BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC148484.9 + phase: 0
(502 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
RU17_ARATH (Q42404) U1 small nuclear ribonucleoprotein 70 kDa (U... 535 e-151
RU17_XENLA (P09406) U1 small nuclear ribonucleoprotein 70 kDa (U... 321 2e-87
RU17_HUMAN (P08621) U1 small nuclear ribonucleoprotein 70 kDa (U... 318 2e-86
RU17_DROME (P17133) U1 small nuclear ribonucleoprotein 70 kDa (U... 283 6e-76
RU17_MOUSE (Q62376) U1 small nuclear ribonucleoprotein 70 kDa (U... 278 2e-74
SFRC_HUMAN (Q8WXA9) Splicing factor, arginine/serine-rich 12 (Se... 125 2e-28
SFRC_MOUSE (Q8BZX4) Splicing factor, arginine/serine-rich 12 (Se... 122 3e-27
SFRC_RAT (Q9JKL7) Splicing factor, arginine/serine-rich 12 (Seri... 121 5e-27
RU17_YEAST (Q00916) U1 small nuclear ribonucleoprotein 70 kDa ho... 119 2e-26
CTF8_HUMAN (Q96D72) Protein C20orf158 105 2e-22
SFR4_HUMAN (Q08170) Splicing factor, arginine/serine-rich 4 (Pre... 100 1e-20
T2_MOUSE (Q06666) Octapeptide-repeat protein T2 98 6e-20
NLFE_MOUSE (P19426) Negative elongation factor E (NELF-E) (RD pr... 97 1e-19
SFR4_MOUSE (Q8VE97) Splicing factor, arginine/serine-rich 4 94 1e-18
PPIG_RAT (O55035) Peptidyl-prolyl cis-trans isomerase G (EC 5.2.... 94 1e-18
NLFE_HUMAN (P18615) Negative elongation factor E (NELF-E) (RD pr... 93 2e-18
PPIG_HUMAN (Q13427) Peptidyl-prolyl cis-trans isomerase G (EC 5.... 89 2e-17
SRCH_RABIT (P16230) Sarcoplasmic reticulum histidine-rich calciu... 89 3e-17
SFR6_HUMAN (Q13247) Splicing factor, arginine/serine-rich 6 (Pre... 88 5e-17
RMX2_MOUSE (Q8R0F5) RNA binding motif protein, X-linked 2 87 8e-17
>RU17_ARATH (Q42404) U1 small nuclear ribonucleoprotein 70 kDa (U1
snRNP 70 kDa) (snRNP70) (U1-70K)
Length = 427
Score = 535 bits (1377), Expect = e-151
Identities = 299/505 (59%), Positives = 353/505 (69%), Gaps = 92/505 (18%)
Query: 3 DPLLRNQNAAVQARTKAQNRANVLQLKLIGQSHPTGLTANLLKLFEPRPPLEYKPPPEKR 62
DP LRN NAAVQAR K QNRANVLQLKL+GQSHPTGLT NLLKLFEPRPPLEYKPPPEKR
Sbjct: 6 DPFLRNPNAAVQARAKVQNRANVLQLKLMGQSHPTGLTNNLLKLFEPRPPLEYKPPPEKR 65
Query: 63 KCPPLTGMAQFVSKFAEPGEPEYSPPVPVVETPAERRARVHKLRLEKGAAKAAEELEKYD 122
KCPP TGMAQFVS FAEPG+PEY+PP P VE P+++R R+HKLRLEKG KAAE+L+KYD
Sbjct: 66 KCPPYTGMAQFVSNFAEPGDPEYAPPKPEVELPSQKRERIHKLRLEKGVEKAAEDLKKYD 125
Query: 123 PHNDPNISGDPYKTLFVARLSYETTESRIKREFESYGAIKRVRLVTDAESNKPRGYAFIE 182
P+NDPN +GDPYKTLFV+RL+YE++ES+IKREFESYG IKRV LVTD +NKP+GYAFIE
Sbjct: 126 PNNDPNATGDPYKTLFVSRLNYESSESKIKREFESYGPIKRVHLVTDQLTNKPKGYAFIE 185
Query: 183 YLHTRDMKAAYKQADGRKIEGRRVLVDVERGRTVPNWRPRRLGGGLGTTRVGGDEVNQRH 242
Y+HTRDMKAAYKQADG+KI+GRRVLVDVERGRTVPNWRPRRLGGGLGT+RVGG E
Sbjct: 186 YMHTRDMKAAYKQADGQKIDGRRVLVDVERGRTVPNWRPRRLGGGLGTSRVGGGE---EI 242
Query: 243 SGREQQQSGPSRSEEP-RVREERHADRDREKSRERGKDRDRERERSRERSSDKARDRDRD 301
G +Q Q S+SEEP R REE REKSRE+GK+R+R RE S E+ +++RDR
Sbjct: 243 VGEQQPQGRTSQSEEPSRPREE------REKSREKGKERERSRELSHEQPRERSRDRP-- 294
Query: 302 HREDRHHRDRD---RNRDRDRGKERDRERDRGRDRERGRDRDRGRERDRDRERDHERDVE 358
RED+HHRDRD R+RDRD ++RDR RDRG DR+R RDRDRGR+R RDH+R
Sbjct: 295 -REDKHHRDRDQGGRDRDRDSRRDRDRTRDRG-DRDR-RDRDRGRDR---TSRDHDR--- 345
Query: 359 HDRYREKDKDYEVGETDR---GRSHDRGADYDHVESKHEKEPHGEIERDYEPDDHHGRYK 415
DR R+K++DYE GE + GRS +R A+Y EP++ G Y+
Sbjct: 346 -DRSRKKERDYEGGEYEHEGGGRSRERDAEYRG-----------------EPEETRGYYE 387
Query: 416 EPGHGHRHADPEHDPDHYNHYEHQRGRGQYDEGDDRGDYNQYPDHAKMEDDHHTERAKSK 475
D + D D Y+H +YD+ + EDD ER
Sbjct: 388 ---------DDQGDTDRYSH--------RYDKME--------------EDDFRYER---- 412
Query: 476 SRDRDRNRDKDHDYHRSERSHSREY 500
+Y RS+RS SREY
Sbjct: 413 ------------EYKRSKRSESREY 425
Score = 43.1 bits (100), Expect = 0.002
Identities = 44/193 (22%), Positives = 66/193 (33%), Gaps = 49/193 (25%)
Query: 310 DRDRNRDRDRGKERDRERDRGRDRERGRDRDRGRERDRDRERDHERDVEHDRYREKDKDY 369
D +R R + R G R G + G ++ + R E REK ++
Sbjct: 212 DVERGRTVPNWRPRRLGGGLGTSRVGGGEEIVGEQQPQGRTSQSEEPSRPREEREKSRE- 270
Query: 370 EVGETDRGRSHDRGADYDHVESKHEKEPHGEIERDYEPDDHHGRYKEPGHGHRHADPEHD 429
+G+ +R + H + + E RD +D H R ++ G R D D
Sbjct: 271 ------KGKERERSRELSHEQPR-------ERSRDRPREDKHHRDRDQGGRDRDRDSRRD 317
Query: 430 PDHYNHYEHQRGRGQYDEGDDRGDYNQYPDHAKMEDDHHTERAKSKSRDRDRNRDKDHDY 489
D DRGD ++ RDRDR RD+
Sbjct: 318 RDRTR---------------DRGDRDR--------------------RDRDRGRDRTSRD 342
Query: 490 HRSERSHSREYDY 502
H +RS +E DY
Sbjct: 343 HDRDRSRKKERDY 355
>RU17_XENLA (P09406) U1 small nuclear ribonucleoprotein 70 kDa (U1
snRNP 70 kDa) (snRNP70) (U1-70K)
Length = 471
Score = 321 bits (823), Expect = 2e-87
Identities = 209/475 (44%), Positives = 267/475 (56%), Gaps = 69/475 (14%)
Query: 39 LTANLLKLFEPRPPLEYKPP-----PEKRKCPPLTGMAQFVSKFAEPGEPEYSPPVPVVE 93
L NLL LF PR P+ Y PP EK P G+A ++ +F +P + +PP E
Sbjct: 5 LPPNLLALFAPRDPVPYLPPLDKLPHEKHHNQPYCGIAPYIREFEDPRD---APPPTRAE 61
Query: 94 TPAERRARVHKLRLEKGAAKAAEELEKYDPHNDPNISGDPYKTLFVARLSYETTESRIKR 153
T ER R + ++E+ EL+ +DPHND N GD +KTLFVAR++Y+TTES+++R
Sbjct: 62 TREERMERKRREKIERRQQDVENELKIWDPHNDQNAQGDAFKTLFVARVNYDTTESKLRR 121
Query: 154 EFESYGAIKRVRLVTDAESN---KPRGYAFIEYLHTRDMKAAYKQADGRKIEGRRVLVDV 210
EFE YG IKR+ +V + S KPRGYAFIEY H RDM +AYK ADG+KI+GRRVLVDV
Sbjct: 122 EFEVYGPIKRIHIVYNKGSEGSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDV 181
Query: 211 ERGRTVPNWRPRRLGGGLGTTRVGGDEVNQRHSGREQQQSGPSRSEEPRVREERHADRDR 270
ERGRTV WRPRRLGGGLG TR GG +VN RHSGR+ R E R DR R
Sbjct: 182 ERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERDRE------RERDR-R 234
Query: 271 EKSRERGKD-RDRERERSRERSSDKARDRDRDHREDRHHRDRDRNRDRDRGKERDRERDR 329
E+SRER K+ R+R R RSRER K+R R+++ R+ R R++++D+D+ K++D +DR
Sbjct: 235 ERSREREKEPRERRRSRSRERRR-KSRSREKEERK----RTREKSKDKDKEKDKDN-KDR 288
Query: 330 GRDRERGRDRDRGRERDRDRERDHERDVEHDRYREKDKDYEVGETDRGRSHDR---GADY 386
R R R R R+R RERDRDRE+ ER + EV E D D
Sbjct: 289 DRKR-RSRSRERKRERDRDREKKEER-----------VEAEVPEADDAPQDDAQIGDLGI 336
Query: 387 DHVESKHEKEPHGEIERDYEPDDHHGRYKEPGHGHRHADPEHDPDHYNHYEHQRGRGQYD 446
D +E K E E E+ E D R +E G R D + D D R R D
Sbjct: 337 DGIELKQEPE-----EKSRERDRERDRDREKGEKDRDKDRDRDRD--------RRRSHRD 383
Query: 447 EGDDRGDYNQYPDHAKMEDDHHTERAKSKSRDRDRNRDKDH--DYHRSERSHSRE 499
DR E D +R + + RDRDR RDKDH + R +RS RE
Sbjct: 384 R--DR------------EKDRDRDRDRRRDRDRDRERDKDHKRERDRGDRSEKRE 424
Score = 80.9 bits (198), Expect = 7e-15
Identities = 45/117 (38%), Positives = 67/117 (56%), Gaps = 6/117 (5%)
Query: 251 GPSRSEEPRVREERHADRDREKSRERG-KDRDRERERSRERSSDKARDRDRDHREDRHHR 309
G +EP + R DR+R++ RE+G KDRD++R+R R+R + RDRD +DR R
Sbjct: 338 GIELKQEPE-EKSRERDRERDRDREKGEKDRDKDRDRDRDR---RRSHRDRDREKDRD-R 392
Query: 310 DRDRNRDRDRGKERDRERDRGRDRERGRDRDRGRERDRDRERDHERDVEHDRYREKD 366
DRDR RDRDR +ERD++ R RDR ++ R D + + D Y +++
Sbjct: 393 DRDRRRDRDRDRERDKDHKRERDRGDRSEKREERVPDNGMVMEQAEETSQDMYLDQE 449
Score = 77.8 bits (190), Expect = 6e-14
Identities = 50/124 (40%), Positives = 67/124 (53%), Gaps = 15/124 (12%)
Query: 256 EEPRVREERHADRDREKS---RERGKDRDRERERS-RERSSDKARDRDRDHREDRHHRDR 311
EE +R DRDREK R++ +DRDR+R RS R+R +K RDRDRD R RDR
Sbjct: 346 EEKSRERDRERDRDREKGEKDRDKDRDRDRDRRRSHRDRDREKDRDRDRDRR-----RDR 400
Query: 312 DRNRDRDRGKERDRER-DRGRDRE-----RGRDRDRGRERDRDRERDHERDVEHDRYREK 365
DR+R+RD+ +R+R+R DR RE G ++ E +D D E D Y
Sbjct: 401 DRDRERDKDHKRERDRGDRSEKREERVPDNGMVMEQAEETSQDMYLDQESMQSGDGYLST 460
Query: 366 DKDY 369
+ Y
Sbjct: 461 ENGY 464
>RU17_HUMAN (P08621) U1 small nuclear ribonucleoprotein 70 kDa (U1
snRNP 70 kDa) (snRNP70) (U1-70K)
Length = 437
Score = 318 bits (815), Expect = 2e-86
Identities = 181/398 (45%), Positives = 240/398 (59%), Gaps = 61/398 (15%)
Query: 39 LTANLLKLFEPRPPLEYKPP-----PEKRKCPPLTGMAQFVSKFAEPGEPEYSPPVPVVE 93
L NLL LF PR P+ Y PP EK P G+A ++ +F +P + +PP E
Sbjct: 5 LPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRD---APPPTRAE 61
Query: 94 TPAERRARVHKLRLEKGAAKAAEELEKYDPHNDPNISGDPYKTLFVARLSYETTESRIKR 153
T ER R + ++E+ + EL+ +DPHNDPN GD +KTLFVAR++Y+TTES+++R
Sbjct: 62 TREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRR 121
Query: 154 EFESYGAIKRVRLVTDAESNKPRGYAFIEYLHTRDMKAAYKQADGRKIEGRRVLVDVERG 213
EFE YG IKR+ +V S KPRGYAFIEY H RDM +AYK ADG+KI+GRRVLVDVERG
Sbjct: 122 EFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERG 181
Query: 214 RTVPNWRPRRLGGGLGTTRVGGDEVNQRHSGRE-----QQQSGPSRSEEPRVREERHADR 268
RTV WRPRRLGGGLG TR GG +VN RHSGR+ ++ GPS P +R DR
Sbjct: 182 RTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPS----PLPHRDRDRDR 237
Query: 269 DREKSRERGKDRDRERERSRERSSD-KARDRDRDHREDRHHRDRDRNRDRDRGKERDRER 327
+RE+ RER ++RD+ERER R RS D + R R RD E R R+R +++DRDR + R R
Sbjct: 238 ERER-RERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSR 296
Query: 328 DRG-RDRERGRD-----------------------------------RDRGRERDRDRER 351
+R R+RER + ++GR+RDR+R R
Sbjct: 297 ERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRR 356
Query: 352 DH----ERDVEHDRYREKDKDYEVGE--TDRGRSHDRG 383
H ER + DR R++D++++ GE ++RGR RG
Sbjct: 357 SHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARG 394
Score = 34.7 bits (78), Expect = 0.59
Identities = 49/219 (22%), Positives = 80/219 (36%), Gaps = 55/219 (25%)
Query: 329 RGRDRERGRDRDRGRERDRDRERDHERDVEHDRYREKDKDYEVGETDRGRSHDRGADYDH 388
R RE +R R R++ R E + E + + G+ + R +YD
Sbjct: 59 RAETREERMERKR---REKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVAR-VNYDT 114
Query: 389 VESK--HEKEPHGEIERDYEPDDHHGRYKEPGHGHRHADPEHDPDHYNHYEHQRG----- 441
ESK E E +G I+R + + + G+ + EH+ D ++ Y+H G
Sbjct: 115 TESKLRREFEVYGPIKRIHMV---YSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDG 171
Query: 442 --------RGQYDEG---------------------------DDRGDYNQYPD-----HA 461
RG+ +G DD Y++ P H
Sbjct: 172 RRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHR 231
Query: 462 KMEDDHHTERA-KSKSRDRDRNRDKDHDYHRSERSHSRE 499
+ D ER +S+ RD++R R + R RS SR+
Sbjct: 232 DRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRD 270
>RU17_DROME (P17133) U1 small nuclear ribonucleoprotein 70 kDa (U1
snRNP 70 kDa) (snRNP70)
Length = 448
Score = 283 bits (725), Expect = 6e-76
Identities = 171/434 (39%), Positives = 240/434 (54%), Gaps = 47/434 (10%)
Query: 39 LTANLLKLFEPRPPLEYKPP----PEKRKCPPLTGMAQFVSKFAEPGEPEYSPPVPVVET 94
L NLL LF R P+ + PP P ++K G+A+F++ F +P + +P VET
Sbjct: 5 LPPNLLALFAAREPIPFMPPVDKLPHEKKSRGYLGVAKFMADFEDPKD---TPLPKTVET 61
Query: 95 PAERRARVHKLRLEKGAAKAAEELEKYDPHNDPNISGDPYKTLFVARLSYETTESRIKRE 154
ER R + + E+ A K E+ +DP N + DP++TLF+AR++Y+T+ES+++RE
Sbjct: 62 RQERLERRRREKAEQVAYKLEREIALWDPTEIKNATEDPFRTLFIARINYDTSESKLRRE 121
Query: 155 FESYGAIKRVRLVTDAESNKPRGYAFIEYLHTRDMKAAYKQADGRKIEGRRVLVDVERGR 214
FE YG IK++ L+ D ES KP+GYAFIEY H RDM AAYK ADG+KI+ +RVLVDVER R
Sbjct: 122 FEFYGPIKKIVLIHDQESGKPKGYAFIEYEHERDMHAAYKHADGKKIDSKRVLVDVERAR 181
Query: 215 TVPNWRPRRLGGGLGTTRVGGDEVNQRHSGREQQQSGPSRSEEPRVREERH--------- 265
TV W PRRLGGGLG TR GG++VN +HSGRE + R R RE+R
Sbjct: 182 TVKGWLPRRLGGGLGGTRRGGNDVNIKHSGREDNERERERYRLEREREDREGPGRGGGSN 241
Query: 266 -----------ADRDREKSRERGKDRDRE------------RERSRERSSDKARDRDR-D 301
A+R R +SRER +DR+R+ R RSRER +A R+R D
Sbjct: 242 GLDARPGRGFGAERRRSRSRER-RDRERDRGRGAVASNGRSRSRSRERRKRRAGSRERYD 300
Query: 302 HREDRHHRDRDRNRDRDRGKERDRERDRGRDRERGRDRDRGRERDRDRERDHERDVEHDR 361
+ R RDR+R RDRDR +E+ ++R + R+RE R+R + RDRER +
Sbjct: 301 EFDRRDRRDRERERDRDREREKKKKRSKSRERESSRERRERKRERRDRERGTGSGGDVKE 360
Query: 362 YREKDKDYEVGETDRGRSHDRGADYDHVESKHEKEPHGEIERDYEPDD-HHGRYKEP--- 417
+ +D +V + D +D+ + ++E E E Y P HH + P
Sbjct: 361 RKPDFRDMDVIKIKEEPVDDGYPTFDYQNATIKREIDDEDEEKYRPPPAHHNMFSVPPPP 420
Query: 418 --GHGHRHADPEHD 429
G G+ +P D
Sbjct: 421 ILGRGNASTNPNPD 434
Score = 34.7 bits (78), Expect = 0.59
Identities = 47/204 (23%), Positives = 69/204 (33%), Gaps = 23/204 (11%)
Query: 304 EDRHHRDRDRNRDRDRGKERDRER-----DRGRDRERGRDRDRGRERDRDRERDHERDVE 358
E H RD GK+ D +R +R R + R G R ++ +++
Sbjct: 149 EYEHERDMHAAYKHADGKKIDSKRVLVDVERARTVKGWLPRRLGGGLGGTRRGGNDVNIK 208
Query: 359 HDRYREKDKDYEVGETDRGRSHDRGADYDHVESKHEKEPHGEIERDYEPDDHHGRYKEPG 418
H + +++ E +R R G G D P G +
Sbjct: 209 HSGREDNERERERYRLEREREDREGPG----------RGGGSNGLDARPGRGFGAERRRS 258
Query: 419 HGHRHADPEHDPDHYNHYEHQRGRGQYDEGDDR--GDYNQYPDHAKMEDDHHTERAKSKS 476
D E D + R R + E R G +Y E D R + +
Sbjct: 259 RSRERRDRERDRGRGAVASNGRSRSRSRERRKRRAGSRERYD-----EFDRRDRRDRERE 313
Query: 477 RDRDRNRDKDHDYHRS-ERSHSRE 499
RDRDR R+K +S ER SRE
Sbjct: 314 RDRDREREKKKKRSKSRERESSRE 337
>RU17_MOUSE (Q62376) U1 small nuclear ribonucleoprotein 70 kDa (U1
SNRNP 70 kDa) (snRNP70) (Fragment)
Length = 378
Score = 278 bits (711), Expect = 2e-74
Identities = 156/337 (46%), Positives = 205/337 (60%), Gaps = 65/337 (19%)
Query: 106 RLEKGAAKAAEELEKYDPHNDPNISGDPYKTLFVARLSYETTESRIKREFESYGAIKRVR 165
++E+ + EL+ +DPHNDPN GD +KTLFVAR++Y+TTES+++REFE YG IKR+
Sbjct: 4 KIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIH 63
Query: 166 LVTDAESNKPRGYAFIEYLHTRDMKAAYKQADGRKIEGRRVLVDVERGRTVPNWRPRRLG 225
+V S KPRGYAFIEY H RDM +AYK ADG+KI+GRRVLVDVERGRTV WRPRRLG
Sbjct: 64 MVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLG 123
Query: 226 GGLGTTRVGGDEVNQRHSGRE-----QQQSGPSRSEEPRVREERHADRDREKSRERGKDR 280
GGLG TR GG +VN RHSGR+ ++ GPS P +R DR+RE+ RER ++R
Sbjct: 124 GGLGGTRRGGADVNIRHSGRDDTSRYDERPGPS----PLPHRDRDRDRERER-RERSRER 178
Query: 281 DRERERSRERSSD---KARDRDRDHREDRHHRDRDRNRDRDRGKERDRERDRGRDRERGR 337
D+ERER R RS D ++R RD+D R R +D++RDR R R RER R R+RER
Sbjct: 179 DKERERRRSRSRDRQRRSRSRDKDERRRSRERTKDKDRDRKRRSSRSRERAR-RERERKE 237
Query: 338 D-----------------------------------------------RDRGRERDRDRE 350
+ ++GR+RDR+R
Sbjct: 238 ELRGGGGGGGGGSGGGGGGDMAEPSEAGDGAPDDGPPGELGPEGPDGPEEKGRDRDRERR 297
Query: 351 RDH--ERDVEHDRYREKDKDYEVGE--TDRGRSHDRG 383
R H ER+ DR R++D++++ GE ++RGR RG
Sbjct: 298 RSHRSERERRRDRDRDRDREHKRGERGSERGRDEARG 334
Score = 56.2 bits (134), Expect = 2e-07
Identities = 47/146 (32%), Positives = 59/146 (40%), Gaps = 21/146 (14%)
Query: 225 GGGLGTTRVGGDEVNQRHSGREQQQSGPSRSEEPRVREERHADRDREKSRERGKDRDRER 284
GGG GGD +G GP P + E+G+DRDRER
Sbjct: 246 GGGGSGGGGGGDMAEPSEAGDGAPDDGPPGELGPE---------GPDGPEEKGRDRDRER 296
Query: 285 ERSRERSSDKARDRDRDHREDRHHRDRDRNRDRDRGKERDRERDRGRDRERGRDRDRGRE 344
RS ++ RDRDRD RDR+ R +RG ER R+ RG G +D G E
Sbjct: 297 RRSHRSERERRRDRDRD-------RDREHKRG-ERGSERGRDEARGGG---GSGQDNGLE 345
Query: 345 RDRDRERDHERDVE-HDRYREKDKDY 369
RD + E D Y + Y
Sbjct: 346 GLGSDGRDMYMEAEGGDGYMAPENGY 371
Score = 36.6 bits (83), Expect = 0.16
Identities = 38/171 (22%), Positives = 56/171 (32%), Gaps = 35/171 (20%)
Query: 350 ERDHERDVEHDRYREKDK----------DYEVGETDRGRSHDR-----------GADYDH 388
E +HERD+ H Y+ D D E G T +G R GAD +
Sbjct: 80 EYEHERDM-HSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNI 138
Query: 389 VESKHEKEPHGEIERDYEPDDHHGRYKEPGHGHRHADPEHDPDHYNHYEHQRGRGQYDEG 448
S + + P H R ++ R E D + R R +
Sbjct: 139 RHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRQRRSRS 198
Query: 449 DDRGDYNQYPDHAKMEDDHHTERAKSKSRDRDRNRDKDHDYHRSERSHSRE 499
D+ D+ R ++K +DRDR R R+ R R+
Sbjct: 199 RDK-------------DERRRSRERTKDKDRDRKRRSSRSRERARRERERK 236
Score = 35.4 bits (80), Expect = 0.35
Identities = 18/61 (29%), Positives = 27/61 (43%)
Query: 441 GRGQYDEGDDRGDYNQYPDHAKMEDDHHTERAKSKSRDRDRNRDKDHDYHRSERSHSREY 500
GR D+R + P + D R +S+ RD++R R + R RS SR+
Sbjct: 142 GRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRQRRSRSRDK 201
Query: 501 D 501
D
Sbjct: 202 D 202
>SFRC_HUMAN (Q8WXA9) Splicing factor, arginine/serine-rich 12
(Serine-arginine-rich splicing regulatory protein 86)
(SRrp86) (Splicing regulatory protein 508) (SRrp508)
Length = 508
Score = 125 bits (315), Expect = 2e-28
Identities = 101/422 (23%), Positives = 189/422 (43%), Gaps = 56/422 (13%)
Query: 126 DPNISGDPYKTLFVARLSYETTES-RIKREFESYGAIKRVRLVTDAESNKPRGYAFIEYL 184
DP+ + +T++V L+ +TT + ++ F+ G +K VR+ D +P +AF+E+
Sbjct: 57 DPSKIDEIRRTVYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGD--ETQPTRFAFVEFA 114
Query: 185 HTRDMKAAYK----------------------------QADGRKIEG--RRV-------- 206
+ A QA +++E +RV
Sbjct: 115 DQNSVPRALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFIS 174
Query: 207 -LVDVERGRTVPNWRPRRLGGGLGTTRVGGDEVNQRHSGREQQQSGPSRSEEPRVREERH 265
++ E G++ R+ G TR ++ HS R++ QS RS R
Sbjct: 175 AAIEPESGKS----NERKGGRSRSHTRSKSRSSSKSHSRRKRSQS-KHRSRSHNRSRSRQ 229
Query: 266 ADRDREKS--RERGKDRDRERERSRERSSDKARDRDRDHREDRHHRDRDRNRDRDRGKER 323
DR R KS ++R K R+R + RSR S DK +D +E +++DR ++R+R KER
Sbjct: 230 KDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKER 289
Query: 324 DRERDRGRDRERGRDRDRGRERDRDRERDHERDVEHDRYREKDKDYEVGETDRGRSHDRG 383
++E++RG++++R ++R++ RE+D++++R+ ER+ EH++ R+K+K+ E + ++ R DR
Sbjct: 290 EKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKE-QDKEKEREKDRS 348
Query: 384 ADYDHVESKHEKEPHGEIERDYEPDDHHGRYKEPGHGHRHADPEHDPDHYNHYEHQRGRG 443
+ D K +K R Y R P + + R
Sbjct: 349 KEIDEKRKKDKKS--RTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 406
Query: 444 QYDEGDDRGDYNQYPDHAKMEDDHHTERAKS---KSRDRD-RNRDKDHDYHRSERSHSRE 499
++ D + + + + ER+ S S DRD + + + + E+ H++E
Sbjct: 407 PSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKE 466
Query: 500 YD 501
D
Sbjct: 467 PD 468
Score = 95.9 bits (237), Expect = 2e-19
Identities = 62/228 (27%), Positives = 110/228 (48%), Gaps = 58/228 (25%)
Query: 239 NQRHSGREQQQSGPSRSEEPRVRE-----ERHADRDREKSRERGKDRDRERERSRERSSD 293
++ HS +++ + E+ RV+E ER +++REK +ERGK++DR++ER ++R D
Sbjct: 253 SRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKD 312
Query: 294 KARDRDRDHREDRHHRDRDRNRDRDRGKERDRERDRGRDRERGRDRDR------------ 341
K +DR+R+ RE H +DRD+ +++++ KE++RE+DR ++ + R +D+
Sbjct: 313 KEKDRERE-REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNAS 371
Query: 342 ------GRERDRDRERDHERDV--------------------EHDRYREKDKDYEVGETD 375
RER R R R R + D+ REK++D+ +
Sbjct: 372 RRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRE 431
Query: 376 RGRSHD-RGADYDH-------------VESKHEKEPHGEIERDYEPDD 409
R RS R + D E +H KEP + ++ + D
Sbjct: 432 RERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKD 479
Score = 52.8 bits (125), Expect = 2e-06
Identities = 46/188 (24%), Positives = 80/188 (42%), Gaps = 50/188 (26%)
Query: 241 RHSGREQQQSGPSRSEEPRVREERHA-DRDREKSRERGKDRDRERERSRE---------- 289
R RE+ + + R RE+ H DRD+EK +E+ K+++RE++RS+E
Sbjct: 301 RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK 360
Query: 290 --------------RSSDKARDRDRDHREDRHHRD-------------------RDRNRD 316
RSS + R R R R R +D+ R+
Sbjct: 361 SRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKRE 420
Query: 317 RDR---GKERDRERDRGRDRERGRDRDRGRERDRDRERDHERDVEHDRYREKDKDYEVGE 373
++R + R+RER R+ DRD G+E+ ++ ++ EH++ + EV +
Sbjct: 421 KERDHISERRERERSTSM-RKSSNDRD-GKEK-LEKNSTSLKEKEHNKEPDSSVSKEVDD 477
Query: 374 TDRGRSHD 381
D R+ +
Sbjct: 478 KDAPRTEE 485
>SFRC_MOUSE (Q8BZX4) Splicing factor, arginine/serine-rich 12
(Serine-arginine-rich splicing regulatory protein 86)
(SRrp86)
Length = 494
Score = 122 bits (305), Expect = 3e-27
Identities = 102/410 (24%), Positives = 179/410 (42%), Gaps = 50/410 (12%)
Query: 126 DPNISGDPYKTLFVARLSYETTES-RIKREFESYGAIKRVRLVTDAESNKPRGYAFIEYL 184
DP+ + +T++V L+ +TT + ++ F+ G +K VR+ D +P +AF+E+
Sbjct: 60 DPSKIDEIRRTVYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGD--ETQPTRFAFVEFA 117
Query: 185 HTRDMKAAYKQADGRKIEGRRVLVDVERGRTV--PNWRPRRLGGGL-------------- 228
+ A +G R + ++ V P P+ L
Sbjct: 118 DQNSVPRALA-FNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFI 176
Query: 229 -GTTRVGGDEVNQRHSGREQQQS-----GPSRSEEPRVREE-RHADRDREKSRERGKDRD 281
+ N+R GR + + S+S R R + +H R +SR R KDR
Sbjct: 177 SAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRR 236
Query: 282 R------ERERSRERSSDKARDRDRDHREDRHHRDRDRNRDRDRGKERDRERDRGRDRER 335
R +R +SRER ++R R RD R+D + ++R ++++R KER+RE+DR +D+ER
Sbjct: 237 RSKSPHKKRSKSRERRKSRSRSRSRDKRKDTREKVKERVKEKEREKEREREKDREKDKER 296
Query: 336 GRDRDRGRERDRDRERDHERDVEHDRYREKDKDYEVGETDRGRSHDRGADYDHVESKHEK 395
G+++D +DR++E+DHE++ + ++ +E+DKD E R DR + D K +K
Sbjct: 297 GKNKD----KDREKEKDHEKERDKEKEKEQDKDKE-------REKDRSKETDEKRKKEKK 345
Query: 396 EPHGEIERDYEPDDHHGRYKEPGHGHRHADPEHDPDHYNHYEHQRGRGQYDEGDDRGDYN 455
R Y R P + + R G ++ +
Sbjct: 346 S--RTPPRSYNASRRSRSTSRERRRRRSRSSSRSPRTSKTVKRKSSRSPSPRGRNKKEKK 403
Query: 456 QYPDHAKMEDDHHTERA---KSKSRDRD-RNRDKDHDYHRSERSHSREYD 501
+ + + D ER+ K S DRD + + + E+ HS+E D
Sbjct: 404 REKERDHISDRRERERSTSTKKSSGDRDGKEKVEKSTTPVKEKEHSKESD 453
Score = 56.2 bits (134), Expect = 2e-07
Identities = 43/189 (22%), Positives = 79/189 (41%), Gaps = 32/189 (16%)
Query: 236 DEVNQRHSGREQQQSGPSRSEEPRVREERHA-DRDREKSRERGKDRDRERERSRERSSDK 294
++ +R RE+ + ++ R +E+ H +RD+EK +E+ KD++RE++RS+E +
Sbjct: 281 EKEREREKDREKDKERGKNKDKDREKEKDHEKERDKEKEKEQDKDKEREKDRSKETDEKR 340
Query: 295 ARD--------------------RDRDHREDRHHRDRDRNRDRDRGKERDRERDRGRDRE 334
++ R+R R R R + K RGR++
Sbjct: 341 KKEKKSRTPPRSYNASRRSRSTSRERRRRRSRSSSRSPRTSKTVKRKSSRSPSPRGRNK- 399
Query: 335 RGRDRDRGRERDRDRERDHERDVEHDRYREKDKDYEVGETDRGRSHDRGADYDHVESKHE 394
+E+ R++ERDH D +R R G+ D G+ + E +H
Sbjct: 400 --------KEKKREKERDHISD-RRERERSTSTKKSSGDRD-GKEKVEKSTTPVKEKEHS 449
Query: 395 KEPHGEIER 403
KE + +
Sbjct: 450 KESDATVSK 458
>SFRC_RAT (Q9JKL7) Splicing factor, arginine/serine-rich 12
(Serine-arginine-rich splicing regulatory protein 86)
(SRrp86) (SR-related protein of 86 kDa)
Length = 494
Score = 121 bits (303), Expect = 5e-27
Identities = 101/410 (24%), Positives = 180/410 (43%), Gaps = 50/410 (12%)
Query: 126 DPNISGDPYKTLFVARLSYETTES-RIKREFESYGAIKRVRLVTDAESNKPRGYAFIEYL 184
DP+ + +T++V L+ +TT + ++ F+ G +K VR+ D +P +AF+E+
Sbjct: 60 DPSKIDEIRRTVYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGD--ETQPTRFAFVEFA 117
Query: 185 HTRDMKAAYKQADGRKIEGRRVLVDVERGRTV--PNWRPRRLGGGL-------------- 228
+ A +G R + ++ V P P+ L
Sbjct: 118 DQNSVPRALA-FNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFI 176
Query: 229 -GTTRVGGDEVNQRHSGREQQQS-----GPSRSEEPRVREE-RHADRDREKSRERGKDRD 281
+ N+R GR + + S+S R R + +H R +SR R KDR
Sbjct: 177 SAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRA 236
Query: 282 R------ERERSRERSSDKARDRDRDHREDRHHRDRDRNRDRDRGKERDRERDRGRDRER 335
R +R +SRER ++R R RD R+D + ++R ++R+R KE++RE++R +D+ER
Sbjct: 237 RSKSPHKKRSKSRERRKSRSRSRSRDKRKDTREKVKERVKEREREKEKEREKEREKDKER 296
Query: 336 GRDRDRGRERDRDRERDHERDVEHDRYREKDKDYEVGETDRGRSHDRGADYDHVESKHEK 395
G+++D +DR++E+DHE++ + ++ +E+DKD E R DR + D K +K
Sbjct: 297 GKNKD----KDREKEKDHEKERDKEKEKEQDKDKE-------REKDRSKEADEKRKKEKK 345
Query: 396 EPHGEIERDYEPDDHHGRYKEPGHGHRHADPEHDPDHYNHYEHQRGRGQYDEGDDRGDYN 455
R Y R P + + R G ++ +
Sbjct: 346 S--RTPPRSYNSSRRSRSASRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRGRNKKEKK 403
Query: 456 QYPDHAKMEDDHHTERA---KSKSRDRD-RNRDKDHDYHRSERSHSREYD 501
+ + + D ER+ K S DRD + + + + E+ HS+E D
Sbjct: 404 REKERDHISDRRERERSTSTKKSSSDRDGKEKVEKTNTPVKEKEHSKEAD 453
Score = 57.8 bits (138), Expect = 7e-08
Identities = 46/205 (22%), Positives = 83/205 (40%), Gaps = 40/205 (19%)
Query: 236 DEVNQRHSGREQQQSGPSRSEEPRVREERHA-DRDREKSRERGKDRDRERERSRE----- 289
++ +R RE+ + ++ R +E+ H +RD+EK +E+ KD++RE++RS+E
Sbjct: 281 EKEKEREKEREKDKERGKNKDKDREKEKDHEKERDKEKEKEQDKDKEREKDRSKEADEKR 340
Query: 290 RSSDKARDRDRDHREDRHHRDRDRNRDRDRG----------------------------- 320
+ K+R R + R R R R R R
Sbjct: 341 KKEKKSRTPPRSYNSSRRSRSASRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRGRNKK 400
Query: 321 -KERDRERDRGRDRERGRDRDRGRERDRDRERDHERDVEHDRYREKDKDYEVGETDRGRS 379
K+R++ERD DR ++ DR+ + + + +EK+ E T +
Sbjct: 401 EKKREKERDHISDRRERERSTSTKKSSSDRDGKEKVEKTNTPVKEKEHSKEADSTVSTDA 460
Query: 380 HDRGADYDHVESKHEK----EPHGE 400
++ ESK + +PH E
Sbjct: 461 DEKDTARTEEESKAQHNGNCQPHEE 485
>RU17_YEAST (Q00916) U1 small nuclear ribonucleoprotein 70 kDa
homolog
Length = 300
Score = 119 bits (298), Expect = 2e-26
Identities = 69/194 (35%), Positives = 110/194 (56%), Gaps = 12/194 (6%)
Query: 45 KLFEPRPPLEYKPPPE-----KRKCPPLTGMAQFVSKFAEPGEPEYSPPVPVVETPAERR 99
+LF+PRPPL YK P + ++ P +TG+A +S + E+ P
Sbjct: 14 RLFKPRPPLSYKRPTDYPYAKRQTNPNITGVANLLSTSLKHYMEEFPEGSPNNHLQRYED 73
Query: 100 ARVHKLRLEKGAAKAAEELEKYDPHNDPNISG-DPYKTLFVARLSYETTESRIKREFESY 158
++ K+ K A L+ ++P+ DP+I DPY+T+F+ RL Y+ E +++ F +
Sbjct: 74 IKLSKI---KNAQLLDRRLQNWNPNVDPHIKDTDPYRTIFIGRLPYDLDEIELQKYFVKF 130
Query: 159 GAIKRVRLVTDAESNKPRGYAFIEYLHTRDMKAAYKQAD---GRKIEGRRVLVDVERGRT 215
G I+++R+V D + K +GYAFI + K A+K+ G +I+ R +VD+ERGRT
Sbjct: 131 GEIEKIRIVKDKITQKSKGYAFIVFKDPISSKMAFKEIGVHRGIQIKDRICIVDIERGRT 190
Query: 216 VPNWRPRRLGGGLG 229
V ++PRRLGGGLG
Sbjct: 191 VKYFKPRRLGGGLG 204
>CTF8_HUMAN (Q96D72) Protein C20orf158
Length = 478
Score = 105 bits (263), Expect = 2e-22
Identities = 58/156 (37%), Positives = 87/156 (55%), Gaps = 9/156 (5%)
Query: 234 GGDEVNQRHSGREQQQSGPSRSEEPRVREERH--ADRDREKSRERGKDRDRERERSRERS 291
G + NQ GR++++ E+P + A DR + RERG++ RER+ R R
Sbjct: 313 GHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPRE 372
Query: 292 SDKARDRDRDHREDRHHRDRDRNRDRDRGKERDRERDRGRDRERGRDRDRGRERDRDRER 351
D+ RD+D RD DRNR+R ++R+RE DRG++ +R R+R R RER+RDR R
Sbjct: 373 WDRHRDKDSS-------RDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRR 425
Query: 352 DHERDVEHDRYREKDKDYEVGETDRGRSHDRGADYD 387
D +R +R R+K +D E G + RS + + D
Sbjct: 426 DRDRSRSRERDRDKARDRERGRDRKDRSKSKESARD 461
Score = 79.0 bits (193), Expect = 3e-14
Identities = 49/143 (34%), Positives = 71/143 (49%), Gaps = 3/143 (2%)
Query: 277 GKDRDRERERSRERSSDKARDRDRDHREDRHHRDRDRNRDRDRGKERDRERDRGRDRERG 336
G+ R+R +E+ ++ + R + R R+R RN R+R +R RE DR RD++
Sbjct: 323 GRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSS 382
Query: 337 RDRDRGRER--DRDRERDHERDVEHDRYREKDKDYEVGETDRGRSHDRGADYDHVESKHE 394
RD DR RER +RDRER+ +R E DR RE+ ++ E E DR R DR + K
Sbjct: 383 RDWDRNRERSANRDREREADRGKEWDRSRERSRNRE-RERDRRRDRDRSRSRERDRDKAR 441
Query: 395 KEPHGEIERDYEPDDHHGRYKEP 417
G +D R +P
Sbjct: 442 DRERGRDRKDRSKSKESARDPKP 464
Score = 52.8 bits (125), Expect = 2e-06
Identities = 53/203 (26%), Positives = 79/203 (38%), Gaps = 56/203 (27%)
Query: 301 DHREDRHHRDRDRN---RDRDRGKERDRERDRGRDRERGR-DRDRGRERDRDRERDHERD 356
D RE + H R++ R R+R +E+ +GR DR RER+R R ERD
Sbjct: 307 DFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERD 366
Query: 357 VEHDRYREKDKDYEVGETDRGRSHDRGADYDHVESKHEKEPHGEIERDYEPDDHHGRYKE 416
+ R E DR R D D+D E+ + + ER+ + R +E
Sbjct: 367 WDRPR-----------EWDRHRDKDSSRDWDR---NRERSANRDREREADRGKEWDRSRE 412
Query: 417 PGHGHRHADPEHDPDHYNHYEHQRGRGQYDEGDDRGDYNQYPDHAKMEDDHHTERAKSKS 476
R R + E D R D +R++S+
Sbjct: 413 -----------------------RSRNRERERDRRRD---------------RDRSRSRE 434
Query: 477 RDRDRNRDKDHDYHRSERSHSRE 499
RDRD+ RD++ R +RS S+E
Sbjct: 435 RDRDKARDRERGRDRKDRSKSKE 457
>SFR4_HUMAN (Q08170) Splicing factor, arginine/serine-rich 4
(Pre-mRNA splicing factor SRP75) (SRP001LB)
Length = 494
Score = 99.8 bits (247), Expect = 1e-20
Identities = 98/405 (24%), Positives = 173/405 (42%), Gaps = 45/405 (11%)
Query: 131 GDPYKTLFVARLSYETTESRIK-REFESYGAIKRVRLVTDAESNKPR-GYAFIEYLHTRD 188
G P +T + RL E SR ++ + Y +++ VT A+++K R IE++ D
Sbjct: 97 GPPTRTEY--RLIVENLSSRCSWQDLKDY--MRQAGEVTYADAHKGRKNEGVIEFVSYSD 152
Query: 189 MKAAYKQADGRKIEGRRVLV-----------DVERGRTVPNWRPRRLGGGLGTTRVGGDE 237
MK A ++ DG ++ GR++ + R R+ R R +R G +
Sbjct: 153 MKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSK 212
Query: 238 VNQRHSGREQQQSGPSRSEEPRVREERHADRDREKSRERGKDRDRERERSRERSSDKARD 297
+ S R + +SG + R R + + +EKSR K++ R R S +S K++D
Sbjct: 213 SSHSKS-RSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKD 271
Query: 298 RDRDHREDRHHRDRDRNRDRDRGKERDRERDRGRDR----------ERGRDRDRGRERDR 347
+ + ++ + + ++R R K + + R R ++R RGR +++ + R
Sbjct: 272 QAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSR 331
Query: 348 DRERDHERDVEHDRYREKDKDYEVGETDRGRSHDRGADYDHVESKHEKEPHGEIERDYEP 407
R R R R K KD G R RS + SK E+ +RD +
Sbjct: 332 SRSRSKGGSRSRSRSRSKSKDKRKG---RKRSREESRSRSRSRSKSERSRKRGSKRDSKA 388
Query: 408 DDHHGRYKEPGHGHRHADPEH----DPDHYNHYEHQR-GRGQYDE-GDDRGDYNQYPDHA 461
+ KE + P + +H QR GRG+ + G ++ ++ ++
Sbjct: 389 GSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNS 448
Query: 462 KMEDDHHTE---RAKSKSRDRDRNRDKDHDYHRS-----ERSHSR 498
K + + +E R+KS S+ R R++ + RS RSHSR
Sbjct: 449 KSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
Score = 92.0 bits (227), Expect = 3e-18
Identities = 98/398 (24%), Positives = 147/398 (36%), Gaps = 74/398 (18%)
Query: 137 LFVARLSYETTESRIKREFESYGAIKRVRLVTDAESNKPRGYAFIEYLHTRDMKAAYKQA 196
+++ RLSY+ E ++R F+ YG I V L GY F+E+ RD A +
Sbjct: 4 VYIGRLSYQARERDVERFFKGYGKILEVDL--------KNGYGFVEFDDLRDADDAVYEL 55
Query: 197 DGRKIEGRRVLVDVERGRTVPNWRPRRLGGGLGTTRVGGDEVNQRHSGREQQQSGPSRSE 256
+G+ + G RV+V+ RG PRR G G+ R G R SGR++ GP
Sbjct: 56 NGKDLCGERVIVEHARG-------PRR-DGSYGSGRSG---YGYRRSGRDKY--GPPTRT 102
Query: 257 EPRVREERHADRD-----REKSRERGKDRDRERERSRERS--------SDKAR------- 296
E R+ E + R ++ R+ G+ + + R+ SD R
Sbjct: 103 EYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDG 162
Query: 297 ------------DRDRDHREDRHHRDRDRNRDRDRGKERDRERDRGRDRERGRDRDRGRE 344
D+ R + R R +R R R + + R R + + R R
Sbjct: 163 TEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRS 222
Query: 345 RDRDRERDHERDVEHDRYREKDKDYEVGETDRGRSHDRGADYDHVESKHEKEPHGEIERD 404
R R R R R R K E R S ++ H K + + E
Sbjct: 223 RSGSRSRSKSRSRSQSRSRSKK------EKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEK 276
Query: 405 YEPDDHHGRYKEPGHGHRHADPEHDPDHYNHYEHQRGRGQYD--EGDDRGDYNQYPDHAK 462
+ +D+ G+ K P + R R Q E + RG ++ K
Sbjct: 277 IQNNDNVGKPK-----------SRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEK 325
Query: 463 -MEDDHHTERAKSKSRDRDRNRDKDHDYHRSERSHSRE 499
+ R+K SR R R+R K D R R SRE
Sbjct: 326 SLRQSRSRSRSKGGSRSRSRSRSKSKD-KRKGRKRSRE 362
Score = 32.0 bits (71), Expect = 3.8
Identities = 23/68 (33%), Positives = 28/68 (40%), Gaps = 3/68 (4%)
Query: 227 GLGTTRVGGDEVNQRHSGREQQQSGPSRSEEPRVREERHAD-RDREKSRERGKDRD--RE 283
G G + G R R +S P+ E R R + + R R KSR R R R
Sbjct: 427 GRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRS 486
Query: 284 RERSRERS 291
R RS RS
Sbjct: 487 RSRSHSRS 494
>T2_MOUSE (Q06666) Octapeptide-repeat protein T2
Length = 185
Score = 97.8 bits (242), Expect = 6e-20
Identities = 58/160 (36%), Positives = 83/160 (51%), Gaps = 14/160 (8%)
Query: 240 QRHSGREQQQSGPSRSEEPRVRE---ERHADRDREKSRERGKDRDRERERSRERS----- 291
QR RE + SE R RE +R R RE R+RG++R RE ER ER
Sbjct: 2 QRGREREAESQRVRESERQRGREAERQRERQRGREAERQRGRERGREAEREAERQRGRER 61
Query: 292 ------SDKARDRDRDHREDRHHRDRDRNRDRDRGKERDRERDRGRDRERGRDRDRGRER 345
+++ R R+R +RH R R+ R R R +E +R+R R +RE R R+R RER
Sbjct: 62 QRGRGEAERQRGRERGREVERHRRGREAERQRGREREAERQRGREAEREAERQRERQRER 121
Query: 346 DRDRERDHERDVEHDRYREKDKDYEVGETDRGRSHDRGAD 385
R RE + +R E +R R ++ + + GE RGR + A+
Sbjct: 122 QRGREAERQRGREAERQRGREAEKQRGERQRGREVEAEAE 161
Score = 85.5 bits (210), Expect = 3e-16
Identities = 53/157 (33%), Positives = 85/157 (53%), Gaps = 11/157 (7%)
Query: 239 NQRHSGRE---QQQSGPSRSEEPRVREERHADRDREKSRERGKDRDR---ERERSRERSS 292
++R GRE Q++ R E + ER + +RE R+RG++R R E ER R R
Sbjct: 17 SERQRGREAERQRERQRGREAERQRGRERGREAEREAERQRGRERQRGRGEAERQRGRER 76
Query: 293 DKARDRDRDHREDRHHRDRDRNRDRDRGKERDRE----RDRGRDRERGRDRDRGRERDRD 348
+ +R R RE R R+R +R RG+E +RE R+R R+R+RGR+ +R R R+ +
Sbjct: 77 GREVERHRRGREAERQRGREREAERQRGREAEREAERQRERQRERQRGREAERQRGREAE 136
Query: 349 RERDHERDVEHDRYREKDKDYEVGETDRGRSHDRGAD 385
R+R E + + R++ ++ E RGR + A+
Sbjct: 137 RQRGREAEKQRGE-RQRGREVEAEAEGRGRGMRQEAE 172
Score = 79.3 bits (194), Expect = 2e-14
Identities = 61/193 (31%), Positives = 99/193 (50%), Gaps = 29/193 (15%)
Query: 199 RKIEGRRVLV-DVERGRTVPNWRPRRLGGGLGTTRVGGDEVNQRHSGREQQQSGPSRSEE 257
R+ E +RV + +RGR R R+ G +R GRE+ + +E
Sbjct: 7 REAESQRVRESERQRGREAERQRERQRG-----------REAERQRGRERGREAEREAER 55
Query: 258 PRVREERHA--DRDREKSRERGKD-------RDRERERSRERSSDKARDRDRDHREDRHH 308
R RE + + +R++ RERG++ R+ ER+R RER +++ R R+ + +R
Sbjct: 56 QRGRERQRGRGEAERQRGRERGREVERHRRGREAERQRGREREAERQRGREAEREAERQ- 114
Query: 309 RDRDRNRDRDRGKERDRERDRGR--DRERGRDRDRGR-ERDRDRERDHERDVEHDRYREK 365
R+R R+R RG+E ER RGR +R+RGR+ ++ R ER R RE + E + R++
Sbjct: 115 --RERQRERQRGREA--ERQRGREAERQRGREAEKQRGERQRGREVEAEAEGRGRGMRQE 170
Query: 366 DKDYEVGETDRGR 378
+ E G+ R R
Sbjct: 171 AEATEQGQGQRQR 183
Score = 74.7 bits (182), Expect = 5e-13
Identities = 54/193 (27%), Positives = 84/193 (42%), Gaps = 40/193 (20%)
Query: 311 RDRNRDRDRGKERDRERDRGRDRERGRDRDRGRE--RDRDRERDHERDVEHDRYREKDKD 368
R R R+ + + R+ ER RGR+ ER R+R RGRE R R RER E + E +R R +++
Sbjct: 3 RGREREAESQRVRESERQRGREAERQRERQRGREAERQRGRERGREAEREAERQRGRERQ 62
Query: 369 YEVGETDRGRSHDRGADYDHVESKHEKEPHGEIERDYEPDDHHGRYKEPGHGHRHADPEH 428
GE +R R +RG + + +H + E +R E + R +E A+ E
Sbjct: 63 RGRGEAERQRGRERGREVE----RHRRGREAERQRGREREAERQRGRE-------AEREA 111
Query: 429 DPDHYNHYEHQRGRGQYDEGDDRGDYNQYPDHAKMEDDHHTERAKSKSRDRDRNRDKDHD 488
+ E QRGR E + + R+ +R R ++ +
Sbjct: 112 ERQRERQRERQRGR---------------------------EAERQRGREAERQRGREAE 144
Query: 489 YHRSERSHSREYD 501
R ER RE +
Sbjct: 145 KQRGERQRGREVE 157
Score = 73.6 bits (179), Expect = 1e-12
Identities = 58/179 (32%), Positives = 92/179 (50%), Gaps = 26/179 (14%)
Query: 198 GRKIEGRRVLVDVERGRTVPNWRPRRLGGGLGTTRVGGDEVNQRHSGREQQQSGPSRSEE 257
GR+ E +R + +RGR R R G + +R GRE+Q+ G +E
Sbjct: 22 GREAERQR---ERQRGREAERQRGRERGRE-------AEREAERQRGRERQR-GRGEAER 70
Query: 258 PRVRE-----ERHADRDREKSRERGKDRDRERERSRE--RSSDKARDRDRDHREDRH-HR 309
R RE ERH R RE R+RG++R+ ER+R RE R +++ R+R R+ + R R
Sbjct: 71 QRGRERGREVERHR-RGREAERQRGREREAERQRGREAEREAERQRERQRERQRGREAER 129
Query: 310 DRDRNRDRDRGKERDRERDRGRDRERGRDRD---RGRERDRDRERDHERDVEHDRYREK 365
R R +R RG+E +++R +R+RGR+ + GR R +E + + R R++
Sbjct: 130 QRGREAERQRGREAEKQRG---ERQRGREVEAEAEGRGRGMRQEAEATEQGQGQRQRQR 185
Score = 67.8 bits (164), Expect = 6e-11
Identities = 58/201 (28%), Positives = 88/201 (42%), Gaps = 22/201 (10%)
Query: 152 KREFESYGAIKRVRLVTDAESNKPRGYAFIEYLHTRDMKAAYKQADGRKIEGRRVLVDVE 211
+RE ES +RVR ES + RG R+ + ++ GR+ E +R E
Sbjct: 6 EREAES----QRVR-----ESERQRG---------REAERQRERQRGREAERQR---GRE 44
Query: 212 RGRTVPNWRPRRLGGGLGTTRVGGDEVNQRHSGREQQQSGPSRSEEPRVREERHADRDRE 271
RGR R+ G R + R GRE ++ R E + ER A+R R
Sbjct: 45 RGREAEREAERQRGRERQRGRGEAERQRGRERGREVERHRRGREAERQRGREREAERQRG 104
Query: 272 KSRERGKDRDRERERSRERSSDKARDRDRDHREDRHHRDRDRNRDRDRGKERDRERD-RG 330
+ ER +R RER+R R+R + R R R+ R + +R RG+E + E + RG
Sbjct: 105 REAEREAERQRERQRERQRGREAERQRGREAERQRGREAEKQRGERQRGREVEAEAEGRG 164
Query: 331 RDRERGRDRDRGRERDRDRER 351
R + + + R R+R
Sbjct: 165 RGMRQEAEATEQGQGQRQRQR 185
>NLFE_MOUSE (P19426) Negative elongation factor E (NELF-E) (RD
protein)
Length = 375
Score = 97.1 bits (240), Expect = 1e-19
Identities = 71/176 (40%), Positives = 92/176 (51%), Gaps = 32/176 (18%)
Query: 199 RKIEGRRVLVDVERGRTVPNWRPRRLGGGLGTTRVGGDEVNQRHSGREQQQSGPSR--SE 256
R +EG+ L D E+G VP ++P + + DE Q S R Q++S S
Sbjct: 90 RTLEGK--LKDPEKG-PVPTFQPFQRS-------MSADEDLQEPSRRPQRKSLYESFVSS 139
Query: 257 EPRVREERHADRDREKS--------------RERGKDRDRE---RERSRERSSDKARDRD 299
R+RE + E E G R R RSR+RS D++RDRD
Sbjct: 140 SDRLRELGQDGEEAEAPGAGDGPPRGFDWSYEEHGSARSSASPPRSRSRDRSHDRSRDRD 199
Query: 300 RDHREDRHHRDRDRNRDRDRGKERDRERDRGRDRERGRDRDRGRERDRDRERDHER 355
RD DR DRDR+RDRDR K++DR+RDR RD+ER RDRDR R+R+RDRE R
Sbjct: 200 RDKERDR---DRDRDRDRDRDKDKDRDRDRDRDKERDRDRDRDRDRERDREGPFRR 252
Score = 43.5 bits (101), Expect = 0.001
Identities = 37/151 (24%), Positives = 58/151 (37%), Gaps = 14/151 (9%)
Query: 349 RERDHERDVEHDRYREKDKD-YEVGETDRGRSHDRGADYDHVESKHEKEPHGEIERDYEP 407
R + D++ R + K YE + R + G D + E+ D P
Sbjct: 112 RSMSADEDLQEPSRRPQRKSLYESFVSSSDRLRELGQDGEEAEAPGAG--------DGPP 163
Query: 408 DDHHGRYKEPGHGHRHADPEHDPDHYNHYEHQRGRGQYDEGDDRGDYNQYPDHAKMED-- 465
Y+E G A P ++ R R + E D D ++ D K +D
Sbjct: 164 RGFDWSYEEHGSARSSASPPRSRSRDRSHDRSRDRDRDKERDRDRDRDRDRDRDKDKDRD 223
Query: 466 ---DHHTERAKSKSRDRDRNRDKDHDYHRSE 493
D ER + + RDRDR RD++ + RS+
Sbjct: 224 RDRDRDKERDRDRDRDRDRERDREGPFRRSD 254
Score = 42.0 bits (97), Expect = 0.004
Identities = 23/75 (30%), Positives = 39/75 (51%), Gaps = 1/75 (1%)
Query: 236 DEVNQRHSGREQQQSGPSRSEEPRVRE-ERHADRDREKSRERGKDRDRERERSRERSSDK 294
D + R R++ + + R R+ ++ DRDR++ R++ +DRDR+R+R RER +
Sbjct: 189 DRSHDRSRDRDRDKERDRDRDRDRDRDRDKDKDRDRDRDRDKERDRDRDRDRDRERDREG 248
Query: 295 ARDRDRDHREDRHHR 309
R E R R
Sbjct: 249 PFRRSDSFPERRAPR 263
Score = 36.2 bits (82), Expect = 0.20
Identities = 18/55 (32%), Positives = 27/55 (48%), Gaps = 1/55 (1%)
Query: 447 EGDDRGDYNQYPDHAKMEDDHHTERAKSKSRDRDRNRDKDHDYHRSERSHSREYD 501
+G RG Y +H R++S+ R DR+RD+D D R +R R+ D
Sbjct: 160 DGPPRGFDWSYEEHGSARSSASPPRSRSRDRSHDRSRDRDRDKER-DRDRDRDRD 213
Score = 35.8 bits (81), Expect = 0.27
Identities = 20/72 (27%), Positives = 31/72 (42%), Gaps = 3/72 (4%)
Query: 433 YNHYEHQRGRGQYDEGDDRGDYNQYPDHAKMEDDHHTERAKSKSRDRDRNRDKDHDYHR- 491
+++ EH R R + + D +R + + RDRDR++DKD D R
Sbjct: 168 WSYEEHGSARSSASPPRSRSRDRSHDRSRDRDRDKERDRDRDRDRDRDRDKDKDRDRDRD 227
Query: 492 --SERSHSREYD 501
ER R+ D
Sbjct: 228 RDKERDRDRDRD 239
>SFR4_MOUSE (Q8VE97) Splicing factor, arginine/serine-rich 4
Length = 489
Score = 93.6 bits (231), Expect = 1e-18
Identities = 98/404 (24%), Positives = 163/404 (40%), Gaps = 48/404 (11%)
Query: 131 GDPYKTLFVARLSYETTESRIK-REFESYGAIKRVRLVTDAESNKPR-GYAFIEYLHTRD 188
G P +T + RL E SR ++ + Y +++ VT A+++K R IE++ D
Sbjct: 97 GPPTRTEY--RLIVENLSSRCSWQDLKDY--MRQAGEVTYADAHKGRKNEGVIEFVSYSD 152
Query: 189 MKAAYKQADGRKIEGRRVLV-----------DVERGRTVPNWRPRRLGGGLGTTRVGGDE 237
MK A ++ DG ++ GR++ + R R+ R R +R G +
Sbjct: 153 MKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSK 212
Query: 238 VNQRHSGREQQQSGPSRSE-----EPRVREERHADRDREK---SRERGKDRDRERERSRE 289
+ S + SRS+ + R R ++ R K SR R + D+ R +S++
Sbjct: 213 SSHSKSRSRSRSGSHSRSKSRSRSQSRSRSKKEKSRSPSKDNKSRSRSRSPDKSRSKSKD 272
Query: 290 RSSDKARDRDRDHREDRHHRDRDRNRDRDRGKERDRERDRGRDRERGRDRDRGRERDRDR 349
+ DK ++ D + H R ++ R R +ER E +R R R R +++ R +++
Sbjct: 273 HAEDKLQNNDSAGKAKSHSPSRHDSKSRSRSQERRAEEERRRSVSRARSQEKSRSQEKSL 332
Query: 350 ERDHERDVEHDRYREKDKDYEVGETDRGRSHDRGADYDHVESKHEKEPHGEIERDYE-PD 408
+ R R R KDK +GR R SK E+ +RD +
Sbjct: 333 LKSRSRSRSRSRSRSKDK-------RKGRKRSRDESRSRSRSKSERSRKHSSKRDSKVSS 385
Query: 409 DHHGRYKEPGHGHRHADPEHDPDHYNHYEHQRG-RGQYDEGDDRGDYNQYP-----DHAK 462
K+ H + H + + G RG EG+ N P +K
Sbjct: 386 SSSSSKKKKDTDHSRSPSRSVSKEREHAKAESGQRGSRAEGESEAP-NPEPRARSRSTSK 444
Query: 463 MEDDHHTE---RAKSKSRDRDRNRDKDHDYHRS-----ERSHSR 498
+ + E R+KS S+ R R++ RS RSHSR
Sbjct: 445 SKPNVPAESRSRSKSASKTRSRSKSPSRSASRSPSRSRSRSHSR 488
Score = 90.5 bits (223), Expect = 9e-18
Identities = 97/401 (24%), Positives = 153/401 (37%), Gaps = 77/401 (19%)
Query: 137 LFVARLSYETTESRIKREFESYGAIKRVRLVTDAESNKPRGYAFIEYLHTRDMKAAYKQA 196
+++ RLSY+ E ++R F+ YG I V L GY F+E+ RD A +
Sbjct: 4 VYIGRLSYQARERDVERFFKGYGKILEVDL--------KNGYGFVEFDDLRDADDAVYEL 55
Query: 197 DGRKIEGRRVLVDVERGRTVPNWRPRRLGGGLGTTRVGGDEVNQRHSGREQQQSGPSRSE 256
+G+ + G RV+V+ RG PRR G G+ R G R SGR++ GP
Sbjct: 56 NGKDLCGERVIVEHARG-------PRR-DGSYGSGRSG---YGYRRSGRDKY--GPPTRT 102
Query: 257 EPRVREERHADRD-----REKSRERGKDRDRERERSRERS--------SDKARDRDR--- 300
E R+ E + R ++ R+ G+ + + R+ SD R ++
Sbjct: 103 EYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDG 162
Query: 301 ------------DHREDRHHRDRDRNRDRDRGKERDRERDRGRDRERGRDRDRGRERDRD 348
D R R R+R R + R R + R R + R R
Sbjct: 163 TEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRS 222
Query: 349 RERDHERDVEHDRYR-----EKDKDYEVGETDRGRSHDRGADYDHVESKHEKEPHGEIER 403
R H R R + +K+K + ++ RS R D +SK E
Sbjct: 223 RSGSHSRSKSRSRSQSRSRSKKEKSRSPSKDNKSRSRSRSPDKSRSKSKDHAED------ 276
Query: 404 DYEPDDHHGRYKEPGHGHRHADPEHDPDHYNHYEHQRGRGQYDEGDDRGDYNQYPDHAKM 463
+ +D G+ K H P ++ R + + E + R ++ K
Sbjct: 277 KLQNNDSAGKAK-----------SHSPSRHDSKSRSRSQERRAEEERRRSVSRARSQEKS 325
Query: 464 EDDHHT---ERAKSKSRDRDRNRDKDHDYHRS---ERSHSR 498
+ R++S+SR R R++DK RS RS SR
Sbjct: 326 RSQEKSLLKSRSRSRSRSRSRSKDKRKGRKRSRDESRSRSR 366
>PPIG_RAT (O55035) Peptidyl-prolyl cis-trans isomerase G (EC
5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G)
(Rotamase G) (Cyclophilin G) (Matrin cyclophilin)
(Matrin-cyp)
Length = 752
Score = 93.6 bits (231), Expect = 1e-18
Identities = 83/357 (23%), Positives = 153/357 (42%), Gaps = 73/357 (20%)
Query: 198 GRKIEGR-----------RVLVDVERGRTVPNWRP-----RRLGGGLGTTRVGGDEVNQR 241
GRKI+GR R R T P+WR +R+ G + GD+ ++
Sbjct: 328 GRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDK-SEL 386
Query: 242 HSGREQQQSGPSRSEEPRVREERHAD--------------------RDREKSRERGKD-- 279
+ +E Q+S P R +E ++ + RH ++R+ R GKD
Sbjct: 387 NEIKENQRS-PVRVKEKKITDHRHMSESPNRGIEKGGKVKDHKLESKERDIRRNSGKDDK 445
Query: 280 ------RDRERERSRERSSDKARDRDRDHREDRHHRDRDRNRDRDRGKERDRERDRGRDR 333
+ R + +SR +S ++++ ++RD + RH R R+R ++R E +E+++ D
Sbjct: 446 YNKNKVKKRGKSKSRSKSKERSKSKERDSKHSRHEDKRVRSRSKERDHETTKEKEKQLD- 504
Query: 334 ERGRDRDRGRERDRDRERDHERDVEHDRYREKDKDYEVGETDRGRSHDRGADYDHVESKH 393
+G+D++R R ++ ++ + + + EHD + K+KD R+ R + D +SKH
Sbjct: 505 SKGKDQERSRSKENSKQVESKSN-EHDHSKSKEKD--------RRAQSRSRERDLTKSKH 555
Query: 394 -------EKEPHGEIERDYEPDDHHGRYKEPGHGHRHADPEHDPDHYNHYEHQRGRGQYD 446
E+ + R H HR+ + E+ +RGR +
Sbjct: 556 SYNSRTRERSRSRDRSRRVRSRSHDRDRSRSKEYHRYREQEY---------RRRGRSRSR 606
Query: 447 EGDDRGDYNQYPDHAKMEDDHHTERAKSKSRDRDRNRDKD-HDYHRSERSHSREYDY 502
+ G + D +ER +S+SR++++ R +D HR E S + Y
Sbjct: 607 DRRTPGRSRSKDRRRRRRDSRSSEREESQSRNKEKYRSQDSKSSHRKENSEGEKRMY 663
Score = 85.1 bits (209), Expect = 4e-16
Identities = 67/279 (24%), Positives = 116/279 (41%), Gaps = 27/279 (9%)
Query: 239 NQRHSGREQQQSGPSRSEEPRVREERHADRDREKSRER-----GKDRDRERERSRERSSD 293
++ S +++ S SR E+ RVR R +RD E ++E+ K +D+ER RS+E S
Sbjct: 463 SKERSKSKERDSKHSRHEDKRVRS-RSKERDHETTKEKEKQLDSKGKDQERSRSKENSKQ 521
Query: 294 ---KARDRDRDHREDRHHRDRDRNRDRDRGKERDRERDRGRDRERGRDRDRGRERDRDRE 350
K+ + D +++ R + R+R+RD K + R R+R R RDR R R R R
Sbjct: 522 VESKSNEHDHSKSKEKDRRAQSRSRERDLTKSKHSYNSRTRERSRSRDRSR---RVRSRS 578
Query: 351 --RDHERDVEHDRYREKD-------KDYEVGETDRGRSHDRGADYDHVESKHEKEPHGEI 401
RD R E+ RYRE++ + + R RS DR S +E
Sbjct: 579 HDRDRSRSKEYHRYREQEYRRRGRSRSRDRRTPGRSRSKDRRRRRRDSRSSEREESQSRN 638
Query: 402 ERDYEPDDHHGRYKEPGHGHRHADPEHDPDHYNHYEHQRGRGQYDEG------DDRGDYN 455
+ Y D +++ DH + ++ + D+ D
Sbjct: 639 KEKYRSQDSKSSHRKENSEGEKRMYSKSRDHSSSNNNREKKADIDQSPVSKTKQSSQDNE 698
Query: 456 QYPDHAKMEDDHHTERAKSKSRDRDRNRDKDHDYHRSER 494
K ++D T K + + ++ DH + ++++
Sbjct: 699 VKSSTLKNQEDEKTRSPVEKENQKSKGQENDHVHDKNKK 737
Score = 79.3 bits (194), Expect = 2e-14
Identities = 68/255 (26%), Positives = 107/255 (41%), Gaps = 34/255 (13%)
Query: 244 GREQQQSGPSRSEEPRVREERHADRDREKSRE---RGKDRDRERERSRERSSDKARDRDR 300
G++Q++S E + E + + D KS+E R + R RER+ ++ + S +R R+R
Sbjct: 507 GKDQERS--RSKENSKQVESKSNEHDHSKSKEKDRRAQSRSRERDLTKSKHSYNSRTRER 564
Query: 301 DHREDRHHRDRDRNRDRDRGKERD-----------RERDRGRD-----RERGRDRDRGRE 344
DR R R R+ DRDR + ++ R R R RD R R +DR R R
Sbjct: 565 SRSRDRSRRVRSRSHDRDRSRSKEYHRYREQEYRRRGRSRSRDRRTPGRSRSKDRRRRRR 624
Query: 345 RDRDRERDHERDVEHDRYREKD-KDYEVGETDRGRSHDRGADYDHVESKHEKEPHGEIER 403
R ER+ + ++YR +D K E G DH S + +E +I++
Sbjct: 625 DSRSSEREESQSRNKEKYRSQDSKSSHRKENSEGEKRMYSKSRDHSSSNNNREKKADIDQ 684
Query: 404 D----YEPDDHHGRYKEPGHGHRHADPEHDPDHYNHYEHQRGRGQYDEGDDRGDYNQYPD 459
+ K ++ + P E+Q+ +GQ E D D N+ D
Sbjct: 685 SPVSKTKQSSQDNEVKSSTLKNQEDEKTRSP---VEKENQKSKGQ--ENDHVHDKNKKCD 739
Query: 460 HAKMEDDHHTERAKS 474
H E T+ KS
Sbjct: 740 H---ESSPGTDEDKS 751
Score = 53.5 bits (127), Expect = 1e-06
Identities = 64/301 (21%), Positives = 107/301 (35%), Gaps = 44/301 (14%)
Query: 236 DEVNQRHSGREQQQSGPSRSEEPRVREERHADRDREKSRERGKDRDRERERSRERSSD-- 293
D + S + S + E+ R R+++H R+ +E+ K + ++ S E +D
Sbjct: 203 DSSSDSQSSSDSSDSETASEEKSRKRKKKHRKNSRKHKKEKKKRKKSKKSPSSESEADNV 262
Query: 294 ----------------------------KARDRDRDHREDRHHRDRDRNRDRDRGKERDR 325
KA D++R +RE R+ + + +R
Sbjct: 263 DAQPQSTVRPEEIPPIPENRFLMRKSPPKADDKERKNRERERERECNPPNSQPASYQRRF 322
Query: 326 ERDRGRDRERGRDRDRGRERDRDRERDHERDVEHDRYREKDKDYEVGETDRGRSHDRGAD 385
R + +GR R R R R RD R E + ++ + + R S +R
Sbjct: 323 LVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWR--QEMQRAQRMRVSSGERWIK 380
Query: 386 YDHVESKHEKEPHGEIERDYEP--DDHHGRYKEPGHGHRHADPEHDPDHYNHYEHQRGRG 443
D E KE R E DH + P G D H+
Sbjct: 381 GDKSELNEIKENQRSPVRVKEKKITDHRHMSESPNRGIEKGGKVKD--------HKLESK 432
Query: 444 QYDEGDDRGDYNQYPDHAKMEDDHHTERAKSKSRDRDRNRDKDHDYHRSE--RSHSREYD 501
+ D + G ++Y + + R+KSK R + + RD H H + RS S+E D
Sbjct: 433 ERDIRRNSGKDDKYNKNKVKKRGKSKSRSKSKERSKSKERDSKHSRHEDKRVRSRSKERD 492
Query: 502 Y 502
+
Sbjct: 493 H 493
>NLFE_HUMAN (P18615) Negative elongation factor E (NELF-E) (RD
protein)
Length = 380
Score = 92.8 bits (229), Expect = 2e-18
Identities = 74/223 (33%), Positives = 105/223 (46%), Gaps = 24/223 (10%)
Query: 143 SYETTESRIKREFESYGAIKRVRLVTDAESNKPRGYAFIEYLHTRDMKAAYKQADGRKIE 202
S T++ +KR + A+ G I + + +K++ R +E
Sbjct: 38 SSTTSQGGVKRSLSEQPVMDTATATEQAKQLVKSGA--ISAIKAETKNSGFKRS--RTLE 93
Query: 203 GRRVLVDVERGRTVPNWRPRRLGGGLGTTRVGGDEVNQRHSGREQQQSGPSR--SEEPRV 260
G+ L D E+G VP ++P + + D+ Q S R Q++S S R+
Sbjct: 94 GK--LKDPEKG-PVPTFQPFQRS-------ISADDDLQESSRRPQRKSLYESFVSSSDRL 143
Query: 261 REERHADRDRE-----KSRERGKDRDRERERSRERSSDKARDRDRDHREDRHHRDRDRNR 315
RE + E R D E S+ R R RD H R+RDR+R
Sbjct: 144 RELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRS---HERNRDRDR 200
Query: 316 DRDRGKERDRERDRGRDRERGRDRDRGRERDRDRERDHERDVE 358
DR+R ++RDR+RDR RDR+R RDRDR RERDRDRERD +RD E
Sbjct: 201 DRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243
Score = 91.3 bits (225), Expect = 5e-18
Identities = 51/109 (46%), Positives = 64/109 (57%), Gaps = 11/109 (10%)
Query: 247 QQQSGPSRSEEPRVREERHADRDREKSRERGKDRDRERERSRERSSDKARDRDRDHREDR 306
++ GP + P R D E+ R RSR+RS ++ RDRDRD
Sbjct: 151 EEAEGPGAGDGP----PRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRD----- 201
Query: 307 HHRDRDRNRDRDRGKERDRERDRGRDRERGRDRDRGRERDRDRERDHER 355
R+RDR+RDRDR +ERDR+RDR RDR+R RDRDR R+RDRDRE R
Sbjct: 202 --RERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGPFRR 248
Score = 57.4 bits (137), Expect = 9e-08
Identities = 35/99 (35%), Positives = 51/99 (51%), Gaps = 6/99 (6%)
Query: 225 GGGLGTTRV---GGDEVNQRHSGREQQQSGPSRSEEPRVRE---ERHADRDREKSRERGK 278
G G G R G +E + HS +S R R+ +R DRDR++ R+R +
Sbjct: 157 GAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRER 216
Query: 279 DRDRERERSRERSSDKARDRDRDHREDRHHRDRDRNRDR 317
DRDR+R+R R+R D+ R+RDRD + R D +R
Sbjct: 217 DRDRDRDRDRDRERDRDRERDRDRDREGPFRRSDSFPER 255
Score = 43.1 bits (100), Expect = 0.002
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 3/74 (4%)
Query: 236 DEVNQRHSGREQQQSGPSRSEEPRVREERHADRDREKSRERGKDRDRERERSRERSSDKA 295
D ++R+ R++ + + R RE DRDR++ R+R ++RDR+RER R+R +
Sbjct: 189 DRSHERNRDRDRDRERDRDRDRDRDRER---DRDRDRDRDRDRERDRDRERDRDRDREGP 245
Query: 296 RDRDRDHREDRHHR 309
R E R R
Sbjct: 246 FRRSDSFPERRAPR 259
Score = 42.0 bits (97), Expect = 0.004
Identities = 33/137 (24%), Positives = 54/137 (39%), Gaps = 9/137 (6%)
Query: 358 EHDRYREKDKDYEVGETDRGRSHDRGADYDHVESKHEKEPHGEIERDYEPDDHHGRYKEP 417
E R ++ YE + R + G D + E G D P Y+E
Sbjct: 122 ESSRRPQRKSLYESFVSSSDRLRELGPDGEEAE--------GPGAGDGPPRSFDWGYEER 173
Query: 418 GHGHRHADPEHDPDHYNHYEHQRGRGQYDEGDDRGDYNQYPDHAKMED-DHHTERAKSKS 476
H A P +E R R + E D D ++ + + D D +R + +
Sbjct: 174 SGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRD 233
Query: 477 RDRDRNRDKDHDYHRSE 493
R+RDR+RD++ + RS+
Sbjct: 234 RERDRDRDREGPFRRSD 250
>PPIG_HUMAN (Q13427) Peptidyl-prolyl cis-trans isomerase G (EC
5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G)
(Rotamase G) (Cyclophilin G) (Clk associating
RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SRcyp)
(CASP10)
Length = 754
Score = 89.4 bits (220), Expect = 2e-17
Identities = 84/354 (23%), Positives = 146/354 (40%), Gaps = 67/354 (18%)
Query: 198 GRKIEGR-----------RVLVDVERGRTVPNWRP-----RRLGGGLGTTRVGGDEV--- 238
GRKI+GR R R T P+WR +R+ G + GD+
Sbjct: 330 GRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELN 389
Query: 239 ----NQRHSGREQQQS---------GPSRSEEPRVREERHADRDREKSRERGKDRD---- 281
NQR R +++ P+R E + + H +E+ R ++D
Sbjct: 390 EIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYK 449
Query: 282 ---------RERERSRERSSDKARDRDRDHREDRHHRDRDRNRDRDRGKERDRERD-RGR 331
+ R +S+E+S K RD + E++ R R + RD + KE++++ D +G+
Sbjct: 450 NKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGK 509
Query: 332 DRERGRDRDRGRE-RDRDRERDHERDVEHDRYREKDKDYEVGETDRGRSHDRGADYDHVE 390
D+ER R +++ ++ + E DH + E DR R + + E T S++
Sbjct: 510 DQERSRSKEKSKQLESKSNEHDHSKSKEKDR-RAQSRSRECDITKGKHSYN-----SRTR 563
Query: 391 SKHEKEPHGEIERDYEPDDHHGRYKEPGHGHRHADPEHDPDHYNHYEHQRGRGQYDEGDD 450
+ R D R KE HR+ + E+ +RGR + E
Sbjct: 564 ERSRSRDRSRRVRSRTHDRDRSRSKE---YHRYREQEY---------RRRGRSRSRERRT 611
Query: 451 RGDYNQYPD-HAKMEDDHHTERAKSKSRDRDRNRDKD-HDYHRSERSHSREYDY 502
++ D + D +ER +S+SR++D+ R+++ HR E S S + Y
Sbjct: 612 PPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMY 665
Score = 84.7 bits (208), Expect = 5e-16
Identities = 66/252 (26%), Positives = 111/252 (43%), Gaps = 36/252 (14%)
Query: 239 NQRHSGREQQQSGPSRSEEPRVREERHADRDREKSRER-----GKDRDRERERSRERSSD 293
++ S +++ S +R+EE R+R R RD E +E+ K +D+ER RS+E+S
Sbjct: 464 SKEKSKSKERDSKHNRNEEKRMRS-RSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQ 522
Query: 294 ---KARDRDRDHREDRHHRDRDRNRDRDRGKERDRERDRGRDRERGRDRDRGRERDRDRE 350
K+ + D +++ R + R+R+ D K + R R+R R RDR R R R R +
Sbjct: 523 LESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSR-RVRSRTHD 581
Query: 351 RDHERDVEHDRYREKDKDYEVGETDRGRSHDRGADYDHVESKHEKEPHGEIERDYEPDDH 410
RD R E+ RYRE+ E R RS +R SK D
Sbjct: 582 RDRSRSKEYHRYREQ----EYRRRGRSRSRERRTPPGRSRSK----------------DR 621
Query: 411 HGRYKEPGHGHRHADPEHDPDHYNHYEHQRGRGQYDEGDDRGDYNQYPDHAKMEDDHHTE 470
R ++ R + D Y + E + + + ++ Y++ DH + +
Sbjct: 622 RRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDH------NSSN 675
Query: 471 RAKSKSRDRDRN 482
++ K DRD++
Sbjct: 676 NSREKKADRDQS 687
Score = 64.3 bits (155), Expect = 7e-10
Identities = 44/176 (25%), Positives = 86/176 (48%), Gaps = 22/176 (12%)
Query: 245 REQQQSGPSRSEEPRVREERHA----DRDREKSRERGK-------DRDRERERSRERSSD 293
+E+ + SRS E + + +H+ R+R +SR+R + DRD R RS +
Sbjct: 536 KEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRD------RSRSKE 589
Query: 294 KARDRDRDHREDRHHRDRDRNRDRDRGKERDRERDRGRDRERGRDRDRGRERDRDRERDH 353
R R++++R R R R R R G+ R ++R R R R +R+ + R++D+ R+
Sbjct: 590 YHRYREQEYR--RRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQ 647
Query: 354 ERDVEHDRYREKDKDYEVGETDRGRSHDRGADYDHVESKHEKEPHGEIERDYEPDD 409
E H R+++ + E + R H+ + ++ ++ P +I++ + D+
Sbjct: 648 ESKSSH---RKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDDE 700
Score = 62.0 bits (149), Expect = 3e-09
Identities = 51/210 (24%), Positives = 88/210 (41%), Gaps = 17/210 (8%)
Query: 199 RKIEGRRVLVDVERGRTVPNWRPRRLGGGLGTTRVGGDEVNQR--------HSGREQQ-- 248
R+ + R D+ +G+ N R R +R + R H REQ+
Sbjct: 540 RRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYR 599
Query: 249 QSGPSRSEEPRVREERHADRDREKSRERGKDRDRERERSRERSSDKARDRDRDHREDRHH 308
+ G SRS E R R +DR R R R ERE S+ R+ DK R+++ + H
Sbjct: 600 RRGRSRSRERRTPPGRSRSKDRR--RRRRDSRSSEREESQSRNKDKYRNQE---SKSSHR 654
Query: 309 RDRDRNRDRDRGKERDRERDRGRDRERGRDRDRGRERDRDRERDHERDVEHDRYREKDKD 368
++ + R K RD RE+ DRD+ + ++ + +++ + K+ +
Sbjct: 655 KENSESEKRMYSKSRD-HNSSNNSREKKADRDQS-PFSKIKQSSQDDELKSSMLKNKEDE 712
Query: 369 YEVGETDRGRSHDRGADYDHVESKHEKEPH 398
++ +G + DHV K++K H
Sbjct: 713 KIRSSVEKENQKSKGQENDHVHEKNKKFDH 742
Score = 47.0 bits (110), Expect = 1e-04
Identities = 57/294 (19%), Positives = 110/294 (37%), Gaps = 41/294 (13%)
Query: 236 DEVNQRHSGREQQQSGPSRSEEPRVREERHADRDREKSRERGKDRDRERERSRE------ 289
D + S + S + E+ + R+++H R+ +E+ K + ++ S E
Sbjct: 205 DSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENL 264
Query: 290 ------------------------RSSDKARDRDRDHREDRHHRDRDRNRDRDRGKERDR 325
+S KA +++R +RE R+ + + +R
Sbjct: 265 EAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRL 324
Query: 326 ERDRGRDRERGRDRDRGRERDRDRERDHERDVE-HDRYREKDKDYEVGETDRGRSHDRGA 384
R + +GR R R R R RD R E +R++ + + G +G
Sbjct: 325 LVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGD 384
Query: 385 DYDHVESKHEKEPHGEIERDYEPDDHHGRYKEPGHGHRHADPEHDPDHYNHYEHQRGRGQ 444
+ E K + + ++ + DH + P +R + E + +R +
Sbjct: 385 KSELNEIKENQRSPVRV-KERKITDHRNVSESP---NRKNEKEKKVKDHKSNSKERDIRR 440
Query: 445 YDEGDDRGDYNQYPDHAKMEDDHHTERAKSKSRDRDRNRDKDHDYHRSERSHSR 498
E DD+ N+ AK + R+KSK + + + RD H+ + +R SR
Sbjct: 441 NSEKDDKYK-NKVKKRAKSK-----SRSKSKEKSKSKERDSKHNRNEEKRMRSR 488
>SRCH_RABIT (P16230) Sarcoplasmic reticulum histidine-rich
calcium-binding protein precursor
Length = 852
Score = 89.0 bits (219), Expect = 3e-17
Identities = 65/262 (24%), Positives = 99/262 (36%), Gaps = 11/262 (4%)
Query: 241 RHSGREQQQSGPSRSEEPRVREERHADRDREKSRERGKDRDRERERSRERSSDKARDRDR 300
RH G +++ E +RH RE D D + E S R R
Sbjct: 284 RHRGHREEEDEDDDDEGDSTESDRHQAHRHRGHREEEDDDDDDDEGDSTESDRHQAHRHR 343
Query: 301 DHREDRHHRDRDRNRDRDRGKERDRERDRG-RDRERGRDRDRGRERDRDRERDHERDVEH 359
HRE+ D D D R RG R+ E D D G + DR + H H
Sbjct: 344 GHREEEDEDDDDEG-DSTESDRHQAHRHRGHREEEDEDDDDEGDSTESDRHQAHR----H 398
Query: 360 DRYREKDKDYEVGETDRGRSHDRGADYDHVESKHEKEPHGEIERDYEPDDHHGRYKEPGH 419
+RE++ + + E D S D + H + E++ + E D D H ++ GH
Sbjct: 399 RGHREEEDEDDDDEGDSTES-DHHQAHRHRGHREEEDEEDDDEGDSTESDRHQAHRHRGH 457
Query: 420 GHRHADPEHDPDHYNHYEHQRGRGQYDEGDDRGDYNQYPDHAKMEDDHHTERAKSKSRDR 479
G + + D ++H H+ RG E DD GD + D E+ H R + ++
Sbjct: 458 GEEEDEDDDDEGEHHHVPHRGHRGH--EEDDGGDDDDGDD--STENGHQAHRHQGHGKEE 513
Query: 480 DRNRDKDHDYHRSERSHSREYD 501
+H +H + H D
Sbjct: 514 AEVTSDEHHHHVPDHGHQGHGD 535
Score = 88.2 bits (217), Expect = 5e-17
Identities = 80/307 (26%), Positives = 114/307 (37%), Gaps = 19/307 (6%)
Query: 207 LVDVERGRTVPNWRPRRLGGGL-GTTRVGGDEVNQRHSGREQQQSGPSRSEEPRVREERH 265
++ ER R V PR GG G +EV+ H R + ++ +RH
Sbjct: 163 VISSERPRHVLRRAPRGHGGEEEGEEEEEEEEVSPEHRHRGHGKEDEEDEDDDSTESDRH 222
Query: 266 -ADRDREKSRERGKDRDRERERSRERSSDKARDRDRDHREDRHHRDRDRNRDRDRGKERD 324
A R R E +D D + S E +A R R H E+ D D D
Sbjct: 223 QAHRHRGHREEEDEDDDDDEGDSTESDHHQAH-RHRGHEEEEDEEDDDDEGDSTESDRHQ 281
Query: 325 RERDRG-RDRERGRDRDRGRERDRDRERDHERDVEHDRYREKDKDYEVGETDRGRSHDRG 383
R RG R+ E D D G + DR + H H +RE++ D + + DR
Sbjct: 282 AHRHRGHREEEDEDDDDEGDSTESDRHQAHR----HRGHREEEDDDDDDDEGDSTESDRH 337
Query: 384 ADYDHVESKHEKEPHGEIERDYEPDDHHGRYKEPGHGHRHADPEHDPDHYNHYE---HQ- 439
+ H + E++ + E D D H ++ GHR + E D D + E HQ
Sbjct: 338 QAHRHRGHREEEDEDDDDEGDSTESDRHQAHRH--RGHREEEDEDDDDEGDSTESDRHQA 395
Query: 440 -RGRGQYDE----GDDRGDYNQYPDHAKMEDDHHTERAKSKSRDRDRNRDKDHDYHRSER 494
R RG +E DD GD + H H E + D + + D R
Sbjct: 396 HRHRGHREEEDEDDDDEGDSTESDHHQAHRHRGHREEEDEEDDDEGDSTESDRHQAHRHR 455
Query: 495 SHSREYD 501
H E D
Sbjct: 456 GHGEEED 462
Score = 86.7 bits (213), Expect = 1e-16
Identities = 67/269 (24%), Positives = 101/269 (36%), Gaps = 21/269 (7%)
Query: 241 RHSGREQQQSGPSRSEEPRVREERHADRDREKSRERGKDRDRERERSRERSSDKARDRDR 300
RH G E+++ +E E R + +D D + E S R R
Sbjct: 255 RHRGHEEEEDEEDDDDEGDSTESDRHQAHRHRGHREEEDEDDDDEGDSTESDRHQAHRHR 314
Query: 301 DHREDRHHRDRDRNRDRDRGKERDRERDRG-RDRERGRDRDRGRERDRDRERDHERDVEH 359
HRE+ D D D R RG R+ E D D G + DR + H H
Sbjct: 315 GHREEEDDDDDDDEGDSTESDRHQAHRHRGHREEEDEDDDDEGDSTESDRHQAHR----H 370
Query: 360 DRYREKDKDYEVGETDRGRSHDRGADYDHVESKHEKEPHGEIERDYEPDDHHGRYKEPGH 419
+RE++ + + E D S DR + H + E++ + E D DHH ++
Sbjct: 371 RGHREEEDEDDDDEGDSTES-DRHQAHRHRGHREEEDEDDDDEGDSTESDHHQAHRH--R 427
Query: 420 GHRHADPEHDPD---------HYNHYEHQRGRGQYDEGDDRGDYNQYPDHAKMEDDHHTE 470
GHR + E D D H H G + ++ DD G+++ P H E
Sbjct: 428 GHREEEDEEDDDEGDSTESDRHQAHRHRGHGEEEDEDDDDEGEHHHVPHRGHR---GHEE 484
Query: 471 RAKSKSRDRDRNRDKDHDYHRSERSHSRE 499
D D + + H HR + H +E
Sbjct: 485 DDGGDDDDGDDSTENGHQAHR-HQGHGKE 512
Score = 76.6 bits (187), Expect = 1e-13
Identities = 68/282 (24%), Positives = 101/282 (35%), Gaps = 48/282 (17%)
Query: 241 RHSGREQQQSGPSRSEEPRVREERH-ADRDREKSRERGKDRDRE------------RERS 287
RH G +++ E +RH A R R E +D D E R R
Sbjct: 341 RHRGHREEEDEDDDDEGDSTESDRHQAHRHRGHREEEDEDDDDEGDSTESDRHQAHRHRG 400
Query: 288 RERSSDKARDRDRDHREDRHHRDRDRNRDRDRGKERDRERDRGRDRERGRDRDRGRERDR 347
D+ D + D E HH+ +R R +E D E D D R R
Sbjct: 401 HREEEDEDDDDEGDSTESDHHQ---AHRHRGHREEEDEEDDDEGDSTESDRHQAHRHRGH 457
Query: 348 DRERDHERDVEHDRYREKDKDYEVGETDRGRSHDRGAD-YDHVESKHEKEPHGEIERDYE 406
E D + D E + + + + E D G D G D ++ H + HG+ E +
Sbjct: 458 GEEEDEDDDDEGEHHHVPHRGHRGHEEDDGGDDDDGDDSTENGHQAHRHQGHGKEEAEVT 517
Query: 407 PDDHHGRYKEPGHGHR-HADPEHDPDHYNHYEHQRGRGQYDEGDDRGDYNQYPDHAKMED 465
D+HH + P HGH+ H D E + +EG ++Q P HA
Sbjct: 518 SDEHH--HHVPDHGHQGHGDKEGE----------------EEGVSTDHWHQVPRHA---- 555
Query: 466 DHHTERAKSKSRDRDRNRDKDHDY-------HRSERSHSREY 500
HH + + + + H HRS H+ E+
Sbjct: 556 -HHGPGGEEEGGEEELTVKAGHHVASHPPPGHRSREGHAEEH 596
Score = 64.7 bits (156), Expect = 5e-10
Identities = 59/270 (21%), Positives = 100/270 (36%), Gaps = 17/270 (6%)
Query: 234 GGDEVNQRHSGREQQQSGPSRSEEPRVREERHADRDREKSRERGKDRDRERERSRERSSD 293
G + V++ REQ + P E A+ S G + + E S ER
Sbjct: 115 GDESVSEEGVHREQARQAPGHGGHGEAGAEDLAEHG---SHGHGHEEEDEDVISSERPRH 171
Query: 294 KARDRDRDHREDRHHRDRDRNRDRDRGKERDRERDRGRDRERGRDRDRGRERDRDRERDH 353
R R H + + + + + R R G++ E D D + DR + H
Sbjct: 172 VLRRAPRGHGGEEEGEEEE---EEEEVSPEHRHRGHGKEDEEDEDDD---STESDRHQAH 225
Query: 354 ERDVEHDRYREKDKDYEVGETDRGRSHDRGADYDHVESKHEKEPHGEIERDYEPDDHHGR 413
R H ++D D + G++ H H E + E++ + E D D H
Sbjct: 226 -RHRGHREEEDEDDDDDEGDSTESDHHQAHRHRGHEEEEDEEDD--DDEGDSTESDRHQA 282
Query: 414 YKEPGHGHRH---ADPEHDPDHYNHYEHQRGRGQYDEGDDRGDYNQYPDHAKMEDDHHTE 470
++ GH D E D + ++ R RG +E DD D ++ + D H
Sbjct: 283 HRHRGHREEEDEDDDDEGDSTESDRHQAHRHRGHREEEDDDDDDDE--GDSTESDRHQAH 340
Query: 471 RAKSKSRDRDRNRDKDHDYHRSERSHSREY 500
R + + D + D + D S+R + +
Sbjct: 341 RHRGHREEEDEDDDDEGDSTESDRHQAHRH 370
Score = 56.2 bits (134), Expect = 2e-07
Identities = 62/255 (24%), Positives = 92/255 (35%), Gaps = 41/255 (16%)
Query: 241 RHSGREQQQSGPSRSEEPRVREERHADRDREKSRERGKDRDRERERSRERSSDKARDRDR 300
RH G +++ E + H + R RG R+ E E + DR +
Sbjct: 397 RHRGHREEEDEDDDDEGDSTESDHH-----QAHRHRGH-REEEDEEDDDEGDSTESDRHQ 450
Query: 301 DHREDRHHRDRDRNRDRDRGKE--------RDRERDRGRDRERGRD---------RDRGR 343
HR H + D + D D G+ R E D G D + G D R +G
Sbjct: 451 AHRHRGHGEEEDEDDD-DEGEHHHVPHRGHRGHEEDDGGDDDDGDDSTENGHQAHRHQGH 509
Query: 344 ERDR-----DRERDHERDVEHDRYREKDKDYEVGETDRGRSHDRGADYDHVESKHEKEPH 398
++ D H D H + +K+ + E TD R A + +E
Sbjct: 510 GKEEAEVTSDEHHHHVPDHGHQGHGDKEGEEEGVSTDHWHQVPRHAHH----GPGGEEEG 565
Query: 399 GEIERDYEPDDHHGRYKEPGHGHR--HADPEHDPDHYNHYEHQRGRGQYDEGDDRGDYNQ 456
GE E + H + PGH R HA+ EH + H++H+ G D +RG
Sbjct: 566 GEEELTVKAGHHVASHPPPGHRSREGHAE-EHQTEVPGHHQHR--MGDTDTSAERGHPAS 622
Query: 457 YP---DHAKMEDDHH 468
P H + HH
Sbjct: 623 SPRQQGHPPEDTVHH 637
Score = 43.9 bits (102), Expect = 0.001
Identities = 50/248 (20%), Positives = 79/248 (31%), Gaps = 20/248 (8%)
Query: 211 ERGRTVPNWR--PRRLGGGLGTTRVGGDEVNQRHSGREQQQSGPSRSEEPRVREERHADR 268
E G + +W PR G G GG+E +G P E H
Sbjct: 540 EEGVSTDHWHQVPRHAHHGPGGEEEGGEEELTVKAGHHVASHPPPGHRSREGHAEEHQTE 599
Query: 269 DREKSRERGKDRDRERERSRERSSDKARDRDRDHREDRHHRDRDRNRDRDRGKERDRERD 328
+ R D D ER SS + + + HHR + +D
Sbjct: 600 VPGHHQHRMGDTDTSAERGHPASSPRQQGHPPEDTV-HHHRGSLKEEVGPESPGPAGVKD 658
Query: 329 RGRDRERGRDRDRGR--------ERDRDRERDHERDVEHDRYREKDKDYEVGETDRGRSH 380
R + G + + + E + D E H R + + E+D+ E + H
Sbjct: 659 GSRVKRGGSEEEEEQKGTHHHSLEDEEDEEEGHGRSLSQEDQEEEDRRGESAKVQAPLRH 718
Query: 381 DRGADYDHVESKHEKEPHGEIERDYEPDDHHGRYKEPGHGHRHADPEHDPDHYNHYEHQR 440
R + E + E+E G + P+ GR G + + P+ Y
Sbjct: 719 HR---EEEEEEEEEEEEEGRLPFTIIPNPLSGREAAGGASSEESAEDTGPEDTQEY---- 771
Query: 441 GRGQYDEG 448
G Y +G
Sbjct: 772 --GNYQQG 777
Score = 37.0 bits (84), Expect = 0.12
Identities = 45/278 (16%), Positives = 91/278 (32%), Gaps = 23/278 (8%)
Query: 235 GDEVNQRHSGREQQQSGPSRSEEPRVREERHADRDREKSRERGKDRDRERERSRERSSDK 294
G+E ++ + P R ++ D D + S E G R + +E ++
Sbjct: 458 GEEEDEDDDDEGEHHHVPHRGHRGHEEDDGGDDDDGDDSTENGHQAHRHQGHGKE-EAEV 516
Query: 295 ARDRDRDHREDRHHRDRDRNRDRDRGKERD--RERDRGRDRERGRDRDRGRERDRDRERD 352
D H D H+ + G D + R G + + G E +
Sbjct: 517 TSDEHHHHVPDHGHQGHGDKEGEEEGVSTDHWHQVPRHAHHGPGGEEEGGEEELTVKAGH 576
Query: 353 HERDVEHDRYREKDKDYEVGETDRGRSH-------DRGADYDHVESKHEKEPH------- 398
H +R ++ E +T+ H D A+ H S ++ H
Sbjct: 577 HVASHPPPGHRSREGHAEEHQTEVPGHHQHRMGDTDTSAERGHPASSPRQQGHPPEDTVH 636
Query: 399 ---GEIERDYEPDDHHGRYKEPGHGHRHADPEHDPDHYNHYEHQRGRGQYDEGDDRGDYN 455
G ++ + P+ + G + E + + + H + +E ++ G
Sbjct: 637 HHRGSLKEEVGPESPGPAGVKDGSRVKRGGSEEEEEQKGTHHHSL---EDEEDEEEGHGR 693
Query: 456 QYPDHAKMEDDHHTERAKSKSRDRDRNRDKDHDYHRSE 493
+ E+D E AK ++ R +++ + E
Sbjct: 694 SLSQEDQEEEDRRGESAKVQAPLRHHREEEEEEEEEEE 731
>SFR6_HUMAN (Q13247) Splicing factor, arginine/serine-rich 6
(Pre-mRNA splicing factor SRP55)
Length = 344
Score = 88.2 bits (217), Expect = 5e-17
Identities = 82/288 (28%), Positives = 120/288 (41%), Gaps = 45/288 (15%)
Query: 137 LFVARLSYETTESRIKREFESYGAIKRVRLVTDAESNKPRGYAFIEYLHTRDMKAAYKQA 196
+++ RLSY E I+R F YG + V L GY F+E+ +RD A +
Sbjct: 4 VYIGRLSYNVREKDIQRFFSGYGRLLEVDL--------KNGYGFVEFEDSRDADDAVYEL 55
Query: 197 DGRKIEGRRVLVDVERGRTVPNWRPRRLGGGLGTTRVGGDEVNQRHSGREQQQSGPSRSE 256
+G+++ G RV+V+ RG R R G G+ GG ++R SGR++ GP
Sbjct: 56 NGKELCGERVIVEHARGP-----RRDRDGYSYGSRSGGGGYSSRRTSGRDKY--GPPVRT 108
Query: 257 EPRVREERHADRD-----REKSRERGK--DRDRERERSRE-----RS-SDKARDRDR--- 300
E R+ E + R ++ R+ G+ D +ER+ E RS SD R D+
Sbjct: 109 EYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDG 168
Query: 301 ------------DHREDRHHRDRDRNRDRDRGKERDRERDRGRDRERGRDRDRGRERDRD 348
D H R +R R R + R R R R R R R + R R R
Sbjct: 169 TEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRS 228
Query: 349 RERDHERDVEHDRYREKDKDYEVGETDRG-RSHDRGADYDHVESKHEK 395
R + R R + + K ++DRG SH R D E +
Sbjct: 229 RSKGRSRSRSKGR-KSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSR 275
Score = 63.5 bits (153), Expect = 1e-09
Identities = 57/225 (25%), Positives = 90/225 (39%), Gaps = 27/225 (12%)
Query: 131 GDPYKTLFVARLSYETTESRIKREFESYGAIKRVRLVTDAESNKPR-GYAFIEYLHTRDM 189
G P +T + RL E SR + + +++ VT A+++K R IE+ DM
Sbjct: 103 GPPVRTEY--RLIVENLSSRCSWQ-DLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDM 159
Query: 190 KAAYKQADGRKIEGRRVLVDVERGRTVPNWRPRRLGGGLGTTRVGGDEVNQRHSGREQQQ 249
K A + DG +I GR + + ++ RT + +SG +
Sbjct: 160 KRALDKLDGTEINGRNIRLIEDKPRT---------------------SHRRSYSGSRSRS 198
Query: 250 SGPSRSEEPRVREERHADRDREKSRERGKDRDRERERSRERSSDKARDRDRDHREDRHHR 309
RS R R R KSR R + R + R RSR + + DR
Sbjct: 199 RSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSH 258
Query: 310 DRDRNRDRDRGKERDRERDRGRD-RERGRDRDRGRERDRDRERDH 353
R+R +D E+ R R R R +E G+ + + R R + R +
Sbjct: 259 SHSRSRSKDE-YEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSN 302
>RMX2_MOUSE (Q8R0F5) RNA binding motif protein, X-linked 2
Length = 326
Score = 87.4 bits (215), Expect = 8e-17
Identities = 74/301 (24%), Positives = 125/301 (40%), Gaps = 38/301 (12%)
Query: 137 LFVARLSYETTESRIKREFESYGAIKRVRLVTDAESNKPRGYAFIEYLHTRDMKAAYKQA 196
+FV L YE TE I F YG I + LV D ++ K +G+ F+ Y R A
Sbjct: 38 IFVGGLPYELTEGDIICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTVLAVDNF 97
Query: 197 DGRKIEGRRVLVDVERGRTVPNWR-PRRLGGGLGTTRVGGDEVNQRHSGREQQQSGP--- 252
+G KI+GR + VD V N+R P+ TR E+ ++ G + S P
Sbjct: 98 NGIKIKGRTIRVD-----HVSNYRAPQESEDVDDVTR----ELQEKGCGVKTPPSSPPEV 148
Query: 253 SRSEEPRVREERHADRDREKSRERGKD-----------------RDRERERSRERSSDKA 295
S E+ ++ ++ D+ +K R++ K ++++ ER+ + S K
Sbjct: 149 SEDEDAKLTKKHKKDKKEKKKRKKEKTEGQAQAEQPSCSRSATVKEKKDERASRKHSSKT 208
Query: 296 RDRDR--DHRED-RHHRDRDRNRDRDRGKERDRERDRGRDRERGRDRDRGRERDRDRERD 352
+R + +HRE + H R + D E +++ + + R ++ R+
Sbjct: 209 SERAQKSEHRESKKSHSGSPDGRSSYHARAEDPECKARKEKPKHEHKSASRREAEEKSRE 268
Query: 353 HERDVEHDRYREKDKDYEVGETDRGRSHDRGADYDHVESKHEKEPHGEIERDYEPDD--H 410
ER + + + + G + R RS R D H +H+K H Y D H
Sbjct: 269 RERGRSSGTHSGRHRGHSDGRSHRSRSRSRSPDKSH---RHKKYRHSRERDSYHGSDRRH 325
Query: 411 H 411
H
Sbjct: 326 H 326
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.313 0.135 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,411,640
Number of Sequences: 164201
Number of extensions: 3432394
Number of successful extensions: 35481
Number of sequences better than 10.0: 1359
Number of HSP's better than 10.0 without gapping: 781
Number of HSP's successfully gapped in prelim test: 611
Number of HSP's that attempted gapping in prelim test: 12610
Number of HSP's gapped (non-prelim): 7785
length of query: 502
length of database: 59,974,054
effective HSP length: 114
effective length of query: 388
effective length of database: 41,255,140
effective search space: 16006994320
effective search space used: 16006994320
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)
Medicago: description of AC148484.9