BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC149135.13 - phase: 0
(316 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
RRM1_HUMAN (Q9UET6) Putative ribosomal RNA methyltransferase 1 (... 357 2e-98
YEK3_SCHPO (O36015) Putative ribosomal RNA methyltransferase C4F... 324 2e-88
RRM2_CAEEL (Q22031) Putative ribosomal RNA methyltransferase R74... 319 5e-87
YBR1_YEAST (P38238) Putative ribosomal RNA methyltransferase YBR... 292 7e-79
RRM1_DROME (Q9VEP1) Putative ribosomal RNA methyltransferase CG5... 279 6e-75
RRM2_DROME (Q9VDD9) Putative ribosomal RNA methyltransferase CG7... 267 3e-71
PMT2_SCHPO (O42832) Probable rRNA methyltransferase pmt2 (EC 2.1... 144 3e-34
SPB1_YEAST (P25582) Putative rRNA methyltransferase SPB1 (EC 2.1... 144 4e-34
YK51_ARCFU (O28228) Putative ribosomal RNA methyltransferase (EC... 120 4e-27
YD76_METJA (Q58771) Putative ribosomal RNA methyltransferase (EC... 120 6e-27
RRMJ_BUCAI (P57463) Ribosomal RNA large subunit methyltransferas... 116 6e-26
YH73_METTH (O27801) Putative ribosomal RNA methyltransferase (EC... 116 8e-26
RRM2_HUMAN (Q9UI43) Putative ribosomal RNA methyltransferase 2 (... 113 5e-25
RRMJ_RICPR (Q9ZE00) Ribosomal RNA large subunit methyltransferas... 112 2e-24
RRMJ_BUCAP (Q8K9G7) Ribosomal RNA large subunit methyltransferas... 108 2e-23
RRMJ_PSEAE (P95454) Ribosomal RNA large subunit methyltransferas... 99 1e-20
YBOF_SCHPO (P78860) Putative ribosomal RNA methyltransferase C2G... 98 2e-20
RRMJ_ECOLI (P28692) Ribosomal RNA large subunit methyltransferas... 98 2e-20
RRMJ_HAEIN (P45162) Ribosomal RNA large subunit methyltransferas... 92 2e-18
Y682_TREPA (O83687) Putative ribosomal RNA methyltransferase (EC... 87 7e-17
>RRM1_HUMAN (Q9UET6) Putative ribosomal RNA methyltransferase 1 (EC
2.1.1.-) (rRNA (uridine-2'-O-)-methyltransferase) (JM23
protein)
Length = 329
Score = 357 bits (917), Expect = 2e-98
Identities = 176/300 (58%), Positives = 218/300 (72%), Gaps = 18/300 (6%)
Query: 1 MGKASRDKRDIYYRKAKEEGWRARSAFKLLQIDEEFNIFEGVKRVVDLCAAPGSWSQVLS 60
MG+ S+DKRD+YYR AKE GWRARSAFKLLQ+D+EF +F+GV R VDLCAAPGSWSQVLS
Sbjct: 1 MGRTSKDKRDVYYRLAKENGWRARSAFKLLQLDKEFQLFQGVTRAVDLCAAPGSWSQVLS 60
Query: 61 RKLYLPAKLAPDAKDENLPLIVAIDLQPMAPIEGVIQVQGDITNARTAEVVIRHFDGCKA 120
+K+ + +VA+DLQ MAP+ GV+Q+QGDIT TA+ +I+HF GC A
Sbjct: 61 QKI----------GGQGSGHVVAVDLQAMAPLPGVVQIQGDITQLSTAKEIIQHFKGCPA 110
Query: 121 NLVVCDGAPDVTGLHDMDEFVQSQLILAGLTIVTHVLKEGGKFIAKIFRGKDTSLLYCQL 180
+LVVCDGAPDVTGLHD+DE++Q+QL+LA L I THVLK GG F+AKIFRG+D +LLY QL
Sbjct: 111 DLVVCDGAPDVTGLHDVDEYMQAQLLLAALNIATHVLKPGGCFVAKIFRGRDVTLLYSQL 170
Query: 181 KLFFPVVTFAKPKSSRNSSIEAFAVCENYSPPEGFNPKDLHRLLEKVGSPSGVDDTDCVS 240
++FF V AKP+SSRNSSIEAFAVC+ Y PPEGF P LL+ P
Sbjct: 171 QVFFSSVLCAKPRSSRNSSIEAFAVCQGYDPPEGFIPDLSKPLLDHSYDPD--------F 222
Query: 241 GWLEGPNKVYIPFLACGDLTGYDSDRSYPLPKVAGGTYQSLDPVQPPIAPPYKRALELKK 300
L+GP ++ +PF+ CGDL+ YDSDRSYPL G Y+ P QPPI+PPY+ A LK+
Sbjct: 223 NQLDGPTRIIVPFVTCGDLSSYDSDRSYPLDLEGGSEYKYTPPTQPPISPPYQEACTLKR 282
>YEK3_SCHPO (O36015) Putative ribosomal RNA methyltransferase
C4F10.03c (EC 2.1.1.-) (rRNA
(uridine-2'-O-)-methyltransferase)
Length = 285
Score = 324 bits (831), Expect = 2e-88
Identities = 170/301 (56%), Positives = 216/301 (71%), Gaps = 24/301 (7%)
Query: 1 MGKASRDKRDIYYRKAKEEGWRARSAFKLLQIDEEFNIFEGVKRVVDLCAAPGSWSQVLS 60
MG++S+DKRD YYR AKE+GWRARSAFKLLQ++E+FN+FEG KRVVDLCAAPGSWSQVLS
Sbjct: 1 MGRSSKDKRDAYYRLAKEQGWRARSAFKLLQLNEQFNLFEGAKRVVDLCAAPGSWSQVLS 60
Query: 61 RKLY--LPAKLAPDAKDENLPLIVAIDLQPMAPIEGVIQVQGDITNARTAEVVIRHFDGC 118
R+L + +A D K P+IVA+DLQPMAPI+GV +Q DIT+ T +++ HF
Sbjct: 61 RELLKNIDTSIAADEK----PMIVAVDLQPMAPIDGVCTLQLDITHPNTLSIILSHFGNE 116
Query: 119 KANLVVCDGAPDVTGLHDMDEFVQSQLILAGLTIVTHVLKEGGKFIAKIFRGKDTSLLYC 178
A+LVV DGAPDVTGLHD+DE++Q+Q++LA + VLK GGKF+AKIFRG+D SLLY
Sbjct: 117 PADLVVSDGAPDVTGLHDLDEYIQAQILLAAFNLAVCVLKPGGKFVAKIFRGRDVSLLYS 176
Query: 179 QLKLFFPVVTFAKPKSSRNSSIEAFAVCENYSPPEGFNPKDLHRLLEKVGSPSGVDDTDC 238
QL+L F V+ AKP+SSR SSIE+F VCE+++PP F P DL + L +D T+
Sbjct: 177 QLRLMFRKVSCAKPRSSRASSIESFVVCEDFNPPSNFQP-DLTKPL------CVIDPTNA 229
Query: 239 VSGWLEGPNKVYIPFLACGDLTGYDSDRSYPLPKVAGGTYQSLDPVQPPIAPPYKRALEL 298
PF+ACGDL GYD+D +YP+ +LD +QPP APPYKRA+EL
Sbjct: 230 ---------HEIAPFIACGDLDGYDADATYPVE--INMKKATLDVIQPPTAPPYKRAIEL 278
Query: 299 K 299
K
Sbjct: 279 K 279
>RRM2_CAEEL (Q22031) Putative ribosomal RNA methyltransferase R74.7
(EC 2.1.1.-) (rRNA (uridine-2'-O-)-methyltransferase)
Length = 337
Score = 319 bits (818), Expect = 5e-87
Identities = 171/312 (54%), Positives = 214/312 (67%), Gaps = 33/312 (10%)
Query: 1 MGKASRDKRDIYYRKAKEEGWRARSAFKLLQIDEEFNIFEGVKRVVDLCAAPGSWSQVLS 60
MGK SRDKRDIYYR AKE WRARSAFKL+QID+EF I +GV+R VDLCAAPGSWSQVLS
Sbjct: 1 MGKTSRDKRDIYYRLAKENKWRARSAFKLMQIDDEFQILKGVRRAVDLCAAPGSWSQVLS 60
Query: 61 RKLYLPAKLAPDAKDENLPLIVAIDLQPMAPIEGVIQVQGDITNARTAEVVIRHFDGCKA 120
++LY +++ IVAIDLQPMAPI GVIQ+QGDIT+ TA VI+HF G K+
Sbjct: 61 KRLY---------EEDQEAKIVAIDLQPMAPIPGVIQLQGDITSVDTANQVIKHFSGEKS 111
Query: 121 NLVVCDGAPDVTGLHDMDEFVQSQLILAGLTIVTHVLKEGGKFIAKIFRGKDTSLLYCQL 180
++V+CDGAPDVTG+H +DEF+Q++LILA I +HVLKEGG F+AKIFR +++SLLY Q+
Sbjct: 112 DIVICDGAPDVTGIHSLDEFMQAELILAAFNITSHVLKEGGNFLAKIFRSRNSSLLYAQM 171
Query: 181 KLFFPVVTFAKPKSSRNSSIEAFAVCENYSPPEGFNPKDLHRLLEKVGSPSGVDDTDCVS 240
K +F V AKP+SSR SS EAF +C +YSPPEGF P L+ + + D +
Sbjct: 172 KKYFKKVYLAKPRSSRQSSCEAFVLCLDYSPPEGFVPTMGKTSLD--ATDASAISPDIID 229
Query: 241 GWLEGPNKVYIPFLACGDLTGYDSDRSYPL------PK-----VAGGTYQSLDPVQPPIA 289
G F+ CGDL+G+DS++SYPL PK Y+ D VQPP
Sbjct: 230 G-----------FVTCGDLSGWDSEKSYPLDIDACFPKGEIDEEQKKRYEFKDVVQPPTD 278
Query: 290 PPYKRALELKKA 301
P YK AL+ KK+
Sbjct: 279 PAYKAALDKKKS 290
>YBR1_YEAST (P38238) Putative ribosomal RNA methyltransferase
YBR061c (EC 2.1.1.-) (rRNA
(uridine-2'-O-)-methyltransferase)
Length = 310
Score = 292 bits (748), Expect = 7e-79
Identities = 156/308 (50%), Positives = 214/308 (68%), Gaps = 12/308 (3%)
Query: 1 MGKASRDKRDIYYRKAKEEGWRARSAFKLLQIDEEFNIFE--GVKRVVDLCAAPGSWSQV 58
MGK+S+DKRD+YYRKAKE+G+RARSAFKLLQ++++F+ + +KRVVDLCAAPGSWSQV
Sbjct: 1 MGKSSKDKRDLYYRKAKEQGYRARSAFKLLQLNDQFHFLDDPNLKRVVDLCAAPGSWSQV 60
Query: 59 LSRKLYLPAKLAPDAKDENLPLIVAIDLQPMAPIEGVIQVQGDITNARTAEVVIRHFDGC 118
LSRKL+ + + D +D IV++DLQPM+PI V +Q DIT+ +T +++ F
Sbjct: 61 LSRKLFDESP-SSDKEDRK---IVSVDLQPMSPIPHVTTLQADITHPKTLARILKLFGNE 116
Query: 119 KANLVVCDGAPDVTGLHDMDEFVQSQLILAGLTIVTHVLKEGGKFIAKIFRGKDTSLLYC 178
KA+ V DGAPDVTGLHD+DE+VQ QLI++ L + +LK+GG F+AKIFRG+D +LY
Sbjct: 117 KADFVCSDGAPDVTGLHDLDEYVQQQLIMSALQLTACILKKGGTFVAKIFRGRDIDMLYS 176
Query: 179 QLKLFFPVVTFAKPKSSRNSSIEAFAVCENYSPPEGFNPK-DLHRLLEKVGSPSGVDD-- 235
QL F + AKP+SSR +S+EAF VC Y+PP + PK D++ +++ ++
Sbjct: 177 QLGYLFDKIVCAKPRSSRGTSLEAFIVCLGYNPPSNWTPKLDVNTSVDEFFQGCFLNKLC 236
Query: 236 -TDCVSGWLEGPNKVYIPFLACGDLTGYDSDRSY-PLPKVAGGTYQSLDPVQPPIAPPYK 293
+D +S W E + F+ACG L +DSD +Y LP GT SLDPVQ P PPYK
Sbjct: 237 ISDKLSHWNEEERNI-AEFMACGSLQSFDSDATYHDLPSSVAGTSSSLDPVQSPTNPPYK 295
Query: 294 RALELKKA 301
+ALELK++
Sbjct: 296 KALELKRS 303
>RRM1_DROME (Q9VEP1) Putative ribosomal RNA methyltransferase CG5220
(EC 2.1.1.-) (rRNA (uridine-2'-O-)-methyltransferase)
Length = 302
Score = 279 bits (714), Expect = 6e-75
Identities = 158/321 (49%), Positives = 203/321 (63%), Gaps = 29/321 (9%)
Query: 1 MGKASRDKRDIYYRKAKEEGWRARSAFKLLQIDEEFNIFEGVKRVVDLCAAPGSWSQVLS 60
MGK S+DKRDIYYR+AK+EGWRARSAFKLL +DE + I GV+R VDLCAAPGSWSQVLS
Sbjct: 1 MGKTSKDKRDIYYRQAKDEGWRARSAFKLLHVDEAYGILNGVQRAVDLCAAPGSWSQVLS 60
Query: 61 RKLYLPAKLAPDAKDENLPL-IVAIDLQPMAPIEGVIQVQGDITNARTAEVVIRHFDGC- 118
RKLY + DE + I+A+DLQ MAPI G++Q+QGDIT TAE +I HF G
Sbjct: 61 RKLYDTC----ETDDEKSAVKIIAVDLQAMAPIRGILQLQGDITKQSTAEAIIGHFGGNE 116
Query: 119 KANLVVCDGAPDVTGLHDMDEFVQSQLILAGLTIVTHVLKEGGKFIAKIFRGKDTSLLYC 178
KA LVVCDGAPDVTG+H+MDE++Q QL++A L+I T VL+ GG F+AKIF+G TSLL
Sbjct: 117 KAQLVVCDGAPDVTGVHEMDEYMQHQLLVAALSIATCVLETGGTFVAKIFKGNATSLLSS 176
Query: 179 QLKLFFPVVTFAKPKSSRNSSIEAFAVCENYSPPEGFNPK-------DLHRLLEKVGSPS 231
Q+++FF KP SSR SSIEAF VC ++ PEG+ P+ D+ L +K GS
Sbjct: 177 QMQIFFKKFDIYKPPSSRPSSIEAFVVCSDFCLPEGYIPQVINPARDDIRLLAQKTGSE- 235
Query: 232 GVDDTDCVSGWLEGPNKVYIPFLACGDLTGYDSDRSYPLPKVAGGTYQSLDPVQPPIAPP 291
N+ +PF+ACGDL G SD + + +L+ V +
Sbjct: 236 --------------VNRRLVPFIACGDLNGL-SDPEEGKTSSSDESKSNLEYVYDAVMDD 280
Query: 292 YKRALELKKASPQGFRELENL 312
LE K+ Q + E ++
Sbjct: 281 ASYPLEFKEILKQVYDEQRHI 301
>RRM2_DROME (Q9VDD9) Putative ribosomal RNA methyltransferase CG7009
(EC 2.1.1.-) (rRNA (uridine-2'-O-)-methyltransferase)
Length = 320
Score = 267 bits (682), Expect = 3e-71
Identities = 150/302 (49%), Positives = 196/302 (64%), Gaps = 27/302 (8%)
Query: 1 MGKASRDKRDIYYRKAKEEGWRARSAFKLLQIDEEFNIFEGVKRVVDLCAAPGSWSQVLS 60
MG+ S+DKRDI+YR AKE+GWRARSAFKLLQ DE F + EG+ R VDLCAAPGSWSQVL+
Sbjct: 1 MGRTSKDKRDIFYRLAKEQGWRARSAFKLLQADETFQLLEGLTRAVDLCAAPGSWSQVLA 60
Query: 61 RKLYLPAKLAPDAKDENLPLIVAIDLQPMAPIEGVIQVQGDITNARTAEVVIRHFDGCKA 120
++LY P L P+ +++ I+A+DLQ MAPIEGV Q++ DI+ TAE +I F G KA
Sbjct: 61 KRLYEP--LPPEEREK--VKIIAVDLQGMAPIEGVKQLRADISKESTAEAIIEFFGGEKA 116
Query: 121 NLVVCDGAPDVTGLHDMDEFVQSQLILAGLTIVTHVLKEGGKFIAKIFRGKDTSLLYCQL 180
+VV DGAPD TG+HD D +VQ +L+L+ L+I T +L+EGG F++KI+R TS LY QL
Sbjct: 117 QIVVSDGAPDSTGMHDFDSYVQGELLLSALSISTFILEEGGSFVSKIYRADRTSRLYTQL 176
Query: 181 KLFFPVVTFAKPKSSRNSSIEAFAVCENYSPPEGFNPKDLHRLLEKVGSPSGVDDTDCVS 240
K FF V KP +SRNSSIEAF V + P+G+ P +L + D
Sbjct: 177 KRFFKNVCVFKPSASRNSSIEAFVVAREFCLPDGYKPCNL-----------TTEWHDQPE 225
Query: 241 GWL----EGPNKVYIPFLAC-GDLTGYDSDRSYPLPKVAGGTYQSLDPVQPPIAPPYKRA 295
W+ E P V +PF+A G+L DSDR+Y L G Y +PVQ P+ Y+
Sbjct: 226 SWVGRKKESPPVVQVPFVAYKGEL---DSDRTYDL----GENYVYKEPVQQPLTAAYQDI 278
Query: 296 LE 297
L+
Sbjct: 279 LQ 280
>PMT2_SCHPO (O42832) Probable rRNA methyltransferase pmt2 (EC
2.1.1.-)
Length = 802
Score = 144 bits (363), Expect = 3e-34
Identities = 98/287 (34%), Positives = 146/287 (50%), Gaps = 28/287 (9%)
Query: 3 KASRDKRDIYYRKAKEEGWRARSAFKLLQIDEEFNIFEGVKRVVDLCAAPGSWSQVLSRK 62
K ++ + D +Y+ AKE+G+R+R+AFKL+Q++++++ E K ++DLCAAPG W QV S K
Sbjct: 7 KTAKGRLDKWYKLAKEQGYRSRAAFKLVQLNQKYSFLEKAKVIIDLCAAPGGWLQVAS-K 65
Query: 63 LYLPAKLAPDAKDENLPLIVAIDLQPMAPIEGVIQVQGDITNARTAEVVIRHFDGCKANL 122
P L IV +DL P+ PI DIT+ + + + KA++
Sbjct: 66 TCKPGSL-----------IVGVDLAPIKPIPNCHTFVEDITSDKCRSQLRGYLKTWKADV 114
Query: 123 VVCDGAPDVTGLHDMDEFVQSQLILAGLTIVTHVLKEGGKFIAKIFRGKDTSLLYCQLKL 182
V+ DGAP+V D + Q+QL+L + + L GG F+ K+FR +D + L K
Sbjct: 115 VLHDGAPNVGSAWLQDAYGQAQLVLMSMKLACEFLVAGGTFVTKVFRSRDYNNLLWVFKQ 174
Query: 183 FFPVVTFAKPKSSRNSSIEAFAVCENYSPPEGFNPK--DLHRLLEKVGSPSGVDDTDCVS 240
F V KP SSRN S E F VC Y P+ +P+ D + E+V P V + D
Sbjct: 175 LFNKVEATKPPSSRNVSAEIFVVCRGYKAPKKLDPRFTDPRTVFEEVQEP--VTNVDA-- 230
Query: 241 GWLEGPNKVYIPFLACGDLTGYDSDRSYPLPK--VAGGTYQSLDPVQ 285
KV+ P GY +D Y L K +A + DP+Q
Sbjct: 231 -------KVFHPEKRKRSREGY-ADDDYTLHKTVLASEFVTANDPIQ 269
>SPB1_YEAST (P25582) Putative rRNA methyltransferase SPB1 (EC
2.1.1.-)
Length = 841
Score = 144 bits (362), Expect = 4e-34
Identities = 89/217 (41%), Positives = 119/217 (54%), Gaps = 13/217 (5%)
Query: 3 KASRDKRDIYYRKAKEEGWRARSAFKLLQIDEEFNIF-EGVKRVVDLCAAPGSWSQVLSR 61
K S+ + D YY AKE+G+RARS+FK++QI+E++ F E K V+DLCAAPGSW QV S
Sbjct: 7 KNSKGRLDRYYYLAKEKGYRARSSFKIIQINEKYGHFLEKSKVVIDLCAAPGSWCQVAS- 65
Query: 62 KLYLPAKLAPDAKDENLPLIVAIDLQPMAPIEGVIQVQGDITNARTAEVVIRHFDGCKAN 121
KL P LI+ +D+ PM P+ VI Q DIT + + KA+
Sbjct: 66 ------KLCPVNS-----LIIGVDIVPMKPMPNVITFQSDITTEDCRSKLRGYMKTWKAD 114
Query: 122 LVVCDGAPDVTGLHDMDEFVQSQLILAGLTIVTHVLKEGGKFIAKIFRGKDTSLLYCQLK 181
V+ DGAP+V D F QSQL L L + L G F+ KIFR KD + L +
Sbjct: 115 TVLHDGAPNVGLGWVQDAFTQSQLTLQALKLAVENLVVNGTFVTKIFRSKDYNKLIWVFQ 174
Query: 182 LFFPVVTFAKPKSSRNSSIEAFAVCENYSPPEGFNPK 218
F V KP +SRN S E F VC+ + P+ +P+
Sbjct: 175 QLFEKVEATKPPASRNVSAEIFVVCKGFKAPKRLDPR 211
>YK51_ARCFU (O28228) Putative ribosomal RNA methyltransferase (EC
2.1.1.-) (rRNA (uridine-2'-O-)-methyltransferase)
Length = 191
Score = 120 bits (301), Expect = 4e-27
Identities = 71/204 (34%), Positives = 112/204 (54%), Gaps = 17/204 (8%)
Query: 6 RDKRDIYYRKAKEEGWRARSAFKLLQIDEEFNIFEGVKRVVDLCAAPGSWSQVLSRKLYL 65
+D++D YY KAK+EG+R+R+A+KLLQ++ F + V+DL A PG WSQV + L
Sbjct: 2 KDRQDYYYWKAKKEGYRSRAAYKLLQMNRTFKLIREGDLVLDLGATPGGWSQVAA---LL 58
Query: 66 PAKLAPDAKDENLPLIVAIDLQPMAPIEGVIQVQGDITNARTAEVVIRHFDGCKANLVVC 125
A+ +VA+D+ PM P+E V ++GDIT T E IR ++V+
Sbjct: 59 GAR------------VVAVDINPMKPLENVTFIRGDITLPETLE-KIREISP-DYDVVMS 104
Query: 126 DGAPDVTGLHDMDEFVQSQLILAGLTIVTHVLKEGGKFIAKIFRGKDTSLLYCQLKLFFP 185
D +P ++G +D L A +I VLK GG F+ K+F+G++ + +LK F
Sbjct: 105 DASPKISGKWTIDHLRSIDLARASFSIAKEVLKPGGNFVVKVFQGEEIQKFFNELKPHFR 164
Query: 186 VVTFAKPKSSRNSSIEAFAVCENY 209
F P++SR S E + + + +
Sbjct: 165 FKKFHSPQASRKRSAEVYFIGKRF 188
>YD76_METJA (Q58771) Putative ribosomal RNA methyltransferase (EC
2.1.1.-) (rRNA (uridine-2'-O-)-methyltransferase)
Length = 245
Score = 120 bits (300), Expect = 6e-27
Identities = 71/208 (34%), Positives = 116/208 (55%), Gaps = 18/208 (8%)
Query: 8 KRDIYYRKAKEEGWRARSAFKLLQIDEEFNIFEGVKRVVDLCAAPGSWSQVLSRKLYLPA 67
KRD YY+ AK+ +R+R++FKL+Q++E+FN+ + K V+DL APG W QV +R++
Sbjct: 13 KRDFYYKLAKKLKYRSRASFKLMQLNEKFNVIKPGKIVLDLGCAPGGWMQV-AREIV--- 68
Query: 68 KLAPDAKDENLPLIVAIDLQPMAPIE--GVIQVQGDIT---NARTAEVVIRHFDGCKANL 122
+ ++ IDLQP+ P E V+ ++GD T N +I + D K ++
Sbjct: 69 --------GDKGFVIGIDLQPVKPFEYDNVVAIKGDFTLEENLNKIRELIPN-DEKKVDV 119
Query: 123 VVCDGAPDVTGLHDMDEFVQSQLILAGLTIVTHVLKEGGKFIAKIFRGKDTSLLYCQLKL 182
V+ D +P+++G D+D L+ L I T +LKE G F+AK+F G +K
Sbjct: 120 VISDASPNISGYWDIDHARSIDLVTTALQIATEMLKERGNFVAKVFYGDMIDDYVNLVKK 179
Query: 183 FFPVVTFAKPKSSRNSSIEAFAVCENYS 210
+F V KP++SR S E + + + Y+
Sbjct: 180 YFEKVYITKPQASRKESAEVYVIAKRYT 207
>RRMJ_BUCAI (P57463) Ribosomal RNA large subunit methyltransferase J
(EC 2.1.1.-) (rRNA (uridine-2'-O-)-methyltransferase)
(23S rRNA m2U2552 methyltransferase)
Length = 206
Score = 116 bits (291), Expect = 6e-26
Identities = 70/195 (35%), Positives = 105/195 (52%), Gaps = 12/195 (6%)
Query: 9 RDIYYRKAKEEGWRARSAFKLLQIDEEFNIFEGVKRVVDLCAAPGSWSQVLSRKLYLPAK 68
+D Y + AK+ R+R+ FKL Q+D+ IF+ V+DL AAPGSWSQ S ++ +
Sbjct: 19 QDQYVKAAKKNNIRSRAWFKLEQLDKNNKIFKIGMNVIDLGAAPGSWSQYASNRIGKKGR 78
Query: 69 LAPDAKDENLPLIVAIDLQPMAPIEGVIQVQGDITNARTAEVVIRHFDGCKANLVVCDGA 128
I+A D+ P+ PI GV QGD N +T +++ F +LV+ D A
Sbjct: 79 ------------IIACDILPIRPITGVDIFQGDFRNKKTLNLMLNTFSNITFHLVMSDMA 126
Query: 129 PDVTGLHDMDEFVQSQLILAGLTIVTHVLKEGGKFIAKIFRGKDTSLLYCQLKLFFPVVT 188
P++TG +D +L L I HVL + G F+ K F+G+ + LY ++K+ F +
Sbjct: 127 PNITGNFSIDMPRIIELCKLALKISEHVLSKNGIFLLKSFQGEGFNELYKEIKMLFKKIK 186
Query: 189 FAKPKSSRNSSIEAF 203
KPK+SR S E F
Sbjct: 187 ICKPKTSRTRSREIF 201
>YH73_METTH (O27801) Putative ribosomal RNA methyltransferase (EC
2.1.1.-) (rRNA (uridine-2'-O-)-methyltransferase)
Length = 211
Score = 116 bits (290), Expect = 8e-26
Identities = 75/217 (34%), Positives = 117/217 (53%), Gaps = 17/217 (7%)
Query: 1 MGKA--SRDKRDIYYRKAKEEGWRARSAFKLLQIDEEFNIFEGVKRVVDLCAAPGSWSQV 58
MGK + KRD YYR AK+E +R+R+++KLLQ++ ++ + + RV+DL AAPG WSQV
Sbjct: 1 MGKRWQAERKRDHYYRSAKKENYRSRASYKLLQLNNKYKLIKKGDRVLDLGAAPGGWSQV 60
Query: 59 LSRKLYLPAKLAPDAKDENLPLIVAIDLQPMA--PIEGVIQVQGDITNARTAEVVIRHFD 116
A D E L+VA+DLQ + P E ++GD T+ + +IR
Sbjct: 61 -----------ALDKVGEE-GLVVAVDLQRIKGFPAENFRAIRGDFTDPEVKDKIIRELG 108
Query: 117 GCKANLVVCDGAPDVTGLHDMDEFVQSQLILAGLTIVTHVLKEGGKFIAKIFRGKDTSLL 176
G +A++V+ D AP ++G+ D+D L+ L I VL G + K F+G + +
Sbjct: 109 G-RADVVISDAAPSLSGIRDIDHLRSVDLVENVLDIAYRVLDRKGNILIKAFQGPELDRV 167
Query: 177 YCQLKLFFPVVTFAKPKSSRNSSIEAFAVCENYSPPE 213
+L+ F + KP SSR +S E + V ++ E
Sbjct: 168 IKELRKDFWKLKTTKPASSRKASAEMYIVGRDFKGKE 204
>RRM2_HUMAN (Q9UI43) Putative ribosomal RNA methyltransferase 2 (EC
2.1.1.-) (rRNA (uridine-2'-O-)-methyltransferase)
Length = 246
Score = 113 bits (283), Expect = 5e-25
Identities = 68/211 (32%), Positives = 112/211 (52%), Gaps = 5/211 (2%)
Query: 5 SRDKRDIYYRKAKEEGWRARSAFKLLQIDEEFNIFEGVKRVVDLCAAPGSWSQVLSRKLY 64
+R RD + + AK E +R RSAFKLL+++E I RV+D AAPG+WSQV +K+
Sbjct: 36 TRHLRDPFVKAAKVESYRCRSAFKLLEVNERHQILRPGLRVLDCGAAPGAWSQVAVQKV- 94
Query: 65 LPAKLAPDAKDENLPLIVAIDLQPMAPIEGVIQV-QGDITNARTAEVVIRHFDGCKANLV 123
A + ++ +DL + P+EG + D+T+ RT++ ++ G +A+++
Sbjct: 95 ---NAAGTDPSSPVGFVLGVDLLHIFPLEGATFLCPADVTDPRTSQRILEVLPGRRADVI 151
Query: 124 VCDGAPDVTGLHDMDEFVQSQLILAGLTIVTHVLKEGGKFIAKIFRGKDTSLLYCQLKLF 183
+ D AP+ TG D+D L L L++ +L+ GG F+ K + G + L +L
Sbjct: 152 LSDMAPNATGFRDLDHDRLISLCLTLLSVTPDILQPGGTFLCKTWAGSQSRRLQRRLTEE 211
Query: 184 FPVVTFAKPKSSRNSSIEAFAVCENYSPPEG 214
F V KP++SR S E + + Y +G
Sbjct: 212 FQNVRIIKPEASRKESSEVYFLATQYHGRKG 242
>RRMJ_RICPR (Q9ZE00) Ribosomal RNA large subunit methyltransferase J
(EC 2.1.1.-) (rRNA (uridine-2'-O-)-methyltransferase)
(23S rRNA m2U2552 methyltransferase) (Cell division
protein ftsJ homolog)
Length = 227
Score = 112 bits (279), Expect = 2e-24
Identities = 78/204 (38%), Positives = 107/204 (52%), Gaps = 10/204 (4%)
Query: 6 RDKRDIYYRKAKEEGWRARSAFKLLQIDEEFNIFEGVKRVVDLCAAPGSWSQVLSRKLYL 65
R D Y KA+ EG+R+R+A+KLL+I +F +F ++VDL AAPG WSQV S+ +
Sbjct: 31 RQLNDPYVAKARLEGFRSRAAYKLLEIHYKFRLFTPNMKIVDLGAAPGGWSQVASKLI-- 88
Query: 66 PAKLAPDAKDENL-PLIVAIDLQPMAPIEGVIQVQGDITNARTAEVVIRHFDGCKANLVV 124
A D NL I++IDL + PI GV +Q D T E++I + +G KA++V+
Sbjct: 89 ------KASDNNLNNKIISIDLLEIEPIVGVEFLQKDFFEKDTEELIIHNLEG-KADIVM 141
Query: 125 CDGAPDVTGLHDMDEFVQSQLILAGLTIVTHVLKEGGKFIAKIFRGKDTSLLYCQLKLFF 184
D A + G D L VLK FIAKIFRG + L ++K F
Sbjct: 142 SDMASNTIGHKATDHMRTLLLCEQAFEFALKVLKPSCHFIAKIFRGGAETALLNKVKREF 201
Query: 185 PVVTFAKPKSSRNSSIEAFAVCEN 208
V KP SSR+ S E + V N
Sbjct: 202 RTVKHFKPVSSRSESTEIYLVALN 225
>RRMJ_BUCAP (Q8K9G7) Ribosomal RNA large subunit methyltransferase J
(EC 2.1.1.-) (rRNA (uridine-2'-O-)-methyltransferase)
(23S rRNA m2U2552 methyltransferase)
Length = 206
Score = 108 bits (270), Expect = 2e-23
Identities = 63/195 (32%), Positives = 103/195 (52%), Gaps = 12/195 (6%)
Query: 9 RDIYYRKAKEEGWRARSAFKLLQIDEEFNIFEGVKRVVDLCAAPGSWSQVLSRKLYLPAK 68
+D Y ++AK++ R+RS FKL +ID+ +F+ V+DL ++PG WSQ ++K+
Sbjct: 19 QDQYVKEAKKQKIRSRSWFKLEEIDKNNRLFKPGMNVLDLGSSPGGWSQYAAKKI----- 73
Query: 69 LAPDAKDENLPLIVAIDLQPMAPIEGVIQVQGDITNARTAEVVIRHFDGCKANLVVCDGA 128
I+A D+ PM I+GV QGD N +T +++ + NL++ D A
Sbjct: 74 -------GKKGYILACDILPMKKIKGVDFFQGDFCNKKTLNLILTNLSNVNLNLIMSDMA 126
Query: 129 PDVTGLHDMDEFVQSQLILAGLTIVTHVLKEGGKFIAKIFRGKDTSLLYCQLKLFFPVVT 188
P++TG +D ++ TI HVL G + K F+G+ + + Q+K F +
Sbjct: 127 PNITGCSSIDMPRIIEICKTVFTISDHVLSRNGVVLVKSFQGEGFNEFFAQMKNLFSKIK 186
Query: 189 FAKPKSSRNSSIEAF 203
KPK+SR+ S E F
Sbjct: 187 ICKPKTSRSRSREIF 201
>RRMJ_PSEAE (P95454) Ribosomal RNA large subunit methyltransferase J
(EC 2.1.1.-) (rRNA (uridine-2'-O-)-methyltransferase)
(23S rRNA m2U2552 methyltransferase) (Cell division
protein ftsJ homolog)
Length = 207
Score = 99.4 bits (246), Expect = 1e-20
Identities = 64/200 (32%), Positives = 99/200 (49%), Gaps = 12/200 (6%)
Query: 10 DIYYRKAKEEGWRARSAFKLLQIDEEFNIFEGVKRVVDLCAAPGSWSQVLSRKLYLPAKL 69
D Y + A+ +G+R+R+++KLL+I E+ I VVDL AAPG WSQV SR + +L
Sbjct: 17 DPYVKMAQRDGYRSRASYKLLEIQEKDRILRPGMTVVDLGAAPGGWSQVTSRVIGDRGRL 76
Query: 70 APDAKDENLPLIVAIDLQPMAPIEGVIQVQGDITNARTAEVVIRHFDGCKANLVVCDGAP 129
+A D+ M I V +QGD T ++ +LV+ D AP
Sbjct: 77 ------------IASDILEMDSIPDVTFIQGDFTEDAVFARILEAIGDHPVDLVISDMAP 124
Query: 130 DVTGLHDMDEFVQSQLILAGLTIVTHVLKEGGKFIAKIFRGKDTSLLYCQLKLFFPVVTF 189
+++G+ D+ L L + VL+ GG F+ KIF+G+ + Q + F V
Sbjct: 125 NMSGVRAADQPRAMYLCELALDLAGRVLRPGGDFLIKIFQGEGFDQYHKQAREMFDKVQM 184
Query: 190 AKPKSSRNSSIEAFAVCENY 209
KP SSR+ S E + + +
Sbjct: 185 RKPLSSRDRSREQYLLARGF 204
>YBOF_SCHPO (P78860) Putative ribosomal RNA methyltransferase
C2G2.15c (EC 2.1.1.-) (rRNA
(uridine-2'-O-)-methyltransferase)
Length = 218
Score = 98.2 bits (243), Expect = 2e-20
Identities = 63/220 (28%), Positives = 103/220 (46%), Gaps = 24/220 (10%)
Query: 4 ASRDKRDIYYRKAKEEGWRARSAFKLLQIDEEFNIFEGVKRVVDLCAAPGSWSQVLSRKL 63
A++ +D Y +K+K + +R+R+A+KL++++ ++ V+D+ APGSWSQV + +
Sbjct: 11 AAKRSKDFYRKKSKIDNFRSRAAYKLIELNSKYRFINKEDVVIDVGFAPGSWSQVAKKLV 70
Query: 64 YLPAKLAPDAKDENLPLIVAIDLQPMAPIEGVIQVQGDITNARTAEVVIR---------- 113
N ++ ID+Q +AP EGV+ + GDI + T +
Sbjct: 71 ------------GNKGKVIGIDIQHIAPPEGVLPIYGDIRDPNTLTKLFEALRLLHEPNT 118
Query: 114 --HFDGCKANLVVCDGAPDVTGLHDMDEFVQSQLILAGLTIVTHVLKEGGKFIAKIFRGK 171
D + V+ D TG+ D + +L + L + LK G FI K + G
Sbjct: 119 NDSIDCRVVDAVISDMLHKATGIRIRDHALSMELCASALHVALTFLKSNGSFICKFYMGD 178
Query: 172 DTSLLYCQLKLFFPVVTFAKPKSSRNSSIEAFAVCENYSP 211
+ + L LK F V KPK+S S EA+ VC P
Sbjct: 179 EDADLQNLLKSHFRFVQVMKPKASLKESREAYFVCLERKP 218
>RRMJ_ECOLI (P28692) Ribosomal RNA large subunit methyltransferase J
(EC 2.1.1.-) (rRNA (uridine-2'-O-)-methyltransferase)
(23S rRNA m2U2552 methyltransferase) (Cell division
protein ftsJ)
Length = 209
Score = 98.2 bits (243), Expect = 2e-20
Identities = 64/202 (31%), Positives = 101/202 (49%), Gaps = 12/202 (5%)
Query: 10 DIYYRKAKEEGWRARSAFKLLQIDEEFNIFEGVKRVVDLCAAPGSWSQVLSRKLYLPAKL 69
D Y ++A+++G R+R+ FKL +I + +F+ VVDL AAPG WSQ Y+ ++
Sbjct: 20 DKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGAAPGGWSQ------YVVTQI 73
Query: 70 APDAKDENLPLIVAIDLQPMAPIEGVIQVQGDITNARTAEVVIRHFDGCKANLVVCDGAP 129
+ I+A DL PM PI GV +QGD + + ++ K +V+ D AP
Sbjct: 74 GGKGR------IIACDLLPMDPIVGVDFLQGDFRDELVMKALLERVGDSKVQVVMSDMAP 127
Query: 130 DVTGLHDMDEFVQSQLILAGLTIVTHVLKEGGKFIAKIFRGKDTSLLYCQLKLFFPVVTF 189
+++G +D L+ L + VL GG F+ K+F+G+ +++ F V
Sbjct: 128 NMSGTPAVDIPRAMYLVELALEMCRDVLAPGGSFVVKVFQGEGFDEYLREIRSLFTKVKV 187
Query: 190 AKPKSSRNSSIEAFAVCENYSP 211
KP SSR S E + V P
Sbjct: 188 RKPDSSRARSREVYIVATGRKP 209
>RRMJ_HAEIN (P45162) Ribosomal RNA large subunit methyltransferase J
(EC 2.1.1.-) (rRNA (uridine-2'-O-)-methyltransferase)
(23S rRNA m2U2552 methyltransferase) (Cell division
protein ftsJ homolog)
Length = 209
Score = 91.7 bits (226), Expect = 2e-18
Identities = 58/200 (29%), Positives = 100/200 (50%), Gaps = 12/200 (6%)
Query: 10 DIYYRKAKEEGWRARSAFKLLQIDEEFNIFEGVKRVVDLCAAPGSWSQVLSRKLYLPAKL 69
D + +KA ++ R+R+ FK+ +I + +F+ VVDL AAPG WSQ Y+ +++
Sbjct: 20 DQFVQKAHKQKLRSRAYFKIDEIQQTDKLFKQGMTVVDLGAAPGGWSQ------YVVSQI 73
Query: 70 APDAKDENLPLIVAIDLQPMAPIEGVIQVQGDITNARTAEVVIRHFDGCKANLVVCDGAP 129
+ ++A D+ M PI GV +QGD + ++ K ++V+ D AP
Sbjct: 74 GGKGR------VIACDILEMDPIVGVDFLQGDFRDENVLNALLARVGEDKVDVVMSDMAP 127
Query: 130 DVTGLHDMDEFVQSQLILAGLTIVTHVLKEGGKFIAKIFRGKDTSLLYCQLKLFFPVVTF 189
+ +G+ +D L+ L + VL G F+ K+F+G+ +++ F VV
Sbjct: 128 NFSGMPSVDIPRAMYLVELALDMCKQVLASKGSFVVKVFQGEGFDEYLREIRSLFDVVKV 187
Query: 190 AKPKSSRNSSIEAFAVCENY 209
KP++SR S E + V Y
Sbjct: 188 RKPEASRGRSREVYIVATGY 207
>Y682_TREPA (O83687) Putative ribosomal RNA methyltransferase (EC
2.1.1.-) (rRNA (uridine-2'-O-)-methyltransferase)
Length = 200
Score = 86.7 bits (213), Expect = 7e-17
Identities = 64/203 (31%), Positives = 100/203 (48%), Gaps = 23/203 (11%)
Query: 8 KRDIYYRKAKEEGWRARSAFKLLQIDEEFNIFEGVKRVVDLCAAPGSWSQVLSRKLYLPA 67
+ D + +KA G+RARS +KL +D+++++ RV+DL AAPGSW+Q + L
Sbjct: 6 RADFWAKKAAAAGYRARSVYKLAALDKKYSLLSRASRVLDLGAAPGSWTQYV-----LGT 60
Query: 68 KLAPDAKDENLPLIVAIDLQPMA---PIEGVIQVQGDITNARTAEVVIRHFDGCKA--NL 122
A A + A+D+QP+A + +VQGD+ A T V C A +L
Sbjct: 61 AAACTA-------VCAVDVQPIASDIQDARLQRVQGDLCAADTRARV-----ACNAPFDL 108
Query: 123 VVCDGAPDVTGLHDMDEFVQSQLILAGLTIVTHVLKEGGKFIAKIFRGKDTSLLYCQLKL 182
++ D AP TG +D S + AG+ + L G + K+F+G + + L+
Sbjct: 109 ILSDAAPRTTGNRTVDTSA-SACLAAGVCAYVNFLSSDGGLVFKVFQGSEHLAILTHLRA 167
Query: 183 FFPVVTFAKPKSSRNSSIEAFAV 205
F V KP +SR S E + V
Sbjct: 168 HFGAVCSFKPPASRPRSCELYVV 190
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.319 0.139 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,682,997
Number of Sequences: 164201
Number of extensions: 1747895
Number of successful extensions: 3593
Number of sequences better than 10.0: 35
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 3518
Number of HSP's gapped (non-prelim): 38
length of query: 316
length of database: 59,974,054
effective HSP length: 110
effective length of query: 206
effective length of database: 41,911,944
effective search space: 8633860464
effective search space used: 8633860464
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Medicago: description of AC149135.13