BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC148755.12 - phase: 0
(440 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ALS2_MOUSE (Q920R0) Alsin (Amyotrophic lateral sclerosis protein... 108 3e-23
ALS2_HUMAN (Q96Q42) Alsin (Amyotrophic lateral sclerosis protein 2) 108 4e-23
TSA2_HUMAN (Q8WYR4) Testis-specific gene A2 (Male meiotic metaph... 100 1e-20
TSA2_MOUSE (Q8VIG3) Testis-specific gene A2 (Male meiotic metaph... 97 1e-19
JPH1_RABIT (Q9GKY8) Junctophilin 1 (Junctophilin type 1) (JP-1) ... 95 3e-19
JPH1_HUMAN (Q9HDC5) Junctophilin 1 (Junctophilin type 1) (JP-1) 94 7e-19
JPH3_HUMAN (Q8WXH2) Junctophilin 3 (Junctophilin type 3) (JP-3) 81 6e-15
JPH3_MOUSE (Q9ET77) Junctophilin 3 (Junctophilin type 3) (JP-3) 79 2e-14
JPH1_MOUSE (Q9ET80) Junctophilin 1 (Junctophilin type 1) (JP-1) 79 2e-14
JPH2_MOUSE (Q9ET78) Junctophilin 2 (Junctophilin type 2) (JP-2) 77 1e-13
JPH2_HUMAN (Q9BR39) Junctophilin 2 (Junctophilin type 2) (JP-2) 75 3e-13
JPH2_RABIT (Q9GKY7) Junctophilin 2 (Junctophilin type 2) (JP-2) 74 1e-12
JPH4_MOUSE (Q80WT0) Junctophilin 4 (Junctophilin-like 1 protein) 70 8e-12
JPH4_HUMAN (Q96JJ6) Junctophilin 4 (Junctophilin-like 1 protein) 70 8e-12
AKY1_HUMAN (Q9P2S6) Ankyrin repeat and MYND domain protein 1 (Te... 60 1e-08
SET7_MOUSE (Q8VHL1) Histone-lysine N-methyltransferase, H3 lysin... 54 6e-07
SET7_HUMAN (Q8WTS6) Histone-lysine N-methyltransferase, H3 lysin... 54 6e-07
ARP_PLAFA (P04931) Asparagine-rich protein (AG319) (ARP) (Fragment) 36 0.22
MUR2_ENTHR (P39046) Muramidase-2 precursor (EC 3.2.1.17) (1,4-be... 35 0.38
HKLB_LYCES (O22300) Homeobox protein knotted-1 like LET12 35 0.38
>ALS2_MOUSE (Q920R0) Alsin (Amyotrophic lateral sclerosis protein 2
homolog)
Length = 1651
Score = 108 bits (270), Expect = 3e-23
Identities = 66/199 (33%), Positives = 100/199 (50%), Gaps = 17/199 (8%)
Query: 172 YIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYRSANG-----DVSIGNWKTWK 226
Y G W + G G++ W G ++ G + NGL GYG YR N D +G+WK K
Sbjct: 1043 YDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKALNKEDHYVGHWKEGK 1102
Query: 227 MDDGRAIFDWANGDVFDGCMSNGLRHGFGVYRF-----ANGDVYIGNWKKDKMDGTGIMS 281
M G+ ++ +A+G+VF+GC + +RHG G+ R ++ ++IG W DK G G+
Sbjct: 1103 MC-GQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGVFD 1161
Query: 282 WVV-GDVFDGCWSNGLIHGYGVYRYANGDVDIGNFRSKLLHDNGKYTHSNGTIYEGDWVD 340
+ G+ + G W + + G GV G GNF + NG + TIYEG++ D
Sbjct: 1162 DITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGNGVLLSEDDTIYEGEFSD 1221
Query: 341 K-KVTEKGLKIWTLQNSHG 358
++ KG TL HG
Sbjct: 1222 DWTLSGKG----TLTMPHG 1236
Score = 82.0 bits (201), Expect = 3e-15
Identities = 58/219 (26%), Positives = 101/219 (45%), Gaps = 21/219 (9%)
Query: 108 ETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNWTCSDVFDGCRSIALIHGFGVYRYA 167
+T ++G W + +G GV ++ +G +Y+G + L G+G YR
Sbjct: 1035 DTRLKDATYDGRWLSGKPHGRGVLKWPDGKMYSGMF----------RNGLEDGYGEYRIP 1084
Query: 168 NVGV-----YIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYR-----SANGDV 217
N + Y+G WK+ + G G+ S+ +G+VF GC+ + + HG+G+ R S++ +
Sbjct: 1085 NKALNKEDHYVGHWKEGKMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSM 1144
Query: 218 SIGNWKTWKMDDGRAIFDWANGDVFDGCMSNGLRHGFGVYRFANGDVYIGNWKKDKMDGT 277
IG W K D G+ + G + + G GV G Y GN+ +KM G
Sbjct: 1145 FIGQWVMDKKAGYGVFDDITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGN 1204
Query: 278 GIMSWVVGDVFDGCWSNG-LIHGYGVYRYANGDVDIGNF 315
G++ +++G +S+ + G G +GD G F
Sbjct: 1205 GVLLSEDDTIYEGEFSDDWTLSGKGTLTMPHGDYIEGYF 1243
Score = 77.8 bits (190), Expect = 5e-14
Identities = 57/209 (27%), Positives = 90/209 (42%), Gaps = 15/209 (7%)
Query: 47 YVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGNGTQTYKNGG-----SYVGNWKNDK 101
Y G W+ G G+G+ P G Y G F G G N YVG+WK K
Sbjct: 1043 YDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKALNKEDHYVGHWKEGK 1102
Query: 102 KDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNWTCS--DVFDGCRSIALIH 159
G+G+ + A+G+VF GC+ ++ +G+G+ R +G T S +F G +
Sbjct: 1103 MCGQGVYSYASGEVFEGCFQDNMRHGHGLLR-------SGKLTSSSPSMFIGQWVMDKKA 1155
Query: 160 GFGVYRYANVG-VYIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYRSANGDVS 218
G+GV+ G Y+G+W+ G G++ G + G + G GV S + +
Sbjct: 1156 GYGVFDDITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGNGVLLSEDDTIY 1215
Query: 219 IGNWKTWKMDDGRAIFDWANGDVFDGCMS 247
G + G+ +GD +G S
Sbjct: 1216 EGEFSDDWTLSGKGTLTMPHGDYIEGYFS 1244
Score = 71.6 bits (174), Expect = 4e-12
Identities = 57/222 (25%), Positives = 86/222 (38%), Gaps = 49/222 (22%)
Query: 21 EGVYIGNIKDGLAHGKRKYTWSDGSI----------------------------YVGDWV 52
+ Y G G HG+ W DG + YVG W
Sbjct: 1040 DATYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKALNKEDHYVGHWK 1099
Query: 53 DGDKTGKGLFIQPSGDKYEGEFFGNRRHG-----NGTQTYKNGGSYVGNWKNDKKDGRGI 107
+G G+G++ SG+ +EG F N RHG +G T + ++G W DKK G G+
Sbjct: 1100 EGKMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGV 1159
Query: 108 -ETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNWTCSDVFDGCRSIALIHGFGVYRY 166
+ + G+ + G W +D G GV G Y GN+ + + G GV
Sbjct: 1160 FDDITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMM----------GNGVLLS 1209
Query: 167 ANVGVYIGIWKKH-ERDGLGIMSWDTGD----VFYGCWSNGL 203
+ +Y G + G G ++ GD F G W +G+
Sbjct: 1210 EDDTIYEGEFSDDWTLSGKGTLTMPHGDYIEGYFSGEWGSGI 1251
>ALS2_HUMAN (Q96Q42) Alsin (Amyotrophic lateral sclerosis protein 2)
Length = 1657
Score = 108 bits (269), Expect = 4e-23
Identities = 60/180 (33%), Positives = 92/180 (50%), Gaps = 12/180 (6%)
Query: 172 YIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYRSANG-----DVSIGNWKTWK 226
Y G W + G G++ W G ++ G + NGL GYG YR N D +G+WK K
Sbjct: 1049 YDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEGK 1108
Query: 227 MDDGRAIFDWANGDVFDGCMSNGLRHGFGVYRF-----ANGDVYIGNWKKDKMDGTGIMS 281
M G+ ++ +A+G+VF+GC + +RHG G+ R ++ ++IG W DK G G+
Sbjct: 1109 MC-GQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGVFD 1167
Query: 282 WVV-GDVFDGCWSNGLIHGYGVYRYANGDVDIGNFRSKLLHDNGKYTHSNGTIYEGDWVD 340
+ G+ + G W + + G GV G GNF + NG + TIYEG++ D
Sbjct: 1168 DITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGNGVLLSEDDTIYEGEFSD 1227
Score = 84.7 bits (208), Expect = 4e-16
Identities = 45/129 (34%), Positives = 68/129 (51%), Gaps = 25/129 (19%)
Query: 220 GNWKTWKMDDGRAIFDWANGDVFDGCMSNGLRHGFGVYRFANG-----DVYIGNWKKDKM 274
G W + K GR + W +G ++ G NGL G+G YR N D Y+G+WK+ KM
Sbjct: 1051 GRWLSGK-PHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEGKM 1109
Query: 275 DGTGIMSWVVGDVFDGCWSNGLIHGYGVYRYANGDVDIGNFRSKLLHDNGKYTHSNGTIY 334
G G+ S+ G+VF+GC+ + + HG+G+ R +GK T S+ +++
Sbjct: 1110 CGQGVYSYASGEVFEGCFQDNMRHGHGLLR------------------SGKLTSSSPSMF 1151
Query: 335 EGDWV-DKK 342
G WV DKK
Sbjct: 1152 IGQWVMDKK 1160
Score = 79.7 bits (195), Expect = 1e-14
Identities = 58/209 (27%), Positives = 90/209 (42%), Gaps = 15/209 (7%)
Query: 47 YVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGNGTQTYKNGGS-----YVGNWKNDK 101
Y G W+ G G+G+ P G Y G F G G N YVG+WK K
Sbjct: 1049 YDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEGK 1108
Query: 102 KDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNWTCS--DVFDGCRSIALIH 159
G+G+ + A+G+VF GC+ ++ +G+G+ R +G T S +F G +
Sbjct: 1109 MCGQGVYSYASGEVFEGCFQDNMRHGHGLLR-------SGKLTSSSPSMFIGQWVMDKKA 1161
Query: 160 GFGVYRYANVG-VYIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYRSANGDVS 218
G+GV+ G Y+G+W+ G G++ G + G + G GV S + +
Sbjct: 1162 GYGVFDDITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGNGVLLSEDDTIY 1221
Query: 219 IGNWKTWKMDDGRAIFDWANGDVFDGCMS 247
G + G+ NGD +G S
Sbjct: 1222 EGEFSDDWTLSGKGTLTMPNGDYIEGYFS 1250
Score = 72.8 bits (177), Expect = 2e-12
Identities = 71/271 (26%), Positives = 113/271 (41%), Gaps = 53/271 (19%)
Query: 92 SYVGNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFAN-----GDVYTGNWTCS 146
+Y G W + K GRG+ +G +++G + N GYG +R N D Y G+W
Sbjct: 1048 TYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHW--- 1104
Query: 147 DVFDGCRSIALIHGFGVYRYANVGVYIGIWKKHERDGLGI-----MSWDTGDVFYGCWSN 201
+ G GVY YA+ V+ G ++ + R G G+ ++ + +F G W
Sbjct: 1105 -------KEGKMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVM 1157
Query: 202 GLAHGYGVYRS-ANGDVSIGNWKTWKMDDGRAIFDWANGDVFDGCMSNG-LRHGFGVYRF 259
GYGV+ G+ +G W+ D C NG + FG+Y
Sbjct: 1158 DKKAGYGVFDDITRGEKYMGMWQD------------------DVCQGNGVVVTQFGLY-- 1197
Query: 260 ANGDVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNG-LIHGYGVYRYANGDVDIGNFRSK 318
Y GN+ +KM G G++ +++G +S+ + G G NGD G F +
Sbjct: 1198 -----YEGNFHLNKMMGNGVLLSEDDTIYEGEFSDDWTLSGKGTLTMPNGDYIEGYFSGE 1252
Query: 319 L---LHDNGKYTHSNGTIYEGDWVDKKVTEK 346
+ G T+ ++YE D KV K
Sbjct: 1253 WGSGIKITG--TYFKPSLYESDKDRPKVFRK 1281
Score = 72.4 bits (176), Expect = 2e-12
Identities = 57/222 (25%), Positives = 86/222 (38%), Gaps = 49/222 (22%)
Query: 21 EGVYIGNIKDGLAHGKRKYTWSDGSI----------------------------YVGDWV 52
+ Y G G HG+ W DG + YVG W
Sbjct: 1046 DATYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWK 1105
Query: 53 DGDKTGKGLFIQPSGDKYEGEFFGNRRHG-----NGTQTYKNGGSYVGNWKNDKKDGRGI 107
+G G+G++ SG+ +EG F N RHG +G T + ++G W DKK G G+
Sbjct: 1106 EGKMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGV 1165
Query: 108 -ETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNWTCSDVFDGCRSIALIHGFGVYRY 166
+ + G+ + G W +D G GV G Y GN+ + + G GV
Sbjct: 1166 FDDITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMM----------GNGVLLS 1215
Query: 167 ANVGVYIGIWKKH-ERDGLGIMSWDTGD----VFYGCWSNGL 203
+ +Y G + G G ++ GD F G W +G+
Sbjct: 1216 EDDTIYEGEFSDDWTLSGKGTLTMPNGDYIEGYFSGEWGSGI 1257
Score = 55.1 bits (131), Expect = 4e-07
Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 5/89 (5%)
Query: 265 YIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGVYRYAN-----GDVDIGNFRSKL 319
Y G W K G G++ W G ++ G + NGL GYG YR N D +G+++
Sbjct: 1049 YDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEGK 1108
Query: 320 LHDNGKYTHSNGTIYEGDWVDKKVTEKGL 348
+ G Y++++G ++EG + D GL
Sbjct: 1109 MCGQGVYSYASGEVFEGCFQDNMRHGHGL 1137
>TSA2_HUMAN (Q8WYR4) Testis-specific gene A2 (Male meiotic metaphase
chromosome-associated acidic protein) (Meichroacidin)
Length = 309
Score = 99.8 bits (247), Expect = 1e-20
Identities = 47/131 (35%), Positives = 69/131 (51%), Gaps = 11/131 (8%)
Query: 54 GDKTGKGLFIQPSGDKYEGEFFGNRRHGNGTQTYKNGGSYVGNWKNDKKDGRGIETLANG 113
G++ G+G P+GD YEG + +RHG G +KNG Y+G + +KK G+G +G
Sbjct: 28 GERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDG 87
Query: 114 DVFNGCWSNDFVYGYGVFRFANGDVYTGNWTCSDVFDGCRSIALIHGFGVYRYANVG-VY 172
+ G W+ND +G+GV+ + N D YTG W HG G Y YA G Y
Sbjct: 88 SRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQ----------RHGQGTYLYAETGSKY 137
Query: 173 IGIWKKHERDG 183
+G W +++G
Sbjct: 138 VGTWVNGQQEG 148
Score = 87.4 bits (215), Expect = 7e-17
Identities = 43/112 (38%), Positives = 61/112 (54%), Gaps = 1/112 (0%)
Query: 230 GRAIFDWANGDVFDGCMSNGLRHGFGVYRFANGDVYIGNWKKDKMDGTGIMSWVVGDVFD 289
GR NGD ++G G RHG G+Y+F NG YIG + ++K G G + G ++
Sbjct: 32 GRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYE 91
Query: 290 GCWSNGLIHGYGVYRYANGDVDIGNFRSKLLHDNGKYTHS-NGTIYEGDWVD 340
G W+N L HG+GVY Y N D G + + H G Y ++ G+ Y G WV+
Sbjct: 92 GEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVN 143
Score = 84.3 bits (207), Expect = 6e-16
Identities = 42/127 (33%), Positives = 64/127 (50%), Gaps = 2/127 (1%)
Query: 19 SDEGVYIGNIKD-GLAHGKRKYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGN 77
+D G Y G + G HG+ + +G Y G + G + G+G++ +G +Y GE+ N
Sbjct: 15 NDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRN 74
Query: 78 RRHGNGTQTYKNGGSYVGNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFA-NG 136
++HG GT Y +G Y G W ND + G G+ N D + G W +G G + +A G
Sbjct: 75 KKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETG 134
Query: 137 DVYTGNW 143
Y G W
Sbjct: 135 SKYVGTW 141
Score = 79.0 bits (193), Expect = 2e-14
Identities = 51/160 (31%), Positives = 70/160 (42%), Gaps = 3/160 (1%)
Query: 180 ERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYRSANGDVSIGNWKTWKMDDGRAIFDWANG 239
ER G G GD + G + G HG G+Y+ NG IG + K G+ F + +G
Sbjct: 29 ERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNK-KHGQGTFIYPDG 87
Query: 240 DVFDGCMSNGLRHGFGVYRFANGDVYIGNWKKDKMDGTGIMSWV-VGDVFDGCWSNGLIH 298
++G +N LRHG GVY + N D Y G W + G G + G + G W NG
Sbjct: 88 SRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQE 147
Query: 299 GYGVYRYANGDVDIGNFRSKLLHDNGKYTHSNGTIYEGDW 338
G + N G F +K GKY G G++
Sbjct: 148 GTAELIHLNHRYQ-GKFLNKNPVGPGKYVFDVGCEQHGEY 186
Score = 76.6 bits (187), Expect = 1e-13
Identities = 58/228 (25%), Positives = 89/228 (38%), Gaps = 38/228 (16%)
Query: 126 YGYGVFRFANGDVYTGNWTCSDVFDGCRSIALIHGFGVYRYANVGVYIGIWKKHERDGLG 185
+G G R NGD Y G++ HG G+Y++ N YIG + ++++ G G
Sbjct: 31 HGRGRARLPNGDTYEGSY----------EFGKRHGQGIYKFKNGARYIGEYVRNKKHGQG 80
Query: 186 IMSWDTGDVFYGCWSNGLAHGYGVYRSANGDVSIGNWKTWKMDDGRAIFDWANGDVFDGC 245
+ G + G W+N L HG+GVY N D G W +
Sbjct: 81 TFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQ------------------- 121
Query: 246 MSNGLRHGFGVYRFA-NGDVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGVYR 304
RHG G Y +A G Y+G W + +GT + + + G + N G G Y
Sbjct: 122 -----RHGQGTYLYAETGSKYVGTWVNGQQEGTAELIH-LNHRYQGKFLNKNPVGPGKYV 175
Query: 305 YANGDVDIGNFRSKLLHDNGKYTHSNGTIYEGDWVDKKVTEKGLKIWT 352
+ G G +R + + W ++TE L +WT
Sbjct: 176 FDVGCEQHGEYRLTDMERGEEEEEEELVTVVPKWKATQITE--LALWT 221
Score = 47.8 bits (112), Expect = 6e-05
Identities = 35/136 (25%), Positives = 53/136 (38%), Gaps = 25/136 (18%)
Query: 17 LYSDEGVYIGNIKDGLAHGKRKYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFG 76
+Y D Y G + L HG Y + + Y G+W F
Sbjct: 83 IYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEW-----------------------FA 119
Query: 77 NRRHGNGTQTY-KNGGSYVGNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFAN 135
++RHG GT Y + G YVG W N +++G E + + G + N G G + F
Sbjct: 120 HQRHGQGTYLYAETGSKYVGTWVNGQQEGTA-ELIHLNHRYQGKFLNKNPVGPGKYVFDV 178
Query: 136 GDVYTGNWTCSDVFDG 151
G G + +D+ G
Sbjct: 179 GCEQHGEYRLTDMERG 194
Score = 35.8 bits (81), Expect = 0.22
Identities = 22/68 (32%), Positives = 30/68 (43%)
Query: 284 VGDVFDGCWSNGLIHGYGVYRYANGDVDIGNFRSKLLHDNGKYTHSNGTIYEGDWVDKKV 343
+G+ G G HG G R NGD G++ H G Y NG Y G++V K
Sbjct: 17 IGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKK 76
Query: 344 TEKGLKIW 351
+G I+
Sbjct: 77 HGQGTFIY 84
>TSA2_MOUSE (Q8VIG3) Testis-specific gene A2 (Male meiotic metaphase
chromosome-associated acidic protein) (Meichroacidin)
Length = 301
Score = 96.7 bits (239), Expect = 1e-19
Identities = 49/131 (37%), Positives = 71/131 (53%), Gaps = 11/131 (8%)
Query: 54 GDKTGKGLFIQPSGDKYEGEFFGNRRHGNGTQTYKNGGSYVGNWKNDKKDGRGIETLANG 113
G++ G G P+GD YEG + +RHG GT +KNG Y G++ +KK G+G +G
Sbjct: 28 GERHGHGKARLPNGDTYEGSYEFGKRHGQGTYKFKNGARYTGDYVKNKKHGQGTFIYPDG 87
Query: 114 DVFNGCWSNDFVYGYGVFRFANGDVYTGNWTCSDVFDGCRSIALIHGFGVYRYANVG-VY 172
+ G W++D +G GV+ + N D YTG W F+ R HG G Y YA G Y
Sbjct: 88 SRYEGEWADDQRHGQGVYYYVNNDTYTGEW-----FNHQR-----HGQGTYLYAETGSKY 137
Query: 173 IGIWKKHERDG 183
+G W +++G
Sbjct: 138 VGTWVHGQQEG 148
Score = 86.3 bits (212), Expect = 1e-16
Identities = 45/145 (31%), Positives = 69/145 (47%), Gaps = 2/145 (1%)
Query: 19 SDEGVYIGNIKD-GLAHGKRKYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGN 77
+D G Y G + G HG K +G Y G + G + G+G + +G +Y G++ N
Sbjct: 15 NDLGEYEGERNEVGERHGHGKARLPNGDTYEGSYEFGKRHGQGTYKFKNGARYTGDYVKN 74
Query: 78 RRHGNGTQTYKNGGSYVGNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFA-NG 136
++HG GT Y +G Y G W +D++ G+G+ N D + G W N +G G + +A G
Sbjct: 75 KKHGQGTFIYPDGSRYEGEWADDQRHGQGVYYYVNNDTYTGEWFNHQRHGQGTYLYAETG 134
Query: 137 DVYTGNWTCSDVFDGCRSIALIHGF 161
Y G W I L H +
Sbjct: 135 SKYVGTWVHGQQEGAAELIHLNHRY 159
Score = 80.1 bits (196), Expect = 1e-14
Identities = 39/103 (37%), Positives = 55/103 (52%), Gaps = 1/103 (0%)
Query: 238 NGDVFDGCMSNGLRHGFGVYRFANGDVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLI 297
NGD ++G G RHG G Y+F NG Y G++ K+K G G + G ++G W++
Sbjct: 40 NGDTYEGSYEFGKRHGQGTYKFKNGARYTGDYVKNKKHGQGTFIYPDGSRYEGEWADDQR 99
Query: 298 HGYGVYRYANGDVDIGNFRSKLLHDNGKYTHS-NGTIYEGDWV 339
HG GVY Y N D G + + H G Y ++ G+ Y G WV
Sbjct: 100 HGQGVYYYVNNDTYTGEWFNHQRHGQGTYLYAETGSKYVGTWV 142
Score = 74.7 bits (182), Expect = 4e-13
Identities = 48/172 (27%), Positives = 77/172 (43%), Gaps = 4/172 (2%)
Query: 202 GLAHGYGVYRSANGDVSIGNWKTWKMDDGRAIFDWANGDVFDGCMSNGLRHGFGVYRFAN 261
G HG+G R NGD G+++ K G+ + + NG + G +HG G + + +
Sbjct: 28 GERHGHGKARLPNGDTYEGSYEFGKRH-GQGTYKFKNGARYTGDYVKNKKHGQGTFIYPD 86
Query: 262 GDVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGVYRYA-NGDVDIGNFRSKLL 320
G Y G W D+ G G+ +V D + G W N HG G Y YA G +G +
Sbjct: 87 GSRYEGEWADDQRHGQGVYYYVNNDTYTGEWFNHQRHGQGTYLYAETGSKYVGTWVHGQQ 146
Query: 321 HDNGKYTHSNGTIYEGDWVDKKVTEKGLKIWTLQ-NSHGSTSLQISNKGQSE 371
+ H N Y+G +++K G ++ + HG L + +G+ E
Sbjct: 147 EGAAELIHLNHR-YQGKFMNKNPVGPGKYVFDIGCEQHGEYRLTDTERGEEE 197
Score = 70.1 bits (170), Expect = 1e-11
Identities = 47/160 (29%), Positives = 68/160 (42%), Gaps = 3/160 (1%)
Query: 180 ERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYRSANGDVSIGNWKTWKMDDGRAIFDWANG 239
ER G G GD + G + G HG G Y+ NG G++ K G+ F + +G
Sbjct: 29 ERHGHGKARLPNGDTYEGSYEFGKRHGQGTYKFKNGARYTGDYVKNK-KHGQGTFIYPDG 87
Query: 240 DVFDGCMSNGLRHGFGVYRFANGDVYIGNWKKDKMDGTGIMSWV-VGDVFDGCWSNGLIH 298
++G ++ RHG GVY + N D Y G W + G G + G + G W +G
Sbjct: 88 SRYEGEWADDQRHGQGVYYYVNNDTYTGEWFNHQRHGQGTYLYAETGSKYVGTWVHGQQE 147
Query: 299 GYGVYRYANGDVDIGNFRSKLLHDNGKYTHSNGTIYEGDW 338
G + N G F +K GKY G G++
Sbjct: 148 GAAELIHLNHRYQ-GKFMNKNPVGPGKYVFDIGCEQHGEY 186
Score = 68.9 bits (167), Expect = 2e-11
Identities = 50/192 (26%), Positives = 74/192 (38%), Gaps = 36/192 (18%)
Query: 126 YGYGVFRFANGDVYTGNWTCSDVFDGCRSIALIHGFGVYRYANVGVYIGIWKKHERDGLG 185
+G+G R NGD Y G++ HG G Y++ N Y G + K+++ G G
Sbjct: 31 HGHGKARLPNGDTYEGSY----------EFGKRHGQGTYKFKNGARYTGDYVKNKKHGQG 80
Query: 186 IMSWDTGDVFYGCWSNGLAHGYGVYRSANGDVSIGNWKTWKMDDGRAIFDWANGDVFDGC 245
+ G + G W++ HG GVY N D G W
Sbjct: 81 TFIYPDGSRYEGEWADDQRHGQGVYYYVNNDTYTGEW----------------------- 117
Query: 246 MSNGLRHGFGVYRFA-NGDVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGVYR 304
N RHG G Y +A G Y+G W + +G + + + G + N G G Y
Sbjct: 118 -FNHQRHGQGTYLYAETGSKYVGTWVHGQQEGAAELIH-LNHRYQGKFMNKNPVGPGKYV 175
Query: 305 YANGDVDIGNFR 316
+ G G +R
Sbjct: 176 FDIGCEQHGEYR 187
Score = 46.2 bits (108), Expect = 2e-04
Identities = 34/136 (25%), Positives = 52/136 (38%), Gaps = 25/136 (18%)
Query: 17 LYSDEGVYIGNIKDGLAHGKRKYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFG 76
+Y D Y G D HG+ Y + + Y G+W F
Sbjct: 83 IYPDGSRYEGEWADDQRHGQGVYYYVNNDTYTGEW-----------------------FN 119
Query: 77 NRRHGNGTQTY-KNGGSYVGNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFAN 135
++RHG GT Y + G YVG W + +++G E + + G + N G G + F
Sbjct: 120 HQRHGQGTYLYAETGSKYVGTWVHGQQEG-AAELIHLNHRYQGKFMNKNPVGPGKYVFDI 178
Query: 136 GDVYTGNWTCSDVFDG 151
G G + +D G
Sbjct: 179 GCEQHGEYRLTDTERG 194
>JPH1_RABIT (Q9GKY8) Junctophilin 1 (Junctophilin type 1) (JP-1)
(Mitsugumin 72) (MG72)
Length = 662
Score = 95.1 bits (235), Expect = 3e-19
Identities = 88/342 (25%), Positives = 137/342 (39%), Gaps = 52/342 (15%)
Query: 18 YSDEGVYIGNIKDGLAHGKRKYTWSDGS-IYVGDWVDGDKTGKGLFIQPSGDKYEGEFFG 76
+ D G Y G ++G AHG T G Y G W G + G + PSG+ Y+G +
Sbjct: 8 FDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGG-YTWPSGNTYQGYWAQ 66
Query: 77 NRRHGNGTQTYKNGGSYVGNWKNDKKDGRGI-ETLANGDVFNGCWSNDFVYGYGVFRFAN 135
+RHG G +T K Y G W + K G+ ++L + G WSN GYGV + +
Sbjct: 67 GKRHGLGVET-KGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGD 125
Query: 136 GDVYTGNWTCSDVFDGCRSIALIHGFGVYRYANVGVYIGIWKKHERDGLGIMSWDT-GDV 194
G Y G W G R HG+GV + G+ I + S + G V
Sbjct: 126 GGTYQGQWA-----GGMR-----HGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSV 175
Query: 195 FYGCWS-----NGLAHGYGVYRSANGDVS-------------IGNWKTWKMDDGRAIFDW 236
+ + G G+ + A+ +++ +G+ K K + +I
Sbjct: 176 LHDAAAAADTPTGTRGGFVLNFHADAELAGKKKGGLFRRGSLLGSMKLRKSESKSSISSK 235
Query: 237 ANGDVFDGCMSNGLRHGFGVYRFANGDV------------------YIGNWKKDKMDGTG 278
+ D MS + + GDV Y+G WK DK +G G
Sbjct: 236 RSSVRSDAAMSR-ISSSDANSTISFGDVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFG 294
Query: 279 IMSWVVGDVFDGCWSNGLIHGYGVYRYANGDVDIGNFRSKLL 320
I G ++G W+N HGYG + +G + G +++ +L
Sbjct: 295 ISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNIL 336
Score = 79.7 bits (195), Expect = 1e-14
Identities = 76/344 (22%), Positives = 125/344 (36%), Gaps = 75/344 (21%)
Query: 38 KYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGN---GTQTYKNGGSYV 94
++ + DG Y G W +G G G+ P G +GE+ G+ HG G T+ +G +Y
Sbjct: 5 RFDFDDGGTYCGGWEEGKAHGHGICTGPKG---QGEYSGSWSHGFEVVGGYTWPSGNTYQ 61
Query: 95 GNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNWTCSDVFDGCRS 154
G W K+ G G+ET ++ G WS+ F YGV +
Sbjct: 62 GYWAQGKRHGLGVETKGKW-MYRGEWSHGFKGRYGVRQ---------------------- 98
Query: 155 IALIHGFGVYRYANVGVYIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYRSAN 214
Y G W +DG G+ ++ G + G W+ G+ HGYGV +S
Sbjct: 99 ----------SLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVP 148
Query: 215 GDVSIGNWKTWKMDDGRAIFDWANGDVFDGCMS-----NGLRHGFGVYRFANGDV----- 264
++ + + +NG V + G R GF + A+ ++
Sbjct: 149 YGMATVIRSPLRTSLASLRSEQSNGSVLHDAAAAADTPTGTRGGFVLNFHADAELAGKKK 208
Query: 265 --------YIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGVYRYANGDVD----- 311
+G+ K K + +S V + + + GDVD
Sbjct: 209 GGLFRRGSLLGSMKLRKSESKSSISSKRSSVRSDAAMSRISSSDANSTISFGDVDCDFCP 268
Query: 312 -------------IGNFRSKLLHDNGKYTHSNGTIYEGDWVDKK 342
+G +++ + G SNG YEG+W + K
Sbjct: 269 VEDHVDATTTETYMGEWKNDKRNGFGISERSNGMKYEGEWANNK 312
Score = 65.9 bits (159), Expect = 2e-10
Identities = 62/245 (25%), Positives = 91/245 (36%), Gaps = 44/245 (17%)
Query: 129 GVFRFANGDVYTGNWTCSDVFDGCRSIALIHGFGVYRYAN-VGVYIGIWKKHERDGLGIM 187
G F F +G Y G W HG G+ G Y G W H + +G
Sbjct: 4 GRFDFDDGGTYCGGWEEGKA----------HGHGICTGPKGQGEYSGSWS-HGFEVVGGY 52
Query: 188 SWDTGDVFYGCWSNGLAHGYGVYRSANGDVSIGNWKTWKMDDGRAIFDWANGDVFDGCMS 247
+W +G+ + G W+ G HG GV G W ++ G S
Sbjct: 53 TWPSGNTYQGYWAQGKRHGLGVETK-------GKW------------------MYRGEWS 87
Query: 248 NGLRHGFGVYR-FANGDVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGVYR-- 304
+G + +GV + Y G W DG G+ ++ G + G W+ G+ HGYGV +
Sbjct: 88 HGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSV 147
Query: 305 -YANGDVDIGNFRSKLLHDNGKYTHSNGTIYEGDWVDKKVTEKGLKIWTLQNSHGSTSLQ 363
Y V R+ L + + SNG++ D T G + + N H L
Sbjct: 148 PYGMATVIRSPLRTSLA--SLRSEQSNGSVLH-DAAAAADTPTGTRGGFVLNFHADAELA 204
Query: 364 ISNKG 368
KG
Sbjct: 205 GKKKG 209
Score = 50.4 bits (119), Expect = 9e-06
Identities = 23/62 (37%), Positives = 36/62 (57%)
Query: 92 SYVGNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNWTCSDVFDG 151
+Y+G WKNDK++G GI +NG + G W+N+ +GYG F +G G + + + G
Sbjct: 280 TYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRG 339
Query: 152 CR 153
R
Sbjct: 340 IR 341
Score = 49.7 bits (117), Expect = 2e-05
Identities = 20/54 (37%), Positives = 33/54 (61%)
Query: 47 YVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGNGTQTYKNGGSYVGNWKND 100
Y+G+W + + G G+ + +G KYEGE+ N+RHG G + +G G +KN+
Sbjct: 281 YMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNN 334
>JPH1_HUMAN (Q9HDC5) Junctophilin 1 (Junctophilin type 1) (JP-1)
Length = 661
Score = 94.0 bits (232), Expect = 7e-19
Identities = 87/342 (25%), Positives = 137/342 (39%), Gaps = 52/342 (15%)
Query: 18 YSDEGVYIGNIKDGLAHGKRKYTWSDGS-IYVGDWVDGDKTGKGLFIQPSGDKYEGEFFG 76
+ D G Y G ++G AHG T G Y G W G + G + PSG+ Y+G +
Sbjct: 8 FDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGG-YTWPSGNTYQGYWAQ 66
Query: 77 NRRHGNGTQTYKNGGSYVGNWKNDKKDGRGI-ETLANGDVFNGCWSNDFVYGYGVFRFAN 135
+RHG G +T K Y G W + K G+ ++L + G WSN GYGV + +
Sbjct: 67 GKRHGLGVET-KGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGD 125
Query: 136 GDVYTGNWTCSDVFDGCRSIALIHGFGVYRYANVGVYIGIWKKHERDGLGIMSWDT-GDV 194
G Y G W G R HG+GV + G+ I + S + G V
Sbjct: 126 GGTYQGQWA-----GGMR-----HGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSV 175
Query: 195 FYGCWSN-----GLAHGYGVYRSANGDVS-------------IGNWKTWKMDDGRAIFDW 236
+ + G G+ + A+ +++ +G+ K K + +I
Sbjct: 176 LHDAAAAADSPAGTRGGFVLNFHADAELAGKKKGGLFRRGSLLGSMKLRKSESKSSISSK 235
Query: 237 ANGDVFDGCMSNGLRHGFGVYRFANGDV------------------YIGNWKKDKMDGTG 278
+ D MS + + GDV Y+G WK DK +G G
Sbjct: 236 RSSVRSDAAMSR-ISSSDANSTISFGDVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFG 294
Query: 279 IMSWVVGDVFDGCWSNGLIHGYGVYRYANGDVDIGNFRSKLL 320
+ G ++G W+N HGYG + +G + G +++ +L
Sbjct: 295 VSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNIL 336
Score = 79.3 bits (194), Expect = 2e-14
Identities = 76/344 (22%), Positives = 125/344 (36%), Gaps = 75/344 (21%)
Query: 38 KYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGN---GTQTYKNGGSYV 94
++ + DG Y G W +G G G+ P G +GE+ G+ HG G T+ +G +Y
Sbjct: 5 RFDFDDGGTYCGGWEEGKAHGHGICTGPKG---QGEYSGSWSHGFEVVGGYTWPSGNTYQ 61
Query: 95 GNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNWTCSDVFDGCRS 154
G W K+ G G+ET ++ G WS+ F YGV +
Sbjct: 62 GYWAQGKRHGLGVETKGKW-MYRGEWSHGFKGRYGVRQ---------------------- 98
Query: 155 IALIHGFGVYRYANVGVYIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYRSAN 214
Y G W +DG G+ ++ G + G W+ G+ HGYGV +S
Sbjct: 99 ----------SLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVP 148
Query: 215 GDVSIGNWKTWKMDDGRAIFDWANGDVFDGCMS-----NGLRHGFGVYRFANGDV----- 264
++ + + +NG V + G R GF + A+ ++
Sbjct: 149 YGMATVIRSPLRTSLASLRSEQSNGSVLHDAAAAADSPAGTRGGFVLNFHADAELAGKKK 208
Query: 265 --------YIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGVYRYANGDVD----- 311
+G+ K K + +S V + + + GDVD
Sbjct: 209 GGLFRRGSLLGSMKLRKSESKSSISSKRSSVRSDAAMSRISSSDANSTISFGDVDCDFCP 268
Query: 312 -------------IGNFRSKLLHDNGKYTHSNGTIYEGDWVDKK 342
+G +++ + G SNG YEG+W + K
Sbjct: 269 VEDHVDATTTETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNK 312
Score = 67.8 bits (164), Expect = 5e-11
Identities = 43/143 (30%), Positives = 63/143 (43%), Gaps = 7/143 (4%)
Query: 185 GIMSWDTGDVFYGCWSNGLAHGYGVYRSANGDVSI-GNWKT-WKMDDGRAIFDWANGDVF 242
G +D G + G W G AHG+G+ G G+W +++ G + W +G+ +
Sbjct: 4 GRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGG---YTWPSGNTY 60
Query: 243 DGCMSNGLRHGFGVYRFANGDVYIGNWKKDKMDGTGI-MSWVVGDVFDGCWSNGLIHGYG 301
G + G RHG GV +Y G W G+ S ++G WSNGL GYG
Sbjct: 61 QGYWAQGKRHGLGVETKGKW-MYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYG 119
Query: 302 VYRYANGDVDIGNFRSKLLHDNG 324
V Y +G G + + H G
Sbjct: 120 VETYGDGGTYQGQWAGGMRHGYG 142
Score = 64.7 bits (156), Expect = 5e-10
Identities = 47/176 (26%), Positives = 68/176 (37%), Gaps = 38/176 (21%)
Query: 129 GVFRFANGDVYTGNWTCSDVFDGCRSIALIHGFGVYRYAN-VGVYIGIWKKHERDGLGIM 187
G F F +G Y G W HG G+ G Y G W H + +G
Sbjct: 4 GRFDFDDGGTYCGGWEEGKA----------HGHGICTGPKGQGEYSGSWS-HGFEVVGGY 52
Query: 188 SWDTGDVFYGCWSNGLAHGYGVYRSANGDVSIGNWKTWKMDDGRAIFDWANGDVFDGCMS 247
+W +G+ + G W+ G HG GV G W ++ G S
Sbjct: 53 TWPSGNTYQGYWAQGKRHGLGVETK-------GKW------------------MYRGEWS 87
Query: 248 NGLRHGFGVYR-FANGDVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGV 302
+G + +GV + Y G W DG G+ ++ G + G W+ G+ HGYGV
Sbjct: 88 HGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGV 143
Score = 50.1 bits (118), Expect = 1e-05
Identities = 22/62 (35%), Positives = 36/62 (57%)
Query: 92 SYVGNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNWTCSDVFDG 151
+Y+G WKNDK++G G+ +NG + G W+N+ +GYG F +G G + + + G
Sbjct: 280 TYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRG 339
Query: 152 CR 153
R
Sbjct: 340 IR 341
Score = 49.3 bits (116), Expect = 2e-05
Identities = 20/54 (37%), Positives = 33/54 (61%)
Query: 47 YVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGNGTQTYKNGGSYVGNWKND 100
Y+G+W + + G G+ + +G KYEGE+ N+RHG G + +G G +KN+
Sbjct: 281 YMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNN 334
Score = 36.6 bits (83), Expect = 0.13
Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 5/79 (6%)
Query: 285 GDVFDGCWSNGLIHGYGVYRYANGDVDIGNFRSKLLHDNGKYTHSNGTIYEGDWVDKK-- 342
G + G W G HG+G+ G + S G YT +G Y+G W K
Sbjct: 11 GGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRH 70
Query: 343 ---VTEKGLKIWTLQNSHG 358
V KG ++ + SHG
Sbjct: 71 GLGVETKGKWMYRGEWSHG 89
>JPH3_HUMAN (Q8WXH2) Junctophilin 3 (Junctophilin type 3) (JP-3)
Length = 748
Score = 80.9 bits (198), Expect = 6e-15
Identities = 51/153 (33%), Positives = 71/153 (46%), Gaps = 18/153 (11%)
Query: 38 KYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHG---NGTQTYKNGGSYV 94
++ + DG Y G W DG G G+ P G +GE+ G+ HG G T+ +G +Y
Sbjct: 6 RFNFDDGGSYCGGWEDGKAHGHGVCTGPKG---QGEYTGSWSHGFEVLGVYTWPSGNTYQ 62
Query: 95 GNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFA-NGDVYTGNWTCSDVFDGCR 153
G W K+ G G+E+ V+ G W++ F YGV A NG Y G W
Sbjct: 63 GTWAQGKRHGIGLESKGKW-VYKGEWTHGFKGRYGVRECAGNGAKYEGTW---------- 111
Query: 154 SIALIHGFGVYRYANVGVYIGIWKKHERDGLGI 186
S L G+G Y++ G Y G W R G G+
Sbjct: 112 SNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGV 144
Score = 73.2 bits (178), Expect = 1e-12
Identities = 61/214 (28%), Positives = 86/214 (39%), Gaps = 43/214 (20%)
Query: 129 GVFRFANGDVYTGNWTCSDVFDGCRSIALIHGFGVYRYAN-VGVYIGIWKKHERDGLGIM 187
G F F +G Y G W DG HG GV G Y G W H + LG+
Sbjct: 5 GRFNFDDGGSYCGGWE-----DG-----KAHGHGVCTGPKGQGEYTGSWS-HGFEVLGVY 53
Query: 188 SWDTGDVFYGCWSNGLAHGYGVYRSANGDVSIGNWKTWKMDDGRAIFDWANGDVFDGCMS 247
+W +G+ + G W+ G HG G+ S G W V+ G +
Sbjct: 54 TWPSGNTYQGTWAQGKRHGIGLE-------SKGKW------------------VYKGEWT 88
Query: 248 NGLRHGFGVYRFA-NGDVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGVYR-- 304
+G + +GV A NG Y G W DG G ++ G + G W G+ GYGV +
Sbjct: 89 HGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSV 148
Query: 305 -YANGDVDIGNFRSKLLHDNGKYTHSNGTIYEGD 337
Y V R+ + ++ + H+NGT D
Sbjct: 149 PYGMAAVIRSPLRTSI--NSLRSEHTNGTALHPD 180
Score = 72.0 bits (175), Expect = 3e-12
Identities = 45/137 (32%), Positives = 60/137 (42%), Gaps = 25/137 (18%)
Query: 18 YSDEGVYIGNIKDGLAHGKRKYTWSDGS-IYVGDWVDGDKTGKGLFIQPSGDKYEGEFFG 76
+ D G Y G +DG AHG T G Y G W G + G++ PSG+ Y+G +
Sbjct: 9 FDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEV-LGVYTWPSGNTYQGTWAQ 67
Query: 77 NRRHGNGTQT-----YK------------------NGGSYVGNWKNDKKDGRGIETLANG 113
+RHG G ++ YK NG Y G W N +DG G ET ++G
Sbjct: 68 GKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDG 127
Query: 114 DVFNGCWSNDFVYGYGV 130
+ G W GYGV
Sbjct: 128 GTYQGQWVGGMRQGYGV 144
Score = 70.1 bits (170), Expect = 1e-11
Identities = 53/203 (26%), Positives = 77/203 (37%), Gaps = 69/203 (33%)
Query: 83 GTQTYKNGGSYVGNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGN 142
G + +GGSY G W++ K G G+ T G YTG+
Sbjct: 5 GRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQ----------------------GEYTGS 42
Query: 143 WTCSDVFDGCRSIALIHGF---GVYRYANVGVYIGIWKKHERDGLGIMS---WDTGDVFY 196
W+ HGF GVY + + Y G W + +R G+G+ S W V+
Sbjct: 43 WS--------------HGFEVLGVYTWPSGNTYQGTWAQGKRHGIGLESKGKW----VYK 84
Query: 197 GCWSNGLAHGYGVYRSANGDVSIGNWKTWKMDDGRAIFDWANGDVFDGCMSNGLRHGFGV 256
G W++G YGV A NG ++G SNGL+ G+G
Sbjct: 85 GEWTHGFKGRYGVRECAG-----------------------NGAKYEGTWSNGLQDGYGT 121
Query: 257 YRFANGDVYIGNWKKDKMDGTGI 279
+++G Y G W G G+
Sbjct: 122 ETYSDGGTYQGQWVGGMRQGYGV 144
Score = 50.4 bits (119), Expect = 9e-06
Identities = 22/54 (40%), Positives = 33/54 (60%)
Query: 47 YVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGNGTQTYKNGGSYVGNWKND 100
YVG+W + ++G G+ + G KYEGE+ NRRHG G T+ +G G +K +
Sbjct: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQN 341
Score = 47.4 bits (111), Expect = 7e-05
Identities = 21/62 (33%), Positives = 35/62 (55%)
Query: 92 SYVGNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNWTCSDVFDG 151
+YVG WKNDK+ G G+ ++G + G W+++ +GYG F +G G + + + G
Sbjct: 287 TYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVGG 346
Query: 152 CR 153
R
Sbjct: 347 KR 348
Score = 46.6 bits (109), Expect = 1e-04
Identities = 18/58 (31%), Positives = 31/58 (53%)
Query: 263 DVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGVYRYANGDVDIGNFRSKLL 320
+ Y+G WK DK G G+ G ++G W++ HGYG + +G + G ++ +L
Sbjct: 286 ETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNIL 343
Score = 40.0 bits (92), Expect = 0.012
Identities = 17/52 (32%), Positives = 25/52 (47%)
Query: 172 YIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYRSANGDVSIGNWK 223
Y+G WK +R G G+ G + G W++ HGYG +G G +K
Sbjct: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYK 339
Score = 36.2 bits (82), Expect = 0.17
Identities = 24/90 (26%), Positives = 37/90 (40%), Gaps = 5/90 (5%)
Query: 274 MDGTGIMSWVVGDVFDGCWSNGLIHGYGVYRYANGDVDIGNFRSKLLHDNGKYTHSNGTI 333
M G ++ G + G W +G HG+GV G + S G YT +G
Sbjct: 1 MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNT 60
Query: 334 YEGDWVDKK-----VTEKGLKIWTLQNSHG 358
Y+G W K + KG ++ + +HG
Sbjct: 61 YQGTWAQGKRHGIGLESKGKWVYKGEWTHG 90
Score = 35.8 bits (81), Expect = 0.22
Identities = 16/60 (26%), Positives = 29/60 (47%)
Query: 68 DKYEGEFFGNRRHGNGTQTYKNGGSYVGNWKNDKKDGRGIETLANGDVFNGCWSNDFVYG 127
+ Y GE+ ++R G G +G Y G W ++++ G G T +G G + + + G
Sbjct: 286 ETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVG 345
Score = 34.3 bits (77), Expect = 0.65
Identities = 18/65 (27%), Positives = 31/65 (47%)
Query: 235 DWANGDVFDGCMSNGLRHGFGVYRFANGDVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSN 294
D + + G N R GFGV + ++G Y G W ++ G G M++ G +G +
Sbjct: 281 DATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQ 340
Query: 295 GLIHG 299
++ G
Sbjct: 341 NILVG 345
Score = 33.9 bits (76), Expect = 0.85
Identities = 18/54 (33%), Positives = 24/54 (44%)
Query: 24 YIGNIKDGLAHGKRKYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGN 77
Y+G K+ G SDG Y G+W + G G P G K EG++ N
Sbjct: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQN 341
Score = 32.3 bits (72), Expect = 2.5
Identities = 14/43 (32%), Positives = 22/43 (50%)
Query: 43 DGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGNGTQ 85
+G+ Y G W +G + G G G Y+G++ G R G G +
Sbjct: 103 NGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVR 145
Score = 30.8 bits (68), Expect = 7.2
Identities = 16/58 (27%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Query: 219 IGNWKTWKMDDGRAIFDWANGDVFDGCMSNGLRHGFGVYRFANGDVYIGNWKKDKMDG 276
+G WK K G + ++G ++G ++ RHG+G F +G G +K++ + G
Sbjct: 289 VGEWKNDKRS-GFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVG 345
>JPH3_MOUSE (Q9ET77) Junctophilin 3 (Junctophilin type 3) (JP-3)
Length = 744
Score = 79.3 bits (194), Expect = 2e-14
Identities = 50/153 (32%), Positives = 70/153 (45%), Gaps = 18/153 (11%)
Query: 38 KYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHG---NGTQTYKNGGSYV 94
++ + DG Y G W DG G G+ P G +GE+ G+ HG G T+ +G +Y
Sbjct: 6 RFNFDDGGSYCGGWEDGKAHGHGVCTGPKG---QGEYTGSWSHGFEVLGVYTWPSGNTYQ 62
Query: 95 GNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFR-FANGDVYTGNWTCSDVFDGCR 153
G W K+ G G+E+ V+ G W++ F YGV NG Y G W
Sbjct: 63 GTWAQGKRHGIGLESKGKW-VYKGEWTHGFKGRYGVRECTGNGAKYEGTW---------- 111
Query: 154 SIALIHGFGVYRYANVGVYIGIWKKHERDGLGI 186
S L G+G Y++ G Y G W R G G+
Sbjct: 112 SNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGV 144
Score = 72.0 bits (175), Expect = 3e-12
Identities = 45/137 (32%), Positives = 60/137 (42%), Gaps = 25/137 (18%)
Query: 18 YSDEGVYIGNIKDGLAHGKRKYTWSDGS-IYVGDWVDGDKTGKGLFIQPSGDKYEGEFFG 76
+ D G Y G +DG AHG T G Y G W G + G++ PSG+ Y+G +
Sbjct: 9 FDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEV-LGVYTWPSGNTYQGTWAQ 67
Query: 77 NRRHGNGTQT-----YK------------------NGGSYVGNWKNDKKDGRGIETLANG 113
+RHG G ++ YK NG Y G W N +DG G ET ++G
Sbjct: 68 GKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECTGNGAKYEGTWSNGLQDGYGTETYSDG 127
Query: 114 DVFNGCWSNDFVYGYGV 130
+ G W GYGV
Sbjct: 128 GTYQGQWVGGMRQGYGV 144
Score = 70.1 bits (170), Expect = 1e-11
Identities = 52/176 (29%), Positives = 70/176 (39%), Gaps = 38/176 (21%)
Query: 129 GVFRFANGDVYTGNWTCSDVFDGCRSIALIHGFGVYRYAN-VGVYIGIWKKHERDGLGIM 187
G F F +G Y G W DG HG GV G Y G W H + LG+
Sbjct: 5 GRFNFDDGGSYCGGWE-----DG-----KAHGHGVCTGPKGQGEYTGSWS-HGFEVLGVY 53
Query: 188 SWDTGDVFYGCWSNGLAHGYGVYRSANGDVSIGNWKTWKMDDGRAIFDWANGDVFDGCMS 247
+W +G+ + G W+ G HG G+ S G W V+ G +
Sbjct: 54 TWPSGNTYQGTWAQGKRHGIGLE-------SKGKW------------------VYKGEWT 88
Query: 248 NGLRHGFGVYRFA-NGDVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGV 302
+G + +GV NG Y G W DG G ++ G + G W G+ GYGV
Sbjct: 89 HGFKGRYGVRECTGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGV 144
Score = 69.7 bits (169), Expect = 1e-11
Identities = 54/203 (26%), Positives = 78/203 (37%), Gaps = 69/203 (33%)
Query: 83 GTQTYKNGGSYVGNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGN 142
G + +GGSY G W++ K G G+ T G YTG+
Sbjct: 5 GRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQ----------------------GEYTGS 42
Query: 143 WTCSDVFDGCRSIALIHGF---GVYRYANVGVYIGIWKKHERDGLGIMS---WDTGDVFY 196
W+ HGF GVY + + Y G W + +R G+G+ S W V+
Sbjct: 43 WS--------------HGFEVLGVYTWPSGNTYQGTWAQGKRHGIGLESKGKW----VYK 84
Query: 197 GCWSNGLAHGYGVYRSANGDVSIGNWKTWKMDDGRAIFDWANGDVFDGCMSNGLRHGFGV 256
G W++G YGV R G NG ++G SNGL+ G+G
Sbjct: 85 GEWTHGFKGRYGV-RECTG----------------------NGAKYEGTWSNGLQDGYGT 121
Query: 257 YRFANGDVYIGNWKKDKMDGTGI 279
+++G Y G W G G+
Sbjct: 122 ETYSDGGTYQGQWVGGMRQGYGV 144
Score = 50.8 bits (120), Expect = 7e-06
Identities = 22/54 (40%), Positives = 33/54 (60%)
Query: 47 YVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGNGTQTYKNGGSYVGNWKND 100
YVG+W + ++G G+ + G KYEGE+ NRRHG G T+ +G G +K +
Sbjct: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEWVSNRRHGYGCMTFPDGTKEEGKYKQN 341
Score = 46.6 bits (109), Expect = 1e-04
Identities = 21/62 (33%), Positives = 34/62 (53%)
Query: 92 SYVGNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNWTCSDVFDG 151
+YVG WKNDK+ G G+ ++G + G W ++ +GYG F +G G + + + G
Sbjct: 287 TYVGEWKNDKRSGFGVSQRSDGLKYEGEWVSNRRHGYGCMTFPDGTKEEGKYKQNVLVSG 346
Query: 152 CR 153
R
Sbjct: 347 KR 348
Score = 45.1 bits (105), Expect = 4e-04
Identities = 18/58 (31%), Positives = 30/58 (51%)
Query: 263 DVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGVYRYANGDVDIGNFRSKLL 320
+ Y+G WK DK G G+ G ++G W + HGYG + +G + G ++ +L
Sbjct: 286 ETYVGEWKNDKRSGFGVSQRSDGLKYEGEWVSNRRHGYGCMTFPDGTKEEGKYKQNVL 343
Score = 38.9 bits (89), Expect = 0.027
Identities = 17/52 (32%), Positives = 24/52 (45%)
Query: 172 YIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYRSANGDVSIGNWK 223
Y+G WK +R G G+ G + G W + HGYG +G G +K
Sbjct: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEWVSNRRHGYGCMTFPDGTKEEGKYK 339
Score = 36.2 bits (82), Expect = 0.17
Identities = 24/90 (26%), Positives = 37/90 (40%), Gaps = 5/90 (5%)
Query: 274 MDGTGIMSWVVGDVFDGCWSNGLIHGYGVYRYANGDVDIGNFRSKLLHDNGKYTHSNGTI 333
M G ++ G + G W +G HG+GV G + S G YT +G
Sbjct: 1 MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNT 60
Query: 334 YEGDWVDKK-----VTEKGLKIWTLQNSHG 358
Y+G W K + KG ++ + +HG
Sbjct: 61 YQGTWAQGKRHGIGLESKGKWVYKGEWTHG 90
Score = 35.4 bits (80), Expect = 0.29
Identities = 19/54 (35%), Positives = 25/54 (46%)
Query: 24 YIGNIKDGLAHGKRKYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGN 77
Y+G K+ G SDG Y G+WV + G G P G K EG++ N
Sbjct: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEWVSNRRHGYGCMTFPDGTKEEGKYKQN 341
Score = 33.9 bits (76), Expect = 0.85
Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 23 VYIGNIKDGLA--HGKRKYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRH 80
VY G G +G R+ T +G+ Y G W +G + G G G Y+G++ G R
Sbjct: 82 VYKGEWTHGFKGRYGVRECT-GNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQ 140
Query: 81 GNGTQ 85
G G +
Sbjct: 141 GYGVR 145
Score = 33.1 bits (74), Expect = 1.5
Identities = 14/46 (30%), Positives = 24/46 (51%)
Query: 68 DKYEGEFFGNRRHGNGTQTYKNGGSYVGNWKNDKKDGRGIETLANG 113
+ Y GE+ ++R G G +G Y G W ++++ G G T +G
Sbjct: 286 ETYVGEWKNDKRSGFGVSQRSDGLKYEGEWVSNRRHGYGCMTFPDG 331
Score = 32.3 bits (72), Expect = 2.5
Identities = 17/63 (26%), Positives = 30/63 (46%)
Query: 235 DWANGDVFDGCMSNGLRHGFGVYRFANGDVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSN 294
D + + G N R GFGV + ++G Y G W ++ G G M++ G +G +
Sbjct: 281 DATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWVSNRRHGYGCMTFPDGTKEEGKYKQ 340
Query: 295 GLI 297
++
Sbjct: 341 NVL 343
>JPH1_MOUSE (Q9ET80) Junctophilin 1 (Junctophilin type 1) (JP-1)
Length = 660
Score = 79.3 bits (194), Expect = 2e-14
Identities = 49/178 (27%), Positives = 74/178 (41%), Gaps = 39/178 (21%)
Query: 38 KYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGN---GTQTYKNGGSYV 94
++ + DG Y G W +G G G+ P G +GE+ G+ HG G T+ +G +Y
Sbjct: 5 RFDFDDGGTYCGGWEEGKAHGHGICTGPKG---QGEYSGSWSHGFEVVGVYTWPSGNTYQ 61
Query: 95 GNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNWTCSDVFDGCRS 154
G W K+ G G+ET ++ G WS+ F YGV +
Sbjct: 62 GYWAQGKRHGLGVETKGKW-MYRGEWSHGFKGRYGVRQ---------------------- 98
Query: 155 IALIHGFGVYRYANVGVYIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYRS 212
Y G W +DG G+ ++ G + G W+ G+ HGYGV +S
Sbjct: 99 ----------SLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQS 146
Score = 69.3 bits (168), Expect = 2e-11
Identities = 43/137 (31%), Positives = 61/137 (44%), Gaps = 25/137 (18%)
Query: 18 YSDEGVYIGNIKDGLAHGKRKYTWSDGS-IYVGDWVDGDKTGKGLFIQPSGDKYEGEFFG 76
+ D G Y G ++G AHG T G Y G W G + G++ PSG+ Y+G +
Sbjct: 8 FDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEV-VGVYTWPSGNTYQGYWAQ 66
Query: 77 NRRHGNGTQT-----YKNGGS------------------YVGNWKNDKKDGRGIETLANG 113
+RHG G +T Y+ S Y G W N +DG G+ET +G
Sbjct: 67 GKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDG 126
Query: 114 DVFNGCWSNDFVYGYGV 130
+ G W+ +GYGV
Sbjct: 127 GTYQGQWAGGMRHGYGV 143
Score = 69.3 bits (168), Expect = 2e-11
Identities = 43/142 (30%), Positives = 61/142 (42%), Gaps = 5/142 (3%)
Query: 185 GIMSWDTGDVFYGCWSNGLAHGYGVYRSANGDVSI-GNWKTWKMDDGRAIFDWANGDVFD 243
G +D G + G W G AHG+G+ G G+W G ++ W +G+ +
Sbjct: 4 GRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVG--VYTWPSGNTYQ 61
Query: 244 GCMSNGLRHGFGVYRFANGDVYIGNWKKDKMDGTGI-MSWVVGDVFDGCWSNGLIHGYGV 302
G + G RHG GV +Y G W G+ S ++G WSNGL GYGV
Sbjct: 62 GYWAQGKRHGLGVETKGKW-MYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGV 120
Query: 303 YRYANGDVDIGNFRSKLLHDNG 324
Y +G G + + H G
Sbjct: 121 ETYGDGGTYQGQWAGGMRHGYG 142
Score = 67.4 bits (163), Expect = 7e-11
Identities = 47/176 (26%), Positives = 69/176 (38%), Gaps = 38/176 (21%)
Query: 129 GVFRFANGDVYTGNWTCSDVFDGCRSIALIHGFGVYRYAN-VGVYIGIWKKHERDGLGIM 187
G F F +G Y G W HG G+ G Y G W H + +G+
Sbjct: 4 GRFDFDDGGTYCGGWEEGKA----------HGHGICTGPKGQGEYSGSWS-HGFEVVGVY 52
Query: 188 SWDTGDVFYGCWSNGLAHGYGVYRSANGDVSIGNWKTWKMDDGRAIFDWANGDVFDGCMS 247
+W +G+ + G W+ G HG GV G W ++ G S
Sbjct: 53 TWPSGNTYQGYWAQGKRHGLGVETK-------GKW------------------MYRGEWS 87
Query: 248 NGLRHGFGVYR-FANGDVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGV 302
+G + +GV + Y G W DG G+ ++ G + G W+ G+ HGYGV
Sbjct: 88 HGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGV 143
Score = 50.4 bits (119), Expect = 9e-06
Identities = 23/62 (37%), Positives = 36/62 (57%)
Query: 92 SYVGNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNWTCSDVFDG 151
+Y+G WKNDK++G GI +NG + G W+N+ +GYG F +G G + + + G
Sbjct: 280 TYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRG 339
Query: 152 CR 153
R
Sbjct: 340 IR 341
Score = 49.7 bits (117), Expect = 2e-05
Identities = 20/54 (37%), Positives = 33/54 (61%)
Query: 47 YVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGNGTQTYKNGGSYVGNWKND 100
Y+G+W + + G G+ + +G KYEGE+ N+RHG G + +G G +KN+
Sbjct: 281 YMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNN 334
Score = 48.5 bits (114), Expect = 3e-05
Identities = 20/58 (34%), Positives = 33/58 (56%)
Query: 263 DVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGVYRYANGDVDIGNFRSKLL 320
+ Y+G WK DK +G GI G ++G W+N HGYG + +G + G +++ +L
Sbjct: 279 ETYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNIL 336
Score = 42.0 bits (97), Expect = 0.003
Identities = 19/52 (36%), Positives = 26/52 (49%)
Query: 172 YIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYRSANGDVSIGNWK 223
Y+G WK +R+G GI G + G W+N HGYG +G G +K
Sbjct: 281 YMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYK 332
Score = 40.8 bits (94), Expect = 0.007
Identities = 18/58 (31%), Positives = 29/58 (49%)
Query: 68 DKYEGEFFGNRRHGNGTQTYKNGGSYVGNWKNDKKDGRGIETLANGDVFNGCWSNDFV 125
+ Y GE+ ++R+G G NG Y G W N+K+ G G +G G + N+ +
Sbjct: 279 ETYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNIL 336
Score = 36.6 bits (83), Expect = 0.13
Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 5/79 (6%)
Query: 285 GDVFDGCWSNGLIHGYGVYRYANGDVDIGNFRSKLLHDNGKYTHSNGTIYEGDWVDKK-- 342
G + G W G HG+G+ G + S G YT +G Y+G W K
Sbjct: 11 GGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGVYTWPSGNTYQGYWAQGKRH 70
Query: 343 ---VTEKGLKIWTLQNSHG 358
V KG ++ + SHG
Sbjct: 71 GLGVETKGKWMYRGEWSHG 89
Score = 35.8 bits (81), Expect = 0.22
Identities = 18/63 (28%), Positives = 29/63 (45%)
Query: 235 DWANGDVFDGCMSNGLRHGFGVYRFANGDVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSN 294
D + + G N R+GFG+ +NG Y G W +K G G + G +G + N
Sbjct: 274 DATTTETYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKN 333
Query: 295 GLI 297
++
Sbjct: 334 NIL 336
Score = 34.7 bits (78), Expect = 0.50
Identities = 17/54 (31%), Positives = 27/54 (49%)
Query: 24 YIGNIKDGLAHGKRKYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGN 77
Y+G K+ +G S+G Y G+W + + G G + P G K EG++ N
Sbjct: 281 YMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNN 334
Score = 33.9 bits (76), Expect = 0.85
Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 219 IGNWKTWKMDDGRAIFDWANGDVFDGCMSNGLRHGFGVYRFANGDVYIGNWKKD 272
+G WK K + G I + +NG ++G +N RHG+G F +G G +K +
Sbjct: 282 MGEWKNDKRN-GFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNN 334
>JPH2_MOUSE (Q9ET78) Junctophilin 2 (Junctophilin type 2) (JP-2)
Length = 696
Score = 76.6 bits (187), Expect = 1e-13
Identities = 54/183 (29%), Positives = 76/183 (41%), Gaps = 49/183 (26%)
Query: 38 KYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHG---NGTQTYKNGGSYV 94
++ + DG Y G W G G GL P G +GE+ G+ G G T+ +G ++
Sbjct: 5 RFDFDDGGAYCGGWEGGKAHGHGLCTGPKG---QGEYSGSWNFGFEVAGVYTWPSGNTFE 61
Query: 95 GNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNWTCSDVFDGCRS 154
G W K+ G GIET G W +Y G WT
Sbjct: 62 GYWSQGKRHGLGIET-------KGRW-----------------LYKGEWT---------- 87
Query: 155 IALIHGF----GVYRYANVGV-YIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGV 209
HGF G+ + N G Y G W +DG G ++ G + G ++NG+ HGYGV
Sbjct: 88 ----HGFKGRYGIRQSTNSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGV 143
Query: 210 YRS 212
+S
Sbjct: 144 RQS 146
Score = 70.5 bits (171), Expect = 8e-12
Identities = 50/176 (28%), Positives = 74/176 (41%), Gaps = 31/176 (17%)
Query: 185 GIMSWDTGDVFYGCWSNGLAHGYGVYRSANGDVSI-GNWKTWKMDDGRAIFDWANGDVFD 243
G +D G + G W G AHG+G+ G G+W G ++ W +G+ F+
Sbjct: 4 GRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAG--VYTWPSGNTFE 61
Query: 244 GCMSNGLRHGFGVY-----------------RFA------NGDVYIGNWKKDKMDGTGIM 280
G S G RHG G+ R+ +G Y G W DG G
Sbjct: 62 GYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSTNSGAKYEGTWNNGLQDGYGTE 121
Query: 281 SWVVGDVFDGCWSNGLIHGYGVYR---YANGDVDIGNFRSKLLHDNGKYTHSNGTI 333
++ G + G ++NG+ HGYGV + Y V R+ L + + HSNGT+
Sbjct: 122 TYADGGTYQGQFTNGMRHGYGVRQSVPYGMAVVVRSPLRTSL--SSLRSEHSNGTV 175
Score = 69.7 bits (169), Expect = 1e-11
Identities = 45/137 (32%), Positives = 62/137 (44%), Gaps = 25/137 (18%)
Query: 18 YSDEGVYIGNIKDGLAHGKRKYTWSDGS-IYVGDWVDGDKTGKGLFIQPSGDKYEGEFFG 76
+ D G Y G + G AHG T G Y G W G + G++ PSG+ +EG +
Sbjct: 8 FDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVA-GVYTWPSGNTFEGYWSQ 66
Query: 77 NRRHGNGTQT-----YK------------------NGGSYVGNWKNDKKDGRGIETLANG 113
+RHG G +T YK +G Y G W N +DG G ET A+G
Sbjct: 67 GKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSTNSGAKYEGTWNNGLQDGYGTETYADG 126
Query: 114 DVFNGCWSNDFVYGYGV 130
+ G ++N +GYGV
Sbjct: 127 GTYQGQFTNGMRHGYGV 143
Score = 68.2 bits (165), Expect = 4e-11
Identities = 50/176 (28%), Positives = 73/176 (41%), Gaps = 38/176 (21%)
Query: 83 GTQTYKNGGSYVGNWKNDKKDGRGIETLANGD-VFNGCWSNDFVYGYGVFRFANGDVYTG 141
G + +GG+Y G W+ K G G+ T G ++G W+ F F VYT
Sbjct: 4 GRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWN---------FGFEVAGVYT- 53
Query: 142 NWTCSDVFDGCRSIALIHGFGVYRYANVGVYIGIWKKHERDGLGI-MSWDTGDVFYGCWS 200
W + F+G S HG G+ +Y G W + GI S ++G + G W+
Sbjct: 54 -WPSGNTFEGYWSQGKRHGLGIETKGR-WLYKGEWTHGFKGRYGIRQSTNSGAKYEGTWN 111
Query: 201 NGLAHGYGVYRSANGDVSIGNWKTWKMDDGRAIFDWANGDVFDGCMSNGLRHGFGV 256
NGL GYG +A+G + G +NG+RHG+GV
Sbjct: 112 NGLQDGYGTET------------------------YADGGTYQGQFTNGMRHGYGV 143
Score = 44.3 bits (103), Expect = 6e-04
Identities = 19/54 (35%), Positives = 33/54 (60%)
Query: 47 YVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGNGTQTYKNGGSYVGNWKND 100
Y+G+W + ++G G+ + SG +YEGE+ N RHG G T +G G ++++
Sbjct: 285 YMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGRTTLPDGHREEGKYRHN 338
Score = 44.3 bits (103), Expect = 6e-04
Identities = 20/58 (34%), Positives = 30/58 (51%)
Query: 263 DVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGVYRYANGDVDIGNFRSKLL 320
+ Y+G WK DK G G+ G ++G W + L HGYG +G + G +R +L
Sbjct: 283 ETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGRTTLPDGHREEGKYRHNVL 340
Score = 41.2 bits (95), Expect = 0.005
Identities = 17/52 (32%), Positives = 29/52 (55%)
Query: 92 SYVGNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNW 143
+Y+G WKNDK+ G G+ ++G + G W ++ +GYG +G G +
Sbjct: 284 TYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGRTTLPDGHREEGKY 335
Score = 38.1 bits (87), Expect = 0.045
Identities = 17/52 (32%), Positives = 26/52 (49%)
Query: 172 YIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYRSANGDVSIGNWK 223
Y+G WK +R G G+ +G + G W + L HGYG +G G ++
Sbjct: 285 YMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGRTTLPDGHREEGKYR 336
Score = 35.0 bits (79), Expect = 0.38
Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 34 HGKRKYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGNGTQ 85
+G R+ T + G+ Y G W +G + G G G Y+G+F RHG G +
Sbjct: 94 YGIRQST-NSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVR 144
Score = 32.3 bits (72), Expect = 2.5
Identities = 15/46 (32%), Positives = 24/46 (51%)
Query: 68 DKYEGEFFGNRRHGNGTQTYKNGGSYVGNWKNDKKDGRGIETLANG 113
+ Y GE+ ++R G G +G Y G W ++ + G G TL +G
Sbjct: 283 ETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGRTTLPDG 328
Score = 32.0 bits (71), Expect = 3.2
Identities = 20/79 (25%), Positives = 32/79 (40%), Gaps = 5/79 (6%)
Query: 285 GDVFDGCWSNGLIHGYGVYRYANGDVDIGNFRSKLLHDNGKYTHSNGTIYEGDWVDKK-- 342
G + G W G HG+G+ G + + G YT +G +EG W K
Sbjct: 11 GGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEGYWSQGKRH 70
Query: 343 ---VTEKGLKIWTLQNSHG 358
+ KG ++ + +HG
Sbjct: 71 GLGIETKGRWLYKGEWTHG 89
Score = 30.8 bits (68), Expect = 7.2
Identities = 17/54 (31%), Positives = 25/54 (45%)
Query: 24 YIGNIKDGLAHGKRKYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGN 77
Y+G K+ G S G Y G+W+D + G G P G + EG++ N
Sbjct: 285 YMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGRTTLPDGHREEGKYRHN 338
>JPH2_HUMAN (Q9BR39) Junctophilin 2 (Junctophilin type 2) (JP-2)
Length = 696
Score = 75.1 bits (183), Expect = 3e-13
Identities = 53/183 (28%), Positives = 77/183 (41%), Gaps = 49/183 (26%)
Query: 38 KYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHG---NGTQTYKNGGSYV 94
++ + DG Y G W G G GL P G +GE+ G+ G G T+ +G ++
Sbjct: 5 RFDFDDGGAYCGGWEGGKAHGHGLCTGPKG---QGEYSGSWNFGFEVAGVYTWPSGNTFE 61
Query: 95 GNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNWTCSDVFDGCRS 154
G W K+ G GIET G W +Y G WT
Sbjct: 62 GYWSQGKRHGLGIET-------KGRW-----------------LYKGEWT---------- 87
Query: 155 IALIHGF----GVYRYANVGV-YIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGV 209
HGF G+ + ++ G Y G W +DG G ++ G + G ++NG+ HGYGV
Sbjct: 88 ----HGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGV 143
Query: 210 YRS 212
+S
Sbjct: 144 RQS 146
Score = 71.2 bits (173), Expect = 5e-12
Identities = 49/176 (27%), Positives = 73/176 (40%), Gaps = 31/176 (17%)
Query: 185 GIMSWDTGDVFYGCWSNGLAHGYGVYRSANGDVSI-GNWKTWKMDDGRAIFDWANGDVFD 243
G +D G + G W G AHG+G+ G G+W G ++ W +G+ F+
Sbjct: 4 GRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAG--VYTWPSGNTFE 61
Query: 244 GCMSNGLRHGFGV-----------------------YRFANGDVYIGNWKKDKMDGTGIM 280
G S G RHG G+ ++G Y G W DG G
Sbjct: 62 GYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTE 121
Query: 281 SWVVGDVFDGCWSNGLIHGYGVYR---YANGDVDIGNFRSKLLHDNGKYTHSNGTI 333
++ G + G ++NG+ HGYGV + Y V R+ L + + HSNGT+
Sbjct: 122 TYADGGTYQGQFTNGMRHGYGVRQSVPYGMAVVVRSPLRTSL--SSLRSEHSNGTV 175
Score = 69.7 bits (169), Expect = 1e-11
Identities = 45/137 (32%), Positives = 62/137 (44%), Gaps = 25/137 (18%)
Query: 18 YSDEGVYIGNIKDGLAHGKRKYTWSDGS-IYVGDWVDGDKTGKGLFIQPSGDKYEGEFFG 76
+ D G Y G + G AHG T G Y G W G + G++ PSG+ +EG +
Sbjct: 8 FDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVA-GVYTWPSGNTFEGYWSQ 66
Query: 77 NRRHGNGTQT-----YK------------------NGGSYVGNWKNDKKDGRGIETLANG 113
+RHG G +T YK +G Y G W N +DG G ET A+G
Sbjct: 67 GKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADG 126
Query: 114 DVFNGCWSNDFVYGYGV 130
+ G ++N +GYGV
Sbjct: 127 GTYQGQFTNGMRHGYGV 143
Score = 67.4 bits (163), Expect = 7e-11
Identities = 50/176 (28%), Positives = 72/176 (40%), Gaps = 38/176 (21%)
Query: 83 GTQTYKNGGSYVGNWKNDKKDGRGIETLANGD-VFNGCWSNDFVYGYGVFRFANGDVYTG 141
G + +GG+Y G W+ K G G+ T G ++G W+ F F VYT
Sbjct: 4 GRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWN---------FGFEVAGVYT- 53
Query: 142 NWTCSDVFDGCRSIALIHGFGVYRYANVGVYIGIWKKHERDGLGI-MSWDTGDVFYGCWS 200
W + F+G S HG G+ +Y G W + GI S +G + G W+
Sbjct: 54 -WPSGNTFEGYWSQGKRHGLGIETKGR-WLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWN 111
Query: 201 NGLAHGYGVYRSANGDVSIGNWKTWKMDDGRAIFDWANGDVFDGCMSNGLRHGFGV 256
NGL GYG +A+G + G +NG+RHG+GV
Sbjct: 112 NGLQDGYGTET------------------------YADGGTYQGQFTNGMRHGYGV 143
Score = 45.1 bits (105), Expect = 4e-04
Identities = 20/58 (34%), Positives = 30/58 (51%)
Query: 263 DVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGVYRYANGDVDIGNFRSKLL 320
+ Y+G WK DK G G+ G ++G W + L HGYG +G + G +R +L
Sbjct: 289 ETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHNVL 346
Score = 44.3 bits (103), Expect = 6e-04
Identities = 19/54 (35%), Positives = 33/54 (60%)
Query: 47 YVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGNGTQTYKNGGSYVGNWKND 100
Y+G+W + ++G G+ + SG +YEGE+ N RHG G T +G G ++++
Sbjct: 291 YMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHN 344
Score = 42.0 bits (97), Expect = 0.003
Identities = 17/52 (32%), Positives = 29/52 (55%)
Query: 92 SYVGNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNW 143
+Y+G WKNDK+ G G+ ++G + G W ++ +GYG +G G +
Sbjct: 290 TYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKY 341
Score = 38.9 bits (89), Expect = 0.027
Identities = 17/52 (32%), Positives = 26/52 (49%)
Query: 172 YIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYRSANGDVSIGNWK 223
Y+G WK +R G G+ +G + G W + L HGYG +G G ++
Sbjct: 291 YMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYR 342
Score = 33.1 bits (74), Expect = 1.5
Identities = 15/46 (32%), Positives = 24/46 (51%)
Query: 68 DKYEGEFFGNRRHGNGTQTYKNGGSYVGNWKNDKKDGRGIETLANG 113
+ Y GE+ ++R G G +G Y G W ++ + G G TL +G
Sbjct: 289 ETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDG 334
Score = 32.0 bits (71), Expect = 3.2
Identities = 20/79 (25%), Positives = 32/79 (40%), Gaps = 5/79 (6%)
Query: 285 GDVFDGCWSNGLIHGYGVYRYANGDVDIGNFRSKLLHDNGKYTHSNGTIYEGDWVDKK-- 342
G + G W G HG+G+ G + + G YT +G +EG W K
Sbjct: 11 GGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEGYWSQGKRH 70
Query: 343 ---VTEKGLKIWTLQNSHG 358
+ KG ++ + +HG
Sbjct: 71 GLGIETKGRWLYKGEWTHG 89
Score = 31.2 bits (69), Expect = 5.5
Identities = 17/54 (31%), Positives = 25/54 (45%)
Query: 24 YIGNIKDGLAHGKRKYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGN 77
Y+G K+ G S G Y G+W+D + G G P G + EG++ N
Sbjct: 291 YMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHN 344
>JPH2_RABIT (Q9GKY7) Junctophilin 2 (Junctophilin type 2) (JP-2)
Length = 694
Score = 73.6 bits (179), Expect = 1e-12
Identities = 53/183 (28%), Positives = 75/183 (40%), Gaps = 49/183 (26%)
Query: 38 KYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHG---NGTQTYKNGGSYV 94
++ + DG Y G W G G GL P G +GE+ G+ G G T+ +G ++
Sbjct: 5 RFDFDDGGAYCGGWEGGKAHGHGLCTGPKG---QGEYSGSWNFGFEVAGVYTWPSGNTFE 61
Query: 95 GNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNWTCSDVFDGCRS 154
G W K+ G GIET G W +Y G WT
Sbjct: 62 GYWSQGKRHGLGIET-------KGRW-----------------LYKGEWT---------- 87
Query: 155 IALIHGF----GVYRYANVGV-YIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGV 209
HGF G + + G Y G W +DG G ++ G + G ++NG+ HGYGV
Sbjct: 88 ----HGFKGRYGTRQSTSSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGV 143
Query: 210 YRS 212
+S
Sbjct: 144 RQS 146
Score = 71.2 bits (173), Expect = 5e-12
Identities = 49/176 (27%), Positives = 73/176 (40%), Gaps = 31/176 (17%)
Query: 185 GIMSWDTGDVFYGCWSNGLAHGYGVYRSANGDVSI-GNWKTWKMDDGRAIFDWANGDVFD 243
G +D G + G W G AHG+G+ G G+W G ++ W +G+ F+
Sbjct: 4 GRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAG--VYTWPSGNTFE 61
Query: 244 GCMSNGLRHGFGV-----------------------YRFANGDVYIGNWKKDKMDGTGIM 280
G S G RHG G+ ++G Y G W DG G
Sbjct: 62 GYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGTRQSTSSGAKYEGTWNNGLQDGYGTE 121
Query: 281 SWVVGDVFDGCWSNGLIHGYGVYR---YANGDVDIGNFRSKLLHDNGKYTHSNGTI 333
++ G + G ++NG+ HGYGV + Y V R+ L + + HSNGT+
Sbjct: 122 TYADGGTYQGQFTNGMRHGYGVRQSVPYGMAVVVRSPLRTSL--SSLRSEHSNGTV 175
Score = 69.7 bits (169), Expect = 1e-11
Identities = 45/137 (32%), Positives = 62/137 (44%), Gaps = 25/137 (18%)
Query: 18 YSDEGVYIGNIKDGLAHGKRKYTWSDGS-IYVGDWVDGDKTGKGLFIQPSGDKYEGEFFG 76
+ D G Y G + G AHG T G Y G W G + G++ PSG+ +EG +
Sbjct: 8 FDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVA-GVYTWPSGNTFEGYWSQ 66
Query: 77 NRRHGNGTQT-----YK------------------NGGSYVGNWKNDKKDGRGIETLANG 113
+RHG G +T YK +G Y G W N +DG G ET A+G
Sbjct: 67 GKRHGLGIETKGRWLYKGEWTHGFKGRYGTRQSTSSGAKYEGTWNNGLQDGYGTETYADG 126
Query: 114 DVFNGCWSNDFVYGYGV 130
+ G ++N +GYGV
Sbjct: 127 GTYQGQFTNGMRHGYGV 143
Score = 65.9 bits (159), Expect = 2e-10
Identities = 49/176 (27%), Positives = 71/176 (39%), Gaps = 38/176 (21%)
Query: 83 GTQTYKNGGSYVGNWKNDKKDGRGIETLANGD-VFNGCWSNDFVYGYGVFRFANGDVYTG 141
G + +GG+Y G W+ K G G+ T G ++G W+ F F VYT
Sbjct: 4 GRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWN---------FGFEVAGVYT- 53
Query: 142 NWTCSDVFDGCRSIALIHGFGVYRYANVGVYIGIWKKHERDGLGI-MSWDTGDVFYGCWS 200
W + F+G S HG G+ +Y G W + G S +G + G W+
Sbjct: 54 -WPSGNTFEGYWSQGKRHGLGIETKGR-WLYKGEWTHGFKGRYGTRQSTSSGAKYEGTWN 111
Query: 201 NGLAHGYGVYRSANGDVSIGNWKTWKMDDGRAIFDWANGDVFDGCMSNGLRHGFGV 256
NGL GYG +A+G + G +NG+RHG+GV
Sbjct: 112 NGLQDGYGTET------------------------YADGGTYQGQFTNGMRHGYGV 143
Score = 45.1 bits (105), Expect = 4e-04
Identities = 20/58 (34%), Positives = 30/58 (51%)
Query: 263 DVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGVYRYANGDVDIGNFRSKLL 320
+ Y+G WK DK G G+ G ++G W + L HGYG +G + G +R +L
Sbjct: 288 ETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHNVL 345
Score = 44.3 bits (103), Expect = 6e-04
Identities = 19/54 (35%), Positives = 33/54 (60%)
Query: 47 YVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGNGTQTYKNGGSYVGNWKND 100
Y+G+W + ++G G+ + SG +YEGE+ N RHG G T +G G ++++
Sbjct: 290 YMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHN 343
Score = 42.0 bits (97), Expect = 0.003
Identities = 17/52 (32%), Positives = 29/52 (55%)
Query: 92 SYVGNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNW 143
+Y+G WKNDK+ G G+ ++G + G W ++ +GYG +G G +
Sbjct: 289 TYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKY 340
Score = 38.9 bits (89), Expect = 0.027
Identities = 17/52 (32%), Positives = 26/52 (49%)
Query: 172 YIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYRSANGDVSIGNWK 223
Y+G WK +R G G+ +G + G W + L HGYG +G G ++
Sbjct: 290 YMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYR 341
Score = 37.0 bits (84), Expect = 0.10
Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 34 HGKRKYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGNGTQ 85
+G R+ T S G+ Y G W +G + G G G Y+G+F RHG G +
Sbjct: 94 YGTRQST-SSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVR 144
Score = 33.1 bits (74), Expect = 1.5
Identities = 15/46 (32%), Positives = 24/46 (51%)
Query: 68 DKYEGEFFGNRRHGNGTQTYKNGGSYVGNWKNDKKDGRGIETLANG 113
+ Y GE+ ++R G G +G Y G W ++ + G G TL +G
Sbjct: 288 ETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDG 333
Score = 32.0 bits (71), Expect = 3.2
Identities = 20/79 (25%), Positives = 32/79 (40%), Gaps = 5/79 (6%)
Query: 285 GDVFDGCWSNGLIHGYGVYRYANGDVDIGNFRSKLLHDNGKYTHSNGTIYEGDWVDKK-- 342
G + G W G HG+G+ G + + G YT +G +EG W K
Sbjct: 11 GGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEGYWSQGKRH 70
Query: 343 ---VTEKGLKIWTLQNSHG 358
+ KG ++ + +HG
Sbjct: 71 GLGIETKGRWLYKGEWTHG 89
Score = 31.2 bits (69), Expect = 5.5
Identities = 17/54 (31%), Positives = 25/54 (45%)
Query: 24 YIGNIKDGLAHGKRKYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGN 77
Y+G K+ G S G Y G+W+D + G G P G + EG++ N
Sbjct: 290 YMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHN 343
>JPH4_MOUSE (Q80WT0) Junctophilin 4 (Junctophilin-like 1 protein)
Length = 628
Score = 70.5 bits (171), Expect = 8e-12
Identities = 51/178 (28%), Positives = 73/178 (40%), Gaps = 40/178 (22%)
Query: 38 KYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGN---GTQTYKNGGSYV 94
K+ + DG YVG W G G G+ P +GE+ G HG G T G SY
Sbjct: 6 KFDFDDGGCYVGGWEAGRAHGYGVCTGPGA---QGEYSGCWAHGFESLGVFTGPGGHSYQ 62
Query: 95 GNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNWTCSDVFDGCRS 154
G+W+ K++G G+E + W+ Y G W G +
Sbjct: 63 GHWQQGKREGLGVERKSR-------WT-----------------YRGEW-----LGGLKG 93
Query: 155 IALIHGFGVYRYANVGVYIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYRS 212
+ GV+ + Y G+WK +DG G ++ G + G W G HGYGV +S
Sbjct: 94 RS-----GVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTYQGQWQAGKRHGYGVRQS 146
Score = 64.3 bits (155), Expect = 6e-10
Identities = 49/175 (28%), Positives = 63/175 (36%), Gaps = 37/175 (21%)
Query: 129 GVFRFANGDVYTGNWTCSDVFDGCRSIALIHGFGVYRYANV-GVYIGIWKKHERDGLGIM 187
G F F +G Y G W HG+GV G Y G W H + LG+
Sbjct: 5 GKFDFDDGGCYVGGWEAGRA----------HGYGVCTGPGAQGEYSGCWA-HGFESLGVF 53
Query: 188 SWDTGDVFYGCWSNGLAHGYGVYRSANGDVSIGNWKTWKMDDGRAIFDWANGDVFDGCMS 247
+ G + G W G G GV R + W + G
Sbjct: 54 TGPGGHSYQGHWQQGKREGLGVERKSR---------------------WT----YRGEWL 88
Query: 248 NGLRHGFGVYRFANGDVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGV 302
GL+ GV+ +G Y G WK DG G ++ G + G W G HGYGV
Sbjct: 89 GGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTYQGQWQAGKRHGYGV 143
Score = 60.8 bits (146), Expect = 7e-09
Identities = 44/142 (30%), Positives = 59/142 (40%), Gaps = 6/142 (4%)
Query: 185 GIMSWDTGDVFYGCWSNGLAHGYGVYRS--ANGDVSIGNWKTWKMDDGRAIFDWANGDVF 242
G +D G + G W G AHGYGV A G+ S G W G +F G +
Sbjct: 5 GKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYS-GCWAHGFESLG--VFTGPGGHSY 61
Query: 243 DGCMSNGLRHGFGVYRFANGDVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGV 302
G G R G GV R + Y G W +G+ V G + G W +G GYG
Sbjct: 62 QGHWQQGKREGLGVERKSRW-TYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGT 120
Query: 303 YRYANGDVDIGNFRSKLLHDNG 324
Y++G G +++ H G
Sbjct: 121 ETYSDGGTYQGQWQAGKRHGYG 142
Score = 60.1 bits (144), Expect = 1e-08
Identities = 41/136 (30%), Positives = 59/136 (43%), Gaps = 24/136 (17%)
Query: 18 YSDEGVYIGNIKDGLAHGKRKYTWSDGS-IYVGDWVDGDKTGKGLFIQPSGDKYEGEFFG 76
+ D G Y+G + G AHG T Y G W G ++ G+F P G Y+G +
Sbjct: 9 FDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFES-LGVFTGPGGHSYQGHWQQ 67
Query: 77 NRRHGNGTQ-----TYK-----------------NGGSYVGNWKNDKKDGRGIETLANGD 114
+R G G + TY+ +G Y G WK+ +DG G ET ++G
Sbjct: 68 GKREGLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGG 127
Query: 115 VFNGCWSNDFVYGYGV 130
+ G W +GYGV
Sbjct: 128 TYQGQWQAGKRHGYGV 143
Score = 49.7 bits (117), Expect = 2e-05
Identities = 21/56 (37%), Positives = 34/56 (60%)
Query: 46 IYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGNGTQTYKNGGSYVGNWKNDK 101
+Y G+W ++G G+ + +G +YEGE+ GNRRHG G T +G G +K ++
Sbjct: 281 VYAGEWRADRRSGYGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNR 336
Score = 39.3 bits (90), Expect = 0.020
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Query: 263 DVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGVYRYANGDVDIGNF-RSKLLH 321
+VY G W+ D+ G G+ G ++G W HGYG +G + G + R++L+H
Sbjct: 280 EVYAGEWRADRRSGYGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVH 339
Score = 36.6 bits (83), Expect = 0.13
Identities = 18/66 (27%), Positives = 32/66 (48%)
Query: 93 YVGNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNWTCSDVFDGC 152
Y G W+ D++ G G+ +NG + G W + +GYG +G G + + + G
Sbjct: 282 YAGEWRADRRSGYGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGG 341
Query: 153 RSIALI 158
R +L+
Sbjct: 342 RVRSLL 347
Score = 35.8 bits (81), Expect = 0.22
Identities = 20/59 (33%), Positives = 28/59 (46%), Gaps = 1/59 (1%)
Query: 70 YEGEFFGNRRHGNGTQTYKNGGSYVGNWKNDKKDGRGIETLANGDVFNGCWS-NDFVYG 127
Y GE+ +RR G G NG Y G W +++ G G T +G G + N V+G
Sbjct: 282 YAGEWRADRRSGYGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHG 340
Score = 35.8 bits (81), Expect = 0.22
Identities = 18/60 (30%), Positives = 25/60 (41%)
Query: 171 VYIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYRSANGDVSIGNWKTWKMDDG 230
VY G W+ R G G+ G + G W HGYG +G G +K ++ G
Sbjct: 281 VYAGEWRADRRSGYGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHG 340
Score = 35.0 bits (79), Expect = 0.38
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 8/66 (12%)
Query: 22 GVYIGNIKDGLAHGKRKYTWSD--GSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRR 79
G ++G +K R W G Y G W DG + G G G Y+G++ +R
Sbjct: 85 GEWLGGLKG------RSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTYQGQWQAGKR 138
Query: 80 HGNGTQ 85
HG G +
Sbjct: 139 HGYGVR 144
Score = 31.6 bits (70), Expect = 4.2
Identities = 17/56 (30%), Positives = 26/56 (46%)
Query: 23 VYIGNIKDGLAHGKRKYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNR 78
VY G + G S+G Y G+W+ + G G +P G + EG++ NR
Sbjct: 281 VYAGEWRADRRSGYGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNR 336
Score = 30.4 bits (67), Expect = 9.5
Identities = 20/69 (28%), Positives = 34/69 (48%), Gaps = 1/69 (1%)
Query: 232 AIFDWANGDVFDGCMSNGLRHGFGVYRFANGDVYIGNWKKDKMDGTGIMSWVVGDVFDGC 291
A+ + + +V+ G R G+GV + +NG Y G W ++ G G + G +G
Sbjct: 272 ALIEGSATEVYAGEWRADRRSGYGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGK 331
Query: 292 WS-NGLIHG 299
+ N L+HG
Sbjct: 332 YKRNRLVHG 340
>JPH4_HUMAN (Q96JJ6) Junctophilin 4 (Junctophilin-like 1 protein)
Length = 628
Score = 70.5 bits (171), Expect = 8e-12
Identities = 51/178 (28%), Positives = 73/178 (40%), Gaps = 40/178 (22%)
Query: 38 KYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGN---GTQTYKNGGSYV 94
K+ + DG YVG W G G G+ P +GE+ G HG G T G SY
Sbjct: 6 KFDFDDGGCYVGGWEAGRAHGYGVCTGPGA---QGEYSGCWAHGFESLGVFTGPGGHSYQ 62
Query: 95 GNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNWTCSDVFDGCRS 154
G+W+ K++G G+E + W+ Y G W G +
Sbjct: 63 GHWQQGKREGLGVERKSR-------WT-----------------YRGEW-----LGGLKG 93
Query: 155 IALIHGFGVYRYANVGVYIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYRS 212
+ GV+ + Y G+WK +DG G ++ G + G W G HGYGV +S
Sbjct: 94 RS-----GVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTYQGQWQAGKRHGYGVRQS 146
Score = 64.3 bits (155), Expect = 6e-10
Identities = 49/175 (28%), Positives = 63/175 (36%), Gaps = 37/175 (21%)
Query: 129 GVFRFANGDVYTGNWTCSDVFDGCRSIALIHGFGVYRYANV-GVYIGIWKKHERDGLGIM 187
G F F +G Y G W HG+GV G Y G W H + LG+
Sbjct: 5 GKFDFDDGGCYVGGWEAGRA----------HGYGVCTGPGAQGEYSGCWA-HGFESLGVF 53
Query: 188 SWDTGDVFYGCWSNGLAHGYGVYRSANGDVSIGNWKTWKMDDGRAIFDWANGDVFDGCMS 247
+ G + G W G G GV R + W + G
Sbjct: 54 TGPGGHSYQGHWQQGKREGLGVERKSR---------------------WT----YRGEWL 88
Query: 248 NGLRHGFGVYRFANGDVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGV 302
GL+ GV+ +G Y G WK DG G ++ G + G W G HGYGV
Sbjct: 89 GGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTYQGQWQAGKRHGYGV 143
Score = 60.8 bits (146), Expect = 7e-09
Identities = 44/142 (30%), Positives = 59/142 (40%), Gaps = 6/142 (4%)
Query: 185 GIMSWDTGDVFYGCWSNGLAHGYGVYRS--ANGDVSIGNWKTWKMDDGRAIFDWANGDVF 242
G +D G + G W G AHGYGV A G+ S G W G +F G +
Sbjct: 5 GKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYS-GCWAHGFESLG--VFTGPGGHSY 61
Query: 243 DGCMSNGLRHGFGVYRFANGDVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGV 302
G G R G GV R + Y G W +G+ V G + G W +G GYG
Sbjct: 62 QGHWQQGKREGLGVERKSRW-TYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGT 120
Query: 303 YRYANGDVDIGNFRSKLLHDNG 324
Y++G G +++ H G
Sbjct: 121 ETYSDGGTYQGQWQAGKRHGYG 142
Score = 60.1 bits (144), Expect = 1e-08
Identities = 41/136 (30%), Positives = 59/136 (43%), Gaps = 24/136 (17%)
Query: 18 YSDEGVYIGNIKDGLAHGKRKYTWSDGS-IYVGDWVDGDKTGKGLFIQPSGDKYEGEFFG 76
+ D G Y+G + G AHG T Y G W G ++ G+F P G Y+G +
Sbjct: 9 FDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFES-LGVFTGPGGHSYQGHWQQ 67
Query: 77 NRRHGNGTQ-----TYK-----------------NGGSYVGNWKNDKKDGRGIETLANGD 114
+R G G + TY+ +G Y G WK+ +DG G ET ++G
Sbjct: 68 GKREGLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGG 127
Query: 115 VFNGCWSNDFVYGYGV 130
+ G W +GYGV
Sbjct: 128 TYQGQWQAGKRHGYGV 143
Score = 49.3 bits (116), Expect = 2e-05
Identities = 21/56 (37%), Positives = 34/56 (60%)
Query: 46 IYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGNGTQTYKNGGSYVGNWKNDK 101
+Y G+W ++G G+ + +G +YEGE+ GNRRHG G T +G G +K ++
Sbjct: 281 VYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNR 336
Score = 39.3 bits (90), Expect = 0.020
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Query: 263 DVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGVYRYANGDVDIGNF-RSKLLH 321
+VY G W+ D+ G G+ G ++G W HGYG +G + G + R++L+H
Sbjct: 280 EVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVH 339
Score = 36.2 bits (82), Expect = 0.17
Identities = 18/60 (30%), Positives = 25/60 (41%)
Query: 171 VYIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYRSANGDVSIGNWKTWKMDDG 230
VY G W+ R G G+ G + G W HGYG +G G +K ++ G
Sbjct: 281 VYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHG 340
Score = 36.2 bits (82), Expect = 0.17
Identities = 18/66 (27%), Positives = 32/66 (48%)
Query: 93 YVGNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNWTCSDVFDGC 152
Y G W+ D++ G G+ +NG + G W + +GYG +G G + + + G
Sbjct: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGG 341
Query: 153 RSIALI 158
R +L+
Sbjct: 342 RVRSLL 347
Score = 35.4 bits (80), Expect = 0.29
Identities = 20/59 (33%), Positives = 28/59 (46%), Gaps = 1/59 (1%)
Query: 70 YEGEFFGNRRHGNGTQTYKNGGSYVGNWKNDKKDGRGIETLANGDVFNGCWS-NDFVYG 127
Y GE+ +RR G G NG Y G W +++ G G T +G G + N V+G
Sbjct: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHG 340
Score = 35.0 bits (79), Expect = 0.38
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 8/66 (12%)
Query: 22 GVYIGNIKDGLAHGKRKYTWSD--GSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRR 79
G ++G +K R W G Y G W DG + G G G Y+G++ +R
Sbjct: 85 GEWLGGLKG------RSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGTYQGQWQAGKR 138
Query: 80 HGNGTQ 85
HG G +
Sbjct: 139 HGYGVR 144
Score = 31.6 bits (70), Expect = 4.2
Identities = 21/69 (30%), Positives = 34/69 (48%), Gaps = 1/69 (1%)
Query: 232 AIFDWANGDVFDGCMSNGLRHGFGVYRFANGDVYIGNWKKDKMDGTGIMSWVVGDVFDGC 291
A+ + + +V+ G R GFGV + +NG Y G W ++ G G + G +G
Sbjct: 272 ALIEGSATEVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGK 331
Query: 292 WS-NGLIHG 299
+ N L+HG
Sbjct: 332 YKRNRLVHG 340
Score = 31.2 bits (69), Expect = 5.5
Identities = 17/56 (30%), Positives = 26/56 (46%)
Query: 23 VYIGNIKDGLAHGKRKYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNR 78
VY G + G S+G Y G+W+ + G G +P G + EG++ NR
Sbjct: 281 VYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNR 336
>AKY1_HUMAN (Q9P2S6) Ankyrin repeat and MYND domain protein 1
(Testis specific ankyrin-like protein 1) (Zinc-finger
MYND domain protein 13)
Length = 941
Score = 60.1 bits (144), Expect = 1e-08
Identities = 36/128 (28%), Positives = 59/128 (45%), Gaps = 3/128 (2%)
Query: 46 IYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGNGTQTYKNGGSYVGNWKNDKKDGR 105
+Y G++ K G G F P+G+ Y G+F+ + HG GT + +G S+ G + ++G
Sbjct: 1 MYQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGY 60
Query: 106 GIETLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNWTCSDVFDGCRSIALIHGFGVYR 165
G + +F G + D +G GV + +G G W + C I GF + R
Sbjct: 61 GTMYMKT-RLFQGLYKADQRFGPGVETYPDGSQDVGLWFREQLIKLCTQIP--SGFSLLR 117
Query: 166 YANVGVYI 173
Y +I
Sbjct: 118 YPEFSSFI 125
Score = 52.4 bits (124), Expect = 2e-06
Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 1/98 (1%)
Query: 23 VYIGNIKDGLAHGKRKYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGN 82
+Y G + G K++W G Y G + G G ++ P G + G F+ + R G
Sbjct: 1 MYQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGY 60
Query: 83 GTQTYKNGGSYVGNWKNDKKDGRGIETLANGDVFNGCW 120
GT Y + G +K D++ G G+ET +G G W
Sbjct: 61 GTM-YMKTRLFQGLYKADQRFGPGVETYPDGSQDVGLW 97
Score = 42.4 bits (98), Expect = 0.002
Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Query: 230 GRAIFDWANGDVFDGCMSNGLRHGFGVYRFANGDVYIGNWKKDKMDGTGIMSWVVGDVFD 289
G F W G+ + G HG G Y + +G + G + +G G M ++ +F
Sbjct: 13 GYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGYGTM-YMKTRLFQ 71
Query: 290 GCWSNGLIHGYGVYRYANGDVDIGN-FRSKLL 320
G + G GV Y +G D+G FR +L+
Sbjct: 72 GLYKADQRFGPGVETYPDGSQDVGLWFREQLI 103
Score = 38.9 bits (89), Expect = 0.027
Identities = 28/108 (25%), Positives = 44/108 (39%), Gaps = 11/108 (10%)
Query: 115 VFNGCWSNDFVYGYGVFRFANGDVYTGNWTCSDVFDGCRSIALIHGFGVYRYANVGVYIG 174
++ G + + GYG F + G+ Y G + D C HG G Y + + + G
Sbjct: 1 MYQGEFGLNMKLGYGKFSWPTGESYHGQF----YRDHC------HGLGTYMWPDGSSFTG 50
Query: 175 IWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYRSANGDVSIGNW 222
+ R+G G M T +F G + G GV +G +G W
Sbjct: 51 TFYLSHREGYGTMYMKT-RLFQGLYKADQRFGPGVETYPDGSQDVGLW 97
Score = 38.1 bits (87), Expect = 0.045
Identities = 28/122 (22%), Positives = 46/122 (36%), Gaps = 25/122 (20%)
Query: 171 VYIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYRSANGDVSIGNWKTWKMDDG 230
+Y G + + + G G SW TG+ ++G + HG G Y
Sbjct: 1 MYQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYM------------------- 41
Query: 231 RAIFDWANGDVFDGCMSNGLRHGFGVYRFANGDVYIGNWKKDKMDGTGIMSWVVGDVFDG 290
W +G F G R G+G + ++ G +K D+ G G+ ++ G G
Sbjct: 42 -----WPDGSSFTGTFYLSHREGYGT-MYMKTRLFQGLYKADQRFGPGVETYPDGSQDVG 95
Query: 291 CW 292
W
Sbjct: 96 LW 97
Score = 35.8 bits (81), Expect = 0.22
Identities = 23/98 (23%), Positives = 41/98 (41%), Gaps = 1/98 (1%)
Query: 241 VFDGCMSNGLRHGFGVYRFANGDVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGY 300
++ G ++ G+G + + G+ Y G + +D G G W G F G + GY
Sbjct: 1 MYQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGY 60
Query: 301 GVYRYANGDVDIGNFRSKLLHDNGKYTHSNGTIYEGDW 338
G Y + G +++ G T+ +G+ G W
Sbjct: 61 GT-MYMKTRLFQGLYKADQRFGPGVETYPDGSQDVGLW 97
>SET7_MOUSE (Q8VHL1) Histone-lysine N-methyltransferase, H3 lysine-4
specific (EC 2.1.1.43) (Histone H3-K4 methyltransferase)
(H3-K4-HMTase) (SET domain-containing protein 7)
Length = 366
Score = 54.3 bits (129), Expect = 6e-07
Identities = 32/113 (28%), Positives = 55/113 (48%), Gaps = 1/113 (0%)
Query: 30 DGLAHGKRKYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGNGTQTYKN 89
DGL HG T+S + G++V G+K G+G F G EG + + G G TY++
Sbjct: 19 DGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYED 78
Query: 90 GGSYVGNWKNDKKDGRGIETLANGD-VFNGCWSNDFVYGYGVFRFANGDVYTG 141
GG G + + + +G E ++G +F G + ++ +G + +G G
Sbjct: 79 GGVLQGTYVDGELNGPAQEYDSDGRLIFKGQYKDNNRHGVCWIHYPDGGSLVG 131
Score = 46.2 bits (108), Expect = 2e-04
Identities = 39/171 (22%), Positives = 76/171 (43%), Gaps = 13/171 (7%)
Query: 248 NGLRHGFGVYRFANGDVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGVYRYAN 307
+GL HGF +++ D + GN+ + +G G + G +G + + + G GVY Y +
Sbjct: 19 DGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYED 78
Query: 308 GDVDIGNFRSKLLHDNGKYTHSNG-TIYEGDWVDKK--------VTEKGLKIWTLQNSHG 358
G V G + L+ + S+G I++G + D + G + +
Sbjct: 79 GGVLQGTYVDGELNGPAQEYDSDGRLIFKGQYKDNNRHGVCWIHYPDGGSLVGEVNEDGE 138
Query: 359 STSLQISNKGQSEVSSLSPLVIKREYMQG----VLIVEKIRPYSEVTHNNN 405
T +I+ + ++L I E ++G ++ E+ RP+ EVT ++
Sbjct: 139 MTGEKIAYVYPDQRTALYGKFIDGEMIEGKLATLMATEEGRPHFEVTSGSS 189
Score = 45.4 bits (106), Expect = 3e-04
Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 5/81 (6%)
Query: 21 EGVYIGNIKDGLAHGKRKYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDK-YEGEFFGNRR 79
EG Y+ D G+ YT+ DG + G +VDG+ G G ++G++ N R
Sbjct: 60 EGYYV----DDALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDSDGRLIFKGQYKDNNR 115
Query: 80 HGNGTQTYKNGGSYVGNWKND 100
HG Y +GGS VG D
Sbjct: 116 HGVCWIHYPDGGSLVGEVNED 136
Score = 42.0 bits (97), Expect = 0.003
Identities = 20/64 (31%), Positives = 34/64 (52%)
Query: 80 HGNGTQTYKNGGSYVGNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVY 139
HG T TY + + GN+ + +K+GRG +G G + +D + G GV+ + +G V
Sbjct: 23 HGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVL 82
Query: 140 TGNW 143
G +
Sbjct: 83 QGTY 86
Score = 40.4 bits (93), Expect = 0.009
Identities = 27/116 (23%), Positives = 48/116 (41%)
Query: 157 LIHGFGVYRYANVGVYIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYRSANGD 216
L HGF Y++ + G + E++G G + G G + + G GVY +G
Sbjct: 21 LPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGG 80
Query: 217 VSIGNWKTWKMDDGRAIFDWANGDVFDGCMSNGLRHGFGVYRFANGDVYIGNWKKD 272
V G + +++ +D +F G + RHG + +G +G +D
Sbjct: 81 VLQGTYVDGELNGPAQEYDSDGRLIFKGQYKDNNRHGVCWIHYPDGGSLVGEVNED 136
Score = 40.4 bits (93), Expect = 0.009
Identities = 25/94 (26%), Positives = 44/94 (46%), Gaps = 3/94 (3%)
Query: 13 FKEMLYSDEGVYIGNIKDGLAHGKRKYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEG 72
F + YS + GN G +G+ K+ + DGS G +VD G+G++ G +G
Sbjct: 25 FCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQG 84
Query: 73 EFFGNRRHGNGTQTYKNGGSYV--GNWKNDKKDG 104
+ +G Q Y + G + G +K++ + G
Sbjct: 85 TYVDGELNG-PAQEYDSDGRLIFKGQYKDNNRHG 117
Score = 36.6 bits (83), Expect = 0.13
Identities = 17/64 (26%), Positives = 35/64 (54%)
Query: 236 WANGDVFDGCMSNGLRHGFGVYRFANGDVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNG 295
+++ D F+G +G ++G G + F +G G + D + G G+ ++ G V G + +G
Sbjct: 30 YSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQGTYVDG 89
Query: 296 LIHG 299
++G
Sbjct: 90 ELNG 93
Score = 33.9 bits (76), Expect = 0.85
Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 2/114 (1%)
Query: 201 NGLAHGYGVYRSANGDVSIGNWKTWKMDDGRAIFDWANGDVFDGCMSNGLRHGFGVYRFA 260
+GL HG+ ++ D GN+ + + GR F + +G +G + G GVY +
Sbjct: 19 DGLPHGFCTVTYSSTDRFEGNFVHGEKN-GRGKFFFFDGSTLEGYYVDDALQGQGVYTYE 77
Query: 261 NGDVYIGNWKKDKMDGTGIMSWVVGD-VFDGCWSNGLIHGYGVYRYANGDVDIG 313
+G V G + +++G G +F G + + HG Y +G +G
Sbjct: 78 DGGVLQGTYVDGELNGPAQEYDSDGRLIFKGQYKDNNRHGVCWIHYPDGGSLVG 131
>SET7_HUMAN (Q8WTS6) Histone-lysine N-methyltransferase, H3 lysine-4
specific (EC 2.1.1.43) (Histone H3-K4 methyltransferase)
(H3-K4-HMTase) (SET domain-containing protein 7) (Set9)
(SET7/9)
Length = 366
Score = 54.3 bits (129), Expect = 6e-07
Identities = 32/113 (28%), Positives = 54/113 (47%), Gaps = 1/113 (0%)
Query: 30 DGLAHGKRKYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDKYEGEFFGNRRHGNGTQTYKN 89
DGL HG T+S + G++V G+K G+G F G EG + + G G TY++
Sbjct: 19 DGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYED 78
Query: 90 GGSYVGNWKNDKKDGRGIETLANGD-VFNGCWSNDFVYGYGVFRFANGDVYTG 141
GG G + + + +G E +G +F G + ++ +G + +G G
Sbjct: 79 GGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVG 131
Score = 43.9 bits (102), Expect = 8e-04
Identities = 40/174 (22%), Positives = 77/174 (43%), Gaps = 19/174 (10%)
Query: 248 NGLRHGFGVYRFANGDVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNGLIHGYGVYRYAN 307
+GL HGF +++ D + GN+ + +G G + G +G + + + G GVY Y +
Sbjct: 19 DGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYED 78
Query: 308 GDVDIGNFRSKLLHDNGKYTHSNG-TIYEGDWVDKKVTEKGLKIWTLQNSHGSTSLQISN 366
G V G + L+ + ++G I++G + D G+ W GS +++
Sbjct: 79 GGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDN--IRHGV-CWIYYPDGGSLVGEVNE 135
Query: 367 KGQ-----------SEVSSLSPLVIKREYMQG----VLIVEKIRPYSEVTHNNN 405
G+ E ++L I E ++G ++ E+ RP+ E+ N+
Sbjct: 136 DGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRPHFELMPGNS 189
Score = 42.0 bits (97), Expect = 0.003
Identities = 20/64 (31%), Positives = 34/64 (52%)
Query: 80 HGNGTQTYKNGGSYVGNWKNDKKDGRGIETLANGDVFNGCWSNDFVYGYGVFRFANGDVY 139
HG T TY + + GN+ + +K+GRG +G G + +D + G GV+ + +G V
Sbjct: 23 HGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVL 82
Query: 140 TGNW 143
G +
Sbjct: 83 QGTY 86
Score = 42.0 bits (97), Expect = 0.003
Identities = 27/116 (23%), Positives = 49/116 (41%)
Query: 157 LIHGFGVYRYANVGVYIGIWKKHERDGLGIMSWDTGDVFYGCWSNGLAHGYGVYRSANGD 216
L HGF Y++ + G + E++G G + G G + + G GVY +G
Sbjct: 21 LPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGG 80
Query: 217 VSIGNWKTWKMDDGRAIFDWANGDVFDGCMSNGLRHGFGVYRFANGDVYIGNWKKD 272
V G + +++ +D +F G + +RHG + +G +G +D
Sbjct: 81 VLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVGEVNED 136
Score = 39.7 bits (91), Expect = 0.016
Identities = 41/179 (22%), Positives = 68/179 (37%), Gaps = 35/179 (19%)
Query: 13 FKEMLYSDEGVYIGNIKDGLAHGKRKYTWSDGSIYVGDWVDGDKTGKGLFIQPSGDK--- 69
F + YS + GN G +G+ K+ + DGS G +VD G+G++ G
Sbjct: 25 FCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQG 84
Query: 70 ---------------------YEGEFFGNRRHGNGTQTYKNGGSYVGNWKNDKKDGRGIE 108
++G++ N RHG Y +GGS VG D +
Sbjct: 85 TYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVGEVNEDGE------ 138
Query: 109 TLANGDVFNGCWSNDFVYGYGVFRFANGDVYTGNW-TCSDVFDGCRSIALIHGFGVYRY 166
G+ + ++ YG +F +G++ G T +G L+ G VY +
Sbjct: 139 --MTGEKIAYVYPDERTALYG--KFIDGEMIEGKLATLMSTEEGRPHFELMPGNSVYHF 193
Score = 36.6 bits (83), Expect = 0.13
Identities = 17/64 (26%), Positives = 35/64 (54%)
Query: 236 WANGDVFDGCMSNGLRHGFGVYRFANGDVYIGNWKKDKMDGTGIMSWVVGDVFDGCWSNG 295
+++ D F+G +G ++G G + F +G G + D + G G+ ++ G V G + +G
Sbjct: 30 YSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQGTYVDG 89
Query: 296 LIHG 299
++G
Sbjct: 90 ELNG 93
Score = 35.8 bits (81), Expect = 0.22
Identities = 28/114 (24%), Positives = 51/114 (44%), Gaps = 2/114 (1%)
Query: 201 NGLAHGYGVYRSANGDVSIGNWKTWKMDDGRAIFDWANGDVFDGCMSNGLRHGFGVYRFA 260
+GL HG+ ++ D GN+ + + GR F + +G +G + G GVY +
Sbjct: 19 DGLPHGFCTVTYSSTDRFEGNFVHGEKN-GRGKFFFFDGSTLEGYYVDDALQGQGVYTYE 77
Query: 261 NGDVYIGNWKKDKMDGTGIMSWVVGD-VFDGCWSNGLIHGYGVYRYANGDVDIG 313
+G V G + +++G G +F G + + + HG Y +G +G
Sbjct: 78 DGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPDGGSLVG 131
>ARP_PLAFA (P04931) Asparagine-rich protein (AG319) (ARP) (Fragment)
Length = 537
Score = 35.8 bits (81), Expect = 0.22
Identities = 25/102 (24%), Positives = 44/102 (42%), Gaps = 4/102 (3%)
Query: 320 LHDNGKYTHSNGTIYEGDWVDKKVTEKGLKIWTLQNSHGSTSL--QISNKGQSEVSSLSP 377
+H KY ++N ++ D +K T +K T+ N + + I+N + + S+ +
Sbjct: 110 IHFKNKYDNNNSSMKNTD-NNKTDTSYNMK-GTINNDNNNMDYLRNINNINEYKGSAKNK 167
Query: 378 LVIKREYMQGVLIVEKIRPYSEVTHNNNNNNNNNNKKQGAFS 419
+ + + +NNNNNNNNN G FS
Sbjct: 168 FYTNYMNKNNLKFTQNNNDNMNINEDNNNNNNNNNNNNGVFS 209
>MUR2_ENTHR (P39046) Muramidase-2 precursor (EC 3.2.1.17)
(1,4-beta-N-acetylmuramoylhydrolase) (Peptidoglycan
hydrolase) (Pg-hydrolase-2) (Lysosyme)
Length = 666
Score = 35.0 bits (79), Expect = 0.38
Identities = 43/190 (22%), Positives = 64/190 (33%), Gaps = 19/190 (10%)
Query: 259 FANGDVYIGNWKKDKMDGTGIMSWVVG----DVFDGCWSNGLIHGYGVYRY-------AN 307
F NG Y G WK + T + + G D N +I YG+ +Y A
Sbjct: 163 FGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIITTYGLTKYDTPASGNAG 222
Query: 308 GDVDIGNFRSKLLHDNGKYTHSNGTIYEGDWVDKKVTEKGLKIWTLQNSHGSTSLQISNK 367
G V IGN + N T N + G +W + +S G T Q+
Sbjct: 223 GGVTIGNGGNTGNTSNSGSTSGNSGGSATTTGTTYTVKSGDSVWGISHSFGITMAQLIEW 282
Query: 368 GQSEVSSLSP---LVIKREYMQGVLIVEKIRPYSEVTHNNNNNNNNNNKKQGAFSAKK-- 422
+ + + P L IK G + + N + N N + G + K
Sbjct: 283 NNIKNNFIYPGQKLTIKGGQSAG---SSTTNTGNNASSGNTSGNTNTSGSTGQATGAKYT 339
Query: 423 AKKSSCIWAI 432
K +W I
Sbjct: 340 VKSGDSVWKI 349
>HKLB_LYCES (O22300) Homeobox protein knotted-1 like LET12
Length = 426
Score = 35.0 bits (79), Expect = 0.38
Identities = 13/26 (50%), Positives = 20/26 (76%)
Query: 399 EVTHNNNNNNNNNNKKQGAFSAKKAK 424
E +NNNNNNNNNN+++ ++ +K K
Sbjct: 139 ENNNNNNNNNNNNNEEENSWEREKCK 164
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.319 0.140 0.457
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,711,330
Number of Sequences: 164201
Number of extensions: 3225105
Number of successful extensions: 11135
Number of sequences better than 10.0: 86
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 9196
Number of HSP's gapped (non-prelim): 912
length of query: 440
length of database: 59,974,054
effective HSP length: 113
effective length of query: 327
effective length of database: 41,419,341
effective search space: 13544124507
effective search space used: 13544124507
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Medicago: description of AC148755.12