BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC148970.12 + phase: 0
(560 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
SYK_ARATH (Q9ZPI1) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--t... 850 0.0
SYK_ORYSA (Q6F2U9) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--t... 838 0.0
SYK_LYCES (Q43776) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--t... 729 0.0
SYK_MOUSE (Q99MN1) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--t... 656 0.0
SYK_CRILO (P37879) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--t... 654 0.0
SYK_HUMAN (Q15046) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--t... 645 0.0
SYK_CAEEL (Q22099) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--t... 597 e-170
SYKC_YEAST (P15180) Lysyl-tRNA synthetase, cytoplasmic (EC 6.1.1... 560 e-159
SYK_THEMA (Q9X231) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--t... 402 e-112
SYK_CLOTE (Q899G7) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--t... 400 e-111
SYK_CHLTE (Q8KCM7) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--t... 391 e-108
SYK_LEPIN (Q8F4P5) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--t... 388 e-107
SYK_THETN (Q8R7N1) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--t... 386 e-107
SYK_AQUAE (O67258) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--t... 385 e-106
SYK_CLOAB (Q97EB7) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--t... 380 e-105
SYK2_METMA (Q8PVP6) Lysyl-tRNA synthetase 2 (EC 6.1.1.6) (Lysine... 380 e-105
SYK_BACHD (Q9KGG4) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--t... 377 e-104
SYK2_METAC (Q8TSN5) Lysyl-tRNA synthetase 2 (EC 6.1.1.6) (Lysine... 377 e-104
SYK_BACSU (P37477) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--t... 375 e-103
SYK_PORGI (Q7MUV7) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--t... 375 e-103
>SYK_ARATH (Q9ZPI1) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA
ligase) (LysRS)
Length = 626
Score = 850 bits (2197), Expect = 0.0
Identities = 411/539 (76%), Positives = 468/539 (86%), Gaps = 1/539 (0%)
Query: 4 AQENRPAAADEEDMDPTQYLENRLKYLSTEKEEGRNPYPHKFSATMTIKQYIKEYEGLSD 63
A + AAD+E+MD TQY ENRLKYL+ EK +G NPYPHKF+ +M+I +YI+ Y L++
Sbjct: 72 ASSQKAVAADDEEMDATQYYENRLKYLAAEKAKGENPYPHKFAVSMSIPKYIETYGSLNN 131
Query: 64 GQHLDDVSVSLTGKIMHKRSSGAKLVFYDLHDDGFKVQVMADASKSDLNEAGFDKVHSNV 123
G H+++ SL G+IM KRSS +KL FYDLH D FKVQVMADASKS L+EA F K+HSN
Sbjct: 132 GDHVENAEESLAGRIMSKRSSSSKLFFYDLHGDDFKVQVMADASKSGLDEAEFLKLHSNA 191
Query: 124 KRGDIVGITGFPGKSRKGELSIFPKTFVVLSHCLHMMPRQKSAAAAAADNAWLPGKTRNP 183
KRGDIVG+ GFPGK+++GELSIFP++F++LSHCLHMMPR+ A W+PG+TRNP
Sbjct: 192 KRGDIVGVIGFPGKTKRGELSIFPRSFILLSHCLHMMPRKADNVNAKKPEIWVPGQTRNP 251
Query: 184 EAYTLKDQETRYRLRHLDLMLNTEVREIFRTRSKIISYVRSFLDKLDFLEVETPMMNMIA 243
EAY LKDQE+RYR RHLD++LN EVR+IFRTR+KIISYVR FLD +FLEVETPMMNMIA
Sbjct: 252 EAYVLKDQESRYRQRHLDMILNVEVRQIFRTRAKIISYVRRFLDNKNFLEVETPMMNMIA 311
Query: 244 GGAAARPFVTHHNDLNMRLFMRIAPELYLKKLVVGGLNRVYEIGKQFRNEGIDLTHNPEF 303
GGAAARPFVTHHNDL+MRL+MRIAPELYLK+L+VGGL RVYEIGKQFRNEGIDLTHNPEF
Sbjct: 312 GGAAARPFVTHHNDLDMRLYMRIAPELYLKQLIVGGLERVYEIGKQFRNEGIDLTHNPEF 371
Query: 304 TTCEFYMAYKDYYDLMEITENMLSGMVYELTKGSYKIKYHADGLDKDPIEIDFTPPFRRI 363
TTCEFYMA+ DY DLME+TE MLSGMV ELT G YKIKY+A+G DKDPIEIDFTPPFRRI
Sbjct: 372 TTCEFYMAFADYNDLMEMTEVMLSGMVKELT-GGYKIKYNANGYDKDPIEIDFTPPFRRI 430
Query: 364 DMIEGLEEMAGLSIPKDLTSAEANQYLRDACLKYEIKCPPPETTARLLDKLVGHFLEETC 423
+MI LE++A L+IPKDL S EAN+YL DAC ++++KCPPP+TTARLLDKLVG FLE TC
Sbjct: 431 EMIGELEKVAKLNIPKDLASEEANKYLIDACARFDVKCPPPQTTARLLDKLVGEFLEPTC 490
Query: 424 VNPTFIINHPEIMSPLAKWHRTKPGLTERFELFINKHELANAYTELNDPVVQRQRFADQL 483
VNPTFIIN PEIMSPLAKWHR+K GLTERFELFINKHEL NAYTELNDPVVQRQRFADQL
Sbjct: 491 VNPTFIINQPEIMSPLAKWHRSKSGLTERFELFINKHELCNAYTELNDPVVQRQRFADQL 550
Query: 484 KDRQSGDDEAMALDETFCTALEYGLPPTAGWGLGIDRLTMLLTDSQNIKEVLLFPAMKP 542
KDRQSGDDEAMALDETFC ALEYGL PT GWGLGIDRL+MLLTDS NIKEVL FPAM+P
Sbjct: 551 KDRQSGDDEAMALDETFCNALEYGLAPTGGWGLGIDRLSMLLTDSLNIKEVLFFPAMRP 609
>SYK_ORYSA (Q6F2U9) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA
ligase) (LysRS)
Length = 602
Score = 838 bits (2166), Expect = 0.0
Identities = 409/542 (75%), Positives = 465/542 (85%), Gaps = 2/542 (0%)
Query: 3 SAQENRPAAADEEDMDPTQYLENRLKYLSTEKEEGRNPYPHKFSATMTIKQYIKEYEGLS 62
S + + +AAD+E+MDPTQY ENRLK L + K G NPYPHKF A +T+ YI++Y+ ++
Sbjct: 63 SGEPPKESAADDEEMDPTQYYENRLKALDSLKATGVNPYPHKFLANITVADYIEKYKSMN 122
Query: 63 DGQHLDDVSVSLTGKIMHKRSSGAKLVFYDLHDDGFKVQVMADASKSDLNEAGFDKVHSN 122
G L DV+ L G+IM KR+ +KL+FYDL+ G KVQV ADA S+L + F K HS
Sbjct: 123 VGDKLVDVTECLAGRIMTKRAQSSKLLFYDLYGGGEKVQVFADARTSELEDNEFIKFHST 182
Query: 123 VKRGDIVGITGFPGKSRKGELSIFPKTFVVLSHCLHMMPRQKSAAAAAADNAWLPGKTRN 182
+KRGDIVG+ G+PGKS++GELSIFPK VVLS CLHMMPRQKS +A W PG RN
Sbjct: 183 LKRGDIVGVCGYPGKSKRGELSIFPKKIVVLSPCLHMMPRQKSEGSAVP-TPWAPGMGRN 241
Query: 183 PEAYTLKDQETRYRLRHLDLMLNTEVREIFRTRSKIISYVRSFLDKLDFLEVETPMMNMI 242
E Y L+DQETRYR R+LDLM+N EVR IF+TRSK++S++R FLD LDFLEVETPMMNMI
Sbjct: 242 IEKYVLRDQETRYRQRYLDLMVNHEVRHIFKTRSKVVSFIRKFLDGLDFLEVETPMMNMI 301
Query: 243 AGGAAARPFVTHHNDLNMRLFMRIAPELYLKKLVVGGLNRVYEIGKQFRNEGIDLTHNPE 302
AGGAAARPFVTHHN+LNMRL+MRIAPELYLK+LVVGGL+RVYEIGKQFRNEGIDLTHNPE
Sbjct: 302 AGGAAARPFVTHHNELNMRLYMRIAPELYLKELVVGGLDRVYEIGKQFRNEGIDLTHNPE 361
Query: 303 FTTCEFYMAYKDYYDLMEITENMLSGMVYELTKGSYKIKYHADGLDKDPIEIDFTPPFRR 362
FTTCEFYMAY DY DL+E+TE MLSGMV ELT G YKIKYHA+G++K PIEIDFTPPFR+
Sbjct: 362 FTTCEFYMAYADYNDLIELTETMLSGMVKELT-GGYKIKYHANGVEKPPIEIDFTPPFRK 420
Query: 363 IDMIEGLEEMAGLSIPKDLTSAEANQYLRDACLKYEIKCPPPETTARLLDKLVGHFLEET 422
IDMIE LE MA L+IPKDL+S EAN+YL DAC KY++KCPPP+TT RLLDKLVGHFLEET
Sbjct: 421 IDMIEELEAMAKLNIPKDLSSDEANKYLIDACAKYDVKCPPPQTTTRLLDKLVGHFLEET 480
Query: 423 CVNPTFIINHPEIMSPLAKWHRTKPGLTERFELFINKHELANAYTELNDPVVQRQRFADQ 482
CVNPTFIINHPEIMSPLAKWHR++PGLTERFELF+NKHE+ NAYTELNDPVVQRQRF +Q
Sbjct: 481 CVNPTFIINHPEIMSPLAKWHRSRPGLTERFELFVNKHEVCNAYTELNDPVVQRQRFEEQ 540
Query: 483 LKDRQSGDDEAMALDETFCTALEYGLPPTAGWGLGIDRLTMLLTDSQNIKEVLLFPAMKP 542
LKDRQSGDDEAMALDETFCTALEYGLPPT GWGLGIDRLTMLLTDSQNIKEVLLFPAMKP
Sbjct: 541 LKDRQSGDDEAMALDETFCTALEYGLPPTGGWGLGIDRLTMLLTDSQNIKEVLLFPAMKP 600
Query: 543 QD 544
QD
Sbjct: 601 QD 602
>SYK_LYCES (Q43776) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA
ligase) (LysRS)
Length = 588
Score = 729 bits (1883), Expect = 0.0
Identities = 347/550 (63%), Positives = 439/550 (79%), Gaps = 15/550 (2%)
Query: 5 QENRPAAADEEDMDPTQYLENRLKYLSTEKEEGRNPYPHKFSATMTIKQYIKEYEGLSDG 64
Q N P + +D+DPTQYL NRL+ + + +E G NPYPHKF TM+I ++I Y L+ G
Sbjct: 43 QHNLP---ENDDLDPTQYLANRLRNIESLRESGINPYPHKFFITMSIPEFISRYAHLNTG 99
Query: 65 QHLDDVSVSLTGKIMHKRSSGAKLVFYDLHDDGFKVQVMADASKSDLNEAGFDKVHSNVK 124
+ +D+ +SL G+++ KR+S +KL FY+L G +VQV+A A SD++ F S VK
Sbjct: 100 EFPEDIDMSLAGRVISKRASSSKLYFYELLGGGARVQVLASARDSDVDAVQFSNYQSGVK 159
Query: 125 RGDIVGITGFPGKSRKGELSIFPKTFVVLSHCLHMMPRQKSAAAA-----------AADN 173
RGDI+G+ G+PGKS++GELSIF K F+VL+ CLHM+PR+ +++ A +
Sbjct: 160 RGDIIGVRGYPGKSKRGELSIFAKPFIVLAPCLHMLPRRLTSSIVDETRTQNFQGITAYD 219
Query: 174 AWLPGKTRNPEAYTLKDQETRYRLRHLDLMLNTEVREIFRTRSKIISYVRSFLDKLDFLE 233
W PG RNPE+Y L+DQETRYR R+LDLM+N EVR +FRTR++IISY+RSFLD L+FLE
Sbjct: 220 TWTPGDLRNPESYVLRDQETRYRQRYLDLMMNPEVRALFRTRARIISYIRSFLDNLEFLE 279
Query: 234 VETPMMNMIAGGAAARPFVTHHNDLNMRLFMRIAPELYLKKLVVGGLNRVYEIGKQFRNE 293
VETP MN+ AGGA+ARPF+THHN+L+ L +R++PELYLKKLVVGG +RVYE+GK FRNE
Sbjct: 280 VETPSMNLTAGGASARPFITHHNELDTELLIRVSPELYLKKLVVGGFDRVYELGKHFRNE 339
Query: 294 GIDLTHNPEFTTCEFYMAYKDYYDLMEITENMLSGMVYELTKGSYKIKYHADGLDKDPIE 353
G+DLTH+PEFT CE YMAY DY DLM++TE +LSGMV +LT GSYKI+YHA+GLD +PIE
Sbjct: 340 GMDLTHSPEFTMCELYMAYADYNDLMDLTEQLLSGMVKDLT-GSYKIRYHANGLDNEPIE 398
Query: 354 IDFTPPFRRIDMIEGLEEMAGLSIPKDLTSAEANQYLRDACLKYEIKCPPPETTARLLDK 413
IDFTPPFR+IDM+ LE++A +SIP+DL+S AN++L D C K+++KCPPP TT RLLDK
Sbjct: 399 IDFTPPFRKIDMLSELEKVANISIPRDLSSESANKHLVDVCEKFDVKCPPPHTTTRLLDK 458
Query: 414 LVGHFLEETCVNPTFIINHPEIMSPLAKWHRTKPGLTERFELFINKHELANAYTELNDPV 473
LVGHF+E C+NPTFIINHPEIMSPLAK R++PGLTERF LF+N+ EL +AYTELNDP
Sbjct: 459 LVGHFIEVNCINPTFIINHPEIMSPLAKSRRSEPGLTERFNLFVNRRELCDAYTELNDPT 518
Query: 474 VQRQRFADQLKDRQSGDDEAMALDETFCTALEYGLPPTAGWGLGIDRLTMLLTDSQNIKE 533
QR+RFA+QLKDRQ GDDEAM LDE+F TALEYGLPPT G G+GIDRLTMLLTDSQN+KE
Sbjct: 519 AQRERFAEQLKDRQLGDDEAMDLDESFITALEYGLPPTGGLGMGIDRLTMLLTDSQNVKE 578
Query: 534 VLLFPAMKPQ 543
V+LFPAM+ Q
Sbjct: 579 VILFPAMRLQ 588
>SYK_MOUSE (Q99MN1) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA
ligase) (LysRS)
Length = 595
Score = 656 bits (1693), Expect = 0.0
Identities = 323/535 (60%), Positives = 404/535 (75%), Gaps = 25/535 (4%)
Query: 12 ADEEDMDPTQYLENRLKYLSTEKEEGRNPYPHKFSATMTIKQYIKEYEGLSDGQHLDDVS 71
A+EE +DP QY + R + + K G +PYPHKF +++ Q+I+EY L G HL DV+
Sbjct: 64 AEEETLDPNQYYKIRSQAVQQLKVTGEDPYPHKFHVDISLTQFIQEYSHLQPGDHLTDVT 123
Query: 72 VSLTGKIMHKRSSGAKLVFYDLHDDGFKVQVMADASKSDLNEAGFDKVHSNVKRGDIVGI 131
+ + G+I KR+SG KL+FYDL +G K+QVMA+ S++ +E F +++ ++RGDI+G+
Sbjct: 124 LKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMAN-SRNYKSEEEFVHINNKLRRGDIIGV 182
Query: 132 TGFPGKSRKGELSIFPKTFVVLSHCLHMMPRQKSAAAAAADNAWLPGKTRNPEAYTLKDQ 191
G PGK++KGELSI P+ +LS CLHM+P + LKD+
Sbjct: 183 EGNPGKTKKGELSIIPQEITLLSPCLHMLPHLH---------------------FGLKDK 221
Query: 192 ETRYRLRHLDLMLNTEVREIFRTRSKIISYVRSFLDKLDFLEVETPMMNMIAGGAAARPF 251
ETRYR R+LDL+LN VR+ F RSKII+Y+RSFLD+L FLE+ETPMMN+I GGA A+PF
Sbjct: 222 ETRYRQRYLDLILNDFVRQKFIVRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPF 281
Query: 252 VTHHNDLNMRLFMRIAPELYLKKLVVGGLNRVYEIGKQFRNEGIDLTHNPEFTTCEFYMA 311
+T+HN+L+M L+MRIAPELY K LVVGG++RVYEIG+QFRNEGIDLTHNPEFTTCEFYMA
Sbjct: 282 ITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMA 341
Query: 312 YKDYYDLMEITENMLSGMVYELTKGSYKIKYHADGLDKDPIEIDFTPPFRRIDMIEGLEE 371
Y DY+DLMEITE MLSGMV +T GSYKI YH DG + E+DFTPPFRRI M+E LE+
Sbjct: 342 YADYHDLMEITEKMLSGMVKSIT-GSYKITYHPDGPEGQAYEVDFTPPFRRISMVEELEK 400
Query: 372 MAGLSIPKD--LTSAEANQYLRDACLKYEIKCPPPETTARLLDKLVGHFLEETCVNPTFI 429
G+ +P+ + E + L D C+ ++CPPP TTARLLDKLVG FLE TC++PTFI
Sbjct: 401 ALGVKLPETSLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCISPTFI 460
Query: 430 INHPEIMSPLAKWHRTKPGLTERFELFINKHELANAYTELNDPVVQRQRFADQLKDRQSG 489
+HP+IMSPLAKWHR+K GLTERFELF+ K E+ NAYTELNDPV QRQ F +Q K + +G
Sbjct: 461 CDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPVRQRQLFEEQAKAKAAG 520
Query: 490 DDEAMALDETFCTALEYGLPPTAGWGLGIDRLTMLLTDSQNIKEVLLFPAMKPQD 544
DDEAM +DE FCTALEYGLPPTAGWG+GIDRLTM LTDS NIKEVLLFPAMKP+D
Sbjct: 521 DDEAMFIDENFCTALEYGLPPTAGWGMGIDRLTMFLTDSNNIKEVLLFPAMKPED 575
>SYK_CRILO (P37879) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA
ligase) (LysRS)
Length = 597
Score = 654 bits (1688), Expect = 0.0
Identities = 320/534 (59%), Positives = 404/534 (74%), Gaps = 25/534 (4%)
Query: 13 DEEDMDPTQYLENRLKYLSTEKEEGRNPYPHKFSATMTIKQYIKEYEGLSDGQHLDDVSV 72
+EE +DP QY + R + + K G +PYPHKF +++ Q+I+EY L G HL D+++
Sbjct: 67 EEETLDPNQYYKIRSQAIHQLKVSGEDPYPHKFHVDISLTQFIQEYSQLQPGDHLTDITL 126
Query: 73 SLTGKIMHKRSSGAKLVFYDLHDDGFKVQVMADASKSDLNEAGFDKVHSNVKRGDIVGIT 132
+ G+I KR+SG KL+FYDL +G K+QVMA+ S++ +E F ++++ ++RGDI+G+
Sbjct: 127 KVAGRIHAKRASGGKLIFYDLRGEGVKLQVMAN-SRNYKSEEEFVRINNKLRRGDIIGVQ 185
Query: 133 GFPGKSRKGELSIFPKTFVVLSHCLHMMPRQKSAAAAAADNAWLPGKTRNPEAYTLKDQE 192
G PGK++KGELSI P +LS CLHM+P + LKD+E
Sbjct: 186 GNPGKTKKGELSIIPYEITLLSPCLHMLPHLH---------------------FGLKDKE 224
Query: 193 TRYRLRHLDLMLNTEVREIFRTRSKIISYVRSFLDKLDFLEVETPMMNMIAGGAAARPFV 252
TRYR R+LDL+LN VR+ F R+KII+Y+RSFLD+L FLE+ETPMMN+I GGA A+PF+
Sbjct: 225 TRYRQRYLDLILNDFVRQKFIVRAKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFI 284
Query: 253 THHNDLNMRLFMRIAPELYLKKLVVGGLNRVYEIGKQFRNEGIDLTHNPEFTTCEFYMAY 312
T+HN+L+M L+MRIAPELY K LVVGG++RVYEIG+QFRNEGIDLTHNPEFTTCEFYMAY
Sbjct: 285 TYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAY 344
Query: 313 KDYYDLMEITENMLSGMVYELTKGSYKIKYHADGLDKDPIEIDFTPPFRRIDMIEGLEEM 372
DY+DLMEITE MLSGMV +T GSYKI YH DG + + EIDFTPPFRRI M+E LE+
Sbjct: 345 ADYHDLMEITEKMLSGMVKSIT-GSYKITYHPDGPEGEAYEIDFTPPFRRISMVEELEKA 403
Query: 373 AGLSIPKD--LTSAEANQYLRDACLKYEIKCPPPETTARLLDKLVGHFLEETCVNPTFII 430
G+ +P+ + E + L D C+ ++CPPP TTARLLDKLVG FLE TC+NPTFI
Sbjct: 404 LGVKLPETSLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFIC 463
Query: 431 NHPEIMSPLAKWHRTKPGLTERFELFINKHELANAYTELNDPVVQRQRFADQLKDRQSGD 490
+HP+IMSPLAKWHR+K GLTERFELF+ K E+ NAYTELNDP+ QRQ F +Q K + +GD
Sbjct: 464 DHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGD 523
Query: 491 DEAMALDETFCTALEYGLPPTAGWGLGIDRLTMLLTDSQNIKEVLLFPAMKPQD 544
DEAM +DE FCTALEYGLPPTAGWG+GIDR+TM LTDS NIKEVLLFPAMKP+D
Sbjct: 524 DEAMFIDENFCTALEYGLPPTAGWGMGIDRVTMFLTDSNNIKEVLLFPAMKPED 577
>SYK_HUMAN (Q15046) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA
ligase) (LysRS)
Length = 597
Score = 645 bits (1665), Expect = 0.0
Identities = 314/534 (58%), Positives = 401/534 (74%), Gaps = 25/534 (4%)
Query: 13 DEEDMDPTQYLENRLKYLSTEKEEGRNPYPHKFSATMTIKQYIKEYEGLSDGQHLDDVSV 72
+EE +DP QY + R + + K G +PYPHKF +++ +I++Y L G HL D+++
Sbjct: 67 EEESVDPNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDHLTDITL 126
Query: 73 SLTGKIMHKRSSGAKLVFYDLHDDGFKVQVMADASKSDLNEAGFDKVHSNVKRGDIVGIT 132
+ G+I KR+SG KL+FYDL +G K+QVMA+ S++ +E F +++ ++RGDI+G+
Sbjct: 127 KVAGRIHAKRASGGKLIFYDLRGEGVKLQVMAN-SRNYKSEEEFIHINNKLRRGDIIGVQ 185
Query: 133 GFPGKSRKGELSIFPKTFVVLSHCLHMMPRQKSAAAAAADNAWLPGKTRNPEAYTLKDQE 192
G PGK++KGELSI P +LS CLHM+P + LKD+E
Sbjct: 186 GNPGKTKKGELSIIPYEITLLSPCLHMLPHLH---------------------FGLKDKE 224
Query: 193 TRYRLRHLDLMLNTEVREIFRTRSKIISYVRSFLDKLDFLEVETPMMNMIAGGAAARPFV 252
TRYR R+LDL+LN VR+ F RSKII+Y+RSFLD+L FLE+ETPMMN+I GGA A+PF+
Sbjct: 225 TRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFI 284
Query: 253 THHNDLNMRLFMRIAPELYLKKLVVGGLNRVYEIGKQFRNEGIDLTHNPEFTTCEFYMAY 312
T+HN+L+M L+MRIAPELY K LVVGG++RVYEIG+QFRNEGIDLTHNPEFTTCEFYMAY
Sbjct: 285 TYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAY 344
Query: 313 KDYYDLMEITENMLSGMVYELTKGSYKIKYHADGLDKDPIEIDFTPPFRRIDMIEGLEEM 372
DY+DLMEITE M+SGMV +T GSYK+ YH DG + ++DFTPPFRRI+M+E LE+
Sbjct: 345 ADYHDLMEITEKMVSGMVKHIT-GSYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKA 403
Query: 373 AGLSIPKD--LTSAEANQYLRDACLKYEIKCPPPETTARLLDKLVGHFLEETCVNPTFII 430
G+ +P+ + E + L D C+ ++CPPP TTARLLDKLVG FLE TC+NPTFI
Sbjct: 404 LGMKLPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFIC 463
Query: 431 NHPEIMSPLAKWHRTKPGLTERFELFINKHELANAYTELNDPVVQRQRFADQLKDRQSGD 490
+HP+IMSPLAKWHR+K GLTERFELF+ K E+ NAYTELNDP+ QRQ F +Q K + +GD
Sbjct: 464 DHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGD 523
Query: 491 DEAMALDETFCTALEYGLPPTAGWGLGIDRLTMLLTDSQNIKEVLLFPAMKPQD 544
DEAM +DE FCTALEYGLPPTAGWG+GIDR+ M LTDS NIKEVLLFPAMKP+D
Sbjct: 524 DEAMFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPAMKPED 577
>SYK_CAEEL (Q22099) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA
ligase) (LysRS)
Length = 572
Score = 597 bits (1540), Expect = e-170
Identities = 293/545 (53%), Positives = 388/545 (70%), Gaps = 28/545 (5%)
Query: 4 AQENRPAAADEED-MDPTQYLENRLKYLSTEKEEGRNPYPHKFSATMTIKQYIKEYEGLS 62
A + P E D DP +Y R++ + + G NP+PHKF+ T+++ +I +Y L
Sbjct: 37 AVADAPKVVREADPSDPQEYFNMRVRMIEARRAAGDNPFPHKFNVTISLTDFITKYTPLE 96
Query: 63 DGQHLDDVSVSLTGKIMHKRSSGAKLVFYDLHDDGFKVQVMADASKSDLNEAGFDKVHSN 122
Q ++++ VS+ G+I KR SG+KLVFYD+H +G +Q+MA+A K + F +H
Sbjct: 97 KEQVVEEI-VSVAGRIHSKRESGSKLVFYDIHGEGTHIQIMANA-KFHTGDVDFVTLHDR 154
Query: 123 VKRGDIVGITGFPGKSRKGELSIFPKTFVVLSHCLHMMPRQKSAAAAAADNAWLPGKTRN 182
+KRGDIVG TG +++ GELS+ P + L+ CLHM+P
Sbjct: 155 IKRGDIVGFTGRATRTKAGELSLIPNEILQLTPCLHMLPHSH------------------ 196
Query: 183 PEAYTLKDQETRYRLRHLDLMLNTEVREIFRTRSKIISYVRSFLDKLDFLEVETPMMNMI 242
+ LKD+E R+R R+LDL+LN V++ F RSKII+++R +LD L FLEVETP+MN I
Sbjct: 197 ---FGLKDKELRFRKRYLDLILNPRVKDNFVIRSKIITFLRRYLDNLGFLEVETPIMNQI 253
Query: 243 AGGAAARPFVTHHNDLNMRLFMRIAPELYLKKLVVGGLNRVYEIGKQFRNEGIDLTHNPE 302
AGGA A+PF+THHNDL+M LF+R+APELY K LVVGG++RVYE+G+ FRNEGIDLTHNPE
Sbjct: 254 AGGATAKPFITHHNDLDMNLFLRVAPELYHKMLVVGGIDRVYEVGRLFRNEGIDLTHNPE 313
Query: 303 FTTCEFYMAYKDYYDLMEITENMLSGMVYELTKGSYKIKYHADGLDKDPI-EIDFTPPFR 361
FTTCEFYMAY DY D++++TE++LS MV + KG+YKI+YH +G + +P+ E+DFTPPF+
Sbjct: 314 FTTCEFYMAYADYEDVIQLTEDLLSSMVMSI-KGTYKIEYHPNGPNTEPVYEVDFTPPFK 372
Query: 362 RIDMIEGLEEMAGLSIPKDLT--SAEANQYLRDACLKYEIKCPPPETTARLLDKLVGHFL 419
R+ M +GL E G ++P T + EA + C + C P TTARLLDKLVG +L
Sbjct: 373 RVHMYDGLAEKLGATLPDPSTLHTEEAREVFDKLCRDNNVDCSAPRTTARLLDKLVGEYL 432
Query: 420 EETCVNPTFIINHPEIMSPLAKWHRTKPGLTERFELFINKHELANAYTELNDPVVQRQRF 479
E T ++PTF+I HP+IMSPLAKWHR+ PGLTERFELF E+ANAYTELNDP+ QRQRF
Sbjct: 433 ESTFISPTFLIGHPQIMSPLAKWHRSIPGLTERFELFAVTREIANAYTELNDPITQRQRF 492
Query: 480 ADQLKDRQSGDDEAMALDETFCTALEYGLPPTAGWGLGIDRLTMLLTDSQNIKEVLLFPA 539
Q KD+ +GDDEA +DETFC ALEYGLPPT GWG+GIDRL+M+LTD+ NIKEVLLFPA
Sbjct: 493 EQQAKDKDAGDDEAQMIDETFCNALEYGLPPTGGWGMGIDRLSMILTDNNNIKEVLLFPA 552
Query: 540 MKPQD 544
M+P+D
Sbjct: 553 MRPED 557
>SYKC_YEAST (P15180) Lysyl-tRNA synthetase, cytoplasmic (EC 6.1.1.6)
(Lysine--tRNA ligase) (LysRS)
Length = 590
Score = 560 bits (1444), Expect = e-159
Identities = 288/554 (51%), Positives = 387/554 (68%), Gaps = 37/554 (6%)
Query: 2 RSAQENRPAAADEEDM----DPTQYLENRLKYLST-EKEEGRNPYPHKFSATMTIKQYIK 56
++A + +PA+ + D+ DP+QY E R + + K NPYPHKF +++ +++
Sbjct: 48 KAAAQPKPASKKKTDLFADLDPSQYFETRSRQIQELRKTHEPNPYPHKFHVSISNPEFLA 107
Query: 57 EYEGLSDGQHLDDVSVSLTGKIMHKRSSGAKLVFYDLHDDGFKVQVMADASKSDLNEAGF 116
+Y L G+ L + VS+ G+I KR SG+KL FY LH DG +VQ+M+ + + +
Sbjct: 108 KYAHLKKGETLPEEKVSIAGRIHAKRESGSKLKFYVLHGDGVEVQLMSQL-QDYCDPDSY 166
Query: 117 DKVHSNVKRGDIVGITGFPGKSR-----KGELSIFPKTFVVLSHCLHMMPRQKSAAAAAA 171
+K H +KRGDIVG+ G+ G+++ +GE+S+F +L+ CLHM+P A
Sbjct: 167 EKDHDLLKRGDIVGVEGYVGRTQPKKGGEGEVSVFVSRVQLLTPCLHMLP---------A 217
Query: 172 DNAWLPGKTRNPEAYTLKDQETRYRLRHLDLMLNTEVREIFRTRSKIISYVRSFLDKLDF 231
D+ + KDQETRYR R+LDL++N + R F TRS+II Y+R FLD+ F
Sbjct: 218 DH------------FGFKDQETRYRKRYLDLIMNKDARNRFITRSEIIRYIRRFLDQRKF 265
Query: 232 LEVETPMMNMIAGGAAARPFVTHHNDLNMRLFMRIAPELYLKKLVVGGLNRVYEIGKQFR 291
+EVETPMMN+IAGGA A+PF+THHNDL+M ++MRIAPEL+LK+LVVGGL+RVYEIG+QFR
Sbjct: 266 IEVETPMMNVIAGGATAKPFITHHNDLDMDMYMRIAPELFLKQLVVGGLDRVYEIGRQFR 325
Query: 292 NEGIDLTHNPEFTTCEFYMAYKDYYDLMEITENMLSGMVYELTKGSYKIKYHADGLD-KD 350
NEGID+THNPEFTTCEFY AY D YDLM++TE M S MV E+T GSY IKYH D D
Sbjct: 326 NEGIDMTHNPEFTTCEFYQAYADVYDLMDMTELMFSEMVKEIT-GSYIIKYHPDPADPAK 384
Query: 351 PIEIDFTPPFRRIDMIEGLEEMAGLSIPK--DLTSAEANQYLRDACLKYEIKCPPPETTA 408
+E++F+ P++RI+MIE LE++ + P L +AE ++L+ + +++CPPP T A
Sbjct: 385 ELELNFSRPWKRINMIEELEKVFNVKFPSGDQLHTAETGEFLKKILVDNKLECPPPLTNA 444
Query: 409 RLLDKLVGHFLEETCVNPTFIINHPEIMSPLAKWHRTKPGLTERFELFINKHELANAYTE 468
R+LDKLVG LE+TC+NPTFI HP++MSPLAK+ R +PGL ERFE+F+ E+ NAYTE
Sbjct: 445 RMLDKLVGE-LEDTCINPTFIFGHPQMMSPLAKYSRDQPGLCERFEVFVATKEICNAYTE 503
Query: 469 LNDPVVQRQRFADQLKDRQSGDDEAMALDETFCTALEYGLPPTAGWGLGIDRLTMLLTDS 528
LNDP QR RF +Q + + GDDEA +DETFC ALEYGLPPT GWG GIDRL M LTDS
Sbjct: 504 LNDPFDQRARFEEQARQKDQGDDEAQLVDETFCNALEYGLPPTGGWGCGIDRLAMFLTDS 563
Query: 529 QNIKEVLLFPAMKP 542
I+EVLLFP +KP
Sbjct: 564 NTIREVLLFPTLKP 577
>SYK_THEMA (Q9X231) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA
ligase) (LysRS)
Length = 502
Score = 402 bits (1034), Expect = e-112
Identities = 224/523 (42%), Positives = 321/523 (60%), Gaps = 39/523 (7%)
Query: 21 QYLENRLKYLSTEKEEGRNPYPHKFSATMTIKQYIKEYEGLSDGQHLDDVSVSLTGKIMH 80
++ E RLK + + G PYP+KF +T ++ ++Y+ L G+ L+ +S G++M
Sbjct: 4 EFKEQRLKEIQELRSMGIEPYPYKFEKELTAREIREKYDYLQAGEVLESEKLSFAGRVMS 63
Query: 81 KRSSGAKLVFYDLHDDGFKVQVMADASKSDLNEAGFDKVHSNVKRGDIVGITGFPGKSRK 140
R G K F+ + DD ++Q A + K H VK GD VG+ GFP KS+
Sbjct: 64 IRHHG-KTAFFHMKDDTGRIQAYIKADSVGKEKMDLFKRH--VKIGDFVGVRGFPFKSKT 120
Query: 141 GELSIFPKTFVVLSHCLHMMPRQKSAAAAAADNAWLPGKTRNPEAYTLKDQETRYRLRHL 200
GEL+I+ + + +LS L +P + W + +KD+E YR R+L
Sbjct: 121 GELTIYVQEYTLLSKALRPLPEK-----------W----------HGIKDKEIIYRQRYL 159
Query: 201 DLMLNTEVREIFRTRSKIISYVRSFLDKLDFLEVETPMMNMIAGGAAARPFVTHHNDLNM 260
+L++N E E F+ R K + +R FL+ F+EVETP+++ + GGA ARPFVTH N ++
Sbjct: 160 ELIVNDEAIERFKKRFKAVRVIREFLNSRGFIEVETPILHYVTGGAEARPFVTHLNVFDI 219
Query: 261 RLFMRIAPELYLKKLVVGGLNRVYEIGKQFRNEGIDLTHNPEFTTCEFYMAYKDYYDLME 320
+++RIAPELYLK+L+VGG ++YEIGK FRNEGI H+PEFT+ E Y AY DY D+M+
Sbjct: 220 DMYLRIAPELYLKRLIVGGFEKIYEIGKNFRNEGISYKHSPEFTSIEIYQAYADYNDMMD 279
Query: 321 ITENMLSGMVYELTKGSYKIKYHADGLDKDPIEIDFTPPFRRIDMIEGLEEMAGLSIPKD 380
+TE ++ +V + T G+ KI Y EIDFTPP++R+ M + L+E G+ I +D
Sbjct: 280 LTEELIVEVV-KRTCGTLKISYQGK-------EIDFTPPWKRVRMRDFLKEKLGVDILED 331
Query: 381 LTSAEANQYLRDACLKYEIKCPPPETTARLLDKLVGHFLEETCVNPTFIINHPEIMSPLA 440
+ L + ++ EIK A L+DKL +EE VNPTFII+HP ++SPLA
Sbjct: 332 PDEVLLKK-LEEHGVELEIK-----NRAHLIDKL-RDLVEEELVNPTFIIDHPVVISPLA 384
Query: 441 KWHRTKPGLTERFELFINKHELANAYTELNDPVVQRQRFADQLKDRQSGDDEAMALDETF 500
K HR P LTERFEL I E+ANA++ELNDPV Q QRF +Q K R+ GD+EA +D F
Sbjct: 385 KRHREDPRLTERFELIIFGREIANAFSELNDPVDQYQRFLEQAKMREEGDEEAHMMDLDF 444
Query: 501 CTALEYGLPPTAGWGLGIDRLTMLLTDSQNIKEVLLFPAMKPQ 543
ALEYG+PPT G G+G+DRL M +TDS I++V+ FP +KP+
Sbjct: 445 VRALEYGMPPTGGLGIGLDRLFMFITDSPTIRDVIPFPIVKPK 487
>SYK_CLOTE (Q899G7) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA
ligase) (LysRS)
Length = 502
Score = 400 bits (1027), Expect = e-111
Identities = 224/531 (42%), Positives = 330/531 (61%), Gaps = 45/531 (8%)
Query: 15 EDMDPTQYLENRLKYLSTEKEEGRNPYPHKFSATMTIKQYIKEYEGLSDGQHLDDVSVSL 74
E+ + Q ++ R + + EG++P F T + + E E S+ + L+D V++
Sbjct: 11 EEQEFNQLIQERRQKFFDLQAEGKDP----FEVTKVERTHTSE-EIKSNFEELEDKEVTV 65
Query: 75 TGKIMHKRSSGAKLVFYDLHDDGFKVQVMADASKSDLNEAGFDKV--HSNVKRGDIVGIT 132
G++M KR G K F D+HD K+Q+ +N+ G +++ + + GD V IT
Sbjct: 66 AGRLMSKRVHG-KAGFSDIHDRYGKIQLYIK-----INDVGEERLKEYKSFDIGDFVTIT 119
Query: 133 GFPGKSRKGELSIFPKTFVVLSHCLHMMPRQKSAAAAAADNAWLPGKTRNPEAYTLKDQE 192
G K+R GE+SI F +++ L +P + W + LKD +
Sbjct: 120 GTVFKTRTGEVSIHITDFKLIAKSLKPLPEK-----------W----------HGLKDPD 158
Query: 193 TRYRLRHLDLMLNTEVREIFRTRSKIISYVRSFLDKLDFLEVETPMMNMIAGGAAARPFV 252
RYR R++DL++N +VR+ F R+KII Y+R FLD D++EVETP+++ IAGGAAARPF
Sbjct: 159 LRYRQRYVDLIVNEDVRDTFMKRTKIIKYMREFLDAKDYIEVETPVLSPIAGGAAARPFT 218
Query: 253 THHNDLNMRLFMRIAPELYLKKLVVGGLNRVYEIGKQFRNEGIDLTHNPEFTTCEFYMAY 312
THHN L++ +++RIA ELYLK+L+VGG +VYEIGK FRNEGID+ HNPEFT E Y AY
Sbjct: 219 THHNALDIDMYLRIATELYLKRLIVGGFEKVYEIGKNFRNEGIDIRHNPEFTMIELYEAY 278
Query: 313 KDYYDLMEITENMLSGMVYELTKGSYKIKYHADGLDKDPIEIDFTPPFRRIDMIEGLEEM 372
DY D+MEITENM++ + E G+ K+KY + EI+F PP++RI M++ ++E
Sbjct: 279 ADYNDMMEITENMVA-YIAEKVCGNTKVKY-------EETEIEFRPPWKRITMVDSVKEY 330
Query: 373 AGLSIPKDLTSAEANQYLRDACLKYEIKCPPPE-TTARLLDKLVGHFLEETCVNPTFIIN 431
+G+ + T EA + ++ +E+K + T A +L+ ++E+ + PTF+ +
Sbjct: 331 SGVDFNEIKTDEEARELVKGK--DFELKKKLEDCTKADILNLFFEEYVEKNLIQPTFVCD 388
Query: 432 HPEIMSPLAKWHRTKPGLTERFELFINKHELANAYTELNDPVVQRQRFADQLKDRQSGDD 491
+P +SPL+K P TERFE F+ EL NAYTELNDP+VQ++RF QLK+R+ GDD
Sbjct: 389 YPVEISPLSKKKNDNPEYTERFEGFVYGRELCNAYTELNDPIVQKERFIQQLKERELGDD 448
Query: 492 EAMALDETFCTALEYGLPPTAGWGLGIDRLTMLLTDSQNIKEVLLFPAMKP 542
EA +DE F ALE G+PPT G G+G+DRL M LTDS +I++V+LFP MKP
Sbjct: 449 EAFMMDEDFINALEIGMPPTGGLGIGVDRLVMFLTDSHSIRDVILFPTMKP 499
>SYK_CHLTE (Q8KCM7) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA
ligase) (LysRS)
Length = 511
Score = 391 bits (1004), Expect = e-108
Identities = 222/537 (41%), Positives = 324/537 (59%), Gaps = 43/537 (8%)
Query: 14 EEDMDPTQYLENRLKYLSTEK----EEGRNPYPHKFSATMTIKQYIKEYEGLSDGQHLDD 69
+ D P L +++K E+ E G NPYP+KF T T K I + SD D
Sbjct: 11 QNDPSPAVSLNDQMKRRFEERTHLAEAGINPYPYKFDVTTTSKAIIDSF---SDENPAD- 66
Query: 70 VSVSLTGKIMHKRSSGAKLVFYDLHDDGFKVQVMADASKSDLNEAGFDKVHSNVKRGDIV 129
VS+ G+IM R G K F + D ++Q+ K D+ EA ++ + GDIV
Sbjct: 67 --VSVAGRIMAIRRMG-KASFLHIQDSEGRIQIYL--KKDDVGEASYN-TFKLLDIGDIV 120
Query: 130 GITGFPGKSRKGELSIFPKTFVVLSHCLHMMPRQKSAAAAAADNAWLPGKTRNPEAYTLK 189
G++GF K++ GE+S+ + F +L+ L +P K + G+ +A++
Sbjct: 121 GVSGFTFKTKTGEISVHARQFELLAKSLRPIPIAKEKE--------VDGQKVIYDAFS-- 170
Query: 190 DQETRYRLRHLDLMLNTEVREIFRTRSKIISYVRSFLDKLDFLEVETPMMNMIAGGAAAR 249
D+E RYR R++DL++N EVR F R+KI++ +R++ +LEVETP++ I GGAAAR
Sbjct: 171 DRELRYRQRYVDLIVNPEVRGTFIKRTKIVALMRNYFASNGWLEVETPILQPIYGGAAAR 230
Query: 250 PFVTHHNDLNMRLFMRIAPELYLKKLVVGGLNRVYEIGKQFRNEGIDLTHNPEFTTCEFY 309
PF THHN L+M+L++RIA ELYLK+L+VGG + V+E K FRNEGID HNPEFT E Y
Sbjct: 231 PFTTHHNALDMQLYLRIANELYLKRLIVGGFDGVFEFAKDFRNEGIDRFHNPEFTQVELY 290
Query: 310 MAYKDYYDLMEITENMLSGMVYELTKGSYKIKYHADGLDKDPI---EIDFTPPFRRIDMI 366
+AYKDY +ME+ E++L +K +G D EI+ PPFRR+ +
Sbjct: 291 VAYKDYIWMMELVEDLL-----------HKACVEVNGKDSTMFLGNEINLKPPFRRLTIA 339
Query: 367 EGLEEMAGLSIPKDLTSAEANQYLRDACLKYEIKCPPPETTARLLDKLVGHFLEETCVNP 426
+ + E G+ I ++ LRD ++ P ++ +++D++ G F+E + P
Sbjct: 340 DSIREYTGMEI-----RGKSEAQLRDIAKDLGLELDPKISSGKIIDEIFGEFVEPKLIQP 394
Query: 427 TFIINHPEIMSPLAKWHRTKPGLTERFELFINKHELANAYTELNDPVVQRQRFADQLKDR 486
TFI ++PE MSPLAK HR++PGL ERFEL + E+ N+++ELNDPV+QR+R +Q + R
Sbjct: 395 TFITDYPEEMSPLAKKHRSEPGLVERFELIVGGKEVCNSFSELNDPVIQRERLEEQARLR 454
Query: 487 QSGDDEAMALDETFCTALEYGLPPTAGWGLGIDRLTMLLTDSQNIKEVLLFPAMKPQ 543
Q GDDEAM +DE F ALEYG+PP AG G+GIDR+ MLLT +I++V+ FP MKP+
Sbjct: 455 QRGDDEAMIVDEDFLRALEYGMPPCAGLGIGIDRMVMLLTGQDSIRDVIFFPHMKPE 511
>SYK_LEPIN (Q8F4P5) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA
ligase) (LysRS)
Length = 495
Score = 388 bits (997), Expect = e-107
Identities = 212/527 (40%), Positives = 327/527 (61%), Gaps = 35/527 (6%)
Query: 18 DPTQYLENRLKYLSTEKEEGRNPYPHKFSATMTIKQYIKEYEGLSDGQHLDDVSVSLTGK 77
+ + +E R++ + K++G NPYP +F K +++E G + L G+
Sbjct: 3 ESNELIEQRIQKIEELKKQGINPYPVRFFPDSKSKDIAEKFEKNPTGP---ETKFKLGGR 59
Query: 78 IMHKRSSGAKLVFYDLHDDGFKVQVMADASKSDLNEAGFDKVHSNVKRGDIVGITGFPGK 137
+ KR G K F L D+ +Q+ A +K DL E + + ++ GDI+G+ G+ K
Sbjct: 60 LHSKRVMG-KASFAHLKDNSGIIQLYA--TKDDLGETQYS-IFKSLDLGDIIGLEGYLFK 115
Query: 138 SRKGELSIFPKTFVVLSHCLHMMPRQKSAAAAAADNAWLPGKTRNPEAYTLKDQETRYRL 197
++KGE+++ + +L+ C+ +P K D D E RYR+
Sbjct: 116 TQKGEITLHVTSVELLAKCIRPLPVVKEKDGVVYD--------------AFADVEQRYRM 161
Query: 198 RHLDLMLNTEVREIFRTRSKIISYVRSFLDKLDFLEVETPMMNMIAGGAAARPFVTHHND 257
R++DL++N VR+ F TRSKI+S +RSFL + FLEVETPMM IAGGAAARPFVTHHN
Sbjct: 162 RYVDLIVNDHVRDTFITRSKIVSEIRSFLTQEGFLEVETPMMQPIAGGAAARPFVTHHNT 221
Query: 258 LNMRLFMRIAPELYLKKLVVGGLNRVYEIGKQFRNEGIDLTHNPEFTTCEFYMAYKDYYD 317
L+M+LF+RIAPELYLK+L+VGG++RV+E+ + FRNEGI HNPEFT E YMA+ D
Sbjct: 222 LDMQLFLRIAPELYLKRLIVGGMDRVFELNRNFRNEGISTKHNPEFTMMEAYMAFGDMST 281
Query: 318 LMEITENMLSGMVYELTKGSYKIKYHADGLDKDPIEIDFTPPFRRIDMIEGLEEMAGLSI 377
++++TE +++ + ++ G+ KI+Y D ID +PP++R ++ ++E +G+
Sbjct: 282 MLDLTERLITHLAQKIC-GTLKIQYGKD-------LIDLSPPWKRTTYVDIIKEYSGIDF 333
Query: 378 PKDLTSAEANQYLRDACLKYEI-KCPPPETTARLLDKLVGHFLEETCVNPTFIINHPEIM 436
+ ++ EA + + LK ++ KC +T ++ D++ E + P FI ++P+ +
Sbjct: 334 SQIISLEEAKKKASE--LKVDVSKC---QTIWKVADEVFSEKAEPNLIQPIFITDYPKEL 388
Query: 437 SPLAKWHRTKPGLTERFELFINKHELANAYTELNDPVVQRQRFADQLKDRQSGDDEAMAL 496
SPLAK + KPG ERFE ++ E+ NA+TELNDP Q++RF DQ+K R++GDDEA +
Sbjct: 389 SPLAKSNPDKPGYVERFEPYVAGREIGNAFTELNDPFDQKERFEDQVKQREAGDDEAFMM 448
Query: 497 DETFCTALEYGLPPTAGWGLGIDRLTMLLTDSQNIKEVLLFPAMKPQ 543
DE + ALEYG+PPT G G+GIDRL MLLT+S +I++ +LFP M+P+
Sbjct: 449 DEDYIRALEYGMPPTGGLGIGIDRLVMLLTNSHSIRDTILFPLMRPE 495
>SYK_THETN (Q8R7N1) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA
ligase) (LysRS)
Length = 499
Score = 386 bits (992), Expect = e-107
Identities = 222/529 (41%), Positives = 321/529 (59%), Gaps = 51/529 (9%)
Query: 21 QYLENRLKYLSTEKEEGRNPYP-HKFSATMTIKQYIKEYEGLSDGQHLDDVSVSLTGKIM 79
+ L R + L+ + G PY +F T +YE + + +V+L G+IM
Sbjct: 17 ELLRVRREKLNILRSMGIEPYGIDRFERTNLSSDIKNDYE------NFEGKTVTLAGRIM 70
Query: 80 HKRSSGAKLVFYDLHDDGFKVQVMADASKSDLNEAGFD-KVHSNVKRGDIVGITGFPGKS 138
KRS G K F D+ D ++Q+ N G + ++ + GDI+G+TG K+
Sbjct: 71 TKRSHG-KASFADIQDRDGRIQIYVRYD----NVGGKNYEIFKLLDIGDIIGVTGEVFKT 125
Query: 139 RKGELSIFPKTFVVLSHCLHMMPRQKSAAAAAADNAWLPGKTRNPEAYTLKDQETRYRLR 198
+ GE++I K F +L L ++P + W + LKD + RYR R
Sbjct: 126 KTGEITINVKDFKLLCKSLQVLPEK-----------W----------HGLKDPDLRYRQR 164
Query: 199 HLDLMLNTEVREIFRTRSKIISYVRSFLDKLDFLEVETPMMNMIAGGAAARPFVTHHNDL 258
++DL++N VRE+F R+KII +R FLD FLEVETP+++ IAGGAAARPF+THHN L
Sbjct: 165 YVDLIINPSVREVFLKRTKIIKAIREFLDNRGFLEVETPVLHTIAGGAAARPFITHHNAL 224
Query: 259 NMRLFMRIAPELYLKKLVVGGLNRVYEIGKQFRNEGIDLTHNPEFTTCEFYMAYKDYYDL 318
++ +++RIA EL+LK+L+VGG +VYEIG+ FRNEG+D+ HNPEFT E Y AY DY+ +
Sbjct: 225 DIDMYLRIALELHLKRLIVGGFEKVYEIGRVFRNEGMDIRHNPEFTLLELYEAYTDYHGM 284
Query: 319 MEITENMLSGMVYELTKGSYKIKYHADGLDKDPIEIDFTPPFRRIDMIEGLEEMAGLSIP 378
ME+TE + + V E GS KI Y EID TPP++RI M++ ++E G+
Sbjct: 285 MELTEQLFA-YVAEKVNGSTKIIYQG-------TEIDLTPPWKRITMVDAIKEYVGIDFE 336
Query: 379 KDLTSAEANQYLRDACLKYEIKCP---PPETTARLLDKLVGHFLEETCVNPTFIINHPEI 435
K T EA + +D L E+K P E A + D+LV E+ + PTF++++P
Sbjct: 337 KVATDEEARKIAKD--LNLELKKPDMKKGEVIALVFDELV----EKHLIQPTFVMDYPVE 390
Query: 436 MSPLAKWHRTKPGLTERFELFINKHELANAYTELNDPVVQRQRFADQLKDRQSGDDEAMA 495
+SPLAK R P T RFE FI E+ANA++ELNDP+ Q++RF +QL+ R++GD+EA
Sbjct: 391 VSPLAKRKRDNPAFTSRFEAFIYGREVANAFSELNDPIDQKERFLEQLRQREAGDEEAHM 450
Query: 496 LDETFCTALEYGLPPTAGWGLGIDRLTMLLTDSQNIKEVLLFPAMKPQD 544
+DE F ALE G+PPT G G+G+DRL M +TDS +I++V+LFP MKP+D
Sbjct: 451 MDEDFINALEVGMPPTGGLGIGVDRLVMFMTDSYSIRDVILFPTMKPKD 499
>SYK_AQUAE (O67258) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA
ligase) (LysRS)
Length = 597
Score = 385 bits (989), Expect = e-106
Identities = 215/472 (45%), Positives = 296/472 (62%), Gaps = 35/472 (7%)
Query: 72 VSLTGKIMHKRSSGAKLVFYDLHDDGFKVQVMADASKSDLNEAGFDKVHSNVKRGDIVGI 131
VSL G+++ RS G K +F + D K+Q+ K + E + + GDIVG+
Sbjct: 154 VSLAGRLVSMRSMG-KAIFGHIQDLTGKIQIYL--KKDVIGEEKLKFFNDYIDVGDIVGV 210
Query: 132 TGFPGKSRKGELSIFPKTFVVLSHCLHMMPRQKSAAAAAADNAWLPGKTRNPEAYTLKDQ 191
G ++ GEL++ + + +L+ LH +P + W + LKD
Sbjct: 211 RGKLFRTNTGELTVEVEEYQLLAKSLHPLPEK-----------W----------HGLKDV 249
Query: 192 ETRYRLRHLDLMLNTEVREIFRTRSKIISYVRSFLDKLDFLEVETPMMNMIAGGAAARPF 251
E RYR R+LDL+ N E R IF R+K+I+ +R F + F+EVETP++ IA GA ARPF
Sbjct: 250 EVRYRQRYLDLIANPEARRIFMLRTKLITEMRKFFEMHGFIEVETPILQPIASGANARPF 309
Query: 252 VTHHNDLNMRLFMRIAPELYLKKLVVGGLNRVYEIGKQFRNEGIDLTHNPEFTTCEFYMA 311
VT+HN L L++RIAPELYLK+L+VGG RVYEIGK FRNE +D THNPEFT EFY A
Sbjct: 310 VTYHNFLETELYLRIAPELYLKRLIVGGFPRVYEIGKNFRNESVDRTHNPEFTMVEFYAA 369
Query: 312 YKDYYDLMEITENMLSGMVYELTKGSYKIKYHADGLDKDPIEIDFTPPFRRIDMIEGLEE 371
Y DY+DL++ TE+M ++ E T G+ K+KY E+DF+PPF+++ + L+E
Sbjct: 370 YWDYHDLIKFTEDMFVYLL-EKTLGTLKVKY-------GEWELDFSPPFKKVRYFDLLKE 421
Query: 372 MAGLSIPKDLTSAEANQYLRDACLKYEIKCPPPETTARLLDKLVGHFLEETCVNPTFIIN 431
G L E LR + EI T A+LLDK+ EE + PTF+I+
Sbjct: 422 KTGKDKDFFLKDLEG---LRKLAKELEIPDVERMTHAKLLDKVFEKVAEEDLIQPTFVID 478
Query: 432 HPEIMSPLAKWHRTKPGLTERFELFINKHELANAYTELNDPVVQRQRFADQLKDRQSGDD 491
P+I+SPLAK HR P L ERFEL I ++E+ANAYTELNDP Q++RF +QLK++Q GD+
Sbjct: 479 FPKILSPLAKTHREDPDLVERFELIIARYEVANAYTELNDPFDQKERFLEQLKEKQMGDE 538
Query: 492 EAMALDETFCTALEYGLPPTAGWGLGIDRLTMLLTDSQNIKEVLLFPAMKPQ 543
EAM +DE F ALEYG+PPTAG G+GIDRL M+L ++ +I+EV+LFP +KP+
Sbjct: 539 EAMDMDEDFIRALEYGMPPTAGEGIGIDRLVMILANTDSIREVILFPQLKPE 590
Score = 35.0 bits (79), Expect = 0.52
Identities = 17/36 (47%), Positives = 22/36 (60%)
Query: 24 ENRLKYLSTEKEEGRNPYPHKFSATMTIKQYIKEYE 59
E RLK L +E+G NPYP++F T I K+YE
Sbjct: 23 EVRLKKLQELREKGINPYPYRFEVTDFIGNIRKQYE 58
>SYK_CLOAB (Q97EB7) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA
ligase) (LysRS)
Length = 515
Score = 380 bits (977), Expect = e-105
Identities = 221/535 (41%), Positives = 320/535 (59%), Gaps = 51/535 (9%)
Query: 14 EEDMDPTQYLENRLKYLSTEKEEGRNPYP-HKFSATMTIKQYIKEYEGLSDGQHLDDVSV 72
+E+ L+ R + LS +E G++P+ +K T T KQ + Y+ L+D V
Sbjct: 21 KEEAKMNDLLKERRQKLSDAQERGKDPFDVYKVERTHTSKQIVDNYD------ELEDKIV 74
Query: 73 SLTGKIMHKRSSGAKLVFYDLHDDGFKVQVMADASKSDLNEAGFDKVHS--NVKRGDIVG 130
++ G++M KR G K F D++D K+Q+ +++ G +K+ GD V
Sbjct: 75 TVAGRLMSKRVHG-KAGFSDIYDRYGKIQLYLK-----IDDVGEEKLKEFKTFDIGDFVV 128
Query: 131 ITGFPGKSRKGELSIFPKTFVVLSHCLHMMPRQKSAAAAAADNAWLPGKTRNPEAYTLKD 190
ITG K++ GE+++ +++ L +P + + LKD
Sbjct: 129 ITGKVFKTKTGEITLHVTKLELIAKSLKPLPEK---------------------FHGLKD 167
Query: 191 QETRYRLRHLDLMLNTEVREIFRTRSKIISYVRSFLDKLDFLEVETPMMNMIAGGAAARP 250
+ +YR R++DL++N +VRE F R+ II VR FLD D+LEVETP+++ IA GA+ARP
Sbjct: 168 PDLKYRQRYVDLIINQDVRETFMKRTAIIKAVREFLDNKDYLEVETPVLSTIASGASARP 227
Query: 251 FVTHHNDLNMRLFMRIAPELYLKKLVVGGLNRVYEIGKQFRNEGIDLTHNPEFTTCEFYM 310
F THHN L++ + +RIA ELYLK+L+VGG +VYEIGK FRNEGID+ HNPEFT E Y
Sbjct: 228 FSTHHNALDLDMHLRIATELYLKRLIVGGFEKVYEIGKDFRNEGIDVRHNPEFTMIELYE 287
Query: 311 AYKDYYDLMEITENMLSGMVYELTKGSYKIKYHADGLDKDPIEIDFTPPFRRIDMIEGLE 370
AY DY D+MEITENM++ + G+ KI Y + EID TPP+RR+ M++ ++
Sbjct: 288 AYADYNDMMEITENMVA-YACQKVNGTTKITY-------EGTEIDLTPPWRRVTMVDIVK 339
Query: 371 EMAGLSIPKDLTSAEANQYLRDAC--LKYEIK-CPPPETTARLLDKLVGHFLEETCVNPT 427
E +G+ T EA + ++ LK E+K C T +L+ L + E+ + PT
Sbjct: 340 EHSGIDFSTVKTDEEAREIAKEKKLELKKELKDC----TKGDILNALFEEYGEKKLIQPT 395
Query: 428 FIINHPEIMSPLAKWHRTKPGLTERFELFINKHELANAYTELNDPVVQRQRFADQLKDRQ 487
F+ ++P +SPL K R P TERFE FI E+ NAY+ELNDP+VQ+ RF QLK+R+
Sbjct: 396 FVCDYPVEISPLTKKKRGNPEYTERFEGFIYGREICNAYSELNDPIVQKDRFMQQLKERE 455
Query: 488 SGDDEAMALDETFCTALEYGLPPTAGWGLGIDRLTMLLTDSQNIKEVLLFPAMKP 542
GDDEA +D+ F ALE G+PPT G G+G+DRL M LTDS +I++V+LFP MKP
Sbjct: 456 LGDDEAYQMDDDFINALEIGMPPTGGMGMGMDRLVMFLTDSPSIRDVILFPTMKP 510
>SYK2_METMA (Q8PVP6) Lysyl-tRNA synthetase 2 (EC 6.1.1.6)
(Lysine--tRNA ligase 2) (LysRS 2)
Length = 511
Score = 380 bits (977), Expect = e-105
Identities = 229/525 (43%), Positives = 316/525 (59%), Gaps = 47/525 (8%)
Query: 24 ENRLKYLSTEKEEGRNPYPHKFSATMTIKQYIKEYEGLSDGQHLDDVSVSLTGKIMHKRS 83
+++L L+ +G NPYP+KF I + ++++E D + + ++V G++ + R
Sbjct: 30 DSKLAKLNGVISQGLNPYPYKFEKDEDICEILEKFE---DFEKNEGLTVRTAGRLYNIRK 86
Query: 84 SGAKLVFYDLHDDGFKVQVMADASKSDLNEAGFDKVHSNVKRGDIVGITGFPGKSRKGEL 143
G K++F DL D +VQV+ K +L + F+ + V GDI+G+ G ++++GE
Sbjct: 87 HG-KMIFADLGDQAGRVQVLV--RKGNLPDEEFEIFKNLVDSGDIIGVQGDLFRTKRGEN 143
Query: 144 SIFPKTFVVLSHCLHMMPRQKSAAAAAADNAWLPGKTRNPEAYTLKDQETRYRLRHLDLM 203
SI F +LS L +P + + LKD ETRYR R+LDL+
Sbjct: 144 SISVSEFSLLSKSLCALPEK---------------------FHGLKDVETRYRKRYLDLI 182
Query: 204 LNTEVREIFRTRSKIISYVRSFLDKLDFLEVETPMMNMIAGGAAARPFVTHHNDLNMRLF 263
+N E REIF RSK+IS +R FL +FLE ETP++ + GGA ARPF T HN L LF
Sbjct: 183 VNAEKREIFVMRSKLISEIRRFLTDREFLEFETPILQTVYGGANARPFTTFHNCLGQNLF 242
Query: 264 MRIAPELYLKKLVVGGLNRVYEIGKQFRNEGIDLTHNPEFTTCEFYMAYKDYYDLMEITE 323
+RIAPELYLK+LVVGG +V+EI K FRNE ID THNPEFT E Y AY+DY D+M++TE
Sbjct: 243 LRIAPELYLKRLVVGGYEKVFEICKNFRNEDIDTTHNPEFTMIEVYEAYRDYNDMMDLTE 302
Query: 324 NMLSGMVYELTKGSYKIKYHADGLDKDPIEIDFTPPFRRIDMIEGLEEMAGLSI----PK 379
+++S +V++LT GSY+++ I+ P++RI M + L+E AGL I +
Sbjct: 303 SLVSELVFKLT-GSYEVQMGEK-------TINLRSPWKRISMEDALKEYAGLDIFAHSIE 354
Query: 380 DLTSAEANQYLRDACLKYEIKCPPPETTARLLDKLVGHFLEETCVNPTFIINHPEIMSPL 439
DL + D YE E A L + LV E+ ++PTFI + P SPL
Sbjct: 355 DLKKIAIENRIED----YEKAKSHGEFLALLFEGLV----EDKLIDPTFIYDFPVENSPL 406
Query: 440 AKWHRTKPGLTERFELFINKHELANAYTELNDPVVQRQRFADQLKDRQSGDDEAMALDET 499
AK HR K G ERFELF+N ELAN Y+ELNDP+ Q +RF +Q K R+ GD EA +D
Sbjct: 407 AKNHREKAGFVERFELFLNGWELANGYSELNDPLEQEKRFEEQDKKRKLGDLEAQTVDYD 466
Query: 500 FCTALEYGLPPTAGWGLGIDRLTMLLTDSQNIKEVLLFPAMKPQD 544
F AL YGLPPT G GLGIDRLTM+L+ ++IKEV+LFP MK +D
Sbjct: 467 FINALGYGLPPTGGMGLGIDRLTMILSGLESIKEVILFPQMKRED 511
>SYK_BACHD (Q9KGG4) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA
ligase) (LysRS)
Length = 501
Score = 377 bits (969), Expect = e-104
Identities = 215/531 (40%), Positives = 317/531 (59%), Gaps = 38/531 (7%)
Query: 15 EDMDPTQYLENRLKYLSTEKEEGRNPYPHKFSATMTIKQYIKEYEGLSDGQHLDDV-SVS 73
E++ L R + L + EG NP+ KF T T + ++Y+ S + ++ V
Sbjct: 3 EELGLNDLLAVRREKLQNLEAEGANPFGGKFERTDTAQSMKEKYDAKSKEELEEETHEVV 62
Query: 74 LTGKIMHKRSSGAKLVFYDLHDDGFKVQVMADASKSDLNEAGFDKVHSNVKRGDIVGITG 133
L G++M KR G K F + D ++Q+ K + + +D + +++ GDIVG+ G
Sbjct: 63 LAGRVMTKRGKG-KAGFAHIQDLTGQIQIYV--RKDAVGDKSYD-LFTSIDIGDIVGVKG 118
Query: 134 FPGKSRKGELSIFPKTFVVLSHCLHMMPRQKSAAAAAADNAWLPGKTRNPEAYTLKDQET 193
K++ GELS+ + F +L+ L +P + + LKD E
Sbjct: 119 VAFKTKVGELSVKVQDFQLLTKSLRPLP---------------------DKYHGLKDVEQ 157
Query: 194 RYRLRHLDLMLNTEVREIFRTRSKIISYVRSFLDKLDFLEVETPMMNMIAGGAAARPFVT 253
RYR R+LDL++N EVR+ F RSKI+ +R +LD +LEVETP M+ I GGA+ARPFVT
Sbjct: 158 RYRQRYLDLIVNPEVRDTFVLRSKILQSMRRYLDDRGYLEVETPTMHSIPGGASARPFVT 217
Query: 254 HHNDLNMRLFMRIAPELYLKKLVVGGLNRVYEIGKQFRNEGIDLTHNPEFTTCEFYMAYK 313
HHN L+M L+MRIA EL+LK+L+VGG+ +VYEIG+ FRNEG+ HNPEFT E Y AY
Sbjct: 218 HHNALDMTLYMRIAIELHLKRLIVGGMEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYA 277
Query: 314 DYYDLMEITENMLSGMVYELTKGSYKIKYHADGLDKDPIEIDFTPPFRRIDMIEGLEEMA 373
DY D+ME+TE +++ + ++ G+ I Y E++ P +RR+ M+E ++E
Sbjct: 278 DYNDIMELTELLIAHIAKDVL-GTTTITYGEH-------EVNLEPKWRRVHMVEAIKEET 329
Query: 374 GLSIPKDLTSAEANQYLRDACLKYEIKCPPPETTARLLDKLVGHFLEETCVNPTFIINHP 433
G+ +++ EA R ++ + T ++++ HF+EE + PTF+ HP
Sbjct: 330 GVDFWNEMSDEEA----RALAKEHNVPVKETMTYGHVVNEFFEHFVEEKLIQPTFVYGHP 385
Query: 434 EIMSPLAKWHRTKPGLTERFELFINKHELANAYTELNDPVVQRQRFADQLKDRQSGDDEA 493
+SPLAK + P T+RFELFI E ANA++ELNDP+ QR RF QL +R+ GDDEA
Sbjct: 386 VAISPLAKKNPDDPRFTDRFELFIVGREHANAFSELNDPIDQRHRFEQQLVEREQGDDEA 445
Query: 494 MALDETFCTALEYGLPPTAGWGLGIDRLTMLLTDSQNIKEVLLFPAMKPQD 544
+DE F +LEYG+PPT G G+GIDRL MLLT+S +I++VLLFP M+ +D
Sbjct: 446 HMMDEDFVESLEYGMPPTGGLGIGIDRLVMLLTNSPSIRDVLLFPQMRHKD 496
>SYK2_METAC (Q8TSN5) Lysyl-tRNA synthetase 2 (EC 6.1.1.6)
(Lysine--tRNA ligase 2) (LysRS 2)
Length = 511
Score = 377 bits (968), Expect = e-104
Identities = 229/539 (42%), Positives = 314/539 (57%), Gaps = 39/539 (7%)
Query: 6 ENRPAAADEEDMDPTQYLENRLKYLSTEKEEGRNPYPHKFSATMTIKQYIKEYEGLSDGQ 65
EN P D + + +++L L+ +G +PYP++F I + + ++E D +
Sbjct: 12 ENMPLPDDVDLSGSRAFDDSKLAKLNGIISQGLDPYPYRFEKNGDICEILVKFE---DFE 68
Query: 66 HLDDVSVSLTGKIMHKRSSGAKLVFYDLHDDGFKVQVMADASKSDLNEAGFDKVHSNVKR 125
+ +SV G++ + R G K++F DL D ++QV+ K +L + F + +
Sbjct: 69 KNEGLSVRTAGRLYNIRKHG-KMIFADLGDQTGRIQVLI--RKGNLPDEEFATFKNLMDS 125
Query: 126 GDIVGITGFPGKSRKGELSIFPKTFVVLSHCLHMMPRQKSAAAAAADNAWLPGKTRNPEA 185
GDI+GI G ++++GE SI F +LS L +P +
Sbjct: 126 GDIIGIQGELFRTKRGENSISVSEFSLLSKSLCALPEK---------------------F 164
Query: 186 YTLKDQETRYRLRHLDLMLNTEVREIFRTRSKIISYVRSFLDKLDFLEVETPMMNMIAGG 245
+ LKD ETRYR R+LDL++N E REIF RSK+IS +R FL +FLE ETP++ + GG
Sbjct: 165 HGLKDVETRYRKRYLDLIVNAEKREIFVMRSKLISEIRRFLADREFLEFETPILQTVYGG 224
Query: 246 AAARPFVTHHNDLNMRLFMRIAPELYLKKLVVGGLNRVYEIGKQFRNEGIDLTHNPEFTT 305
A ARPF T HN L LF+RIAPELYLK+LVVGG +V+EI K FRNE ID THNPEFT
Sbjct: 225 ANARPFKTFHNCLGQNLFLRIAPELYLKRLVVGGYEKVFEISKNFRNEDIDTTHNPEFTM 284
Query: 306 CEFYMAYKDYYDLMEITENMLSGMVYELTKGSYKIKYHADGLDKDPIEIDFTPPFRRIDM 365
E Y AY+DY D+M++TE ++S +V+ LT G Y++K + I+ P++RI M
Sbjct: 285 IEVYEAYRDYNDMMDLTEALISELVFRLT-GGYEVKMGEN-------TINLRSPWKRISM 336
Query: 366 IEGLEEMAGLSIPKDLTSAEANQYLRDACLKYEIKCPPPETTARLLDKLVGHFLEETCVN 425
L+E AGL + +++ YE E A L + LV E+ VN
Sbjct: 337 EGALKEYAGLDVFSHSLEELKQIAIQNRIEDYEKAKSHGEFLALLFEGLV----EDKLVN 392
Query: 426 PTFIINHPEIMSPLAKWHRTKPGLTERFELFINKHELANAYTELNDPVVQRQRFADQLKD 485
PTFI + P SPLAK HR K G ERFELF+N ELAN Y+ELNDP+ Q +RF +Q K
Sbjct: 393 PTFIYDFPVENSPLAKNHREKEGFVERFELFLNGWELANGYSELNDPLEQEKRFEEQDKK 452
Query: 486 RQSGDDEAMALDETFCTALEYGLPPTAGWGLGIDRLTMLLTDSQNIKEVLLFPAMKPQD 544
R+ GD EA +D F AL YGLPPT G GLGIDRLTM+L ++IKEV+LFP MK +D
Sbjct: 453 RKLGDLEAQTVDYDFINALGYGLPPTGGMGLGIDRLTMILAGLESIKEVILFPQMKRED 511
>SYK_BACSU (P37477) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA
ligase) (LysRS)
Length = 499
Score = 375 bits (963), Expect = e-103
Identities = 212/530 (40%), Positives = 325/530 (61%), Gaps = 43/530 (8%)
Query: 14 EEDMDPTQYLENRLKYLSTEKEEGRNPYPHKFSATMTIKQYIKEYEGLSDGQHLDD--VS 71
EE D Q +++ L ++ G +P+ +F T ++ I Y+ L+ + L++ +
Sbjct: 9 EELNDQLQVRRDKMNQL---RDNGIDPFGARFERTHQSQEVISAYQDLTK-EELEEKAIE 64
Query: 72 VSLTGKIMHKRSSGAKLVFYDLHDDGFKVQVMADASKSDLNEAGFDKVHSNVKRGDIVGI 131
V++ G++M KR G K F L D ++Q+ K + + ++ + + GD++G+
Sbjct: 65 VTIAGRMMTKRGKG-KAGFAHLQDLEGQIQIYV--RKDSVGDDQYE-IFKSSDLGDLIGV 120
Query: 132 TGFPGKSRKGELSIFPKTFVVLSHCLHMMPRQKSAAAAAADNAWLPGKTRNPEAYTLKDQ 191
TG K+ GELS+ +F +L+ L +P + + LKD
Sbjct: 121 TGKVFKTNVGELSVKATSFELLTKALRPLP---------------------DKYHGLKDV 159
Query: 192 ETRYRLRHLDLMLNTEVREIFRTRSKIISYVRSFLDKLDFLEVETPMMNMIAGGAAARPF 251
E RYR R+LDL++N + + F TRSKII +R +LD +LEVETP M+ I GGA+ARPF
Sbjct: 160 EQRYRQRYLDLIVNPDSKHTFITRSKIIQAMRRYLDDHGYLEVETPTMHSIPGGASARPF 219
Query: 252 VTHHNDLNMRLFMRIAPELYLKKLVVGGLNRVYEIGKQFRNEGIDLTHNPEFTTCEFYMA 311
+THHN L++ L+MRIA EL+LK+L+VGGL +VYEIG+ FRNEG+ HNPEFT E Y A
Sbjct: 220 ITHHNALDIPLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEA 279
Query: 312 YKDYYDLMEITENMLSGMVYELTKGSYKIKYHADGLDKDPIEIDFTPPFRRIDMIEGLEE 371
Y DY D+M +TEN+++ + E+ G+ I+Y + +ID P ++RI M++ ++E
Sbjct: 280 YADYKDIMSLTENLVAHIAQEVL-GTTTIQYGEE-------QIDLKPEWKRIHMVDAVKE 331
Query: 372 MAGLSIPKDLTSAEANQYLRDACLKYEIKCPPPETTARLLDKLVGHFLEETCVNPTFIIN 431
G+ +++T +A +Y ++ +E++ T ++++ +EET + PTFI
Sbjct: 332 ATGVDFWEEVTVEQAREYAKE----HEVEIKDSMTVGHIINEFFEQKIEETLIQPTFIYG 387
Query: 432 HPEIMSPLAKWHRTKPGLTERFELFINKHELANAYTELNDPVVQRQRFADQLKDRQSGDD 491
HP +SPLAK + P T+RFELFI E ANA+TELNDP+ QR+RF QLK+R++G+D
Sbjct: 388 HPVEISPLAKKNPEDPRFTDRFELFIVGREHANAFTELNDPIDQRERFEAQLKEREAGND 447
Query: 492 EAMALDETFCTALEYGLPPTAGWGLGIDRLTMLLTDSQNIKEVLLFPAMK 541
EA +DE F ALEYG+PPT G G+GIDRL MLLT++ +I++VLLFP M+
Sbjct: 448 EAHLMDEDFVEALEYGMPPTGGLGIGIDRLVMLLTNAPSIRDVLLFPQMR 497
>SYK_PORGI (Q7MUV7) Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA
ligase) (LysRS)
Length = 578
Score = 375 bits (962), Expect = e-103
Identities = 215/516 (41%), Positives = 313/516 (59%), Gaps = 41/516 (7%)
Query: 37 GRNPYPHKFSATMTIKQYIKEYEGLSDG-QHLDDVSVSLTGKIMHKRSSGAKLVFYDLHD 95
G +PYP +A T+ Y E + +G +++ VS+ G+IM +R G K F +L D
Sbjct: 24 GIDPYP---AAEYTVNAYSAEIKRNFNGDENVAKRQVSIAGRIMSRRIMG-KATFMELQD 79
Query: 96 DGFKVQVMADASKSDLNEAGFDKVHSN--VKR----GDIVGITGFPGKSRKGELSIFPKT 149
++Q+ ++ D+ G DK N VK+ GD +G+ G+ +++ GE+S+ +
Sbjct: 80 AEGRIQIYI--TRDDICP-GEDKEFYNTVVKKCTDIGDFIGVKGYVFRTQMGEISVHVQE 136
Query: 150 FVVLSHCLHMMPRQKSAAAAAADNAWLPGKTRNPEAYTLKDQETRYRLRHLDLMLNTEVR 209
LS + +P K D D E RYR R++DL++N+ V+
Sbjct: 137 MTFLSKAIRPLPVVKEKDGEVFDG--------------FTDPEQRYRQRYVDLVVNSHVK 182
Query: 210 EIFRTRSKIISYVRSFLDKLDFLEVETPMMNMIAGGAAARPFVTHHNDLNMRLFMRIAPE 269
+IF R+ + + +RSF ++ ++EV+TP++ I GGAAARPF+THHN L++ L++RIA E
Sbjct: 183 DIFLKRTMVFNSMRSFFNECGYIEVDTPVLQSIPGGAAARPFITHHNALDIPLYLRIANE 242
Query: 270 LYLKKLVVGGLNRVYEIGKQFRNEGIDLTHNPEFTTCEFYMAYKDYYDLMEITENMLSGM 329
LYLK+L+VGG + VYE + FRNEG+D THNPEFT E Y+AYKDY +M TE ML +
Sbjct: 243 LYLKRLIVGGFDGVYEFSRNFRNEGMDRTHNPEFTAMEIYVAYKDYNWMMNFTEQMLERI 302
Query: 330 VYELTKGSYKIKYHADGLDKDPIEIDFTPPFRRIDMIEGLEEMAGLSIPKDLTSAEANQY 389
++ G+ ++K IDF P++R+ MIE + E G+ I + AE
Sbjct: 303 CMDVL-GTTQMKVGGK-------LIDFKAPYKRVTMIEAIHEHTGIDI-SGMNEAE---- 349
Query: 390 LRDACLKYEIKCPPPETTARLLDKLVGHFLEETCVNPTFIINHPEIMSPLAKWHRTKPGL 449
LR C K ++ +L+D++ G E+ + PTFI ++P+ MSPL K HRT P L
Sbjct: 350 LRQVCDKLGVEHNETMGKGKLIDEIFGEKCEKNYIQPTFITDYPKEMSPLTKEHRTNPEL 409
Query: 450 TERFELFINKHELANAYTELNDPVVQRQRFADQLKDRQSGDDEAMALDETFCTALEYGLP 509
TERFEL +N ELANAY+ELNDP+ QR+RF +QLK + GDDEAM +D F ALEYG+P
Sbjct: 410 TERFELMVNGKELANAYSELNDPIDQRERFEEQLKLSEKGDDEAMYIDNDFIRALEYGMP 469
Query: 510 PTAGWGLGIDRLTMLLTDSQNIKEVLLFPAMKPQDV 545
PT+G G+G+DRL MLLT ++I+EVLLFP MKP+ V
Sbjct: 470 PTSGMGIGMDRLVMLLTGQESIQEVLLFPQMKPEKV 505
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.319 0.136 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,044,025
Number of Sequences: 164201
Number of extensions: 2969162
Number of successful extensions: 8379
Number of sequences better than 10.0: 358
Number of HSP's better than 10.0 without gapping: 340
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 7293
Number of HSP's gapped (non-prelim): 541
length of query: 560
length of database: 59,974,054
effective HSP length: 115
effective length of query: 445
effective length of database: 41,090,939
effective search space: 18285467855
effective search space used: 18285467855
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Medicago: description of AC148970.12