BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC148485.4 - phase: 0
(449 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
PTB_HUMAN (P26599) Polypyrimidine tract-binding protein 1 (PTB) ... 141 4e-33
PTB_RAT (Q00438) Polypyrimidine tract-binding protein 1 (PTB) (H... 139 1e-32
PTB_PIG (Q29099) Polypyrimidine tract-binding protein 1 (PTB) (H... 139 2e-32
PTB_MOUSE (P17225) Polypyrimidine tract-binding protein 1 (PTB) ... 136 1e-31
ROD1_HUMAN (O95758) Regulator of differentiation 1 (Rod1) 127 8e-29
ROD1_RAT (Q9Z118) Regulator of differentiation 1 (Rod1) 125 2e-28
ROD1_MOUSE (Q8BHD7) Regulator of differentiation 1 (Rod1) 125 2e-28
ROL_HUMAN (P14866) Heterogeneous nuclear ribonucleoprotein L (hn... 65 5e-10
ROL_MOUSE (Q8R081) Heterogeneous nuclear ribonucleoprotein L (hn... 64 6e-10
FTSH_MYCLE (Q9CD58) Cell division protein ftsH homolog (EC 3.4.2... 44 8e-04
NUCL_XENLA (P20397) Nucleolin (Protein C23) 42 0.003
RN15_YEAST (P25299) mRNA 3'-end processing protein RNA15 42 0.004
RBS1_HUMAN (P29558) RNA binding motif, single-stranded interacti... 41 0.006
CAS3_RAT (Q8K3X0) Cancer susceptibility candidate gene 3 protein... 41 0.006
CAS3_MOUSE (Q8K3W3) Cancer susceptibility candidate gene 3 prote... 41 0.006
CAS3_HUMAN (O15234) Cancer susceptibility candidate gene 3 prote... 41 0.007
RPB1_DROME (P04052) DNA-directed RNA polymerase II largest subun... 40 0.012
RBS1_MOUSE (Q91W59) RNA binding motif, single-stranded interacti... 39 0.021
RU1A_HUMAN (P09012) U1 small nuclear ribonucleoprotein A (U1 snR... 38 0.047
PAB2_ARATH (P42731) Polyadenylate-binding protein 2 (Poly(A)-bin... 38 0.047
>PTB_HUMAN (P26599) Polypyrimidine tract-binding protein 1 (PTB)
(Heterogeneous nuclear ribonucleoprotein I) (hnRNP I)
(57 kDa RNA-binding protein PPTB-1)
Length = 531
Score = 141 bits (355), Expect = 4e-33
Identities = 113/389 (29%), Positives = 176/389 (45%), Gaps = 79/389 (20%)
Query: 3 SSKQQQQFRCTQIPSKVLHFRNLPWECSDEELADLCSPFGKVMSTKCNVGVNQNQAFVQF 62
S K + R +PS+V+H R LP + ++ E+ L PFGKV + G +NQAF++
Sbjct: 44 SKKFKGDSRSAGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKG--KNQAFIEM 101
Query: 63 AELNQAISMVSYYASSSEPAQVRGKTVYIQYSNRHHIVNSNSPGDIPGNVLLVTIEGVEA 122
A +MV+YY S + +RG+ +YIQ+SN + +SP L + V++
Sbjct: 102 NTEEAANTMVNYYTSVTPV--LRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQS 159
Query: 123 GD---------------------------------VSIDVIHLVFSAFGFVHKLATFEKT 149
G+ V++DV+H +FS FG V K+ TF K
Sbjct: 160 GNLALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKN 219
Query: 150 AGFQALIQYTDAETAASAKDSLDGRSIPRYLLPEHVGACNLRISYSAHRDLNIKFQSNRS 209
FQAL+QY D +A AK SLDG++I + C LRI +S LN+K+ +++S
Sbjct: 220 NQFQALLQYADPVSAQHAKLSLDGQNI-------YNACCTLRIDFSKLTSLNVKYNNDKS 272
Query: 210 RDYTNPMLPV--NQAAIDSALQPAIG---------------PDGKRKEHK---------- 242
RDYT P LP +Q ++D + A G P
Sbjct: 273 RDYTRPDLPSGDSQPSLDQTMAAAFGLSVPNVHGALAPLAIPSAAAAAAAAGRIAIPGLA 332
Query: 243 ---SNVLLATIENMQYAVPLDVLHSVFSAFGFVQKVAMFDKNGHTHALIQYPDLTIAAAA 299
++VLL + N + P L +F +G VQ+V + N +AL+Q D A A
Sbjct: 333 GAGNSVLLVSNLNPERVTP-QSLFILFGVYGDVQRVKIL-FNKKENALVQMADGNQAQLA 390
Query: 300 KETLEGHCIYDGGYCKLHLTYSRHTDLNV 328
L GH ++ + +T S+H ++ +
Sbjct: 391 MSHLNGHKLHGK---PIRITLSKHQNVQL 416
Score = 93.6 bits (231), Expect = 9e-19
Identities = 74/234 (31%), Positives = 105/234 (44%), Gaps = 26/234 (11%)
Query: 192 ISYSAHRDLNIKFQSNRSRDYT-----------NPMLPVNQAAIDSALQPAIGPDGKRKE 240
I +S H++L N++R N L + AA+D+ + A
Sbjct: 128 IQFSNHKELKTDSSPNQARAQAALQAVNSVQSGNLALAASAAAVDAGMAMA--------- 178
Query: 241 HKSNVLLATIENMQYAVPLDVLHSVFSAFGFVQKVAMFDKNGHTHALIQYPDLTIAAAAK 300
+S VL +EN+ Y V LDVLH +FS FG V K+ F KN AL+QY D A AK
Sbjct: 179 GQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAK 238
Query: 301 ETLEGHCIYDGGYCKLHLTYSRHTDLNVKAFSDKSRDYTVLDPSLHAAQAPAWQTTQAAT 360
+L+G IY+ C L + +S+ T LNVK +DKSRDYT D +Q QT AA
Sbjct: 239 LSLDGQNIYN-ACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPSLDQTMAAAF 297
Query: 361 MYS-----GSMGQMPSWDPNQQEVTQSYLSAPGTFPSGQAAPPFPGYSPAAVPP 409
S G++ + ++ PG +G + +P V P
Sbjct: 298 GLSVPNVHGALAPLAIPSAAAAAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTP 351
>PTB_RAT (Q00438) Polypyrimidine tract-binding protein 1 (PTB)
(Heterogeneous nuclear ribonucleoprotein I) (hnRNP I)
(Pyrimidine-binding protein) (PYBP)
Length = 555
Score = 139 bits (351), Expect = 1e-32
Identities = 90/269 (33%), Positives = 136/269 (50%), Gaps = 46/269 (17%)
Query: 3 SSKQQQQFRCTQIPSKVLHFRNLPWECSDEELADLCSPFGKVMSTKCNVGVNQNQAFVQF 62
S K + R T +PS+V+H R LP + ++ E+ L PFGKV + G +NQAF++
Sbjct: 43 SKKFKGDNRSTGVPSRVIHVRKLPSDVTEGEVISLGLPFGKVTNLLMLKG--KNQAFIEM 100
Query: 63 AELNQAISMVSYYASSSEPAQVRGKTVYIQYSNRHHIVNSNSPGDIPGNVLLVTIEGVEA 122
+ A +MV+YY S + +RG+ +YIQ+SN + +SP L + V++
Sbjct: 101 STEEAANTMVNYYTSVAPV--LRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQS 158
Query: 123 GD---------------------------------VSIDVIHLVFSAFGFVHKLATFEKT 149
G+ V++DV+H +FS FG V K+ TF K
Sbjct: 159 GNLALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKN 218
Query: 150 AGFQALIQYTDAETAASAKDSLDGRSIPRYLLPEHVGACNLRISYSAHRDLNIKFQSNRS 209
FQAL+QY D +A AK SLDG++I + C LRI +S LN+K+ +++S
Sbjct: 219 NQFQALLQYADPVSAQHAKLSLDGQNI-------YNACCTLRIDFSKLTSLNVKYNNDKS 271
Query: 210 RDYTNPMLPV--NQAAIDSALQPAIGPDG 236
RDYT P LP +Q ++D + A G G
Sbjct: 272 RDYTRPDLPSGDSQPSLDQTMAAAFGAPG 300
Score = 99.0 bits (245), Expect = 2e-20
Identities = 80/234 (34%), Positives = 109/234 (46%), Gaps = 29/234 (12%)
Query: 192 ISYSAHRDLNIKFQSNRSRDYT-----------NPMLPVNQAAIDSALQPAIGPDGKRKE 240
I +S H++L N++R N L + AA+D+ + A
Sbjct: 127 IQFSNHKELKTDSSPNQARAQAALQAVNSVQSGNLALAASAAAVDAGMAMA--------- 177
Query: 241 HKSNVLLATIENMQYAVPLDVLHSVFSAFGFVQKVAMFDKNGHTHALIQYPDLTIAAAAK 300
+S VL +EN+ Y V LDVLH +FS FG V K+ F KN AL+QY D A AK
Sbjct: 178 GQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAK 237
Query: 301 ETLEGHCIYDGGYCKLHLTYSRHTDLNVKAFSDKSRDYTVLDPSLHAAQAPAWQTTQAAT 360
+L+G IY+ C L + +S+ T LNVK +DKSRDYT D +Q QT AA
Sbjct: 238 LSLDGQNIYN-ACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPSLDQTMAAAF 296
Query: 361 MYSGSMGQMPSWDPNQQEVTQSYLSAPGTFPSGQAAPPFPG-YSPAAVPPAGAS 413
G M P S+L P +G + P G +P A+P A A+
Sbjct: 297 GAPGIMSASP-----YAGAVPSHLCHPSR--AGLSVPNVHGALAPLAIPSAAAA 343
>PTB_PIG (Q29099) Polypyrimidine tract-binding protein 1 (PTB)
(Heterogeneous nuclear ribonucleoprotein I) (hnRNP I)
Length = 557
Score = 139 bits (349), Expect = 2e-32
Identities = 90/269 (33%), Positives = 134/269 (49%), Gaps = 46/269 (17%)
Query: 3 SSKQQQQFRCTQIPSKVLHFRNLPWECSDEELADLCSPFGKVMSTKCNVGVNQNQAFVQF 62
S K + R +PS+V+H R LP + ++ E+ L PFGKV + G +NQAF++
Sbjct: 44 SKKFKGDNRSAGVPSRVIHIRKLPSDVTEGEVISLGLPFGKVTNLLMLKG--KNQAFIEM 101
Query: 63 AELNQAISMVSYYASSSEPAQVRGKTVYIQYSNRHHIVNSNSPGDIPGNVLLVTIEGVEA 122
A +MV+YY S + +RG+ +YIQ+SN + +SP L + V++
Sbjct: 102 NTEEAANTMVNYYTSVTPV--LRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQS 159
Query: 123 GD---------------------------------VSIDVIHLVFSAFGFVHKLATFEKT 149
G+ V++DV+H +FS FG V K+ TF K
Sbjct: 160 GNLALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKN 219
Query: 150 AGFQALIQYTDAETAASAKDSLDGRSIPRYLLPEHVGACNLRISYSAHRDLNIKFQSNRS 209
FQAL+QY D +A AK SLDG++I + C LRI +S LN+K+ +++S
Sbjct: 220 NQFQALLQYADPVSAQHAKLSLDGQNI-------YNACCTLRIDFSKLTSLNVKYNNDKS 272
Query: 210 RDYTNPMLPV--NQAAIDSALQPAIGPDG 236
RDYT P LP NQ ++D + A G G
Sbjct: 273 RDYTRPDLPSGDNQPSLDQTMAAAFGAPG 301
Score = 96.7 bits (239), Expect = 1e-19
Identities = 84/239 (35%), Positives = 108/239 (45%), Gaps = 40/239 (16%)
Query: 192 ISYSAHRDLNIKFQSNRSRDYT-----------NPMLPVNQAAIDSALQPAIGPDGKRKE 240
I +S H++L N++R N L + AA+D+ + A
Sbjct: 128 IQFSNHKELKTDSSPNQARAQAALQAVNSVQSGNLALAASAAAVDAGMAMA--------- 178
Query: 241 HKSNVLLATIENMQYAVPLDVLHSVFSAFGFVQKVAMFDKNGHTHALIQYPDLTIAAAAK 300
+S VL +EN+ Y V LDVLH +FS FG V K+ F KN AL+QY D A AK
Sbjct: 179 GQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAK 238
Query: 301 ETLEGHCIYDGGYCKLHLTYSRHTDLNVKAFSDKSRDYTVLDPSLHAAQAPAWQTTQAAT 360
+L+G IY+ C L + +S+ T LNVK +DKSRDYT D Q QT AA
Sbjct: 239 LSLDGQNIYN-ACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDNQPSLDQTMAAAF 297
Query: 361 MYSGSMGQMPSWDPNQQEVTQSYLSA--PGTFPSGQAA----PPFPG-YSPAAVPPAGA 412
G M P Y A P TF QAA P G +P A+P A A
Sbjct: 298 GAPGIMSASP------------YAGAGFPPTFAIPQAATVSVPNVHGALAPLAIPSAAA 344
>PTB_MOUSE (P17225) Polypyrimidine tract-binding protein 1 (PTB)
(Heterogeneous nuclear ribonucleoprotein I) (hnRNP I)
Length = 527
Score = 136 bits (343), Expect = 1e-31
Identities = 88/266 (33%), Positives = 134/266 (50%), Gaps = 46/266 (17%)
Query: 3 SSKQQQQFRCTQIPSKVLHFRNLPWECSDEELADLCSPFGKVMSTKCNVGVNQNQAFVQF 62
S K + R +PS+V+H R LP + ++ E+ L PFGKV + G +NQAF++
Sbjct: 43 SKKFKGDNRSAGVPSRVIHVRKLPSDVTEGEVISLGLPFGKVTNLLMLKG--KNQAFIEM 100
Query: 63 AELNQAISMVSYYASSSEPAQVRGKTVYIQYSNRHHIVNSNSPGDIPGNVLLVTIEGVEA 122
A +MV+YY S + +RG+ +YIQ+SN + +SP + L + V++
Sbjct: 101 NTEEAANTMVNYYTSVAPV--LRGQPIYIQFSNHKELKTDSSPNQVRAQAALQAVNSVQS 158
Query: 123 GD---------------------------------VSIDVIHLVFSAFGFVHKLATFEKT 149
G+ V++DV+H +FS FG V K+ TF K
Sbjct: 159 GNLALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKN 218
Query: 150 AGFQALIQYTDAETAASAKDSLDGRSIPRYLLPEHVGACNLRISYSAHRDLNIKFQSNRS 209
FQAL+QY D +A AK SLDG++I + C LRI +S LN+K+ +++S
Sbjct: 219 NQFQALLQYADPVSAQHAKLSLDGQNI-------YNACCTLRIDFSKLTSLNVKYNNDKS 271
Query: 210 RDYTNPMLPV--NQAAIDSALQPAIG 233
RDYT P LP +Q ++D + A G
Sbjct: 272 RDYTRPDLPSGDSQPSLDQTMAAAFG 297
Score = 92.4 bits (228), Expect = 2e-18
Identities = 64/170 (37%), Positives = 85/170 (49%), Gaps = 3/170 (1%)
Query: 192 ISYSAHRDLNIKFQSN--RSRDYTNPMLPVNQAAIDSALQPAIGPDGKRKEHKSNVLLAT 249
I +S H++L N R++ + V + A A G +S VL
Sbjct: 127 IQFSNHKELKTDSSPNQVRAQAALQAVNSVQSGNLALAASAAAVDAGMAMAGQSPVLRII 186
Query: 250 IENMQYAVPLDVLHSVFSAFGFVQKVAMFDKNGHTHALIQYPDLTIAAAAKETLEGHCIY 309
+EN+ Y V LDVLH +FS FG V K+ F KN AL+QY D A AK +L+G IY
Sbjct: 187 VENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAKLSLDGQNIY 246
Query: 310 DGGYCKLHLTYSRHTDLNVKAFSDKSRDYTVLDPSLHAAQAPAWQTTQAA 359
+ C L + +S+ T LNVK +DKSRDYT D +Q QT AA
Sbjct: 247 N-ACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPSLDQTMAAA 295
>ROD1_HUMAN (O95758) Regulator of differentiation 1 (Rod1)
Length = 521
Score = 127 bits (318), Expect = 8e-29
Identities = 84/268 (31%), Positives = 131/268 (48%), Gaps = 44/268 (16%)
Query: 2 SSSKQQQQFRCTQIPSKVLHFRNLPWECSDEELADLCSPFGKVMSTKCNVGVNQNQAFVQ 61
+ SK+ ++ R PS+VLH R +P + ++ E+ L PFGKV + G ++QAF++
Sbjct: 12 NDSKKFKRDRPPCSPSRVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLKG--KSQAFLE 69
Query: 62 FAELNQAISMVSYYASSSEPAQVRGKTVYIQYSNRHHIVNSNSPGDIPGNVLLVTIEGVE 121
A A++MV+YY + +R + VYIQYSN + N P L + V+
Sbjct: 70 MASEEAAVTMVNYYTPITP--HLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQ 127
Query: 122 AGD-------------------------------VSIDVIHLVFSAFGFVHKLATFEKTA 150
+G V+++V+H +FS FG V K+ TF K
Sbjct: 128 SGSLALSGGPSNEGTVLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNN 187
Query: 151 GFQALIQYTDAETAASAKDSLDGRSIPRYLLPEHVGACNLRISYSAHRDLNIKFQSNRSR 210
FQAL+QY D A AK +LDG++I + C LRI +S LN+K+ +++SR
Sbjct: 188 QFQALLQYADPVNAHYAKMALDGQNI-------YNACCTLRIDFSKLTSLNVKYNNDKSR 240
Query: 211 DYTNPMLPV--NQAAIDSALQPAIGPDG 236
D+T LP Q +++ + A G G
Sbjct: 241 DFTRLDLPTGDGQPSLEPPMAAAFGAPG 268
Score = 97.8 bits (242), Expect = 5e-20
Identities = 73/198 (36%), Positives = 101/198 (50%), Gaps = 13/198 (6%)
Query: 184 HVGACNLRISYSAHRDLNIKFQSNRSRDYTNPMLPVNQAAIDSALQPAIGP--DGKRKEH 241
H+ + + I YS HR+L N++R L A +L + GP +G
Sbjct: 89 HLRSQPVYIQYSNHRELKTDNLPNQAR--AQAALQAVSAVQSGSLALSGGPSNEGTVLPG 146
Query: 242 KSNVLLATIENMQYAVPLDVLHSVFSAFGFVQKVAMFDKNGHTHALIQYPDLTIAAAAKE 301
+S VL IEN+ Y V L+VLH +FS FG V K+ F KN AL+QY D A AK
Sbjct: 147 QSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHYAKM 206
Query: 302 TLEGHCIYDGGYCKLHLTYSRHTDLNVKAFSDKSRDYTVLD-------PSLHAAQAPAWQ 354
L+G IY+ C L + +S+ T LNVK +DKSRD+T LD PSL A A+
Sbjct: 207 ALDGQNIYN-ACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFG 265
Query: 355 TTQ-AATMYSGSMGQMPS 371
++ Y+G+ G P+
Sbjct: 266 APGIISSPYAGAAGFAPA 283
>ROD1_RAT (Q9Z118) Regulator of differentiation 1 (Rod1)
Length = 523
Score = 125 bits (315), Expect = 2e-28
Identities = 80/254 (31%), Positives = 125/254 (48%), Gaps = 44/254 (17%)
Query: 16 PSKVLHFRNLPWECSDEELADLCSPFGKVMSTKCNVGVNQNQAFVQFAELNQAISMVSYY 75
PS+VLH R +P + ++ E+ L PFGKV + G ++QAF++ A A++M++YY
Sbjct: 28 PSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKG--KSQAFLEMASEEAAVTMINYY 85
Query: 76 ASSSEPAQVRGKTVYIQYSNRHHIVNSNSPGDIPGNVLLVTIEGVEAGDVSI-------- 127
+ +R + VYIQYSN + N P L + V++G++S+
Sbjct: 86 TPVTP--HLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNLSLPGATSNEG 143
Query: 128 -----------------------DVIHLVFSAFGFVHKLATFEKTAGFQALIQYTDAETA 164
+V+H +FS FG V K+ TF K FQAL+QY D A
Sbjct: 144 TLLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNA 203
Query: 165 ASAKDSLDGRSIPRYLLPEHVGACNLRISYSAHRDLNIKFQSNRSRDYTNPMLPV--NQA 222
AK +LDG++I + C LRI +S LN+K+ +++SRD+T LP Q
Sbjct: 204 QYAKMALDGQNI-------YNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQP 256
Query: 223 AIDSALQPAIGPDG 236
+++ + A G G
Sbjct: 257 SLEPPMAAAFGAPG 270
Score = 100 bits (250), Expect = 6e-21
Identities = 91/265 (34%), Positives = 122/265 (45%), Gaps = 19/265 (7%)
Query: 184 HVGACNLRISYSAHRDLNIKFQSNRSRDYTNPMLPVNQAAIDSALQPAIGPDGKRKEHKS 243
H+ + + I YS HR+L N++R + + +L A +G +S
Sbjct: 91 HLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNLSLPGATSNEGTLLPGQS 150
Query: 244 NVLLATIENMQYAVPLDVLHSVFSAFGFVQKVAMFDKNGHTHALIQYPDLTIAAAAKETL 303
VL IEN+ Y V L+VLH +FS FG V K+ F KN AL+QY D A AK L
Sbjct: 151 PVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAQYAKMAL 210
Query: 304 EGHCIYDGGYCKLHLTYSRHTDLNVKAFSDKSRDYTVLDPSLHAAQAPAWQTTQAATMYS 363
+G IY+ C L + +S+ T LNVK +DKSRD+T LD Q P+ + AA
Sbjct: 211 DGQNIYN-ACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQ-PSLEPPMAAAF-- 266
Query: 364 GSMGQMPSWDPNQQEVTQSYLSAPGTFPSGQAAPPFPGYSPAAVPPAGASPHSHMPPSSF 423
G+ G M S Y A G F A P G S +AVP GA + S+
Sbjct: 267 GAPGIMSS----------PYAGAAG-FAPAIAFPQAAGLSVSAVP--GALGPLTLTSSAV 313
Query: 424 AG--AFPGSQPHYGWESRFRLNYNP 446
+G A PG+ G N NP
Sbjct: 314 SGRMAIPGASGIPGNSVLLVTNLNP 338
>ROD1_MOUSE (Q8BHD7) Regulator of differentiation 1 (Rod1)
Length = 523
Score = 125 bits (315), Expect = 2e-28
Identities = 80/254 (31%), Positives = 125/254 (48%), Gaps = 44/254 (17%)
Query: 16 PSKVLHFRNLPWECSDEELADLCSPFGKVMSTKCNVGVNQNQAFVQFAELNQAISMVSYY 75
PS+VLH R +P + ++ E+ L PFGKV + G ++QAF++ A A++M++YY
Sbjct: 28 PSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKG--KSQAFLEMASEEAAVTMINYY 85
Query: 76 ASSSEPAQVRGKTVYIQYSNRHHIVNSNSPGDIPGNVLLVTIEGVEAGDVSI-------- 127
+ +R + VYIQYSN + N P L + V++G++S+
Sbjct: 86 TPVTP--HLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNLSLPGATANEG 143
Query: 128 -----------------------DVIHLVFSAFGFVHKLATFEKTAGFQALIQYTDAETA 164
+V+H +FS FG V K+ TF K FQAL+QY D A
Sbjct: 144 TLLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNA 203
Query: 165 ASAKDSLDGRSIPRYLLPEHVGACNLRISYSAHRDLNIKFQSNRSRDYTNPMLPV--NQA 222
AK +LDG++I + C LRI +S LN+K+ +++SRD+T LP Q
Sbjct: 204 QYAKMALDGQNI-------YNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQP 256
Query: 223 AIDSALQPAIGPDG 236
+++ + A G G
Sbjct: 257 SLEPPMAAAFGAPG 270
Score = 100 bits (249), Expect = 8e-21
Identities = 91/265 (34%), Positives = 121/265 (45%), Gaps = 19/265 (7%)
Query: 184 HVGACNLRISYSAHRDLNIKFQSNRSRDYTNPMLPVNQAAIDSALQPAIGPDGKRKEHKS 243
H+ + + I YS HR+L N++R + + +L A +G +S
Sbjct: 91 HLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNLSLPGATANEGTLLPGQS 150
Query: 244 NVLLATIENMQYAVPLDVLHSVFSAFGFVQKVAMFDKNGHTHALIQYPDLTIAAAAKETL 303
VL IEN+ Y V L+VLH +FS FG V K+ F KN AL+QY D A AK L
Sbjct: 151 PVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAQYAKMAL 210
Query: 304 EGHCIYDGGYCKLHLTYSRHTDLNVKAFSDKSRDYTVLDPSLHAAQAPAWQTTQAATMYS 363
+G IY+ C L + +S+ T LNVK +DKSRD+T LD Q P+ + AA
Sbjct: 211 DGQNIYN-ACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQ-PSLEPPMAAAF-- 266
Query: 364 GSMGQMPSWDPNQQEVTQSYLSAPGTFPSGQAAPPFPGYSPAAVPPAGASPHSHMPPSSF 423
G+ G M S Y A G F A P G S AVP GA + S+
Sbjct: 267 GAPGIMSS----------PYAGAAG-FAPAIAFPQAAGLSVPAVP--GALGPLTLTSSAV 313
Query: 424 AG--AFPGSQPHYGWESRFRLNYNP 446
+G A PG+ G N NP
Sbjct: 314 SGRMAIPGASGMPGNSVLLVTNLNP 338
>ROL_HUMAN (P14866) Heterogeneous nuclear ribonucleoprotein L (hnRNP
L) (P/OKcl.14)
Length = 558
Score = 64.7 bits (156), Expect = 5e-10
Identities = 84/345 (24%), Positives = 134/345 (38%), Gaps = 69/345 (20%)
Query: 101 NSNSPGDIPGNVLLVTIEGVEAGDVSIDVIHLVFSAFGFVHKLATFEKTAGFQALIQYTD 160
N + P P + + V I G+ G V D++ + FG + + K QAL+++ D
Sbjct: 60 NYDDPHKTPASPV-VHIRGLIDGVVEADLVEAL-QEFGPISYVVVMPKKR--QALVEFED 115
Query: 161 AETAASAKDSLDGRSIPRYLLPEHVGACNLRISYSAHRDLNIKFQSNRSRDYTNPMLPVN 220
+GACN ++Y+A + I +P VN
Sbjct: 116 V-----------------------LGACNA-VNYAADNQIYIA---------GHPAF-VN 141
Query: 221 QAAIDSALQPAIGPDGKRKEHKSNVLLATIENMQYAVPLDVLHSVFSAFGFVQKVAMFDK 280
+ +P D + ++VLL TI N Y++ DVL+++ + G VQ++ +F K
Sbjct: 142 YSTSQKISRPGDSDDSRSV---NSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRK 198
Query: 281 NGHTHALIQYPDLTIAAAAKETLEGHCIYDGGYCKLHLTYSRHTDLNVKAFSDKSRDYTV 340
NG A++++ + A AK +L G IY G C L + Y++ T LNV + DYT
Sbjct: 199 NG-VQAMVEFDSVQSAQRAKASLNGADIY-SGCCTLKIEYAKPTRLNVFKNDQDTWDYT- 255
Query: 341 LDPSLHAAQAPAWQTTQAATM----------YSGSMGQMPSWDPNQQEVTQSYLSAPGTF 390
+P+L P + Y G G S + Y P +
Sbjct: 256 -NPNLSGQGDPGSNPNKRQRQPPLLGDHPAEYGGPHGGYHS-----HYHDEGYGPPPPHY 309
Query: 391 PSGQAAPPFPGYSPAAVPPAGASPHSHMPPSSFAGAFPGSQPHYG 435
+ PP G+ P + H PP P P YG
Sbjct: 310 EGRRMGPPVGGHRRG--PSRYGPQYGHPPP-------PPPPPEYG 345
Score = 32.3 bits (72), Expect = 2.6
Identities = 15/40 (37%), Positives = 21/40 (52%)
Query: 3 SSKQQQQFRCTQIPSKVLHFRNLPWECSDEELADLCSPFG 42
S+ +Q Q PS VLHF N P E ++E ++C G
Sbjct: 455 STPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELG 494
>ROL_MOUSE (Q8R081) Heterogeneous nuclear ribonucleoprotein L (hnRNP
L)
Length = 555
Score = 64.3 bits (155), Expect = 6e-10
Identities = 84/345 (24%), Positives = 134/345 (38%), Gaps = 69/345 (20%)
Query: 101 NSNSPGDIPGNVLLVTIEGVEAGDVSIDVIHLVFSAFGFVHKLATFEKTAGFQALIQYTD 160
N + P P + + V I G+ G V D++ + FG + + K QAL+++ D
Sbjct: 57 NYDDPHKTPASPV-VHIRGLIDGVVEADLVEAL-QEFGPISYVVVMPKKR--QALVEFED 112
Query: 161 AETAASAKDSLDGRSIPRYLLPEHVGACNLRISYSAHRDLNIKFQSNRSRDYTNPMLPVN 220
+GACN ++Y+A + I +P VN
Sbjct: 113 V-----------------------LGACNA-VNYAADNQIYIA---------GHPAF-VN 138
Query: 221 QAAIDSALQPAIGPDGKRKEHKSNVLLATIENMQYAVPLDVLHSVFSAFGFVQKVAMFDK 280
+ +P D + ++VLL TI N Y++ DVL+++ + G VQ++ +F K
Sbjct: 139 YSTSQKISRPGDSDDSRSV---NSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRK 195
Query: 281 NGHTHALIQYPDLTIAAAAKETLEGHCIYDGGYCKLHLTYSRHTDLNVKAFSDKSRDYTV 340
NG A++++ + A AK +L G IY G C L + Y++ T LNV + DYT
Sbjct: 196 NG-VQAMVEFDSVQSAQRAKASLNGADIY-SGCCTLKIEYAKPTRLNVFKNDQDTWDYT- 252
Query: 341 LDPSLHAAQAPAWQTTQAATM----------YSGSMGQMPSWDPNQQEVTQSYLSAPGTF 390
+P+L P + Y G G S + Y P +
Sbjct: 253 -NPNLSGQGDPGSNPNKRQRQPPLLGDHPAEYGGPHGGYHS-----HYHDEGYGPPPPHY 306
Query: 391 PSGQAAPPFPGYSPAAVPPAGASPHSHMPPSSFAGAFPGSQPHYG 435
+ PP G+ P + H PP P P YG
Sbjct: 307 EGRRMGPPVGGHRRG--PSRYGPQYGHPPP-------PPPPPDYG 342
Score = 33.1 bits (74), Expect = 1.5
Identities = 17/49 (34%), Positives = 23/49 (46%)
Query: 3 SSKQQQQFRCTQIPSKVLHFRNLPWECSDEELADLCSPFGKVMSTKCNV 51
S+ +Q Q PS VLHF N P E ++E ++C G T V
Sbjct: 452 STPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPTSVKV 500
>FTSH_MYCLE (Q9CD58) Cell division protein ftsH homolog (EC
3.4.24.-)
Length = 787
Score = 43.9 bits (102), Expect = 8e-04
Identities = 32/110 (29%), Positives = 45/110 (40%), Gaps = 17/110 (15%)
Query: 333 DKSRDYTVLDPSLHAA---QAPAWQTTQAATMYSGSMGQMPSWDPNQQEVTQS-YLSAPG 388
D+ R + P A AP W Q W P +Q+ +QS Y P
Sbjct: 688 DRQRQHGPTQPDYGAPPGWHAPGWPPQQPPDY----------WYPPEQQPSQSPYWPQPA 737
Query: 389 TFPSGQAAPPFPGY--SPAAVPPAGASPHSHMPPSSF-AGAFPGSQPHYG 435
GQA PP+P Y P+ PP ++P + PP+ G P + P +G
Sbjct: 738 PSYPGQAPPPYPSYPPCPSYPPPGQSAPDAGKPPAQLDEGVSPSNPPAHG 787
>NUCL_XENLA (P20397) Nucleolin (Protein C23)
Length = 650
Score = 42.0 bits (97), Expect = 0.003
Identities = 38/166 (22%), Positives = 75/166 (44%), Gaps = 14/166 (8%)
Query: 17 SKVLHFRNLPWECSDEELADLCSPFGKVMSTKCNVGVNQNQAFVQFAELNQAISMVSYYA 76
S+ L +N+P+ + EEL ++ + G N+ A+V+F+ ++A +
Sbjct: 323 SRTLFVKNIPYSTTVEELQEIFENAKDIRIPTGKDGSNKGIAYVEFSNEDEANKAL---- 378
Query: 77 SSSEPAQVRGKTVYIQYSNRHHIVNSNSPG-DIPGNVLLVTIEGVEAGDVSIDVIHLVFS 135
+ A++ G+++++ ++ + N G + VL+V A + D + VF
Sbjct: 379 EEKQGAEIEGRSIFVDFTGEKSQNSGNKKGPEGDSKVLVVNNLSYSATE---DSLREVFE 435
Query: 136 AFGFVHKLATFEKTAGFQALIQYTDAETAASAKDS-----LDGRSI 176
+ + GF A I+++ AE A A DS ++GRSI
Sbjct: 436 KATSIRIPQNQGRAKGF-AFIEFSSAEDAKDAMDSCNNTEIEGRSI 480
>RN15_YEAST (P25299) mRNA 3'-end processing protein RNA15
Length = 296
Score = 41.6 bits (96), Expect = 0.004
Identities = 19/61 (31%), Positives = 38/61 (62%), Gaps = 4/61 (6%)
Query: 16 PSKVLHFRNLPWECSDEELADLCSPFGKVMSTKC----NVGVNQNQAFVQFAELNQAISM 71
PS+V++ ++P++ ++E++ DLCS G V++ K G ++ AF++F +L + S
Sbjct: 16 PSRVVYLGSIPYDQTEEQILDLCSNVGPVINLKMMFDPQTGRSKGYAFIEFRDLESSASA 75
Query: 72 V 72
V
Sbjct: 76 V 76
>RBS1_HUMAN (P29558) RNA binding motif, single-stranded interacting
protein 1 (Single-stranded DNA-binding protein MSSP-1)
(Suppressor of CDC2 with RNA binding motif 2)
Length = 406
Score = 41.2 bits (95), Expect = 0.006
Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 4/75 (5%)
Query: 14 QIPSKVLHFRNLPWECSDEELADLCSPFGKVMSTKCNVGVNQNQ----AFVQFAELNQAI 69
Q+ L+ R LP +D++L LC P+GK++STK + N+ FV F A
Sbjct: 58 QLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQ 117
Query: 70 SMVSYYASSSEPAQV 84
VS +S AQ+
Sbjct: 118 KAVSALKASGVQAQM 132
Score = 32.7 bits (73), Expect = 2.0
Identities = 17/77 (22%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Query: 2 SSSKQQQQFRCTQIPSKVLHFRNLPWECSDEELADLCSPFGKVMSTKC---NVGVNQNQA 58
+S Q Q + + L+ NLP ++EL ++ PFG+V+ST+ + G ++
Sbjct: 125 ASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRDSSGTSRGVG 184
Query: 59 FVQFAELNQAISMVSYY 75
F + + +++ ++
Sbjct: 185 FARMESTEKCEAVIGHF 201
>CAS3_RAT (Q8K3X0) Cancer susceptibility candidate gene 3 protein
(Metastatic lymph node protein 51) (MLN 51 protein)
(Barentsz protein) (Btz)
Length = 699
Score = 41.2 bits (95), Expect = 0.006
Identities = 28/82 (34%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 343 PSLHAAQAPAWQTTQAATMYSGSMGQMPSWDPNQQEVTQSYLSAPGTFPSGQAAPPFPGY 402
P LH Q+PA +Y + P P QQ + +Y SAPG G P +P Y
Sbjct: 579 PGLHPHQSPAPLPNPG--LYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGN--PSYP-Y 633
Query: 403 SPAAVPPAGASPHSHMPPSSFA 424
+P A+PP P H+ P++ A
Sbjct: 634 APGALPP---PPPPHLYPNTQA 652
>CAS3_MOUSE (Q8K3W3) Cancer susceptibility candidate gene 3 protein
(Metastatic lymph node protein 51) (MLN 51 protein)
(Barentsz protein) (Btz)
Length = 697
Score = 41.2 bits (95), Expect = 0.006
Identities = 27/85 (31%), Positives = 38/85 (43%), Gaps = 7/85 (8%)
Query: 343 PSLHAAQAPAWQTTQAATMYSGSMGQMPSWDPNQQEVTQSYLSAPGTFPSGQAAPPFPGY 402
P LH Q+P +Y + P P QQ + +Y SAPG G P +P Y
Sbjct: 578 PGLHPHQSPGPLPNPG--LYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGN--PNYP-Y 632
Query: 403 SPAAVPPAGAS--PHSHMPPSSFAG 425
+P A+PP P++ PP + G
Sbjct: 633 APGALPPPPPHLYPNTQAPPQVYGG 657
>CAS3_HUMAN (O15234) Cancer susceptibility candidate gene 3 protein
(Metastatic lymph node protein 51) (MLN 51 protein)
(Barentsz protein) (Btz)
Length = 703
Score = 40.8 bits (94), Expect = 0.007
Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 8/82 (9%)
Query: 343 PSLHAAQAPAWQTTQAATMYSGSMGQMPSWDPNQQEVTQSYLSAPGTFPSGQAAPPFPGY 402
P LH Q PA +Y + P P QQ + +Y SAPG G P +P Y
Sbjct: 583 PGLHPHQTPAPLPNPG--LYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGN--PSYP-Y 637
Query: 403 SPAAVPPAGASPHSHMPPSSFA 424
+P A+PP P H+ P++ A
Sbjct: 638 APGALPP---PPPPHLYPNTQA 656
>RPB1_DROME (P04052) DNA-directed RNA polymerase II largest subunit
(EC 2.7.7.6)
Length = 1887
Score = 40.0 bits (92), Expect = 0.012
Identities = 33/105 (31%), Positives = 47/105 (44%), Gaps = 6/105 (5%)
Query: 331 FSDKSRDYTVLDPSLHAAQAPAWQTTQAATMYSGSMGQMPSWDPNQQEVTQSYL-SAPGT 389
+S S Y+ PS ++ +P++ T YS + PN VT SY ++P
Sbjct: 1678 YSPNSPSYSPTSPS-YSPSSPSYSPTSPC--YSPTSPSYSPTSPNYTPVTPSYSPTSPNY 1734
Query: 390 FPSGQAAPPFPGYSPAAVPPAGASPHSHMPPSSFAGAFPGSQPHY 434
S Q +P P YS V + SP ++ PPS PGS P Y
Sbjct: 1735 SASPQYSPASPAYSQTGVKYSPTSP-TYSPPSPSYDGSPGS-PQY 1777
>RBS1_MOUSE (Q91W59) RNA binding motif, single-stranded interacting
protein 1 (Single-stranded DNA-binding protein MSSP-1)
Length = 403
Score = 39.3 bits (90), Expect = 0.021
Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 4/75 (5%)
Query: 14 QIPSKVLHFRNLPWECSDEELADLCSPFGKVMSTKCNVGVNQNQ----AFVQFAELNQAI 69
Q+ L+ R LP +D++L LC P+GK++STK + N+ FV F A
Sbjct: 58 QLSKTNLYIRGLPPNTTDQDLVKLCQPYGKIVSTKAILDKATNKCKGYGFVDFDSPAAAQ 117
Query: 70 SMVSYYASSSEPAQV 84
VS ++ AQ+
Sbjct: 118 KAVSALKANGVQAQM 132
Score = 32.3 bits (72), Expect = 2.6
Identities = 14/59 (23%), Positives = 32/59 (53%), Gaps = 3/59 (5%)
Query: 20 LHFRNLPWECSDEELADLCSPFGKVMSTKC---NVGVNQNQAFVQFAELNQAISMVSYY 75
L+ NLP ++EL ++ PFG+V+ST+ + G ++ F + + +++ ++
Sbjct: 143 LYISNLPLSMDEQELENMLKPFGQVISTRVLRDSSGASRGVGFARMESTEKCEAVIGHF 201
>RU1A_HUMAN (P09012) U1 small nuclear ribonucleoprotein A (U1 snRNP
protein A) (U1A protein) (U1-A)
Length = 281
Score = 38.1 bits (87), Expect = 0.047
Identities = 42/181 (23%), Positives = 70/181 (38%), Gaps = 20/181 (11%)
Query: 262 LHSVFSAFGFVQKVAMFDK-NGHTHALIQYPDLTIAAAAKETLEGHCIYDGGYCKLHLTY 320
L+++FS FG + + + A + + +++ A A +++G YD + + Y
Sbjct: 29 LYAIFSQFGQILDILVSRSLKMRGQAFVIFKEVSSATNALRSMQGFPFYDK---PMRIQY 85
Query: 321 SRHTDLNVKA-----FSDKSRDYTVLDPSLHAAQAP--AWQTTQAATMYSGSMGQMPSWD 373
++ TD ++ A F ++ R P A A Q A + G +P
Sbjct: 86 AK-TDSDIIAKMKGTFVERDRKREKRKPKSQETPATKKAVQGGGATPVVGAVQGPVPGMP 144
Query: 374 PNQQ--EVTQSYLSAPGTFPSGQAAPPFPGYSPAAVPPAGASPHSHMPPSSFAGAFPGSQ 431
P Q + P P PP PG +P +PP P MP G P +Q
Sbjct: 145 PMTQAPRIMHHMPGQPPYMPPPGMIPP-PGLAPGQIPPGAMPPQQLMP-----GQMPPAQ 198
Query: 432 P 432
P
Sbjct: 199 P 199
>PAB2_ARATH (P42731) Polyadenylate-binding protein 2
(Poly(A)-binding protein 2) (PABP 2)
Length = 629
Score = 38.1 bits (87), Expect = 0.047
Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 6/74 (8%)
Query: 17 SKVLHFRNLPWECSDEELADLCSPFGKVMSTKC---NVGVNQNQAFVQFA---ELNQAIS 70
S L+ +NL SDE+L ++ SPFG V S+K G ++ FV FA E +A+S
Sbjct: 317 SSNLYVKNLDPSISDEKLKEIFSPFGTVTSSKVMRDPNGTSKGSGFVAFATPEEATEAMS 376
Query: 71 MVSYYASSSEPAQV 84
+S S+P V
Sbjct: 377 QLSGKMIESKPLYV 390
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.317 0.131 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,833,918
Number of Sequences: 164201
Number of extensions: 2377953
Number of successful extensions: 9034
Number of sequences better than 10.0: 197
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 164
Number of HSP's that attempted gapping in prelim test: 8282
Number of HSP's gapped (non-prelim): 674
length of query: 449
length of database: 59,974,054
effective HSP length: 113
effective length of query: 336
effective length of database: 41,419,341
effective search space: 13916898576
effective search space used: 13916898576
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Medicago: description of AC148485.4