BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC148819.6 - phase: 0
(156 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
KTN1_CHICK (Q90631) Kinectin 47 1e-05
MYHB_HUMAN (P35749) Myosin heavy chain, smooth muscle isoform (S... 46 4e-05
GAS8_HUMAN (O95995) Growth-arrest-specific protein 8 (Growth arr... 46 4e-05
HMMR_HUMAN (O75330) Hyaluronan mediated motility receptor (Intra... 45 7e-05
GAS8_MOUSE (Q60779) Growth-arrest-specific protein 8 (Growth arr... 45 9e-05
NUF1_YEAST (P32380) NUF1 protein (Spindle poly body spacer prote... 44 1e-04
KAR3_YEAST (P17119) Kinesin-like protein KAR3 (Nuclear fusion pr... 44 1e-04
EEA1_HUMAN (Q15075) Early endosome antigen 1 (Endosome-associate... 44 1e-04
USO1_YEAST (P25386) Intracellular protein transport protein USO1 44 1e-04
GCC1_HUMAN (Q96CN9) GRIP and coiled-coil domain-containing prote... 44 1e-04
KTN1_HUMAN (Q86UP2) Kinectin (Kinesin receptor) (CG-1 antigen) 44 2e-04
GOA4_HUMAN (Q13439) Golgi autoantigen, golgin subfamily A member... 43 2e-04
GCC1_MOUSE (Q9D4H2) GRIP and coiled-coil domain-containing prote... 43 2e-04
ANT1_ONCVO (P21249) Major antigen 43 2e-04
IF2_AQUAE (O67825) Translation initiation factor IF-2 43 3e-04
SBCC_CLOAB (Q97FK1) Nuclease sbcCD subunit C 42 4e-04
GOA3_MOUSE (P55937) Golgi autoantigen, golgin subfamily A member... 42 4e-04
NUM1_YEAST (Q00402) Nuclear migration protein NUM1 42 7e-04
TANA_XENLA (Q01550) Tanabin 41 0.001
MYSJ_DICDI (P54697) Myosin IJ heavy chain 41 0.001
>KTN1_CHICK (Q90631) Kinectin
Length = 1364
Score = 47.4 bits (111), Expect = 1e-05
Identities = 36/142 (25%), Positives = 69/142 (48%), Gaps = 5/142 (3%)
Query: 9 RRALKLLEEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQV 68
R + LE+E+ +++ +ES K ++ Q+ +I+ K IL + +
Sbjct: 371 RERINALEKEHGTFQSKIHVSYQESQQMKIKFQQRCEQMEAEISHLKQENTILRDAVSTS 430
Query: 69 HFEVESKYSSEIRDLK-DC--LMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMTSN 125
++ESK ++E+ L+ DC L+ E EKN ++ +L +K A++ QQQE
Sbjct: 431 TNQMESKQAAELNKLRQDCARLVNELGEKNSKLQQEELQKKNAEQAVAQLKVQQQEAERR 490
Query: 126 WQVETLKQKIMKLRKENEVLKR 147
W E ++ + K E+E ++
Sbjct: 491 W--EEIQVYLRKRTAEHEAAQQ 510
Score = 40.8 bits (94), Expect = 0.001
Identities = 34/144 (23%), Positives = 66/144 (45%), Gaps = 12/144 (8%)
Query: 9 RRALKLLEEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIA---AHKNHMQILANRL 65
+R+++ E ++ K+ + ++K+ AS E + +L +I K + L + L
Sbjct: 1160 QRSVEEEESKWKIKVEESQKELKQMRSSVASLEHEVERLKEEIKEVETLKKEREHLESEL 1219
Query: 66 DQVHFEVESKYSSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKM--------VD 117
++ E S Y SE+R+LKD L Q++ +D + +EL L K K+ VD
Sbjct: 1220 EKAEIE-RSTYVSEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKMKLSETLSKLKVD 1278
Query: 118 QQQEMTSNWQVETLKQKIMKLRKE 141
Q + + ++ + L +E
Sbjct: 1279 QNERQKVAGDLPKAQESLASLERE 1302
Score = 33.5 bits (75), Expect = 0.20
Identities = 32/137 (23%), Positives = 64/137 (46%), Gaps = 19/137 (13%)
Query: 6 QGHRRALKLLEEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRL 65
+G +K +E EK E ++ + + T++QL + ++ L
Sbjct: 873 KGKENQVKTMEALLEEK----EKEIVQKGERLKGQQDTVAQLTSKV------QELEQQNL 922
Query: 66 DQVHFEVESKYSSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMTSN 125
Q+ + +S+++DL+ L E+E+ + L ++ E+E+ A V Q Q M S
Sbjct: 923 QQLQ---QVPAASQVQDLESRLRGEEEQISKLKAVLEEKEREI----ASQVKQLQTMQS- 974
Query: 126 WQVETLKQKIMKLRKEN 142
+ E+ K +I +L++EN
Sbjct: 975 -ENESFKVQIQELKQEN 990
>MYHB_HUMAN (P35749) Myosin heavy chain, smooth muscle isoform (SMMHC)
Length = 1972
Score = 45.8 bits (107), Expect = 4e-05
Identities = 35/158 (22%), Positives = 78/158 (49%), Gaps = 9/158 (5%)
Query: 7 GHRRALKLLEEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLD 66
G R L ++E K +LEAQV+E + + E ++L+ + +N ++ + L+
Sbjct: 1238 GELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLN 1297
Query: 67 QVHFEV------ESKYSSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQ 120
+ + + SS+++D ++ L E +K +++ K++ LE+E + ++ D++
Sbjct: 1298 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL-DEEM 1356
Query: 121 EMTSNWQ--VETLKQKIMKLRKENEVLKRKFSHIEEGK 156
E N + + TL ++ +K+ + +EEGK
Sbjct: 1357 EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGK 1394
Score = 33.9 bits (76), Expect = 0.15
Identities = 35/152 (23%), Positives = 71/152 (46%), Gaps = 24/152 (15%)
Query: 16 EEEYNEKIARLEAQVK---ESLHEK-ASYEATISQLHGDIAAHKNHMQILANRLDQVHFE 71
EE+ +++ +L+ +++ HE+ A +A I++L +A + +Q RLD E
Sbjct: 1046 EEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDD---E 1102
Query: 72 VESKYSS---------EIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEM 122
+ K ++ I DL++ L +E+ +N ++ + L +EL K ++ D
Sbjct: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD-- 1160
Query: 123 TSNWQVETLKQKIMKLRKENEVLKRKFSHIEE 154
T Q+ ++ ++E EV K + EE
Sbjct: 1161 ------STATQQELRAKREQEVTVLKKALDEE 1186
Score = 33.9 bits (76), Expect = 0.15
Identities = 34/147 (23%), Positives = 65/147 (44%), Gaps = 20/147 (13%)
Query: 15 LEEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQVHFEVES 74
LEE +E ARLE + +A + Q+ D+ + +L E+
Sbjct: 920 LEEILHEMEARLEEEEDRGQQLQAERKKMAQQML-DLEEQLEEEEAARQKLQLEKVTAEA 978
Query: 75 KYSSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQE------------- 121
K I+ L+D ++ ++ N L+++ +LLE+ + + +++++
Sbjct: 979 K----IKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHES 1034
Query: 122 MTSNWQVETLKQKIMKLRKENEVLKRK 148
M S +V K++ K R+E E LKRK
Sbjct: 1035 MISELEVRLKKEE--KSRQELEKLKRK 1059
Score = 33.1 bits (74), Expect = 0.26
Identities = 35/123 (28%), Positives = 59/123 (47%), Gaps = 12/123 (9%)
Query: 22 KIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANR-LDQVHFEVESKYSSEI 80
KIA+LE QV++ EK + AT S D + +Q+ R + + + E K ++ +
Sbjct: 1822 KIAQLEEQVEQEAREKQA--ATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARV 1879
Query: 81 RDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMTSNWQVETLKQKIMKLRK 140
+ LK L +EE +N + L++EL + + + M +V LK KLR+
Sbjct: 1880 KQLKRQLEEAEEESQRINANRRKLQREL----DEATESNEAM--GREVNALKS---KLRR 1930
Query: 141 ENE 143
NE
Sbjct: 1931 GNE 1933
Score = 30.8 bits (68), Expect = 1.3
Identities = 35/142 (24%), Positives = 60/142 (41%), Gaps = 25/142 (17%)
Query: 28 AQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQVHFEVESKYSSEIRDLKDCL 87
A KE+ + S EA + QL D+AA + + +++ E+ S S
Sbjct: 1673 ATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR-------- 1724
Query: 88 MAEQEEKNDLNRKMQLLEKEL---------LLFKAKMVDQQQEMTSNWQVETLKQKIMK- 137
A Q+EK L ++ LE+EL + + + QQ E SN ++ T + K
Sbjct: 1725 NALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSN-ELATERSTAQKN 1783
Query: 138 ------LRKENEVLKRKFSHIE 153
L ++N+ L+ K +E
Sbjct: 1784 ESARQQLERQNKELRSKLHEME 1805
>GAS8_HUMAN (O95995) Growth-arrest-specific protein 8 (Growth
arrest-specific 11)
Length = 478
Score = 45.8 bits (107), Expect = 4e-05
Identities = 36/142 (25%), Positives = 79/142 (55%), Gaps = 8/142 (5%)
Query: 15 LEEEYNEKIARLEAQVKESLHEKASY--EATISQLHGDIAAHKNHMQILANRLDQVHFEV 72
+EE N +I L + +E+ + +Y + T++ L I + K M+ + + D + E+
Sbjct: 211 VEERKNGQIHTLMQRHEEAFTDIKNYYNDITLNNL-ALINSLKEQMEDMRKKEDHLEREM 269
Query: 73 ESKYSSEIRDLKDCLMAEQEEKNDLNRKMQLLEKE---LLLFKAKMVDQQQEMTS-NWQV 128
++ S + + L D L +EE +++ +++ E++ LL KA++ +++E+ W+
Sbjct: 270 -AEVSGQNKRLADPLQKAREEMSEMQKQLANYERDKQILLCTKARLKVREKELKDLQWEH 328
Query: 129 ETLKQKIMKLRKENEVLKRKFS 150
E L+Q+ K+++E + L RKF+
Sbjct: 329 EVLEQRFTKVQQERDELYRKFT 350
Score = 29.6 bits (65), Expect = 2.8
Identities = 29/152 (19%), Positives = 69/152 (45%), Gaps = 25/152 (16%)
Query: 22 KIARLEAQVKESLHEKASYEATISQLHGDIAA----------HKNHMQILANRLDQVHFE 71
K+A+ E +++ES+ K + ++A+ H + + N ++ E
Sbjct: 125 KLAQKEHRIQESVLRKDMRALKVELKEQELASEVVVKNLRLKHTEEITRMRNDFERQVRE 184
Query: 72 VESKYSSEIRDLKDCL---------MAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEM 122
+E+KY +++ L+D L E+ + ++ MQ E+ K + ++
Sbjct: 185 IEAKYDKKMKMLRDELDLRRKTELHEVEERKNGQIHTLMQRHEEAFTDIK----NYYNDI 240
Query: 123 TSN--WQVETLKQKIMKLRKENEVLKRKFSHI 152
T N + +LK+++ +RK+ + L+R+ + +
Sbjct: 241 TLNNLALINSLKEQMEDMRKKEDHLEREMAEV 272
>HMMR_HUMAN (O75330) Hyaluronan mediated motility receptor
(Intracellular hyaluronic acid binding protein)
(Receptor for hyaluronan-mediated motility) (CD168
antigen)
Length = 724
Score = 45.1 bits (105), Expect = 7e-05
Identities = 46/166 (27%), Positives = 82/166 (48%), Gaps = 19/166 (11%)
Query: 1 MTFSEQGHRRALKLLE---EEYNEKIARLEAQV----KESLHEKASYEATISQLHGDIAA 53
M ++G L++ + EE KIA+LE ++ KE + EK+ E + + +I+
Sbjct: 184 MMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIE-EISC 242
Query: 54 HKNHMQILANRLDQVHFEVESKYSSEIRDLKDCLMAE----QEEKNDLNRKMQLLEKELL 109
+ ++ + Q+ ++ K + EI LK L ++ DLN K QLLEKE
Sbjct: 243 ASDQVEKYKLDIAQLEENLKEK-NDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKE-- 299
Query: 110 LFKAKMVDQQQEMTSNW--QVETLKQKIMKLRKENEVLKRKFSHIE 153
K V++ +E N +++ LKQK + ++E E L++K I+
Sbjct: 300 --KEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQID 343
Score = 33.9 bits (76), Expect = 0.15
Identities = 23/90 (25%), Positives = 49/90 (53%), Gaps = 1/90 (1%)
Query: 62 ANRLDQVHFEVESKYSSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQE 121
A ++ + K +++ L+ + +E+ + ++Q LE EL +A++ +E
Sbjct: 66 ARKVKSSESKESQKNDKDLKILEKEIRVLLQERGAQDSRIQDLETELEKMEARLNAALRE 125
Query: 122 MTS-NWQVETLKQKIMKLRKENEVLKRKFS 150
TS + TL++++++L + NE+LK KFS
Sbjct: 126 KTSLSANNATLEKQLIELTRTNELLKSKFS 155
Score = 28.1 bits (61), Expect = 8.3
Identities = 27/125 (21%), Positives = 56/125 (44%), Gaps = 11/125 (8%)
Query: 14 LLEEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHM----QILANRLDQVH 69
+LE++ EK+ + E Q+ L ++ S LH + + + M + L Q
Sbjct: 326 ILEQQEREKLQQKELQIDSLLQQEKELS---SSLHQKLCSFQEEMVKEKNLFEEELKQTL 382
Query: 70 FEVESKYSSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMTSNWQVE 129
E++ E + + E+E K+ +++LLE++L K K + ++ ++ Q
Sbjct: 383 DELDKLQQKEEQAERLVKQLEEEAKSRA-EELKLLEEKL---KGKEAELEKSSAAHTQAT 438
Query: 130 TLKQK 134
L Q+
Sbjct: 439 LLLQE 443
>GAS8_MOUSE (Q60779) Growth-arrest-specific protein 8 (Growth
arrest-specific 11)
Length = 478
Score = 44.7 bits (104), Expect = 9e-05
Identities = 35/142 (24%), Positives = 80/142 (55%), Gaps = 8/142 (5%)
Query: 15 LEEEYNEKIARLEAQVKESLHEKASY--EATISQLHGDIAAHKNHMQILANRLDQVHFEV 72
+EE N +I+ L + +E+ + +Y + T++ L I + K M+ + + + + E+
Sbjct: 211 VEERKNGQISTLMQRHEEAFTDIKNYYNDITLNNL-ALINSLKEQMEDMRKKEEHMEREM 269
Query: 73 ESKYSSEIRDLKDCLMAEQEEKNDLNRKMQLLEKE---LLLFKAKMVDQQQEMTS-NWQV 128
++ + + R L D L ++E N++ +++ E++ L+ KA++ ++E+ W+
Sbjct: 270 -AEVTLQNRRLADPLQKAKDEMNEMQKRLGNHERDKQILVCTKARLKVAERELKDLKWEH 328
Query: 129 ETLKQKIMKLRKENEVLKRKFS 150
E L+Q+ +K+++E E L RKF+
Sbjct: 329 EVLEQRFIKVQQEREELYRKFA 350
>NUF1_YEAST (P32380) NUF1 protein (Spindle poly body spacer protein
SPC110)
Length = 944
Score = 44.3 bits (103), Expect = 1e-04
Identities = 40/141 (28%), Positives = 65/141 (45%), Gaps = 16/141 (11%)
Query: 16 EEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQVHFEVESK 75
+E Y +I L+ ++KE EK L + KN +Q L LD + V S+
Sbjct: 158 KELYINEIKSLKHEIKELRKEKNDTLNNYDTLEEETDDLKNRLQALEKELDAKNKIVNSR 217
Query: 76 YSSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMTSNWQVETLKQKI 135
++ D C+ EE+ + RK+ LE++L K DQ E+ +N V++L
Sbjct: 218 ---KVDDHSGCI----EEREQMERKLAELERKLKTVK----DQVLELENNSDVQSL---- 262
Query: 136 MKLRKENEVLKRKFSHIEEGK 156
KLR + + LK + + E K
Sbjct: 263 -KLRSKEDELKNLMNELNELK 282
Score = 35.0 bits (79), Expect = 0.068
Identities = 37/160 (23%), Positives = 73/160 (45%), Gaps = 30/160 (18%)
Query: 15 LEEE---YNEKIARLEA---QVKESL--------HEKASYEATISQLHGDIAAHKNHMQI 60
LE+E NEKI+ L A Q+K + H K +YE + L DI +K +
Sbjct: 510 LEDEKTTLNEKISNLAAENSQLKNKIEDNSTATHHMKENYEKQLESLRKDIEEYKESAKD 569
Query: 61 LANRLDQVHF-------EVESKYSSEIR-------DLKDCLMAEQEEKNDLNRKMQLLEK 106
++++++ +V K S +I+ DL L +++E + L + +K
Sbjct: 570 SEDKIEELKIRIAENSAKVSEKRSKDIKQKDEQISDLTQNLKLQEDEISSLKSIIDRYKK 629
Query: 107 ELLLFKAKMVDQQQEMTSNWQVETLKQKIMKLRKENEVLK 146
+ K++ + Q ++ N Q+ L+ K+++ E + L+
Sbjct: 630 DFNQLKSEQSNIQHDL--NLQILNLENKLIESEDELKSLR 667
Score = 33.5 bits (75), Expect = 0.20
Identities = 28/136 (20%), Positives = 62/136 (45%), Gaps = 12/136 (8%)
Query: 16 EEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQVHFEVESK 75
EEE + +L+ ++ + E S + I L + +N + ++ + +++
Sbjct: 408 EEELKKTNDKLQKDIRIAREETVSKDERIIDLQKKVKQLENDLFVIKKTHSESKTITDNE 467
Query: 76 YSSE---IRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMTSNWQVETLK 132
S+ I+ L++ L QE+ + + ++++ E + ++K+ D++ TL
Sbjct: 468 LESKDKLIKILENDLKVAQEKYSKMEKELKEREFNYKISESKLEDEKT---------TLN 518
Query: 133 QKIMKLRKENEVLKRK 148
+KI L EN LK K
Sbjct: 519 EKISNLAAENSQLKNK 534
Score = 30.8 bits (68), Expect = 1.3
Identities = 28/140 (20%), Positives = 63/140 (45%), Gaps = 4/140 (2%)
Query: 17 EEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQVHFEVESKY 76
++ +E+I+ L +K E +S ++ I + D K+ + + L+ +E+K
Sbjct: 597 KQKDEQISDLTQNLKLQEDEISSLKSIIDRYKKDFNQLKSEQSNIQHDLNLQILNLENKL 656
Query: 77 ---SSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMT-SNWQVETLK 132
E++ L+D E E + L LL K D+++E++ N +++ +
Sbjct: 657 IESEDELKSLRDSQKIEIENWKRKYNNLSLENDRLLTEKESASDKEREISILNRKLDEMD 716
Query: 133 QKIMKLRKENEVLKRKFSHI 152
++ L++ E KR+ +
Sbjct: 717 KEKWNLQESKEKYKRELQKV 736
Score = 30.4 bits (67), Expect = 1.7
Identities = 29/121 (23%), Positives = 58/121 (46%), Gaps = 3/121 (2%)
Query: 27 EAQVKESLHEKASYEATISQLHGDIA-AHKNHMQILANRLDQVHFEVESKYSSEIRDLKD 85
E Q+K+ ++A + + H A + ++ ++ N + + E++ + E D +
Sbjct: 126 EHQMKKERFDRALESKLLGKRHITYANSDISNKELYINEIKSLKHEIK-ELRKEKNDTLN 184
Query: 86 CLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMTSNWQVETLKQKIMKLRKENEVL 145
+EE +DL ++Q LEKEL K K+V+ ++ + +E +Q KL + L
Sbjct: 185 NYDTLEEETDDLKNRLQALEKELDA-KNKIVNSRKVDDHSGCIEEREQMERKLAELERKL 243
Query: 146 K 146
K
Sbjct: 244 K 244
>KAR3_YEAST (P17119) Kinesin-like protein KAR3 (Nuclear fusion
protein)
Length = 729
Score = 44.3 bits (103), Expect = 1e-04
Identities = 41/166 (24%), Positives = 83/166 (49%), Gaps = 29/166 (17%)
Query: 8 HRRALKLLEEEYNEKIARLE-AQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLD 66
+++ LK +E EY KI +L+ ++K+ +E+AS I ++ I + + +Q + N ++
Sbjct: 190 NKKELKQMENEYKTKIEKLKFMKIKQFENERASLLDKIEEVRNKITMNPSTLQEMLNDVE 249
Query: 67 QVHF--------EVESKYSSEI----RDLKDCLMAEQEEKNDLNRKMQLLEKELLL---- 110
Q H E +S++ +I + +++ ++E +N L K +L EK+ LL
Sbjct: 250 QKHMLEKEEWLTEYQSQWKKDIELNNKHMQEIESIKKEIENTL--KPELAEKKKLLTEKR 307
Query: 111 -----FKAKMVDQQQEMTSNWQVETLKQK-----IMKLRKENEVLK 146
K K+ ++++E T LKQK + K+++ E +K
Sbjct: 308 NAYEAIKVKVKEKEEETTRLRDEVALKQKTNLETLEKIKELEEYIK 353
>EEA1_HUMAN (Q15075) Early endosome antigen 1 (Endosome-associated
protein p162) (Zinc finger FYVE domain containing
protein 2)
Length = 1411
Score = 44.3 bits (103), Expect = 1e-04
Identities = 34/157 (21%), Positives = 80/157 (50%), Gaps = 19/157 (12%)
Query: 9 RRALKLLEEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQV 68
+ AL+ ++E N+ +L+ QV L +K + SQL + +K L + +++
Sbjct: 673 QNALQDKQQELNKITTQLD-QVTAKLQDKQEH---CSQLESHLKEYKEKYLSLEQKTEEL 728
Query: 69 HFEVESKY--SSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMTSNW 126
+++ S E++ K+ + + +++ LN ++L EL +K ++ ++E+ S+
Sbjct: 729 EGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATEL----SKQLEMEKEIVSST 784
Query: 127 QV---------ETLKQKIMKLRKENEVLKRKFSHIEE 154
++ E++KQK+ K +E ++LK+ F + +
Sbjct: 785 RLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQ 821
Score = 30.4 bits (67), Expect = 1.7
Identities = 32/151 (21%), Positives = 68/151 (44%), Gaps = 16/151 (10%)
Query: 18 EYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQVHFEVESKYS 77
E + +L+ + K+ + AS EATISQL ++A + + L ++ V ++ +
Sbjct: 243 ERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSV-NELT 301
Query: 78 SEIRDLKDCLMAEQEEKNDLNRK---MQLLEKEL-LLFKAKMVDQQQEMTSNWQVETLKQ 133
+ + L + L+ ++++ L K + +K + K +D QQ + ET
Sbjct: 302 QKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLH 361
Query: 134 KI-----------MKLRKENEVLKRKFSHIE 153
+I KL++E ++ K+ H++
Sbjct: 362 RIHVELSEKGEATQKLKEELSEVETKYQHLK 392
Score = 29.3 bits (64), Expect = 3.7
Identities = 32/181 (17%), Positives = 74/181 (40%), Gaps = 34/181 (18%)
Query: 6 QGHRRALKLLEEEYNEKIARLEAQVKESL-HEKASYEATISQLHGDIAAHKNHMQILANR 64
+G L L+E+ N + Q+ E L ++ S++ LH + K H++ +R
Sbjct: 557 EGETAVLNQLQEK-NHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDR 615
Query: 65 ---------------------LDQVHFEVESK----------YSSEIRDLKDCLMAEQEE 93
+ Q+ ++++K +++ DL++ L Q
Sbjct: 616 VLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNA 675
Query: 94 KNDLNRKMQLLEKELLLFKAKMVDQQQEMTS-NWQVETLKQKIMKLRKENEVLKRKFSHI 152
D +++ + +L AK+ D+Q+ + ++ K+K + L ++ E L+ + +
Sbjct: 676 LQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKL 735
Query: 153 E 153
E
Sbjct: 736 E 736
Score = 28.9 bits (63), Expect = 4.8
Identities = 31/142 (21%), Positives = 61/142 (42%), Gaps = 13/142 (9%)
Query: 12 LKLLEEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANR------- 64
LK + E ++I L+ + + +K + L + K + QIL ++
Sbjct: 1147 LKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEE 1206
Query: 65 LDQVHFEVESKYSSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMTS 124
L + E E+K SEI++ + + +E + L ++ L + L K + Q+
Sbjct: 1207 LKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQR---- 1262
Query: 125 NWQVETLKQKIMKLRKENEVLK 146
+V L+++ LR E VL+
Sbjct: 1263 --RVSELEKQTDDLRGEIAVLE 1282
Score = 28.1 bits (61), Expect = 8.3
Identities = 33/163 (20%), Positives = 74/163 (45%), Gaps = 20/163 (12%)
Query: 9 RRALKLLEEEYN---EKIARLEAQV---KESLHEKASYEATISQLHGDIAAHKNHMQILA 62
R+ LK +EE+ + E + Q+ + + E + +AT+ Q D A + +Q
Sbjct: 1046 RQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQ---DSAKKEQQLQERC 1102
Query: 63 NRLDQVHFEVESKYS------SEIRDLKDCLMAEQEEKNDLNR-----KMQLLEKELLLF 111
L + E K S++ ++++ +++E LN K++ +++ L
Sbjct: 1103 KALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLK 1162
Query: 112 KAKMVDQQQEMTSNWQVETLKQKIMKLRKENEVLKRKFSHIEE 154
AK + QQ++ + ++LK + + ++ ++LK + EE
Sbjct: 1163 DAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEE 1205
>USO1_YEAST (P25386) Intracellular protein transport protein USO1
Length = 1790
Score = 43.9 bits (102), Expect = 1e-04
Identities = 46/166 (27%), Positives = 84/166 (49%), Gaps = 24/166 (14%)
Query: 5 EQGHRRALKLLEEEYN---EKIARLEAQVK----ESLHEKASYEAT---ISQLHGDIAAH 54
E+ ++R L+ L+E+ E A++E +K ES EKA E + + +L I ++
Sbjct: 1458 ERDNKRDLESLKEQLRAAQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESN 1517
Query: 55 KNHMQILANRLDQVHFEVESKYSSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAK 114
+ ++ + + ++E S D+K+ Q EK+DL ++ EK++ K+K
Sbjct: 1518 ETELKSSMETIRKSDEKLEQSKKSAEEDIKNL----QHEKSDLISRINESEKDIEELKSK 1573
Query: 115 MVDQQQEMTSNWQVETLKQKIM----KLR---KENEVLKRKFSHIE 153
+ + E S ++ET+KQ++ K+R +EN VLK K IE
Sbjct: 1574 L---RIEAKSGSELETVKQELNNAQEKIRINAEENTVLKSKLEDIE 1616
Score = 42.4 bits (98), Expect = 4e-04
Identities = 38/161 (23%), Positives = 78/161 (47%), Gaps = 28/161 (17%)
Query: 16 EEEYNEKIARLEAQVK-------ESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQV 68
++EY +I+ L+ +++ E++++ + T +L ++AA+KN L N L+
Sbjct: 1049 KDEYESQISLLKEKLETATTANDENVNKISELTKTREELEAELAAYKN----LKNELE-T 1103
Query: 69 HFEVESKYSSEIRDLKDCLMAEQ-----------EEKNDLNRKMQLLEKEL--LLFKAKM 115
E K E+++ ++ L E+ ++ N L ++ LEKE L + K
Sbjct: 1104 KLETSEKALKEVKENEEHLKEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKK 1163
Query: 116 VDQQ---QEMTSNWQVETLKQKIMKLRKENEVLKRKFSHIE 153
++Q +E N ++ L +I ++ENE +K+K +E
Sbjct: 1164 YEEQIANKERQYNEEISQLNDEITSTQQENESIKKKNDELE 1204
Score = 39.3 bits (90), Expect = 0.004
Identities = 42/165 (25%), Positives = 79/165 (47%), Gaps = 29/165 (17%)
Query: 9 RRALKLLEEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQV 68
R L+ LE+E+ + A+L+ ++ +++ Y ISQL+ +I + + + + + D++
Sbjct: 1144 RANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDEITSTQQENESIKKKNDEL 1203
Query: 69 HFEVESKYS----------SEIRDLKDCLMAEQEEKNDLNRKMQLLE------------K 106
EV++ S SEI D + + E ++KN+ N + LLE K
Sbjct: 1204 EGEVKAMKSTSEEQSNLKKSEI-DALNLQIKELKKKNETN-EASLLESIKSVESETVKIK 1261
Query: 107 EL---LLFKAKMVDQQQEMTSNWQVETLKQKIMKLRKENEVLKRK 148
EL FK K V + ++ E K ++L+KE+E +K +
Sbjct: 1262 ELQDECNFKEKEVSELEDKLK--ASEDKNSKYLELQKESEKIKEE 1304
Score = 38.9 bits (89), Expect = 0.005
Identities = 35/128 (27%), Positives = 59/128 (45%), Gaps = 12/128 (9%)
Query: 32 ESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQVHFEVESKYSSEIRDLKDCLMAEQ 91
E L EK + TI L +I ++K+ + R D+ +E ++ LK+ L A Q
Sbjct: 1424 ELLEEKQN---TIKSLQDEILSYKDKI----TRNDEKLLSIERDNKRDLESLKEQLRAAQ 1476
Query: 92 EEKNDLNRKMQLLEKE-----LLLFKAKMVDQQQEMTSNWQVETLKQKIMKLRKENEVLK 146
E K + ++ LE+E L K+K + ++ E T LK + +RK +E L+
Sbjct: 1477 ESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLE 1536
Query: 147 RKFSHIEE 154
+ EE
Sbjct: 1537 QSKKSAEE 1544
Score = 38.1 bits (87), Expect = 0.008
Identities = 32/140 (22%), Positives = 64/140 (44%), Gaps = 13/140 (9%)
Query: 16 EEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQVHFEVESK 75
+E+ + E +K HEK+ + I++ DI K+ ++I A ++
Sbjct: 1532 DEKLEQSKKSAEEDIKNLQHEKSDLISRINESEKDIEELKSKLRIEAKSGSELE-----T 1586
Query: 76 YSSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMTSNW-QVETLKQK 134
E+ + ++ + EE L K++ +E+EL D+Q E+ SN + E L +
Sbjct: 1587 VKQELNNAQEKIRINAEENTVLKSKLEDIERELK-------DKQAEIKSNQEEKELLTSR 1639
Query: 135 IMKLRKENEVLKRKFSHIEE 154
+ +L +E + ++K EE
Sbjct: 1640 LKELEQELDSTQQKAQKSEE 1659
Score = 32.3 bits (72), Expect = 0.44
Identities = 30/138 (21%), Positives = 63/138 (44%), Gaps = 8/138 (5%)
Query: 12 LKLLEEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQVHFE 71
L +E+ +++RL+ K S E+ + E + +L +I + L++
Sbjct: 1322 LSKAKEKSESELSRLK---KTSSEERKNAEEQLEKLKNEIQIKNQAFEKERKLLNEGSST 1378
Query: 72 VESKYSSEIRDLKDCLMAEQEEK----NDLNRKMQLLEKELLLFKAKMVDQQQEMTSNWQ 127
+ +YS +I L+D L+ Q E +++ LEK + L ++++++Q + Q
Sbjct: 1379 ITQEYSEKINTLEDELIRLQNENELKAKEIDNTRSELEK-VSLSNDELLEEKQNTIKSLQ 1437
Query: 128 VETLKQKIMKLRKENEVL 145
E L K R + ++L
Sbjct: 1438 DEILSYKDKITRNDEKLL 1455
>GCC1_HUMAN (Q96CN9) GRIP and coiled-coil domain-containing protein
1 (Golgi coiled coil protein 1)
Length = 775
Score = 43.9 bits (102), Expect = 1e-04
Identities = 40/159 (25%), Positives = 76/159 (47%), Gaps = 23/159 (14%)
Query: 12 LKLLEEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQVH-- 69
LK L+E+ E ARL Q + E++ + + +L + + Q L RL++
Sbjct: 215 LKGLQEQIAETKARLITQQHDRAQEQSDHALMLRELQKLLQEERTQRQDLELRLEETREA 274
Query: 70 -------------FEVESKY-SSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKM 115
FE+++K + E+ +LK L A ++EKN + ++Q L++E K+
Sbjct: 275 LAGRAYAAEQMEGFELQTKQLTREVEELKSELQAIRDEKNQPDPRLQELQEEAARLKSHF 334
Query: 116 VDQ-QQEMTSNWQVETLKQKIMKLRKENEVLKRKFSHIE 153
Q QQEM E +LR++++V +++ + +E
Sbjct: 335 QAQLQQEMRKTALAED------QLRQQSQVEEQRVAALE 367
Score = 29.6 bits (65), Expect = 2.8
Identities = 23/120 (19%), Positives = 55/120 (45%), Gaps = 11/120 (9%)
Query: 29 QVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQVHFEVESKYSSEIRDLKDCLM 88
+V + LH+ + AT++ + K+ M+ + + K + DL+D
Sbjct: 153 EVDKRLHQLKTQLATLTSSLATVTQEKSRME--------ASYLADKKKMKQ--DLEDASN 202
Query: 89 AEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMTSNWQVETLK-QKIMKLRKENEVLKR 147
+EE+ L +++ L++++ KA+++ QQ + L +++ KL +E ++
Sbjct: 203 KAEEERARLEGELKGLQEQIAETKARLITQQHDRAQEQSDHALMLRELQKLLQEERTQRQ 262
>KTN1_HUMAN (Q86UP2) Kinectin (Kinesin receptor) (CG-1 antigen)
Length = 1357
Score = 43.5 bits (101), Expect = 2e-04
Identities = 40/163 (24%), Positives = 81/163 (49%), Gaps = 16/163 (9%)
Query: 5 EQGHRRALKLLEEEYNE--KIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILA 62
+Q +R ++L+E E K L+ QV++ L + + +A I Q H IAA + +LA
Sbjct: 544 QQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAA-QTSASVLA 602
Query: 63 NRLDQVHFEVESKYSSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQ--- 119
L +V E + +I+ +D L +E++ +++ ++ L KA++ Q
Sbjct: 603 EELHKVIAEKD----KQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALA 658
Query: 120 -QEMTSNWQVETLKQKIM----KLRKENEVLKRKFSH-IEEGK 156
++ + ++E ++Q + K+R E L+ + S+ +EE K
Sbjct: 659 NEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFK 701
Score = 37.4 bits (85), Expect = 0.014
Identities = 31/136 (22%), Positives = 62/136 (44%), Gaps = 5/136 (3%)
Query: 15 LEEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQVHFEVES 74
LE+E+N ++ +E+ + ++ Q+ +IA K IL + + ++ES
Sbjct: 383 LEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLES 442
Query: 75 KYSSEIRDLKD---CLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMTSNWQVETL 131
K S+E+ L+ L+ E EK ++ ++ +K ++ Q QE W E +
Sbjct: 443 KQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRW--EEV 500
Query: 132 KQKIMKLRKENEVLKR 147
+ I K E+E ++
Sbjct: 501 QSYIRKRTAEHEAAQQ 516
Score = 37.0 bits (84), Expect = 0.018
Identities = 33/143 (23%), Positives = 67/143 (46%), Gaps = 11/143 (7%)
Query: 12 LKLLEEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQVHFE 71
LK + E + KI +E ++ L + A+ E T+ L +I A K + + Q+
Sbjct: 799 LKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNV-----QLEKA 853
Query: 72 VESKYSSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMTSNWQVETL 131
+ +S++++L++ L ++E+ N + ++ EK+L + D Q+E E+L
Sbjct: 854 QQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEEN------ESL 907
Query: 132 KQKIMKLRKENEVLKRKFSHIEE 154
K + ++ + N S EE
Sbjct: 908 KAHVQEVAQHNLKEASSASQFEE 930
Score = 35.4 bits (80), Expect = 0.052
Identities = 34/156 (21%), Positives = 69/156 (43%), Gaps = 19/156 (12%)
Query: 9 RRALKLLEEEYNEKIARLEAQVKESLHEKASYEATISQLHG---DIAAHKNHMQILANRL 65
+R+++ E ++ K+ +K+ S E + +L DI + + L L
Sbjct: 1154 QRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHLEMEL 1213
Query: 66 DQVHFEVESKYSSEIRDLKDCLMAEQEEKND-------LNRKMQLLEKELLLFKAKMVDQ 118
++ E S Y +E+R+LKD L Q++ +D N ++ LL+ +L K+ +
Sbjct: 1214 EKAEME-RSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTE 1272
Query: 119 QQEM--------TSNWQVETLKQKIMKLRKENEVLK 146
Q E + +E ++ KI+K + V++
Sbjct: 1273 QNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIE 1308
Score = 31.6 bits (70), Expect = 0.75
Identities = 35/157 (22%), Positives = 72/157 (45%), Gaps = 20/157 (12%)
Query: 12 LKLLEEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANR------- 64
L+++ +E ++ RLEA +KE + +S + + + K+ ++ L +
Sbjct: 931 LEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASS 990
Query: 65 ------LDQVHFEVESKYS---SEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKM 115
L +V E E + S +E+ LKD + ++++ NDL R+ E L KM
Sbjct: 991 FPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDL-REKNWEAMEALASTEKM 1049
Query: 116 VDQQQEMTSNWQVETLKQKIMKLRKENEVLKRKFSHI 152
+ + TS + + ++ ++ + EVLK+ F +
Sbjct: 1050 LQDKVNKTSKERQQQVEAVELEAK---EVLKKLFPKV 1083
>GOA4_HUMAN (Q13439) Golgi autoantigen, golgin subfamily A member 4
(Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (72.1
protein)
Length = 2230
Score = 43.1 bits (100), Expect = 2e-04
Identities = 35/150 (23%), Positives = 71/150 (47%), Gaps = 2/150 (1%)
Query: 8 HRRALKLLEEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQ 67
H +++ E+ ++I +LE +KE ++A + L DI + +Q + +LD
Sbjct: 743 HEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLD- 801
Query: 68 VHFEVESKYSSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMTSN-W 126
V +S + + ++ L Q++ DL + LL K++ +A+ D E+ ++
Sbjct: 802 VFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKI 861
Query: 127 QVETLKQKIMKLRKENEVLKRKFSHIEEGK 156
QV+ L Q++ K E E + + + E K
Sbjct: 862 QVQDLMQQLEKQNSEMEQKVKSLTQVYESK 891
Score = 34.7 bits (78), Expect = 0.088
Identities = 31/137 (22%), Positives = 61/137 (43%), Gaps = 14/137 (10%)
Query: 20 NEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQVHFEVESKYSSE 79
++ ++RLE KE + E +L+ I+ + + A L ++H + E
Sbjct: 1015 SDAVSRLETNQKEQIESLT--EVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQE 1072
Query: 80 IRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMTSNWQVETLKQK---IM 136
+ +LK ++ EK ++N+++ L++E +Q+ T N E LKQK +
Sbjct: 1073 VAELKQKILLFGCEKEEMNKEITWLKEE---------GVKQDTTLNELQEQLKQKSAHVN 1123
Query: 137 KLRKENEVLKRKFSHIE 153
L ++ LK +E
Sbjct: 1124 SLAQDETKLKAHLEKLE 1140
Score = 30.4 bits (67), Expect = 1.7
Identities = 35/163 (21%), Positives = 69/163 (41%), Gaps = 19/163 (11%)
Query: 11 ALKLLEEEYNEKIARLEAQVKESLHEKASYEATISQ-LHGDIAAHKNHMQILANRLDQVH 69
++ +L EEY K E ++++ + + T+ + L A K ++ A L Q
Sbjct: 937 SIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKE 996
Query: 70 FEVESKY-------SSEIRDLKDCLMAEQEE---------KNDLNRKMQLLEKELLLFKA 113
+ +K S+ I D L Q+E + +LN + + EK+L
Sbjct: 997 KQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAE 1056
Query: 114 KM--VDQQQEMTSNWQVETLKQKIMKLRKENEVLKRKFSHIEE 154
++ + + Q +V LKQKI+ E E + ++ + ++E
Sbjct: 1057 ELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKE 1099
>GCC1_MOUSE (Q9D4H2) GRIP and coiled-coil domain-containing protein
1 (Golgi coiled coil protein 1)
Length = 778
Score = 43.1 bits (100), Expect = 2e-04
Identities = 39/159 (24%), Positives = 76/159 (47%), Gaps = 23/159 (14%)
Query: 12 LKLLEEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQVH-- 69
LK+L+E+ E ARL Q + E++ + + +L + + Q L RL++
Sbjct: 215 LKVLQEQIAETKARLITQQHDRAQEQSDHALMLRELQKLLQEERTQRQDLELRLEETREA 274
Query: 70 -------------FEVESK-YSSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKM 115
FE+++K + E+ +LK L ++EKN + ++Q L++E K+
Sbjct: 275 LAGRAYAADQVEGFELQTKQLTREVEELKGELQTIRDEKNRPDPRLQELQQEAARLKSHF 334
Query: 116 VDQ-QQEMTSNWQVETLKQKIMKLRKENEVLKRKFSHIE 153
Q QQEM E +LR++++V +++ + +E
Sbjct: 335 QAQLQQEMRKTALAED------QLRQQSQVEEQRVAALE 367
Score = 29.6 bits (65), Expect = 2.8
Identities = 21/121 (17%), Positives = 56/121 (45%), Gaps = 11/121 (9%)
Query: 28 AQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQVHFEVESKYSSEIRDLKDCL 87
+++ + +H+ + AT++ + K+ M+ + + K + DL+D
Sbjct: 152 SEMDKRVHQLKTQLATLTSSLATVTQEKSRME--------ASYLADKKKMKQ--DLEDAN 201
Query: 88 MAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMTSNWQVETLK-QKIMKLRKENEVLK 146
+EE+ L +++L++++ KA+++ QQ + L +++ KL +E +
Sbjct: 202 KKAEEERGRLEGDLKVLQEQIAETKARLITQQHDRAQEQSDHALMLRELQKLLQEERTQR 261
Query: 147 R 147
+
Sbjct: 262 Q 262
>ANT1_ONCVO (P21249) Major antigen
Length = 2022
Score = 43.1 bits (100), Expect = 2e-04
Identities = 30/136 (22%), Positives = 69/136 (50%), Gaps = 6/136 (4%)
Query: 20 NEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQVHFEVESKYSSE 79
NEK+ L ++++++ + A + +L D+ + L +DQ S+ S+
Sbjct: 1554 NEKVRDLASRLQQTESKNADMKEDNDRLKKDLIKASTNEAELRRTIDQ-----NSRVVSD 1608
Query: 80 IRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMTSNW-QVETLKQKIMKL 138
+ LKD L + Q + ++ N + Q LE ELL+ ++++ D +Q + N ++ L++ +
Sbjct: 1609 NQILKDQLESAQNDLSNANNRKQQLENELLVVRSELRDLKQRFSDNANRIIDLQRHLTDA 1668
Query: 139 RKENEVLKRKFSHIEE 154
+ + L + + +E+
Sbjct: 1669 ENDKKRLTNRLNSLEK 1684
Score = 33.5 bits (75), Expect = 0.20
Identities = 32/151 (21%), Positives = 67/151 (44%), Gaps = 15/151 (9%)
Query: 6 QGHRRALKLLEEEYNE---KIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILA 62
+ ALK +EE + KIA+ E + + + + L D+ + + +L
Sbjct: 1453 RSQEEALKQRDEERSHMKLKIAKFEMEARGKEAQLRQLNELVRNLRKDLETAQGDLGVLH 1512
Query: 63 NRLDQVH---FEVESKYS---SEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMV 116
+ ++ + F +ESK SE + ++ + + E+N LN K++ L L ++K
Sbjct: 1513 DHEERWYAHKFHLESKLKDQESESQQIRLLVANFETERNSLNEKVRDLASRLQQTESKNA 1572
Query: 117 DQQQEMTSNWQVETLKQKIMKLRKENEVLKR 147
D +++ + LK+ ++K L+R
Sbjct: 1573 DMKEDN------DRLKKDLIKASTNEAELRR 1597
Score = 33.1 bits (74), Expect = 0.26
Identities = 30/157 (19%), Positives = 74/157 (47%), Gaps = 12/157 (7%)
Query: 9 RRALKLLEEEYNE---KIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRL 65
R L+ L++ +++ +I L+ + ++ ++K ++ L ++ + + +L
Sbjct: 1641 RSELRDLKQRFSDNANRIIDLQRHLTDAENDKKRLTNRLNSLEKTVSQQRTIETEIRQQL 1700
Query: 66 DQVHFEVESKYSSEIRDLKDCLMAEQEEKNDLNRKMQLLEK--ELLLFKAKMVDQQQEMT 123
E + +++RDL+ L + EK +N K LEK L+ + +++D+++
Sbjct: 1701 SLALNE-RNTLQNDLRDLQRRLARMETEKKIMNDKYDELEKIRASLIKRIELLDEEKRTM 1759
Query: 124 SN------WQVETLKQKIMKLRKENEVLKRKFSHIEE 154
N Q E ++ + L +EN+ L R + +++
Sbjct: 1760 ENILHETALQREAIESSLNALERENKELHRNCAQLQQ 1796
Score = 28.9 bits (63), Expect = 4.8
Identities = 31/141 (21%), Positives = 63/141 (43%), Gaps = 28/141 (19%)
Query: 20 NEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQVHFEVESKYSSE 79
N+++A+++A K L E H I + ++ + + + + +E+ +KY +E
Sbjct: 830 NDRLAKMDANFKIKLDETIKKSPAD---HETIKSRESKSEKIIVKHETKIYEI-NKYRAE 885
Query: 80 IR-------DLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMTSNWQVETLK 132
+ DL+ ++ Q+E N+ +R L E+ K K L+
Sbjct: 886 LEKLESDKDDLEKRIIGLQDELNEKDRDTDRLNAEIDDLKRK----------------LQ 929
Query: 133 QKIMKLRKENEVLKRKFSHIE 153
+I K+RKE ++ ++ HIE
Sbjct: 930 TEIEKVRKETTTVQERY-HIE 949
>IF2_AQUAE (O67825) Translation initiation factor IF-2
Length = 805
Score = 42.7 bits (99), Expect = 3e-04
Identities = 35/148 (23%), Positives = 68/148 (45%), Gaps = 6/148 (4%)
Query: 11 ALKLLEEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQVHF 70
A + EEE E++ +AQ + EK E + ++ K +++ +++
Sbjct: 56 AFGIKEEEEKEEVVTEQAQAPAEVEEKKEEEKKEEVIVEEVVEEKK-PEVIVEEIEEKKE 114
Query: 71 EVESKYSSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMV----DQQQEMTSNW 126
E E K + + + L+ E EK + ++ + +EKE K ++V ++++E
Sbjct: 115 EEEKKEEEKPKKSVEELIKEILEKKEKEKEKKKVEKERKEEKVRVVEVKKEERKEEKKEE 174
Query: 127 QVETLKQKIMKLRKENEVLKRKFSHIEE 154
+ E K KI +KE E++ RK H E
Sbjct: 175 KKEEEKPKIKMSKKEREIM-RKLEHAVE 201
>SBCC_CLOAB (Q97FK1) Nuclease sbcCD subunit C
Length = 1163
Score = 42.4 bits (98), Expect = 4e-04
Identities = 30/123 (24%), Positives = 65/123 (52%), Gaps = 5/123 (4%)
Query: 13 KLLEEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQVHFEV 72
K +E++ ++I L+++++E++ E TI L ++ + + L++ V
Sbjct: 697 KTVEKQCEKRIVDLKSELEEAIKEFNEVAYTIENLKAELKIQDFKFE-MKEILEKERVRV 755
Query: 73 ESKYSSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMTSNWQVETLK 132
E++ EI+DL++ L EK L K L++EL KA++ ++++ N ++E +K
Sbjct: 756 EAE--GEIKDLRNLLNIRHTEKEQLMDKCSRLKEELSKNKAEL--KEKDKIINEKIELIK 811
Query: 133 QKI 135
K+
Sbjct: 812 NKV 814
>GOA3_MOUSE (P55937) Golgi autoantigen, golgin subfamily A member 3
(Golgin-160) (Male-enhanced antigen-2) (MEA-2)
Length = 1447
Score = 42.4 bits (98), Expect = 4e-04
Identities = 37/161 (22%), Positives = 78/161 (47%), Gaps = 16/161 (9%)
Query: 5 EQGHRRA--------LKLLEEEYNEK---IARLEAQVKESLHEKASYEATISQLHGDIAA 53
E GH R L +++E K + L+A+V E + + I+Q ++A
Sbjct: 1157 EAGHNRRHFKAATLELSEVKKELQAKEHLVQTLQAEVDELQIQDGKHSQEIAQFQTELAE 1216
Query: 54 HKNHMQILANRLDQVHFEVESKYSSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKA 113
+ +Q+L +LD+ + S E+ DLK L ++ E L +++ L E++ K
Sbjct: 1217 ARTQLQLLQKKLDE-QMSQQPTGSQEMEDLKWELDQKEREIQSLKQQLDLTEQQ---GKK 1272
Query: 114 KMVDQQQEM-TSNWQVETLKQKIMKLRKENEVLKRKFSHIE 153
++ QQ + T ++E +++ + + +K+ +L+ K S ++
Sbjct: 1273 ELEGTQQTLQTIKSELEMVQEDLSETQKDKFMLQAKVSELK 1313
Score = 38.9 bits (89), Expect = 0.005
Identities = 29/127 (22%), Positives = 58/127 (44%), Gaps = 7/127 (5%)
Query: 22 KIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQVHFEVESKYSS--- 78
++ L + ++L EKA +A ++ L + A H + D + EV++ S
Sbjct: 376 QVEALSLEASQALQEKAELQAQLAALSTRLQAQVEHSHSSQQKQDSLSSEVDTLKQSCWD 435
Query: 79 ---EIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMTS-NWQVETLKQK 134
+ DL+ L A+ N +Q+ E++ AK+ D Q+ + S + V L+Q+
Sbjct: 436 LGRAMTDLQSMLEAKNASLASSNNDLQVAEEQYQRLMAKVEDMQRNILSKDNTVHDLRQQ 495
Query: 135 IMKLRKE 141
+ L+ +
Sbjct: 496 MTALQSQ 502
Score = 38.1 bits (87), Expect = 0.008
Identities = 36/141 (25%), Positives = 70/141 (49%), Gaps = 10/141 (7%)
Query: 12 LKLLEEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILAN-RLDQVHF 70
L L++E+ + I +L + +E+L K + + ++ A +Q A+ R D +HF
Sbjct: 668 LAALQQEHLDVIKQLTS-TQEALQAKGQSLDDLHTRYDELQARLEELQREADSREDAIHF 726
Query: 71 EVESKYSSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMT--SNWQV 128
K E+ L + + +K +L+R + LE++ + +Q++ SN QV
Sbjct: 727 LQNEKIVLEV-----ALQSAKSDKEELDRGARRLEEDTEETSGLLEQLRQDLAVKSN-QV 780
Query: 129 ETLKQKIMKLRKENEVLKRKF 149
E L+Q+ LRK+ + +K +F
Sbjct: 781 EHLQQETATLRKQMQKVKEQF 801
>NUM1_YEAST (Q00402) Nuclear migration protein NUM1
Length = 2748
Score = 41.6 bits (96), Expect = 7e-04
Identities = 40/144 (27%), Positives = 73/144 (49%), Gaps = 19/144 (13%)
Query: 10 RALKLLEEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQILANRLDQVH 69
R L+ E NE+I L+ Q+KESL +K I +L K+ M+ L + D ++
Sbjct: 112 RKLQSSNEAKNEQIKSLK-QIKESLSDK------IEELTNQ---KKSFMKELDSTKD-LN 160
Query: 70 FEVESKY---SSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMTS-- 124
+++ESK S E R LK+ ++ ND ++LL+ +L + + +++S
Sbjct: 161 WDLESKLTNLSMECRQLKELKKKTEKSWNDEKESLKLLKTDLEILTLTKNGMENDLSSQK 220
Query: 125 ---NWQVETLKQKIMKLRKENEVL 145
+ ++ LK++I+ L EN+ L
Sbjct: 221 LHYDKEISELKERILDLNNENDRL 244
>TANA_XENLA (Q01550) Tanabin
Length = 1744
Score = 41.2 bits (95), Expect = 0.001
Identities = 44/169 (26%), Positives = 75/169 (44%), Gaps = 34/169 (20%)
Query: 13 KLLEEE------YNEKIARLEAQVKESLH----EKASYEATISQLH--------GDIAAH 54
KLLEEE E++ +LEA++++ L EKA E I+ +A
Sbjct: 119 KLLEEETRAQIWLKERLGQLEAELEDILRDHEEEKALMEEEIASFSQRLENFRVAPVAFK 178
Query: 55 KNHMQILANRLDQVHFEVESKYSSEIRDLKDCLMAEQE------EKNDLNRKM-QLLEKE 107
+ A +L ++ +Y SE+ L+ L +E E+N NR + Q L+KE
Sbjct: 179 PVEVDDYARKLSEIWQGAVEEYKSEVSVLEAGLSESKENLRKVLEENKQNRLLLQSLDKE 238
Query: 108 LLLFKAKMVDQQQEMTSNWQVETLKQKIMKLRKENEVLKRKFSHIEEGK 156
L+ K + + ++ WQ + ++E E L+RK +E+ K
Sbjct: 239 LVSLKMRKEALEDLLSKQWQEQ---------KEEEEKLQRKAEALEQEK 278
>MYSJ_DICDI (P54697) Myosin IJ heavy chain
Length = 2245
Score = 41.2 bits (95), Expect = 0.001
Identities = 37/154 (24%), Positives = 79/154 (51%), Gaps = 23/154 (14%)
Query: 10 RALKLLEEEYN---EKIARL------EAQVKESLHE-KASYEATISQLHGDIAAHKNHMQ 59
R+L+ ++E+ N EK+ L EA+ K+ L + K + TIS+L +++ +H++
Sbjct: 971 RSLRTVQEQKNKLQEKLEELQWRLTSEAKRKQQLEDQKVKSDTTISEL----SSNNDHLE 1026
Query: 60 ILANRLDQVHFEVESKYSSEIRDLKDCLMAEQEEKNDLNRKMQL---LEKELLLFKAKMV 116
+ + + + E+++ S L +CL +E+ L+ +L LEK+L +
Sbjct: 1027 LQLSEIQLKYQELDNSNQSSQLQLSECLSKLEEQTQQLDHSSKLNKKLEKDL----SDQH 1082
Query: 117 DQQQEMTSNWQVETLKQKIMKLRKENEVLKRKFS 150
D +++ S Q +Q++ + ++++E L K S
Sbjct: 1083 DSIEKLQS--QFNETEQQLQQFKQQSEELSSKLS 1114
Score = 38.1 bits (87), Expect = 0.008
Identities = 35/161 (21%), Positives = 78/161 (47%), Gaps = 24/161 (14%)
Query: 9 RRALKLLEEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQI-------- 60
++ L+ L +E +E++ +L + E L + + I+QL ++ HK+ +QI
Sbjct: 1205 KQQLEQLVQEQSEQLIKLSS---EKLGSEEEAKKQINQLELELTDHKSKLQIQLQLTEQS 1261
Query: 61 ------LANRLDQVHFEVESKYSSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAK 114
L +L++ E + + E+ +K + ++EKN L ++ ++ E
Sbjct: 1262 NEKIKKLKGKLEEYQDE-KKQLQQELERIKQSKQSVEDEKNSLITQLTTVKFESTQVSTN 1320
Query: 115 MVDQQQEMTS-NWQVETLKQKIMKLR-----KENEVLKRKF 149
+ Q++++T+ +E L + I KL+ K++E+ K +F
Sbjct: 1321 VSHQKEKITTLKSTIEELNKSIGKLQAEQKNKDDEIRKIQF 1361
Score = 35.8 bits (81), Expect = 0.040
Identities = 30/157 (19%), Positives = 66/157 (41%), Gaps = 17/157 (10%)
Query: 1 MTFSEQGHRRALKLLEEEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQI 60
+ + E+GH + + ++++N +I L + L YE +L +++ K Q
Sbjct: 1536 LKYKERGHETSKQ--QDQFNMEIQSLRITNNDQLKSLQDYEQEKKKLKDKLSSSKQEAQ- 1592
Query: 61 LANRLDQVHFEVESKYSSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVD--- 117
R + + E + + + +++N + L K+ LL + +D
Sbjct: 1593 -QQRESIIKMDAELSAIKQHSQWVENSFTDMKQRNQELIESSALYKQQLLQQTSTIDSTI 1651
Query: 118 ----------QQQEMTSNWQVETLKQKIMKLRKENEV 144
QQQ TSN Q+ LK+++ +++ N++
Sbjct: 1652 KEKENEISKLQQQLETSNQQLHQLKEELNSMKQSNQL 1688
Score = 28.1 bits (61), Expect = 8.3
Identities = 27/136 (19%), Positives = 58/136 (41%), Gaps = 22/136 (16%)
Query: 17 EEYNEKIARLEAQVKESLHEKASYEATISQLHGDIAAHKNHMQ----ILANRLDQVHFEV 72
++Y + I RLE +VK+ K +E +A +N Q + + +
Sbjct: 1424 QQYKDTINRLENEVKQLTQLKERFENEFF-----VAKEQNSNQTQESVYLKEVTTQMQQN 1478
Query: 73 ESKYSSEIRDLKDCLMAEQEEKNDLNRKMQLLEKELLLFKAKMVDQQQEMTSNWQVETLK 132
+S+ E+ + K + +E+++L +++ L QQQ S+ Q+ +
Sbjct: 1479 QSRIERELEEKKQHITRIDDERDELKKQLTQL-------------QQQHEQSSTQLLLAQ 1525
Query: 133 QKIMKLRKENEVLKRK 148
++ +LRK+ K +
Sbjct: 1526 NELERLRKKELKYKER 1541
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.313 0.127 0.334
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,976,801
Number of Sequences: 164201
Number of extensions: 577342
Number of successful extensions: 4243
Number of sequences better than 10.0: 637
Number of HSP's better than 10.0 without gapping: 93
Number of HSP's successfully gapped in prelim test: 548
Number of HSP's that attempted gapping in prelim test: 3343
Number of HSP's gapped (non-prelim): 1371
length of query: 156
length of database: 59,974,054
effective HSP length: 101
effective length of query: 55
effective length of database: 43,389,753
effective search space: 2386436415
effective search space used: 2386436415
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Medicago: description of AC148819.6