BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC148995.13 - phase: 0 
         (160 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

SPL1_HUMAN (Q14515) SPARC-like protein 1 precursor (High endothe...    37  0.019
LCP2_HUMAN (Q13094) Lymphocyte cytosolic protein 2 (SH2 domain-c...    34  0.12
UVE1_NEUCR (Q01408) UV-damage endonuclease (EC 3.-.-.-) (UV-endo...    33  0.21
EF2K_RAT (P70531) Elongation factor 2 kinase (EC 2.7.1.-) (eEF-2...    32  0.61
EF2K_MOUSE (O08796) Elongation factor 2 kinase (EC 2.7.1.-) (eEF...    32  0.61
CYSP_PLAFA (P25805) Trophozoite cysteine proteinase precursor (E...    31  1.0
TP2B_HUMAN (Q02880) DNA topoisomerase II, beta isozyme (EC 5.99....    30  1.8
T2EA_SCHPO (Q9P3W1) Transcription initiation factor IIE, alpha s...    30  1.8
YGX7_YEAST (P53076) Hypothetical 108.2 kDa protein in SAP4-OST5 ...    30  2.3
CHD1_MOUSE (P40201) Chromodomain-helicase-DNA-binding protein 1 ...    30  2.3
TP2B_CRILO (Q64399) DNA topoisomerase II, beta isozyme (EC 5.99....    30  3.0
TOP1_YEAST (P04786) DNA topoisomerase I (EC 5.99.1.2)                  30  3.0
DEK_HUMAN (P35659) DEK protein                                         30  3.0
CHD1_HUMAN (O14646) Chromodomain-helicase-DNA-binding protein 1 ...    30  3.0
RA54_SCHPO (P41410) DNA repair protein rhp54 (EC 3.6.1.-) (RAD54...    29  4.0
MSH3_YEAST (P25336) MUTS protein homolog 3 (Mismatch binding pro...    29  4.0
FRPC_NEIMC (P55127) Iron-regulated protein frpC                        29  4.0
FRPC_NEIMB (Q9JYV5) Iron-regulated protein frpC                        29  4.0
ATRX_MOUSE (Q61687) Transcriptional regulator ATRX (X-linked nuc...    29  4.0
NP14_RAT (P41777) Nucleolar phosphoprotein p130 (Nucleolar 130 k...    29  5.2

>SPL1_HUMAN (Q14515) SPARC-like protein 1 precursor (High
           endothelial venule protein) (Hevin) (MAST 9)
          Length = 664

 Score = 37.0 bits (84), Expect = 0.019
 Identities = 27/119 (22%), Positives = 45/119 (37%), Gaps = 10/119 (8%)

Query: 22  NQKSSQGKELEFDEADVWNMSYSNSNTNIEPKKGVPGLKRVSRKMEANNKVNPLASSSLP 81
           NQ+       E +E +  N++     T  + ++G  GL+ +S   E   K     S +L 
Sbjct: 265 NQEQEDNSNAEMEEENASNVNKHIQETEWQSQEGKTGLEAISNHKETEEKT---VSEALL 321

Query: 82  MNIPDWSKILKEEYKKKKESSDDEDEGDYDGVVQ-------LPPHEYLARTRGASLSVH 133
           M   D        +    +  DD D+G  DG          +P   +L   R  S++ H
Sbjct: 322 MEPTDDGNTTPRNHGVDDDGDDDGDDGGTDGPRHSASDDYFIPSQAFLEAERAQSIAYH 380


>LCP2_HUMAN (Q13094) Lymphocyte cytosolic protein 2 (SH2
           domain-containing leucocyte protein of 76 kDa) (SLP-76
           tyrosine phosphoprotein) (SLP76)
          Length = 533

 Score = 34.3 bits (77), Expect = 0.12
 Identities = 24/108 (22%), Positives = 46/108 (42%), Gaps = 14/108 (12%)

Query: 16  FPETNFNQKSSQGKELEFDEADVWNMSYSNSNTNIEPKKGVPGLKRVSRKMEANNKVN-- 73
           F + N+       K+   D A   N++   ++    PK  VP L ++S+++  N +    
Sbjct: 24  FKKLNYKDCEKAVKKYHIDGARFLNLT--ENDIQKFPKLRVPILSKLSQEINKNEERRSI 81

Query: 74  ----------PLASSSLPMNIPDWSKILKEEYKKKKESSDDEDEGDYD 111
                     P  + S   +   WS   +++Y+   +  D ED+GDY+
Sbjct: 82  FTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYE 129


>UVE1_NEUCR (Q01408) UV-damage endonuclease (EC 3.-.-.-)
           (UV-endonuclease UVE-1)
          Length = 656

 Score = 33.5 bits (75), Expect = 0.21
 Identities = 14/32 (43%), Positives = 19/32 (58%)

Query: 81  PMNIPDWSKILKEEYKKKKESSDDEDEGDYDG 112
           P+   +W K  K E KK K   + EDEG++DG
Sbjct: 625 PLGCEEWLKPKKREVKKGKVPEEVEDEGEFDG 656


>EF2K_RAT (P70531) Elongation factor 2 kinase (EC 2.7.1.-) (eEF-2
           kinase) (eEF-2K) (Calcium/calmodulin-dependent
           eukaryotic elongation factor-2 kinase)
          Length = 724

 Score = 32.0 bits (71), Expect = 0.61
 Identities = 16/44 (36%), Positives = 24/44 (54%), Gaps = 1/44 (2%)

Query: 81  PMNIPDWSKILKEEYKKKKESSDDEDEGDYDGVVQLPPHEYLAR 124
           P    DWS+ L   Y    E++D ++ G+YDG+   P +  LAR
Sbjct: 627 PDRCQDWSEAL-HWYNTALETTDCDEGGEYDGIQDEPQYALLAR 669


>EF2K_MOUSE (O08796) Elongation factor 2 kinase (EC 2.7.1.-) (eEF-2
           kinase) (eEF-2K) (Calcium/calmodulin-dependent
           eukaryotic elongation factor-2 kinase)
          Length = 724

 Score = 32.0 bits (71), Expect = 0.61
 Identities = 16/44 (36%), Positives = 24/44 (54%), Gaps = 1/44 (2%)

Query: 81  PMNIPDWSKILKEEYKKKKESSDDEDEGDYDGVVQLPPHEYLAR 124
           P    DWS+ L   Y    E++D ++ G+YDG+   P +  LAR
Sbjct: 627 PDRCQDWSEAL-HWYNTALETTDCDEGGEYDGIQDEPQYALLAR 669


>CYSP_PLAFA (P25805) Trophozoite cysteine proteinase precursor (EC
           3.4.22.-) (TCP)
          Length = 569

 Score = 31.2 bits (69), Expect = 1.0
 Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 5/58 (8%)

Query: 58  GLKRVSRKMEANNKVNPLASSSLPMNIPDWSKILKEEYKKKK-----ESSDDEDEGDY 110
           G+   + K  A+N  N     SL     +  ++L E+YKK+K     ESS++EDE  Y
Sbjct: 52  GILYFTNKSSAHNNNNNKNEHSLKKEEIELLRVLLEKYKKQKDGILNESSNEEDEEKY 109


>TP2B_HUMAN (Q02880) DNA topoisomerase II, beta isozyme (EC 5.99.1.3)
          Length = 1626

 Score = 30.4 bits (67), Expect = 1.8
 Identities = 30/113 (26%), Positives = 49/113 (42%), Gaps = 16/113 (14%)

Query: 15   IFPETNFNQKSSQGKEL----EFDEADVWNMSYSNSNTNIEP------KKG------VPG 58
            +F   +++QKS          E D A V++ S+    T+  P      KKG      VP 
Sbjct: 1447 LFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTVPK 1506

Query: 59   LKRVSRKMEANNKVNPLASSSLPMNIPDWSKILKEEYKKKKESSDDEDEGDYD 111
             KR  ++ +    VN  + S   +     +   K    KK+++S  E+EGDY+
Sbjct: 1507 PKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYN 1559


>T2EA_SCHPO (Q9P3W1) Transcription initiation factor IIE, alpha
           subunit (TFIIE-alpha)
          Length = 448

 Score = 30.4 bits (67), Expect = 1.8
 Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 17/75 (22%)

Query: 45  NSNTNIEPKKGVPGLKRVSRKMEANNKVNPLASSSLPMNIPDWSKILKEEYKK------K 98
           NS+++I+ K+        ++ +E NN + P+ S++    I D    ++E  K        
Sbjct: 385 NSDSDIQNKR--------TKSIEENNSLPPIVSTN---GITDGDTEMQESKKNVIINGFN 433

Query: 99  KESSDDEDEGDYDGV 113
           ++  DDEDE D++ V
Sbjct: 434 EDDEDDEDEADFEDV 448


>YGX7_YEAST (P53076) Hypothetical 108.2 kDa protein in SAP4-OST5
           intergenic region
          Length = 958

 Score = 30.0 bits (66), Expect = 2.3
 Identities = 27/123 (21%), Positives = 49/123 (38%), Gaps = 14/123 (11%)

Query: 23  QKSSQGKELEFDEADVWNMSYSNSNTNIEPKKGVPGLKRVSRKMEANNKVNPLASSSLPM 82
           Q+S     +E +  ++W+ S  NS     P    P     S ++ + N  N   ++++  
Sbjct: 244 QRSRSAINIETESRNLWDTSDKNSGLQYYPPDQSPSSSFSSPRVSSGNDKNDNEATNVLS 303

Query: 83  N---------IPDWSKILKEEYKKKKESSDDED-EGDYDGVVQLPP----HEYLARTRGA 128
           N         IPD  KIL      + ++  +   +   DG+  L P    H Y+   R +
Sbjct: 304 NSGSKKKNSMIPDIYKILGYFLPSRWQAQPNNSLQLSQDGITHLQPNPDYHSYMTYERSS 363

Query: 129 SLS 131
           + S
Sbjct: 364 ASS 366


>CHD1_MOUSE (P40201) Chromodomain-helicase-DNA-binding protein 1
           (CHD-1)
          Length = 1711

 Score = 30.0 bits (66), Expect = 2.3
 Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 14/96 (14%)

Query: 25  SSQGKELEFDEADVWNMSYSNSNTNI------EPKKGVPGLKRVSRKMEANNKVNPLASS 78
           SS G + +    + W MS S S + +      E ++            E  NKV     S
Sbjct: 134 SSSGAKRKKHNDEDWQMSGSGSPSQLGSDSESEEERDKSSCDGTESDYEPKNKVR----S 189

Query: 79  SLPMN---IPDWSKILKEEYKKKKESSDDEDEGDYD 111
             P N     +  KIL ++ K++ +SS+DED+ DYD
Sbjct: 190 RKPQNRSKSKNGKKILGQK-KRQIDSSEDEDDEDYD 224


>TP2B_CRILO (Q64399) DNA topoisomerase II, beta isozyme (EC 5.99.1.3)
          Length = 1612

 Score = 29.6 bits (65), Expect = 3.0
 Identities = 28/113 (24%), Positives = 46/113 (39%), Gaps = 16/113 (14%)

Query: 15   IFPETNFNQKSSQGKEL----EFDEADVWNMSYSNSNTNIEPKKGV------------PG 58
            +F   +++QKS          E D A V+  S+    T+  P K V            P 
Sbjct: 1434 LFSFPSYSQKSEDDSAKFDSNEEDTASVFTPSFGLKQTDKVPSKTVAAKKGKPPSDTAPK 1493

Query: 59   LKRVSRKMEANNKVNPLASSSLPMNIPDWSKILKEEYKKKKESSDDEDEGDYD 111
             KR  ++ +    VN  + S   +     +   K    KK+++S  E+EGDY+
Sbjct: 1494 AKRAPKQKKVVETVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYN 1546


>TOP1_YEAST (P04786) DNA topoisomerase I (EC 5.99.1.2)
          Length = 769

 Score = 29.6 bits (65), Expect = 3.0
 Identities = 21/91 (23%), Positives = 37/91 (40%), Gaps = 21/91 (23%)

Query: 38  VWNMSYSNSNTNIEPKKGVPGLKRVSRKMEANNKVNPLASSSLP---------------- 81
           V +M+ ++     EP      + ++S+K     K  P+ SSSLP                
Sbjct: 32  VASMNSASLQDEAEPYDSDEAISKISKKKTKKIKTEPVQSSSLPSPPAKKSATSKPKKIK 91

Query: 82  -----MNIPDWSKILKEEYKKKKESSDDEDE 107
                + +    K  +E  KKK+E  ++ED+
Sbjct: 92  KEDGDVKVKTTKKEEQENEKKKREEEEEEDK 122


>DEK_HUMAN (P35659) DEK protein
          Length = 375

 Score = 29.6 bits (65), Expect = 3.0
 Identities = 23/104 (22%), Positives = 46/104 (44%), Gaps = 5/104 (4%)

Query: 52  PKKGVPGLKRVSRKMEANNKVNPLASSSLPMNIPDWSKILKEEYKKKKESSDDEDEGDYD 111
           PK      K   ++  ++        +  P  + D S   ++E K K+ESSDDED+   +
Sbjct: 194 PKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEE 253

Query: 112 GVVQLPPHEYLARTRGASLSVHEGKGRTLKGRDLRSVRNAIWKK 155
                PP +   R +    +  + K +++K  +++   ++  KK
Sbjct: 254 E----PPKKTAKREKPKQKATSKSK-KSVKSANVKKADSSTTKK 292


>CHD1_HUMAN (O14646) Chromodomain-helicase-DNA-binding protein 1
           (CHD-1)
          Length = 1709

 Score = 29.6 bits (65), Expect = 3.0
 Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 14/99 (14%)

Query: 22  NQKSSQGKELEFDEADVWNMS------YSNSNTNIEPKKGVPGLKRVSRKMEANNKVNPL 75
           +  SS+ K  +  + D W MS       S S++  E ++            E  NKV   
Sbjct: 133 DDSSSEVKRKKHKDED-WQMSGSGSPSQSGSDSESEEEREKSSCDETESDYEPKNKVK-- 189

Query: 76  ASSSLPMN---IPDWSKILKEEYKKKKESSDDEDEGDYD 111
             S  P N     +  KIL ++ ++   S +D+DE DYD
Sbjct: 190 --SRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYD 226


>RA54_SCHPO (P41410) DNA repair protein rhp54 (EC 3.6.1.-) (RAD54
           homolog 1)
          Length = 852

 Score = 29.3 bits (64), Expect = 4.0
 Identities = 17/40 (42%), Positives = 21/40 (52%), Gaps = 9/40 (22%)

Query: 84  IPDWSKILKEEYKK---------KKESSDDEDEGDYDGVV 114
           IPD  ++L E+ KK         KKE SD E E D+D  V
Sbjct: 168 IPDIKEVLAEKRKKDELLKNRKGKKEISDSEPESDHDSCV 207


>MSH3_YEAST (P25336) MUTS protein homolog 3 (Mismatch binding
           protein) (MBP)
          Length = 1047

 Score = 29.3 bits (64), Expect = 4.0
 Identities = 30/97 (30%), Positives = 45/97 (45%), Gaps = 12/97 (12%)

Query: 22  NQKSSQGKELEFDEADVWNMSYSNSNTNIE-PKKGVPGLKRVSRKMEANNKVNPLASSSL 80
           N   S+   L+ DE D  +   S + TN   P KG      VS K   N++    + +S 
Sbjct: 60  NGAGSESICLDTDEEDNLSSVASTTVTNDSFPLKG-----SVSSKNSKNSEKT--SGTST 112

Query: 81  PMNIPDWSK----ILKEEYKKKKESSDDEDEGDYDGV 113
             N  D++K    I+K    +  E+ DDE+EG+ D V
Sbjct: 113 TFNDIDFAKKLDRIMKRRSDENVEAEDDEEEGEEDFV 149


>FRPC_NEIMC (P55127) Iron-regulated protein frpC
          Length = 1829

 Score = 29.3 bits (64), Expect = 4.0
 Identities = 24/89 (26%), Positives = 42/89 (46%), Gaps = 7/89 (7%)

Query: 38  VWNMSYSNSNTNIEPKKGVPGLKRVSRKMEANNKVNPLASSS---LPMNIPDWSKILKEE 94
           ++N    N++  IE  KGV  +K +S KM+  N  + LA  S       + D ++  KE 
Sbjct: 291 IYNDIVDNTSQGIE--KGVKAIKELSEKMK--NAASDLADGSAEKAKQVVEDLAQAAKEA 346

Query: 95  YKKKKESSDDEDEGDYDGVVQLPPHEYLA 123
           Y+  K +++   +   +    LP  + LA
Sbjct: 347 YENAKSTAEKAAQAAREFFKGLPSFKDLA 375


>FRPC_NEIMB (Q9JYV5) Iron-regulated protein frpC
          Length = 1829

 Score = 29.3 bits (64), Expect = 4.0
 Identities = 24/89 (26%), Positives = 42/89 (46%), Gaps = 7/89 (7%)

Query: 38  VWNMSYSNSNTNIEPKKGVPGLKRVSRKMEANNKVNPLASSS---LPMNIPDWSKILKEE 94
           ++N    N++  IE  KGV  +K +S KM+  N  + LA  S       + D ++  KE 
Sbjct: 291 IYNDIVDNTSQGIE--KGVKAIKELSEKMK--NAASDLADGSAEKAKQVVEDLAQAAKEA 346

Query: 95  YKKKKESSDDEDEGDYDGVVQLPPHEYLA 123
           Y+  K +++   +   +    LP  + LA
Sbjct: 347 YENAKSTAEKAAQAAREFFKGLPSFKDLA 375


>ATRX_MOUSE (Q61687) Transcriptional regulator ATRX (X-linked
           nuclear protein) (Heterochromatin protein 2) (HP1
           alpha-interacting protein) (HP1-BP38 protein)
          Length = 2476

 Score = 29.3 bits (64), Expect = 4.0
 Identities = 38/147 (25%), Positives = 59/147 (39%), Gaps = 18/147 (12%)

Query: 18  ETNFNQKSSQGKELEFDEADVWNMSYSNSNTNIEPKKGVPG-LKRVSRKMEANNKVNPLA 76
           E   N K   GK    D+        S S ++ + KKG       +S+K   N   +   
Sbjct: 744 EPQMNHKGKTGK----DDNGKRKRKNSTSGSDFDTKKGKSTETSIISKKKRQNYSESSNY 799

Query: 77  SSSLPMNIPDWSKI----LKEEYKKKKESSDDEDEGDYDGVVQLPPHEYLARTRGASLSV 132
            S L   I   S+I         KK+++SS+DE +G    VV    HE    T+  S + 
Sbjct: 800 DSELEREIKTMSRIGAARKSVPEKKEEDSSEDEKQG--KKVVDNGGHERAKTTQEGSSAD 857

Query: 133 HEG--KGR-----TLKGRDLRSVRNAI 152
             G  +GR     ++ G  +  VR+ +
Sbjct: 858 DTGDTEGRQGGSCSIAGGSIEKVRSGV 884


>NP14_RAT (P41777) Nucleolar phosphoprotein p130 (Nucleolar 130 kDa
           protein) (140 kDa nucleolar phosphoprotein) (Nopp140)
           (Nucleolar and coiled-body phosphoprotein 1)
          Length = 704

 Score = 28.9 bits (63), Expect = 5.2
 Identities = 14/47 (29%), Positives = 22/47 (46%)

Query: 90  ILKEEYKKKKESSDDEDEGDYDGVVQLPPHEYLARTRGASLSVHEGK 136
           + K+  K+   S   ED  + +   Q+P  +  A  + ASL  H GK
Sbjct: 74  VAKKAKKETSSSDSSEDSSEEEDKAQVPTQKAAAPAKRASLPQHAGK 120


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.308    0.128    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,776,932
Number of Sequences: 164201
Number of extensions: 830506
Number of successful extensions: 2861
Number of sequences better than 10.0: 44
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 2842
Number of HSP's gapped (non-prelim): 53
length of query: 160
length of database: 59,974,054
effective HSP length: 101
effective length of query: 59
effective length of database: 43,389,753
effective search space: 2559995427
effective search space used: 2559995427
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 61 (28.1 bits)