BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC149079.11 - phase: 0
(664 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CAO1_RAT (P07872) Acyl-coenzyme A oxidase 1, peroxisomal (EC 1.3... 533 e-151
CAO1_MOUSE (Q9R0H0) Acyl-coenzyme A oxidase 1, peroxisomal (EC 1... 526 e-149
CAO1_CAVPO (Q9Z1N0) Acyl-coenzyme A oxidase 1, peroxisomal (EC 1... 526 e-149
CAO1_PHACI (Q8HYL8) Acyl-coenzyme A oxidase 1, peroxisomal (EC 1... 523 e-148
CAO1_HUMAN (Q15067) Acyl-coenzyme A oxidase 1, peroxisomal (EC 1... 515 e-145
CAO2_RABIT (O02767) Acyl-coenzyme A oxidase 2, peroxisomal (EC 1... 419 e-116
CAO2_HUMAN (Q99424) Acyl-coenzyme A oxidase 2, peroxisomal (EC 1... 419 e-116
CAO2_MOUSE (Q9QXD1) Acyl-coenzyme A oxidase 2, peroxisomal (EC 1... 418 e-116
CAO2_RAT (P97562) Acyl-coenzyme A oxidase 2, peroxisomal (EC 1.3... 410 e-114
CAOP_CAEEL (P34355) Probable acyl-coenzyme A oxidase, peroxisoma... 382 e-105
CAO4_CANMA (P05335) Acyl-coenzyme A oxidase POX4 (EC 1.3.3.6) (A... 308 4e-83
CAO2_CANTR (P06598) Acyl-coenzyme A oxidase II (EC 1.3.3.6) (Acy... 293 1e-78
CAO1_CANTR (P08790) Acyl-coenzyme A oxidase I (EC 1.3.3.6) (Acyl... 288 2e-77
CAO4_CANTR (P11356) Acyl-coenzyme A oxidase PXP-2 (EC 1.3.3.6) (... 286 9e-77
CAO3_HUMAN (O15254) Acyl-coenzyme A oxidase 3, peroxisomal (EC 1... 285 3e-76
CAO3_RAT (Q63448) Acyl-coenzyme A oxidase 3, peroxisomal (EC 1.3... 282 2e-75
CAO2_CANMA (Q00468) Acyl-coenzyme A oxidase POX2 (EC 1.3.3.6) (A... 263 8e-70
CAO3_MOUSE (Q9EPL9) Acyl-coenzyme A oxidase 3, peroxisomal (EC 1... 261 4e-69
CAO_YEAST (P13711) Acyl-coenzyme A oxidase (EC 1.3.3.6) (Acyl-Co... 250 1e-65
CAO3_CANTR (P11355) Acyl-coenzyme A oxidase POX4-2 (EC 1.3.3.6) ... 215 3e-55
>CAO1_RAT (P07872) Acyl-coenzyme A oxidase 1, peroxisomal (EC
1.3.3.6) (Palmitoyl-CoA oxidase) (AOX)
Length = 661
Score = 533 bits (1372), Expect = e-151
Identities = 290/661 (43%), Positives = 415/661 (61%), Gaps = 27/661 (4%)
Query: 10 ERNKAEFDVDAMKIVWAGSAHALEVSDRMSRLVASDPAFRKDHRPMLGRKELFKSTLKKA 69
ER A F+ + + + GS + L+ +DP F+ + L R + ++ +KK+
Sbjct: 8 ERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAVKKS 67
Query: 70 AYAWKRIIELRLTEEEASM------LRSFVDEPAFTDLHWGMFIPAIKGQGTEEQQQKWL 123
A K++ E +++ E M L +FV+ L++ MFIP + QGT QQ+KW+
Sbjct: 68 ATMVKKMREYGISDPEEIMWFKKLYLANFVEP---VGLNYSMFIPTLLNQGTTAQQEKWM 124
Query: 124 PLAQRMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHSPTLTSSKWWPGGLGKVS 183
+Q +QIIG YAQTE+GHG++++GLETTAT+DPKT EF+++SPT+TS KWWPGGLGK S
Sbjct: 125 RPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTS 184
Query: 184 THAVVYARLITDGRDHGVHGFIVQLRSLDDHLPLPGITVGDIGMKFGNGAYNTMDNGVLR 243
HA+V A+LIT G +G+H F+V +R + H PLPGITVGDIG KFG Y MDNG L+
Sbjct: 185 NHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFG---YEEMDNGYLK 241
Query: 244 FEHVRIPRDQMLMRVSQVTREGKYVQSNVPRQLVYGTMVYVRQTIVSDASTAMSRAVCIA 303
++ RIPR+ MLM+ +QV +G YV+ + +L YGTMV+VR +V +A+ ++S+A IA
Sbjct: 242 MDNYRIPRENMLMKYAQVKPDGTYVKP-LSNKLTYGTMVFVRSFLVGNAAQSLSKACTIA 300
Query: 304 ARYSAVRRQFGGNNGSLESQVIDYKTQQARLFPLLASAYAFRFVGEWLKWLYTDVMKRLQ 363
RYSAVRRQ E Q++D++TQQ +LFPLLA+AYAF FVG ++K Y + + +
Sbjct: 301 IRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIG 360
Query: 364 ANDFSTLPEAHACTAGLKSLTTSATSDGIEECRKLCGGHGYLCSSGLPELFAVYVPTCTY 423
D S LPE HA TAGLK+ TT + GIEECR CGGHGY SSG+P ++ + P CT+
Sbjct: 361 QGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTF 420
Query: 424 EGDNIVLLLQVARHLMKVISRLGSGKKPVGTTAYMGRVEQLLEARSDVQKAEDW---LNP 480
EG+N V++LQ AR LMK+ ++ SGK G +Y+ L R Q+ W ++
Sbjct: 421 EGENTVMMLQTARFLMKIYDQVRSGKLVGGMVSYL---NDLPSQRIQPQQVAVWPTMVDI 477
Query: 481 NT---VLRAFEARAARMSVACAKNL----TKFSNPEEGFQELLADLVDAARAHCQLIVVS 533
N+ + A++ RAAR+ AKNL + + E + DLV A+ AHC +VV
Sbjct: 478 NSLEGLTEAYKLRAARLVEIAAKNLQTHVSHRKSKEVAWNLTSVDLVRASEAHCHYVVVK 537
Query: 534 KFIEKLQQDIPGKGVKRQLEILCNIYALFHLHKHLGDFLSTGCITPKQGSLANDQLRSLY 593
F +KL + I K V+ L LC +Y+L+ + + GDFL IT Q S N ++ L
Sbjct: 538 VFSDKLPK-IQDKAVQAVLRNLCLLYSLYGISQKGGDFLEGSIITGAQLSQVNARILELL 596
Query: 594 SQVRPNAIALVDAFNYTDHYLSSVLGRYDGNVYPKLYEEAWKDPLNDSVVPDGFQEYIRP 653
+ +RPNA+ALVDAF++ D L SVLGRYDGNVY L+E A K PLN + V + + ++++P
Sbjct: 597 TLIRPNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHESYHKHLKP 656
Query: 654 M 654
+
Sbjct: 657 L 657
>CAO1_MOUSE (Q9R0H0) Acyl-coenzyme A oxidase 1, peroxisomal (EC
1.3.3.6) (Palmitoyl-CoA oxidase) (AOX)
Length = 661
Score = 526 bits (1356), Expect = e-149
Identities = 286/658 (43%), Positives = 408/658 (61%), Gaps = 21/658 (3%)
Query: 10 ERNKAEFDVDAMKIVWAGSAHALEVSDRMSRLVASDPAFRKDHRPMLGRKELFKSTLKKA 69
ER A F+ + + V GS + L+ +DP F+ + L R + ++ +KK+
Sbjct: 8 ERAAATFNPELITHVLDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAVKKS 67
Query: 70 AYAWKRIIELRLTEEEASMLRSFVDEPAFTD---LHWGMFIPAIKGQGTEEQQQKWLPLA 126
A K++ E + + E M + F + L++ MFIP + QGT QQ+KW+ +
Sbjct: 68 ATMVKKMREFGIADPEEIMWFKKLHMVNFVEPVGLNYSMFIPTLLNQGTTAQQEKWMHPS 127
Query: 127 QRMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHSPTLTSSKWWPGGLGKVSTHA 186
Q +QIIG YAQTE+GHG++++GLETTAT+DPKT EF+++SPT+TS KWWPGGLGK S HA
Sbjct: 128 QELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHA 187
Query: 187 VVYARLITDGRDHGVHGFIVQLRSLDDHLPLPGITVGDIGMKFGNGAYNTMDNGVLRFEH 246
+V A+LIT G +G+H F+V +R + H PLPGITVGDIG KFG Y MDNG L+ ++
Sbjct: 188 IVLAQLITRGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFG---YEEMDNGYLKMDN 244
Query: 247 VRIPRDQMLMRVSQVTREGKYVQSNVPRQLVYGTMVYVRQTIVSDASTAMSRAVCIAARY 306
RIPR+ MLM+ +QV +G YV+ + +L YGTMV+VR +V A+ ++S+A IA RY
Sbjct: 245 YRIPRENMLMKYAQVKPDGTYVKP-LSNKLTYGTMVFVRSFLVGSAAQSLSKACTIAIRY 303
Query: 307 SAVRRQFGGNNGSLESQVIDYKTQQARLFPLLASAYAFRFVGEWLKWLYTDVMKRLQAND 366
SAVRRQ E Q++D++TQQ +LFPLLA+AYAF F+G ++K Y + + + D
Sbjct: 304 SAVRRQSEIKRSEPEPQILDFQTQQYKLFPLLATAYAFHFLGRYIKETYMRINESIGQGD 363
Query: 367 FSTLPEAHACTAGLKSLTTSATSDGIEECRKLCGGHGYLCSSGLPELFAVYVPTCTYEGD 426
S LPE HA TAGLK+ TT + GIEECR CGGHGY SSG+P ++ + P CT+EG+
Sbjct: 364 LSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGE 423
Query: 427 NIVLLLQVARHLMKVISRLGSGKKPVGTTAYMGRVEQLLEARSDVQKAEDW-----LNP- 480
N V++LQ AR LMK+ ++ SGK G +Y+ L R Q+ W +N
Sbjct: 424 NTVMMLQTARFLMKIYDQVQSGKLVGGMVSYL---NDLPSQRIQPQQVAVWPTLVDINSL 480
Query: 481 NTVLRAFEARAARMSVACAKNL----TKFSNPEEGFQELLADLVDAARAHCQLIVVSKFI 536
+++ A++ RAAR+ AKNL + + E + DLV A+ AHC + V F
Sbjct: 481 DSLTEAYKLRAARLVEIAAKNLQAQVSHRKSKEVAWNLTSVDLVRASEAHCHYVTVKVFA 540
Query: 537 EKLQQDIPGKGVKRQLEILCNIYALFHLHKHLGDFLSTGCITPKQGSLANDQLRSLYSQV 596
+KL + I + V+ L LC +Y+L+ + + GDFL IT Q S N ++ L +
Sbjct: 541 DKLPK-IQDRAVQAVLRNLCLLYSLYGISQKGGDFLEGNIITGAQMSQVNSRILELLTVT 599
Query: 597 RPNAIALVDAFNYTDHYLSSVLGRYDGNVYPKLYEEAWKDPLNDSVVPDGFQEYIRPM 654
RPNA+ALVDAF++ D L SVLGRYDGNVY L+E A K PLN + V + ++++P+
Sbjct: 600 RPNAVALVDAFDFKDVTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHQSYYKHLKPL 657
>CAO1_CAVPO (Q9Z1N0) Acyl-coenzyme A oxidase 1, peroxisomal (EC
1.3.3.6) (Palmitoyl-CoA oxidase) (AOX)
Length = 661
Score = 526 bits (1355), Expect = e-149
Identities = 289/661 (43%), Positives = 410/661 (61%), Gaps = 27/661 (4%)
Query: 10 ERNKAEFDVDAMKIVWAGSAHALEVSDRMSRLVASDPAFRKDHRPMLGRKELFKSTLKKA 69
ER A F+ + + + GS + + SDP F+ ++ L R E +++ +KK+
Sbjct: 8 ERAAATFNPELITHLLDGSPEKTRRRREIENKILSDPDFQHENHNFLTRSERYEAAIKKS 67
Query: 70 AYAWKRIIELRLTEEEASM------LRSFVDEPAFTDLHWGMFIPAIKGQGTEEQQQKWL 123
A K++ E + + + M L +FV+ L++ MFIP + QGT QQ+KWL
Sbjct: 68 AVMVKKMREFGIADPDEIMWFKRLLLGNFVEP---VGLNYSMFIPTLLNQGTTAQQEKWL 124
Query: 124 PLAQRMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHSPTLTSSKWWPGGLGKVS 183
+ +QIIG YAQTE+GHG++++GLETTAT+DPKT EF+I+SPT+TS KWWPGGLGK S
Sbjct: 125 HPSTGLQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFIINSPTVTSIKWWPGGLGKTS 184
Query: 184 THAVVYARLITDGRDHGVHGFIVQLRSLDDHLPLPGITVGDIGMKFGNGAYNTMDNGVLR 243
HA+V A+LIT G+ +G+H FIV +R + H PLPGITVGDIG KFG Y MDNG L+
Sbjct: 185 NHAIVLAQLITQGKCYGLHAFIVPIREIGTHKPLPGITVGDIGPKFG---YEEMDNGYLK 241
Query: 244 FEHVRIPRDQMLMRVSQVTREGKYVQSNVPRQLVYGTMVYVRQTIVSDASTAMSRAVCIA 303
++ RIPR+ MLM+ +QV +G YV+ V +L YGTMV+VR +V A+ ++S+A IA
Sbjct: 242 MDNYRIPRENMLMKYAQVKPDGTYVKP-VSNKLTYGTMVFVRSFLVGAAAQSLSKACTIA 300
Query: 304 ARYSAVRRQFGGNNGSLESQVIDYKTQQARLFPLLASAYAFRFVGEWLKWLYTDVMKRLQ 363
RYSAVR Q G E QV+D++TQQ +LFP+LA+AYAF+FVG ++K Y + + +
Sbjct: 301 IRYSAVRHQSEIKPGEPEPQVLDFQTQQYKLFPILATAYAFQFVGSYMKDTYHRINESIG 360
Query: 364 ANDFSTLPEAHACTAGLKSLTTSATSDGIEECRKLCGGHGYLCSSGLPELFAVYVPTCTY 423
D S LPE HA TAGLK+ TT + GIEECR CGGHGY SG+P ++ + P CT+
Sbjct: 361 QGDLSELPELHALTAGLKAFTTWTANAGIEECRLACGGHGYSHCSGIPNIYVTFTPACTF 420
Query: 424 EGDNIVLLLQVARHLMKVISRLGSGKKPVGTTAYMGRVEQLLEARSDVQKAEDW------ 477
EG+N V++LQ AR LMKV ++ SGK G +Y+ L R Q+ W
Sbjct: 421 EGENTVMMLQTARFLMKVYDQVQSGKLVHGLVSYL---NDLPSQRIQPQQVAVWPTVVDI 477
Query: 478 LNPNTVLRAFEARAARMSVACAKNL----TKFSNPEEGFQELLADLVDAARAHCQLIVVS 533
NP+++ ++ RAAR+ AK+L + + E + LV A AHC +VV
Sbjct: 478 NNPDSLTEIYKLRAARLIDIAAKSLQGEMSHRKSKEVAWNLTSVGLVRATDAHCHYVVVK 537
Query: 534 KFIEKLQQDIPGKGVKRQLEILCNIYALFHLHKHLGDFLSTGCITPKQGSLANDQLRSLY 593
F +KL + I K ++ L L +Y+L+ + + GDFL +T Q + N ++ L
Sbjct: 538 LFADKLLK-IQDKTIQAVLRNLFLLYSLYGISQKAGDFLQGNIMTGSQITQVNQRVLELL 596
Query: 594 SQVRPNAIALVDAFNYTDHYLSSVLGRYDGNVYPKLYEEAWKDPLNDSVVPDGFQEYIRP 653
+ +RPNA+ALVDAF+Y D L SVLGRYDGNVY L+E A K PLN + V + + +Y++P
Sbjct: 597 AVIRPNAVALVDAFDYKDITLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHESYHKYLKP 656
Query: 654 M 654
+
Sbjct: 657 L 657
>CAO1_PHACI (Q8HYL8) Acyl-coenzyme A oxidase 1, peroxisomal (EC
1.3.3.6) (Palmitoyl-CoA oxidase) (AOX)
Length = 661
Score = 523 bits (1347), Expect = e-148
Identities = 278/658 (42%), Positives = 410/658 (62%), Gaps = 21/658 (3%)
Query: 10 ERNKAEFDVDAMKIVWAGSAHALEVSDRMSRLVASDPAFRKDHRPMLGRKELFKSTLKKA 69
ER+ A FD + + + G + + L+ +DP F+ + L R E ++ ++K+
Sbjct: 8 ERDAASFDAEKLTYILDGGSERTRRRREIENLILNDPDFKHEDLNFLTRSERYEIAVRKS 67
Query: 70 AYAWKRIIELRLTE-EEASMLRSFVDE--PAFTDLHWGMFIPAIKGQGTEEQQQKWLPLA 126
A K++ + + + EE ++FV P DLH GMF+P + Q T+EQQ+++ A
Sbjct: 68 ATMVKKMRDFGIADPEEIMWFKNFVHRGRPEPLDLHLGMFLPTLLHQATQEQQERFFIPA 127
Query: 127 QRMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHSPTLTSSKWWPGGLGKVSTHA 186
++IIG YAQTE+GHG++++GLETTAT+DPKT EF+++SPT+TS KWWPGGLGK S HA
Sbjct: 128 WNLEIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHA 187
Query: 187 VVYARLITDGRDHGVHGFIVQLRSLDDHLPLPGITVGDIGMKFGNGAYNTMDNGVLRFEH 246
+V A+L T G +G+H FIV +R + H P PGI VGDIG KFG Y+ MDNG L+ ++
Sbjct: 188 IVLAQLYTKGECYGLHAFIVPIREMGTHKPFPGIIVGDIGPKFG---YDEMDNGYLKMDN 244
Query: 247 VRIPRDQMLMRVSQVTREGKYVQSNVPRQLVYGTMVYVRQTIVSDASTAMSRAVCIAARY 306
RIPR+ MLM+ +QV +G YV+ + +L YGTMV+VR +V +A+ ++S+A IA RY
Sbjct: 245 YRIPRENMLMKYAQVKPDGTYVKP-LSNKLTYGTMVFVRSFLVGEAARSLSKACTIAIRY 303
Query: 307 SAVRRQFGGNNGSLESQVIDYKTQQARLFPLLASAYAFRFVGEWLKWLYTDVMKRLQAND 366
S +R Q G E Q++D++TQQ +LFPLLA+AYAF+FVG ++K Y + + +
Sbjct: 304 SLIRHQSEIQPGDPEPQILDFQTQQYKLFPLLATAYAFQFVGAYMKETYHRINVDISQGN 363
Query: 367 FSTLPEAHACTAGLKSLTTSATSDGIEECRKLCGGHGYLCSSGLPELFAVYVPTCTYEGD 426
+ LPE HA TAGLK+ T+ T+ GIE CR CGGHGY SGLP ++ + PTCT+EG+
Sbjct: 364 LNELPELHALTAGLKAFTSWTTNSGIEACRMACGGHGYSHCSGLPNIYVTFTPTCTFEGE 423
Query: 427 NIVLLLQVARHLMKVISRLGSGKKPVGTTAYMGRVEQLLEARSDVQKAEDW------LNP 480
N V++LQ AR LMK ++ SGK G +Y+ L R Q+ W NP
Sbjct: 424 NTVMMLQTARFLMKSYDQVHSGKLVGGMVSYL---NDLPSQRIQPQQVAAWPAMVDINNP 480
Query: 481 NTVLRAFEARAARMSVACAKNL----TKFSNPEEGFQELLADLVDAARAHCQLIVVSKFI 536
+++ A++ RAAR+ A A+NL + E + DLV A+ AHC +VV F
Sbjct: 481 DSLTEAYKHRAARLVEAAARNLQAEMKHRKSKEIAWNFTSVDLVRASEAHCHYVVVKLFS 540
Query: 537 EKLQQDIPGKGVKRQLEILCNIYALFHLHKHLGDFLSTGCITPKQGSLANDQLRSLYSQV 596
L + I K ++ L LC +YAL+ + ++ GDFL G +T Q + N +++ L + +
Sbjct: 541 GNLSK-IDDKPIQAVLTNLCLLYALYGISQNSGDFLQGGILTESQLTQVNQRVKELLTLI 599
Query: 597 RPNAIALVDAFNYTDHYLSSVLGRYDGNVYPKLYEEAWKDPLNDSVVPDGFQEYIRPM 654
RP + ALVDAF++ D L SVLGRYDGN+Y ++E A K PLN S V + + ++++P+
Sbjct: 600 RPESAALVDAFDFQDVSLGSVLGRYDGNIYENMFEWAKKSPLNKSEVHESYHKHLKPL 657
>CAO1_HUMAN (Q15067) Acyl-coenzyme A oxidase 1, peroxisomal (EC
1.3.3.6) (Palmitoyl-CoA oxidase) (AOX)
Length = 660
Score = 515 bits (1327), Expect = e-145
Identities = 279/655 (42%), Positives = 410/655 (62%), Gaps = 27/655 (4%)
Query: 10 ERNKAEFDVDAMKIVWAGSAHALEVSDRMSRLVASDPAFRKDHRPMLGRKELFKSTLKKA 69
ER+ A F+ + + + GS + ++ +DP F+ + L R + ++ ++K+
Sbjct: 8 ERDSASFNPELLTHILDGSPEKTRRRREIENMILNDPDFQHEDLNFLTRSQRYEVAVRKS 67
Query: 70 AYAWKRIIELRLTEEEASM------LRSFVDEPAFTDLHWGMFIPAIKGQGTEEQQQKWL 123
A K++ E + + + M L +FV+ L++ MFIP + QGT Q++KWL
Sbjct: 68 AIMVKKMREFGIADPDEIMWFKKLHLVNFVEP---VGLNYSMFIPTLLNQGTTAQKEKWL 124
Query: 124 PLAQRMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHSPTLTSSKWWPGGLGKVS 183
++ +QIIG YAQTE+GHG++++GLETTAT+DP+T EF+++SPT+TS KWWPGGLGK S
Sbjct: 125 LSSKGLQIIGTYAQTEMGHGTHLRGLETTATYDPETQEFILNSPTVTSIKWWPGGLGKTS 184
Query: 184 THAVVYARLITDGRDHGVHGFIVQLRSLDDHLPLPGITVGDIGMKFGNGAYNTMDNGVLR 243
HA+V A+LIT G+ +G+H FIV +R + H PLPGITVGDIG KFG Y+ +DNG L+
Sbjct: 185 NHAIVLAQLITKGKCYGLHAFIVPIREIGTHKPLPGITVGDIGPKFG---YDEIDNGYLK 241
Query: 244 FEHVRIPRDQMLMRVSQVTREGKYVQSNVPRQLVYGTMVYVRQTIVSDASTAMSRAVCIA 303
++ RIPR+ MLM+ +QV +G YV+ + +L YGTMV+VR +V +A+ A+S+A IA
Sbjct: 242 MDNHRIPRENMLMKYAQVKPDGTYVKP-LSNKLTYGTMVFVRSFLVGEAARALSKACTIA 300
Query: 304 ARYSAVRRQFGGNNGSLESQVIDYKTQQARLFPLLASAYAFRFVGEWLKWLYTDVMKRLQ 363
RYSAVR Q G E Q++D++TQQ +LFPLLA+AYAF+FVG ++K Y + + +
Sbjct: 301 IRYSAVRHQSEMKPGEPEPQILDFQTQQYKLFPLLATAYAFQFVGAYMKETYHRINEGIG 360
Query: 364 ANDFSTLPEAHACTAGLKSLTTSATSDGIEECRKLCGGHGYLCSSGLPELFAVYVPTCTY 423
D S LPE HA TAGLK+ T+ + GIE CR CGGHGY SGLP ++ + P+CT+
Sbjct: 361 QGDLSELPELHALTAGLKAFTSWTANTGIEACRMACGGHGYSHCSGLPNIYVNFTPSCTF 420
Query: 424 EGDNIVLLLQVARHLMKVISRLGSGKKPVGTTAYMGRVEQLLEARSDVQKAEDW------ 477
EG+N V++LQ AR LMK ++ SGK G +Y+ L R Q+ W
Sbjct: 421 EGENTVMMLQTARFLMKSYDQVHSGKLVCGMVSYL---NDLPSQRIQPQQVAVWPTMVDI 477
Query: 478 LNPNTVLRAFEARAARMSVACAKNLTK----FSNPEEGFQELLADLVDAARAHCQLIVVS 533
+P ++ A++ RAAR+ AKNL K + E + DLV A+ AHC +VV
Sbjct: 478 NSPESLTEAYKLRAARLVEIAAKNLQKEVIHRKSKEVAWNLTSVDLVRASEAHCHYVVVK 537
Query: 534 KFIEKLQQDIPGKGVKRQLEILCNIYALFHLHKHLGDFLSTGCITPKQGSLANDQLRSLY 593
F EKL + I K ++ L LC +Y+L+ + ++ GDFL +T Q + N +++ L
Sbjct: 538 LFSEKLLK-IQDKAIQAVLRSLCLLYSLYGISQNAGDFLQGSIMTEPQITQVNQRVKELL 596
Query: 594 SQVRPNAIALVDAFNYTDHYLSSVLGRYDGNVYPKLYEEAWKDPLNDSVVPDGFQ 648
+ +R +A+ALVDAF++ D L SVLGRYDGNVY L+E A PLN + V + ++
Sbjct: 597 TLIRSDAVALVDAFDFQDVTLGSVLGRYDGNVYENLFEWAKNSPLNKAEVHESYK 651
>CAO2_RABIT (O02767) Acyl-coenzyme A oxidase 2, peroxisomal (EC
1.3.3.6) (Branched-chain acyl-CoA oxidase) (BRCACox)
(Trihydroxycoprostanoyl-CoA oxidase) (THCCox) (THCA-CoA
oxidase) (3alpha,7alpha,
12alpha-trihydroxy-5beta-cholestanoyl-CoA oxidase)
Length = 681
Score = 419 bits (1076), Expect = e-116
Identities = 241/662 (36%), Positives = 360/662 (53%), Gaps = 16/662 (2%)
Query: 10 ERNKAEFDVDAMKIVWAGSAHALEVSDRMSRLVASDPAFRKDHRPMLGRKELFKSTLKKA 69
ER F V+ + + G A + ++ ++ +P F + + EL+++ +K
Sbjct: 25 ERCAQSFSVERLTNILDGGAQHTALRRKVESIIHGNPQFSSKDNYFMSQNELYEAATRKR 84
Query: 70 AYAWKRIIELRLTEEEASMLRSFVDEPAFTDLHW---GMFIPAIKGQGTEEQQQKWLPLA 126
+ K + TEE + + DL+ G+F+ A++ G+EEQ KW PL
Sbjct: 85 YHLQKIAQRMGWTEEGREL--EYAHRALSADLNLNLQGIFLKALRSLGSEEQIAKWEPLG 142
Query: 127 QRMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHSPTLTSSKWWPGGLGKVSTHA 186
+ QII YAQTELGHG+ +QGLET AT+D T EFVIHSPT+T++KWWPG LG+ +THA
Sbjct: 143 KTFQIISTYAQTELGHGTYLQGLETEATYDAATQEFVIHSPTVTATKWWPGDLGRSATHA 202
Query: 187 VVYARLITDGRDHGVHGFIVQLRSLDDHLPLPGITVGDIGMKFGNGAYNTMDNGVLRFEH 246
++ A+LI G G+H FIV +RSL DH PLPGIT+GDIG K G +DNG L+ +H
Sbjct: 203 LILAQLICSGARRGMHAFIVPVRSLQDHTPLPGITIGDIGPKMG---LQHIDNGFLKMDH 259
Query: 247 VRIPRDQMLMRVSQVTREGKYVQSNVPRQLVYGTMVYVRQTIVSDASTAMSRAVCIAARY 306
VR+PR+ ML R +QV +G Y++ + G +V ++ + + +A IA RY
Sbjct: 260 VRVPRENMLSRFAQVLPDGAYIKLGTAQSNYLGMLVTRVHLLLGAILSPLQKACVIATRY 319
Query: 307 SAVRRQFGGNNGSLESQVIDYKTQQARLFPLLASAYAFRFVGEWLKWLYTDVMKRLQAND 366
S +R Q E ++++++TQQ +LFP LA YAF F+ L + K + D
Sbjct: 320 SVIRHQCRLRPSDPEVKILEHQTQQQKLFPQLAMCYAFHFLATGLLEFFQQAYKNILDRD 379
Query: 367 FSTLPEAHACTAGLKSLTTSATSDGIEECRKLCGGHGYLCSSGLPELFAVYVPTCTYEGD 426
F+ LPE HA + G K++ + + G E+CR+ CGGHGY SGLP L +CTYEG+
Sbjct: 380 FTLLPELHALSTGTKAMMSDFCTQGAEQCRRACGGHGYSKLSGLPSLVTSVTASCTYEGE 439
Query: 427 NIVLLLQVARHLMKVISRLGSGKKPVGTTAYMGRVEQLL---EARSDVQKAEDWLNPNTV 483
N VL LQVAR L+K + + V L AR Q A D+ P
Sbjct: 440 NTVLYLQVARFLVKSCLQAQGFPGSTSQRSLPRSVSYLALPDLARCPAQTAADFFCPALY 499
Query: 484 LRAFEARAARMSVACAKNLTKF----SNPEEGFQELLADLVDAARAHCQLIVVSKFIEKL 539
A+ AAR++ +L ++ E + + + AA+AHC I V F E L
Sbjct: 500 TAAWAHVAARLTKDSVHHLQALRQSGADEHEAWNQTTIIHLQAAKAHCYYISVKSFKEAL 559
Query: 540 QQDIPGKGVKRQLEILCNIYALFHLHKHLGDFLSTGCITPKQGSLANDQLRSLYSQVRPN 599
++ +++ L+ LC+++AL + + GDFL G ++ Q +A L +R +
Sbjct: 560 EKLENEPAIQQVLKRLCDLHALHGILTNSGDFLHDGFLSGAQVDMARTAYMDLLPLIRKD 619
Query: 600 AIALVDAFNYTDHYLSSVLGRYDGNVYPKLYEEAWKDPLNDSVVPDGFQEYIRPMLKQQL 659
AI L DAF++TD L+S LG YDGNVY +L+E A + P N P +++YI+P+L+
Sbjct: 620 AILLTDAFDFTDQCLNSALGCYDGNVYERLFEWAQRSPTNTQENP-AYKKYIQPLLQSWR 678
Query: 660 RN 661
N
Sbjct: 679 SN 680
>CAO2_HUMAN (Q99424) Acyl-coenzyme A oxidase 2, peroxisomal (EC
1.3.3.6) (Branched-chain acyl-CoA oxidase) (BRCACox)
(Trihydroxycoprostanoyl-CoA oxidase) (THCCox) (THCA-CoA
oxidase)
Length = 681
Score = 419 bits (1076), Expect = e-116
Identities = 256/665 (38%), Positives = 377/665 (56%), Gaps = 32/665 (4%)
Query: 10 ERNKAEFDVDAMKIVWAGSAHALEVSDRMSRLVASDPAFRKDHRPMLGRKELFKSTLKKA 69
ER FDV+ + + G A + ++ ++ S P F + + E +K+ +++A
Sbjct: 25 ERYMQSFDVERLTNILDGGAQNTALRRKVESIIHSYPEFSCKDNYFMTQNERYKAAMRRA 84
Query: 70 AYAWKRIIELRLTEEEASMLRSFVDEPAFTDLHWGM---FIPAIKGQGTEEQQQKWLPLA 126
+ R+I RL E + D+ + F+ A++ G+EEQ KW PL
Sbjct: 85 FHI--RLIARRLGWLEDGRELGYAYRALSGDVALNIHRVFVRALRSLGSEEQIAKWDPLC 142
Query: 127 QRMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHSPTLTSSKWWPGGLGKVSTHA 186
+ +QII YAQTELGHG+ +QGLET AT+D T EFVIHSPTLT++KWWPG LG+ +THA
Sbjct: 143 KNIQIIATYAQTELGHGTYLQGLETEATYDAATQEFVIHSPTLTATKWWPGDLGRSATHA 202
Query: 187 VVYARLITDGRDHGVHGFIVQLRSLDDHLPLPGITVGDIGMKFGNGAYNTMDNGVLRFEH 246
+V A+LI G G+H FIV +RSL DH PLPGI +GDIG K ++ DNG L+ H
Sbjct: 203 LVQAQLICSGARRGMHAFIVPIRSLQDHTPLPGIIIGDIGPKMD---FDQTDNGFLQLNH 259
Query: 247 VRIPRDQMLMRVSQVTREGKYVQSNVPRQLVYGTMVYVRQTIVS-DASTAMSRAVCIAAR 305
VR+PR+ ML R +QV +G YV+ Q Y MV VR ++S + + +A IA R
Sbjct: 260 VRVPRENMLSRFAQVLPDGTYVKLGT-AQSNYLPMVVVRVELLSGEILPILQKACVIAMR 318
Query: 306 YSAVRRQFGGNNGSLESQVIDYKTQQARLFPLLASAYAFRFVG----EWLKWLYTDVMKR 361
YS +RRQ E++V+DY+TQQ +LFP LA +YAF F+ E+ + YT ++ +
Sbjct: 319 YSVIRRQSRLRPSDPEAKVLDYQTQQQKLFPQLAISYAFHFLAVSLLEFFQHSYTAILNQ 378
Query: 362 LQANDFSTLPEAHACTAGLKSLTTSATSDGIEECRKLCGGHGYLCSSGLPELFAVYVPTC 421
DFS LPE HA + G+K++ + + G E CR+ CGGHGY SGLP L +C
Sbjct: 379 ----DFSFLPELHALSTGMKAMMSEFCTQGAEMCRRACGGHGYSKLSGLPSLVTKLSASC 434
Query: 422 TYEGDNIVLLLQVARHLMK--VISRLGSGKKP----VGTTAYMGRVEQLLEARSDVQKAE 475
TYEG+N VL LQVAR L+K + +++ G P + AY+ + AR Q+A
Sbjct: 435 TYEGENTVLYLQVARFLVKSYLQTQMSPGSTPQRSLSPSVAYLTAPDL---ARCPAQRAA 491
Query: 476 DWLNPNTVLRAFEARAARM---SVACAKNLTKF-SNPEEGFQELLADLVDAARAHCQLIV 531
D+L P A+ A R+ SV + LT+ ++ E + + + AA+ HC +
Sbjct: 492 DFLCPELYTTAWAHVAVRLIKDSVQHLQTLTQSGADQHEAWNQTTVIHLQAAKVHCYYVT 551
Query: 532 VSKFIEKLQQDIPGKGVKRQLEILCNIYALFHLHKHLGDFLSTGCITPKQGSLANDQLRS 591
V F E L++ +++ L+ LC+++A+ + + GDFL ++ Q +A
Sbjct: 552 VKGFTEALEKLENEPAIQQVLKRLCDLHAIHGILTNSGDFLHDAFLSGAQVDMARTAYLD 611
Query: 592 LYSQVRPNAIALVDAFNYTDHYLSSVLGRYDGNVYPKLYEEAWKDPLNDSVVPDGFQEYI 651
L +R +AI L DAF++TD L+S LG YDGNVY +L++ A K P N P ++EYI
Sbjct: 612 LLRLIRKDAILLTDAFDFTDQCLNSALGCYDGNVYERLFQWAQKSPTNTQENP-AYEEYI 670
Query: 652 RPMLK 656
RP+L+
Sbjct: 671 RPLLQ 675
>CAO2_MOUSE (Q9QXD1) Acyl-coenzyme A oxidase 2, peroxisomal (EC
1.3.3.6) (Branched-chain acyl-CoA oxidase) (BRCACox)
(Trihydroxycoprostanoyl-CoA oxidase) (THCCox) (THCA-CoA
oxidase)
Length = 681
Score = 418 bits (1074), Expect = e-116
Identities = 250/662 (37%), Positives = 369/662 (54%), Gaps = 26/662 (3%)
Query: 10 ERNKAEFDVDAMKIVWAGSAHALEVSDRMSRLVASDPAFRKDHRPMLGRKELFKSTLKKA 69
E + F V+ + + G E+ R+ L+ DP F H + R EL++ ++K
Sbjct: 25 EWHSPSFSVERLTNILDGGIPNTELRRRVESLIQRDPVFNLKHLYFMTRDELYEDAVQKR 84
Query: 70 AYAWKRIIELRLTEEEASMLRSFVDEPAFTDLHW-GMFIPAIKGQGTEEQQQKWLPLAQR 128
+ K L +E+ + + + +L+ G+ + AI+ G++EQ KW L +
Sbjct: 85 FHLEKLAWSLGWSEDGPERIYADRVLAGYNNLNLHGIAMNAIRSLGSDEQIAKWGQLGKN 144
Query: 129 MQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHSPTLTSSKWWPGGLGKVSTHAVV 188
QII YAQTELGHG+ +QGLET AT+D T EFVIHSPT+TS KWWPG LG+ THAVV
Sbjct: 145 FQIITTYAQTELGHGTYLQGLETEATYDATTQEFVIHSPTMTSIKWWPGDLGRTVTHAVV 204
Query: 189 YARLITDGRDHGVHGFIVQLRSLDDHLPLPGITVGDIGMKFGNGAYNTMDNGVLRFEHVR 248
A LI G HG+H FIV +RSL+DH PLPGITVGDIG K G + +DNG LR HVR
Sbjct: 205 LAHLICLGARHGMHAFIVPIRSLEDHTPLPGITVGDIGPKMG---FENIDNGFLRLNHVR 261
Query: 249 IPRDQMLMRVSQVTREGKYVQSNVPRQLVYGTMVYVRQTIVSDASTAMSRAVCIAARYSA 308
+PR+ ML R ++V +G Y + P+ G +V Q + + +A IA RY+
Sbjct: 262 VPRENMLSRFAEVLPDGTYQRLGTPQSNYLGMLVTRVQLLYKGFLPTLQKACTIAVRYAV 321
Query: 309 VRRQFGGNNGSLESQVIDYKTQQARLFPLLASAYAFRFVG----EWLKWLYTDVMKRLQA 364
+R Q E+++++Y+TQQ +L P LA +YA F+ ++ Y+D++KR
Sbjct: 322 IRHQSRLRPSDPEAKILEYQTQQQKLLPQLAVSYALHFMTTSLLQFFHSSYSDILKR--- 378
Query: 365 NDFSTLPEAHACTAGLKSLTTSATSDGIEECRKLCGGHGYLCSSGLPELFAVYVPTCTYE 424
DFS LPE HA + G+K++++ + G E CR+ CGGHGY SGLP L + +CTYE
Sbjct: 379 -DFSLLPELHALSTGMKAMSSDFCAQGTEICRRACGGHGYSKLSGLPTLVTQAIASCTYE 437
Query: 425 GDNIVLLLQVARHLMK-----VISRLGSGKKPV-GTTAYMGRVEQLLEARSDVQKAEDWL 478
G+N VL LQVAR LMK +S +KP+ + Y+ AR Q A D+
Sbjct: 438 GENTVLYLQVARFLMKSYLQAQVSPGSIPQKPLPQSVMYLATPR---PARCPAQTAADFR 494
Query: 479 NPNTVLRAF---EARAARMSVACAKNLTKFS-NPEEGFQELLADLVDAARAHCQLIVVSK 534
P A+ AR R + + L + + + + + + AA+AHC + V
Sbjct: 495 CPEVYTTAWAYVSARLIRDATQHTQTLMRSGVDQYDAWNQTSVIHLQAAKAHCYFLTVRN 554
Query: 535 FIEKLQQDIPGKGVKRQLEILCNIYALFHLHKHLGDFLSTGCITPKQGSLANDQLRSLYS 594
F E +++ ++R L+ LC++YAL + + GDFL G ++ Q +A L
Sbjct: 555 FKEAVEKLDNEPEIQRVLQNLCDLYALNGILTNSGDFLHDGFLSGAQVDMARTAFLDLLP 614
Query: 595 QVRPNAIALVDAFNYTDHYLSSVLGRYDGNVYPKLYEEAWKDPLNDSVVPDGFQEYIRPM 654
+R +AI L DAF+++DH L+S LG YDG+VY +L+E A K P N P +++YIRP+
Sbjct: 615 LIRKDAILLTDAFDFSDHCLNSALGCYDGHVYQRLFEWAQKSPANTQENP-AYKKYIRPL 673
Query: 655 LK 656
++
Sbjct: 674 MQ 675
>CAO2_RAT (P97562) Acyl-coenzyme A oxidase 2, peroxisomal (EC
1.3.3.6) (Branched-chain acyl-CoA oxidase) (BRCACox)
(Trihydroxycoprostanoyl-CoA oxidase) (THCCox) (THCA-CoA
oxidase)
Length = 681
Score = 410 bits (1054), Expect = e-114
Identities = 249/658 (37%), Positives = 358/658 (53%), Gaps = 20/658 (3%)
Query: 10 ERNKAEFDVDAMKIVWAGSAHALEVSDRMSRLVASDPAFRKDHRPMLGRKELFKSTLKKA 69
ER+ F V+ + + G + ++ ++ SDP F + R+EL++ ++K
Sbjct: 25 ERHSPSFSVERLTNILDGGLPNTVLRRKVESIIQSDPVFNLKKLYFMTREELYEDAIQKR 84
Query: 70 AYAWKRIIELRLTEE--EASMLRSFVDEPAFTDLHWGMFIPAIKGQGTEEQQQKWLPLAQ 127
+ K L +E+ E +D LH G+ + AI+ G++EQ KW L +
Sbjct: 85 FHLEKLAWSLGWSEDGPERIYANRVLDGNVNLSLH-GVAMNAIRSLGSDEQIAKWGQLCK 143
Query: 128 RMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHSPTLTSSKWWPGGLGKVSTHAV 187
QII YAQTELGHG+ +QGLET AT+D E VIHSPT+TS+KWWPG LG THAV
Sbjct: 144 NFQIITTYAQTELGHGTYLQGLETEATYDEARQELVIHSPTMTSTKWWPGDLGWSVTHAV 203
Query: 188 VYARLITDGRDHGVHGFIVQLRSLDDHLPLPGITVGDIGMKFGNGAYNTMDNGVLRFEHV 247
V A+L G HG+H FIV +RSL+DH PLPGITVGDIG K G +DNG L+ HV
Sbjct: 204 VLAQLTCLGVRHGMHAFIVPIRSLEDHTPLPGITVGDIGPKMG---LEHIDNGFLQLNHV 260
Query: 248 RIPRDQMLMRVSQVTREGKYVQSNVPRQLVYGTMVYVRQTIVSDASTAMSRAVCIAARYS 307
R+PR+ ML R ++V +G Y + P+ G +V Q + ++ +A IA RYS
Sbjct: 261 RVPRENMLSRFAEVLPDGTYQRLGTPQSNYLGMLVTRVQLLCKGILPSLQKACIIATRYS 320
Query: 308 AVRRQFGGNNGSLESQVIDYKTQQARLFPLLASAYAFRFVGEWLKWLYTDVMKRLQANDF 367
+R Q E+++++Y+TQQ +L P LA +YAF F L + + DF
Sbjct: 321 VIRHQSRLRPSDPEAKILEYQTQQQKLLPQLAVSYAFHFTATSLSEFFHSSYSAILKRDF 380
Query: 368 STLPEAHACTAGLKSLTTSATSDGIEECRKLCGGHGYLCSSGLPELFAVYVPTCTYEGDN 427
S LPE HA + G+K+ + G E CR+ CGGHGY SGLP L A +CTYEG+N
Sbjct: 381 SLLPELHALSTGMKATFADFCAQGAEICRRACGGHGYSKLSGLPTLVARATASCTYEGEN 440
Query: 428 IVLLLQVARHLMKVISRLGSGKKPVGTTAYMGRVEQLL------EARSDVQKAEDWLNPN 481
VL LQVAR LMK S L + P G T + ++ AR Q A D+ P+
Sbjct: 441 TVLYLQVARFLMK--SYLQAQASP-GATPQKPLPQSVMYIATQRPARCSAQTAADFRCPD 497
Query: 482 TVLRAF---EARAARMSVACAKNLTKFS-NPEEGFQELLADLVDAARAHCQLIVVSKFIE 537
A+ R R + + L K + + + + + AA+AHC I V F E
Sbjct: 498 VYTTAWAYVSTRLIRDAAHRTQTLMKSGVDQHDAWNQTTVIHLQAAKAHCYFITVKNFKE 557
Query: 538 KLQQDIPGKGVKRQLEILCNIYALFHLHKHLGDFLSTGCITPKQGSLANDQLRSLYSQVR 597
+++ ++R L+ LC++YAL + + GDFL G ++ Q +A + L +R
Sbjct: 558 AVEKLDKEPEIQRVLQRLCDLYALHGVLTNSGDFLHDGFLSGAQVDMAREAFLDLLPLIR 617
Query: 598 PNAIALVDAFNYTDHYLSSVLGRYDGNVYPKLYEEAWKDPLNDSVVPDGFQEYIRPML 655
+AI L DAF+++DH L+S LG YDG+VY +L+E A K P N P +++YIRP++
Sbjct: 618 KDAILLTDAFDFSDHCLNSALGCYDGHVYERLFEWAQKYPANTQENP-AYKKYIRPLM 674
>CAOP_CAEEL (P34355) Probable acyl-coenzyme A oxidase, peroxisomal
(EC 1.3.3.6) (Acyl-CoA oxidase) (AOX)
Length = 659
Score = 382 bits (980), Expect = e-105
Identities = 230/657 (35%), Positives = 358/657 (54%), Gaps = 25/657 (3%)
Query: 7 LAFERNKAEFDVDAMKIVWAGSAHAL----EVSDRMSRLVASDPAFRKDHRPMLGRKELF 62
L ER KA FD DA+ V+ G AL E+ D +++ A HR R E
Sbjct: 15 LTDERFKATFDTDALAAVFHGGEDALKRIRELRDEVTKRWHLFDALPGAHRTRAERMEDV 74
Query: 63 KSTLKKAAYAWKRIIELRLTEEEASMLRSFVDEPAFT-DLHWGMFIPAIKGQGTEEQQQK 121
LK + + + ++R + F LH MF+P I+ Q +EQ +
Sbjct: 75 SRKLKNLMESVGEFADFTNNLDMLVIIRDVMGIEGFPLALHNLMFVPTIQNQADDEQTEW 134
Query: 122 WLPLAQRMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHSPTLTSSKWWPGGLGK 181
WL A + +IIG YAQTELGHG+N+ +ETTAT+D T+EF+IH+PT T++KWWPGGLG
Sbjct: 135 WLMDALQGKIIGTYAQTELGHGTNLGAIETTATYDKLTEEFIIHTPTTTATKWWPGGLGT 194
Query: 182 VSTHAVVYARLITDGRDHGVHGFIVQLRSLDDHLPLPGITVGDIGMKFGNGAYNTMDNGV 241
TH V+ A LI D +++G+H F V +R + + + G+ VGDIG K G N +DNG
Sbjct: 195 SCTHVVLVANLIIDTKNYGLHPFFVPIRDRNSYSVMSGVRVGDIGTKMG---VNCVDNGF 251
Query: 242 LRFEHVRIPRDQMLMRVSQVTREGKYVQSNVPRQLVYGTMVYVRQTIVSDASTAMSRAVC 301
L F++ RIPR MLM+ S+V++EG Y + P+ + Y TM+Y+R ++ + ++ A+
Sbjct: 252 LAFDNYRIPRRNMLMKHSKVSKEGLYTAPSHPK-VGYTTMLYMRSEMIYHQAYYLAMAMA 310
Query: 302 IAARYSAVRRQFGGNNGSLESQVIDYKTQQARLFPLLASAYAFRFVGEWLKWLYTDVMKR 361
I+ RYSAVRRQ G+ E Q++DY+TQQ R+FP LA +AF ++ + + +K+
Sbjct: 311 ISIRYSAVRRQGEIKPGTQEVQILDYQTQQYRIFPGLARCFAFNTAAATVRQMTENCIKQ 370
Query: 362 LQANDFSTLPEAHACTAGLKSLTTSATSDGIEECRKLCGGHGYLCSSGLPELFAVYVPTC 421
L + L + HA + GLK++ T S I++ R+ CGGHGY +S LP L+ V C
Sbjct: 371 LSHGNSDVLADLHALSCGLKAVVTHQASQSIDQARQACGGHGYSDASYLPTLYTCSVGAC 430
Query: 422 TYEGDNIVLLLQVARHLMKVISRLGSGKKPVGTTAYMGRVEQLLEARSDVQKAEDWLNPN 481
TYEG+N+V+LLQ++++LMK ++ G++ AY+ + D+ + D
Sbjct: 431 TYEGENMVMLLQLSKYLMKAAAKAEKGEEMAPLVAYL--------VKPDITETNDKF--A 480
Query: 482 TVLRAFEARAARMSVACAKNLTKFSNP----EEGFQELLADLVDAARAHCQLIVVSKFIE 537
+L FE A + + + + + F D AARAH +L + F++
Sbjct: 481 KMLSHFEHIARHRVMHAYRQMIEEEKQGIERDYAFANHSVDWTKAARAHTKLFIARGFVK 540
Query: 538 KLQQDIPGKGVKRQLEILCNIYALFHLHKHLGDFLSTGCITPKQGSLANDQLRSLYSQVR 597
+ Q++ + V L L +Y + L + D + G ++ Q+ + R
Sbjct: 541 SV-QEVSDEAVHDVLTTLAELYLSYELIEMSADLTANGYLSESDVQQIRHQIYDSMRKTR 599
Query: 598 PNAIALVDAFNYTDHYLSSVLGRYDGNVYPKLYEEAWKDPLNDSVVPDGFQEYIRPM 654
NA+++VD+F+ D L SVLGR DG+VY LY+ A PLN+ +P ++Y++PM
Sbjct: 600 RNAVSIVDSFDICDRELRSVLGRRDGHVYENLYKWAQMSPLNERNLPH-VEKYLKPM 655
>CAO4_CANMA (P05335) Acyl-coenzyme A oxidase POX4 (EC 1.3.3.6)
(Acyl-CoA oxidase) (AOX)
Length = 708
Score = 308 bits (788), Expect = 4e-83
Identities = 213/652 (32%), Positives = 344/652 (52%), Gaps = 41/652 (6%)
Query: 10 ERNKAEFDVDAMKIVWAGSAHALEVSDRMSRLVASDPAFRKD--HRPMLGRKELFKSTLK 67
ER ++FD M GS E+ +++ + DP D + + ++ + LK
Sbjct: 22 ERANSKFDPVTMNYFLEGSKERSELMKSLAQQIERDPILFTDGSYYDLTKDQQRELTVLK 81
Query: 68 KAAYAWKRIIELRLTEEEASMLRSFVDEPAFTDL--HWGMFIPAIKGQGTEEQQQKWL-- 123
+ R + T + + VD T + + G+F+ I G GT EQ + W
Sbjct: 82 INRLSRYREGDSVDTFNKRLSIMGVVDPQVATRIGVNLGLFLSCISGNGTAEQFKYWAID 141
Query: 124 -PLAQRMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHSPTLTSSKWWPGGLGKV 182
+ GC+ TELGHGSNV G+ETTATFD +TDEFVI++P + ++KWW GG
Sbjct: 142 KGTHNIQGLYGCFGMTELGHGSNVAGVETTATFDKETDEFVINTPHIGATKWWIGGAAHS 201
Query: 183 STHAVVYARLITDGRDHGVHGFIVQLRSLDDHLPLPGITVGDIGMKFGNGAYNTMDNGVL 242
+TH VYARL+ DG+D+GV F+V LR +H +PG+TVGDIG K G + +DNG +
Sbjct: 202 ATHCSVYARLVVDGKDYGVKTFVVPLRD-SNHDLMPGVTVGDIGAKMGR---DGIDNGWI 257
Query: 243 RFEHVRIPRDQMLMRVSQVTREGKYVQSNVPRQLVYGTMVYVRQTIVSDASTAMSRAVCI 302
+F +VRIPR ML + +V+ EG+ V + QL Y ++ R +V D+ ++R I
Sbjct: 258 QFSNVRIPRFFMLQKFCKVSAEGEVVLPPL-EQLSYSALLGGRVMMVLDSYRMLARVSTI 316
Query: 303 AARYSAVRRQFGGNN------GSLESQVIDYKTQQARLFPLLASAYAFRFVGEWLKWLYT 356
A RY+ RRQF G+N +LE+Q+IDY Q RLFP LA+AY ++
Sbjct: 317 ALRYAIGRRQFKGDNVDQNDPNALETQLIDYPLHQKRLFPYLAAAYVVSTGALKVEHTIQ 376
Query: 357 DVMKRLQA----ND----FSTLPEAHAC---TAGLKSLTTSATSDGIEECRKLCGGHGYL 405
+ L A ND F ++ + + + LK+ TT ++ I++CR+ CGGHGY
Sbjct: 377 STLATLDAAVENNDTTAIFKSIDDMKSLFIDSGSLKATTTWLAAEAIDQCRQACGGHGYS 436
Query: 406 CSSGLPELFAVYVPTCTYEGDNIVLLLQVARHLMK-VISRLGSGKKPVGTTAYMGRVEQL 464
+G + F +V CT+EGDN VL L V + ++K +I +GK G+TA++ +V+
Sbjct: 437 SYNGFAKAFNDWVVQCTWEGDNNVLSLSVGKPIIKQIIGIEDNGKTVRGSTAFLNQVKDF 496
Query: 465 LEARSD---VQKAEDWLNPNTVLRAFEARAARMSVACAKNLTKFSNPEEGFQELLADLVD 521
+ + + D + N V+++ E R++ A ++ K S G A+LV
Sbjct: 497 TGSNASKVVLNNTSDLNDINKVIKSIEVAIIRLAHEAAISVRKESLDFAG-----AELVQ 551
Query: 522 AARAHCQLIVVSKFIEKLQQDIPGKGVKRQLEILCNIY-ALFHLHKHLGDFLSTGCITPK 580
++ ++++F++++ + K + L + +Y A L K G FL+ +P+
Sbjct: 552 ISKLKAHHYLLTEFVKRV-GEFEHKELVPFLNTIGRLYSATVVLDKFAGVFLTFNVASPQ 610
Query: 581 Q-GSLANDQLRSLYSQVRPNAIALVDAFNYTDHYLSSVLGRYDGNVYPKLYE 631
LA+ Q+ L ++VRPN +A D+F +D ++S +G+YDG+VY ++
Sbjct: 611 AITDLASTQIPKLCAEVRPNVVAYTDSFQQSDMVINSAIGKYDGDVYENYFD 662
>CAO2_CANTR (P06598) Acyl-coenzyme A oxidase II (EC 1.3.3.6)
(Acyl-CoA oxidase) (PXP-4) (Peroxisomal fatty acyl-CoA
oxidase)
Length = 708
Score = 293 bits (750), Expect = 1e-78
Identities = 214/658 (32%), Positives = 335/658 (50%), Gaps = 53/658 (8%)
Query: 10 ERNKAEFDVDAMKIVWAGSAHALEVSDRMSRLVASDPAFRKD--HRPMLGRKELFKSTLK 67
ER+ ++++ M GS E+ +++ + DP D + + ++ + +K
Sbjct: 22 ERDSSKWNPQQMNYFLEGSVERSELMKALAQQMERDPILFTDGSYYDLTKDQQRELTAVK 81
Query: 68 KAAYAWKRIIELRLTEEEASMLRSFVDEPAFTDL--HWGMFIPAIKGQGTEEQQQKWL-- 123
A R E T + L D T + + G+F+ I+G GT Q W
Sbjct: 82 INRIARYREQESIDTFNKRLSLIGIFDPQVGTRIGVNLGLFLSCIRGNGTTSQLNYWANE 141
Query: 124 -PLAQRMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHSPTLTSSKWWPGGLGKV 182
A I GC+ TEL HGSNV GLETTATFD ++DEFVI++P + ++KWW GG
Sbjct: 142 KETADVKGIYGCFGMTELAHGSNVAGLETTATFDKESDEFVINTPHIGATKWWIGGAAHS 201
Query: 183 STHAVVYARLITDGRDHGVHGFIVQLRSLDDHLPLPGITVGDIGMKFGNGAYNTMDNGVL 242
+TH VYARLI DG+D+GV F+V LR +H +PG+TVGDIG K G + +DNG +
Sbjct: 202 ATHCSVYARLIVDGQDYGVKTFVVPLRD-SNHDLMPGVTVGDIGPKMGR---DGIDNGWI 257
Query: 243 RFEHVRIPRDQMLMRVSQVTREGKYVQSNVPRQLVYGTMVYVRQTIVSDASTAMSRAVCI 302
+F +VRIPR ML + +V+ EG+ + QL Y ++ R +V D+ ++R I
Sbjct: 258 QFSNVRIPRFFMLQKFCKVSAEGEVTLPPL-EQLSYSALLGGRVMMVLDSYRMLARMSTI 316
Query: 303 AARYSAVRRQFGGNN------GSLESQVIDYKTQQARLFPLLASAYAFRFVGE------- 349
A RY+ RRQF G+N +LE+Q+IDY Q RLFP + V
Sbjct: 317 ALRYAIGRRQFKGDNVDPNDPNALETQLIDYPLHQKRLFPYFVPPMSSPSVPSRLNTPSR 376
Query: 350 --WLKWLYTDVMK----RLQANDFSTLPEAHACTAGLKSLTTSATSDGIEECRKLCGGHG 403
W W T +K RL + + LKS T ++ I++CR+ CGGHG
Sbjct: 377 PPWSNW--TSPLKRTTPRLIFKSIDDMKSLFVDSGSLKSTATWLGAEAIDQCRQACGGHG 434
Query: 404 YLCSSGLPELFAVYVPTCTYEGDNIVLLLQVARHLMK-VISRLGSGKKPVGTTAYMGRVE 462
+ +G + + +V CT+EGDN VL + V + ++K VIS +GK G+TA++ +++
Sbjct: 435 HSSYNGFGKAYNDWVVQCTWEGDNNVLGMSVGKPIVKQVISIEDAGKTVRGSTAFLNQLK 494
Query: 463 QLLEARSD---VQKAEDWLNPNTVLRAFEARAARMSVACAKNLTKFSNPEEGFQELLADL 519
+ + S + D + TV++A E R+S A + K E F + A+L
Sbjct: 495 EYTGSNSSKVVLNTVADLDDIKTVIKAIEVAIIRLSQEAASIVKK-----ESFDYVGAEL 549
Query: 520 VDAARAHCQLIVVSKFIEKLQQDIPGKGVKRQLEILCNIY-ALFHLHKHLGDFL-----S 573
V ++ +++++I ++ K + L L +Y A L + G FL S
Sbjct: 550 VQLSKLKAHHYLLTEYIRRI-DTFDQKELAPYLITLGKLYAATIVLDRFAGVFLTFNVAS 608
Query: 574 TGCITPKQGSLANDQLRSLYSQVRPNAIALVDAFNYTDHYLSSVLGRYDGNVYPKLYE 631
T IT +LA+ Q+ L ++VRPN +A D+F +D ++S +GRYDG++Y ++
Sbjct: 609 TEAIT----ALASVQIPKLCAEVRPNVVAYTDSFQQSDMIVNSAIGRYDGDIYENYFD 662
>CAO1_CANTR (P08790) Acyl-coenzyme A oxidase I (EC 1.3.3.6)
(Acyl-CoA oxidase) (PXP-5)
Length = 661
Score = 288 bits (738), Expect = 2e-77
Identities = 208/642 (32%), Positives = 322/642 (49%), Gaps = 53/642 (8%)
Query: 10 ERNKAEFDVDAMKIVWAGSAHALEVSDRMSRLVASDPAFRKDHRPMLGRKELFKSTLKKA 69
ER +F+ + GS E+ M + DP + D K+ + K
Sbjct: 7 ERELTKFNPKELNYFLEGSQERSEIISNMVEQMQKDPILKVDASYYNLTKDQQREVTAKK 66
Query: 70 AYAWKRIIELRLTEEEASMLR--SFVDEPAFTDL--HWGMFIPAIKGQGTEEQQQKWL-- 123
R E +++A L D FT + + G+F+ ++G GT Q W
Sbjct: 67 IARLSRYFEHEYPDQQAQRLSILGVFDPQVFTRIGVNLGLFVSCVRGNGTNSQFFYWTIN 126
Query: 124 -PLAQRMQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHSPTLTSSKWWPGGLGKV 182
+ + I GC+ TEL HGSNVQG+ETTATFD TDEFVI++P + ++KWW GG
Sbjct: 127 KGIDKLRGIYGCFGMTELAHGSNVQGIETTATFDEDTDEFVINTPHIGATKWWIGGAAHS 186
Query: 183 STHAVVYARLITDGRDHGVHGFIVQLRSLDDHLPLPGITVGDIGMKFGNGAYNTMDNGVL 242
+TH VYARL G+D+GV F+V LR + L PG+TVGDIG K G + +DNG +
Sbjct: 187 ATHCSVYARLKVKGKDYGVKTFVVPLRDSNHDLE-PGVTVGDIGAKMGR---DGIDNGWI 242
Query: 243 RFEHVRIPRDQMLMRVSQVTREGKYVQSNVPRQLVYGTMVYVRQTIVSDASTAMSRAVCI 302
+F +VRIPR ML + +V+R G+ V QL Y ++ R T++ D+ SR + I
Sbjct: 243 QFSNVRIPRFFMLQKYCKVSRSGE-VTMPPSEQLSYSALIGGRVTMMMDSYRMTSRFITI 301
Query: 303 AARYSAVRRQF-GGNNGSLESQVIDYKTQQARLFPLLASAYAFRFVGEWLKWLYTDVMKR 361
A RY+ RRQF + ++E+++IDY Q RLFP LA+AY F +L+ +
Sbjct: 302 ALRYAIHRRQFKKKDTDTIETKLIDYPLHQKRLFPFLAAAYLFSQGALYLEQTMNATNDK 361
Query: 362 L---------QANDFSTLPEAHACTAG--LKSLTTSATSDGIEECRKLCGGHGYLCSSGL 410
L +A D + + A LKS T T++ I+E R+ CGGHGY +G
Sbjct: 362 LDEAVSAGEKEAIDAAIVESKKLFVASGCLKSTCTWLTAEAIDEARQACGGHGYSSYNGF 421
Query: 411 PELFAVYVPTCTYEGDNIVLLLQVARHLMKVISRLGSGKKPVGTTAYMGRVEQLLEARSD 470
+ ++ +V CT+EGDN +L + VA+ +++ + K+P EQ S
Sbjct: 422 GKAYSDWVVQCTWEGDNNILAMNVAKPMVRDLL-----KEP----------EQKGLVLSS 466
Query: 471 VQKAEDWLNPNTVLRAFEARAARMSVACAKNLTKFSNPEEGFQELLADLVDAARAHCQLI 530
V +D P +++AF+ + + A+++ + ++GF LV ++ +
Sbjct: 467 VADLDD---PAKLVKAFDHALSGL----ARDIGAVAE-DKGFDITGPSLVLVSKLNAHRF 518
Query: 531 VVSKFIEKLQQDIPGKGVKRQLEILCNIYALFHLHKHLGDFLSTGCITPK-QGSLANDQL 589
++ F +++ + V R L L YA + L FL G ITP ++++
Sbjct: 519 LIDGFFKRITPE--WSEVLRPLGFL---YADWILTNFGATFLQYGIITPDVSRKISSEHF 573
Query: 590 RSLYSQVRPNAIALVDAFNYTDHYLSSVLGRYDGNVYPKLYE 631
+L ++VRPN + L D FN TD ++ +GRYDGNVY +E
Sbjct: 574 PALCAKVRPNVVGLTDGFNLTDMMTNAAIGRYDGNVYEHYFE 615
>CAO4_CANTR (P11356) Acyl-coenzyme A oxidase PXP-2 (EC 1.3.3.6)
(Acyl-CoA oxidase)
Length = 723
Score = 286 bits (733), Expect = 9e-77
Identities = 191/573 (33%), Positives = 298/573 (51%), Gaps = 31/573 (5%)
Query: 104 GMFIPAIKGQGTEEQQQKWLPLAQR---MQIIGCYAQTELGHGSNVQGLETTATFDPKTD 160
G+F+ ++G GT++Q W + Q+ GC+ TELGHGSNV G ETTATFD KTD
Sbjct: 142 GLFLNCVRGNGTQKQFDFWSNKKEAGIVKQLYGCFGMTELGHGSNVAGCETTATFDEKTD 201
Query: 161 EFVIHSPTLTSSKWWPGGLGKVSTHAVVYARLITDGRDHGVHGFIVQLRSLDDHLPLPGI 220
EF+I +P + ++KWW GG +TH V YARLI D+GV FIV LR H LPGI
Sbjct: 202 EFIIDTPHIGATKWWIGGAAHSATHTVCYARLIVKDVDYGVKTFIVPLRD-SRHSLLPGI 260
Query: 221 TVGDIGMKFGNGAYNTMDNGVLRFEHVRIPRDQMLMRVSQVTREGKYVQSNVPRQLVYGT 280
+GDIG K G +DNG ++F VR+PR ML R +V R+G + QL Y +
Sbjct: 261 AIGDIGAKMGR---QGVDNGWIQFTEVRVPRFFMLQRWCKVDRQGNVTLPPL-EQLSYIS 316
Query: 281 MVYVRQTIVSDASTAMSRAVCIAARYSAVRRQFGGNNGSLESQVIDYKTQQARLFPLLAS 340
++ R + +D+ +R IA RY+ RRQF G E+++IDY Q RL P LA
Sbjct: 317 LLEGRVGMATDSYRIGARYTTIALRYAVGRRQFSKKAGEPETKLIDYTLHQRRLLPYLAL 376
Query: 341 AYAFRFVGEWLKWLYTDVM-----------KRLQANDFSTLPEAHACTAGLKSLTTSATS 389
YA + L+ + +++ K L N + + LKS T +
Sbjct: 377 TYAAAVGTDRLERQHEELLANLDIALAKKDKLLLKNTITGTKSMFVDSGSLKSTLTWLAA 436
Query: 390 DGIEECRKLCGGHGYLCSSGLPELFAVYVPTCTYEGDNIVLLLQVARHLMKVISRLGSGK 449
D I E R+ CGGHGY +G + + +V CT+EGDN VL + + ++K + ++ +GK
Sbjct: 437 DLINETRQACGGHGYSSYNGFGKTYDDWVVQCTWEGDNNVLAMSAGKTIIKTVQQVLNGK 496
Query: 450 K-PVGTTAYMGRVEQLLEARSDVQKAEDWLNP-NTVLRAFEARAARMSVACAKNLTKFSN 507
+ T ++ +L +A+ V + D ++ + VL+A ++ S K+L S
Sbjct: 497 ELKDSTLEFLNAAPELSKAKKAVIRIRDHVDDVDRVLKAIAGLISKFS----KDLIPIS- 551
Query: 508 PEEGFQELLADLVDAARAHCQLIVVSKFIEKLQQDIPGKGVKR-QLEILCNIYALFH-LH 565
+ + + A V ++ C ++ F E+L I K R LE + +Y + + L
Sbjct: 552 -YQSWDSIGAQRVILSKLRCHYYLLETFNERLNDKIKAKSPARPHLENIIKLYYVTNILG 610
Query: 566 KHLGDFLSTGCITPKQGS-LANDQLRSLYSQVRPNAIALVDAFNYTDHYLSSVLGRYDGN 624
+ +FL G I+P+ + + + L + +RP I L D+F D++++S++G+YDGN
Sbjct: 611 PFIDEFLRFGVISPQVAKYITYEYPQKLCANIRPYVIGLTDSFQQPDNFINSLIGKYDGN 670
Query: 625 VYPKLYEEAWKDPLNDSVVPDGFQEYIRPMLKQ 657
+Y Y E+ KD + S + E + ML +
Sbjct: 671 IYTN-YLESVKDVNDPSNYKAPYSEALEAMLNR 702
>CAO3_HUMAN (O15254) Acyl-coenzyme A oxidase 3, peroxisomal (EC
1.3.3.6) (Pristanoyl-CoA oxidase)
Length = 700
Score = 285 bits (729), Expect = 3e-76
Identities = 196/563 (34%), Positives = 295/563 (51%), Gaps = 29/563 (5%)
Query: 101 LHWGMFIPAIKGQGTEEQQQKWLPLAQRMQIIGCYAQTELGHGSNVQGLETTATFDPKTD 160
LH +F A+ G+E + ++ RM+I GC+A TEL HGSN + + TTA +DP T+
Sbjct: 123 LHSLVFGSAVYSSGSE-RHLTYIQKIFRMEIFGCFALTELSHGSNTKAIRTTAHYDPATE 181
Query: 161 EFVIHSPTLTSSKWWPGGLGKVSTHAVVYARLITDG-RDHGVHGFIVQLRSLDDHLPLPG 219
EF+IHSP ++K+W G +GK +THAVV+A+L G + HG+H FIVQ+R LP+PG
Sbjct: 182 EFIIHSPDFEAAKFWVGNMGKTATHAVVFAKLCVPGDQCHGLHPFIVQIRDPKTLLPMPG 241
Query: 220 ITVGDIGMKFGNGAYNTMDNGVLRFEHVRIPRDQMLMRVSQVTREGKYVQ--SNVPRQL- 276
+ VGDIG K G N +DNG F VR+PR +L R+ VT EG YV +V ++
Sbjct: 242 VMVGDIGKKLGQ---NGLDNGFAMFHKVRVPRQSLLNRMGDVTPEGTYVSPFKDVRQRFG 298
Query: 277 -VYGTMVYVRQTIVSDASTAMSRAVCIAARYSAVRRQFGGNNGSLESQVIDYKTQQARLF 335
G++ R +IVS A + AV IA R+SA RRQFG E V++Y QQ RL
Sbjct: 299 ASLGSLSSGRVSIVSLAILNLKLAVAIALRFSATRRQFGPTEEE-EIPVLEYPMQQWRLL 357
Query: 336 PLLASAYAFRFVGEWLKWLYTDVMKRLQANDFSTLP-----EAHACTAGLKSLTTSATSD 390
P LA+ Y + L ++ + L + D S E HA + K L + T
Sbjct: 358 PYLAAVYGLDHFSKSLFLDLVELQRGLASGDRSARQAELGREIHALASASKPLASWTTQQ 417
Query: 391 GIEECRKLCGGHGYLCSSGLPELFAVYVPTCTYEGDNIVLLLQVARHLMKVIS-RLGSG- 448
GI+ECR+ CGGHGYL + L L P CTYEGDN +LL Q + +L+ +++ ++ G
Sbjct: 418 GIQECREACGGHGYLAMNRLGVLRDDNDPNCTYEGDNNILLQQTSNYLLGLLAHQVHDGA 477
Query: 449 --KKPVGTTAYMGRVEQLLEARSDVQKAEDWLNPNTVLRAFEARAARMSVACAKNLTK-- 504
+ P+ + ++ +L+ + +V D L+ L A++ + + L +
Sbjct: 478 CFRSPLKSVDFLDAYPGILDQKFEVSSVADCLDSAVALAAYKWLVCYLLRETYQKLNQEK 537
Query: 505 ---FSNPEEGFQELLADLVDAARAHCQLIVVSKFIEKLQQDIPGKGVKRQLEILCNIYAL 561
S+ E + ++ A A +L VV +F E + Q ++ L L +YAL
Sbjct: 538 RSGSSDFEARNKCQVSHGRPLALAFVELTVVQRFHEHVHQPSVPPSLRAVLGRLSALYAL 597
Query: 562 FHLHKHLGDFLSTGCITPKQ-GSLANDQLRSLYSQVRPNAIALVDAFNYTDHYLSSVLGR 620
+ L +H G + +Q G + + +L SQ++ +A+ALVD D L S +GR
Sbjct: 598 WSLKRHAALLYRGGYFSGEQAGEVLESAVLALCSQLKDDAVALVDVIAPPDFVLDSPIGR 657
Query: 621 YDGNVYPKLYEEAWKDPLNDSVV 643
DG +LY+ W L +S V
Sbjct: 658 ADG----ELYKNLWGAVLQESKV 676
>CAO3_RAT (Q63448) Acyl-coenzyme A oxidase 3, peroxisomal (EC
1.3.3.6) (Pristanoyl-CoA oxidase)
Length = 700
Score = 282 bits (721), Expect = 2e-75
Identities = 193/555 (34%), Positives = 283/555 (50%), Gaps = 35/555 (6%)
Query: 101 LHWGMFIPAIKGQGTEEQQQKWLPLAQRMQIIGCYAQTELGHGSNVQGLETTATFDPKTD 160
LH +F I G G+E K+L ++I GC+A TEL HGSN + + TTA +DP T
Sbjct: 123 LHMLVFGSTIIGSGSEHHF-KYLEKIYNLEIFGCFALTELSHGSNTKAMRTTAHYDPATQ 181
Query: 161 EFVIHSPTLTSSKWWPGGLGKVSTHAVVYARLIT-DGRDHGVHGFIVQLRSLDDHLPLPG 219
EF++HSP ++K+W G LGK +THAVV+A+L T DG+ G+H F+VQ+R LP+PG
Sbjct: 182 EFILHSPDFEAAKFWVGNLGKTATHAVVFAQLYTPDGQCRGLHSFLVQIRDPKTLLPMPG 241
Query: 220 ITVGDIGMKFGNGAYNTMDNGVLRFEHVRIPRDQMLMRVSQVTREGKY------VQSNVP 273
+ VGD+G K G N +DNG F VRIPR +L R VT EG Y V+ +
Sbjct: 242 VMVGDMGKKLGQ---NGLDNGFAMFHKVRIPRQNLLDRTGNVTSEGHYHTPFKDVRQRLG 298
Query: 274 RQLVYGTMVYVRQTIVSDASTAMSRAVCIAARYSAVRRQFGGNNGSLESQVIDYKTQQAR 333
L G++ R +I+S + + AV IA R+SA RRQFG + E V++Y QQ R
Sbjct: 299 ASL--GSLSSGRISIISISVVNLKLAVIIAIRFSATRRQFGPTDKE-EIPVLEYPLQQWR 355
Query: 334 LFPLLASAYAFRFVGEWLKWLYTDVMKRLQANDFSTL--------PEAHACTAGLKSLTT 385
L P LA+AYA + + K ++ D+++ +A T E HA + K L +
Sbjct: 356 LLPYLAAAYA---LDHFSKTIFLDLIELQRAGKVGTTVTGRQSSGREIHALASAGKPLAS 412
Query: 386 SATSDGIEECRKLCGGHGYLCSSGLPELFAVYVPTCTYEGDNIVLLLQVARHLMKVISR- 444
GI+ECR++ GGHGYL + EL P CTYEGDN VLL Q + +L+ ++
Sbjct: 413 WTAQRGIQECREVVGGHGYLAMNRFGELRNDNDPNCTYEGDNNVLLQQTSNYLLSLLEHP 472
Query: 445 LGSG---KKPVGTTAYMGRVEQLLEARSDVQKAEDWLNPNTVLRAFEARAARM-----SV 496
L G P+ T ++ +L + DWL+ L A+ +
Sbjct: 473 LQDGAHFTSPLKTVNFLEAYPGILGQKFMASSKADWLDSEAPLAAYRWLVCYLLRESHQR 532
Query: 497 ACAKNLTKFSNPEEGFQELLADLVDAARAHCQLIVVSKFIEKLQQDIPGKGVKRQLEILC 556
C + ++ S+ E + A A +L V+ +F E ++ L L
Sbjct: 533 YCQEKKSRGSDFEARNNSQVYGCRPLALAFMELTVMQRFHEHTHSSSVPPSLRTVLGRLS 592
Query: 557 NIYALFHLHKHLGDFLSTGCITPKQ-GSLANDQLRSLYSQVRPNAIALVDAFNYTDHYLS 615
+Y L+ L +H G I+ +Q G D + L Q++ +A+ALVDA +D L
Sbjct: 593 MLYGLWCLSQHTALLYRGGYISGEQTGKAMEDAILMLCVQLKDDAVALVDAIAPSDFVLG 652
Query: 616 SVLGRYDGNVYPKLY 630
S +GR DG +Y L+
Sbjct: 653 SPIGRADGELYKNLW 667
>CAO2_CANMA (Q00468) Acyl-coenzyme A oxidase POX2 (EC 1.3.3.6)
(Acyl-CoA oxidase) (AOX)
Length = 724
Score = 263 bits (673), Expect = 8e-70
Identities = 192/642 (29%), Positives = 311/642 (47%), Gaps = 32/642 (4%)
Query: 7 LAFERNKAEFDVDAMKIVWAGSAHALEVSDRMSRLVASDPAFRKDHRPMLGRKELFKSTL 66
+A ER++ ++D+ M G E R+ + + DP + K + ++
Sbjct: 42 VAEERSRTDWDLKEMHEFLEGDEAKSEEILRLYQSIERDPILQTRPEQFDYTKNEERESV 101
Query: 67 KKAAYAWKRIIELRLTEEEASMLRSF-VDEPAFTD---LHWGMFIPAIKGQGTEEQQQKW 122
+ +E E+ L+ V++P+ ++ G+F+ I+G GT++Q W
Sbjct: 102 ALRINQMSKYLETEPYEKFRRRLQLMTVNDPSLGIRMLVNIGLFLNCIRGNGTQKQYDFW 161
Query: 123 LPLAQR---MQIIGCYAQTELGHGSNVQGLETTATFDPKTDEFVIHSPTLTSSKWWPGGL 179
+ Q++ + ELGHG NV G E ATFD KTD+F+I +P + ++KWW GG
Sbjct: 162 AKTKEAGKVKQLLRLFRYDELGHGFNVAGCEIFATFDEKTDQFIIDTPHIGATKWWIGGA 221
Query: 180 GKVSTHAVVYARLITDGRDHGVHGFIVQLRSLDDHLPLPGITVGDIGMKFGNGAYNTMDN 239
+TH V YARLI D+GV F+V LR H LPG+ +GDIG K G +DN
Sbjct: 222 AHSATHTVCYARLIVKDIDYGVKTFVVPLRD-STHNLLPGVAIGDIGPKLGR---QGVDN 277
Query: 240 GVLRFEHVRIPRDQMLMRVSQVTREGKYVQSNVPRQLVYGTMVYVRQTIVSDASTAMSRA 299
G ++F VRIPR ML R +V R+G + QL Y +++ R + +D+ +R
Sbjct: 278 GWIQFTEVRIPRFFMLQRWCKVDRQGNVTLPPL-EQLSYISLLEGRVGMATDSYRIGARY 336
Query: 300 VCIAARYSAVRRQFGGNNGSLESQVIDYKTQQARLFPLLASAYAFRFVGEWLKWLYTDVM 359
IA RY+ RRQF +G E+++IDY Q RL P LA Y + L+ + ++
Sbjct: 337 TTIALRYAVARRQFSKGDGQPETKLIDYTLHQRRLLPYLALTYLAALGTDKLERQHDQLL 396
Query: 360 KRLQ-----------ANDFSTLPEAHACTAGLKSLTTSATSDGIEECRKLCGGHGYLCSS 408
K L N + + LKS T SD I E R+ CGGHGY +
Sbjct: 397 KNLDKALATNNKLLLKNTIQSTKSMFVDSGSLKSTLTWLASDLINEARQSCGGHGYSAYN 456
Query: 409 GLPELFAVYVPTCTYEGDNIVLLLQVARHLMKVISRLGSGKK-PVGTTAYMGRVEQLLEA 467
G + + + CT+EGDN VL + + ++K + ++ +GK+ T ++ L A
Sbjct: 457 GFGKTYGDWAVQCTWEGDNNVLGMSAGKTIIKTVQQVLNGKQLKDSTLEFLNDAPALSSA 516
Query: 468 RSDVQKAEDWLNPNTVLRAFEARAARMSVACAKNLTKFSNPEEGFQELLADLVDAARAHC 527
+ V + + ++ R +A A +S AK+L S + + + V ++ C
Sbjct: 517 KKAVIRIKSHVDDTD--RVLKAIAGLIS-KYAKDLIPVS--YQSWDSIGPQRVVLSKFRC 571
Query: 528 QLIVVSKFIEKLQQDIPGKGVKR-QLEILCNIYALFH-LHKHLGDFLSTGCITPKQGS-L 584
++ F E+L I K R LE + +Y + + L + +FL G I+P +
Sbjct: 572 HYYLLETFNERLNDRIKAKSPARPHLENIIKLYYVTNVLGPFIDEFLRFGVISPSVAKYI 631
Query: 585 ANDQLRSLYSQVRPNAIALVDAFNYTDHYLSSVLGRYDGNVY 626
+ + L + +RP I L D+F D++++S++GRYDGNVY
Sbjct: 632 TTEYPQKLCAAIRPYVIGLTDSFQQPDNFINSLIGRYDGNVY 673
>CAO3_MOUSE (Q9EPL9) Acyl-coenzyme A oxidase 3, peroxisomal (EC
1.3.3.6) (Pristanoyl-CoA oxidase)
Length = 700
Score = 261 bits (667), Expect = 4e-69
Identities = 179/550 (32%), Positives = 279/550 (50%), Gaps = 25/550 (4%)
Query: 101 LHWGMFIPAIKGQGTEEQQQKWLPLAQRMQIIGCYAQTELGHGSNVQGLETTATFDPKTD 160
LH +F + G+E+ K+L ++I GC+A TEL HGSN + + TTA ++ T
Sbjct: 123 LHMLVFGTTVFVSGSEKHF-KYLEKIYSLEIFGCFALTELSHGSNTKAMRTTAHYESDTQ 181
Query: 161 EFVIHSPTLTSSKWWPGGLGKVSTHAVVYARL-ITDGRDHGVHGFIVQLRSLDDHLPLPG 219
EF++HSP ++K+W G LGK +THAVV+A+L + DG+ HG+H F+VQ+R LP+ G
Sbjct: 182 EFILHSPDFEAAKFWVGNLGKTATHAVVFAQLYMPDGQCHGLHSFLVQIRDTKTLLPMTG 241
Query: 220 ITVGDIGMKFGNGAYNTMDNGVLRFEHVRIPRDQMLMRVSQVTREGKYVQ--SNVPRQL- 276
+ VGDIG K G N +DNG F VRIPR +L R +T EG Y +V ++L
Sbjct: 242 VMVGDIGKKLGQ---NGLDNGFAMFNKVRIPRQNLLDRTGNITSEGTYNSPFKDVRQRLG 298
Query: 277 -VYGTMVYVRQTIVSDASTAMSRAVCIAARYSAVRRQFGGNNGSLESQVIDYKTQQARLF 335
G++ R +I+S + + AV IA R+SA R QFG + E V++Y QQ R+
Sbjct: 299 ASLGSLSSGRISIISMSVVNLKLAVSIAIRFSATRCQFGPTDKE-EIPVLEYPLQQWRIL 357
Query: 336 PLLASAYAFRFVGEWLKWLYTDVMKRLQANDFSTLP-----EAHACTAGLKSLTTSATSD 390
P LA+A+A + + +V D S E HA + L +
Sbjct: 358 PYLAAAHALDHFSKTIFMDLIEVQSARLRGDHSDQQAELGREIHALASAGNRLASWTAQR 417
Query: 391 GIEECRKLCGGHGYLCSSGLPELFAVYVPTCTYEGDNIVLLLQVARHLMKVIS-RLGSG- 448
GI+ECR+ CGGHGYL + +L P CTYEGDN VLL Q + +L+ ++ L G
Sbjct: 418 GIQECREACGGHGYLAMNRFGDLRNDNDPNCTYEGDNNVLLQQTSNYLLSLLEPPLQDGA 477
Query: 449 --KKPVGTTAYMGRVEQLLEARSDVQKAEDWLNPNTVLRAFEARAARMSVA-----CAKN 501
P+ T ++ +L + DW++ L A+ + C +
Sbjct: 478 HFTSPLKTVDFLEAYPGILGQKFLGSSKADWMDSAAPLAAYRWLVCYLLQESHRRYCQEK 537
Query: 502 LTKFSNPEEGFQELLADLVDAARAHCQLIVVSKFIEKLQQDIPGKGVKRQLEILCNIYAL 561
++ S+ E + + A A +L V+ +F E + ++ L L ++Y L
Sbjct: 538 KSRGSDFEARNNSQVYGVRPLALAFMELTVMQRFHEHIHSSGLSPSLRTVLGRLSSVYGL 597
Query: 562 FHLHKHLGDFLSTGCITPKQ-GSLANDQLRSLYSQVRPNAIALVDAFNYTDHYLSSVLGR 620
+ L +H+ G I+ +Q G D + +L Q++ +A+ALVD +D L+S + +
Sbjct: 598 WCLSQHMALSYRGGYISGEQTGRAMEDAILTLCEQLKDDAVALVDVIAPSDFVLNSPIAK 657
Query: 621 YDGNVYPKLY 630
DG +Y L+
Sbjct: 658 ADGELYKNLW 667
>CAO_YEAST (P13711) Acyl-coenzyme A oxidase (EC 1.3.3.6) (Acyl-CoA
oxidase)
Length = 748
Score = 250 bits (638), Expect = 1e-65
Identities = 207/657 (31%), Positives = 304/657 (45%), Gaps = 95/657 (14%)
Query: 35 SDRMSRLVASDPAFRKDHRPMLGRKELFKSTLKKAAYAWKRIIELRLTEEEASMLRSFVD 94
+D M L A+DP D L K+LF I + RL+ L + +D
Sbjct: 104 TDLMKELQANDP----DKASPLTNKDLF-------------IFDKRLS------LVANID 140
Query: 95 EPAFT--DLHWGMFIPAIKGQGTEEQQQKWLPL--AQRMQ-IIGCYAQTELGHGSNVQGL 149
T +H G+F IKG GT+EQ + WL A M+ I GC+A TELGHGSNV L
Sbjct: 141 PQLGTRVGVHLGLFGNCIKGNGTDEQIRYWLQERGATLMKGIYGCFAMTELGHGSNVAQL 200
Query: 150 ETTATFDPKTDEFVIHSPTLTSSKWWPGGLGKVSTHAVVYARLITDGRDHGVHGFIVQLR 209
+T A +D + D FVI +P LT++KWW GG +THA VYARLI +G+D+GV F+V LR
Sbjct: 201 QTRAVYDKQNDTFVIDTPDLTATKWWIGGAAHSATHAAVYARLIVEGKDYGVKTFVVPLR 260
Query: 210 SLDDHLPLPGITVGDIGMKFGNGAYNTMDNGVLRFEHVRIPRDQMLMRVSQVTR--EGKY 267
L G+++GDIG K G + +DNG ++F +V IPR+ ML R ++V R +G
Sbjct: 261 DPSTFQLLAGVSIGDIGAKMGR---DGIDNGWIQFRNVVIPREFMLSRFTKVVRSPDGSV 317
Query: 268 VQSNVPR--QLV-YGTMVYVRQTIVSDASTAMSRAVCIAARYSAVRRQFGGNNGSLESQV 324
P+ Q+ Y ++ R +V D+ S+ IA RY+ R+QF G E+Q+
Sbjct: 318 TVKTEPQLDQISGYSALLSGRVNMVMDSFRFGSKFATIAVRYAVGRQQFAPRKGLSETQL 377
Query: 325 IDYKTQQARLFPLLASAYAFRFVGEWLKWLYTDVMKRLQANDFSTLPEAHAC-------- 376
IDY Q R+ P L Y L + V +L N +STL E +
Sbjct: 378 IDYPLHQYRVLPQLCVPY-----------LVSPVAFKLMDNYYSTLDELYNASSSAYKAA 426
Query: 377 --------------TAGLKSLTTSATSDGIEECRKLCGGHGYLCSSGLPELFAVYVPTCT 422
+A LK+ T + I+E R+ CGGHGY +G + + +V CT
Sbjct: 427 LVTVSKKLKNLFIDSASLKATNTWLIATLIDELRQTCGGHGYSQYNGFGKGYDDWVVQCT 486
Query: 423 YEGDNIVLLLQVARHLMKVISRLGSGKKPVGTTAYMGRVEQLLEARSDVQKAEDWLNP-- 480
+EGDN VL L A+ ++K +A GR + L+ S ++
Sbjct: 487 WEGDNNVLSLTSAKSILKKFI----------DSATKGRFDNTLDVDSFSYLKPQYIGSVV 536
Query: 481 ----NTVLRAFEARAARMSVACAKNLTKFSNPEE---GFQELLADLVDAARAHCQLIVVS 533
+ L+ S+ K L E + LV ++ H ++
Sbjct: 537 SGEIKSGLKELGDYTEIWSITLIKLLAHIGTLVEKSRSIDSVSKLLVLVSKFHALRCMLK 596
Query: 534 KFIEKLQQDIPGKGVKRQLEILCNIYALFHLH---KHLGDFLSTGCITPKQ-GSLANDQL 589
+ +KL + E + N+Y LF L+ KH G+F TP Q + QL
Sbjct: 597 TYYDKLNSRDSHISDEITKESMWNVYKLFSLYFIDKHSGEFQQFKIFTPDQISKVVQPQL 656
Query: 590 RSLYSQVRPNAIALVDAFNYTDHYLSSVLGRYDGNVYPKLYEEAWKDPLNDSVVPDG 646
+L VR + I L D+F D L+S +G +DG++Y + E + N+ V DG
Sbjct: 657 LALLPIVRKDCIGLTDSFELPDAMLNSPIGYFDGDIYHNYFNEVCR---NNPVEADG 710
>CAO3_CANTR (P11355) Acyl-coenzyme A oxidase POX4-2 (EC 1.3.3.6)
(Acyl-CoA oxidase) (Fragment)
Length = 502
Score = 215 bits (548), Expect = 3e-55
Identities = 156/471 (33%), Positives = 252/471 (53%), Gaps = 42/471 (8%)
Query: 188 VYARLITDGRDHGVHGFIVQLRSLDDHLPLPGITVGDIGMKFGNGAYNTMDNGVLRFEHV 247
VYARLI DG D+GV F+V LR +H +PG+TVGDIG K G +DNG ++F +V
Sbjct: 1 VYARLIVDGEDYGVKTFVVPLRD-SNHDLMPGVTVGDIGAKMGRDG---IDNGWIQFSNV 56
Query: 248 RIPRDQMLMRVSQVTREGKYVQSNVPRQLVYGTMVYVRQTIVSDASTAMSRAVCIAARYS 307
RIPR ML + +V+ EG+ + QL Y ++ R +V D+ ++R IA RY+
Sbjct: 57 RIPRFFMLQKFCKVSAEGEVTLPPL-EQLSYSALLGGRVMMVLDSYRMLARMSTIALRYA 115
Query: 308 AVRRQFGGNN------GSLESQVIDYKTQQARLFPLLASAYAFRF----VGEWLKWLYTD 357
RRQF G+N +LE+Q+IDY Q RLFP LA+AY V ++ +
Sbjct: 116 IGRRQFKGDNVDPNDPNALETQLIDYPLHQKRLFPYLAAAYVVSAGALKVEHTIETTLAE 175
Query: 358 VMKRLQAND----FSTLPEAHAC---TAGLKSLTTSATSDGIEECRKLCGGHGYLCSSGL 410
+ ++ ND F ++ + + + LKS T ++ I++CR+ CGGHG+ +G
Sbjct: 176 LDAAVEKNDTKAIFKSIDDMKSLFVDSGSLKSTATWLGAEAIDQCRQACGGHGHSSYNGF 235
Query: 411 PELFAVYVPTCTYEGDNIVLLLQVARHLMK-VISRLGSGKKPVGTTAYMGRVEQLLEARS 469
+ + +V CT+EGDN VL + V + ++K VIS +GK G+TA++ ++++ + S
Sbjct: 236 GKAYNDWVVQCTWEGDNNVLGMSVGKPIVKQVISIEDAGKTVRGSTAFLNQLKEYTGSNS 295
Query: 470 D---VQKAEDWLNPNTVLRAFEARAARMSVACAKNLTKFSNPEEGFQELLADLVDAARAH 526
+ D + TV++A E R+S A + K E F + A+LV ++
Sbjct: 296 SKVVLNTVADLDDIKTVIKAIEVAIIRLSQEAASIVKK-----ESFDYVGAELVQLSKLK 350
Query: 527 CQLIVVSKFIEKLQQDIPGKGVKRQLEILCNIY-ALFHLHKHLGDFL-----STGCITPK 580
+++++I ++ K + L L +Y A L + G FL ST IT
Sbjct: 351 AHHYLLTEYIRRI-DTFDQKELAPYLITLGKLYAATIVLDRFAGVFLTFNVASTEAIT-- 407
Query: 581 QGSLANDQLRSLYSQVRPNAIALVDAFNYTDHYLSSVLGRYDGNVYPKLYE 631
+LA+ Q+ L ++VRPN +A D+F +D ++S +GRYDG++Y ++
Sbjct: 408 --ALASVQIPKLCAEVRPNVVAYTDSFQQSDMIVNSAIGRYDGDIYENYFD 456
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.321 0.136 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,933,402
Number of Sequences: 164201
Number of extensions: 3235566
Number of successful extensions: 7327
Number of sequences better than 10.0: 72
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 7162
Number of HSP's gapped (non-prelim): 74
length of query: 664
length of database: 59,974,054
effective HSP length: 117
effective length of query: 547
effective length of database: 40,762,537
effective search space: 22297107739
effective search space used: 22297107739
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)
Medicago: description of AC149079.11