BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC124963.22 + phase: 0 /pseudo
(516 letters)
Database: uniref100
2,790,947 sequences; 848,049,833 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef100_Q8W041 Dihydrofolate synthetase /folylpolyglutamate sy... 307 4e-82
UniRef100_Q9FN53 Folylpolyglutamate synthase-like protein [Arabi... 286 1e-75
UniRef100_Q7Y203 Putative folylpolyglutamate synthase [Arabidops... 158 4e-37
UniRef100_UPI00002E53A5 UPI00002E53A5 UniRef100 entry 114 5e-24
UniRef100_Q9WY13 Folylpolyglutamate synthase/dihydrofolate synth... 114 7e-24
UniRef100_Q92BG3 FolC protein [Listeria innocua] 114 9e-24
UniRef100_Q6DKZ3 Dihydrofolate/folylpolyglutamate synthase [Toxo... 112 3e-23
UniRef100_Q8Y6Y0 FolC protein [Listeria monocytogenes] 111 6e-23
UniRef100_Q7RHU7 Dihydrofolate synthase/folylpolyglutamate synth... 111 6e-23
UniRef100_Q05865 Folylpolyglutamate synthase [Bacillus subtilis] 111 6e-23
UniRef100_UPI000046B789 UPI000046B789 UniRef100 entry 110 7e-23
UniRef100_Q71ZB7 Folylpolyglutamate synthase [Listeria monocytog... 106 1e-21
UniRef100_Q8DMD0 Folylpolyglutamate synthase [Synechococcus elon... 105 2e-21
UniRef100_UPI0000299514 UPI0000299514 UniRef100 entry 105 4e-21
UniRef100_Q6A9I9 Folylpolyglutamate synthase [Propionibacterium ... 104 7e-21
UniRef100_Q7NLP7 Folylpolyglutamate synthase [Gloeobacter violac... 103 9e-21
UniRef100_Q64S09 Folylpolyglutamate synthase [Bacteroides fragilis] 103 1e-20
UniRef100_Q9K8G9 Folyl-polyglutamate synthetase [Bacillus halodu... 102 3e-20
UniRef100_Q9L1G4 Folylpolyglutamate synthase [Streptomyces coeli... 102 3e-20
UniRef100_Q97GG9 Folylpolyglutamate synthase [Clostridium acetob... 102 3e-20
>UniRef100_Q8W041 Dihydrofolate synthetase /folylpolyglutamate synthetase
[Arabidopsis thaliana]
Length = 530
Score = 307 bits (787), Expect = 4e-82
Identities = 166/284 (58%), Positives = 206/284 (72%), Gaps = 25/284 (8%)
Query: 2 RSVRTLCSHREDSEMKDLVDYIDSLKNYEKYGVPTGAGTDSNDGFDLGRMRRLLDRFGNP 61
R++ T+ S ED E++D V +++SLKNYEK GVP GAGTDS+DGFDLGRM+RL+ R NP
Sbjct: 32 RNLSTISS-TEDPELRDFVGFLESLKNYEKSGVPKGAGTDSDDGFDLGRMKRLMLRLRNP 90
Query: 62 HSKFKTE----------------------GYSVGCYSSPHIQTIRERILGRSGDPVSAKL 99
H K+K GYSVGCYSSPHI +I+ERI +G+PVSA
Sbjct: 91 HYKYKVVHVAGTKGKGSTSAFLSNILRAGGYSVGCYSSPHILSIKERI-SCNGEPVSAST 149
Query: 100 LNNLFHRIKQDLDQAIKEENGCISHFEVFTAMAFILFADEKVDIAVIEAGLGGARDATNI 159
LN+LF+ +K L+Q+I+EENG +SHFE+ T +AF LF E VDIAVIEAGLGGARDATN+
Sbjct: 150 LNDLFYSVKPILEQSIQEENGSLSHFEILTGIAFSLFEKENVDIAVIEAGLGGARDATNV 209
Query: 160 ISSSGLAAAVITTVGEEHLAALGGSLESIAMAKAGIIKQGCPLVLGGPFLPHIEYIIREK 219
I SS LAA+VITT+GEEH+AALGGSLESIA AK+GIIK G P+VLGGPFLPHIE I+R K
Sbjct: 210 IESSNLAASVITTIGEEHMAALGGSLESIAEAKSGIIKHGRPVVLGGPFLPHIEGILRSK 269
Query: 220 AVNMDSPVVSASDSGNNLAVKSFSILNG-KPCQICDIEIQTVKD 262
A ++ S V+ AS+ G++ ++K NG CQ CDI IQ KD
Sbjct: 270 AASVSSSVILASNIGSSSSIKGIINKNGIGLCQSCDIVIQNEKD 313
Score = 117 bits (293), Expect = 8e-25
Identities = 72/161 (44%), Positives = 96/161 (58%), Gaps = 29/161 (18%)
Query: 357 AHTKESAKALMNTIKMASPKARLAFVVAMASDKDHAGFAREILSDAYVKTVILTEAAIAG 416
AHTKESA+AL IK P+ RL FVVAMASDKDH FA+E+LS + VILTEA I G
Sbjct: 395 AHTKESARALKEMIKKDFPEKRLVFVVAMASDKDHVSFAKELLSGLKPEAVILTEADIGG 454
Query: 417 AVTRTAPASLLRDSWIKASEELGTDICHDGMTEYRELFKEQPVSSESNLTDGKTILATES 476
R+ +S L++SWIKA++ELG S ++ KT+L +
Sbjct: 455 GKIRSTESSALKESWIKAADELG--------------------SRSMEASENKTVLGS-- 492
Query: 477 SLKDCLRMANEIL--NRRRDEKGVIVITGSLHIVSSVLASL 515
L++A +IL + + G++++TGSLHIVSSVLASL
Sbjct: 493 -----LKLAYKILSDDTTSSDSGMVIVTGSLHIVSSVLASL 528
>UniRef100_Q9FN53 Folylpolyglutamate synthase-like protein [Arabidopsis thaliana]
Length = 480
Score = 286 bits (731), Expect = 1e-75
Identities = 210/556 (37%), Positives = 292/556 (51%), Gaps = 132/556 (23%)
Query: 2 RSVRTLCSHREDSEMKDLVDYIDSLKNYEKYGVPTGAGTDSNDGFDLGRMRRLLDRFGNP 61
R++ T+ S ED E++D V +++SLKNYEK GVP GAGTDS+DGFDLGRM+RL+ R NP
Sbjct: 13 RNLSTISS-TEDPELRDFVGFLESLKNYEKSGVPKGAGTDSDDGFDLGRMKRLMLRLRNP 71
Query: 62 HSKFKTE----------------------GYSVGCYSSPHIQTIRERILGRSGDPVSAKL 99
H K+K GYSVGCYSSPHI +I+ERI +G+PVSA
Sbjct: 72 HYKYKVVHVAGTKGKGSTSAFLSNILRAGGYSVGCYSSPHILSIKERI-SCNGEPVSAST 130
Query: 100 LNNLFHRIKQDLDQAIKEENGCISHFEVFTAMAFILFADEKVDIAVIEAGLGGARDATNI 159
LN+LF+ +K L+Q+I+EENG +SHFE+ T +AF LF E VDIAVIEAGLGGARDATN+
Sbjct: 131 LNDLFYSVKPILEQSIQEENGSLSHFEILTGIAFSLFEKENVDIAVIEAGLGGARDATNV 190
Query: 160 ISSSGLAAAVITTVGEEHLAALGGSLESIAMAKAGIIKQGCPLVLGGPFLPHIEYIIREK 219
I SS LAA+VITT+ GGPFLPHIE I+R K
Sbjct: 191 IESSNLAASVITTI-------------------------------GGPFLPHIEGILRSK 219
Query: 220 AVNMDSPVVSASDSGNNLAVKSFSILNG-KPCQICDIEIQTVK---------DLKLAMDP 269
A ++ S V+ AS+ G++ ++K NG CQ CDI IQ K D+ L M
Sbjct: 220 AASVSSSVILASNIGSSSSIKGIINKNGIGLCQSCDIVIQNEKDDQPIVELSDVNLRMLG 279
Query: 270 DPRCACGPVSCMI*SC----KCLVLTN----FKMQQLLLV*HSVFVI*VDGEFLMNL*GV 321
+ + + C C +T+ ++ L+ S F+ + E L+ L G
Sbjct: 280 HHQLQNAVTATCVSLCLRDQGCGRVTDEAIRIGLENTRLLGRSQFLTPKEAETLL-LPGA 338
Query: 322 G*SVHTSLEGVSS*NLKKPRPWDFLEQQYCLI*SVAHTKESAKALMNTIKMASPKARLAF 381
+ + S+ LK+ DF E++ + + MAS K ++F
Sbjct: 339 TVLLDGAHTKESARALKEMIKKDFPEKRLVFV----------------VAMASDKDHVSF 382
Query: 382 VVAMASDKDHAGFAREILSDAYVKTVILTEAAIAGAVTRTAPASLLRDSWIKASEELGTD 441
A+E+LS + VILTEA I G R+ +S+L++SWIKA++ELG
Sbjct: 383 -------------AKELLSGLKPEAVILTEADIGGGKIRSTESSVLKESWIKAADELG-- 427
Query: 442 ICHDGMTEYRELFKEQPVSSESNLTDGKTILATESSLKDCLRMANEIL--NRRRDEKGVI 499
S ++ KT+L + L++A +IL + + G++
Sbjct: 428 ------------------SRSMEASENKTVLGS-------LKLAYKILSDDTTSSDSGMV 462
Query: 500 VITGSLHIVSSVLASL 515
++TGSLHIVSSVLASL
Sbjct: 463 IVTGSLHIVSSVLASL 478
>UniRef100_Q7Y203 Putative folylpolyglutamate synthase [Arabidopsis thaliana]
Length = 318
Score = 158 bits (399), Expect = 4e-37
Identities = 131/373 (35%), Positives = 191/373 (51%), Gaps = 77/373 (20%)
Query: 163 SGLAAAVITTVGEEHLAALGGSLESIAMAKAGIIKQGCPLVLGGPFLPHIEYIIREKAVN 222
S LAA+VITT+GEEH+AALGGSLESIA AK+GIIK G P+VLGGPFLPHI+ I+R KA +
Sbjct: 1 SSLAASVITTIGEEHMAALGGSLESIAEAKSGIIKHGRPVVLGGPFLPHIKGILRSKAAS 60
Query: 223 MDSPVVSASDSGNNLAVKSFSILNG-KPCQICDIEIQTVK---------DLKLAMDPDPR 272
+ S V+ AS+ G++ ++K NG CQ CDI IQ K D+ L M +
Sbjct: 61 VSSSVILASNIGSSSSIKGIINKNGIGLCQSCDIVIQNEKDDQPIVELSDVNLRMLGHHQ 120
Query: 273 CACGPVSCMI*SC----KCLVLTN----FKMQQLLLV*HSVFVI*VDGEFLMNL*GVG*S 324
+ + C C +T+ ++ L+ S F+ + E L+ L G
Sbjct: 121 LQNAVTATCVSLCLRDQGCGRVTDEAIRIGLENTRLLGRSQFLTPKEAETLL-LPGATVL 179
Query: 325 VHTSLEGVSS*NLKKPRPWDFLEQQYCLI*SVAHTKESAKALMNTIKMASPKARLAFVVA 384
+ + S+ LK+ DF E++ + + MAS K ++F
Sbjct: 180 LDGAHTKESARALKEMIKKDFPEKRLVFV----------------VAMASDKDHVSF--- 220
Query: 385 MASDKDHAGFAREILSDAYVKTVILTEAAIAGAVTRTAPASLLRDSWIKASEELGTDICH 444
A+E+LS + VILTEA I G R+ +S+L++SWIKA++ELG
Sbjct: 221 ----------AKELLSGLKPEAVILTEADIGGGKIRSTESSVLKESWIKAADELG----- 265
Query: 445 DGMTEYRELFKEQPVSSESNLTDGKTILATESSLKDCLRMANEIL--NRRRDEKGVIVIT 502
S ++ KT+L + L++A +IL + + G++++T
Sbjct: 266 ---------------SRSMEASENKTVLGS-------LKLAYKILSDDTTSSDSGMVIVT 303
Query: 503 GSLHIVSSVLASL 515
GSLHIVSSVLASL
Sbjct: 304 GSLHIVSSVLASL 316
>UniRef100_UPI00002E53A5 UPI00002E53A5 UniRef100 entry
Length = 236
Score = 114 bits (286), Expect = 5e-24
Identities = 77/247 (31%), Positives = 124/247 (50%), Gaps = 33/247 (13%)
Query: 1 MRSVRTLCSHREDSEMKDLVDYIDSLKNYEKYGVPTGAGTDSNDGFDLGRMRRLLDRFGN 60
M++ T ++RE ++ ++++ + +NYE+ G G S F L MR LL R G+
Sbjct: 1 MQTDTTAQNYRESENYREAMEFLANRENYERGGA---RGVKS---FQLDSMRNLLRRLGD 54
Query: 61 PHSKFKT----------------------EGYSVGCYSSPHIQTIRERILGRSGDPVSAK 98
P + F +GY VG Y+SPH+ + ER + G P +
Sbjct: 55 PQNAFPIVHIAGTKGKGSTAAMISAAACEQGYRVGLYTSPHLHHVEERFVV-DGKPCTES 113
Query: 99 LLNNLFHRIKQDLDQAIKEENGCISHFEVFTAMAFILFADEKVDIAVIEAGLGGARDATN 158
L +L ++ ++ E ++FEV TA+A + FA + VD+AV+E G+GG D+TN
Sbjct: 114 QLADLLWEVRPFVEAMDHESGRGPTYFEVTTAVAMLYFAQQDVDLAVLEVGMGGRLDSTN 173
Query: 159 IISSSGLAAAVITTVGEEHLAALGGSLESIAMAKAGIIKQGCPLVLGGPFLPHIEYIIRE 218
+ +IT++ +H LG +L IA KAGIIK+G P V+ G P +IRE
Sbjct: 174 VCDP---VLTIITSISLDHTRELGDTLPLIAQEKAGIIKRGVP-VISGVVEPAARDVIRE 229
Query: 219 KAVNMDS 225
++ D+
Sbjct: 230 QSQENDA 236
>UniRef100_Q9WY13 Folylpolyglutamate synthase/dihydrofolate synthase [Thermotoga
maritima]
Length = 430
Score = 114 bits (285), Expect = 7e-24
Identities = 76/201 (37%), Positives = 109/201 (53%), Gaps = 29/201 (14%)
Query: 48 LGRMRRLLDRFGNPHSKFKT----------------------EGYSVGCYSSPHIQTIRE 85
L R+ LL + GNPH ++KT +GY VG Y SPH+ T RE
Sbjct: 23 LERISMLLSKLGNPHLEYKTIHIGGTNGKGSVANMVSNILVSQGYRVGSYYSPHLSTFRE 82
Query: 86 RILGRSGDPVSAKLLNNLFHRIKQDLDQAIKEENGCISHFEVFTAMAFILFADEKVDIAV 145
RI + + +S + + ++ ++ L++ KEE S FEV TAMAF+ FA++ VDIAV
Sbjct: 83 RIR-LNEEYISEEDVVKIYETMEPILNELDKEEIFSPSFFEVVTAMAFLYFAEKNVDIAV 141
Query: 146 IEAGLGGARDATNIISSSGLAAAVITTVGEEHLAALGGSLESIAMAKAGIIKQGCPLVLG 205
+E GLGG DATN++ + I TV +H LG ++E IA K+GIIK+ PLV G
Sbjct: 142 LEVGLGGRLDATNVVFP---LCSTIVTVDRDHEKTLGYTIEQIAWEKSGIIKERVPLVTG 198
Query: 206 ---GPFLPHIEYIIREKAVNM 223
L +E + R+K+ M
Sbjct: 199 ERKREALKVMEDVARKKSSRM 219
>UniRef100_Q92BG3 FolC protein [Listeria innocua]
Length = 429
Score = 114 bits (284), Expect = 9e-24
Identities = 69/166 (41%), Positives = 100/166 (59%), Gaps = 6/166 (3%)
Query: 63 SKFKTEGYSVGCYSSPHIQTIRERILGRSGDPVSAKLLNNLFHRIKQDLDQAIKEENGCI 122
S + GY G ++SP+I+T ERI +G PVS +++ +L +RIK ++ K G
Sbjct: 62 SSLEEAGYKTGTFTSPYIETFNERI-SVNGIPVSDQMIVDLANRIKPIAEELEKTVYGPP 120
Query: 123 SHFEVFTAMAFILFAD-EKVDIAVIEAGLGGARDATNIISSSGLAAAVITTVGEEHLAAL 181
S FE+ TAM F+ FA+ E +DI +IE GLGG D+TN+++ +VITT+G +H+ L
Sbjct: 121 SEFEIITAMMFLCFAEYESIDIGIIEVGLGGRLDSTNVLTP---LISVITTIGMDHMEFL 177
Query: 182 GGSLESIAMAKAGIIKQGCPLVLGGPFLPHIEYIIREKAVNMDSPV 227
G S+E IA KAGIIK G P V+ G + +I AV +S V
Sbjct: 178 GNSIEQIAGEKAGIIKPGIP-VISGVIQKEAQEVIINNAVRNNSNV 222
>UniRef100_Q6DKZ3 Dihydrofolate/folylpolyglutamate synthase [Toxoplasma gondii]
Length = 553
Score = 112 bits (279), Expect = 3e-23
Identities = 75/198 (37%), Positives = 107/198 (53%), Gaps = 15/198 (7%)
Query: 68 EGYSVGCYSSPHIQTIRERILGRSGDPVSAKLLNNLFHRIKQDLDQAIKEENGCISHFEV 127
+GY VG Y+SPHI + RERI S + + + +L+HR+ Q Q E ++ FEV
Sbjct: 70 KGYKVGTYTSPHILSFRERIRVDS-QMIPEEDVVSLYHRVTQTAKQMGVE----LTFFEV 124
Query: 128 FTAMAFILFADEKVDIAVIEAGLGGARDATNIISSSGLAAAVITTVGEEHLAALGGSLES 187
T MAF+ F+ ++VD AVIE GLGG DATNI+ S VIT++G +H+ LG +L+
Sbjct: 125 TTQMAFLYFSQQEVDWAVIETGLGGRLDATNIVDSP--RCTVITSIGWDHMNVLGDTLDR 182
Query: 188 IAMAKAGIIKQGCPLVLGGPFLPHIEYIIREKAVNMDSPVVSASDSGNNLAVKSFSILNG 247
IA KAG+IK PLVLG H + + V D V A G + ++
Sbjct: 183 IAQEKAGVIKAKTPLVLGPTAAVHPCFRQKAACVGADVMEVQAEPRGEDFEDENI----- 237
Query: 248 KPCQICDIEIQTVKDLKL 265
+IC + ++ V L L
Sbjct: 238 ---RICRVVVENVLRLDL 252
>UniRef100_Q8Y6Y0 FolC protein [Listeria monocytogenes]
Length = 429
Score = 111 bits (277), Expect = 6e-23
Identities = 68/179 (37%), Positives = 105/179 (57%), Gaps = 14/179 (7%)
Query: 69 GYSVGCYSSPHIQTIRERILGRSGDPVSAKLLNNLFHRIKQDLDQAIKEENGCISHFEVF 128
GY G ++SP+I+ ERI +G+P+S +++ +L +RIK ++ K G S FE+
Sbjct: 68 GYKAGTFTSPYIEVFNERI-SVNGEPISDEMIVSLANRIKPIAEELEKTVYGPPSEFEII 126
Query: 129 TAMAFILFADE-KVDIAVIEAGLGGARDATNIISSSGLAAAVITTVGEEHLAALGGSLES 187
TAM F+ FAD +DI +IE GLGG D+TNI+ +VITT+G +H+ LG ++E
Sbjct: 127 TAMMFLCFADYVSIDIGIIEVGLGGRLDSTNILVP---LVSVITTIGMDHMEFLGDTIEQ 183
Query: 188 IAMAKAGIIKQGCPLVLGGPFLPHIEYIIREKAVNMDSPVVSASDSGNNLAVKSFSILN 246
IA KAGIIK G P+V G I+++A + + + + + S K+FS+ N
Sbjct: 184 IASEKAGIIKPGIPVVSGA---------IQKEAQEVIAEIATKNKSNVTQLNKAFSMHN 233
>UniRef100_Q7RHU7 Dihydrofolate synthase/folylpolyglutamate synthase [Plasmodium
yoelii yoelii]
Length = 491
Score = 111 bits (277), Expect = 6e-23
Identities = 73/228 (32%), Positives = 118/228 (51%), Gaps = 36/228 (15%)
Query: 48 LGRMRRLLDRFGNPHSKFKT----------------------EGYSVGCYSSPHIQTIRE 85
LG ++L + FGNP+ +KT + Y VG +SSPHI ++RE
Sbjct: 25 LGSTKKLSELFGNPYKNYKTIHVAGTNGKGSVCHKIYLGLKLKKYKVGIFSSPHIFSLRE 84
Query: 86 RILGRSGDPVSAKLLNNLFHRIKQDLDQAIKEENGCISHFEVFTAMAFILFADEKVDIAV 145
RI+ + +P+S N+L + + +A K+ N + FE+ T +AFI F+++ VD AV
Sbjct: 85 RII-INDEPISE---NDLIALVNEVFKKA-KKINASPTFFEIITLVAFIYFSNQNVDYAV 139
Query: 146 IEAGLGGARDATNIISSSGLAAAVITTVGEEHLAALGGSLESIAMAKAGIIKQGCPLVLG 205
IE GLGG DATNI+ L +IT++G +HL LG L I K GI K+ +++G
Sbjct: 140 IETGLGGRLDATNILEKPEL--VIITSIGYDHLNILGNDLNQICNEKIGIFKKDAQVIIG 197
Query: 206 GPFLPHIEYIIREKAVNMDSPVV-------SASDSGNNLAVKSFSILN 246
++ + K +N + +V + ++ +A++S ILN
Sbjct: 198 PSVSIYVNVFEKAKELNCNMHIVPPEPRGETYNEENTRIAIESLKILN 245
>UniRef100_Q05865 Folylpolyglutamate synthase [Bacillus subtilis]
Length = 430
Score = 111 bits (277), Expect = 6e-23
Identities = 76/226 (33%), Positives = 115/226 (50%), Gaps = 38/226 (16%)
Query: 31 KYGVPTGAGTDSNDGFDLGRMRRLLDRFGNPHSKFKT----------------------E 68
K+GV G LGRM++L+ R G+P K +
Sbjct: 17 KFGVKPG----------LGRMKQLMARLGHPEKKIRAFHVAGTNGKGSTVAFIRSMLQEA 66
Query: 69 GYSVGCYSSPHIQTIRERILGRSGDPVSAKLLNNLFHRIKQDLDQAIKEENGCISHFEVF 128
GY+VG ++SP+I T ERI +G P+S + L +++K ++ + E G + FE+
Sbjct: 67 GYTVGTFTSPYIITFNERI-SVNGIPISDEEWTALVNQMKPHVEALDQTEYGQPTEFEIM 125
Query: 129 TAMAFILFAD-EKVDIAVIEAGLGGARDATNIISSSGLAAAVITTVGEEHLAALGGSLES 187
TA AF+ FA+ KVD + E GLGG D+TN++ VIT++G +H+ LG ++E
Sbjct: 126 TACAFLYFAEFHKVDFVIFETGLGGRFDSTNVVEP---LLTVITSIGHDHMNILGNTIEE 182
Query: 188 IAMAKAGIIKQGCPLVLGGPFLPHIEYIIREKAVNMDSPVVSASDS 233
IA KAGIIK+G P+V P +IR +A +P S D+
Sbjct: 183 IAGEKAGIIKEGIPIVT-AVTQPEALQVIRHEAERHAAPFQSLHDA 227
>UniRef100_UPI000046B789 UPI000046B789 UniRef100 entry
Length = 472
Score = 110 bits (276), Expect = 7e-23
Identities = 74/228 (32%), Positives = 117/228 (50%), Gaps = 36/228 (15%)
Query: 48 LGRMRRLLDRFGNPHSKFKT----------------------EGYSVGCYSSPHIQTIRE 85
LG ++L + FGNP+ +KT + Y VG +SSPHI ++RE
Sbjct: 25 LGCTKKLSELFGNPYKNYKTIHVAGTNGKGSVCHKIYLGLKLKNYKVGIFSSPHIFSLRE 84
Query: 86 RILGRSGDPVSAKLLNNLFHRIKQDLDQAIKEENGCISHFEVFTAMAFILFADEKVDIAV 145
RI+ +P+S N+L + + +A K+ N + FE+ T +AFI F+++ VD AV
Sbjct: 85 RIIVND-EPISE---NDLIALVNEVFKKA-KKINSSPTFFEIITLVAFIYFSNKNVDYAV 139
Query: 146 IEAGLGGARDATNIISSSGLAAAVITTVGEEHLAALGGSLESIAMAKAGIIKQGCPLVLG 205
IE GLGG DATNI+ L +IT++G +HL LG L I K GI K+ +++G
Sbjct: 140 IETGLGGRLDATNILEKPEL--VIITSIGYDHLNILGNDLNQICNEKIGIFKKDAQVIIG 197
Query: 206 GPFLPHIEYIIREKAVNMDSPVV-------SASDSGNNLAVKSFSILN 246
+I + K +N + +V + ++ +A++S ILN
Sbjct: 198 PSVSIYINVFEKAKELNCNIHIVPPEPRGETYNEENTRIAIESLKILN 245
>UniRef100_Q71ZB7 Folylpolyglutamate synthase [Listeria monocytogenes]
Length = 429
Score = 106 bits (265), Expect = 1e-21
Identities = 60/138 (43%), Positives = 88/138 (63%), Gaps = 5/138 (3%)
Query: 69 GYSVGCYSSPHIQTIRERILGRSGDPVSAKLLNNLFHRIKQDLDQAIKEENGCISHFEVF 128
GY G ++SP+I+ ERI +G+P+S +++ +L +RIK ++ K G S FE+
Sbjct: 68 GYRTGTFTSPYIEVFNERI-SINGEPISDEMIVSLANRIKPIAEELEKTIYGPPSEFEII 126
Query: 129 TAMAFILFADE-KVDIAVIEAGLGGARDATNIISSSGLAAAVITTVGEEHLAALGGSLES 187
TAM F+ FA+ +DI +IE GLGG D+TNI+ +VITT+G +H+ LG ++E
Sbjct: 127 TAMMFLCFAEYVSIDIGIIEVGLGGRLDSTNILVP---LISVITTIGMDHMEFLGDTIEQ 183
Query: 188 IAMAKAGIIKQGCPLVLG 205
IA KAGIIK G P+V G
Sbjct: 184 IASEKAGIIKPGIPVVSG 201
>UniRef100_Q8DMD0 Folylpolyglutamate synthase [Synechococcus elongatus]
Length = 424
Score = 105 bits (263), Expect = 2e-21
Identities = 66/166 (39%), Positives = 94/166 (55%), Gaps = 8/166 (4%)
Query: 63 SKFKTEGYSVGCYSSPHIQTIRERILGRSGDPVSAKLLNNLFHRIKQDLDQAIKEENGCI 122
S + GY G Y+SPH+ + ERI G+P++ ++ L +I+ L Q
Sbjct: 62 SVLRAAGYRTGRYTSPHLLSWCERICV-DGEPIAPEVFLTLIQQIEAVLPQVAYPP---- 116
Query: 123 SHFEVFTAMAFILFADEKVDIAVIEAGLGGARDATNIISSSGLAAAVITTVGEEHLAALG 182
S FEV TA A++ FA + VD+AV+E GLGG DATN+ +VIT++G +H LG
Sbjct: 117 SQFEVITAAAWLYFAQQGVDVAVMEVGLGGRLDATNVCQPP--LVSVITSIGWDHWQRLG 174
Query: 183 GSLESIAMAKAGIIKQGCPLVLGGPFLPHIEYIIREKAVNMDSPVV 228
SL +IA KAGI+KQG P V+ GP P + +I E+ + P V
Sbjct: 175 NSLGAIAGEKAGILKQGVPAVI-GPVPPEAKTVIAERLAALACPAV 219
>UniRef100_UPI0000299514 UPI0000299514 UniRef100 entry
Length = 290
Score = 105 bits (261), Expect = 4e-21
Identities = 73/208 (35%), Positives = 104/208 (49%), Gaps = 33/208 (15%)
Query: 47 DLGRMRRLLDRFGNPHSKFKT----------------------EGYSVGCYSSPHIQTIR 84
DL +R L + GNP ++ + GY VG Y+SPH++ R
Sbjct: 28 DLTNIRILAEHLGNPQNQLRCIHVAGTNGKGSTSHMLSSVLQEAGYKVGLYTSPHLKDFR 87
Query: 85 ERILGRSGDPVSAKLLNNLFHRIKQDLDQAIKEENGCISHFEVFTAMAFILFADEKVDIA 144
ERI +G +S + + + K E +S FE+ +AF FA EK DIA
Sbjct: 88 ERIK-INGQEISEEFVIEFIAKHKSFF------EANDMSFFEMTVGLAFDYFASEKTDIA 140
Query: 145 VIEAGLGGARDATNIISSSGLAAAVITTVGEEHLAALGGSLESIAMAKAGIIKQGCPLVL 204
+IE GLGG DATNII+ +VIT +G +H LG +LE+IA KAGIIK P+V+
Sbjct: 141 IIEVGLGGRLDATNIITP---LVSVITNIGLDHTQFLGNTLEAIAGEKAGIIKPNVPVVI 197
Query: 205 GGPFLPHIEYIIREKAVNMDSPVVSASD 232
G + + + KA ++P+ ASD
Sbjct: 198 -GEYTAETKPVFLAKAEENNAPIYLASD 224
>UniRef100_Q6A9I9 Folylpolyglutamate synthase [Propionibacterium acnes]
Length = 481
Score = 104 bits (259), Expect = 7e-21
Identities = 76/214 (35%), Positives = 104/214 (48%), Gaps = 28/214 (13%)
Query: 45 GFDLGRMRRLLDRFGNPH----------------------SKFKTEGYSVGCYSSPHIQT 82
G L R R +LD GNP S ++ G VG Y SPH+
Sbjct: 21 GPGLDRERAVLDLLGNPQQACPVIQIAGTNGKGSTAIMVDSLLRSAGLRVGRYCSPHLVD 80
Query: 83 IRERILGRSGDPVSAKLLNNLFHRIKQ--DLDQAIKEENGCISHFEVFTAMAFILFADEK 140
+ ERI G PVS L + + +++ L A + ++ FEV TAMAF FAD
Sbjct: 81 VTERIC-IDGRPVSHDLFDETWRQVEPMVGLVDAQHIDGIEMTFFEVMTAMAFAAFADAP 139
Query: 141 VDIAVIEAGLGGARDATNIISSSGLAAAVITTVGEEHLAALGGSLESIAMAKAGIIKQGC 200
VD+AV+E GLGG DATN+ ++ AV+T V +H+ LG SL+ IA KAGIIK GC
Sbjct: 140 VDVAVVEVGLGGRWDATNVADAN---IAVVTPVAMDHMHILGDSLDKIAAEKAGIIKPGC 196
Query: 201 PLVLGGPFLPHIEYIIREKAVNMDSPVVSASDSG 234
V+ G ++ + A P++ D G
Sbjct: 197 TPVIAGQEAEAAPVLLAQCADAGVKPLLEGPDWG 230
>UniRef100_Q7NLP7 Folylpolyglutamate synthase [Gloeobacter violaceus]
Length = 413
Score = 103 bits (258), Expect = 9e-21
Identities = 78/239 (32%), Positives = 116/239 (47%), Gaps = 41/239 (17%)
Query: 22 YIDSLKNYEKYGVPTGAGTDSNDGFDLGRMRRLLDRFGNPHSKFK--------------- 66
Y+D L +K+GV G L R++ LL R G P F+
Sbjct: 6 YLDHL---QKFGVHLG----------LERIQALLKRLGEPQVAFQAVHVAGTNGKGSVCA 52
Query: 67 -------TEGYSVGCYSSPHIQTIRERILGRSGDPVSAKLLNNLFHRIKQDLDQAIKEEN 119
T GY G Y+SPH+ ERI G +S L ++K + + +
Sbjct: 53 YLSHILQTAGYRTGRYTSPHLLDWNERIW-IDGAFISDGALQACLAKVKASAEH-LPKSL 110
Query: 120 GCISHFEVFTAMAFILFADEKVDIAVIEAGLGGARDATNIISSSGLAAAVITTVGEEHLA 179
G + FE+ TA AF+ FA V++AV+E GLGG DATN+ A+VIT +G +H
Sbjct: 111 GEPTQFEIVTAAAFLHFAQSAVEVAVVEVGLGGRLDATNVFEQP--PASVITGIGLDHCD 168
Query: 180 ALGGSLESIAMAKAGIIKQGCPLVLGGPFLPHIEYIIREKAVNMDSPVVSASDSGNNLA 238
LG +L +IA KAGI++ GCPLV P P ++ EKA+ + V++ ++ + +A
Sbjct: 169 QLGSTLAAIAAEKAGILRSGCPLVC-APLAPEAMQVVTEKALAL-GVVITLAEPAHEVA 225
>UniRef100_Q64S09 Folylpolyglutamate synthase [Bacteroides fragilis]
Length = 458
Score = 103 bits (257), Expect = 1e-20
Identities = 72/198 (36%), Positives = 104/198 (52%), Gaps = 12/198 (6%)
Query: 66 KTEGYSVGCYSSPHIQTIRERILGRSGDPVSAKLLNNLFHRIKQDLDQAIKEENGCISHF 125
++ GY VG Y+SPH+ RERI +G+P+ + + I+ D + E S F
Sbjct: 69 QSAGYRVGLYTSPHLVDFRERIR-INGEPIPQEYV------IRFVEDHRLFFEPLHPSFF 121
Query: 126 EVFTAMAFILFADEKVDIAVIEAGLGGARDATNIISSSGLAAAVITTVGEEHLAALGGSL 185
E+ TAMAF FAD+ +D+AVIE GLGG D TNII ++IT + +H+ LG +L
Sbjct: 122 ELTTAMAFRYFADQHIDVAVIEVGLGGRLDCTNIIRPD---LSIITNISFDHMQFLGNTL 178
Query: 186 ESIAMAKAGIIKQGCPLVLGGPFLPHIEYIIREKAVNMDSPVVSASDSGNNLAVKSFSI- 244
IA KAGIIK+G P+V+ G + + KA M++PV A + F
Sbjct: 179 AQIATEKAGIIKRGIPVVV-GETTEETKPVFYRKAQEMEAPVTFAEEEQRLKGATKFKTR 237
Query: 245 LNGKPCQICDIEIQTVKD 262
+ KP Q D + T +
Sbjct: 238 ADRKPGQYTDHQPNTAAE 255
>UniRef100_Q9K8G9 Folyl-polyglutamate synthetase [Bacillus halodurans]
Length = 430
Score = 102 bits (254), Expect = 3e-20
Identities = 60/159 (37%), Positives = 97/159 (60%), Gaps = 5/159 (3%)
Query: 69 GYSVGCYSSPHIQTIRERILGRSGDPVSAKLLNNLFHRIKQDLDQAIKEENGCISHFEVF 128
GY+VG ++SP+I+ RERI + G+P+S++ L I +++ + + G + FEV
Sbjct: 66 GYNVGTFTSPYIEHFRERIAYK-GEPISSEELVRSCLNIIDVVEELKRTDLGSPTEFEVI 124
Query: 129 TAMAFILFADEKVDIAVIEAGLGGARDATNIISSSGLAAAVITTVGEEHLAALGGSLESI 188
T +AF FA DI ++E GLGG D+TNI++ ++IT++G +H+ LGG+LESI
Sbjct: 125 TVIAFDFFARVNPDIVLLEVGLGGRLDSTNIVTP---LLSIITSIGHDHMNVLGGTLESI 181
Query: 189 AMAKAGIIKQGCPLVLGGPFLPHIEYIIREKAVNMDSPV 227
A KAGIIK P ++ P +I++KA + +P+
Sbjct: 182 AYEKAGIIKPDIPAIVHVK-QPEAFRVIQDKANKVKAPL 219
>UniRef100_Q9L1G4 Folylpolyglutamate synthase [Streptomyces coelicolor]
Length = 444
Score = 102 bits (254), Expect = 3e-20
Identities = 59/155 (38%), Positives = 93/155 (59%), Gaps = 5/155 (3%)
Query: 73 GCYSSPHIQTIRERILGRSGDPVSAKLLNNLFHRIKQDLDQAIKEENGCISHFEVFTAMA 132
G Y+SPH+Q+I ERI G P+SA+ + IK ++ ++ +S FEV T MA
Sbjct: 72 GRYTSPHVQSITERI-SLDGAPISAERFIETYEDIKPYVEMVDAQQEYRLSFFEVLTGMA 130
Query: 133 FILFADEKVDIAVIEAGLGGARDATNIISSSGLAAAVITTVGEEHLAALGGSLESIAMAK 192
+ FAD VD+AV+E G+GG+ DATN+I AV+T + +H LGG+ IA+ K
Sbjct: 131 YAAFADAPVDVAVVEVGMGGSWDATNVIDGD---VAVVTPIDLDHTDRLGGTPGEIAVEK 187
Query: 193 AGIIKQGCPLVLGGPFLPHIEYIIREKAVNMDSPV 227
AGI+KQ ++L + + +++ KAV++++ V
Sbjct: 188 AGIVKQDATVILAQQPVDAAQVMLK-KAVDVNATV 221
>UniRef100_Q97GG9 Folylpolyglutamate synthase [Clostridium acetobutylicum]
Length = 431
Score = 102 bits (254), Expect = 3e-20
Identities = 70/184 (38%), Positives = 97/184 (52%), Gaps = 28/184 (15%)
Query: 45 GFDLG--RMRRLLDRFGNPHSKFKT----------------------EGYSVGCYSSPHI 80
G +LG R+ RLL+ GNPH K K GY VG Y+SP+I
Sbjct: 17 GINLGLERILRLLEILGNPHKKIKCIHVAGTNGKGSTTAMISQILIEAGYRVGMYTSPYI 76
Query: 81 QTIRERILGRSGDPVSAKLLNNLFHRIKQDLDQAIKEENGCISHFEVFTAMAFILFADEK 140
+ ERI + + +S L + ++ +D+ E + FE+ TA AF+ F +K
Sbjct: 77 EEFEERIQINNNN-ISKYDLCVIIEKVSDAVDKLKCEGIENPTEFEIITAAAFLYFCIKK 135
Query: 141 VDIAVIEAGLGGARDATNIISSSGLAAAVITTVGEEHLAALGGSLESIAMAKAGIIKQGC 200
VD AVIE GLGG DATN+I+ VIT++ +H+A LG +L IA KAGIIK+
Sbjct: 136 VDYAVIEVGLGGRFDATNVINP---ILTVITSISYDHMAILGDTLGKIAYEKAGIIKEKV 192
Query: 201 PLVL 204
PLV+
Sbjct: 193 PLVM 196
Database: uniref100
Posted date: Jan 5, 2005 1:24 AM
Number of letters in database: 848,049,833
Number of sequences in database: 2,790,947
Lambda K H
0.327 0.140 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 778,181,256
Number of Sequences: 2790947
Number of extensions: 31128976
Number of successful extensions: 104074
Number of sequences better than 10.0: 615
Number of HSP's better than 10.0 without gapping: 392
Number of HSP's successfully gapped in prelim test: 223
Number of HSP's that attempted gapping in prelim test: 102546
Number of HSP's gapped (non-prelim): 836
length of query: 516
length of database: 848,049,833
effective HSP length: 132
effective length of query: 384
effective length of database: 479,644,829
effective search space: 184183614336
effective search space used: 184183614336
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 77 (34.3 bits)
Medicago: description of AC124963.22