 KGESVLICKPQELKKVMGLLNESCPPLHSCLSEDL-NGMTHAILEVVA-GGIVQTANDIH 408
GES+L+ + ++ ++V+GL+N HS L E+ G+ L ++ G++Q D H
Sbjct: 378 AGESILLLQEKDKQQVLGLINGPLEDCHSHLVEEFTKGIQSLFLSLIGLKGLLQ--KDSH 435
Query: 409 RKFLEWNEDTKLYSTTPLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYLVTP 468
E + T LG+ASF ++ + DL + EG VL S LHLVYL TP
Sbjct: 436 G---SPEESRCHFRITKLGQASFKGAIDLTYCDTLYRDLKKGLEGLVLESLLHLVYLTTP 492
Query: 469 INV--DVEPDWESYYER 483
++ EPDW Y+ +
Sbjct: 493 YDLAAQSEPDWMVYFRQ 509
>UniRef100_Q8R4K9 DNA helicase HEL308 [Mus musculus]
Length = 527
Score = 285 bits (730), Expect = 6e-75
Identities = 189/500 (37%), Positives = 274/500 (54%), Gaps = 54/500 (10%)
Query: 3 ILVLPYVSICTEKAEHLEKLLEPLGKHVRSYYGNQGGGSLPK---DTSVAVCTIEKANSL 59
+++LPYV+I EK L LG V Y G++G K S+ + TIEKA+SL
Sbjct: 47 LMILPYVAIVQEKISSLSSFGIELGFFVEEYAGSKGRFPPIKRREKKSLYIATIEKAHSL 106
Query: 60 INRLLEEGRLSEMGIIVIDELHMVGDPKRGYLLELMLTKLRYAAGEGISKSSDGEGSGGS 119
+N L+E RLS +G++V+DELHM+G+ RG +LE+ K+ Y SK++
Sbjct: 107 VNALIETSRLSTLGLVVVDELHMIGEGSRGAILEMTQAKVLYT-----SKTT-------- 153
Query: 120 SDKNDPAQGLQIVGMSATMPNVAAVADWLQAALYQTEFRPVPLEEYIKVGNSIYN----- 174
QI+GMSAT+ NV + +L+A Y ++FRPV L+E++KV ++IY
Sbjct: 154 ----------QIIGMSATLNNVEDLQAFLKAEYYTSQFRPVELKEFLKVNDTIYEVDSQA 203
Query: 175 -KSMELSRTI--PKGADLGGKDPDHVVELCNEVVQEGQSVLIFCSSRKGCESTARHVAKF 231
M SR + L DPD +V L E + S L+FC S+K CE+ A + KF
Sbjct: 204 ADGMTFSRLLSYKYSEALKKMDPDRLVALVTEAI-PNYSCLVFCPSKKNCENVAEMLCKF 262
Query: 232 L-KSFTVDINENNCEFADITSAINSLRKCPAG-LDPVLEETFPAGVAFHHAGLTVEEREI 289
L K + + CE I SLR G + PVL+ T P G+A+HH+GLT EER++
Sbjct: 263 LSKDYLNHREKEKCE------VIKSLRNIGNGKVCPVLKRTVPFGIAYHHSGLTSEERKL 316
Query: 290 VETCYRKGLLRVLTATSTLAAGVNLPARRVIFRQPRIGCDFIDGTRYMQMAGRAGRTGID 349
+E Y G+L +LT TSTLAAGVNLPARRVI R P + F+ +Y QM GRAGR GID
Sbjct: 317 LEEAYSTGVLCLLTCTSTLAAGVNLPARRVILRAPYVANTFLKRNQYKQMVGRAGRAGID 376
Query: 350 TKGESVLIC----KPQELKKVMGLLNESCPPLHSCLSEDLNGMTHAILEVVAGGIVQTAN 405
T GES+L+ K Q L+ + G L C L ++ + + +++ + G++Q +
Sbjct: 377 TAGESILLLQEKDKQQVLELISGPLETCCSHLVEEFTKGIQALFLSLIGLKEKGLLQKDS 436
Query: 406 DIHRKFLEWNEDTKLYSTTPLGRASFGSSLCPEESLIVLADLSRAREGFVLASDLHLVYL 465
+ LE + + T LG+ASF ++ + DL + EG VL S LHL+YL
Sbjct: 437 CGDNEGLECH-----FRITKLGQASFKGAIDLAYCDTLYRDLKKGLEGLVLESLLHLIYL 491
Query: 466 VTPINV--DVEPDWESYYER 483
TP ++ EPDW Y+++
Sbjct: 492 TTPYDLAAQSEPDWMVYFKQ 511
Database: uniref100
Posted date: Jan 5, 2005 1:24 AM
Number of letters in database: 848,049,833
Number of sequences in database: 2,790,947
Lambda K H
0.320 0.136 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,619,724,583
Number of Sequences: 2790947
Number of extensions: 110175697
Number of successful extensions: 275614
Number of sequences better than 10.0: 1815
Number of HSP's better than 10.0 without gapping: 1224
Number of HSP's successfully gapped in prelim test: 591
Number of HSP's that attempted gapping in prelim test: 269188
Number of HSP's gapped (non-prelim): 4229
length of query: 1603
length of database: 848,049,833
effective HSP length: 141
effective length of query: 1462
effective length of database: 454,526,306
effective search space: 664517459372
effective search space used: 664517459372
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 82 (36.2 bits)
Medicago: description of AC127429.13