BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC148994.8 - phase: 0 /pseudo
(569 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
C972_SOYBN (O48921) Cytochrome P450 97B2 (EC 1.14.-.-) 353 9e-97
C973_ARATH (O23365) Cytochrome P450 97B3 (EC 1.14.-.-) 352 2e-96
C971_PEA (Q43078) Cytochrome P450 97B1 (EC 1.14.-.-) (P450 97A2) 343 5e-94
CPXB_BACME (P14779) Bifunctional P-450:NADPH-P450 reductase (Cyt... 137 6e-32
CYPE_BACSU (O08336) Probable bifunctional P-450:NADPH-P450 reduc... 133 1e-30
CP4C_BLADI (P29981) Cytochrome P450 4C1 (EC 1.14.14.1) (CYPIVC1) 132 2e-30
C4S3_DROME (Q9VXY0) Probable cytochrome P450 4s3 (EC 1.14.-.-) (... 127 6e-29
CPFB_HUMAN (Q9HBI6) Cytochrome P450 4F11 (EC 1.14.14.1) (CYPIVF11) 124 7e-28
C4CU_BLAGE (Q964T1) Cytochrome P450 4c21 (EC 1.14.14.1) (CYPIVC21) 124 7e-28
CPFC_HUMAN (Q9HCS2) Cytochrome P450 4F12 (EC 1.14.14.1) (CYPIVF1... 123 1e-27
C132_MYCTU (P77900) Putative cytochrome P450 132 (EC 1.14.-.-) 122 2e-27
C132_MYCBO (P59954) Putative cytochrome P450 132 (EC 1.14.-.-) 122 2e-27
CPF2_HUMAN (P78329) Cytochrome P450 4F2 (EC 1.14.13.30) (CYPIVF2... 121 6e-27
CPF1_RAT (P33274) Cytochrome P450 4F1 (EC 1.14.14.1) (CYPIVF1) (... 120 7e-27
CYPD_BACSU (O08394) Probable bifunctional P-450:NADPH-P450 reduc... 119 2e-26
C941_VICSA (O81117) Cytochrome P450 94A1 (EC 1.14.-.-) (P450-dep... 117 6e-26
CPFE_MOUSE (Q9EP75) Cytochrome P450 4F14 (EC 1.14.13.30) (Leukot... 117 8e-26
CPF3_HUMAN (Q08477) Cytochrome P450 4F3 (EC 1.14.13.30) (CYPIVF3... 117 1e-25
CPF8_HUMAN (P98187) Cytochrome P450 4F8 (EC 1.14.14.1) (CYPIVF8) 116 2e-25
C4AE_DROME (O46054) Cytochrome P450 4ae1 (EC 1.14.-.-) (CYPIVAE1) 115 3e-25
>C972_SOYBN (O48921) Cytochrome P450 97B2 (EC 1.14.-.-)
Length = 576
Score = 353 bits (905), Expect = 9e-97
Identities = 197/416 (47%), Positives = 273/416 (65%), Gaps = 23/416 (5%)
Query: 169 KKSLSNL--GVSNEILEFLFG-LYPKIPEAKGSISAIRSEAFFIPLYELYITYGGIFRLN 225
KKS NL SN + + L G +P A+G++S + F LY+ ++ +G +++L
Sbjct: 53 KKSSRNLLGNASNLLTDLLSGGSIGSMPIAEGAVSDLLGRPLFFSLYDWFLEHGAVYKLA 112
Query: 226 FGPKSFLIVSDPAIAKHILKDNSKAYSKGILAEILDFVMGKGLIPADGEIWRVRRRTIVP 285
FGPK+F++VSDP +A+HIL++N+ +Y KG+LA+IL+ +MGKGLIPAD + W+ RRR I P
Sbjct: 113 FGPKAFVVVSDPIVARHILRENAFSYDKGVLADILEPIMGKGLIPADLDTWKQRRRVIAP 172
Query: 286 ALHLKFVAAMIGLFGQATDRLCQK----LDTAASDGED---VEMESLFSRLTLDVIGKAV 338
A H ++ AM+ +F ++R K L+ DG D +++E+ FS L LD+IG V
Sbjct: 173 AFHNSYLEAMVKIFTTCSERTILKFNKLLEGEGYDGPDSIELDLEAEFSSLALDIIGLGV 232
Query: 339 FNYDFDSLSNDTGIIEAVYTVLREAEDRSISPIPVWDLPIWKDISPRQRKVTAALKLVND 398
FNYDF S++ ++ +I+AVY L EAE RS IP W +P+ + I PRQRK LK++N
Sbjct: 233 FNYDFGSVTKESPVIKAVYGTLFEAEHRSTFYIPYWKIPLARWIVPRQRKFQDDLKVINT 292
Query: 399 TLNNLIAICKRM---VDEEELQFHEEYMNEQDPSILHFLL-ASGDDVTSKQLRDDLMTML 454
L+ LI K D E+LQ +Y+N +D S+L FL+ G DV +QLRDDLMTML
Sbjct: 293 CLDGLIRNAKESRQETDVEKLQ-QRDYLNLKDASLLRFLVDMRGADVDDRQLRDDLMTML 351
Query: 455 IAGHETSAAVLTWTFYLLSKEPSVMSKLQEEVDSVLGDRFPTIEDMKKLKYTTRVINESL 514
IAGHET+AAVLTW +LL++ PS M K Q EVD VLG PT E +K+L+Y ++ E+L
Sbjct: 352 IAGHETTAAVLTWAVFLLAQNPSKMKKAQAEVDLVLGTGRPTFESLKELQYIRLIVVEAL 411
Query: 515 RLYPQPPVLIRRSIEDDVL-----GE---YPIKRGEDIFISVWNLHRSPTLWNDAD 562
RLYPQPP+LIRRS++ DVL GE Y I G D+FISV+NLHRSP W+ D
Sbjct: 412 RLYPQPPLLIRRSLKSDVLPGGHKGEKDGYAIPAGTDVFISVYNLHRSPYFWDRPD 467
>C973_ARATH (O23365) Cytochrome P450 97B3 (EC 1.14.-.-)
Length = 580
Score = 352 bits (902), Expect = 2e-96
Identities = 198/439 (45%), Positives = 284/439 (64%), Gaps = 33/439 (7%)
Query: 143 RRAELSAKIASGEFTVKQESGLPSILKKSLSNLGVSNEILEFLFG-LYPKIPEAKGSISA 201
RRA +S K S E P L N SN + FL G +P A+GS+S
Sbjct: 45 RRASVSIKCQSTE---------PKTNGNILDN--ASNLLTNFLSGGSLGSMPTAEGSVSD 93
Query: 202 IRSEAFFIPLYELYITYGGIFRLNFGPKSFLIVSDPAIAKHILKDNSKAYSKGILAEILD 261
+ + F+ LY+ ++ +GGI++L FGPK+F+++SDP IA+H+L++N+ +Y KG+LAEIL+
Sbjct: 94 LFGKPLFLSLYDWFLEHGGIYKLAFGPKAFVVISDPIIARHVLRENAFSYDKGVLAEILE 153
Query: 262 FVMGKGLIPADGEIWRVRRRTIVPALHLKFVAAMIGLFGQATDRLCQK-----LDTAASD 316
+MGKGLIPAD + W++RRR I PA H ++ AM+ +F ++++ K + S
Sbjct: 154 PIMGKGLIPADLDTWKLRRRAITPAFHKLYLEAMVKVFSDCSEKMILKSEKLIREKETSS 213
Query: 317 GED---VEMESLFSRLTLDVIGKAVFNYDFDSLSNDTGIIEAVYTVLREAEDRSISPIPV 373
GED +++E+ FS L LD+IG +VFNYDF S++ ++ +I+AVY L EAE RS P
Sbjct: 214 GEDTIELDLEAEFSSLALDIIGLSVFNYDFGSVTKESPVIKAVYGTLFEAEHRSTFYFPY 273
Query: 374 WDLPIWKDISPRQRKVTAALKLVNDTLNNLIAICK---RMVDEEELQFHEEYMNEQDPSI 430
W+ P + I PRQRK + LK++ND L+ LI K + D E+LQ +Y N +D S+
Sbjct: 274 WNFPPARWIVPRQRKFQSDLKIINDCLDGLIQNAKETRQETDVEKLQ-ERDYTNLKDASL 332
Query: 431 LHFLL-ASGDDVTSKQLRDDLMTMLIAGHETSAAVLTWTFYLLSKEPSVMSKLQEEVDSV 489
L FL+ G D+ +QLRDDLMTMLIAGHET+AAVLTW +LLS+ P + K Q E+D+V
Sbjct: 333 LRFLVDMRGVDIDDRQLRDDLMTMLIAGHETTAAVLTWAVFLLSQNPEKIRKAQAEIDAV 392
Query: 490 LGDRFPTIEDMKKLKYTTRVINESLRLYPQPPVLIRRSIEDDVL-----GE---YPIKRG 541
LG PT E MKKL+Y ++ E LRL+PQPP+LIRR+++ + L GE + + +G
Sbjct: 393 LGQGPPTYESMKKLEYIRLIVVEVLRLFPQPPLLIRRTLKPETLPGGHKGEKEGHKVPKG 452
Query: 542 EDIFISVWNLHRSPTLWND 560
DIFISV+NLHRSP W++
Sbjct: 453 TDIFISVYNLHRSPYFWDN 471
>C971_PEA (Q43078) Cytochrome P450 97B1 (EC 1.14.-.-) (P450 97A2)
Length = 552
Score = 343 bits (881), Expect = 5e-94
Identities = 191/413 (46%), Positives = 268/413 (64%), Gaps = 23/413 (5%)
Query: 169 KKSLSNL--GVSNEILEFLFGL-YPKIPEAKGSISAIRSEAFFIPLYELYITYGGIFRLN 225
K+S N+ SN + L G +P A+G+++ + F LY+ ++ +G +++L
Sbjct: 62 KQSSRNVFDNASNLLTSLLSGANLGSMPIAEGAVTDLFDRPLFFSLYDWFLEHGSVYKLA 121
Query: 226 FGPKSFLIVSDPAIAKHILKDNSKAYSKGILAEILDFVMGKGLIPADGEIWRVRRRTIVP 285
FGPK+F++VSDP +A+HIL++N+ +Y KG+LA+IL+ +MGKGLIPAD E W+ RRR I P
Sbjct: 122 FGPKAFVVVSDPIVARHILRENAFSYDKGVLADILEPIMGKGLIPADLETWKQRRRVIAP 181
Query: 286 ALHLKFVAAMIGLFGQATDRLCQK----LDTAASDGE---DVEMESLFSRLTLDVIGKAV 338
H ++ AM+ LF ++R K L+ DG+ ++++E+ FS L L++IG V
Sbjct: 182 GFHTSYLEAMVQLFTSCSERTVLKVNELLEGEGRDGQKSVELDLEAEFSNLALEIIGLGV 241
Query: 339 FNYDFDSLSNDTGIIEAVYTVLREAEDRSISPIPVWDLPIWKDISPRQRKVTAALKLVND 398
FNYDF S++N++ +I+AVY L EAE RS IP W P+ + I PRQRK LK++N
Sbjct: 242 FNYDFGSVTNESPVIKAVYGTLFEAEHRSTFYIPYWKFPLARWIVPRQRKFQDDLKVINT 301
Query: 399 TLNNLIAICK---RMVDEEELQFHEEYMNEQDPSILHFLL-ASGDDVTSKQLRDDLMTML 454
L+ LI K + D E+LQ +Y N +D S+L FL+ G DV +QLRDDLMTML
Sbjct: 302 CLDGLIRNAKESRQETDVEKLQ-QRDYSNLKDASLLRFLVDMRGVDVDDRQLRDDLMTML 360
Query: 455 IAGHETSAAVLTWTFYLLSKEPSVMSKLQEEVDSVLGDRFPTIEDMKKLKYTTRVINESL 514
IAGHET+AAVLTW +LL++ P M K Q EVD VLG PT E +KKL+Y ++ E+L
Sbjct: 361 IAGHETTAAVLTWAVFLLAQNPDKMKKAQAEVDLVLGMGKPTFELLKKLEYIRLIVVETL 420
Query: 515 RLYPQPPVLIRRSIEDDVL--------GEYPIKRGEDIFISVWNLHRSPTLWN 559
RLYPQPP+LIRRS++ DVL Y I G D+FISV+NLHRSP W+
Sbjct: 421 RLYPQPPLLIRRSLKPDVLPGGHKGDKDGYTIPAGTDVFISVYNLHRSPYFWD 473
>CPXB_BACME (P14779) Bifunctional P-450:NADPH-P450 reductase
(Cytochrome P450(BM-3)) (P450BM-3) [Includes: Cytochrome
P450 102 (EC 1.14.14.1); NADPH--cytochrome P450
reductase (EC 1.6.2.4)]
Length = 1048
Score = 137 bits (346), Expect = 6e-32
Identities = 97/314 (30%), Positives = 165/314 (51%), Gaps = 24/314 (7%)
Query: 256 LAEILDFVM---GKGLIPA--DGEIWRVRRRTIVPALHLKFVAAMIGLFGQATDRLCQKL 310
L++ L FV G GL + + W+ ++P+ + + + +L QK
Sbjct: 71 LSQALKFVRDFAGDGLFTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKW 130
Query: 311 DTAASDGEDVEMESLFSRLTLDVIGKAVFNYDFDSLSNDTG--IIEAVYTVLREAEDRSI 368
+ +D E +E+ +RLTLD IG FNY F+S D I ++ L EA ++
Sbjct: 131 ERLNAD-EHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQ 189
Query: 369 SPIPVWDLPIWKDISPRQRKVTAALKLVNDTLNNLIAICKRMVDE-EELQFHEEYMNEQD 427
P D P + + +R+ +K++ND ++ +IA K ++ ++L H +N +D
Sbjct: 190 RANP--DDPAYDE---NKRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTH--MLNGKD 242
Query: 428 PSILHFLLASGDDVTSKQLRDDLMTMLIAGHETSAAVLTWTFYLLSKEPSVMSKLQEEVD 487
P +G+ + + +R ++T LIAGHET++ +L++ Y L K P V+ K EE
Sbjct: 243 PE-------TGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAAEEAA 295
Query: 488 SVLGDRFPTIEDMKKLKYTTRVINESLRLYPQPPVLIRRSIEDDVL-GEYPIKRGEDIFI 546
VL D P+ + +K+LKY V+NE+LRL+P P + ED VL GEYP+++G+++ +
Sbjct: 296 RVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMV 355
Query: 547 SVWNLHRSPTLWND 560
+ LHR T+W D
Sbjct: 356 LIPQLHRDKTIWGD 369
>CYPE_BACSU (O08336) Probable bifunctional P-450:NADPH-P450
reductase 2 [Includes: Cytochrome P450 102 (EC
1.14.14.1); NADPH--cytochrome P450 reductase (EC
1.6.2.4)]
Length = 1054
Score = 133 bits (335), Expect = 1e-30
Identities = 106/376 (28%), Positives = 179/376 (47%), Gaps = 22/376 (5%)
Query: 190 PKIPEAKGSISAIRSEAFFIPLYELYITYGGIFRLNFGPKSFLIVSDPAIAKHILKDN-- 247
PK ++ + E L+ + G IFR +F S + VS + + +
Sbjct: 10 PKTYGPLKNLPHLEKEQLSQSLWRIADELGPIFRFDFPGVSSVFVSGHNLVAEVCDEKRF 69
Query: 248 SKAYSKGILAEILDFVMGKGLIPA--DGEIWRVRRRTIVPALHLKFVAAMIGLFGQATDR 305
K KG L ++ +F G GL + W+ R ++P+ K + + +
Sbjct: 70 DKNLGKG-LQKVREFG-GDGLFTSWTHEPNWQKAHRILLPSFSQKAMKGYHSMMLDIATQ 127
Query: 306 LCQKLDTAASDGEDVEMESLFSRLTLDVIGKAVFNYDFDSLSNDTG--IIEAVYTVLREA 363
L QK + + E++++ +RLTLD IG FNY F+S D+ I ++ L+EA
Sbjct: 128 LIQKW-SRLNPNEEIDVADDMTRLTLDTIGLCGFNYRFNSFYRDSQHPFITSMLRALKEA 186
Query: 364 EDRSISPIPVWDLPIWKDISPRQRKVTAALKLVNDTLNNLIAICKRMVDEEELQFHEEYM 423
++S + + D + K Q+ + +++N ++ +IA K DE +
Sbjct: 187 MNQS-KRLGLQDKMMVKTKLQFQKDI----EVMNSLVDRMIAERKANPDENIKDLLSLML 241
Query: 424 NEQDPSILHFLLASGDDVTSKQLRDDLMTMLIAGHETSAAVLTWTFYLLSKEPSVMSKLQ 483
+DP +G+ + + +R ++T LIAGHET++ +L++ Y L P + K Q
Sbjct: 242 YAKDP-------VTGETLDDENIRYQIITFLIAGHETTSGLLSFAIYCLLTHPEKLKKAQ 294
Query: 484 EEVDSVLGDRFPTIEDMKKLKYTTRVINESLRLYPQPPVLIRRSIEDDVL-GEYPIKRGE 542
EE D VL D P + +++LKY V+NE+LRLYP P + ED VL GEYPI +G+
Sbjct: 295 EEADRVLTDDTPEYKQIQQLKYIRMVLNETLRLYPTAPAFSLYAKEDTVLGGEYPISKGQ 354
Query: 543 DIFISVWNLHRSPTLW 558
+ + + LHR W
Sbjct: 355 PVTVLIPKLHRDQNAW 370
>CP4C_BLADI (P29981) Cytochrome P450 4C1 (EC 1.14.14.1) (CYPIVC1)
Length = 511
Score = 132 bits (333), Expect = 2e-30
Identities = 89/363 (24%), Positives = 178/363 (48%), Gaps = 22/363 (6%)
Query: 218 YGGIFRLNFGPKSFLIVSDPAIAKHILKDNSKAYSKGILAEILDFVMGKGLIPADGEIWR 277
YG ++R+ GP + + ++ P + IL+D +K K ++ + +G+GL+ G W
Sbjct: 70 YGPLYRIWAGPIAQVGLTRPEHVELILRD-TKHIDKSLVYSFIRPWLGEGLLTGTGAKWH 128
Query: 278 VRRRTIVPALHLKFVAAMIGLFGQATDRLCQKLDTAASDGEDVEMESLFSRLTLDVIGKA 337
R+ I P H K + + +F + ++ L +KL + G+D ++ + LD+I +
Sbjct: 129 SHRKMITPTFHFKILDIFVDVFVEKSEILVKKLQSKVG-GKDFDIYPFITHCALDIICET 187
Query: 338 VFNYDFDSLS-NDTGIIEAVYTVLREAEDRSISPIPVWDLP-IWKDISPRQRKVTAALKL 395
++ +++ ++AVY + RS+ P W P + D++ ++ L++
Sbjct: 188 AMGIQMNAQEESESEYVKAVYEISELTMQRSVRP---WLHPKVIFDLTTMGKRYAECLRI 244
Query: 396 VNDTLNNLIAICKRMVDEEELQFHEEYMNEQDP--------SILHFLLAS---GDDVTSK 444
++ N +I K + + NE+D + L LL + G ++
Sbjct: 245 LHGFTNKVIQERKSL--RQMTGMKPTISNEEDELLGKKKRLAFLDLLLEASENGTKMSDT 302
Query: 445 QLRDDLMTMLIAGHETSAAVLTWTFYLLSKEPSVMSKLQEEVDSVL--GDRFPTIEDMKK 502
+R+++ T + GH+T++A + W +LL P + K+ EE+D + DR T+ D+
Sbjct: 303 DIREEVDTFMFEGHDTTSAGICWALFLLGSHPEIQDKVYEELDHIFQGSDRSTTMRDLAD 362
Query: 503 LKYTTRVINESLRLYPQPPVLIRRSIEDDVLGEYPIKRGEDIFISVWNLHRSPTLWNDAD 562
+KY RVI ESLRL+P P + R ED +G+Y + G + + ++++HR+ + + +
Sbjct: 363 MKYLERVIKESLRLFPSVPFIGRVLKEDTKIGDYLVPAGCMMNLQIYHVHRNQDQYPNPE 422
Query: 563 KLN 565
N
Sbjct: 423 AFN 425
>C4S3_DROME (Q9VXY0) Probable cytochrome P450 4s3 (EC 1.14.-.-)
(CYPIVS3)
Length = 495
Score = 127 bits (320), Expect = 6e-29
Identities = 96/369 (26%), Positives = 179/369 (48%), Gaps = 28/369 (7%)
Query: 211 LYELYITYGGIFRLNFGPKSFLIVSDPAIAKHILKDNSKAYSKGILAEILDFVMGKGLIP 270
L EL +G +FR+ FG ++ +DP K +L N++ +K E+L+ +GKGL+
Sbjct: 56 LKELREKHGPVFRIWFGKDLMVMFTDPEDIKQLL-GNNQLLTKSRNYELLEPWLGKGLLT 114
Query: 271 ADGEIWRVRRRTIVPALHLKFVAAMIGLFGQATDRLCQKLDTAASDGEDVEMESLFSRLT 330
GE W RR+ + P H + ++ + L ++L T A+ GE ++ +
Sbjct: 115 NGGESWHRRRKLLTPGFHFRILSEFKEPMEENCRILVRRLRTKAN-GESFDIYPYITLFA 173
Query: 331 LDVIGKAVFNYDFDS-LSNDTGIIEAVYTVLREAEDRSISPIPVWDL--PIWKDISPRQR 387
LD I + + L +D+ ++AV ++ R +S S W +K P +
Sbjct: 174 LDAICETAMGIKKHAQLQSDSEYVQAVQSICRVMHKQSFS---FWQRLNVFFKHTKPGKE 230
Query: 388 KVTAALKLVNDTLNNLIAICKRMVDEEELQFHEEYMNEQDP-------SILHFLLAS--- 437
+ AALK+++D N +I + + + +E ++ E EQD + L LL +
Sbjct: 231 R-EAALKVLHDETNRVIRLRREQLIQERNEWKPEA--EQDDVGAKRRLAFLDMLLLTQME 287
Query: 438 -GDDVTSKQLRDDLMTMLIAGHETSAAVLTWTFYLLSKEPSVMSKLQEEVDSVLGDRFPT 496
G +++ +R+++ T + GH+T+++ + + LLSK P V + EE + G
Sbjct: 288 GGAELSDTDIREEVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEEASELEG----- 342
Query: 497 IEDMKKLKYTTRVINESLRLYPQPPVLIRRSIEDDVLGEYPIKRGEDIFISVWNLHRSPT 556
+ + + Y VI E+LR+YP P R+ +ED +G+ + +G I ++ LHR P
Sbjct: 343 -REKESMPYLEAVIKETLRIYPSVPFFSRKVLEDLEVGKLTVPKGASISCLIYMLHRDPK 401
Query: 557 LWNDADKLN 565
+ D ++ +
Sbjct: 402 NFPDPERFD 410
>CPFB_HUMAN (Q9HBI6) Cytochrome P450 4F11 (EC 1.14.14.1) (CYPIVF11)
Length = 524
Score = 124 bits (311), Expect = 7e-28
Identities = 98/364 (26%), Positives = 176/364 (47%), Gaps = 14/364 (3%)
Query: 211 LYELYITYGGIFRLNFGPK-SFLIVSDPAIAKHILKDNSKAYSKG-ILAEILDFVMGKGL 268
L +L TY F+L GP LI+ P I + I ++ K I L +G GL
Sbjct: 77 LTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGL 136
Query: 269 IPADGEIWRVRRRTIVPALHLKFVAAMIGLFGQATDRLCQKLDTAASDGED-VEMESLFS 327
+ + G+ W RR + PA H + + +F ++ + + K AS+G ++M S
Sbjct: 137 LLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHIS 196
Query: 328 RLTLDVIGKAVFNYDFDSLSNDTGIIEAVYTVLREAEDRSISPIPVWDLPIWKDISPRQR 387
+TLD + K VF+++ + + I A+ + E R+ + D + ++P +
Sbjct: 197 LMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYY--LTPDGQ 254
Query: 388 KVTAALKLVNDTLNNLIAICKRMVDEEELQ-FHEEYMNEQDPSILHFLLAS----GDDVT 442
+ A LV+D + +I +R + + + F + + + LL S G +++
Sbjct: 255 RFRRACHLVHDFTDAVIQERRRTLPTQGIDDFLKNKAKSKTLDFIDVLLLSKDEDGKELS 314
Query: 443 SKQLRDDLMTMLIAGHETSAAVLTWTFYLLSKEPSVMSKLQEEVDSVLGDRFP---TIED 499
+ +R + T + GH+T+A+ L+W Y L+K P + ++EV +L DR P +D
Sbjct: 315 DEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDD 374
Query: 500 MKKLKYTTRVINESLRLYPQPPVLIRRSIEDDVLGE-YPIKRGEDIFISVWNLHRSPTLW 558
+ +L + T I ESLRL+P PV+ R +D VL + I +G I++ +H +PT+W
Sbjct: 375 LAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVW 434
Query: 559 NDAD 562
D +
Sbjct: 435 PDPE 438
>C4CU_BLAGE (Q964T1) Cytochrome P450 4c21 (EC 1.14.14.1) (CYPIVC21)
Length = 501
Score = 124 bits (311), Expect = 7e-28
Identities = 93/357 (26%), Positives = 168/357 (47%), Gaps = 17/357 (4%)
Query: 213 ELYITYGGIFRLNFGPKSFLIVSDPAIAKHILKDNSKAYSKGILAEILDFVMGKGLIPAD 272
E+ Y + FG + F+ +S P + + +L+ N++ K L ++ +G GL+ +
Sbjct: 63 EILEKYKPLILWYFGNRPFVNISSPELIEVVLR-NTQLIDKAFLYDLFHSWLGTGLLTSS 121
Query: 273 GEIWRVRRRTIVPALHLKFVAAMIGLFGQATDRLCQKLDTAASDGEDVEMESLFSRLTLD 332
G W R+ I P H + I +F + ++ L +KL G + S LD
Sbjct: 122 GAKWHQHRKIITPTFHFSILEGFITIFAEKSEILVRKLQKEVGRGPFF-IRQYVSNCALD 180
Query: 333 VIGKAVFNYDFDSLSNDTGIIEAVYTVLREAE---DRSISPIPVWDLPIWKDISPRQRKV 389
+I + ++ D G E V + + + DR +P+ ++ I+K ++P
Sbjct: 181 IICETAMGTSVNA--QDEGFSEYVTAINKMTDVLSDRMANPL-LYPEFIFK-LTPYYWTH 236
Query: 390 TAALKLVNDTLNNLIAICKRMVDEEELQFHEEYMN----EQDPSILHFLLASGDD--VTS 443
LK++N +N +I K + ++ E + ++ P + L AS DD +T
Sbjct: 237 KKCLKVLNGFVNKIIQERKEERKKSKVTQTSEDADIGKKKRVPFLDTLLDASEDDNKLTD 296
Query: 444 KQLRDDLMTMLIAGHETSAAVLTWTFYLLSKEPSVMSKLQEEVDSVL--GDRFPTIEDMK 501
+ +++ T + GH+T +A +TW + L P + + +EV + DR PT+ D+
Sbjct: 297 TDILEEVHTFMFEGHDTVSAAMTWLLFELGHHPEIQEEAYKEVQDIFQGSDRVPTMADLN 356
Query: 502 KLKYTTRVINESLRLYPQPPVLIRRSIEDDVLGEYPIKRGEDIFISVWNLHRSPTLW 558
+ Y RVI ESLRL+P +R + +D LG Y I G +I SV +HR+P ++
Sbjct: 357 NMNYLERVIKESLRLHPSVIYFVREAHQDFELGGYTIPAGTNIDFSVPFIHRNPEIF 413
>CPFC_HUMAN (Q9HCS2) Cytochrome P450 4F12 (EC 1.14.14.1) (CYPIVF12)
(UNQ568/PRO1129)
Length = 524
Score = 123 bits (309), Expect = 1e-27
Identities = 90/362 (24%), Positives = 173/362 (46%), Gaps = 14/362 (3%)
Query: 213 ELYITYGGIFRLNFGPK-SFLIVSDPAIAKHILKDNSKAYSK-GILAEILDFVMGKGLIP 270
++ TY F + GP F+++ P + I ++ K + L +G+G++
Sbjct: 79 QMSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILL 138
Query: 271 ADGEIWRVRRRTIVPALHLKFVAAMIGLFGQATDRLCQKLDTAASDGED-VEMESLFSRL 329
+ G+ W RR + PA H + + I +F ++ + + K AS+G ++M S +
Sbjct: 139 SGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLM 198
Query: 330 TLDVIGKAVFNYDFDSLSNDTGIIEAVYTVLREAEDRSISPIPVWDLPIWKDISPRQRKV 389
TLD + K +F++D + I + + E RS + D + +S R+
Sbjct: 199 TLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHILQHMDFLYY--LSHDGRRF 256
Query: 390 TAALKLVNDTLNNLIAICKRMVDEEELQ-FHEEYMNEQDPSILHFLLASGDD----VTSK 444
A +LV+D + +I +R + + + F ++ + + LL S D+ ++ +
Sbjct: 257 HRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDE 316
Query: 445 QLRDDLMTMLIAGHETSAAVLTWTFYLLSKEPSVMSKLQEEVDSVLGDRFP---TIEDMK 501
+R + T + GH+T+A+ L+W Y L++ P + ++EV +L DR P +D+
Sbjct: 317 DIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLA 376
Query: 502 KLKYTTRVINESLRLYPQPPVLIRRSIEDDVLGE-YPIKRGEDIFISVWNLHRSPTLWND 560
+L + T + ESLRL+P P + R +D VL + I +G I + +H +PT+W D
Sbjct: 377 QLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPD 436
Query: 561 AD 562
+
Sbjct: 437 PE 438
>C132_MYCTU (P77900) Putative cytochrome P450 132 (EC 1.14.-.-)
Length = 461
Score = 122 bits (307), Expect = 2e-27
Identities = 90/357 (25%), Positives = 163/357 (45%), Gaps = 31/357 (8%)
Query: 221 IFRLNFGPKSFLIVSDPAIAKHILKDNSKAYSKGILAEILDFVMGKGLIPADGEIWRVRR 280
I R + F+ +S P H+L + Y K + G L+ +G+ W R
Sbjct: 46 ITRFRCAGRRFVSISHPDYVDHVLHEARLKYVKSDEYGPIRATAGLNLLTDEGDSWARHR 105
Query: 281 RTIVPALHLKFVAAMIGLFGQATDRLCQKLDTAASDGEDVEMESLFSRLTLDVIGKAVFN 340
+ + + ++GL D + + A G +M TL V+ A+F+
Sbjct: 106 GALNSTFARRHLRGLVGLM---IDPIAD-VTAARVPGAQFDMHQSMVETTLRVVANALFS 161
Query: 341 YDFDSLSNDTGIIEAVYTVLREAEDRS------ISPIPVWDLPIW-----KDISPRQRKV 389
DF L + + LR AE + P V+D IW + P R++
Sbjct: 162 QDFGPLVQS--MHDLATRGLRRAEKLERLGLWGLMPRTVYDTLIWCIYSGVHLPPPLREM 219
Query: 390 TAALKLVNDTLNNLIAICKRMVDEEELQFHEEYMNEQDPSILHFLLASGDDVTSKQ-LRD 448
++ +N++I +R+ E N D +L+ LL++ + +Q +RD
Sbjct: 220 QEITLTLDRAINSVID--RRLA---------EPTNSAD--LLNVLLSADGGIWPRQRVRD 266
Query: 449 DLMTMLIAGHETSAAVLTWTFYLLSKEPSVMSKLQEEVDSVLGDRFPTIEDMKKLKYTTR 508
+ +T ++AGHET+A ++W +YL++ P + E+D VLG R PT +D+ KL +TT
Sbjct: 267 EALTFMLAGHETTANAMSWFWYLMALNPQARDHMLTELDDVLGMRRPTADDLGKLAWTTA 326
Query: 509 VINESLRLYPQPPVLIRRSIEDDVLGEYPIKRGEDIFISVWNLHRSPTLWNDADKLN 565
+ ES R + ++ R +++DD++ + I+RG + I + ++H P W D D+ +
Sbjct: 327 CLQESQRYFSSVWIIAREAVDDDIIDGHRIRRGTTVVIPIHHIHHDPRWWPDPDRFD 383
>C132_MYCBO (P59954) Putative cytochrome P450 132 (EC 1.14.-.-)
Length = 461
Score = 122 bits (307), Expect = 2e-27
Identities = 90/357 (25%), Positives = 163/357 (45%), Gaps = 31/357 (8%)
Query: 221 IFRLNFGPKSFLIVSDPAIAKHILKDNSKAYSKGILAEILDFVMGKGLIPADGEIWRVRR 280
I R + F+ +S P H+L + Y K + G L+ +G+ W R
Sbjct: 46 ITRFRCAGRRFVSISHPDYVDHVLHEARLKYVKSDEYGPIRATAGLNLLTDEGDSWARHR 105
Query: 281 RTIVPALHLKFVAAMIGLFGQATDRLCQKLDTAASDGEDVEMESLFSRLTLDVIGKAVFN 340
+ + + ++GL D + + A G +M TL V+ A+F+
Sbjct: 106 GALNSTFARRHLRGLVGLM---IDPIAD-VTAALVPGAQFDMHQSMVETTLRVVANALFS 161
Query: 341 YDFDSLSNDTGIIEAVYTVLREAEDRS------ISPIPVWDLPIW-----KDISPRQRKV 389
DF L + + LR AE + P V+D IW + P R++
Sbjct: 162 QDFGPLVQS--MHDLATRGLRRAEKLERLGLWGLMPRTVYDTLIWCIYSGVHLPPPLREM 219
Query: 390 TAALKLVNDTLNNLIAICKRMVDEEELQFHEEYMNEQDPSILHFLLASGDDVTSKQ-LRD 448
++ +N++I +R+ E N D +L+ LL++ + +Q +RD
Sbjct: 220 QEITLTLDRAINSVID--RRLA---------EPTNSAD--LLNVLLSADGGIWPRQRVRD 266
Query: 449 DLMTMLIAGHETSAAVLTWTFYLLSKEPSVMSKLQEEVDSVLGDRFPTIEDMKKLKYTTR 508
+ +T ++AGHET+A ++W +YL++ P + E+D VLG R PT +D+ KL +TT
Sbjct: 267 EALTFMLAGHETTANAMSWFWYLMALNPQARDHMLTELDDVLGMRRPTADDLGKLAWTTA 326
Query: 509 VINESLRLYPQPPVLIRRSIEDDVLGEYPIKRGEDIFISVWNLHRSPTLWNDADKLN 565
+ ES R + ++ R +++DD++ + I+RG + I + ++H P W D D+ +
Sbjct: 327 CLQESQRYFSSVWIIAREAVDDDIIDGHRIRRGTTVVIPIHHIHHDPRWWPDPDRFD 383
>CPF2_HUMAN (P78329) Cytochrome P450 4F2 (EC 1.14.13.30) (CYPIVF2)
(Leukotriene-B(4) omega-hydroxylase) (Leukotriene-B(4)
20-monooxygenase) (Cytochrome P450-LTB-omega)
Length = 520
Score = 121 bits (303), Expect = 6e-27
Identities = 95/364 (26%), Positives = 174/364 (47%), Gaps = 14/364 (3%)
Query: 211 LYELYITYGGIFRLNFGPKSFLI-VSDPAIAKHILKDNSKAYSKG-ILAEILDFVMGKGL 268
L +L TY F++ GP S L+ + P I + ++ ++ K L+ +G GL
Sbjct: 77 LTQLVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGL 136
Query: 269 IPADGEIWRVRRRTIVPALHLKFVAAMIGLFGQATDRLCQKLDTAASDGED-VEMESLFS 327
+ + G+ W RR + PA H + + +F ++ + + K AS+G ++M S
Sbjct: 137 LLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHIS 196
Query: 328 RLTLDVIGKAVFNYDFDSLSNDTGIIEAVYTVLREAEDRSISPIPVWDLPIWKDISPRQR 387
+TLD + K VF++D + I A+ + R + D + ++P +
Sbjct: 197 LMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEILLHIDFLYY--LTPDGQ 254
Query: 388 KVTAALKLVNDTLNNLIAICKRMVDEEELQ-FHEEYMNEQDPSILHFLLASGDD----VT 442
+ A +LV+D + +I +R + + + F + + + LL S D+ ++
Sbjct: 255 RFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLS 314
Query: 443 SKQLRDDLMTMLIAGHETSAAVLTWTFYLLSKEPSVMSKLQEEVDSVLGDRFP---TIED 499
+ +R + T + GH+T+A+ L+W Y L+K P + ++EV +L DR P +D
Sbjct: 315 DEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDD 374
Query: 500 MKKLKYTTRVINESLRLYPQPPVLIRRSIEDDVLGE-YPIKRGEDIFISVWNLHRSPTLW 558
+ L + T + ESLRL+P PV+ R +D VL + I +G ISV+ H +P +W
Sbjct: 375 LAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVW 434
Query: 559 NDAD 562
D +
Sbjct: 435 PDPE 438
>CPF1_RAT (P33274) Cytochrome P450 4F1 (EC 1.14.14.1) (CYPIVF1)
(P450-A3)
Length = 524
Score = 120 bits (302), Expect = 7e-27
Identities = 95/367 (25%), Positives = 177/367 (47%), Gaps = 14/367 (3%)
Query: 211 LYELYITYGGIFRLNFGPKSFLI-VSDPAIAKHILKDNSKAYSKGILA-EILDFVMGKGL 268
L L TY F + GP +I + I + IL ++ K ++ IL +G GL
Sbjct: 77 LTRLVGTYPQGFLMWIGPMVPVITLCHSDIVRSILNASAAVALKDVIFYTILKPWLGDGL 136
Query: 269 IPADGEIWRVRRRTIVPALHLKFVAAMIGLFGQATDRLCQKLDTAASDGED-VEMESLFS 327
+ + G+ W RR + PA H + + +F +T+ + K S+G ++M S
Sbjct: 137 LVSAGDKWSRHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWKRLISEGSSRLDMFEHVS 196
Query: 328 RLTLDVIGKAVFNYDFDSLSNDTGIIEAVYTVLREAEDRSISPIPVWDLPIWKDISPRQR 387
+TLD + K VF++D + + I A+ + R P+ DL +++P
Sbjct: 197 LMTLDSLQKCVFSFDSNCQEKSSEYIAAILELSALVAKRHQQPLLFMDLLY--NLTPDGM 254
Query: 388 KVTAALKLVNDTLNNLIAICKRMVDEEEL-QFHEEYMNEQDPSILHFLLAS----GDDVT 442
+ A LV++ + +I +R + ++ L +F + + + LL + G +++
Sbjct: 255 RFHKACNLVHEFTDAVIRERRRTLPDQGLDEFLKSKAKSKTLDFIDVLLLTKDEDGKELS 314
Query: 443 SKQLRDDLMTMLIAGHETSAAVLTWTFYLLSKEPSVMSKLQEEVDSVLGDRFP---TIED 499
+ +R + T + GH+T+A+ L+W Y L+ +P + ++EV +L DR P +D
Sbjct: 315 DEDIRAEADTFMFEGHDTTASGLSWILYNLANDPEYQERCRQEVQELLRDRDPEEIEWDD 374
Query: 500 MKKLKYTTRVINESLRLYPQPPVLIRRSIEDDVLGE-YPIKRGEDIFISVWNLHRSPTLW 558
+ +L + T I ESLRL+P V+ R +D +L + I +G IS++ +H +P++W
Sbjct: 375 LAQLPFLTMCIKESLRLHPPVTVISRCCTQDILLPDGRTIPKGIICLISIFGIHHNPSVW 434
Query: 559 NDADKLN 565
D + N
Sbjct: 435 PDPEVYN 441
>CYPD_BACSU (O08394) Probable bifunctional P-450:NADPH-P450
reductase 1 [Includes: Cytochrome P450 102 (EC
1.14.14.1); NADPH--cytochrome P450 reductase (EC
1.6.2.4)]
Length = 1061
Score = 119 bits (298), Expect = 2e-26
Identities = 105/383 (27%), Positives = 181/383 (46%), Gaps = 25/383 (6%)
Query: 190 PKIPEAKGSISAIRSEAFFIPLYELYITYGGIFRLNFGPKSFLIVSDPAIAKHILKDNSK 249
PK G++ I + + L +L G IF+++ + ++VS + K + +
Sbjct: 10 PKTFGPLGNLPLIDKDKPTLSLIKLAEEQGPIFQIHTPAGTTIVVSGHELVKEVCDEERF 69
Query: 250 AYS-KGILAEILDFVMGKGLIPA--DGEIWRVRRRTIVPALHLKFVAAMIGLFGQATDRL 306
S +G L ++ F G GL + WR ++P + AM + D
Sbjct: 70 DKSIEGALEKVRAF-SGDGLFTSWTHEPNWRKAHNILMPTFSQR---AMKDYHEKMVDIA 125
Query: 307 CQKLDTAA--SDGEDVEMESLFSRLTLDVIGKAVFNYDFDSLSNDTG--IIEAVYTVLRE 362
Q + A + E V++ +RLTLD IG FNY F+S +T I ++ L E
Sbjct: 126 VQLIQKWARLNPNEAVDVPGDMTRLTLDTIGLCGFNYRFNSYYRETPHPFINSMVRALDE 185
Query: 363 AEDRSISPIPVWDLPIWKDISPRQRKVTAALKLVNDTLNNLIAICKRMVDEEELQFHEEY 422
A + + + V D K + +R+ ++ + ++++IA + D++E
Sbjct: 186 AMHQ-MQRLDVQD----KLMVRTKRQFRYDIQTMFSLVDSIIAERRANGDQDEKDLLARM 240
Query: 423 MNEQDPSILHFLLASGDDVTSKQLRDDLMTMLIAGHETSAAVLTWTFYLLSKEPSVMSKL 482
+N +DP +G+ + + +R ++T LIAGHET++ +L++ Y L K P + K
Sbjct: 241 LNVEDPE-------TGEKLDDENIRFQIITFLIAGHETTSGLLSFATYFLLKHPDKLKKA 293
Query: 483 QEEVDSVLGDRFPTIEDMKKLKYTTRVINESLRLYPQPPVLIRRSIEDDVL-GEYPIKRG 541
EEVD VL D PT + + +L Y ++NESLRL+P P ED V+ G++PI
Sbjct: 294 YEEVDRVLTDAAPTYKQVLELTYIRMILNESLRLWPTAPAFSLYPKEDTVIGGKFPITTN 353
Query: 542 EDIFISVWNLHRSPTLW-NDADK 563
+ I + + LHR W DA++
Sbjct: 354 DRISVLIPQLHRDRDAWGKDAEE 376
>C941_VICSA (O81117) Cytochrome P450 94A1 (EC 1.14.-.-)
(P450-dependent fatty acid omega-hydroxylase)
Length = 514
Score = 117 bits (294), Expect = 6e-26
Identities = 82/340 (24%), Positives = 161/340 (47%), Gaps = 20/340 (5%)
Query: 229 KSFLIVSDPAIAKHILKDNSKAYSKGI-LAEILDFVMGKGLIPADGEIWRVRRRTIVPAL 287
K +I +P+ +HILK+ Y KG L +G G+ +G W+ +R+
Sbjct: 91 KRQIITGNPSTVQHILKNQFSNYQKGTTFTNTLSDFLGTGIFNTNGPNWKFQRQVASHEF 150
Query: 288 HLKFVAAMIG--LFGQATDRLCQKLDTAASDGEDVEMESLFSRLTLDVIGKAVFNYDFDS 345
+ K + + + + T+RL L ++ ++ + + R T D I F YD +
Sbjct: 151 NTKSIRNFVEHIVDTELTNRLIPILTSSTQTNNILDFQDILQRFTFDNICNIAFGYDPEY 210
Query: 346 LSNDTG---IIEAVYTVLREAEDRSISPIPV-WDLPIWKDISPRQRKVTAALKLVNDTLN 401
L+ T EA + R P+P+ W + + +I +R + + +
Sbjct: 211 LTPSTNRSKFAEAYEDATEISSKRFRLPLPIIWKIKKYFNIGSEKR--------LKEAVT 262
Query: 402 NLIAICKRMVDEEELQFHEEYMNEQDPSILHFLLASGDDVTSKQLRDDLMTMLIAGHETS 461
+ + K++V E++ + E+ E + + FL + D + D +++ ++AG +T+
Sbjct: 263 EVRSFAKKLVREKKRELEEKSSLETEDMLSRFLSSGHSD--EDFVADIVISFILAGKDTT 320
Query: 462 AAVLTWTFYLLSKEPSVMSKLQEEVDSVLGDRFPTIEDMKKLKYTTRVINESLRLYPQPP 521
+A LTW F+LL K P V ++ E+ +++K++ YT ++ES+RLYP P
Sbjct: 321 SAALTWFFWLLWKNPRVEEEIVNELSK--KSELMVYDEVKEMVYTHAALSESMRLYPPVP 378
Query: 522 VLIRRSIEDDVLGE-YPIKRGEDIFISVWNLHRSPTLWND 560
+ + ++ DDVL + + +K+G + V+ + R +LW D
Sbjct: 379 MDSKEAVNDDVLPDGWVVKKGTIVTYHVYAMGRMKSLWGD 418
>CPFE_MOUSE (Q9EP75) Cytochrome P450 4F14 (EC 1.14.13.30)
(Leukotriene-B4 omega-hydroxylase) (Leukotriene-B4
20-monooxygenase) (Cytochrome P450-LTB-omega) (Cyp4f-14)
Length = 524
Score = 117 bits (293), Expect = 8e-26
Identities = 94/364 (25%), Positives = 173/364 (46%), Gaps = 14/364 (3%)
Query: 211 LYELYITYGGIFRLNFGPKSFLI-VSDPAIAKHILKDNSKAYSKGILA-EILDFVMGKGL 268
L L TY F + GP +I + I + IL ++ K ++ IL +G GL
Sbjct: 77 LTRLVGTYPQGFLMWIGPMVPVITLCHSDIVRSILNASAAVALKDVIFYSILKPWLGDGL 136
Query: 269 IPADGEIWRVRRRTIVPALHLKFVAAMIGLFGQATDRLCQKLDTAASDGED-VEMESLFS 327
+ + G+ W RR + PA H + + +F +T+ + K SDG ++M S
Sbjct: 137 LVSAGDKWSRHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWQRLISDGSARLDMFEHVS 196
Query: 328 RLTLDVIGKAVFNYDFDSLSNDTGIIEAVYTVLREAEDRSISPIPVWDLPIWKDISPRQR 387
+TLD + K VF++D + + I A+ + R P+ DL +++P
Sbjct: 197 LMTLDSLQKCVFSFDSNCQEKSSEYIAAILELSALVAKRHQQPLMFMDLLY--NLTPDGM 254
Query: 388 KVTAALKLVNDTLNNLIAICKRMVDEEELQ-FHEEYMNEQDPSILHFLLAS----GDDVT 442
+ A +V++ + +I R + ++ L F + + + LL S G +++
Sbjct: 255 RFRKACNVVHEFTDAVIRERHRTLPDQGLDDFLKSKAKSKTLDFIDVLLLSKDEDGKELS 314
Query: 443 SKQLRDDLMTMLIAGHETSAAVLTWTFYLLSKEPSVMSKLQEEVDSVLGDRFP---TIED 499
+ +R + T + GH+T+A+ L+W Y L++ P + ++EV +L R P +D
Sbjct: 315 DEDIRAEADTFMFEGHDTTASGLSWILYNLARHPEYQERCRQEVQELLRGREPEEIEWDD 374
Query: 500 MKKLKYTTRVINESLRLYPQPPVLIRRSIEDDVLGE-YPIKRGEDIFISVWNLHRSPTLW 558
+ +L + T I ESLRL+P V+ R +D +L + I +G IS++ +H +P++W
Sbjct: 375 LAQLPFLTMCIKESLRLHPPVTVISRCCTQDILLPDGRTIPKGIICLISIFGIHHNPSVW 434
Query: 559 NDAD 562
D +
Sbjct: 435 PDPE 438
>CPF3_HUMAN (Q08477) Cytochrome P450 4F3 (EC 1.14.13.30) (CYPIVF3)
(Leukotriene-B(4) omega-hydroxylase) (Leukotriene-B(4)
20-monooxygenase) (Cytochrome P450-LTB-omega)
Length = 520
Score = 117 bits (292), Expect = 1e-25
Identities = 83/309 (26%), Positives = 151/309 (48%), Gaps = 12/309 (3%)
Query: 264 MGKGLIPADGEIWRVRRRTIVPALHLKFVAAMIGLFGQATDRLCQKLDTAASDGED-VEM 322
+G GL+ + GE W RR + PA H + + +F ++ + + K AS+G ++M
Sbjct: 132 LGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDM 191
Query: 323 ESLFSRLTLDVIGKAVFNYDFDSLSNDTGIIEAVYTVLREAEDRSISPIPVWDLPIWKDI 382
S +TLD + K VF++D + I A+ + R + D + +
Sbjct: 192 FEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQILLYIDFLYY--L 249
Query: 383 SPRQRKVTAALKLVNDTLNNLIAICKRMVDEEELQ-FHEEYMNEQDPSILHFLLASGDD- 440
+P ++ A +LV+D +++I +R + + + F + + + LL S D+
Sbjct: 250 TPDGQRFRRACRLVHDFTDDVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDED 309
Query: 441 ---VTSKQLRDDLMTMLIAGHETSAAVLTWTFYLLSKEPSVMSKLQEEVDSVLGDRFP-- 495
++ + +R + T + GH+T+A+ L+W Y L+K P + ++EV +L DR P
Sbjct: 310 GKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKE 369
Query: 496 -TIEDMKKLKYTTRVINESLRLYPQPPVLIRRSIEDDVLGE-YPIKRGEDIFISVWNLHR 553
+D+ +L + T I ESLRL+P P + R +D VL + I +G ISV+ H
Sbjct: 370 IEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHH 429
Query: 554 SPTLWNDAD 562
+P +W D +
Sbjct: 430 NPAVWPDPE 438
>CPF8_HUMAN (P98187) Cytochrome P450 4F8 (EC 1.14.14.1) (CYPIVF8)
Length = 520
Score = 116 bits (290), Expect = 2e-25
Identities = 91/364 (25%), Positives = 175/364 (48%), Gaps = 14/364 (3%)
Query: 211 LYELYITYGGIFRLNFGPKSFLI-VSDPAIAKHILKDNSKAYSKGILA-EILDFVMGKGL 268
L +L TY F GP + +I + P I + ++ + K I+ + L +G GL
Sbjct: 77 LTQLVATYPQGFVRWLGPITPIINLCHPDIVRSVINTSDAITDKDIVFYKTLKPWLGDGL 136
Query: 269 IPADGEIWRVRRRTIVPALHLKFVAAMIGLFGQATDRLCQKLDTAASDGED-VEMESLFS 327
+ + G+ WR RR + PA H + I +F ++ + + K A +G +++ S
Sbjct: 137 LLSVGDKWRHHRRLLTPAFHFNILKPYIKIFSKSANIMHAKWQRLAMEGSTCLDVFEHIS 196
Query: 328 RLTLDVIGKAVFNYDFDSLSNDTGIIEAVYTVLREAEDRSISPIPVWDLPIWKDISPRQR 387
+TLD + K +F++D + + I A+ + R+ D + ++P R
Sbjct: 197 LMTLDSLQKCIFSFDSNCQEKPSEYITAIMELSALVVKRNNQFFRYKDFLYF--LTPCGR 254
Query: 388 KVTAALKLVNDTLNNLIAICKRMVDEEELQ-FHEEYMNEQDPSILHFLLAS----GDDVT 442
+ A +LV+D + +I +R + + + F + + + LL S G +++
Sbjct: 255 RFHRACRLVHDFTDAVIQERRRTLTSQGVDDFLQAKAKSKTLDFIDVLLLSEDKNGKELS 314
Query: 443 SKQLRDDLMTMLIAGHETSAAVLTWTFYLLSKEPSVMSKLQEEVDSVLGDRFP---TIED 499
+ +R + T + GH+T+A+ L+W Y L++ P + ++EV +L DR P +D
Sbjct: 315 DEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDREPKEIEWDD 374
Query: 500 MKKLKYTTRVINESLRLYPQPPVLIRRSIEDDVLGE-YPIKRGEDIFISVWNLHRSPTLW 558
+ +L + T + ESLRL+P P R +D VL + I +G I+++ +H +P++W
Sbjct: 375 LAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLPDSRVIPKGNVCNINIFAIHHNPSVW 434
Query: 559 NDAD 562
D +
Sbjct: 435 PDPE 438
>C4AE_DROME (O46054) Cytochrome P450 4ae1 (EC 1.14.-.-) (CYPIVAE1)
Length = 496
Score = 115 bits (288), Expect = 3e-25
Identities = 88/340 (25%), Positives = 152/340 (43%), Gaps = 20/340 (5%)
Query: 233 IVSDPAIAKHI--LKDNSKAYSKGILAEILDFVMGKGLIPADGEIWRVRRRTIVPALHLK 290
+V A +HI L KG + L +G GL+ + G+ W R+ I P H
Sbjct: 80 VVMVTAEPRHIDALLQGQHQLKKGTMYFALRGWLGDGLLLSRGKEWHTMRKIITPTFHFS 139
Query: 291 FVAAMIGLFGQATDRLCQKLDTAASDGEDVEMESLFSRLTLDVIGKAVFNYDFDSLSNDT 350
+ + +F + + L ++L T + E V + L LD+I + + D+ D+
Sbjct: 140 ILEQFVEVFDRQSSILVERLRTLSYGNEVVNIYPLVGLAALDIITETAMGVNVDAQGADS 199
Query: 351 GIIEAVYTVLREAEDRSISPIPVWDLPIWKDISPRQRKVTAALKLVNDTLNNLIAICKRM 410
++ AV + R + P ++ RK A + +++ N +I +R+
Sbjct: 200 EVVHAVKDLTNILATRFMRPHLLFPHLFRLCWPSGFRKQQAGVICLHEFTNGIIEQRRRL 259
Query: 411 VDEEELQFHEEYMNEQDPSILHFLL-------ASGDDVTSKQLRDDLMTMLIAGHETSAA 463
+ E N+ P+ H LL G +T KQ+RD++ T + GH+T+ +
Sbjct: 260 LARE--------ANQDKPTKPHALLDTLLRATVDGQPLTDKQIRDEVNTFIFEGHDTTTS 311
Query: 464 VLTWTFYLLSKEPSVMSKLQEEVDSVLGD---RFPTIEDMKKLKYTTRVINESLRLYPQP 520
+++ YLLS+ +V KL EE+ G R + D L Y + V+ ESLRLYP
Sbjct: 312 AVSFCLYLLSRHEAVQQKLFEELRMHYGQDLFRGVILSDFATLPYLSCVVKESLRLYPPI 371
Query: 521 PVLIRRSIEDDVLGEYPIKRGEDIFISVWNLHRSPTLWND 560
P + R +D V+ E I G ++ + +W L R ++ D
Sbjct: 372 PAVARCLEKDLVIDEGYIPVGTNVVVLLWQLLRDEAIFTD 411
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.319 0.136 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,858,995
Number of Sequences: 164201
Number of extensions: 2858490
Number of successful extensions: 9060
Number of sequences better than 10.0: 658
Number of HSP's better than 10.0 without gapping: 560
Number of HSP's successfully gapped in prelim test: 98
Number of HSP's that attempted gapping in prelim test: 7370
Number of HSP's gapped (non-prelim): 867
length of query: 569
length of database: 59,974,054
effective HSP length: 116
effective length of query: 453
effective length of database: 40,926,738
effective search space: 18539812314
effective search space used: 18539812314
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Medicago: description of AC148994.8