BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC148607.16 - phase: 0 /pseudo
         (619 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

BFR1_SCHPO (P41820) Brefeldin A resistance protein                    266  9e-71
PDR5_YEAST (P33302) Suppressor of toxicity of sporidesmin             266  2e-70
CGR1_CANGA (O74208) ATP-binding cassette transporter CGR1 (Pleom...   264  6e-70
PDRA_YEAST (P51533) ATP-dependent permease PDR10                      263  8e-70
PDRF_YEAST (Q04182) ATP-dependent permease PDR15                      263  1e-69
SNQ2_YEAST (P32568) SNQ2 protein                                      248  3e-65
CDR3_CANAL (O42690) Opaque-specific ABC transporter CDR3              248  3e-65
CDR2_CANAL (P78595) Multidrug resistance protein CDR2                 243  1e-63
CDR1_CANAL (P43071) Multidrug resistance protein CDR1                 239  2e-62
PDRC_YEAST (Q02785) ATP-dependent permease PDR12                      238  5e-62
YN99_YEAST (P53756) Probable ATP-dependent transporter YNR070W        237  6e-62
CDR4_CANAL (O74676) ABC transporter CDR4                              236  1e-61
ABG4_HUMAN (Q9H172) ATP-binding cassette, sub-family G, member 4      214  5e-55
WHIT_DROME (P10090) White protein                                     208  3e-53
ABG1_MOUSE (Q64343) ATP-binding cassette, sub-family G, member 1...   205  3e-52
WHIT_CERCA (Q17320) White protein                                     202  3e-51
ABG1_HUMAN (P45844) ATP-binding cassette, sub-family G, member 1...   199  2e-50
WHIT_LUCCU (Q05360) White protein                                     197  7e-50
WHIT_ANOGA (Q27256) White protein                                     194  8e-49
YQ5C_CAEEL (Q09466) Putative ABC transporter C16C10.12 in chromo...   179  2e-44

>BFR1_SCHPO (P41820) Brefeldin A resistance protein
          Length = 1530

 Score =  266 bits (681), Expect = 9e-71
 Identities = 170/533 (31%), Positives = 282/533 (52%), Gaps = 32/533 (6%)

Query: 37   LLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKTGGYIGGNITISGYPKKQETFARI 96
            LL G+ G   PG LTALMG +GAGKTTL++VL+ R   G + G++ ++G      TF R 
Sbjct: 900  LLNGVQGFVVPGKLTALMGESGAGKTTLLNVLAQRVDTGVVTGDMLVNGRGL-DSTFQRR 958

Query: 97   SGYCEQTDIHSPHVTVYESLLYSAWLRLSPDINAETRKMFIEEVMELVELKPLRYALVGL 156
            +GY +Q D+H    TV E+L +SA LR    +    +  ++E V++L+E++    A++G 
Sbjct: 959  TGYVQQQDVHIGESTVREALRFSAALRQPASVPLSEKYEYVESVIKLLEMESYAEAIIGT 1018

Query: 157  PGVSGLSTEQRKRLTVAVELVANPSII-FMDEPTSGLDARAAAIVMRAVRNTVDTGRTVV 215
            PG SGL+ EQRKR T+ VEL A P+++ F+DEPTSGLD+++A  ++  +R   D G+ ++
Sbjct: 1019 PG-SGLNVEQRKRATIGVELAAKPALLLFLDEPTSGLDSQSAWSIVCFLRKLADAGQAIL 1077

Query: 216  CTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNSSNLINYFEGVQGVSKIKDGYNPAT 275
            CTIHQPS  +F+ FD LLLL++GG+ +Y G +G +S  L+NYFE   G     D  NPA 
Sbjct: 1078 CTIHQPSAVLFDQFDRLLLLQKGGKTVYFGDIGEHSKTLLNYFES-HGAVHCPDDGNPAE 1136

Query: 276  WMLEVTTSSKEVELRIDYAEVYKNSELYRRNKALIKELSAPAPCSKDLYFPSRYSRSFFT 335
            ++L+V  +        D+ EV+ NSE  +   A + +++A    S+D    S+  RS + 
Sbjct: 1137 YILDVIGAGATATTNRDWHEVWNNSEERKAISAELDKINASFSNSEDKKTLSKEDRSTYA 1196

Query: 336  -----QCIACLWKQHWSYWRNPEYNAIRFLYSTAVAVLLGSMFWNLGSKIEKDQDLFNAM 390
                 Q    + +   SYWR P     +        + +G  F+N G  +   Q++ N +
Sbjct: 1197 MPLWFQVKMVMTRNFQSYWREPSILMSKLALDIFAGLFIGFTFYNQGLGV---QNIQNKL 1253

Query: 391  GSMYAAVILIGAMNSNSVQPVVGVERTVF-YRERAARMYSAFPYALAQVVIQLPY----- 444
             +++ A +L   +  N +QP     R VF  RE+ + +YS   +  + +++++P+     
Sbjct: 1254 FAVFMATVLAVPL-INGLQPKFIELRNVFEVREKPSNIYSWVAFVFSAIIVEIPFNLVFG 1312

Query: 445  -VFVQAVVYGIVVYVMIGFEWTLVKVVWCLFFMYFTFLYFTFYGMMSVAMTPNNHISIIV 503
             +F     Y I  Y  I          W L +M+F  +YF+ +G    +  PN   + +V
Sbjct: 1313 TLFFLCWFYPIKFYKHIHHPGDKTGYAW-LLYMFFQ-MYFSTFGQAVASACPNAQTASVV 1370

Query: 504  SSAFYSVWNLFSGFVLPRPGK**LISVILSIPVWWRWYSWANPVAWSLYGLVT 556
            +S  ++    F+G + P            ++  +W W     P  + + GL++
Sbjct: 1371 NSLLFTFVITFNGVLQPNS----------NLVGFWHWMHSLTPFTYLIEGLLS 1413



 Score = 94.4 bits (233), Expect = 8e-19
 Identities = 122/592 (20%), Positives = 240/592 (39%), Gaps = 84/592 (14%)

Query: 28  RGVIEDKLV---LLKGLSGAFRPGVLTALMGVTGAGKTT-LMDVLSGRKTGGYIGGNITI 83
           R + E ++V   +L         G L  ++G  G+G +T L  V S       + G    
Sbjct: 164 RAITEKQVVEKAILSHCHALANAGELVMVLGQPGSGCSTFLRSVTSDTVHYKRVEGTTHY 223

Query: 84  SGYPKK--QETFARISGYCEQTDIHSPHVTVYESLLYSAWLRLSPDINAE-TRKMFIEEV 140
            G  K   ++ F     Y  + D+H P +T  E+L ++A  R   +     TR+ ++   
Sbjct: 224 DGIDKADMKKFFPGDLLYSGENDVHFPSLTTAETLDFAAKCRTPNNRPCNLTRQEYVSRE 283

Query: 141 MELVE----LKPLRYALVGLPGVSGLSTEQRKRLTVAVELVANPSIIFMDEPTSGLDARA 196
             L+     L       VG   V G+S  +RKR+T++      P+I   D  T GLD+  
Sbjct: 284 RHLIATAFGLTHTFNTKVGNDFVRGVSGGERKRVTISEGFATRPTIACWDNSTRGLDSST 343

Query: 197 AAIVMRAVRNTVDTGR-TVVCTIHQPSIDIFESFDELLLLKQGGQEIYVGP--------- 246
           A   +  +R   +  + T   T +Q S  I++ FD + +L   G++IY GP         
Sbjct: 344 AFEFVNVLRTCANELKMTSFVTAYQASEKIYKLFDRICVL-YAGRQIYYGPADKAKQYFL 402

Query: 247 -LGHNSSNLINYFEGVQGVSKIKDGYNPATWMLEVTTSSKEVELRIDYAEVYKN------ 299
            +G +        + +  +S  K  +    +   V  +  E E     + VY +      
Sbjct: 403 DMGFDCHPRETTPDFLTAISDPKARFPRKGFENRVPRTPDEFEQMWRNSSVYADLMAEME 462

Query: 300 -----------------------SELYRRNKALIKELSAPAPCSKDLYFPSRYSRSFFTQ 336
                                  S++    K  +   SA A  SK +   S Y+ +F  Q
Sbjct: 463 SYDKRWTETTPASSEAPEKDNFGSDISATTKHELYRQSAVAEKSKRVKDTSPYTVTFSQQ 522

Query: 337 CIACLWKQHWSYWRNPEY---NAIRFLYSTAVAVLLGSMFWNLGSKIEKDQDLFNAMGSM 393
              CL +    Y  +P Y    A  FL+ +   +++GS+F+++        D+F+  G +
Sbjct: 523 LWYCLARSWERYINDPAYIGSMAFAFLFQS---LIIGSIFYDMKLNTV---DVFSRGGVL 576

Query: 394 YAAVILIGAMNSNSVQPVVGVERTVFYRERAARMYSAFPYALAQVVIQLPYVFVQAVVYG 453
           + +++     + + +  +   +R +  + RA+ +Y      ++ +++ LP+ F+   V+ 
Sbjct: 577 FFSILFCALQSLSEIANMFS-QRPIIAKHRASALYHPAADVISSLIVDLPFRFINISVFS 635

Query: 454 IVVYVMIGFEWTLVKVVWCLFFMYFTFLYF------TFYGMMSVAMTPNNHISIIVSSAF 507
           IV+Y +   + T        F+ YF FL+        F+  ++  M PN   +  +    
Sbjct: 636 IVLYFLTNLKRTAGG-----FWTYFLFLFIGATCMSAFFRSLAGIM-PNVESASALGGIG 689

Query: 508 YSVWNLFSGFVLPRPGK**LISVILSIPVWWRWYSWANPVAWSLYGLVTSQY 559
                +++G+ +P           + +  W+RW ++ +P+ +    L+ +++
Sbjct: 690 VLAIAIYTGYAIPN----------IDVGWWFRWIAYLDPLQFGFESLMINEF 731


>PDR5_YEAST (P33302) Suppressor of toxicity of sporidesmin
          Length = 1511

 Score =  266 bits (679), Expect = 2e-70
 Identities = 154/473 (32%), Positives = 258/473 (53%), Gaps = 16/473 (3%)

Query: 37   LLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKTGGYIGGNITISGYPKKQETFARI 96
            +L  + G  +PG LTALMG +GAGKTTL+D L+ R T G I G+I ++G P+  ++F R 
Sbjct: 887  ILNNVDGWVKPGTLTALMGASGAGKTTLLDCLAERVTMGVITGDILVNGIPR-DKSFPRS 945

Query: 97   SGYCEQTDIHSPHVTVYESLLYSAWLRLSPDINAETRKMFIEEVMELVELKPLRYALVGL 156
             GYC+Q D+H    TV ESL +SA+LR   +++ E +  ++EEV++++E++    A+VG+
Sbjct: 946  IGYCQQQDLHLKTATVRESLRFSAYLRQPAEVSIEEKNRYVEEVIKILEMEKYADAVVGV 1005

Query: 157  PGVSGLSTEQRKRLTVAVELVANPSI-IFMDEPTSGLDARAAAIVMRAVRNTVDTGRTVV 215
             G  GL+ EQRKRLT+ VEL A P + +F+DEPTSGLD++ A  + + ++   + G+ ++
Sbjct: 1006 AG-EGLNVEQRKRLTIGVELTAKPKLLVFLDEPTSGLDSQTAWSICQLMKKLANHGQAIL 1064

Query: 216  CTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNSSNLINYFEGVQGVSKIKDGYNPAT 275
            CTIHQPS  + + FD LL +++GG+ +Y G LG     +I+YFE   G  K     NPA 
Sbjct: 1065 CTIHQPSAILMQEFDRLLFMQRGGKTVYFGDLGEGCKTMIDYFES-HGAHKCPADANPAE 1123

Query: 276  WMLEVTTSSKEVELRIDYAEVYKNSELYRRNKALIKELSAPAPCSKDLYFPS---RYSRS 332
            WMLEV  ++       DY EV++NSE YR  ++ +  +    P    +        +S+S
Sbjct: 1124 WMLEVVGAAPGSHANQDYYEVWRNSEEYRAVQSELDWMERELPKKGSITAAEDKHEFSQS 1183

Query: 333  FFTQCIACLWKQHWSYWRNPEYNAIRFLYSTAVAVLLGSMFWNLGSKIEKDQDLFNAMGS 392
               Q      +    YWR+P+Y   +F+ +    + +G  F+  G+ +   Q L N M +
Sbjct: 1184 IIYQTKLVSIRLFQQYWRSPDYLWSKFILTIFNQLFIGFTFFKAGTSL---QGLQNQMLA 1240

Query: 393  MYAAVILIGAMNSNSVQPVVGVERTVFYRERAARMYSAFPYALAQVVIQLPYVFVQAVVY 452
            ++   ++   +    +   V        RER +R +S   +  AQ+ +++P+  +   + 
Sbjct: 1241 VFMFTVIFNPILQQYLPSFVQQRDLYEARERPSRTFSWISFIFAQIFVEVPWNILAGTIA 1300

Query: 453  GIVVYVMIGFEWTLVKVVWCL-----FFMYFTFLYFTFYGMMSVAMTPNNHIS 500
              + Y  IGF ++       L      F  F+  ++ + G M + +   N ++
Sbjct: 1301 YFIYYYPIGF-YSNASAAGQLHERGALFWLFSCAFYVYVGSMGLLVISFNQVA 1352



 Score =  127 bits (319), Expect = 9e-29
 Identities = 134/569 (23%), Positives = 240/569 (41%), Gaps = 66/569 (11%)

Query: 37  LLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKTGGYIGGN--ITISGYPKK--QET 92
           +LK + G   PG L  ++G  G+G TTL+  +S    G  +G +  I+ SGY     ++ 
Sbjct: 175 ILKPMDGCLNPGELLVVLGRPGSGCTTLLKSISSNTHGFDLGADTKISYSGYSGDDIKKH 234

Query: 93  FARISGYCEQTDIHSPHVTVYESLLYSAWLRLSPD----INAETRKMFIEEV-MELVELK 147
           F     Y  + D+H PH+TV+E+L+  A L+   +    ++ E+    + EV M    L 
Sbjct: 235 FRGEVVYNAEADVHLPHLTVFETLVTVARLKTPQNRIKGVDRESYANHLAEVAMATYGLS 294

Query: 148 PLRYALVGLPGVSGLSTEQRKRLTVAVELVANPSIIFMDEPTSGLDARAAAIVMRAVRNT 207
             R   VG   V G+S  +RKR+++A   +        D  T GLD+  A   +RA++  
Sbjct: 295 HTRNTKVGNDIVRGVSGGERKRVSIAEVSICGSKFQCWDNATRGLDSATALEFIRALKTQ 354

Query: 208 VDTGRT-VVCTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNSSNLINYFEGVQGVSK 266
            D   T     I+Q S D ++ F+++ +L  G Q IY GP    +     YFE +  V  
Sbjct: 355 ADISNTSATVAIYQCSQDAYDLFNKVCVLDDGYQ-IYYGP----ADKAKKYFEDMGYVCP 409

Query: 267 IKDGYNPATWMLEVTTSSKEV-----------------ELRIDYAEVYKNSELYRR-NKA 308
            +     A ++  VT+ S+                   E+   + +     EL +  ++ 
Sbjct: 410 SRQ--TTADFLTSVTSPSERTLNKDMLKKGIHIPQTPKEMNDYWVKSPNYKELMKEVDQR 467

Query: 309 LIKELSAPAPCSKDLYF---------PSRYSRSFFTQCIACLWKQHWSYWRNPEYNAIRF 359
           L+ +  A     K+ +           S Y+ S+  Q    L +  W    N  +     
Sbjct: 468 LLNDDEASREAIKEAHIAKQSKRARPSSPYTVSYMMQVKYLLIRNMWRLRNNIGFTLFMI 527

Query: 360 LYSTAVAVLLGSMFWNLGSKIEKDQDLFNAMGSMYAAVILIGAMNSNSVQPVVGVERTVF 419
           L + ++A++LGSMF+ +  K   D   F   GS     IL  A +S      +   R + 
Sbjct: 528 LGNCSMALILGSMFFKIMKK--GDTSTFYFRGSAMFFAILFNAFSSLLEIFSLYEARPIT 585

Query: 420 YRERAARMYSAFPYALAQVVIQLPYVFVQAVVYGIVVYVMIGFEWTLVKVVWCLFFMYFT 479
            + R   +Y     A A V+ ++P   + AV + I+ Y ++ F          +FF Y  
Sbjct: 586 EKHRTYSLYHPSADAFASVLSEIPSKLIIAVCFNIIFYFLVDFRRN-----GGVFFFYLL 640

Query: 480 FLYFTFYGMMSV-----AMTPNNHISIIVSSAFYSVWNLFSGFVLPRPGK**LISVILSI 534
                 + M  +     ++T     +++ +S      ++++GF +P+            I
Sbjct: 641 INIVAVFSMSHLFRCVGSLTKTLSEAMVPASMLLLALSMYTGFAIPKK----------KI 690

Query: 535 PVWWRWYSWANPVAWSLYGLVTSQYGDVK 563
             W +W  + NP+A+    L+ +++  +K
Sbjct: 691 LRWSKWIWYINPLAYLFESLLINEFHGIK 719


>CGR1_CANGA (O74208) ATP-binding cassette transporter CGR1
            (Pleomorphic drug resistance homolog)
          Length = 1542

 Score =  264 bits (674), Expect = 6e-70
 Identities = 170/567 (29%), Positives = 291/567 (50%), Gaps = 46/567 (8%)

Query: 12   FDEVSYSVDMPQEMRNRGVIEDKLVLLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGR 71
            +  + Y V +  E+R          +L  + G  +PG LTALMG +GAGKTTL+D L+ R
Sbjct: 887  WQNLCYDVPIKTEVRR---------ILNNVDGWVKPGTLTALMGASGAGKTTLLDCLAER 937

Query: 72   KTGGYIGGNITISGYPKKQETFARISGYCEQTDIHSPHVTVYESLLYSAWLRLSPDINAE 131
             T G I G++ ++G P+   +F+R  GYC+Q D+H    TV ESL +SA+LR    ++ E
Sbjct: 938  TTMGVITGDVMVNGRPR-DTSFSRSIGYCQQQDLHLKTATVRESLRFSAYLRQPSSVSIE 996

Query: 132  TRKMFIEEVMELVELKPLRYALVGLPGVSGLSTEQRKRLTVAVELVANPSI-IFMDEPTS 190
             +  ++E V++++E++    A+VG+PG  GL+ EQRKRLT+ VEL A P + +F+DEPTS
Sbjct: 997  EKNEYVEAVIKILEMETYADAVVGVPG-EGLNVEQRKRLTIGVELAAKPKLLVFLDEPTS 1055

Query: 191  GLDARAAAIVMRAVRNTVDTGRTVVCTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHN 250
            GLD++ A    + ++   + G+ ++CTIHQPS  + + FD LL L++GGQ +Y G LG  
Sbjct: 1056 GLDSQTAWATCQLMKKLANHGQAILCTIHQPSAMLMQEFDRLLFLQKGGQTVYFGDLGKG 1115

Query: 251  SSNLINYFEGVQGVSKIKDGYNPATWMLEVTTSSKEVELRIDYAEVYKNSELYRRNKALI 310
               +I YFE   G  K     NPA WMLEV  ++       DY EV++NSE +++ K  +
Sbjct: 1116 CKTMIKYFED-HGAHKCPPDANPAEWMLEVVGAAPGSHANQDYHEVWRNSEQFKQVKQEL 1174

Query: 311  KELSAPAPCSKDLYFPSRYSRSFFTQCIACLWKQ--------HWSYWRNPEYNAIRFLYS 362
            +++       K+L      ++ F T     LW Q           YWR P+Y   +++ +
Sbjct: 1175 EQMEKEL-SQKELDNDEDANKEFATS----LWYQFQLVCVRLFQQYWRTPDYLWSKYILT 1229

Query: 363  TAVAVLLGSMFWNLGSKIEKDQDLFNAMGSMYAAVILIGAMNSNSVQPVVGVERTVFYRE 422
                + +G  F+     +   Q L N M S++   ++   +    +   V        RE
Sbjct: 1230 IFNQLFIGFTFFKADHTL---QGLQNQMLSIFMYTVIFNPLLQQYLPTFVQQRDLYEARE 1286

Query: 423  RAARMYSAFPYALAQVVIQLPYVFVQAVVYGIVVYVMIGFEWTLVKVVWC----LFFMYF 478
            R +R +S   + LAQ+V+++P+  V   +   + Y  +GF     +          F  F
Sbjct: 1287 RPSRTFSWKAFILAQIVVEVPWNIVAGTLAYCIYYYSVGFYANASQAHQLHERGALFWLF 1346

Query: 479  TFLYFTFYGMMSVAMTPNNHI---SIIVSSAFYSVWNLFSGFVLPRPGK**LISVILSIP 535
            +  ++ + G + + +   N +   +  + S  +++   F G V+  P          ++P
Sbjct: 1347 SIAFYVYVGSLGLFVISFNEVAETAAHIGSLMFTMALSFCG-VMATPD---------AMP 1396

Query: 536  VWWRWYSWANPVAWSLYGLVTSQYGDV 562
             +W +    +P+ + +  L+++   +V
Sbjct: 1397 RFWIFMYRVSPLTYLIDALLSTGVANV 1423



 Score =  126 bits (317), Expect = 1e-28
 Identities = 137/567 (24%), Positives = 233/567 (40%), Gaps = 58/567 (10%)

Query: 33  DKLVLLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKTGGYIGGNITIS--GYPKKQ 90
           D   +LK + G  +PG L  ++G  G+G TTL+  +S    G  I  +  IS  G    +
Sbjct: 170 DTFRILKPMDGLLKPGELLVVLGRPGSGCTTLLKSISSTTHGFQISKDSVISYNGLTPNE 229

Query: 91  --ETFARISGYCEQTDIHSPHVTVYESLLYSAWLRLSPD-INAETRKMFIEEVMELVE-- 145
             + +     Y  + DIH PH+TVY++L+  A L+   + +   TR+ F   V ++    
Sbjct: 230 IKKHYRGEVVYNAEADIHLPHLTVYQTLVTVARLKTPQNRVKGVTREDFANHVTDVAMAT 289

Query: 146 --LKPLRYALVGLPGVSGLSTEQRKRLTVAVELVANPSIIFMDEPTSGLDARAAAIVMRA 203
             L   R   VG   V G+S  +RKR+++A   +        D  T GLD+  A   +RA
Sbjct: 290 YGLSHTRDTKVGNDLVRGVSGGERKRVSIAEVWICGSKFQCWDNATRGLDSATALEFVRA 349

Query: 204 VRNTVDTGRTVVCT-IHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNSSNLINYFEGVQ 262
           ++      + V    I+Q S D +  F+++ +L +G Q IY G   H             
Sbjct: 350 LKTQAHIAKNVATVAIYQCSQDAYNLFNKVSVLYEGYQ-IYFGDAQHAKVYFQKMGYFCP 408

Query: 263 GVSKIKDGYNPATWMLE-------VTTSSKEVELRIDYAEVYKNSELYRRNKALIKELSA 315
               I D     T   E       +    K  +  +D  E + NSE Y++ +  I E  A
Sbjct: 409 KRQTIPDFLTSITSPAERRINKEYLDKGIKVPQTPLDMVEYWHNSEEYKQLREEIDETLA 468

Query: 316 P--------------APCSKDLYFPSRYSRSFFTQCIACLWKQHWSYWRNPEYNAIRFLY 361
                          A  SK     S Y  S+  Q    L +  W    +      +   
Sbjct: 469 HQSEDDKEEIKEAHIAKQSKRARPSSPYVVSYMMQVKYILIRNFWRIKNSASVTLFQVFG 528

Query: 362 STAVAVLLGSMFWNLGSKIEK--DQDLFNAMGSMYAAVILIGAMNSNSVQPVVGVERTVF 419
           ++A+A +LGSMF+    KI+K    D F   G+     IL  A +S      +   R + 
Sbjct: 529 NSAMAFILGSMFY----KIQKGSSADTFYFRGAAMFFAILFNAFSSLLEIFSLYEARPIT 584

Query: 420 YRERAARMYSAFPYALAQVVIQLPYVFVQAVVYGIVVYVMIGFEWTLVKVVWCLFFMYFT 479
            + R   +Y     A A V+ ++P   V A+++ I+ Y ++ F     +     FF YF 
Sbjct: 585 EKHRTYSLYHPSADAFASVISEIPPKIVTAILFNIIFYFLVNFRRDAGR-----FFFYFL 639

Query: 480 FLYFTFYGMMSV-----AMTPNNHISIIVSSAFYSVWNLFSGFVLPRPGK**LISVILSI 534
                 + M  +     ++T     +++ +S      ++++GF +PR            +
Sbjct: 640 INVIAVFAMSHLFRCVGSLTKTLQEAMVPASMLLLALSMYTGFAIPR----------TKM 689

Query: 535 PVWWRWYSWANPVAWSLYGLVTSQYGD 561
             W +W  + NP+A+    L+ +++ D
Sbjct: 690 LGWSKWIWYINPLAYLFESLMVNEFHD 716


>PDRA_YEAST (P51533) ATP-dependent permease PDR10
          Length = 1564

 Score =  263 bits (673), Expect = 8e-70
 Identities = 162/503 (32%), Positives = 263/503 (52%), Gaps = 26/503 (5%)

Query: 37   LLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKTGGYIGGNITISGYPKKQETFARI 96
            +L  + G  +PG LTAL+G +GAGKTTL+D L+ R T G I G++ + G P+ Q +F R 
Sbjct: 941  ILDNVDGWVKPGTLTALIGASGAGKTTLLDCLAERTTMGLITGDVFVDGRPRDQ-SFPRS 999

Query: 97   SGYCEQTDIHSPHVTVYESLLYSAWLRLSPDINAETRKMFIEEVMELVELKPLRYALVGL 156
             GYC+Q D+H    TV ESL +SA+LR + D++ E +  ++EEV+E++E+K    A+VG+
Sbjct: 1000 IGYCQQQDLHLKTATVRESLRFSAYLRQADDVSIEEKDKYVEEVIEVLEMKLYADAIVGV 1059

Query: 157  PGVSGLSTEQRKRLTVAVELVANPSI-IFMDEPTSGLDARAAAIVMRAVRNTVDTGRTVV 215
            PG  GL+ EQRKRLT+ VEL A P + +F+DEPTSGLD++ A    + ++     G+ ++
Sbjct: 1060 PG-EGLNVEQRKRLTIGVELAAKPKLLVFLDEPTSGLDSQTAWSTCQLMKKLASRGQAIL 1118

Query: 216  CTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNSSNLINYFEGVQGVSKIKDGYNPAT 275
            CTIHQPS  + + FD LL L++GGQ +Y G LG     +INYFE   G  K     NPA 
Sbjct: 1119 CTIHQPSALLMQEFDRLLFLQEGGQTVYFGELGKGCKTMINYFE-AHGAHKCPPDANPAE 1177

Query: 276  WMLEVTTSSKEVELRIDYAEVYKNSELYRRNKALIKELSAPAPC---SKDLYFPSRYSRS 332
            WMLE+  ++       DY  ++++SE YR  +  +  +    P             ++ S
Sbjct: 1178 WMLEIVGAAPGTHASQDYFAIWRDSEEYREMQKELDWMERELPKRTEGSSNEEQKEFATS 1237

Query: 333  FFTQCIACLWKQHWSYWRNPEYNAIRFLYSTAVAVLLGSMFWNLGSKIEKDQDLFNAMGS 392
               Q     ++    YWR P Y   +F  +    + +G  F+   + +   Q L N M +
Sbjct: 1238 TLYQIKLVSYRLFHQYWRTPFYLWSKFFSTIVSELFIGFTFFKANTSL---QGLQNQMLA 1294

Query: 393  MYAAVILIGAMNSNSVQPVVGVERTVFYRERAARMYSAFPYALAQVVIQLPYVFVQAVVY 452
            ++   ++   +    +   V        RER +R +S   + ++Q+++++P+  +   + 
Sbjct: 1295 IFMFTVVFNPILQQYLPLFVQQRELYEARERPSRTFSWKAFIVSQILVEIPWNLLAGTIA 1354

Query: 453  GIVVYVMIGF------------EWTLVKVVWCLFFMYFTFLYFTFYGMMSVAMTPNNHIS 500
              V Y  +GF               L  +  C F++Y + +       + +A    N  S
Sbjct: 1355 FFVYYYPVGFYRNASYANQLHERGALFWLFACAFYVYISSMGVLVISCIEIAENAANLAS 1414

Query: 501  I--IVSSAFYSVWNLFSGFVLPR 521
            +  I+S +F  V  L +  +LPR
Sbjct: 1415 LFFIMSLSFCGV--LATPNILPR 1435



 Score =  117 bits (293), Expect = 9e-26
 Identities = 135/579 (23%), Positives = 238/579 (40%), Gaps = 69/579 (11%)

Query: 26  RNRGVIEDK---LVLLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKTGGYIGGN-- 80
           R  G  ED      +LK + G   PG L  ++G  GAG TTL+  +S    G  I  +  
Sbjct: 181 RTHGKSEDNDSGFQILKPMDGCINPGELLVVLGRPGAGCTTLLKSISVNTHGFKISPDTI 240

Query: 81  ITISGYPKKQ--ETFARISGYCEQTDIHSPHVTVYESLLYSAWLRLSPD----INAET-R 133
           IT +G+  K+    +     Y  ++DIH PH+TV+++L   A L+   +    ++ +T  
Sbjct: 241 ITYNGFSNKEIKNHYRGEVVYNAESDIHIPHLTVFQTLYTVARLKTPRNRIKGVDRDTFA 300

Query: 134 KMFIEEVMELVELKPLRYALVGLPGVSGLSTEQRKRLTVAVELVANPSIIFMDEPTSGLD 193
           K   E  M    L       VG   V G+S  +RKR+++A   +        D  T GLD
Sbjct: 301 KHMTEVAMATYGLSHTADTKVGNDFVRGVSGGERKRVSIAEVSICGSKFQCWDNATRGLD 360

Query: 194 ARAAAIVMRAVRNTVD-TGRTVVCTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNSS 252
           +  A   ++A++     T       I+Q S D ++ FD++ +L  G Q I+ GP    S 
Sbjct: 361 SATALEFIKALKTQATITKSAATVAIYQCSKDAYDLFDKVCVLYDGYQ-IFFGP----SK 415

Query: 253 NLINYFEGVQGVSKIKDGYNPATWMLEVTTSSKEV-------------ELRIDYAEVYKN 299
               YF+ +  V   +     A ++  +T+ S+ +             +   +  + +  
Sbjct: 416 QAKKYFQRMGYVCPERQ--TTADYLTSITSPSERIKDKDMVKHGIMIPQTAYEMNQYWIQ 473

Query: 300 SELYRR-----NKALIKELSAPAPCSKDLYFP---------SRYSRSFFTQCIACLWKQH 345
           SE Y++     NK L  + S      K+ +           S Y+ SFF Q    L +  
Sbjct: 474 SEEYKQLQVQVNKHLDTDSSQQREQIKNAHIAKQSKRARPSSPYTVSFFLQVKYILIRDI 533

Query: 346 WSYWRNPEYNAIRFLYSTAVAVLLGSMFWNLGSKIEKDQDLFNAMGSMYAAVILIGAMNS 405
           W    +P       L   A+A++LGSMF+ +   +      F   G+     IL  A +S
Sbjct: 534 WRIKNDPSIQLFTVLSHAAMALILGSMFYEV--MLSTTTTTFYYRGAAIFFAILFNAFSS 591

Query: 406 NSVQPVVGVERTVFYRERAARMYSAFPYALAQVVIQLPYVFVQAVVYGIVVYVMIGFEWT 465
                 +   R +  + +   +Y     A A     +P     AV + I  Y +I     
Sbjct: 592 LLEIFSLYETRPITEKHKTYSLYRPSADAFASTFSDVPTKLATAVTFNIPYYFLIN---- 647

Query: 466 LVKVVWCLFFMYFTFLYFTFYGMMSV-----AMTPNNHISIIVSSAFYSVWNLFSGFVLP 520
            +K     FF YF     T + M  +     +++     +++ +S     + +++GF +P
Sbjct: 648 -LKRDAGAFFFYFLINIITVFAMSHLFRCIGSVSKTLPQAMVPASVLLLAFAMYTGFAIP 706

Query: 521 RPGK**LISVILSIPVWWRWYSWANPVAWSLYGLVTSQY 559
           R          + +  W +W S+ NP+++    L+ +++
Sbjct: 707 R----------VQMLGWSKWISYINPLSYLFESLMINEF 735


>PDRF_YEAST (Q04182) ATP-dependent permease PDR15
          Length = 1529

 Score =  263 bits (671), Expect = 1e-69
 Identities = 160/479 (33%), Positives = 257/479 (53%), Gaps = 28/479 (5%)

Query: 37   LLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKTGGYIGGNITISGYPKKQETFARI 96
            +L  + G  +PG LTALMG +GAGKTTL+D L+ R T G I GNI + G   + E+F R 
Sbjct: 902  ILNNVDGWVKPGTLTALMGASGAGKTTLLDCLAERVTMGVITGNIFVDGR-LRDESFPRS 960

Query: 97   SGYCEQTDIHSPHVTVYESLLYSAWLRLSPDINAETRKMFIEEVMELVELKPLRYALVGL 156
             GYC+Q D+H    TV ESL +SA+LR    ++ E +  ++EEV++++E++    A+VG+
Sbjct: 961  IGYCQQQDLHLKTATVRESLRFSAYLRQPSSVSIEEKNRYVEEVIKILEMQQYSDAVVGV 1020

Query: 157  PGVSGLSTEQRKRLTVAVELVANPSI-IFMDEPTSGLDARAAAIVMRAVRNTVDTGRTVV 215
             G  GL+ EQRKRLT+ VEL A P + +F+DEPTSGLD++ A    + +R     G+ ++
Sbjct: 1021 AG-EGLNVEQRKRLTIGVELAARPKLLVFLDEPTSGLDSQTAWDTCQLMRKLATHGQAIL 1079

Query: 216  CTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNSSNLINYFEGVQGVSKIKDGYNPAT 275
            CTIHQPS  + + FD LL L++GGQ +Y G LG     +I+YFE  +G  K     NPA 
Sbjct: 1080 CTIHQPSAILMQQFDRLLFLQKGGQTVYFGDLGEGCKTMIDYFES-KGAHKCPPDANPAE 1138

Query: 276  WMLEVTTSSKEVELRIDYAEVYKNSELYRRNKALIKELS---------APAPCSKDLYFP 326
            WMLEV  ++       DY EV++NS+ Y   KA+ +EL          +  P +++    
Sbjct: 1139 WMLEVVGAAPGSHATQDYNEVWRNSDEY---KAVQEELDWMEKNLPGRSKEPTAEE---H 1192

Query: 327  SRYSRSFFTQCIACLWKQHWSYWRNPEYNAIRFLYSTAVAVLLGSMFWNLGSKIEKDQDL 386
              ++ S + Q      +    YWR+P+Y   +F+ +    V +G  F+     +   Q L
Sbjct: 1193 KPFAASLYYQFKMVTIRLFQQYWRSPDYLWSKFILTIFNQVFIGFTFFKADRSL---QGL 1249

Query: 387  FNAMGSMYAAVILIGAMNSNSVQPVVGVERTVFYRERAARMYSAFPYALAQVVIQLPYVF 446
             N M S++   ++   +    +   V        RER +R +S   + L+Q+++++P+  
Sbjct: 1250 QNQMLSIFMYTVIFNPILQQYLPSFVQQRDLYEARERPSRTFSWLAFFLSQIIVEIPWNI 1309

Query: 447  VQAVVYGIVVYVMIGFEWTLVKVVWCL-----FFMYFTFLYFTFYGMMSVAMTPNNHIS 500
            +   +   + Y  +GF +        L      F  F+  ++ + G M + M   N ++
Sbjct: 1310 LAGTIAYCIYYYAVGF-YANASAAGQLHERGALFWLFSIAFYVYIGSMGLLMISFNEVA 1367



 Score =  121 bits (303), Expect = 6e-27
 Identities = 141/649 (21%), Positives = 262/649 (39%), Gaps = 97/649 (14%)

Query: 32  EDKLVLLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKTGGYIGGNITIS----GYP 87
           ED   +LK + G   PG L  ++G  G+G TTL+  +S    G  I  +  +S       
Sbjct: 180 EDTFQILKPMDGCLNPGELLVVLGRPGSGCTTLLKSISSNSHGFKIAKDSIVSYNGLSSS 239

Query: 88  KKQETFARISGYCEQTDIHSPHVTVYESLLYSAWLRLSPD-INAETRKMFIEEVMELVE- 145
             ++ +     Y  ++DIH PH+TVY++L   A ++   + I    R+ +   V E+   
Sbjct: 240 DIRKHYRGEVVYNAESDIHLPHLTVYQTLFTVARMKTPQNRIKGVDREAYANHVTEVAMA 299

Query: 146 ---LKPLRYALVGLPGVSGLSTEQRKRLTVAVELVANPSIIFMDEPTSGLDARAAAIVMR 202
              L   R   VG   V G+S  +RKR+++A   +        D  T GLD+  A   +R
Sbjct: 300 TYGLSHTRDTKVGNDLVRGVSGGERKRVSIAEVAICGARFQCWDNATRGLDSATALEFIR 359

Query: 203 AVRNTVDTGRT-VVCTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNSSNLINYFEGV 261
           A++   D G+T     I+Q S D ++ FD++ +L  G Q +Y GP    + +   YF+ +
Sbjct: 360 ALKTQADIGKTAATVAIYQCSQDAYDLFDKVCVLDDGYQ-LYFGP----AKDAKKYFQDM 414

Query: 262 QGVSKIKDGYNPATWMLEVTTSSKEV-------------ELRIDYAEVYKNSELYRRNKA 308
                 +     A ++  +T+ ++ +             +   D AE +  SE Y   K 
Sbjct: 415 GYYCPPRQ--TTADFLTSITSPTERIISKEFIEKGTRVPQTPKDMAEYWLQSESY---KN 469

Query: 309 LIKELSAP-----------------APCSKDLYFPSRYSRSFFTQCIACLWKQHWSYWRN 351
           LIK++ +                  A  +K     S Y  ++  Q    L +  W   ++
Sbjct: 470 LIKDIDSTLEKNTDEARNIIRDAHHAKQAKRAPPSSPYVVNYGMQVKYLLIRNFWRMKQS 529

Query: 352 PEYNAIRFLYSTAVAVLLGSMFWNLGSKIEKDQDLFNAMGSMYAAVILIGAMNSNSVQPV 411
                 + + ++ +A +LGSMF+ +  K   D   F   G+     IL  A +       
Sbjct: 530 ASVTLWQVIGNSVMAFILGSMFYKVMKK--NDTSTFYFRGAAMFFAILFNAFSCLLEIFS 587

Query: 412 VGVERTVFYRERAARMYSAFPYALAQVVIQLPYVFVQAVVYGIVVYVMIGFEWTLVKVVW 471
           +   R +  + R   +Y     A A V+ ++P   + AV + I+ Y ++ F         
Sbjct: 588 LYETRPITEKHRTYSLYHPSADAFASVLSEMPPKLITAVCFNIIFYFLVDFRRN-----G 642

Query: 472 CLFFMYFTFLYFTFYGMMSV-----AMTPNNHISIIVSSAFYSVWNLFSGFVLPRPGK** 526
            +FF YF       + +  +     ++T     +++ +S      ++++GF +P+     
Sbjct: 643 GVFFFYFLINVIATFTLSHLFRCVGSLTKTLQEAMVPASMLLLAISMYTGFAIPK----- 697

Query: 527 LISVILSIPVWWRWYSWANPVAWSLYGLVTSQYGDVK----QNIETSDGRQTV------- 575
                  I  W  W  + NP+A+    L+ +++ D +    Q I      Q +       
Sbjct: 698 -----TKILGWSIWIWYINPLAYLFESLMINEFHDRRFPCAQYIPAGPAYQNITGTQRVC 752

Query: 576 --------------EDFLRNYFGFKHDFLGVVALVNIAFPIVFALVFAI 610
                         +DFL+  + ++H        + +A+ + F  V+ I
Sbjct: 753 SAVGAYPGNDYVLGDDFLKESYDYEHKHKWRGFGIGMAYVVFFFFVYLI 801


>SNQ2_YEAST (P32568) SNQ2 protein
          Length = 1501

 Score =  248 bits (634), Expect = 3e-65
 Identities = 171/530 (32%), Positives = 283/530 (53%), Gaps = 27/530 (5%)

Query: 34   KLVLLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKTGGYIGGNITISGYPKKQETF 93
            K +LL  +SG   PG +TALMG +GAGKTTL++ L+ R  G  I G++ ++G P    +F
Sbjct: 868  KRMLLDNVSGYCIPGTMTALMGESGAGKTTLLNTLAQRNVG-IITGDMLVNGRPI-DASF 925

Query: 94   ARISGYCEQTDIHSPHVTVYESLLYSAWLRLSPDINAETRKMFIEEVMELVELKPLRYAL 153
             R +GY +Q DIH   +TV ESL +SA +R    +    +  ++E+++ ++ ++    AL
Sbjct: 926  ERRTGYVQQQDIHIAELTVRESLQFSARMRRPQHLPDSEKMDYVEKIIRVLGMEEYAEAL 985

Query: 154  VGLPGVSGLSTEQRKRLTVAVELVANPSII-FMDEPTSGLDARAAAIVMRAVRNTVDTGR 212
            VG  G  GL+ EQRK+L++ VELVA P ++ F+DEPTSGLD++++  +++ +R     G+
Sbjct: 986  VGEVGC-GLNVEQRKKLSIGVELVAKPDLLLFLDEPTSGLDSQSSWAIIQLLRKLSKAGQ 1044

Query: 213  TVVCTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNSSNLINYFEGVQGVSKIKDGYN 272
            +++CTIHQPS  +FE FD LLLL++GGQ +Y G +G NS+ ++NYFE   G  K     N
Sbjct: 1045 SILCTIHQPSATLFEEFDRLLLLRKGGQTVYFGDIGKNSATILNYFER-NGARKCDSSEN 1103

Query: 273  PATWMLEVTTSSKEVELRIDYAEVYKNSELYRRNKA----LIKELSAPAPCSKDLYFPSR 328
            PA ++LE   +     ++ D+ E + NS  + + K     LI +LS     S+    PS+
Sbjct: 1104 PAEYILEAIGAGATASVKEDWHEKWLNSVEFEQTKEKVQDLINDLSKQETKSEVGDKPSK 1163

Query: 329  YSRSFFTQCIACLWKQHWSYWRNPEYNAIRFLYSTAVAVLLGSMFWNLGSKIEKDQDLFN 388
            Y+ S+  Q    L +   S+WR+  Y   + +      + +G  F+N+G        L N
Sbjct: 1164 YATSYAYQFRYVLIRTSTSFWRSLNYIMSKMMLMLVGGLYIGFTFFNVGKSY---VGLQN 1220

Query: 389  AMGSMYAAVILIGAMNSNSVQPVVGVERTVF-YRERAARMYSAFPYALAQVVIQLPYVFV 447
            AM + + ++IL  A   N +Q      R +F  RE  + M+      + Q + +LPY   
Sbjct: 1221 AMFAAFISIIL-SAPAMNQIQGRAIASRELFEVRESQSNMFHWSLVLITQYLSELPYHLF 1279

Query: 448  QAVVYGIVVY--VMIGFEWTLVKVVWCLFFMYFTFLYFTFYGMMSVAMTPNNHISIIVSS 505
             + ++ +  Y  + I FE +   V +  + + F  LY+   G+M + M+PN   + ++  
Sbjct: 1280 FSTIFFVSSYFPLRIFFEASRSAVYFLNYCIMFQ-LYYVGLGLMILYMSPNLPSANVILG 1338

Query: 506  AFYSVWNLFSGFVLPRPGK**LISVILSIPVWWRWYSWANPVAWSLYGLV 555
               S    F G   P          +  +P +W +   A+P  + +  LV
Sbjct: 1339 LCLSFMLSFCGVTQP----------VSLMPGFWTFMWKASPYTYFVQNLV 1378



 Score =  104 bits (259), Expect = 8e-22
 Identities = 120/568 (21%), Positives = 236/568 (41%), Gaps = 77/568 (13%)

Query: 37  LLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGR--KTGGYIGGNITISGYPKKQETFA 94
           ++  ++     G +  ++G  GAG ++ + V +G   +  G + G +   G P+ +E   
Sbjct: 175 IISNVNALAEAGEMILVLGRPGAGCSSFLKVTAGEIDQFAGGVSGEVAYDGIPQ-EEMMK 233

Query: 95  RISG---YCEQTDIHSPHVTVYESLLYSAWLRLSP-DINAETRKMFIEEVMELVE----L 146
           R      Y  + D+H P++TV ++L ++   +     +N  ++K +I    +L      L
Sbjct: 234 RYKADVIYNGELDVHFPYLTVKQTLDFAIACKTPALRVNNVSKKEYIASRRDLYATIFGL 293

Query: 147 KPLRYALVGLPGVSGLSTEQRKRLTVAVELVANPSIIFMDEPTSGLDARAAAIVMRAVRN 206
           +      VG   V G+S  +RKR+++A  L A  SI   D  T GLDA  A    +A+R 
Sbjct: 294 RHTYNTKVGNDFVRGVSGGERKRVSIAEALAAKGSIYCWDNATRGLDASTALEYAKAIRI 353

Query: 207 TVDTGR-TVVCTIHQPSIDIFESFDELLLLKQGGQEIYVG----------------PLGH 249
             +  + T   TI+Q S +I+E+FD++ +L   G++IY G                P   
Sbjct: 354 MTNLLKSTAFVTIYQASENIYETFDKVTVL-YSGKQIYFGLIHEAKPYFAKMGYLCPPRQ 412

Query: 250 NSSNLINYFEGVQGVSKIKDGYNPATWMLEVTTSSKEVEL----RIDYAEVYKNSELYRR 305
            ++  +       G   IK GY       +V  +++E E       ++A++ K+   Y+ 
Sbjct: 413 ATAEFLTALTDPNGFHLIKPGYEN-----KVPRTAEEFETYWLNSPEFAQMKKDIAAYKE 467

Query: 306 --NKALIKEL---SAPAPCSKDLYFPSRYSRSFFTQCIACLWKQHWSYWRNPEYNAIRFL 360
             N    KE+   S     SK     S Y+ S++ Q   C  +     + N  Y  I   
Sbjct: 468 KVNTEKTKEVYDESMAQEKSKYTRKKSYYTVSYWEQVKLCTQRGFQRIYGNKSYTVINVC 527

Query: 361 YSTAVAVLLGSMFWNLGSKIEKDQDLFNAMGSMYAAVILIGAMNSNSVQPVVGVERTVFY 420
            +   + + GS+F+N  S        F+  G +Y A++    M   ++       R +  
Sbjct: 528 SAIIQSFITGSLFYNTPS---STSGAFSRGGVLYFALLYYSLMGLANIS---FEHRPILQ 581

Query: 421 RERAARMYSAFPYALAQVVIQLPYVFVQAVVYGIVVYVMIGFEWTLVKVVWCLFFMYFTF 480
           + +   +Y     A+   +   P+  +    + I+++ + G   T        FF  + F
Sbjct: 582 KHKGYSLYHPSAEAIGSTLASFPFRMIGLTCFFIILFFLSGLHRTAGS-----FFTIYLF 636

Query: 481 L---------YFTFYGMMSVAMTPNNHISIIVSSAFYSVWNLFSGFVLPRPGK**LISVI 531
           L          F     +   ++  N IS I+  +     +++S +++  P         
Sbjct: 637 LTMCSEAINGLFEMVSSVCDTLSQANSISGILMMSI----SMYSTYMIQLP--------- 683

Query: 532 LSIPVWWRWYSWANPVAWSLYGLVTSQY 559
            S+  W++W S+  P+ ++   ++ +++
Sbjct: 684 -SMHPWFKWISYVLPIRYAFESMLNAEF 710


>CDR3_CANAL (O42690) Opaque-specific ABC transporter CDR3
          Length = 1501

 Score =  248 bits (634), Expect = 3e-65
 Identities = 167/546 (30%), Positives = 278/546 (50%), Gaps = 39/546 (7%)

Query: 33   DKLVLLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKTGGYIGGNITISGYPKKQET 92
            ++ V+L  + G  +PG +TALMG +GAGKTTL++ LS R T G I     +    +   +
Sbjct: 854  EERVILNNIDGWVKPGEVTALMGASGAGKTTLLNALSERLTTGVITSGTRMVNGGELDSS 913

Query: 93   FARISGYCEQTDIHSPHVTVYESLLYSAWLRLSPDINAETRKMFIEEVMELVELKPLRYA 152
            F R  GY +Q D+H    TV E+L +SA LR    ++   +  ++E++++L+E++    A
Sbjct: 914  FQRSIGYVQQQDLHLETSTVREALKFSARLRQPNSVSIAEKDSYVEKIIDLLEMRTYVDA 973

Query: 153  LVGLPGVSGLSTEQRKRLTVAVELVANPS-IIFMDEPTSGLDARAAAIVMRAVRNTVDTG 211
            +VG+PG  GL+ EQRKRLT+AVELVA P  ++F+DEPTSGLD++ A  + + +R   + G
Sbjct: 974  IVGVPG-EGLNVEQRKRLTIAVELVARPKLLVFLDEPTSGLDSQTAWSICKLIRKLANHG 1032

Query: 212  RTVVCTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNSSNLINYFEGVQGVSKIKDGY 271
            + ++CTIHQPS  + E FD LLLL Q G+ +Y G  G N   LI YFE   G SK     
Sbjct: 1033 QAILCTIHQPSAILLEEFDRLLLL-QKGETVYFGEFGANCHTLIEYFER-NGASKCPQHA 1090

Query: 272  NPATWMLEVTTSSKEVELRIDYAEVYKNSELYR---RNKALIKELSAPAPCSKDLYFPSR 328
            NPA WML V  ++   +   DY E ++NS  YR        ++E+   A   K+      
Sbjct: 1091 NPAEWMLGVIGAAPGTQANQDYFETWRNSPEYRAVQNELHRLEEMPGLASGEKEPDTNQA 1150

Query: 329  YSRSFFTQCIACLWKQHWSYWRNPEYNAIRFLYSTAVAVLLGSMFWNLGSKIEKDQDLFN 388
            Y+ SF+ Q I  + +    YWR P Y   +F  +   ++  G  ++   + +   Q L N
Sbjct: 1151 YAASFWKQYIFVVHRLFQQYWRTPSYIYSKFAMAVLCSLFNGFTYYKSQNSM---QGLKN 1207

Query: 389  AMGSMYAAVILIGAMNSNSVQPVVGVERTVF-YRERAARMYSAFPYALAQVVIQLPYVFV 447
             M S+++  +++  +    V P+   +R ++  RER ++ +S   +  AQ+  ++PY  +
Sbjct: 1208 QMLSIFSMFVVLTTLAQQYV-PLFVTQRDLYEARERPSKTFSWLAFIAAQITAEIPYQVL 1266

Query: 448  QAVVYGIVVYVMIGF------------EWTLVKVVWCLFFMYFTFLYFTFYGMMSVAMTP 495
             A +     Y  +G                L+ ++  L F+Y + L         +A   
Sbjct: 1267 AATISFFSWYYPVGLYRNAVYSGAVTHRGVLMWLIMTLMFIYSSTLAQFCISWNQLADYA 1326

Query: 496  NNHISIIVSSAFYSVWNLFSGFVLPRPGK**LISVILSIPVWWRWYSWANPVAWSLYGLV 555
             N IS++++ +      +F G +  +           S+P +W +     P+ +    ++
Sbjct: 1327 ANWISLLLTISM-----IFCGVIATKD----------SMPKFWVFLYRCTPLTYLTSAMM 1371

Query: 556  TSQYGD 561
            +   GD
Sbjct: 1372 SIGLGD 1377



 Score =  127 bits (319), Expect = 9e-29
 Identities = 129/572 (22%), Positives = 249/572 (42%), Gaps = 84/572 (14%)

Query: 37  LLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKTGGYIGGNITISGYPKKQETFAR- 95
           +LK + G  +PG +T ++G  GAG +T +  ++ R  G ++     IS     Q+     
Sbjct: 160 ILKPMEGLIKPGEVTVVLGRPGAGCSTFLKTIACRTEGFHVADGSVISYDGITQDEIRNH 219

Query: 96  ISG---YCEQTDIHSPHVTVYESLLYSAWLRLSPD-----INAETRKMFIEEVMELVELK 147
           + G   YC +T+ H P++TV E+L ++A ++   +        E  K  ++ VM    L 
Sbjct: 220 LRGEVVYCAETETHFPNLTVGETLEFAALMKTPQNRPMGVSREEYAKHVVDVVMATYGLS 279

Query: 148 PLRYALVGLPGVSGLSTEQRKRLTVAVELVANPSIIFMDEPTSGLDARAAAIVMRAVRNT 207
             +   VG   + G+S  +RKRL++A   +   SI   D  T GLDA  A   + +++ +
Sbjct: 280 HTKNTKVGNDFIRGISGGERKRLSIAEVTLVQASIQCWDNSTRGLDAATALEFISSLKTS 339

Query: 208 VD-TGRTVVCTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNSSNLINYFEGVQGVSK 266
                 T +  I+Q S + ++ FD+++++ +G Q I+ G    +S     YF+ +  V +
Sbjct: 340 ASILNDTPLIAIYQCSQNAYDLFDKVIVMYEGYQ-IFFG----SSQRAAAYFKKMGFVCQ 394

Query: 267 -------------------IKDGY------NPATWMLEVTTSSKEVELRIDYAEVYKNSE 301
                              IK GY       P  +      S +   L  +  E   N E
Sbjct: 395 DRQTTPDFLTSITSPAERIIKPGYERLVPRTPKEFYRYWRRSPERQALLEEIDEYLDNCE 454

Query: 302 LYRRNKALIKELSAPAPCSKDLYFPSRYSRSFFTQCIACLWKQHWSYWRNPEYNAIRFLY 361
            Y + + + +  +A    +K  Y  S Y+ S   Q +  + K++W   R      +  + 
Sbjct: 455 NYDQKQKIFEANNAKK--AKHTYNKSSYTVSLPMQ-VRYIMKRYWDRMRGDIIVPLSTVA 511

Query: 362 -STAVAVLLGSMFWNLGSKIEKDQDLFNAMGSMYAAVILIGAMNSNSVQPVVGV-----E 415
            + A+A++L S+F+NL           N+    Y   ++  A+  N+   V+ +      
Sbjct: 512 GNIAMALILSSVFYNLQP---------NSSSFYYRTSVMYYALLFNAYSSVLEIYNMYEG 562

Query: 416 RTVFYRERAARMYSAFPYALAQVVIQLPYVFVQAVVYGIVVYVMIGFE--------WTLV 467
           R +  + R   +Y     A+  ++   P   V +V++ +++Y M+ F+        + L+
Sbjct: 563 RAIVQKHREYALYPPMADAIGSIISDFPLKVVCSVLFNLILYFMVNFKREPGAFFFYLLI 622

Query: 468 KVVWCLFFMYFTFLYFTFYGMMSVAMTPNNHISIIVSSAFYSVWNLFSGFVLPRPGK**L 527
                LF  +       F   ++ AMTP++ +   +S+        FSGF +P       
Sbjct: 623 SFCSTLFMSHLFRTIGAFTNSLAEAMTPSSLLLFALST--------FSGFAIP------- 667

Query: 528 ISVILSIPVWWRWYSWANPVAWSLYGLVTSQY 559
           ++ +L    W +W  W NP+A++   L+++++
Sbjct: 668 VTYMLG---WCKWIRWVNPLAYAYEALISNEF 696


>CDR2_CANAL (P78595) Multidrug resistance protein CDR2
          Length = 1499

 Score =  243 bits (620), Expect = 1e-63
 Identities = 173/566 (30%), Positives = 285/566 (49%), Gaps = 45/566 (7%)

Query: 14   EVSYSVDMPQEMRNRGVIEDKLVLLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKT 73
            +++Y V + +E R         V+L  + G  +PG +TALMG +GAGKTTL++ LS R T
Sbjct: 861  DLTYQVKIKKEDR---------VILDHVDGWVKPGQITALMGASGAGKTTLLNCLSERVT 911

Query: 74   GGYI-GGNITISGYPKKQETFARISGYCEQTDIHSPHVTVYESLLYSAWLRLSPDINAET 132
             G I  G   ++G+     +F R  GY +Q D+H    TV E+L +SA+LR S  I+ + 
Sbjct: 912  TGIITDGERLVNGHAL-DSSFQRSIGYVQQQDVHLETTTVREALQFSAYLRQSNKISKKE 970

Query: 133  RKMFIEEVMELVELKPLRYALVGLPGVSGLSTEQRKRLTVAVELVANPSII-FMDEPTSG 191
            +  +++ V++L+E+     ALVG+ G  GL+ EQRKRLT+ VELVA P ++ F+DEPTSG
Sbjct: 971  KDDYVDYVIDLLEMTDYADALVGVAG-EGLNVEQRKRLTIGVELVAKPKLLLFLDEPTSG 1029

Query: 192  LDARAAAIVMRAVRNTVDTGRTVVCTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNS 251
            LD++ A  + + +R   D G+ ++CTIHQPS  I   FD+LL L++GG+  Y G LG N 
Sbjct: 1030 LDSQTAWSICKLMRKLADHGQAILCTIHQPSALIMAEFDKLLFLQKGGRTAYFGELGENC 1089

Query: 252  SNLINYFEGVQGVSKIKDGYNPATWMLEVTTSSKEVELRIDYAEVYKNSELYRRNKALIK 311
              +INYFE   G        NPA WML+V  ++     + DY EV++NS  Y+  +  I 
Sbjct: 1090 QTMINYFE-KYGADPCPKEANPAEWMLQVVGAAPGSHAKQDYFEVWRNSSEYQAVREEIN 1148

Query: 312  ELSA---PAPCSKDLYFPSRYSRSFFTQCIACLWKQHWSYWRNPEYNAIRFLYSTAVAVL 368
             + A     P   D     +Y+   + Q +   W+     WR+P Y     +YS  + V+
Sbjct: 1149 RMEAELSKLPRDNDPEALLKYAAPLWKQYLLVSWRTIVQDWRSPGY-----IYSKLILVI 1203

Query: 369  LGSMFWNLGSKIEKDQDLFNAMGSMYAAVILIGAMNSNSVQ---PVVGVERTVF-YRERA 424
              S+F  +G    K ++    + S   AV +     +  +    P     R V+  RE  
Sbjct: 1204 SSSLF--IGFSFFKSKNNLQGLQSQMLAVFMFFVPFTTFIDQMLPYFVKHRAVYEVREAP 1261

Query: 425  ARMYSAFPYALAQVVIQLPYVFVQAVVYGIVVYVMIGF-----EWTLVKVVWCLFFMYFT 479
            +R +S F +   Q+  ++P+  V   +     Y  +G          V     L +M  T
Sbjct: 1262 SRTFSWFAFIAGQITSEIPFQIVVGTISYFCWYYPVGLYANAEPTDSVNSRGVLMWMLLT 1321

Query: 480  --FLYFTFYGMMSVAMTPNNHISIIVSSAFYSVWNLFSGFVLPRPGK**LISVILSIPVW 537
              ++Y +  G +++++      +  +++  +++  +F G VL  P           IP +
Sbjct: 1322 AFYVYTSTMGQLAISLNELIDNAANLATTLFTLCLMFCG-VLAGPN---------VIPGF 1371

Query: 538  WRWYSWANPVAWSLYGLVTSQYGDVK 563
            W +    NP  + +  ++++   + K
Sbjct: 1372 WIFMYRCNPFTYLIQAILSTGLANAK 1397



 Score =  127 bits (320), Expect = 7e-29
 Identities = 143/560 (25%), Positives = 234/560 (41%), Gaps = 60/560 (10%)

Query: 37  LLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKTGGYIG--GNITISGY-PKKQETF 93
           +LK +    RPG LT ++G  GAG +TL+  ++    G +IG    IT  G  P   E  
Sbjct: 167 ILKSMDAIMRPGELTVVLGRPGAGCSTLLKTIAVNTYGFHIGKESQITYDGLSPHDIERH 226

Query: 94  ARISG-YCEQTDIHSPHVTVYESLLYSAWLRLSPD----INAETRKMFIEEV-MELVELK 147
            R    Y  +TD+H PH++V ++L ++A LR   +    I+ ET    +  V M    L 
Sbjct: 227 YRGDVIYSAETDVHFPHLSVGDTLEFAARLRTPQNRGEGIDRETYAKHMASVYMATYGLS 286

Query: 148 PLRYALVGLPGVSGLSTEQRKRLTVAVELVANPSIIFMDEPTSGLDARAAAIVMRAVRNT 207
             R   VG   V G+S  +RKR+++A   ++  +I   D  T GLD+  A   +RA++ +
Sbjct: 287 HTRNTNVGNDFVRGVSGGERKRVSIAEASLSGANIQCWDNATRGLDSATALEFIRALKTS 346

Query: 208 ---VDTGRTVVCTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNSSNLINYFEGVQGV 264
              +DT  T +  I+Q S D +E FD +++L +G Q I+ G     +S    YFE +   
Sbjct: 347 ATILDT--TPLIAIYQCSQDAYELFDNVVVLYEGYQ-IFFG----KASKAKEYFENMGW- 398

Query: 265 SKIKDGYNPATWMLEVTTSSKEVEL--------------------RIDYAEVYKNSELY- 303
            K       A ++  +T  ++   L                      +YAE+ K  + Y 
Sbjct: 399 -KCPQRQTTADFLTSLTNPAEREPLPGYEDKVPRTAQEFETFWKNSPEYAELTKEIDEYF 457

Query: 304 ----RRNKALIKELSAPAPCSKDLYFPSRYSRSFFTQCIACLWKQHWSYWRNPEYNAIRF 359
               R N       S     S +    S Y+ SFF Q    + +       +P    I  
Sbjct: 458 VECERSNTGETYRESHVGKQSNNTRPSSPYTVSFFMQVRYVIARNFLRMKGDPSIPLISI 517

Query: 360 LYSTAVAVLLGSMFWNLGSKIEKDQDLFNAMGSMYAAVILIGAMNSNSVQPVVGVERTVF 419
           L    + ++L S+F+NL     K  D F   G      +L  A +S      +   R + 
Sbjct: 518 LSQLVMGLILASVFFNL----RKSTDTFYFRGGALFFSVLFNAFSSLLEILSLYEARPIV 573

Query: 420 YRERAARMYSAFPYALAQVVIQLPYVFVQAVVYGIVVYVMIGFEWTLVKVVWCLFFMYFT 479
            + R   +Y     ALA ++ +LP   +  + + IV Y M+    T     +        
Sbjct: 574 EKHRKYALYRPSADALASIISELPVKLLMTMSFNIVYYFMVNLRRTAGNFFFYWLMCASC 633

Query: 480 FLYFTFYGMMSVAMTPNNHISIIVSSAFYSVWNLFSGFVLPRPGK**LISVILSIPVWWR 539
            L  +       A+T     ++ +S+ F     +++GFVLP P           I  W R
Sbjct: 634 TLVMSHMFRSIGAVTTTIATAMSLSTVFLLAMIIYAGFVLPIP----------YILGWSR 683

Query: 540 WYSWANPVAWSLYGLVTSQY 559
           W  + NPV +    L+ +++
Sbjct: 684 WIRYINPVTYIFESLMVNEF 703


>CDR1_CANAL (P43071) Multidrug resistance protein CDR1
          Length = 1501

 Score =  239 bits (609), Expect = 2e-62
 Identities = 154/453 (33%), Positives = 236/453 (51%), Gaps = 20/453 (4%)

Query: 14   EVSYSVDMPQEMRNRGVIEDKLVLLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKT 73
            +++Y V + +E R         V+L  + G  +PG +TALMG +GAGKTTL++ LS R T
Sbjct: 863  DLTYQVKIKKEDR---------VILDHVDGWVKPGQITALMGASGAGKTTLLNCLSERVT 913

Query: 74   GGYI-GGNITISGYPKKQETFARISGYCEQTDIHSPHVTVYESLLYSAWLRLSPDINAET 132
             G I  G   ++G+     +F R  GY +Q D+H P  TV E+L +SA+LR S  I+ + 
Sbjct: 914  TGIITDGERLVNGHAL-DSSFQRSIGYVQQQDVHLPTSTVREALQFSAYLRQSNKISKKE 972

Query: 133  RKMFIEEVMELVELKPLRYALVGLPGVSGLSTEQRKRLTVAVELVANPSII-FMDEPTSG 191
            +  +++ V++L+E+     ALVG+ G  GL+ EQRKRLT+ VELVA P ++ F+DEPTSG
Sbjct: 973  KDDYVDYVIDLLEMTDYADALVGVAG-EGLNVEQRKRLTIGVELVAKPKLLLFLDEPTSG 1031

Query: 192  LDARAAAIVMRAVRNTVDTGRTVVCTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNS 251
            LD++ A  + + +R   D G+ ++CTIHQPS  I   FD LL L++GG+  Y G LG N 
Sbjct: 1032 LDSQTAWSICKLMRKLADHGQAILCTIHQPSALIMAEFDRLLFLQKGGRTAYFGELGENC 1091

Query: 252  SNLINYFEGVQGVSKIKDGYNPATWMLEVTTSSKEVELRIDYAEVYKNSELYRRNKALIK 311
              +INYFE   G        NPA WML+V  ++     + DY EV++NS  Y+  +  I 
Sbjct: 1092 QTMINYFE-KYGADPCPKEANPAEWMLQVVGAAPGSHAKQDYFEVWRNSSEYQAVREEIN 1150

Query: 312  ELSA---PAPCSKDLYFPSRYSRSFFTQCIACLWKQHWSYWRNPEYNAIRFLYSTAVAVL 368
             + A     P   D     +Y+   + Q +   W+     WR+P Y   +     + A+ 
Sbjct: 1151 RMEAELSKLPRDNDPEALLKYAAPLWKQYLLVSWRTIVQDWRSPGYIYSKIFLVVSAALF 1210

Query: 369  LGSMFWNLGSKIEKDQDLFNAMGSMYAAVILIGAMNSNSVQPVVGVERTVFYRERAARMY 428
             G  F+   + +   Q L N M S++   I    +    +   V        RE  +R +
Sbjct: 1211 NGFSFFKAKNNM---QGLQNQMFSVFMFFIPFNTLVQQMLPYFVKQRDVYEVREAPSRTF 1267

Query: 429  SAFPYALAQVVIQLPYVFVQAVVYGIVVYVMIG 461
            S F +   Q+  ++PY      +     Y  +G
Sbjct: 1268 SWFAFIAGQITSEIPYQVAVGTIAFFCWYYPLG 1300



 Score =  121 bits (304), Expect = 5e-27
 Identities = 139/566 (24%), Positives = 237/566 (41%), Gaps = 72/566 (12%)

Query: 37  LLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKTGGYIG--GNITISGY-PKKQETF 93
           +LK +    RPG LT ++G  GAG +TL+  ++    G +IG    IT  G  P   E  
Sbjct: 169 ILKSMDAIMRPGELTVVLGRPGAGCSTLLKTIAVNTYGFHIGKESQITYDGLSPHDIERH 228

Query: 94  ARISG-YCEQTDIHSPHVTVYESLLYSAWLRLSPD----INAETRKMFIEEV-MELVELK 147
            R    Y  +TD+H PH++V ++L ++A LR   +    I+ ET    +  V M    L 
Sbjct: 229 YRGDVIYSAETDVHFPHLSVGDTLEFAARLRTPQNRGEGIDRETYAKHMASVYMATYGLS 288

Query: 148 PLRYALVGLPGVSGLSTEQRKRLTVAVELVANPSIIFMDEPTSGLDARAAAIVMRAVR-N 206
             R   VG   V G+S  +RKR+++A   ++  +I   D  T GLD+  A   +RA++ +
Sbjct: 289 HTRNTNVGNDFVRGVSGGERKRVSIAEASLSGANIQCWDNATRGLDSATALEFIRALKTS 348

Query: 207 TVDTGRTVVCTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNSSNLINYFEGVQGVSK 266
            V    T +  I+Q S D ++ FD++++L +G Q I+ G     ++    YFE +    K
Sbjct: 349 AVILDTTPLIAIYQCSQDAYDLFDKVVVLYEGYQ-IFFG----KATKAKEYFEKMGW--K 401

Query: 267 IKDGYNPATWMLEVTTSSKEVEL--------------------RIDYAEVYKNSELY--- 303
                  A ++  +T  ++   L                      +YAE+ K  + Y   
Sbjct: 402 CPQRQTTADFLTSLTNPAEREPLPGYEDKVPRTAQEFETYWKNSPEYAELTKEIDEYFVE 461

Query: 304 --RRNKALIKELSAPAPCSKDLYFPSRYSRSFFTQCIACLWKQHWSYWRNPEYNAIRFLY 361
             R N       S  A  S +    S Y+ SFF Q    + +       +P         
Sbjct: 462 CERSNTRETYRESHVAKQSNNTRPASPYTVSFFMQVRYGVARNFLRMKGDPSIPIFSVFG 521

Query: 362 STAVAVLLGSMFWNLGSKIEKDQDLFNAMGSMYAAVILIGAMNSNSVQPVVGVERTVFYR 421
              + ++L S+F+NL     +    F   G+     +L  A +S      +   R +  +
Sbjct: 522 QLVMGLILSSVFYNL----SQTTGSFYYRGAAMFFAVLFNAFSSLLEIMSLFEARPIVEK 577

Query: 422 ERAARMYSAFPYALAQVVIQLPYVFVQAVVYGIVVYVMIGFE-------WTLVKVVWCLF 474
            +   +Y     ALA ++ +LP     ++ +  V Y M+ F        +  +  +WC F
Sbjct: 578 HKKYALYRPSADALASIISELPVKLAMSMSFNFVFYFMVNFRRNPGRFFFYWLMCIWCTF 637

Query: 475 FMYFTFLYF-TFYGMMSVAMTPNNHISIIVSSAFYSVWNLFSGFVLPRPGK**LISVILS 533
            M   F         +S AMTP        ++       +++GFV+P P          S
Sbjct: 638 VMSHLFRSIGAVSTSISGAMTP--------ATVLLLAMVIYTGFVIPTP----------S 679

Query: 534 IPVWWRWYSWANPVAWSLYGLVTSQY 559
           +  W RW ++ NPV +    L+ +++
Sbjct: 680 MLGWSRWINYINPVGYVFESLMVNEF 705


>PDRC_YEAST (Q02785) ATP-dependent permease PDR12
          Length = 1511

 Score =  238 bits (606), Expect = 5e-62
 Identities = 168/560 (30%), Positives = 282/560 (50%), Gaps = 31/560 (5%)

Query: 37   LLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKTGGYIGGNITISGYPKKQETFARI 96
            LL  + G  +PG +TALMG +GAGKTTL++VL+ R   G I G++ ++  P    +F R 
Sbjct: 860  LLSDVFGYVKPGKMTALMGESGAGKTTLLNVLAQRINMGVITGDMLVNAKPLPA-SFNRS 918

Query: 97   SGYCEQTDIHSPHVTVYESLLYSAWLRLSPDINAETRKMFIEEVMELVELKPLRYALVGL 156
             GY  Q D H   ++V ESL ++A LR    +  E +  ++E+++ L+ ++    ALVG 
Sbjct: 919  CGYVAQADNHMAELSVRESLRFAAELRQQSSVPLEEKYEYVEKIITLLGMQNYAEALVGK 978

Query: 157  PGVSGLSTEQRKRLTVAVELVANPSII-FMDEPTSGLDARAAAIVMRAVRNTVDTGRTVV 215
             G  GL+ EQRK+L++ VELVA PS++ F+DEPTSGLD+++A  +++ +R   D+G++++
Sbjct: 979  TG-RGLNVEQRKKLSIGVELVAKPSLLLFLDEPTSGLDSQSAWSIVQFMRALADSGQSIL 1037

Query: 216  CTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNSSNLINYFEGVQGVSKIKDGYNPAT 275
            CTIHQPS  +FE FD LLLLK+GG+ +Y G +G NS  L+ YFE   G+ K     NPA 
Sbjct: 1038 CTIHQPSATLFEQFDRLLLLKKGGKMVYFGDIGPNSETLLKYFERQSGM-KCGVSENPAE 1096

Query: 276  WMLEVTTSSKEVELRIDYAEVYKNSELYRRNKALIKELSAPAP---CSKDLYFPSRYSRS 332
            ++L    +     +  D+ +++  S      +A ++EL    P    + D    +R++ S
Sbjct: 1097 YILNCIGAGATASVNSDWHDLWLASPECAAARAEVEELHRTLPGRAVNDDPELATRFAAS 1156

Query: 333  FFTQCIACLWKQHWSYWRNPEYNAIRFLYSTAVAVLLGSMFWNLGSKIEKDQDLFNAMGS 392
            + TQ    L +    +WR+P Y   +F    A A+ +G  +  +   +    + F+++  
Sbjct: 1157 YMTQIKCVLRRTALQFWRSPVYIRAKFFECVACALFVGLSYVGVNHSVGGAIEAFSSI-- 1214

Query: 393  MYAAVILIGAMNSNSVQPVVGVERTVF-YRERAARMYSAFPYALAQVVIQLPYVFVQAVV 451
                ++LI     N +       R ++  RE A+  +      L    ++  +  +   +
Sbjct: 1215 --FMLLLIALAMINQLHVFAYDSRELYEVREAASNTFHWSVLLLCHAAVENFWSTLCQFM 1272

Query: 452  YGIVVYVMIGFEWTLVKVVWCLFFMYFTF-LYFTFYGMMSVAMTPNNHISIIVSSAFYSV 510
              I  Y    F        +  FF    F LYF  YG+  + M+P+   + +++S  ++ 
Sbjct: 1273 CFICYYWPAQFSGRASHAGFFFFFYVLIFPLYFVTYGLWILYMSPDVPSASMINSNLFAA 1332

Query: 511  WNLFSGFVLPRPGK**LISVILSIPVWWRWYSW-ANPVAWSLYGLVTSQYGDVK------ 563
              LF G + PR            +P +WR   +  +P  + +  LVT    + K      
Sbjct: 1333 MLLFCGILQPRE----------KMPAFWRRLMYNVSPFTYVVQALVTPLVHNKKVVCNPH 1382

Query: 564  -QNIETSDGRQTVEDFLRNY 582
              NI      +T  +FL  Y
Sbjct: 1383 EYNIMDPPSGKTCGEFLSTY 1402



 Score =  112 bits (280), Expect = 3e-24
 Identities = 121/567 (21%), Positives = 236/567 (41%), Gaps = 68/567 (11%)

Query: 37  LLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKTGGY-IGGNITISGYPKKQETFAR 95
           +++  +G    G +  ++G  GAG +T +  LSG  +    + G  +  G  +  E  ++
Sbjct: 163 IIQNCTGVVESGEMLFVVGRPGAGCSTFLKCLSGETSELVDVQGEFSYDGLDQS-EMMSK 221

Query: 96  ISGY---CEQTDIHSPHVTVYESLLYSAWLRLSPDINAE--TRKMFIEEVMEL----VEL 146
             GY   C + D H P +TV E++ ++   + +P +  +  TRK +++ + ++      L
Sbjct: 222 YKGYVIYCPELDFHFPKITVKETIDFALKCK-TPRVRIDKMTRKQYVDNIRDMWCTVFGL 280

Query: 147 KPLRYALVGLPGVSGLSTEQRKRLTVAVELVANPSIIFMDEPTSGLDARAAAIVMRAVRN 206
           +      VG   V G+S  +RKR+++      N SI   D  T GLDA  A    +A+R 
Sbjct: 281 RHTYATKVGNDFVRGVSGGERKRVSLVEAQAMNASIYSWDNATRGLDASTALEFAQAIRT 340

Query: 207 TVD-TGRTVVCTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNSSNLINYFEGVQGVS 265
             +    + +  I+Q   +I+E FD+  +L   G++IY GP    +   + YF+ +  V 
Sbjct: 341 ATNMVNNSAIVAIYQAGENIYELFDKTTVL-YNGRQIYFGP----ADKAVGYFQRMGWVK 395

Query: 266 KIKDGYNPATWMLEVTTSSKEVELRI-------------DYAEVYKNSELYRRNKALIKE 312
              +    A ++  VT   +   L I             ++ E + NSE Y+       +
Sbjct: 396 --PNRMTSAEFLTSVTVDFENRTLDIKPGYEDKVPKSSSEFEEYWLNSEDYQELLRTYDD 453

Query: 313 LSAPAPCS---------------KDLYFPSRYSRSFFTQCIACLWKQHWSYWRNPEYNAI 357
             +  P +               +     S+Y  +++TQ   C+ +       +  Y  +
Sbjct: 454 YQSRHPVNETRDRLDVAKKQRLQQGQRENSQYVVNYWTQVYYCMIRGFQRVKGDSTYTKV 513

Query: 358 RFLYSTAVAVLLGSMFWNLGSKIEKDQDLFNAMGSMYAAVILIGAMNSNSVQPVVGVERT 417
                   A+++GSMF  +  K +       + G M   V+L  ++ S +        R 
Sbjct: 514 YLSSFLIKALIIGSMFHKIDDKSQSTTAGAYSRGGMLFYVLLFASVTSLAEIGNSFSSRP 573

Query: 418 VFYRERAARMYSAFPYALAQVVIQLPYVFVQAVVYGIVVYVMIGFEWTLVKVVWCLFFMY 477
           V  + ++  MY     +L +++ + P  FV  V+  ++ Y +       +K     FF Y
Sbjct: 574 VIVKHKSYSMYHLSAESLQEIITEFPTKFVAIVILCLITYWI-----PFMKYEAGAFFQY 628

Query: 478 FTFLY-----FTFYGMMSVAMTPNNHISIIVSSAFYSVWNLFSGFVLPRPGK**LISVIL 532
             +L       +F       M+ +   +  V   +  +  +++GFVLP          I 
Sbjct: 629 ILYLLTVQQCTSFIFKFVATMSKSGVDAHAVGGLWVLMLCVYAGFVLP----------IG 678

Query: 533 SIPVWWRWYSWANPVAWSLYGLVTSQY 559
            +  W RW  + NP+ ++   LV++++
Sbjct: 679 EMHHWIRWLHFINPLTYAFESLVSTEF 705


>YN99_YEAST (P53756) Probable ATP-dependent transporter YNR070W
          Length = 1333

 Score =  237 bits (605), Expect = 6e-62
 Identities = 166/531 (31%), Positives = 278/531 (52%), Gaps = 36/531 (6%)

Query: 37   LLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKTGGYIGGNITISGYPKKQETFARI 96
            LL  +SG   PG LTAL+G +GAGKTTL++ L+ R  G  I G++ + G P    +F R 
Sbjct: 747  LLDSVSGYCVPGTLTALIGESGAGKTTLLNTLAQRNVGT-ITGDMLVDGLPM-DASFKRR 804

Query: 97   SGYCEQTDIHSPHVTVYESLLYSAWLRLSPDINAETRKMFIEEVMELVELKPLRYALVGL 156
            +GY +Q D+H   +TV ESL +SA +R    I    +  ++E+++ ++E++    ALVG 
Sbjct: 805  TGYVQQQDLHVAELTVKESLQFSARMRRPQSIPDAEKMEYVEKIISILEMQEFSEALVGE 864

Query: 157  PGVSGLSTEQRKRLTVAVELVANPSII-FMDEPTSGLDARAAAIVMRAVRNTVDTGRTVV 215
             G  GL+ EQRK+L++ VELV  P ++ F+DEPTSGLD+++A  V++ ++     G++++
Sbjct: 865  IGY-GLNVEQRKKLSIGVELVGKPDLLLFLDEPTSGLDSQSAWAVVKMLKRLALAGQSIL 923

Query: 216  CTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNSSNLINYFEGVQGVSKIKDGYNPAT 275
            CTIHQPS  +FE FD LLLL +GGQ IY G +G NSS++I YFE   G  K +   NPA 
Sbjct: 924  CTIHQPSATLFEQFDRLLLLGKGGQTIYFGEIGKNSSSVIKYFE-KNGARKCQQNENPAE 982

Query: 276  WMLEVTTSSKEVELRIDYAEVYKNSELY----RRNKALIKELSAPAPCSKDLYFPSRYSR 331
            ++LE   +     ++ ++ ++++ S  Y     +   +IK+LS+     K     S+Y+ 
Sbjct: 983  YILEAIGAGATASVQQNWPDIWQKSHEYANINEKINDMIKDLSS-TTLHKTATRASKYAT 1041

Query: 332  SFFTQCIACLWKQHWSYWRNPEYNAIRFLYSTAVAVLLGSMFWNLGSKIEKDQDLFNAMG 391
            S+  Q    L +   ++WRN  Y   + +      + +G  F+++G          NA+G
Sbjct: 1042 SYSYQFHHVLKRSSLTFWRNLNYIMAKMMLLMISGLFIGFTFFHVG---------VNAIG 1092

Query: 392  ---SMYAA--VILIGAMNSNSVQPVVGVERTVF-YRERAARMYSAFPYALAQVVIQLPYV 445
               S++A    I+I A  +N +Q    V + ++  RE  + M+      +   + +LPY 
Sbjct: 1093 LQNSLFACFMAIVISAPATNQIQERATVAKELYEVRESKSNMFHWSLLLITHYLNELPYH 1152

Query: 446  FVQAVVYGIVVYVMIG-FEWTLVKVVWCLFFMYFTFLYFTFYGMMSVAMTPNNHISIIVS 504
             + + ++ +  Y  +G F       V+ L +     LY+    +M + M+PN   + ++ 
Sbjct: 1153 LLFSTIFFVSSYFPLGVFTEASRSSVFYLNYAILFQLYYIGLALMILYMSPNLQSANVIV 1212

Query: 505  SAFYSVWNLFSGFVLPRPGK**LISVILSIPVWWRWYSWANPVAWSLYGLV 555
                S    F G V P             +P +W +    +P  + L  LV
Sbjct: 1213 GFILSFLLSFCGAVQPAS----------LMPGFWTFMWKLSPYTYFLQNLV 1253



 Score =  114 bits (284), Expect = 1e-24
 Identities = 126/578 (21%), Positives = 244/578 (41%), Gaps = 71/578 (12%)

Query: 23  QEMRNRGVIEDKLVLLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKT---GGYIGG 79
           +E +NR  ++   ++LK +S   + G +  ++G  GAG T+ +   +G  +   GG   G
Sbjct: 34  RERKNRNKMK---IILKNVSLLAKSGEMVLVLGRPGAGCTSFLKSAAGETSQFAGGVTTG 90

Query: 80  NITISGYPKKQ--ETFARISGYCEQTDIHSPHVTVYESLLYSAWLRL-SPDINAETRKMF 136
           +I+  G P+K+  + +     Y  + D+H PH+TV ++L ++   ++ +  +N  T++ +
Sbjct: 91  HISYDGIPQKEMMQHYKPDVIYNGEQDVHFPHLTVKQTLDFAISCKMPAKRVNNVTKEEY 150

Query: 137 I----EEVMELVELKPLRYALVGLPGVSGLSTEQRKRLTVAVELVANPSIIFMDEPTSGL 192
           I    E   ++  L       VG   +SG+S  +RKR+++A  L A  SI   D  T GL
Sbjct: 151 ITANREFYAKIFGLTHTFDTKVGNDFISGVSGGERKRVSIAEALAAKGSIYCWDNATRGL 210

Query: 193 DARAAAIVMRAVRNTVD-TGRTVVCTIHQPSIDIFESFDELLLLKQGGQEI--------- 242
           D+  A    RA+R   +  G T + T++Q S +I+E+FD++ +L  G Q           
Sbjct: 211 DSSTALEFARAIRTMTNLLGTTALVTVYQASENIYETFDKVTVLYAGRQIFCGKTTEAKD 270

Query: 243 ------YVGPLGHNSSNLINYFEGVQGVSKIKDGY-----NPATWMLEVTTSSKEVELRI 291
                 Y+ P   +++  +       G+ +IK G+     + A    +    S E     
Sbjct: 271 YFENMGYLCPPRQSTAEYLTAITDPNGLHEIKPGFEYQVPHTADEFEKYWLDSPEYARLK 330

Query: 292 DYAEVYKNSELYRRNKALIKELSAPAPCSKDLYFPSRYSRSFFTQCIACLWKQHWSYWRN 351
              + YK+       K    E  A    SK     S Y+ S++ Q   C  +     + +
Sbjct: 331 GEIQKYKHEVNTEWTKKTYNESMAQEK-SKGTRKKSYYTVSYWEQIRLCTIRGFLRIYGD 389

Query: 352 PEYNAIRFLYSTAVAVLLGSMFWNLGSKIEKDQDLFNAMGSMYAAVILIGAMNSNSVQPV 411
             Y  I    + A A + GS+F+   S        F+  G ++ +++    M   ++   
Sbjct: 390 KSYTVINTCAAIAQAFITGSLFYQAPS---STLGAFSRSGVLFFSLLYYSLMGLANIS-- 444

Query: 412 VGVERTVFYRERAARMYSAFPYALAQVVIQLPYVFVQAVVYGIVVYVMIGFEWTLVKVVW 471
               R +  + +   +Y     ALA  +   P+  +    + I++Y + G    L +   
Sbjct: 445 -FEHRPILQKHKVYSLYHPSAEALASTISSFPFRMIGLTFFIIILYFLAG----LHRSAG 499

Query: 472 CLFFMYFTFL--------YFTFYGMMSVAMTPNNHIS--IIVSSAFYSVWNLFSGFVLPR 521
             F MY             F     +   ++  N I+  +++S A YS + +     LP 
Sbjct: 500 AFFTMYLLLTMCSEAITSLFQMVSSLCDTLSQANSIAGVVMLSIAMYSTYMI----QLP- 554

Query: 522 PGK**LISVILSIPVWWRWYSWANPVAWSLYGLVTSQY 559
                      S+  W++W S+  P+ ++   ++ +++
Sbjct: 555 -----------SMHPWFKWISYILPIRYAFESMLNAEF 581


>CDR4_CANAL (O74676) ABC transporter CDR4
          Length = 1490

 Score =  236 bits (602), Expect = 1e-61
 Identities = 153/462 (33%), Positives = 240/462 (51%), Gaps = 13/462 (2%)

Query: 32   EDKLVLLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKTGGYIGGNITISGYPKKQE 91
            ED+ V+L  +SG  +PG +TALMG +GAGKTTL++ LS R T G +   I +        
Sbjct: 860  EDR-VILDHVSGWVKPGQVTALMGASGAGKTTLLNALSDRLTTGVVTEGIRLVNGRPLDS 918

Query: 92   TFARISGYCEQTDIHSPHVTVYESLLYSAWLRLSPDINAETRKMFIEEVMELVELKPLRY 151
            +F R  GY +Q D+H    TV E+L ++A+LR    ++ + +  +++ ++ L+E++    
Sbjct: 919  SFQRSIGYVQQQDLHLETSTVREALEFAAYLRQPKSVSRKEKNEYVDYIIRLLEMEQYAD 978

Query: 152  ALVGLPGVSGLSTEQRKRLTVAVELVANPSI-IFMDEPTSGLDARAAAIVMRAVRNTVDT 210
            A+VG+ G  GL+ EQRKRL++ VELVA P + +F+DEPTSGLD++ A  + + +R   D 
Sbjct: 979  AVVGVSG-EGLNVEQRKRLSIGVELVAKPKLLVFLDEPTSGLDSQTAWSICKLIRKLADN 1037

Query: 211  GRTVVCTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNSSNLINYFEGVQGVSKIKDG 270
            G+ ++CTIHQPS  +   FD LL L++GGQ +Y G LG N + LINYFE   G  K    
Sbjct: 1038 GQAILCTIHQPSAILLAEFDRLLFLQRGGQTVYFGDLGKNFTTLINYFE-KYGAPKCPPE 1096

Query: 271  YNPATWMLEVTTSSKEVELRIDYAEVY-KNSELYRRNKA--LIKELSAPAPCSKDLYFPS 327
             NPA WMLEV  ++   +   DY +V+ K+SE    N    L+ E     P   D     
Sbjct: 1097 ANPAEWMLEVIGAAPGSKANQDYYDVWLKSSEFQEMNSELDLMSEELVKKPLDDDPDRLK 1156

Query: 328  RYSRSFFTQCIACLWKQHWSYWRNPEYNAIRFLYSTAVAVLLGSMFWNLGSKIEKDQDLF 387
             Y+  ++ Q +    +     WR P Y   +FL     ++  G  F+     +   Q L 
Sbjct: 1157 PYAAPYWEQYLFVTKRVFEQNWRTPSYLYSKFLLVVTSSLFNGFSFYKADRSL---QGLQ 1213

Query: 388  NAMGSMYAAVILIGAMNSNSVQPVVGVERTVFYRERAARMYSAFPYALAQVVIQLPYVFV 447
            N M S++  ++++  +    +   V        RER ++ +S   +  AQV  ++P+  +
Sbjct: 1214 NQMFSVFMFLVILHTLIQQYLPTFVSQRDLYEVRERPSKTFSWITFIAAQVTAEIPWNII 1273

Query: 448  QAVVYGIVVYVMIGF--EWTLVKVVWCL-FFMYFTFLYFTFY 486
               +     Y  +G     T    V     FM+F  + F  Y
Sbjct: 1274 CGTLGYFCWYYPVGLYQNATYTNTVHQRGAFMWFAIVLFFIY 1315



 Score =  119 bits (299), Expect = 2e-26
 Identities = 129/554 (23%), Positives = 241/554 (43%), Gaps = 48/554 (8%)

Query: 37  LLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKTGGYIGGNITI-----SGYPKKQE 91
           +LK + G  +PG LT ++G  GAG +T +  ++ +  G +I  +  I     + +  K+ 
Sbjct: 172 ILKPMDGLIKPGELTVVLGRPGAGCSTFLKTIASQTYGYHIDKDSVIRYNSLTPHEIKKH 231

Query: 92  TFARISGYCEQTDIHSPHVTVYESLLYSAWLR------LSPDINAETRKMFIEEVMELVE 145
               +  YC +T+ H P +TV ++L ++A +R      L    +A  R +    VM +  
Sbjct: 232 YRGEVV-YCAETENHFPQLTVGDTLEFAAKMRTPQNRPLGVSRDAYARHL-AAVVMAVYG 289

Query: 146 LKPLRYALVGLPGVSGLSTEQRKRLTVAVELVANPSIIFMDEPTSGLDARAAAIVMRAVR 205
           L   R   VG   + G+S  +RKR+++A   + N  +   D  T GLD+  A   +RA++
Sbjct: 290 LSHTRNTKVGNDFIRGVSGGERKRVSIAEITLNNAMVQCWDNSTRGLDSATALEFIRALK 349

Query: 206 NTVDTGRTV-VCTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNSSNLINY-FEGVQG 263
            + D   T  +  I+Q S D ++ FD+++L+ QG Q IY G         I+  +E  Q 
Sbjct: 350 ASADIVHTTPLVAIYQCSQDAYDLFDKVVLMYQGYQ-IYFGSAKKAKQYFIDMGYECPQR 408

Query: 264 VSK---IKDGYNPATWMLEVTTSSKEVELRIDYAEVYKNSE------------LYRRNKA 308
            +    +    NPA  ++      K  +   ++ E +K S             L   + A
Sbjct: 409 QTTADFLTSLTNPAERIVRQGFEGKVPQTPQEFYEYWKKSPEGQQIVADVDQYLTEHSSA 468

Query: 309 LIKEL---SAPAPCSKDLYFPSRYSRSFFTQCIACLWKQHWSYWRNPEYNAIRFLYSTAV 365
             KE    +  A  S  L   S Y+ SFF Q      +       NP  +  +   +  +
Sbjct: 469 AEKEAIKEAHQARQSDHLKPASPYTVSFFMQVRYIAHRNILRIKGNPSIHLFQIFGNIGM 528

Query: 366 AVLLGSMFWNLGSKIEKDQDLFNAMGSMYAAVILIGAMNSNSVQPVVGVERTVFYRERAA 425
           + +L S+F+NL +        ++   +++ AV L  A +       +   R++  + +  
Sbjct: 529 SFILSSIFYNLPT---ATSSFYHRTAALFFAV-LFNAFSCLLEIFSLYEARSIVEKHKKY 584

Query: 426 RMYSAFPYALAQVVIQLPYVFVQAVVYGIVVYVMIGFEWTLVKVVWCLFFMYFTFLYFTF 485
            +Y     A A +V +LP  F+ A+ + +V Y M+ F  T     + L   +   L  + 
Sbjct: 585 ALYHPAADAFASIVTELPTKFIIAIGFNLVYYFMVNFRRTPGNFFFYLLINFSATLAMSH 644

Query: 486 YGMMSVAMTPNNHISIIVSSAFYSVWNLFSGFVLPRPGK**LISVILSIPVWWRWYSWAN 545
                 A T     ++  ++       +F+GFV+P P          ++  W RW ++ +
Sbjct: 645 IFRTIGAATKTLQEAMTPAAILLLALTIFTGFVIPTP----------NMHGWCRWINYLD 694

Query: 546 PVAWSLYGLVTSQY 559
           P+A++   L+ +++
Sbjct: 695 PLAYAFESLIANEF 708


>ABG4_HUMAN (Q9H172) ATP-binding cassette, sub-family G, member 4
          Length = 646

 Score =  214 bits (545), Expect = 5e-55
 Identities = 167/556 (30%), Positives = 267/556 (47%), Gaps = 37/556 (6%)

Query: 10  ITFDEVSYSVDMPQEMRNRGVIEDKLVLLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLS 69
           I F E+SYSV      R RG       LLK LSG F    L  +MG +GAGK+T M++L+
Sbjct: 61  IEFVELSYSVREGPCWRKRGY----KTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILA 116

Query: 70  GRKTGGYIGGNITISGYPKKQETFARISGYCEQTDIHSPHVTVYESLLYSAWLRLSPDIN 129
           G +  G + G I ++G P++  TF ++S Y  Q D+  PH+TV E+++ SA L+LS    
Sbjct: 117 GYRESG-MKGQILVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSE--K 173

Query: 130 AETRKMFIEEVMELVELKPLRYALVGLPGVSGLSTEQRKRLTVAVELVANPSIIFMDEPT 189
            E +K  + E++  + L    +    L     LS  QRKRL +A+ELV NP ++F DEPT
Sbjct: 174 QEVKKELVTEILTALGLMSCSHTRTAL-----LSGGQRKRLAIALELVNNPPVMFFDEPT 228

Query: 190 SGLDARAAAIVMRAVRNTVDTGRTVVCTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGH 249
           SGLD+ +   V+  +++    GRT++CTIHQPS  +FE FD+L +L Q GQ I+ G +  
Sbjct: 229 SGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQ-GQCIFKGVV-- 285

Query: 250 NSSNLINYFEGVQGVSKIKDGYNPATWMLEVTTSSKEVELRIDYAEVYKNSELYRRNKAL 309
             +NLI Y +G+         +NPA +++EV +        + +  V          K+ 
Sbjct: 286 --TNLIPYLKGLG--LHCPTYHNPADFIIEVASGEYGDLNPMLFRAVQNGLCAMAEKKSS 341

Query: 310 IKELSAPAPC-----SKDLYFPSRYSRSFFTQCIACLWKQHWSYWRNPEYNAIRFLYSTA 364
            ++   PAPC       D      ++ S  TQ      +   S  R+     +RF+    
Sbjct: 342 PEKNEVPAPCPPCPPEVDPIESHTFATSTLTQFCILFKRTFLSILRDTVLTHLRFMSHVV 401

Query: 365 VAVLLGSMFWNLGSKIEKDQDLFNAMGSMYAAVILIGAMNSNSVQPVVGVERTVFYRERA 424
           + VL+G ++ ++G    K   +FN  G ++ +++ +             +E  VF RE  
Sbjct: 402 IGVLIGLLYLHIGDDASK---VFNNTGCLFFSMLFLMFAALMPTVLTFPLEMAVFMREHL 458

Query: 425 ARMYSAFPYALAQVVIQLPYVFVQAVVYGIVVYVMIGFEWTLVKVVWCLFFMYFTFLYFT 484
              YS   Y LA+ +  +P+  V  VVY  +VY M G      + +        T L   
Sbjct: 459 NYWYSLKAYYLAKTMADVPFQVVCPVVYCSIVYWMTGQPAETSRFLLFSALATATALVAQ 518

Query: 485 FYGMMSVAMTPNNHISIIVSSAFYSVWNLFSGFVLPRPGK**LISVILSIPVWWRWYSWA 544
             G++  A + +  ++  V         LFSGF +             +IP + +W S+ 
Sbjct: 519 SLGLLIGAASNSLQVATFVGPVTAIPVLLFSGFFVS----------FKTIPTYLQWSSYL 568

Query: 545 NPVAWSLYGLVTSQYG 560
           + V +   G++ + YG
Sbjct: 569 SYVRYGFEGVILTIYG 584


>WHIT_DROME (P10090) White protein
          Length = 687

 Score =  208 bits (530), Expect = 3e-53
 Identities = 150/536 (27%), Positives = 267/536 (48%), Gaps = 30/536 (5%)

Query: 37  LLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKTGGYI---GGNITISGYPKKQETF 93
           LLK + G   PG L A+MG +GAGKTTL++ L+ R   G      G   ++G P   +  
Sbjct: 112 LLKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFRSPQGIQVSPSGMRLLNGQPVDAKEM 171

Query: 94  ARISGYCEQTDIHSPHVTVYESLLYSAWLRLSPDINAETRKMFIEEVMELVELKPLRYAL 153
                Y +Q D+    +T  E L++ A +R+   +    R   +++V++ + L   ++ +
Sbjct: 172 QARCAYVQQDDLFIGSLTAREHLIFQAMVRMPRHLTYRQRVARVDQVIQELSLSKCQHTI 231

Query: 154 VGLPG-VSGLSTEQRKRLTVAVELVANPSIIFMDEPTSGLDARAAAIVMRAVRNTVDTGR 212
           +G+PG V GLS  +RKRL  A E + +P ++  DEPTSGLD+  A  V++ ++     G+
Sbjct: 232 IGVPGRVKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFTAHSVVQVLKKLSQKGK 291

Query: 213 TVVCTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNSSNLINYFEGVQGVSKIKDGYN 272
           TV+ TIHQPS ++FE FD++LL+ + G+  ++G      S  +++F  V   ++    YN
Sbjct: 292 TVILTIHQPSSELFELFDKILLMAE-GRVAFLG----TPSEAVDFFSYVG--AQCPTNYN 344

Query: 273 PATWMLEV--TTSSKEVELRIDYAEVYKNSELYRRNKALIKELSAPAPCSKDLYFPSR-- 328
           PA + ++V      +E+E R   A++  N  + +  + + ++L A     K L  P    
Sbjct: 345 PADFYVQVLAVVPGREIESRDRIAKICDNFAISKVARDM-EQLLATKNLEKPLEQPENGY 403

Query: 329 -YSRSFFTQCIACLWKQHWSYWRNPEYNAIRFLYSTAVAVLLGSMFWNLGSKIEKDQDLF 387
            Y  ++F Q  A LW+   S  + P    +R + +T VA+L+G +F  LG ++ +   + 
Sbjct: 404 TYKATWFMQFRAVLWRSWLSVLKEPLLVKVRLIQTTMVAILIGLIF--LGQQLTQ-VGVM 460

Query: 388 NAMGSMYAAVILIGAMNSNSVQPVVGVERTVFYRERAARMYSAFPYALAQVVIQLPYVFV 447
           N  G+++  +  +   N  +   V   E  VF RE  +R+Y    Y L + + +LP    
Sbjct: 461 NINGAIFLFLTNMTFQNVFATINVFTSELPVFMREARSRLYRCDTYFLGKTIAELPLFLT 520

Query: 448 QAVVYGIVVYVMIGFEWTLVKVVWCLFFMYFTFLYFTFYGMMSVAMTPNNHISIIVSSAF 507
             +V+  + Y MIG    ++    CL  +       T +G +    + +  +++ V    
Sbjct: 521 VPLVFTAIAYPMIGLRAGVLHFFNCLALVTLVANVSTSFGYLISCASSSTSMALSVGPPV 580

Query: 508 YSVWNLFSGFVLPRPGK**LISVILSIPVWWRWYSWANPVAWSLYGLVTSQYGDVK 563
              + LF GF L             S+PV+ +W S+ +   ++  GL+ +Q+ DV+
Sbjct: 581 IIPFLLFGGFFLNSG----------SVPVYLKWLSYLSWFRYANEGLLINQWADVE 626


>ABG1_MOUSE (Q64343) ATP-binding cassette, sub-family G, member 1
           (White protein homolog) (ATP-binding cassette
           transporter 8)
          Length = 666

 Score =  205 bits (521), Expect = 3e-52
 Identities = 168/575 (29%), Positives = 277/575 (47%), Gaps = 70/575 (12%)

Query: 9   SITFDEVSYSVDMPQEMRNRGVIEDKLVLLKGLSGAFRPGVLTALMGVTGAGKTTLMDVL 68
           +I F ++SYSV      + +G       LLKG+SG F  G L A+MG +GAGK+TLM++L
Sbjct: 76  NIEFKDLSYSVPEGPWWKKKGY----KTLLKGISGKFNSGELVAIMGPSGAGKSTLMNIL 131

Query: 69  SG-RKTGGYIGGNITISGYPKKQETFARISGYCEQTDIHSPHVTVYESLLYSAWLRLSPD 127
           +G R+TG  + G + I+G P+    F ++S Y  Q D+  PH+TV E+++ SA L+L   
Sbjct: 132 AGYRETG--MKGAVLINGMPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQE- 188

Query: 128 INAETRKMFIEEVMELVELKPLRYALVGLPGVSGLSTEQRKRLTVAVELVANPSIIFMDE 187
              E R+  ++E++  + L P      G      LS  QRKRL +A+ELV NP ++F DE
Sbjct: 189 -KDEGRREMVKEILTALGLLPCANTRTG-----SLSGGQRKRLAIALELVNNPPVMFFDE 242

Query: 188 PTSGLDARAAAIVMRAVRNTVDTGRTVVCTIHQPSIDIFESFDELLLLKQGGQEIYVGPL 247
           PTSGLD+ +   V+  ++     GR++VCTIHQPS  +FE FD+L +L Q GQ +Y G +
Sbjct: 243 PTSGLDSASCFQVVSLMKGLAQGGRSIVCTIHQPSAKLFELFDQLYVLSQ-GQCVYRGKV 301

Query: 248 GHNSSNLINYFEGVQGVSKIKDGYNPATWMLEVTTSSKEVELRIDYAEVYKNSELYRRNK 307
               SNL+ Y   + G++     +NPA +++EV +         +Y +  +NS L R   
Sbjct: 302 ----SNLVPYLRDL-GLN-CPTYHNPADFVMEVASG--------EYGD--QNSRLVR--- 342

Query: 308 ALIKELSAPAPCSKDL-----------YFPSR-----------YSRSFFTQCIACLWKQH 345
             ++E    A   +DL           + P+            +S S  TQ      +  
Sbjct: 343 -AVREGMCDADYKRDLGGDTDVNPFLWHRPAEEDSASMEGCHSFSASCLTQFCILFKRTF 401

Query: 346 WSYWRNPEYNAIRFLYSTAVAVLLGSMFWNLGSKIEKDQDLFNAMGSMYAAVILIGAMNS 405
            S  R+     +R      + +L+G ++  +G++ +K   + +  G ++ +++ +     
Sbjct: 402 LSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKK---VLSNSGFLFFSMLFLMFAAL 458

Query: 406 NSVQPVVGVERTVFYRERAARMYSAFPYALAQVVIQLPYVFVQAVVYGIVVYVMIGFEWT 465
                   +E +VF RE     YS   Y LA+ +  +P+  +  V Y  +VY M      
Sbjct: 459 MPTVLTFPLEMSVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSD 518

Query: 466 LVKVVWCLFFMYFTFLYFTFYGMMSVAMTPNNHISIIVSSAFYSVWNLFSGFVLPRPGK* 525
            V+ V        T L     G++  A + +  ++  V         LFSGF +      
Sbjct: 519 AVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVS----- 573

Query: 526 *LISVILSIPVWWRWYSWANPVAWSLYGLVTSQYG 560
                  +IP + +W S+ + V +   G++ S YG
Sbjct: 574 -----FDTIPAYLQWMSYISYVRYGFEGVILSIYG 603


>WHIT_CERCA (Q17320) White protein
          Length = 679

 Score =  202 bits (513), Expect = 3e-51
 Identities = 159/578 (27%), Positives = 276/578 (47%), Gaps = 38/578 (6%)

Query: 37  LLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKTGGYIGGNITI---SGYPKKQETF 93
           LLK  SG   PG L A+MG +GAGKTTL++  + R + G      TI   +G+P   +  
Sbjct: 103 LLKNDSGVAYPGELLAVMGSSGAGKTTLLNASAFRSSKGVQISPSTIRMLNGHPVDAKEM 162

Query: 94  ARISGYCEQTDIHSPHVTVYESLLYSAWLRLSPDINAETRKMFIEEVMELVELKPLRYAL 153
                Y +Q D+    +T  E L++ A +R+   +  + +   +++V++ + L   +  L
Sbjct: 163 QARCAYVQQDDLFIGSLTAREHLIFQAMVRMPRHMTQKQKVQRVDQVIQDLSLGKCQNTL 222

Query: 154 VGLPG-VSGLSTEQRKRLTVAVELVANPSIIFMDEPTSGLDARAAAIVMRAVRNTVDTGR 212
           +G+PG V GLS  +RKRL  A E + +P ++  DEPTSGLD+  A  V++ ++     G+
Sbjct: 223 IGVPGRVKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFMAHSVVQVLKKLSQKGK 282

Query: 213 TVVCTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNSSNLINYFEGVQGVSKIKDGYN 272
           TV+ TIHQPS ++FE FD++LL+ + G+  ++G  G      +++F  +   +     Y 
Sbjct: 283 TVILTIHQPSSELFELFDKILLMAE-GRVAFLGTPG----EAVDFFSYIG--ATCPTNYT 335

Query: 273 PATWMLEV--TTSSKEVELRIDYAEVYKN---SELYRRNKALIKELSAPAPCSKDLYFPS 327
           PA + ++V      +EVE R   A++  N    ++ R  +   ++L       K+     
Sbjct: 336 PADFYVQVLAVVPGREVESRDRVAKICDNFAVGKVSREMEQNFQKLVKSNGFGKEDENEY 395

Query: 328 RYSRSFFTQCIACLWKQHWSYWRNPEYNAIRFLYSTAVAVLLGSMFWNLGSKIEKDQDLF 387
            Y  S+F Q  A LW+   S  + P    +R L +T VAVL+G +F  LG ++ +   + 
Sbjct: 396 TYKASWFMQFRAVLWRSWLSVLKEPLLVKVRLLQTTMVAVLIGLIF--LGQQLTQ-VGVM 452

Query: 388 NAMGSMYAAVILIGAMNSNSVQPVVGVERTVFYRERAARMYSAFPYALAQVVIQLPYVFV 447
           N  G+++  +  +   NS +   V   E  VF RE  +R+Y    Y L + + +LP   V
Sbjct: 453 NINGAIFLFLTNMTFQNSFATITVFTTELPVFMRETRSRLYRCDTYFLGKTIAELPLFLV 512

Query: 448 QAVVYGIVVYVMIGFEWTLVKVVWCLFFMYFTFLYFTFYGMMSVAMTPNNHISIIVSSAF 507
              ++  + Y +IG    +      L  +       T +G +      +  +++ V    
Sbjct: 513 VPFLFTAIAYPLIGLRPGVDHFFTALALVTLVANVSTSFGYLISCACSSTSMALSVGPPV 572

Query: 508 YSVWNLFSGFVLPRPGK**LISVILSIPVWWRWYSWANPVAWSLYGLVTSQYGDVKQNIE 567
              + LF GF L             S+PV+++W S+ +   ++  GL+ +Q+ DVK    
Sbjct: 573 IIPFLLFGGFFLNSG----------SVPVYFKWLSYLSWFRYANEGLLINQWADVKPGEI 622

Query: 568 T---------SDGRQTVEDFLRNYFGFKHDFLGVVALV 596
           T         S G   +E    +      DF+G+  L+
Sbjct: 623 TCTLSNTTCPSSGEVILETLNFSASDLPFDFIGLALLI 660


>ABG1_HUMAN (P45844) ATP-binding cassette, sub-family G, member 1
           (White protein homolog) (ATP-binding cassette
           transporter 8)
          Length = 678

 Score =  199 bits (505), Expect = 2e-50
 Identities = 178/602 (29%), Positives = 287/602 (47%), Gaps = 68/602 (11%)

Query: 9   SITFDEVSYSVDMPQEMRNRGVIEDKLVLLKGLSGAFRPGVLTALMGVTGAGKTTLMDVL 68
           +I F ++SYSV      R +G       LLKG+SG F  G L A+MG +GAGK+TLM++L
Sbjct: 76  NIEFRDLSYSVPEGPWWRKKGY----KTLLKGISGKFNSGELVAIMGPSGAGKSTLMNIL 131

Query: 69  SG-RKTGGYIGGNITISGYPKKQETFARISGYCEQTDIHSPHVTVYESLLYSAWLRLSPD 127
           +G R+TG  + G + I+G P+    F ++S Y  Q D+  PH+TV E+++ SA L+L   
Sbjct: 132 AGYRETG--MKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQE- 188

Query: 128 INAETRKMFIEEVMELVELKPLRYALVGLPGVSGLSTEQRKRLTVAVELVANPSIIFMDE 187
              E R+  ++E++  + L        G      LS  QRKRL +A+ELV NP ++F DE
Sbjct: 189 -KDEGRREMVKEILTALGLLSCANTRTG-----SLSGGQRKRLAIALELVNNPPVMFFDE 242

Query: 188 PTSGLDARAAAIVMRAVRNTVDTGRTVVCTIHQPSIDIFESFDELLLLKQGGQEIYVGPL 247
           PTSGLD+ +   V+  ++     GR+++CTIHQPS  +FE FD+L +L QG Q +Y G +
Sbjct: 243 PTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQG-QCVYRGKV 301

Query: 248 GHNSSNLINYFEGVQGVSKIKDGYNPATWMLEVTTSS------------KEVELRIDY-- 293
                NL+ Y   + G++     +NPA +++EV +              +E     D+  
Sbjct: 302 ----CNLVPYLRDL-GLN-CPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKR 355

Query: 294 -----AEVYKNSELYRRNKALIKELSAPAPCSKD---LYFPSRYSRSFFTQCIACLWKQH 345
                AEV  N  L+ R    +K+        KD   +     +S S  TQ      +  
Sbjct: 356 DLGGDAEV--NPFLWHRPSEEVKQTKRLKGLRKDSSSMEGCHSFSASCLTQFCILFKRTF 413

Query: 346 WSYWRNPEYNAIRFLYSTAVAVLLGSMFWNLGSKIEKDQDLFNAMGSMYAAVILIGAMNS 405
            S  R+     +R      + +L+G ++  +G++ +K   L N+    ++ + L+ A   
Sbjct: 414 LSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKV--LSNSGFLFFSMLFLMFA--- 468

Query: 406 NSVQPVV---GVERTVFYRERAARMYSAFPYALAQVVIQLPYVFVQAVVYGIVVYVMIGF 462
            ++ P V    +E  VF RE     YS   Y LA+ +  +P+  +  V Y  +VY M   
Sbjct: 469 -ALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQ 527

Query: 463 EWTLVKVVWCLFFMYFTFLYFTFYGMMSVAMTPNNHISIIVSSAFYSVWNLFSGFVLPRP 522
               V+ V        T L     G++  A + +  ++  V         LFSGF +   
Sbjct: 528 PSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVS-- 585

Query: 523 GK**LISVILSIPVWWRWYSWANPVAWSLYGLVTSQYG----DVKQNIETSDGRQTVEDF 578
                     +IP + +W S+ + V +   G++ S YG    D+  +I+ +   Q  E  
Sbjct: 586 --------FDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIDETCHFQKSEAI 637

Query: 579 LR 580
           LR
Sbjct: 638 LR 639


>WHIT_LUCCU (Q05360) White protein
          Length = 677

 Score =  197 bits (501), Expect = 7e-50
 Identities = 157/598 (26%), Positives = 287/598 (47%), Gaps = 47/598 (7%)

Query: 37  LLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKTGGYIGGNITI---SGYPKKQETF 93
           L+K + G   PG L A+MG +GAGKTTL++ L+ R   G      ++   +G+P   +  
Sbjct: 101 LIKNVCGVAYPGELLAVMGSSGAGKTTLLNALAFRSARGVQISPSSVRMLNGHPVDAKEM 160

Query: 94  ARISGYCEQTDIHSPHVTVYESLLYSAWLRLSPDINAETRKMFIEEVMELVELKPLRYAL 153
                Y +Q D+    +T  E L++ A +R+   +  + +   +++V++ + L   +  +
Sbjct: 161 QARCAYVQQDDLFIGSLTAREHLIFQATVRMPRTMTQKQKLQRVDQVIQDLSLIKCQNTI 220

Query: 154 VGLPG-VSGLSTEQRKRLTVAVELVANPSIIFMDEPTSGLDARAAAIVMRAVRNTVDTGR 212
           +G+PG V GLS  +RKRL  A E + +P ++  DEPTSGLD+  AA V++ ++     G+
Sbjct: 221 IGVPGRVKGLSGGERKRLAFASEALTDPPLLICDEPTSGLDSFMAASVVQVLKKLSQRGK 280

Query: 213 TVVCTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNSSNLINYFEGVQGVSKIKDGYN 272
           TV+ TIHQPS ++FE FD++LL+ +G       P+       +++F  +   ++    YN
Sbjct: 281 TVILTIHQPSSELFELFDKILLMAEGRVAFLGTPV-----EAVDFFSFIG--AQCPTNYN 333

Query: 273 PATWMLEV--TTSSKEVELRIDYAEVYKN---SELYRRNKALIKELSAPAP-CSKDLYFP 326
           PA + ++V      +E+E R   +++  N    ++ R  +   ++++A      KD    
Sbjct: 334 PADFYVQVLAVVPGREIESRDRISKICDNFAVGKVSREMEQNFQKIAAKTDGLQKDDETT 393

Query: 327 SRYSRSFFTQCIACLWKQHWSYWRNPEYNAIRFLYSTAVAVLLGSMFWNLGSKIEKDQDL 386
             Y  S+FTQ  A +W+   S  + P    +R + +T VAVL+G +F N   +      +
Sbjct: 394 ILYKASWFTQFRAIMWRSWISTLKEPLLVKVRLIQTTMVAVLIGLIFLN---QPMTQVGV 450

Query: 387 FNAMGSMYAAVILIGAMNSNSVQPVVGVERTVFYRERAARMYSAFPYALAQVVIQLPYVF 446
            N  G+++  +  +   N  +V  V   E  VF RE  +R+Y    Y L + + +LP   
Sbjct: 451 MNINGAIFLFLTNMTFQNVFAVINVFTSELPVFMRETRSRLYRCDTYFLGKTLAELPLFL 510

Query: 447 VQAVVYGIVVYVMIGFEWTLVKVVWCLFFMYFTFLYFTFYGMMSVAMTPNNHISIIVSSA 506
           V   ++  + Y MIG    +   +  L  +       T +G +    + +  +++ V   
Sbjct: 511 VVPFLFIAIAYPMIGLRPGITHFLSALALVTLVANVSTSFGYLISCASTSTSMALSVGPP 570

Query: 507 FYSVWNLFSGFVLPRPGK**LISVILSIPVWWRWYSWANPVAWSLYGLVTSQYGDVKQNI 566
               + LF G  L             S+PV+++W S+ +   ++  GL+ +Q+ DV+   
Sbjct: 571 LTIPFLLFGGVFLNSG----------SVPVYFKWLSYFSWFRYANEGLLINQWADVQPGE 620

Query: 567 ET---------SDGRQTVEDF-LRNYFGFKHDFLGVVALVNIAFPIVFALVFAIAIKM 614
            T         S G   +E    R+ F F+    G++ L+     ++F +   +A KM
Sbjct: 621 ITCTSTNTTCPSSGXVXLETLNFRDKFTFR--LYGLILLI-----LIFRIAGYVAXKM 671


>WHIT_ANOGA (Q27256) White protein
          Length = 695

 Score =  194 bits (492), Expect = 8e-49
 Identities = 145/551 (26%), Positives = 262/551 (47%), Gaps = 34/551 (6%)

Query: 26  RNRGVIEDKLVLLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKTGGY-IGGNIT-- 82
           R R     +  LLK ++G  + G L A+MG +GAGKTTL++ L+ R   G  I  N    
Sbjct: 104 RQRKDFNPRKHLLKNVTGVAKSGELLAVMGSSGAGKTTLLNALAFRSPPGVKISPNAVRA 163

Query: 83  ISGYPKKQETFARISGYCEQTDIHSPHVTVYESLLYSAWLRLSPDINAETRKMFIEEVME 142
           ++G P   E       Y +Q D+  P +T  E LL+ A LR+  D+ A  ++  ++EV++
Sbjct: 164 LNGVPVNAEQLRARCAYVQQDDLFIPSLTTREHLLFQAMLRMGRDVPASVKQHRVQEVLQ 223

Query: 143 LVELKPLRYALVGLPG-VSGLSTEQRKRLTVAVELVANPSIIFMDEPTSGLDARAAAIVM 201
            + L      ++G PG + GLS  +RKRL  A E + +P ++  DEPTSGLD+  A  V+
Sbjct: 224 ELSLVKCADTIIGAPGRIKGLSGGERKRLAFASETLTDPHLLLCDEPTSGLDSFMAHSVL 283

Query: 202 RAVRNTVDTGRTVVCTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNSSNLINYFEGV 261
           + ++     G+T++ TIHQPS +++  FD++LL+ +G       P  + S+   +   G+
Sbjct: 284 QVLKGMAMKGKTIILTIHQPSSELYCLFDKILLVAEGRVAFLGSP--YQSAEFFSQL-GI 340

Query: 262 QGVSKIKDGYNPATWMLEV--TTSSKEVELRIDYAEVYKNSELYRRNKALIKELSAPAPC 319
                    YNPA + +++     +KE E R    ++  +  +    + +++  S     
Sbjct: 341 ----PCPPNYNPADFYVQMLAIAPAKEAECRDMIKKICDSFAVSPIAREVLETASVAGKG 396

Query: 320 SKDLYF--------PSRYSRSFFTQCIACLWKQHWSYWRNPEYNAIRFLYSTAVAVLLGS 371
             + Y          + Y  S++TQ    LW+   S  ++P    +R L +  VA L+GS
Sbjct: 397 MDEPYMLQQVEGVGSTGYRSSWWTQFYCILWRSWLSVLKDPMLVKVRLLQTAMVATLIGS 456

Query: 372 MFWNLGSKIEKDQDLFNAMGSMYAAVILIGAMNSNSVQPVVGVERTVFYRERAARMYSAF 431
           +++  G  +++D  + N  GS++  +  +   N  +V  V   E  VF RE+ +R+Y   
Sbjct: 457 IYF--GQVLDQD-GVMNINGSLFLFLTNMTFQNVFAVINVFSAELPVFLREKRSRLYRVD 513

Query: 432 PYALAQVVIQLPYVFVQAVVYGIVVYVMIGFEWTLVKVVWCLFFMYFTFLYFTFYGMMSV 491
            Y L + + +LP       V+  + Y MIG        +  LF +       T +G +  
Sbjct: 514 TYFLGKTIAELPLFIAVPFVFTSITYPMIGLRTGATHYLTTLFIVTLVANVSTSFGYLIS 573

Query: 492 AMTPNNHISIIVSSAFYSVWNLFSGFVLPRPGK**LISVILSIPVWWRWYSWANPVAWSL 551
             + +  +++ V       + +F GF L             S+P ++++ S+ +   ++ 
Sbjct: 574 CASSSISMALSVGPPVVIPFLIFGGFFLNS----------ASVPAYFKYLSYLSWFRYAN 623

Query: 552 YGLVTSQYGDV 562
             L+ +Q+  V
Sbjct: 624 EALLINQWSTV 634


>YQ5C_CAEEL (Q09466) Putative ABC transporter C16C10.12 in
           chromosome III
          Length = 610

 Score =  179 bits (454), Expect = 2e-44
 Identities = 156/588 (26%), Positives = 275/588 (46%), Gaps = 45/588 (7%)

Query: 37  LLKGLSGAFRPGVLTALMGVTGAGKTTLMDVLSGRKTGGYI-GGNITISGYPKKQETFAR 95
           LL  +SG  +PG + ALMG +GAGKTTLM+VL  R   G    G + ++G  K  +  + 
Sbjct: 56  LLNRVSGIAKPGEMVALMGASGAGKTTLMNVLMCRNMKGLEKNGTVKVNG-TKIGKEISL 114

Query: 96  ISGYCEQTDIHSPHVTVYESLLYSAWLRLSPDINAETRKMFIEEVMELVELKPLRYALVG 155
           ISG+ +Q +I  P +TV E L+  A LR+    N  TR+  ++E++E++ L+  R   +G
Sbjct: 115 ISGFAQQQEIFIPTLTVDEYLMIQARLRMKA--NKHTRRERVDEIIEMLRLQNCRDLKIG 172

Query: 156 LPG-VSGLSTEQRKRLTVAVELVANPSIIFMDEPTSGLDARAAAIVMRAVRNTVDTGRTV 214
            PG V G+S  + +RLT A EL++NPS++F DEPTSGLD+  AA V++ ++N  ++GRT+
Sbjct: 173 TPGLVKGISGGEARRLTFACELLSNPSLLFADEPTSGLDSFMAASVVQILKNLANSGRTL 232

Query: 215 VCTIHQPSIDIFESFDELLLLKQGGQEIYVGPLGHNSSNLINYFEGVQGVSKIKDGYNPA 274
              IHQP+ ++F  FD+++ L  G       P  H S   + +F        I   +NP 
Sbjct: 233 ---IHQPTAELFFQFDKIIFLSMGKTAFMGTP--HES---VKFFADCG--HPIPKLFNPP 282

Query: 275 TWM---LEV----TTSSKEVELRIDYAEVYKNSELYRRNKALIKELSAPAPCSKDLYFPS 327
            W+   L V     T S+E   +I   E Y+ S +++++   I E+   A      Y   
Sbjct: 283 EWIQSKLSVIPNNETKSRETIGKI--IEFYEKSIIHQKS---IVEIRVIATTELPPYIE- 336

Query: 328 RYSRSFFTQCIACLWKQHWSYWRNPEYNAIRFLYSTAVAVLLGSMFWNLGSKIEKDQDLF 387
             +  FF +  A L +      R+P    ++ +    + + +GS++W    +    + + 
Sbjct: 337 --NPGFFAETGALLKRACLDVIRSPAQMRMKLIQKVVMGLFIGSLYW---QQPLDPRGVR 391

Query: 388 NAMGSMYAAVILIGAMNSNSVQPVVGVERTVFYRERAARMYSAFPYALAQVVIQLPYVFV 447
           N   ++Y  +  +       +   +  E  +  RE    ++    Y +++ +  LP   +
Sbjct: 392 NTNSALYFLIAELTFSTMFGIMTFMEHELPLIAREYHDGLFYVISYYISRFLSYLPLFTI 451

Query: 448 QAVVYGIVVYVMIGFEWTLVKVVWCLFFMYFTFLYFTFYGMMSVAMTPNNHISIIVSSAF 507
              +  ++ Y MIG   T  +V   +          T  G+    +     ++I  +   
Sbjct: 452 DGALMIVISYWMIGLNSTWQQVAKSILISVLVEQSATSCGLFLACLFETTSLAIAFAVPA 511

Query: 508 YSVWNLFSGFVLPRPGK**LISVILSIPVWWRWYSWANPVAWSLYGLVTSQYGDVKQNIE 567
             ++ L SG          L     + PV+ RW  W +   +   GLV +Q+  V     
Sbjct: 512 SGLFALLSG----------LYGNTNNFPVYIRWMQWTSWCRYGFEGLVVNQWSQVDNPKW 561

Query: 568 TSDGRQTV-EDFLRNYFGFKHDFLGVVALVNIAFPIVFALVFAIAIKM 614
               R+ + + F  N   ++ D +G+ ++V I F +   +   I I++
Sbjct: 562 DPFYRELILKQFSFNKDNYQLDVIGLCSIV-IFFYLAGYIALFIRIRL 608


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.326    0.140    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,372,858
Number of Sequences: 164201
Number of extensions: 3124719
Number of successful extensions: 13665
Number of sequences better than 10.0: 921
Number of HSP's better than 10.0 without gapping: 707
Number of HSP's successfully gapped in prelim test: 214
Number of HSP's that attempted gapping in prelim test: 11579
Number of HSP's gapped (non-prelim): 1542
length of query: 619
length of database: 59,974,054
effective HSP length: 116
effective length of query: 503
effective length of database: 40,926,738
effective search space: 20586149214
effective search space used: 20586149214
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 69 (31.2 bits)