BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC148526.6 + phase: 0 /pseudo
         (420 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

MYCT_HUMAN (Q96QE2) Proton myo-inositol cotransporter (H(+)-myo-...   201  2e-51
MYCT_RAT (Q921A2) Proton myo-inositol cotransporter (H(+)-myo-in...   199  1e-50
CSBC_BACSU (P46333) Probable metabolite transport protein csbC        168  2e-41
GALP_ECOLI (P37021) Galactose-proton symporter (Galactose transp...   159  1e-38
ITR1_SCHPO (Q10286) Myo-inositol transporter 1                        158  3e-38
XYLT_LACBR (O52733) D-xylose-proton symporter (D-xylose transpor...   151  3e-36
ITR2_SCHPO (P87110) Myo-inositol transporter 2                        150  6e-36
GTR1_LEIDO (Q01440) Membrane transporter D1                           149  1e-35
ITR1_YEAST (P30605) Myo-inositol transporter 1                        147  5e-35
ITR2_YEAST (P30606) Myo-inositol transporter 2                        142  2e-33
HUP2_CHLKE (Q39524) H(+)/hexose cotransporter 2 (Galactose-H+ sy...   118  2e-26
GT10_HUMAN (O95528) Solute carrier family 2, facilitated glucose...   110  7e-24
HEX6_RICCO (Q07423) Hexose carrier protein HEX6                       109  2e-23
HUP1_CHLKE (P15686) H(+)/hexose cotransporter 1                       108  3e-23
HXT5_YEAST (P38695) Probable glucose transporter HXT5                 107  4e-23
KHT2_KLULA (P53387) Hexose transporter 2                              107  7e-23
HXT7_YEAST (P39004) High-affinity hexose transporter HXT6             105  3e-22
HXT6_YEAST (P39003) High-affinity hexose transporter HXT6             105  3e-22
HXT4_YEAST (P32467) Low-affinity glucose transporter HXT4 (Low-a...   104  5e-22
GTR8_HUMAN (Q9NY64) Solute carrier family 2, facilitated glucose...   103  8e-22

>MYCT_HUMAN (Q96QE2) Proton myo-inositol cotransporter
           (H(+)-myo-inositol cotransporter) (Hmit)
          Length = 629

 Score =  201 bits (512), Expect = 2e-51
 Identities = 130/379 (34%), Positives = 199/379 (52%), Gaps = 47/379 (12%)

Query: 34  GGLLFGYDTGVISGASLYIRDEFEQVDKKPWLQETIVSMASAGAIIGAAFGGYMNDKMGR 93
           GG LFGYDTGV+SGA L ++    Q+      QE +VS     A + A  GG +N   GR
Sbjct: 72  GGFLFGYDTGVVSGAMLLLK---RQLSLDALWQELLVSSTVGAAAVSALAGGALNGVFGR 128

Query: 94  KKTILMADVVFVAGALVMAAAPAPWVIIIGRLLVGLGVGAASMTAPLYISEASPAKIRGA 153
           +  IL+A  +F AG+ V+AAA     ++ GRL+VGLG+G ASMT P+YI+E SP  +RG 
Sbjct: 129 RAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGR 188

Query: 154 LVCRLHQWFTHNRWSISLLPHQFGIYQ-------------------------------VY 182
           LV     + T  ++  S++   F   Q                               + 
Sbjct: 189 LVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAXVPAVIQFFGFLFLPESPRWLI 248

Query: 183 RQSKEEEAKQILSKIYRPGEVEEEMKAMHESIEAEKAEDGLIGHSLAQKLKGAWSNDVVR 242
           ++ + ++A++ILS++     ++EE  ++  +IE E+ E G  G  + + L    S    R
Sbjct: 249 QKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSAGPVICRML----SYPPTR 304

Query: 243 RGLYAGITVQVVQQIVGINTIMYYSPTIVQFAGIASNSTAFALSLVTSGLNAVGTIVSMV 302
           R L  G  +Q+ QQ+ GINTIMYYS TI+Q +G+  +  A  L+ VT+  N + T+V + 
Sbjct: 305 RALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTAFTNFIFTLVGVW 364

Query: 303 LIDRFGRRKLMLISLIGIFVSLVTLSVTFNQAAHHAPSLSIQDSLSFGGNSTCKAYTTAP 362
           L+++ GRRKL   SL G  V+L+ L++ F  +A  +P ++ +     G N+TC  Y+   
Sbjct: 365 LVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSPRITFKPIAPSGQNATCTRYS--- 421

Query: 363 NHLSWNCMQC-LHEDCAFC 380
                 C +C L  DC FC
Sbjct: 422 -----YCNECMLDPDCGFC 435


>MYCT_RAT (Q921A2) Proton myo-inositol cotransporter
           (H(+)-myo-inositol cotransporter) (Hmit)
          Length = 618

 Score =  199 bits (505), Expect = 1e-50
 Identities = 129/379 (34%), Positives = 198/379 (52%), Gaps = 47/379 (12%)

Query: 34  GGLLFGYDTGVISGASLYIRDEFEQVDKKPWLQETIVSMASAGAIIGAAFGGYMNDKMGR 93
           GG LFGYDTGV+SGA L +R    Q+      QE +VS A   A + A  GG +N  +GR
Sbjct: 61  GGFLFGYDTGVVSGAMLLLR---RQMRLGAMWQELLVSGAVGAAAVAALAGGALNGALGR 117

Query: 94  KKTILMADVVFVAGALVMAAAPAPWVIIIGRLLVGLGVGAASMTAPLYISEASPAKIRGA 153
           +  IL+A  +   G+ V+AAA     ++ GRL+VGLG+G ASMT P+YI+E SP  +RG 
Sbjct: 118 RSAILLASALCTVGSAVLAAAANKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGR 177

Query: 154 LVCRLHQWFTHNRWSISLLPHQFGIYQ-------------------------------VY 182
           LV     + T  ++  S++   F   Q                               + 
Sbjct: 178 LVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAIPAVIQFLGFLFLPESPRWLI 237

Query: 183 RQSKEEEAKQILSKIYRPGEVEEEMKAMHESIEAEKAEDGLIGHSLAQKLKGAWSNDVVR 242
           ++ + ++A++ILS++     ++EE  ++  SIE E+ E    G  + + L    S    R
Sbjct: 238 QKGQTQKARRILSQMRGNQTIDEEYDSIRNSIEEEEKEASAAGPIICRML----SYPPTR 293

Query: 243 RGLYAGITVQVVQQIVGINTIMYYSPTIVQFAGIASNSTAFALSLVTSGLNAVGTIVSMV 302
           R L  G  +Q+ QQ+ GINTIMYYS TI+Q +G+  +  A  L+ +T+  N + T+V + 
Sbjct: 294 RALAVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASITAFTNFIFTLVGVW 353

Query: 303 LIDRFGRRKLMLISLIGIFVSLVTLSVTFNQAAHHAPSLSIQDSLSFGGNSTCKAYTTAP 362
           L+++ GRRKL   SL G  V+L  L++ F  +A  +P ++ + +   G N+TC  Y+   
Sbjct: 354 LVEKVGRRKLTFGSLAGTTVALTILALGFLLSAQVSPRVTFRPTAPSGQNATCTEYS--- 410

Query: 363 NHLSWNCMQC-LHEDCAFC 380
                 C +C L  DC FC
Sbjct: 411 -----YCNECMLDPDCGFC 424


>CSBC_BACSU (P46333) Probable metabolite transport protein csbC
          Length = 461

 Score =  168 bits (426), Expect = 2e-41
 Identities = 111/324 (34%), Positives = 172/324 (52%), Gaps = 44/324 (13%)

Query: 34  GGLLFGYDTGVISGASLYIRDEFEQVDKKPWLQETIVSMASAGAIIGAAFGGYMNDKMGR 93
           GGLL+GYDTGVISGA L+I ++         L   +VSM   GAI G+A  G  +D+ GR
Sbjct: 17  GGLLYGYDTGVISGALLFINNDIPLTTLTEGL---VVSMLLLGAIFGSALSGTCSDRWGR 73

Query: 94  KKTILMADVVFVAGALVMAAAPAPWVIIIGRLLVGLGVGAASMTAPLYISEASPAKIRGA 153
           +K + +  ++F+ GAL  A +    ++I  R+++GL VG ++   P+Y+SE +P KIRG 
Sbjct: 74  RKVVFVLSIIFIIGALACAFSQTIGMLIASRVILGLAVGGSTALVPVYLSEMAPTKIRGT 133

Query: 154 L-----------------VCRLHQWFTHNRWSISLLPHQFGIYQV------------YRQ 184
           L                 V  L   F   RW + L      +  +             ++
Sbjct: 134 LGTMNNLMIVTGILLAYIVNYLFTPFEAWRWMVGLAAVPAVLLLIGIAFMPESPRWLVKR 193

Query: 185 SKEEEAKQILSKIYRPGEVEEEMKAMHESIEAEKAEDGLIGHSLAQKLKGAWSNDVVRRG 244
             EEEA++I++  + P ++E E+  M +  EAEK E  L        LK  W    +R  
Sbjct: 194 GSEEEARRIMNITHDPKDIEMELAEMKQG-EAEKKETTL------GVLKAKW----IRPM 242

Query: 245 LYAGITVQVVQQIVGINTIMYYSPTIVQFAGIASNSTAFALSLVTSGLNAVGTIVSMVLI 304
           L  G+ + + QQ VGINT++YY+PTI   AG+ ++++A   ++    LN +  I +M+LI
Sbjct: 243 LLIGVGLAIFQQAVGINTVIYYAPTIFTKAGLGTSASALG-TMGIGILNVIMCITAMILI 301

Query: 305 DRFGRRKLMLISLIGIFVSLVTLS 328
           DR GR+KL++   +GI +SL  LS
Sbjct: 302 DRVGRKKLLIWGSVGITLSLAALS 325


>GALP_ECOLI (P37021) Galactose-proton symporter (Galactose
           transporter)
          Length = 464

 Score =  159 bits (403), Expect = 1e-38
 Identities = 109/337 (32%), Positives = 174/337 (51%), Gaps = 37/337 (10%)

Query: 30  LALSGGLLFGYDTGVISGASLYIRDEFEQVDKKPWLQETIVSMASAGAIIGAAFGGYMND 89
           LA   GLLFG D GVI+GA  +I DEF+        QE +VS    GA +GA   G+++ 
Sbjct: 21  LAALAGLLFGLDIGVIAGALPFIADEFQITSHT---QEWVVSSMMFGAAVGAVGSGWLSF 77

Query: 90  KMGRKKTILMADVVFVAGALVMAAAPAPWVIIIGRLLVGLGVGAASMTAPLYISEASPAK 149
           K+GRKK++++  ++FVAG+L  AAAP   V+I+ R+L+GL VG AS TAPLY+SE +P K
Sbjct: 78  KLGRKKSLMIGAILFVAGSLFSAAAPNVEVLILSRVLLGLAVGVASYTAPLYLSEIAPEK 137

Query: 150 IRGALVCRLHQWFTHN-----------------RW--SISLLPH---QFGIYQVYRQSKE 187
           IRG+++       T                   RW   + ++P      G++ +    + 
Sbjct: 138 IRGSMISMYQLMITIGILGAYLSDTAFSYTGAWRWMLGVIIIPAILLLIGVFFLPDSPRW 197

Query: 188 EEAKQILSKIYRPGEVEEEMKAMHESIEAEKAEDGLIGHSLAQKLKGAWS----NDVVRR 243
             AK+      R  + E  +  + ++    K E   I  SL  K  G W+    N   RR
Sbjct: 198 FAAKR------RFVDAERVLLRLRDTSAEAKRELDEIRESLQVKQSG-WALFKENSNFRR 250

Query: 244 GLYAGITVQVVQQIVGINTIMYYSPTIVQFAGIASNSTAFALSLVTSGLNAVGTIVSMVL 303
            ++ G+ +QV+QQ  G+N IMYY+P I + AG  + +     +++    N + T +++ L
Sbjct: 251 AVFLGVLLQVMQQFTGMNVIMYYAPKIFELAGYTNTTEQMWGTVIVGLTNVLATFIAIGL 310

Query: 304 IDRFGRRKLMLISLIGIFVSLVTLSVTFNQAAHHAPS 340
           +DR+GR+  + +  + +   +  L  T      H+PS
Sbjct: 311 VDRWGRKPTLTLGFLVMAAGMGVLG-TMMHIGIHSPS 346


>ITR1_SCHPO (Q10286) Myo-inositol transporter 1
          Length = 575

 Score =  158 bits (399), Expect = 3e-38
 Identities = 106/332 (31%), Positives = 169/332 (49%), Gaps = 38/332 (11%)

Query: 34  GGLLFGYDTGVISGASLYIRDEFEQVDKKPWLQETIVSMASAGAIIGAAFGGYMNDKMGR 93
           GGLLFGYDTGVISGA + I       +     +E I S  S GA++G    G + D  GR
Sbjct: 97  GGLLFGYDTGVISGALVVIGTSLGGHELTNGGKEFITSATSLGALLGGIIAGALADFFGR 156

Query: 94  KKTILMADVVFVAGALVMAAAPAPWVIIIGRLLVGLGVGAASMTAPLYISEASPAKIRGA 153
           K  I +A ++ + G++V   A   W +I+GR ++G GVG AS+  PLY+SE +P+KIRG 
Sbjct: 157 KPVIAIASIIIIVGSIVQVTAHHLWHMIVGRFVIGWGVGIASLIIPLYLSEIAPSKIRGR 216

Query: 154 LVCRLHQWFT----------------HNRW----SISLLPHQFGIY----------QVYR 183
           LV       T                HN W     ++++P  F ++           + +
Sbjct: 217 LVIIYVLLITAGQVIAYGIDTAFEHVHNGWRWMVGLAMVPAAFQLFILIWLPESPRLLVK 276

Query: 184 QSKEEEAKQILSKIY---RPGEVEEEMKAMHESIEAEKAEDGLIGHSLAQKLKGAWSNDV 240
           + + +EA   L++IY    P E++ ++  + E +       G     + +  K  + N  
Sbjct: 277 KERSQEAYNTLARIYPTAHPYEIKTKLYLIQEGV--RDPFSGSRWQKIVKTFKELYFNPS 334

Query: 241 VRRGLYAGITVQVVQQIVGINTIMYYSPTIVQFAGIASNSTAFALSLVTSGLNAVGTIVS 300
             R L     +Q +QQ+ G N++MY+S TI +  G  +N T  A  L+ +  N V TIV+
Sbjct: 335 NFRALILACGLQAMQQLSGFNSLMYFSSTIFEVVGF-NNPT--ATGLIIAATNFVFTIVA 391

Query: 301 MVLIDRFGRRKLMLISLIGIFVSLVTLSVTFN 332
             +ID FGRR L+L+++ G+  +L+  +V F+
Sbjct: 392 FGVIDFFGRRILLLLTVWGMIAALIVCAVAFH 423


>XYLT_LACBR (O52733) D-xylose-proton symporter (D-xylose
           transporter)
          Length = 457

 Score =  151 bits (382), Expect = 3e-36
 Identities = 100/324 (30%), Positives = 171/324 (51%), Gaps = 40/324 (12%)

Query: 34  GGLLFGYDTGVISGASLYIRDEFEQVDKKPWLQETIVSMASAGAIIGAAFGGYMNDKMGR 93
           GGLLFGYDTGVISGA L+I+   +Q++   W Q  +VS    GAI+GAA  G  +D+ GR
Sbjct: 16  GGLLFGYDTGVISGAILFIQ---KQMNLGSWQQGWVVSAVLLGAILGAAIIGPSSDRFGR 72

Query: 94  KKTILMADVVFVAGALVMAAAPAPWVIIIGRLLVGLGVGAASMTAPLYISEASPAKIRGA 153
           +K +L++ ++F  GAL  A +P  W +II R+++G+ VGAAS   P Y++E +P+  RG 
Sbjct: 73  RKLLLLSAIIFFVGALGSAFSPEFWTLIISRIILGMAVGAASALIPTYLAELAPSDKRGT 132

Query: 154 LVCRLHQ-------------------WFTHNRWSISLLPHQFGIYQVYRQSKEEEAKQIL 194
            V  L Q                   ++T  RW +        +  +      E  + ++
Sbjct: 133 -VSSLFQLMVMTGILLAYITNYSFSGFYTGWRWMLGFAAIPAALLFLGGLILPESPRFLV 191

Query: 195 SKIYRPGEVEEEMKAM-----HESIEAEKAEDGLIGHSLAQKLKGAWS---NDVVRRGLY 246
               + G ++E    +     H+ +   K  + +     A+ + G WS     +VR  L 
Sbjct: 192 ----KSGHLDEARHVLDTMNKHDQVAVNKEINDI--QESAKIVSGGWSELFGKMVRPSLI 245

Query: 247 AGITVQVVQQIVGINTIMYYSPTIVQFAGIASNSTAFALSLVTSGL-NAVGTIVSMVLID 305
            GI + + QQ++G NT++YY+PTI  F  +    +A  L+ +  G+ N + T +++ ++D
Sbjct: 246 IGIGLAIFQQVMGCNTVLYYAPTI--FTDVGFGVSAALLAHIGIGIFNVIVTAIAVAIMD 303

Query: 306 RFGRRKLMLISLIGIFVSLVTLSV 329
           +  R+K++ I  +G+ +SL  +S+
Sbjct: 304 KIDRKKIVNIGAVGMGISLFVMSI 327


>ITR2_SCHPO (P87110) Myo-inositol transporter 2
          Length = 557

 Score =  150 bits (379), Expect = 6e-36
 Identities = 108/355 (30%), Positives = 173/355 (48%), Gaps = 42/355 (11%)

Query: 27  LMRLALSGGLLFGYDTGVISGASLYIRDEFEQVDKKPWLQETIVSMASAGAIIGAAFGGY 86
           L  +A   GLLFGYDTGVISGA   +  +   V      +E I S  S  A+I A   G+
Sbjct: 84  LSAVAGISGLLFGYDTGVISGALAVLGSDLGHV-LSSGQKELITSATSFAALISATTSGW 142

Query: 87  MNDKMGRKKTILMADVVFVAGALVMAAAPAPWVIIIGRLLVGLGVGAASMTAPLYISEAS 146
           + D +GRK+ +L AD +FV G+++MAA+    ++++GR +VG G+G  S+  P+YI+E +
Sbjct: 143 LADWVGRKRLLLCADAIFVIGSVIMAASRNVAMMVVGRFIVGYGIGLTSLIVPMYITELA 202

Query: 147 PAKIRGALVCRLHQWFT----------------HNRWS--------------ISLLPHQF 176
           PA++RG LV     + T                H  W               ISL     
Sbjct: 203 PARLRGRLVIIYVVFITGGQLIAYSLNAAFEHVHQGWRIMFGIGAAPALGQLISLFWTPE 262

Query: 177 GIYQVYRQSKEEEAKQILSKIY---RPGEVEEEMKAMHESIEAEKAEDGLIGHSLAQKLK 233
               + R +  E+  +ILS+I+   +P E+  ++  + E ++ +  E     H     LK
Sbjct: 263 SPRYLLRHNHVEKVYKILSRIHPEAKPAEIAYKVSLIQEGVKVDFPEGNKFQH-FFHSLK 321

Query: 234 GAWSNDVVRRGLYAGITVQVVQQIVGINTIMYYSPTIVQFAGIASNSTAFALSLVTSGLN 293
             ++    RR L+ G  +Q  QQ  G N I Y+S  I Q  G      + ++S+V    N
Sbjct: 322 VLFTVPSNRRSLFIGCFLQWFQQFSGTNAIQYFSAIIFQSVGF---KNSISVSIVVGATN 378

Query: 294 AVGTIVSMVLIDRFGRRKLMLISLIGIFVSLVTLSVTFNQAAHHAPSLSIQDSLS 348
            V TIV+ + IDR GRR+++L +   +   L   ++ +    H  P+ + Q++ S
Sbjct: 379 FVFTIVAFMFIDRIGRRRILLCTSAVMIAGLALCAIAY----HFLPADTTQNTNS 429


>GTR1_LEIDO (Q01440) Membrane transporter D1
          Length = 547

 Score =  149 bits (377), Expect = 1e-35
 Identities = 104/330 (31%), Positives = 172/330 (51%), Gaps = 37/330 (11%)

Query: 27  LMRLALSGGLLFGYDTGVISGASLYIRDEFEQVDKKPWLQETIVSMASAGAIIGAAFGGY 86
           +M  A  GG LFGYDTGVI+ A   ++D F    +  W    IV++A AGA +GA   G+
Sbjct: 5   VMLCAALGGFLFGYDTGVINAALFQMKDHFG-FSEHSWQYALIVAIAIAGAFVGAFISGF 63

Query: 87  MNDKMGRKKTILMADVVFVAGALVMAAAPAPWVIIIGRLLVGLGVGAASMTAPLYISEAS 146
           ++   GR+  I +AD +FV G+++M AAP   V+++ R++VGL +G +S T P+Y++E +
Sbjct: 64  ISAAFGRRPCIAVADALFVIGSVLMGAAPNVEVVLVSRVIVGLAIGISSATIPVYLAEVT 123

Query: 147 PAKIRGALVCRLHQWFTHNR-------------------WSISL----LPHQFGIYQVY- 182
             K RGA +   + + T  +                   W +++    LP    + Q + 
Sbjct: 124 SPKHRGATIVLNNLFLTGGQFVAAGFTAIMVVFTSKNIGWRVAIGIGALP---AVVQAFC 180

Query: 183 -RQSKEEEAKQILSKIYRPGEVEEEMKAMHESIEAEKAE--DGLIGHSLAQKLKGAWSND 239
                 E  + +LSK +      +  KA+ +  E +  E  +G    S+    +   + D
Sbjct: 181 LLFFLPESPRWLLSKGH-----ADRAKAVADKFEVDLCEFQEGDELPSVRIDYRPLMARD 235

Query: 240 VVRRGLYAGITVQVVQQIVGINTIMYYSPTIVQFAGIASNSTAFALSLVTSGLNAVGTIV 299
            +R  +     +Q++QQ  GINTIMYYS  I+  AG         LS+  + +NA+ T V
Sbjct: 236 -MRFRVVLSSGLQIIQQFSGINTIMYYSSVILYDAGFRDAIMPVVLSIPLAFMNALFTAV 294

Query: 300 SMVLIDRFGRRKLMLISLIGIFVSLVTLSV 329
           ++  +DRFGRR+++LIS+ G  V LV +++
Sbjct: 295 AIFTVDRFGRRRMLLISVFGCLVLLVVIAI 324


>ITR1_YEAST (P30605) Myo-inositol transporter 1
          Length = 584

 Score =  147 bits (371), Expect = 5e-35
 Identities = 109/349 (31%), Positives = 176/349 (50%), Gaps = 49/349 (14%)

Query: 24  SPYLMRL---ALSGGLLFGYDTGVISGASLYIRDEFEQVDKKPWLQETIVSMASAGAIIG 80
           SP+++ L   A   G +FGYDTG IS A + I  + +        +E + +  S GA+I 
Sbjct: 83  SPFIITLTFVASISGFMFGYDTGYISSALISIGTDLDHKVLTYGEKEIVTAATSLGALIT 142

Query: 81  AAFGGYMNDKMGRKKTILMADVVFVAGALVMAAAPAPWVIIIGRLLVGLGVGAASMTAPL 140
           + F G   D  GRK+ ++ ++++FV GA++  +A   W + +GRL++G GVG  S+ APL
Sbjct: 143 SIFAGTAADIFGRKRCLMGSNLMFVIGAILQVSAHTFWQMAVGRLIMGFGVGIGSLIAPL 202

Query: 141 YISEASPAKIRGALVCRLHQWFT----------------HNRWSI----SLLPH--QFGI 178
           +ISE +P  IRG L      W T                +N W I    SL+P   QF  
Sbjct: 203 FISEIAPKMIRGRLTVINSLWLTGGQLVAYGCGAGLNYVNNGWRILVGLSLIPTAVQFTC 262

Query: 179 ---------YQVYRQSKEEEAKQILSKIYRPGEVE------EEMKAMHESIEAEKAEDGL 223
                    Y V +      A ++L + Y     E      EE+  +++SI  +   + +
Sbjct: 263 LCFLPDTPRYYVMKGDLAR-ATEVLKRSYTDTSEEIIERKVEELVTLNQSIPGKNVPEKV 321

Query: 224 IGHSLAQKLKGAWSNDVVRRGLYAGITVQVVQQIVGINTIMYYSPTIVQFAGIASNSTAF 283
              +  ++L    SN    R L  G  +Q +QQ  G N++MY+S TI +  G  ++S   
Sbjct: 322 --WNTIKELHTVPSN---LRALIIGCGLQAIQQFTGWNSLMYFSGTIFETVGFKNSS--- 373

Query: 284 ALSLVTSGLNAVGTIVSMVLIDRFGRRKLMLISLIGIFVSLVTLSVTFN 332
           A+S++ SG N + T+V+   ID+ GRR ++LI L G+ ++LV  S+ F+
Sbjct: 374 AVSIIVSGTNFIFTLVAFFSIDKIGRRTILLIGLPGMTMALVVCSIAFH 422


>ITR2_YEAST (P30606) Myo-inositol transporter 2
          Length = 612

 Score =  142 bits (358), Expect = 2e-33
 Identities = 106/348 (30%), Positives = 172/348 (48%), Gaps = 47/348 (13%)

Query: 24  SPYLMRL---ALSGGLLFGYDTGVISGASLYIRDEFEQVDKKPWLQETIVSMASAGAIIG 80
           SP+++ L   A   G +FGYDTG IS A + I  + +        +E I +  S GA+I 
Sbjct: 109 SPFIITLTFVASISGFMFGYDTGYISSALISINRDLDNKVLTYGEKELITAATSLGALIT 168

Query: 81  AAFGGYMNDKMGRKKTILMADVVFVAGALVMAAAPAPWVIIIGRLLVGLGVGAASMTAPL 140
           +   G   D  GR+  ++ ++++F+ GA++   A   W +  GRL++G GVG  S+ +PL
Sbjct: 169 SVGAGTAADVFGRRPCLMFSNLMFLIGAILQITAHKFWQMAAGRLIMGFGVGIGSLISPL 228

Query: 141 YISEASPAKIRGALVCRLHQWFT----------------HNRWSI----SLLPH--QFGI 178
           +ISE +P  IRG L      W T                 N W I    SL+P   QF  
Sbjct: 229 FISEIAPKMIRGRLTVINSLWLTGGQLIAYGCGAGLNHVKNGWRILVGLSLIPTVLQFSF 288

Query: 179 Y--------QVYRQSKEEEAKQILSKIYRPGEVE------EEMKAMHESIEAEKAEDGLI 224
           +            +   + AK +L + Y   E E      EE+ ++++SI  +       
Sbjct: 289 FCFLPDTPRYYVMKGDLKRAKMVLKRSYVNTEDEIIDQKVEELSSLNQSIPGKNPITKF- 347

Query: 225 GHSLAQKLKGAWSNDVVRRGLYAGITVQVVQQIVGINTIMYYSPTIVQFAGIASNSTAFA 284
             ++ ++L    SN    R L  G  +Q +QQ  G N++MY+S TI +  G  ++S   A
Sbjct: 348 -WNMVKELHTVPSN---FRALIIGCGLQAIQQFTGWNSLMYFSGTIFETVGFKNSS---A 400

Query: 285 LSLVTSGLNAVGTIVSMVLIDRFGRRKLMLISLIGIFVSLVTLSVTFN 332
           +S++ SG N V T+++   ID+ GRR ++LI L G+ V+LV  ++ F+
Sbjct: 401 VSIIVSGTNFVFTLIAFFCIDKIGRRYILLIGLPGMTVALVICAIAFH 448


>HUP2_CHLKE (Q39524) H(+)/hexose cotransporter 2 (Galactose-H+
           symporter)
          Length = 540

 Score =  118 bits (296), Expect = 2e-26
 Identities = 115/398 (28%), Positives = 177/398 (43%), Gaps = 72/398 (18%)

Query: 4   GGHPLADKTEFTEC---WRRTAESPYLMRLAL---SGGLLFGYDTGVISGA--------- 48
           GG P+A  T        + R   + Y+  +AL   SGGLLFGYD GV  G          
Sbjct: 3   GGGPVASTTTNRASQYGYARGGLNWYIFIVALTAGSGGLLFGYDIGVTGGVTSMPEFLQK 62

Query: 49  ---SLYIRDEFEQVDKKPW-------LQETIVSMASAGAIIGAAFGGYMNDKMGRKKTIL 98
              S+Y R +     K P+       LQ    S   AG  + + F G +  + GRK T+L
Sbjct: 63  FFPSIYDRTQQPSDSKDPYCTYDDQKLQLFTSSFFLAGMFV-SFFAGSVVRRWGRKPTML 121

Query: 99  MADVVFVAGALVMAAAPAPWVIIIGRLLVGLGVGAASMTAPLYISEASPAKIRGAL---- 154
           +A V+F+AGA + A A    +++IGR+L+G GVG  +   PLY+SE +P K RG L    
Sbjct: 122 IASVLFLAGAGLNAGAQDLAMLVIGRVLLGFGVGGGNNAVPLYLSECAPPKYRGGLNMMF 181

Query: 155 ---------VCRLHQWFT---HNRWSIS----------------LLPHQFGIYQVYRQSK 186
                    V +L  + T   +N W +S                LLP       +  +  
Sbjct: 182 QLAVTIGIIVAQLVNYGTQTMNNGWRLSLGLAGVPAIILLIGSLLLPETPN--SLIERGH 239

Query: 187 EEEAKQILSKIYRPGEVEEEMKAMHESIEAEKAEDGLIGHSLAQKLKGAWSNDVVRRGLY 246
               + +L+++ R   V+ E + +     AE++    +  S A      +S  ++   L 
Sbjct: 240 RRRGRAVLARLRRTEAVDTEFEDI--CAAAEESTRYTLRQSWAALFSRQYSPMLIVTSLI 297

Query: 247 AGITVQVVQQIVGINTIMYYSPTIVQFAGIASNSTAFALSLVTSGLNAVGTIVSMVLIDR 306
           A     ++QQ+ GIN IM+Y P +    G A ++ A   +++   +N   T VS+  +D+
Sbjct: 298 A-----MLQQLTGINAIMFYVPVLFSSFGTARHA-ALLNTVIIGAVNVAATFVSIFSVDK 351

Query: 307 FGRRKLMLIS----LIGIFVSLVTLSVTFNQAAHHAPS 340
           FGRR L L       IG  V+   L V  N+   + PS
Sbjct: 352 FGRRGLFLEGGIQMFIGQVVTAAVLGVELNKYGTNLPS 389


>GT10_HUMAN (O95528) Solute carrier family 2, facilitated glucose
           transporter, member 10 (Glucose transporter type 10)
          Length = 541

 Score =  110 bits (275), Expect = 7e-24
 Identities = 92/329 (27%), Positives = 156/329 (46%), Gaps = 22/329 (6%)

Query: 25  PYLMRLALSGGLLFGYDTGVISGASLYIRDEFEQVDKKPWLQETIVSMASAGAIIGAAFG 84
           P    ++L GGL FGY+  VISGA L ++ +F     +   QE +V     GA++ +  G
Sbjct: 9   PLCASVSLLGGLTFGYELAVISGALLPLQLDFGLSCLE---QEFLVGSLLLGALLASLVG 65

Query: 85  GYMNDKMGRKKTILMADVVFVAGALVMAAAPAPWVIIIGRLLVGLGVGAASMTAPLYISE 144
           G++ D  GRK+ IL +++V +AG+L +  A +   +++GR +VG  +  +SM   +Y+SE
Sbjct: 66  GFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISLSSMACCIYVSE 125

Query: 145 ASPAKIRGALVCRLHQWFT-----HNRWSISLLPHQFGIYQVYRQSKEEEAKQILSKIYR 199
               + RG LV       T         + +L    +G   ++  +      Q LS ++ 
Sbjct: 126 LVGPRQRGVLVSLYEAGITVGILLSYALNYALAGTPWGWRHMFGWATAPAVLQSLSLLFL 185

Query: 200 PGEVEEEMKAMHESI------EAEKAEDGLIGHSLAQKLKGAWSNDVVRRGLYAGITVQV 253
           P   +E   A H+ +      EA K   G   +S     +   + D +R     G+ + +
Sbjct: 186 PAGTDE--TATHKDLIPLQGGEAPKLGPGRPRYSFLDLFR---ARDNMRGRTTVGLGLVL 240

Query: 254 VQQIVGINTIMYYSPTIVQFAGIASNSTAFALSLVTSGLNAVGTIVSMVLIDRFGRRKLM 313
            QQ+ G   ++ Y+ TI    G    S+A   S+    +    T+ +M L+DR GRR L+
Sbjct: 241 FQQLTGQPNVLCYASTIFSSVGFHGGSSAVLASVGLGAVKVAATLTAMGLVDRAGRRALL 300

Query: 314 L--ISLIGIFVSLVTLSVTFNQAAHHAPS 340
           L   +L+ + VS + L V+F       PS
Sbjct: 301 LAGCALMALSVSGIGL-VSFAVPMDSGPS 328


>HEX6_RICCO (Q07423) Hexose carrier protein HEX6
          Length = 510

 Score =  109 bits (272), Expect = 2e-23
 Identities = 90/350 (25%), Positives = 156/350 (43%), Gaps = 68/350 (19%)

Query: 30  LALSGGLLFGYDTGVISGASL---YIRDEFEQVDKK--------------PWLQETIVSM 72
           +A  GG++FGYD GV  G +    +++  F  V +K                L  +  S 
Sbjct: 28  MAAMGGVIFGYDIGVSGGVTSMDPFLKKFFPDVYRKMKEDTEISNYCKFDSQLLTSFTSS 87

Query: 73  ASAGAIIGAAFGGYMNDKMGRKKTILMADVVFVAGALVMAAAPAPWVIIIGRLLVGLGVG 132
                ++ + F   +    GRK +IL+   VF+A A +  AA   +++I GR+L+G+GVG
Sbjct: 88  LYVAGLVASFFASSVTRAFGRKPSILLGGXVFLAXAALGGAAVNVYMLIFGRVLLGVGVG 147

Query: 133 AASMTAPLYISEASPAKIRGA-------------LVCRLHQWFTHN-----RWSISLLPH 174
            A+   PLY+SE +P + RGA             L   L  + T        W ISL   
Sbjct: 148 FANQAVPLYLSEMAPPRYRGAINNGFQFSVGIGALSANLINYGTEKIEGGWGWRISLAMA 207

Query: 175 Q-------FGIY--------QVYRQSKEEEAKQILSKIYRPGEVEEEMKAMHESIEAEKA 219
                   FG           + R +  E AK +L ++    +V+ E+            
Sbjct: 208 AVPAAILTFGALFLPETPNSLIQRSNDHERAKLMLQRVRGTTDVQAEL------------ 255

Query: 220 EDGLIGHSLAQKLKGAWSNDVVRRG----LYAGITVQVVQQIVGINTIMYYSPTIVQFAG 275
            D LI  S+  +       +++RR     L   + +   QQ+ GIN I +Y+P + +  G
Sbjct: 256 -DDLIKASIISRTIQHPFKNIMRRKYRPQLVMAVAIPFFQQVTGINVIAFYAPILFRTIG 314

Query: 276 IASNSTAFALSLVTSGLNAVGTIVSMVLIDRFGRRKLMLISLIGIFVSLV 325
           +  +++  + S+VT  + +  T +SM+++D+ GRR L +   + +FV+ +
Sbjct: 315 LEESASLLS-SIVTGLVGSASTFISMLIVDKLGRRALFIFGGVQMFVAQI 363


>HUP1_CHLKE (P15686) H(+)/hexose cotransporter 1
          Length = 534

 Score =  108 bits (270), Expect = 3e-23
 Identities = 94/353 (26%), Positives = 152/353 (42%), Gaps = 67/353 (18%)

Query: 30  LALSGGLLFGYDTGVISGA---SLYIRDEFEQV--------DKKPW-------LQETIVS 71
           +A  GGLL GYD GV  G      + +  F  V        +  P+       LQ  + S
Sbjct: 33  MAACGGLLLGYDNGVTGGVVSLEAFEKKFFPDVWAKKQEVHEDSPYCTYDNAKLQLFVSS 92

Query: 72  MASAGAIIGAAFGGYMNDKMGRKKTILMADVVFVAGALVMAAAPAPWVIIIGRLLVGLGV 131
           +  AG ++   F  ++    GRK T+ +    FVAG LV A A    ++I+GR+L+G GV
Sbjct: 93  LFLAG-LVSCLFASWITRNWGRKVTMGIGGAFFVAGGLVNAFAQDMAMLIVGRVLLGFGV 151

Query: 132 GAASMTAPLYISEASPAKIRGALVCRLHQWFT----------------HNRWSISL---- 171
           G  S   P Y+SE +P   RG L      + T                 N W +SL    
Sbjct: 152 GLGSQVVPQYLSEVAPFSHRGMLNIGYQLFVTIGILIAGLVNYAVRDWENGWRLSLGPAA 211

Query: 172 ------------LPHQFGIYQVYRQSKEEEAKQILSKIYRPGEVEEEMKAMHESIEAEKA 219
                       LP       +  + K E+ +++L K+    EV+ E   +  ++E  + 
Sbjct: 212 APGAILFLGSLVLPESPNF--LVEKGKTEKGREVLQKLCGTSEVDAEFADIVAAVEIARP 269

Query: 220 EDGLIGHSLAQKLKGAWSNDVVRR---GLYAGITVQVVQQIVGINTIMYYSPTIVQFAGI 276
                       ++ +W++   RR    L     +Q  QQ  GIN I++Y P +    G 
Sbjct: 270 IT----------MRQSWASLFTRRYMPQLLTSFVIQFFQQFTGINAIIFYVPVLFSSLGS 319

Query: 277 ASNSTAFALSLVTSGLNAVGTIVSMVLIDRFGRRKLMLISLIGIFVSLVTLSV 329
           A NS A   ++V   +N   T+++++  D+FGRR L++   I   ++++T  V
Sbjct: 320 A-NSAALLNTVVVGAVNVGSTLIAVMFSDKFGRRFLLIEGGIQCCLAMLTTGV 371


>HXT5_YEAST (P38695) Probable glucose transporter HXT5
          Length = 592

 Score =  107 bits (268), Expect = 4e-23
 Identities = 96/337 (28%), Positives = 149/337 (43%), Gaps = 54/337 (16%)

Query: 34  GGLLFGYDTGVISG----ASLYIRDEFEQVDKKPWLQET----IVSMASAGAIIGAAFGG 85
           GG +FG+DTG ISG         R    + +   +L +     +VS+ + G  IG     
Sbjct: 96  GGFVFGWDTGTISGFVRQTDFIRRFGSTRANGTTYLSDVRTGLMVSIFNIGCAIGGIVLS 155

Query: 86  YMNDKMGRKKTILMADVVFVAGALVMAAAPAPWV-IIIGRLLVGLGVGAASMTAPLYISE 144
            + D  GRK  ++   V++  G ++  A+   W    IGR++ GLGVG  ++ AP+ ISE
Sbjct: 156 KLGDMYGRKIGLMTVVVIYSIGIIIQIASIDKWYQYFIGRIISGLGVGGITVLAPMLISE 215

Query: 145 ASPAKIRGALVCRLHQWFTHN------------------RWSISL-LPHQFGIYQVYRQS 185
            SP ++RG LV       T                    +W + L L   + I+ +   +
Sbjct: 216 VSPKQLRGTLVSCYQLMITFGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWSIFMIVGMT 275

Query: 186 -------------KEEEAKQILSKIYRPGE----VEEEMKAMHESIEAEKAEDGLIGHSL 228
                        K EEAK+ L++  +  E    V  EM+    SIEAE+        S 
Sbjct: 276 FVPESPRYLVEVGKIEEAKRSLARANKTTEDSPLVTLEMENYQSSIEAERLAGSA---SW 332

Query: 229 AQKLKGAWSNDVVRRGLYAGITVQVVQQIVGINTIMYYSPTIVQFAGIASNSTAFALSLV 288
            + + G     + RR L  G+ +Q +QQ+ G N   YY  TI Q  G+     +F  ++V
Sbjct: 333 GELVTG--KPQMFRRTL-MGMMIQSLQQLTGDNYFFYYGTTIFQAVGL---EDSFETAIV 386

Query: 289 TSGLNAVGTIVSMVLIDRFGRRKLMLISLIGIFVSLV 325
              +N V T  S+  +DRFGRR  +L   +G+    V
Sbjct: 387 LGVVNFVSTFFSLYTVDRFGRRNCLLWGCVGMICCYV 423


>KHT2_KLULA (P53387) Hexose transporter 2
          Length = 566

 Score =  107 bits (266), Expect = 7e-23
 Identities = 91/326 (27%), Positives = 151/326 (45%), Gaps = 54/326 (16%)

Query: 34  GGLLFGYDTGVISG----ASLYIRDEFEQVDKKPWLQET----IVSMASAGAIIGAAFGG 85
           GG +FG+DTG ISG         R   E+ D   +L       IVS+ + G  IG     
Sbjct: 72  GGFVFGWDTGTISGFVNQTDFIRRFGQEKADGSHYLSNVRTGLIVSIFNIGCAIGGIILS 131

Query: 86  YMNDKMGRKKTILMADVVFVAGALVMAAAPAPWV-IIIGRLLVGLGVGAASMTAPLYISE 144
            + D  GR+  +++  +++V G ++  A+   W    IGR++ GLGVG  S+ +P+ ISE
Sbjct: 132 KLGDMYGRRIGLMIVVLIYVVGIIIQIASIDKWYQYFIGRIISGLGVGGISVLSPMLISE 191

Query: 145 ASPAKIRGALV---------------CRLHQWFTHN---RWSISL-LPHQFGIYQV---- 181
            +P  IRG LV               C  +   T++   +W + L L   + I+ +    
Sbjct: 192 TAPKHIRGTLVSFYQLMITFGIFLGYCTNYGTKTYSNSVQWRVPLGLCFAWAIFMITGML 251

Query: 182 ---------YRQSKEEEAKQILSK----IYRPGEVEEEMKAMHESIEAEKAEDGLIGHSL 228
                      + + +EAK+ ++K     Y    V+ E+  +   +EAE+    L G + 
Sbjct: 252 FVPESPRFLVEKDRIDEAKRSIAKSNKVSYEDPAVQAEVDLICAGVEAER----LAGSAS 307

Query: 229 AQKLKGAWSNDVVRRGLYAGITVQVVQQIVGINTIMYYSPTIVQFAGIASNSTAFALSLV 288
            ++L    +   V + L  G+ +Q  QQ+ G N   YY  TI    G+     +F  S+V
Sbjct: 308 IKELFS--TKTKVFQRLIMGMLIQSFQQLTGNNYFFYYGTTIFNSVGM---DDSFETSIV 362

Query: 289 TSGLNAVGTIVSMVLIDRFGRRKLML 314
              +N   T V++ ++D+FGRRK +L
Sbjct: 363 LGIVNFASTFVAIYVVDKFGRRKCLL 388


>HXT7_YEAST (P39004) High-affinity hexose transporter HXT6
          Length = 570

 Score =  105 bits (261), Expect = 3e-22
 Identities = 90/342 (26%), Positives = 156/342 (45%), Gaps = 51/342 (14%)

Query: 34  GGLLFGYDTGVISG----ASLYIRDEFEQVDKKPWLQET----IVSMASAGAIIGAAFGG 85
           GG +FG+DTG ISG         R   +  D   +L +     IVS+ + G  IG     
Sbjct: 75  GGFVFGWDTGTISGFINQTDFIRRFGMKHKDGTNYLSKVRTGLIVSIFNIGCAIGGIILS 134

Query: 86  YMNDKMGRKKTILMADVVFVAGALVMAAAPAPWV-IIIGRLLVGLGVGAASMTAPLYISE 144
            + D  GRK  +++  V+++ G ++  A+   W    IGR++ GLGVG  ++ +P+ ISE
Sbjct: 135 KLGDMYGRKVGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISE 194

Query: 145 ASPAKIRGALVCRLHQWFTHN------------------RWSISL-LPHQFGIYQVYRQS 185
            SP  +RG LV       T                    +W + L L   + ++ +   +
Sbjct: 195 VSPKHLRGTLVSCYQLMITAGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMT 254

Query: 186 KEEEAKQILSKIYRPGEVEEEMKAMHESIEAEKAE-------DGLIGHSLAQKLKG--AW 236
              E+ + L+++   G++EE  +++  S +    +       + ++    A+KL G  +W
Sbjct: 255 FVPESPRYLAEV---GKIEEAKRSIAVSNKVAVDDPSVLAEVEAVLAGVEAEKLAGNASW 311

Query: 237 -----SNDVVRRGLYAGITVQVVQQIVGINTIMYYSPTIVQFAGIASNSTAFALSLVTSG 291
                S   V + L  G  +Q +QQ+ G N   YY  TI +  G+   S +F  S+V   
Sbjct: 312 GELFSSKTKVLQRLIMGAMIQSLQQLTGDNYFFYYGTTIFKAVGL---SDSFETSIVLGI 368

Query: 292 LNAVGTIVSMVLIDRFGRRKLML---ISLIGIFVSLVTLSVT 330
           +N   T V + +++R+GRR  +L    S+    V   ++ VT
Sbjct: 369 VNFASTFVGIYVVERYGRRTCLLWGAASMTACMVVYASVGVT 410


>HXT6_YEAST (P39003) High-affinity hexose transporter HXT6
          Length = 570

 Score =  105 bits (261), Expect = 3e-22
 Identities = 90/342 (26%), Positives = 156/342 (45%), Gaps = 51/342 (14%)

Query: 34  GGLLFGYDTGVISG----ASLYIRDEFEQVDKKPWLQET----IVSMASAGAIIGAAFGG 85
           GG +FG+DTG ISG         R   +  D   +L +     IVS+ + G  IG     
Sbjct: 75  GGFVFGWDTGTISGFINQTDFIRRFGMKHKDGTNYLSKVRTGLIVSIFNIGCAIGGIILS 134

Query: 86  YMNDKMGRKKTILMADVVFVAGALVMAAAPAPWV-IIIGRLLVGLGVGAASMTAPLYISE 144
            + D  GRK  +++  V+++ G ++  A+   W    IGR++ GLGVG  ++ +P+ ISE
Sbjct: 135 KLGDMYGRKVGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISE 194

Query: 145 ASPAKIRGALVCRLHQWFTHN------------------RWSISL-LPHQFGIYQVYRQS 185
            SP  +RG LV       T                    +W + L L   + ++ +   +
Sbjct: 195 VSPKHLRGTLVSCYQLMITAGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMT 254

Query: 186 KEEEAKQILSKIYRPGEVEEEMKAMHESIEAEKAE-------DGLIGHSLAQKLKG--AW 236
              E+ + L+++   G++EE  +++  S +    +       + ++    A+KL G  +W
Sbjct: 255 FVPESPRYLAEV---GKIEEAKRSIAVSNKVAVDDPSVLAEVEAVLAGVEAEKLAGNASW 311

Query: 237 -----SNDVVRRGLYAGITVQVVQQIVGINTIMYYSPTIVQFAGIASNSTAFALSLVTSG 291
                S   V + L  G  +Q +QQ+ G N   YY  TI +  G+   S +F  S+V   
Sbjct: 312 GELFSSKTKVLQRLIMGAMIQSLQQLTGDNYFFYYGTTIFKAVGL---SDSFETSIVLGI 368

Query: 292 LNAVGTIVSMVLIDRFGRRKLML---ISLIGIFVSLVTLSVT 330
           +N   T V + +++R+GRR  +L    S+    V   ++ VT
Sbjct: 369 VNFASTFVGIYVVERYGRRTCLLWGAASMTACMVVYASVGVT 410


>HXT4_YEAST (P32467) Low-affinity glucose transporter HXT4
           (Low-affinity glucose transporter LGT1)
          Length = 576

 Score =  104 bits (259), Expect = 5e-22
 Identities = 93/342 (27%), Positives = 160/342 (46%), Gaps = 51/342 (14%)

Query: 34  GGLLFGYDTGVISG----ASLYIRDEFEQVDKKPWLQET----IVSMASAGAIIGAAFGG 85
           GG +FG+DTG ISG         R   +  D   +L +     IVS+ + G  IG     
Sbjct: 81  GGFVFGWDTGTISGFVAQTDFIRRFGMKHHDGTYYLSKVRTGLIVSIFNIGCAIGGIILA 140

Query: 86  YMNDKMGRKKTILMADVVFVAGALVMAAAPAPWV-IIIGRLLVGLGVGAASMTAPLYISE 144
            + D  GRK  +++  V+++ G ++  A+   W    IGR++ GLGVG  ++ +P+ ISE
Sbjct: 141 KLGDMYGRKMGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISE 200

Query: 145 ASPAKIRGALV---------------CRLHQWFTHN---RWSISL-LPHQFGIYQVYRQS 185
            SP  IRG LV               C  +   T+    +W + L L   + ++ +   +
Sbjct: 201 VSPKHIRGTLVSCYQLMITLGIFLGYCTNYGTKTYTNSVQWRVPLGLGFAWALFMIGGMT 260

Query: 186 KEEEAKQILSKIYRPGEVEEEMK--AMHESIEAE----KAEDGLIGHSL-AQKLKG--AW 236
              E+ + L ++   G++EE  +  A+   + A+     AE  ++  ++ A+KL G  +W
Sbjct: 261 FVPESPRYLVEV---GKIEEAKRSIALSNKVSADDPAVMAEVEVVQATVEAEKLAGNASW 317

Query: 237 -----SNDVVRRGLYAGITVQVVQQIVGINTIMYYSPTIVQFAGIASNSTAFALSLVTSG 291
                +   V + L  G  +Q +QQ+ G N   YY  T+    G+     +F  S+V   
Sbjct: 318 GEIFSTKTKVFQRLIMGAMIQSLQQLTGDNYFFYYGTTVFTAVGL---EDSFETSIVLGI 374

Query: 292 LNAVGTIVSMVLIDRFGRRKLML---ISLIGIFVSLVTLSVT 330
           +N   T V + L++R+GRR+ +L    S+    V   ++ VT
Sbjct: 375 VNFASTFVGIFLVERYGRRRCLLWGAASMTACMVVFASVGVT 416


>GTR8_HUMAN (Q9NY64) Solute carrier family 2, facilitated glucose
           transporter, member 8 (Glucose transporter type 8)
           (Glucose transporter type X1)
          Length = 477

 Score =  103 bits (257), Expect = 8e-22
 Identities = 89/304 (29%), Positives = 141/304 (46%), Gaps = 29/304 (9%)

Query: 31  ALSGGLLFGYDTGVISGASLYIRDEFEQVDKKPWLQETIVSMASA----GAIIGAAFGGY 86
           A  G L FG+  G  S A   ++         P L +   S   A    GA  G   GG+
Sbjct: 33  AALGPLSFGFALGYSSPAIPSLQ---RAAPPAPRLDDAAASWFGAVVTLGAAAGGVLGGW 89

Query: 87  MNDKMGRKKTILMADVVFVAGALVMAAAPAPWVIIIGRLLVGLGVGAASMTAPLYISEAS 146
           + D+ GRK ++L+  V FVAG  V+ AA   W+++ GRLL GL  G AS+ AP+YISE +
Sbjct: 90  LVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWMLLGGRLLTGLACGVASLVAPVYISEIA 149

Query: 147 PAKIRGAL-------------VCRLHQWFTHNRWSISLLPHQFGIYQVYRQSKEEEAKQI 193
              +RG L             +  L  W    RW   L      +  +      E  + +
Sbjct: 150 YPAVRGLLGSCVQLMVVVGILLAYLAGWVLEWRWLAVLGCVPPSLMLLLMCFMPETPRFL 209

Query: 194 LSKIYRPGEVEEEMKAMHESIEAEKA-EDGLIGHSLAQKLKGAWSNDVVRRGLYAGITVQ 252
           L++  R    +E M A+     +E+  ED  IG   +  L        + +    G+++ 
Sbjct: 210 LTQHRR----QEAMAALRFLWGSEQGWEDPPIGAEQSFHL-ALLRQPGIYKPFIIGVSLM 264

Query: 253 VVQQIVGINTIMYYSPTIVQFAGIASNSTAFALSLVTSGLNAVGTIVSMVLIDRFGRRKL 312
             QQ+ G+N +M+Y+ TI + A    +S A   S+V   +  + T V+ +++DR GRR L
Sbjct: 265 AFQQLSGVNAVMFYAETIFEEAKFKDSSLA---SVVVGVIQVLFTAVAALIMDRAGRRLL 321

Query: 313 MLIS 316
           +++S
Sbjct: 322 LVLS 325


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.321    0.134    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,493,100
Number of Sequences: 164201
Number of extensions: 1816720
Number of successful extensions: 6271
Number of sequences better than 10.0: 257
Number of HSP's better than 10.0 without gapping: 200
Number of HSP's successfully gapped in prelim test: 57
Number of HSP's that attempted gapping in prelim test: 5610
Number of HSP's gapped (non-prelim): 480
length of query: 420
length of database: 59,974,054
effective HSP length: 113
effective length of query: 307
effective length of database: 41,419,341
effective search space: 12715737687
effective search space used: 12715737687
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)