BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC148483.19 - phase: 0
(230 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
FL2_MOUSE (Q8BH16) F-box/LRR-repeat protein 2 (F-box and leucine... 54 4e-07
FL2_HUMAN (Q9UKC9) F-box/LRR-repeat protein 2 (F-box and leucine... 53 7e-07
FXLK_RAT (Q9QZH7) F-box/LRR-repeat protein 20 (F-box and leucine... 50 4e-06
FXLK_MOUSE (Q9CZV8) F-box/LRR-repeat protein 20 (F-box and leuci... 50 4e-06
FXLK_HUMAN (Q96IG2) F-box/LRR-repeat protein 20 (F-box and leuci... 50 4e-06
YKK7_CAEEL (P34284) Hypothetical F-box/LRR-repeat protein C02F5.... 49 1e-05
FXL7_HUMAN (Q9UJT9) F-box/LRR-repeat protein 7 (F-box and leucin... 48 2e-05
FXL4_HUMAN (Q9UKA2) F-box/LRR-repeat protein 4 (F-box and leucin... 44 2e-04
FX37_MOUSE (Q91W61) F-box only protein 37 (F-box/LRR-repeat prot... 43 7e-04
GRR1_YEAST (P24814) Ubiquitin ligase complex F-box protein GRR1 41 0.002
POF2_SCHPO (O74783) F-box/LRR-repeat protein 2 (F-box and leucin... 41 0.003
FXLE_MOUSE (Q8BID8) F-box/LRR-repeat protein 14 (F-box and leuci... 40 0.004
FXLE_HUMAN (Q8N1E6) F-box/LRR-repeat protein 14 (F-box and leuci... 40 0.004
FX37_HUMAN (Q9H469) F-box only protein 37 (F-box/LRR-repeat prot... 40 0.004
ESA8_TRYEQ (P26337) Putative adenylate cyclase regulatory protein 39 0.008
FXLG_HUMAN (Q8N461) F-box/LRR-repeat protein 16 (F-box and leuci... 38 0.023
YB08_YEAST (P38285) Hypothetical 62.7 kDa protein in CNS1-CDC28 ... 37 0.030
BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precurso... 37 0.030
SKP2_HUMAN (Q13309) S-phase kinase-associated protein 2 (F-box p... 37 0.039
ESA8_TRYBB (P23799) Putative adenylate cyclase regulatory protei... 37 0.039
>FL2_MOUSE (Q8BH16) F-box/LRR-repeat protein 2 (F-box and
leucine-rich repeat protein 2)
Length = 423
Score = 53.5 bits (127), Expect = 4e-07
Identities = 42/153 (27%), Positives = 74/153 (47%), Gaps = 10/153 (6%)
Query: 64 SNISDELLSSIATERLPLTRLVLQYCIGIVQ--VLGI---CCNIRHLNLSKCSMVKLEMN 118
+ I+D S++ L L L C+ + + GI C N+ +LNLS C + E
Sbjct: 115 TKITDSTCYSLSRFCSKLKHLDLTSCVSVTNSSLKGISEGCRNLEYLNLSWCDQITKEGI 174
Query: 119 FEVPK----LEVLNL-SYTNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCT 173
+ + L+ L L T ++DEAL I C L+ L+L++C+ T GV + C
Sbjct: 175 EALVRGCRGLKALLLRGCTQLEDEALKHIQNHCHELVSLNLQSCSRITDDGVVQICRGCH 234
Query: 174 QLRKISLDGCHKVHANIVSSMVSSRPSLRQITA 206
+L+ + L GC + ++++ + P L+ + A
Sbjct: 235 RLQALCLSGCSNLTDASLTALGLNCPRLQVLEA 267
Score = 52.4 bits (124), Expect = 9e-07
Identities = 37/113 (32%), Positives = 58/113 (50%), Gaps = 10/113 (8%)
Query: 81 LTRLVLQYCIGIVQ-----VLGICCNIRHLNLSKCSMVKLEMNFEV----PKLEVLNL-S 130
L +L L+ CIG+ C NI HLNL+ C+ + + + KL+ L+L S
Sbjct: 80 LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTS 139
Query: 131 YTNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCTQLRKISLDGC 183
+V + +L IS+ C L L+L C+ TK+G+ +V C L+ + L GC
Sbjct: 140 CVSVTNSSLKGISEGCRNLEYLNLSWCDQITKEGIEALVRGCRGLKALLLRGC 192
Score = 47.0 bits (110), Expect = 4e-05
Identities = 35/133 (26%), Positives = 62/133 (46%), Gaps = 10/133 (7%)
Query: 64 SNISDELLSSIATERLPLTRLVLQYCI-----GIVQVLGICCNIRHLNLSKCSMVK---- 114
+ + DE L I L L LQ C G+VQ+ C ++ L LS CS +
Sbjct: 193 TQLEDEALKHIQNHCHELVSLNLQSCSRITDDGVVQICRGCHRLQALCLSGCSNLTDASL 252
Query: 115 LEMNFEVPKLEVLNLSY-TNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCT 173
+ P+L+VL + +++ D +++++C L K+ LE C T + + +C
Sbjct: 253 TALGLNCPRLQVLEAARCSHLTDAGFTLLARNCHELEKMDLEECVLITDSTLVQLSIHCP 312
Query: 174 QLRKISLDGCHKV 186
+L+ +SL C +
Sbjct: 313 KLQALSLSHCELI 325
Score = 42.7 bits (99), Expect = 7e-04
Identities = 46/215 (21%), Positives = 90/215 (41%), Gaps = 32/215 (14%)
Query: 23 RSLSFSKTNGPVKVRYESAYTTSHFISSL--------------SLKCLA----SLDLLSS 64
R++ NG K+ + Y+ S F S L SLK ++ +L+ L+
Sbjct: 104 RNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVSVTNSSLKGISEGCRNLEYLNL 163
Query: 65 NISDEL----LSSIATERLPLTRLVLQYCI-----GIVQVLGICCNIRHLNLSKCSMVKL 115
+ D++ + ++ L L+L+ C + + C + LNL CS +
Sbjct: 164 SWCDQITKEGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNHCHELVSLNLQSCSRITD 223
Query: 116 EMNFEV----PKLEVLNLS-YTNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVE 170
+ ++ +L+ L LS +N+ D +L + +C L L C+ T G +
Sbjct: 224 DGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQVLEAARCSHLTDAGFTLLAR 283
Query: 171 NCTQLRKISLDGCHKVHANIVSSMVSSRPSLRQIT 205
NC +L K+ L+ C + + + + P L+ ++
Sbjct: 284 NCHELEKMDLEECVLITDSTLVQLSIHCPKLQALS 318
Score = 37.7 bits (86), Expect = 0.023
Identities = 19/56 (33%), Positives = 29/56 (50%), Gaps = 1/56 (1%)
Query: 132 TNVDDEALYMISKSCCGLL-KLSLENCNDFTKKGVNHVVENCTQLRKISLDGCHKV 186
T+V+ + ISK C G L KLSL C + +NC + ++L+GC K+
Sbjct: 62 TDVEGRVVENISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKI 117
>FL2_HUMAN (Q9UKC9) F-box/LRR-repeat protein 2 (F-box and
leucine-rich repeat protein 2) (F-box protein FBL2/FBL3)
Length = 423
Score = 52.8 bits (125), Expect = 7e-07
Identities = 42/153 (27%), Positives = 75/153 (48%), Gaps = 10/153 (6%)
Query: 64 SNISDELLSSIATERLPLTRLVLQYCIGIVQ--VLGI---CCNIRHLNLSKCSMVKLEMN 118
+ I+D S++ L L L C+ I + GI C N+ +LNLS C + +
Sbjct: 115 TKITDSTCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGI 174
Query: 119 FEVPK----LEVLNL-SYTNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCT 173
+ + L+ L L T ++DEAL I C L+ L+L++C+ T +GV + C
Sbjct: 175 EALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCH 234
Query: 174 QLRKISLDGCHKVHANIVSSMVSSRPSLRQITA 206
+L+ + L GC + ++++ + P L+ + A
Sbjct: 235 RLQALCLSGCSNLTDASLTALGLNCPRLQILEA 267
Score = 51.2 bits (121), Expect = 2e-06
Identities = 36/113 (31%), Positives = 57/113 (49%), Gaps = 10/113 (8%)
Query: 81 LTRLVLQYCIGIVQ-----VLGICCNIRHLNLSKCSMVKLEMNFEV----PKLEVLNL-S 130
L +L L+ CIG+ C NI HLNL+ C+ + + + KL+ L+L S
Sbjct: 80 LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTS 139
Query: 131 YTNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCTQLRKISLDGC 183
++ + +L IS+ C L L+L C+ TK G+ +V C L+ + L GC
Sbjct: 140 CVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGC 192
Score = 45.8 bits (107), Expect = 8e-05
Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 10/133 (7%)
Query: 64 SNISDELLSSIATERLPLTRLVLQYCI-----GIVQVLGICCNIRHLNLSKCSMVK---- 114
+ + DE L I L L LQ C G+VQ+ C ++ L LS CS +
Sbjct: 193 TQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASL 252
Query: 115 LEMNFEVPKLEVLNLSY-TNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCT 173
+ P+L++L + +++ D +++++C L K+ LE C T + + +C
Sbjct: 253 TALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCP 312
Query: 174 QLRKISLDGCHKV 186
+L+ +SL C +
Sbjct: 313 KLQALSLSHCELI 325
Score = 44.3 bits (103), Expect = 2e-04
Identities = 47/215 (21%), Positives = 90/215 (41%), Gaps = 32/215 (14%)
Query: 23 RSLSFSKTNGPVKVRYESAYTTSHFISSL--------------SLKCLA----SLDLLSS 64
R++ NG K+ + Y+ S F S L SLK ++ +L+ L+
Sbjct: 104 RNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNL 163
Query: 65 NISDEL----LSSIATERLPLTRLVLQYCI-----GIVQVLGICCNIRHLNLSKCSMVKL 115
+ D++ + ++ L L+L+ C + + C + LNL CS +
Sbjct: 164 SWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITD 223
Query: 116 EMNFEV----PKLEVLNLS-YTNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVE 170
E ++ +L+ L LS +N+ D +L + +C L L C+ T G +
Sbjct: 224 EGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLAR 283
Query: 171 NCTQLRKISLDGCHKVHANIVSSMVSSRPSLRQIT 205
NC +L K+ L+ C + + + + P L+ ++
Sbjct: 284 NCHELEKMDLEECILITDSTLIQLSIHCPKLQALS 318
Score = 35.8 bits (81), Expect = 0.087
Identities = 18/55 (32%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
Query: 133 NVDDEALYMISKSCCGLL-KLSLENCNDFTKKGVNHVVENCTQLRKISLDGCHKV 186
+V+ + ISK C G L KLSL C + +NC + ++L+GC K+
Sbjct: 63 DVEGRVVENISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKI 117
>FXLK_RAT (Q9QZH7) F-box/LRR-repeat protein 20 (F-box and
leucine-rich repeat protein 20) (F-box/LRR-repeat
protein 2-like)
Length = 276
Score = 50.1 bits (118), Expect = 4e-06
Identities = 34/136 (25%), Positives = 60/136 (44%), Gaps = 33/136 (24%)
Query: 99 CCNIRHLNLSKCSMVKLEMNFEV-----PKLEVLNLSY---------------------- 131
C +RHL+L+ C+ + M+ + P LE LN+S+
Sbjct: 142 CSKLRHLDLASCTSIT-NMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKAL 200
Query: 132 -----TNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCTQLRKISLDGCHKV 186
T ++DEAL I C L+ L+L+ C T +G+ + C +L+ + GC +
Sbjct: 201 FLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNI 260
Query: 187 HANIVSSMVSSRPSLR 202
I++++ + P LR
Sbjct: 261 TDAILNALGQNCPRLR 276
Score = 37.0 bits (84), Expect = 0.039
Identities = 21/82 (25%), Positives = 39/82 (46%), Gaps = 1/82 (1%)
Query: 124 LEVLNLS-YTNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCTQLRKISLDG 182
+EVL+L+ T D +SK C L L L +C T + + E C L ++++
Sbjct: 119 IEVLSLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISW 178
Query: 183 CHKVHANIVSSMVSSRPSLRQI 204
C +V + + ++V L+ +
Sbjct: 179 CDQVTKDGIQALVRGCGGLKAL 200
Score = 35.8 bits (81), Expect = 0.087
Identities = 21/73 (28%), Positives = 33/73 (44%), Gaps = 1/73 (1%)
Query: 133 NVDDEALYMISKSCCGLL-KLSLENCNDFTKKGVNHVVENCTQLRKISLDGCHKVHANIV 191
+++ + ISK C G L KLSL C + +NC + +SL+GC K
Sbjct: 76 DIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLSLNGCTKTTDATC 135
Query: 192 SSMVSSRPSLRQI 204
+S+ LR +
Sbjct: 136 TSLSKFCSKLRHL 148
Score = 33.1 bits (74), Expect = 0.56
Identities = 18/71 (25%), Positives = 32/71 (44%)
Query: 134 VDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCTQLRKISLDGCHKVHANIVSS 193
V D AL +++C + LSL C T + + C++LR + L C + + +
Sbjct: 104 VGDNALRTFAQNCRNIEVLSLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKA 163
Query: 194 MVSSRPSLRQI 204
+ P L Q+
Sbjct: 164 LSEGCPLLEQL 174
>FXLK_MOUSE (Q9CZV8) F-box/LRR-repeat protein 20 (F-box and
leucine-rich repeat protein 20) (F-box/LRR-repeat
protein 2-like)
Length = 436
Score = 50.1 bits (118), Expect = 4e-06
Identities = 34/136 (25%), Positives = 60/136 (44%), Gaps = 33/136 (24%)
Query: 99 CCNIRHLNLSKCSMVKLEMNFEV-----PKLEVLNLSY---------------------- 131
C +RHL+L+ C+ + M+ + P LE LN+S+
Sbjct: 142 CSKLRHLDLASCTSIT-NMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKAL 200
Query: 132 -----TNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCTQLRKISLDGCHKV 186
T ++DEAL I C L+ L+L+ C T +G+ + C +L+ + GC +
Sbjct: 201 FLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNI 260
Query: 187 HANIVSSMVSSRPSLR 202
I++++ + P LR
Sbjct: 261 TDAILNALGQNCPRLR 276
Score = 42.0 bits (97), Expect = 0.001
Identities = 44/184 (23%), Positives = 77/184 (40%), Gaps = 18/184 (9%)
Query: 14 KALRER-PTLRSLSFSKTNGPVKVRYESAYTTSHFISSLSLKCLASLDLLSSNISDELLS 72
KAL E P L L+ S + K ++ + +L LK L+ DE L
Sbjct: 162 KALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLE-------DEALK 214
Query: 73 SIATERLPLTRLVLQYCI-----GIVQVLGICCNIRHLNLSKCSMVK----LEMNFEVPK 123
I L L LQ C+ G++ + C ++ L S CS + + P+
Sbjct: 215 YIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPR 274
Query: 124 LEVLNLSY-TNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCTQLRKISLDG 182
L +L ++ + + D ++++C L K+ LE C T + + +C +L+ +SL
Sbjct: 275 LRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSH 334
Query: 183 CHKV 186
C +
Sbjct: 335 CELI 338
Score = 38.1 bits (87), Expect = 0.017
Identities = 50/195 (25%), Positives = 78/195 (39%), Gaps = 24/195 (12%)
Query: 4 CFDITFDGIAKALRERPTLRSLSFSKTNGPVKVRYESA-YTTSHFISSLSLKCLASLDLL 62
C +T DGI +R L++L G ++ E+ Y +H ++L L
Sbjct: 179 CDQVTKDGIQALVRGCGGLKALFLK---GCTQLEDEALKYIGAHCPELVTLNLQTCLQ-- 233
Query: 63 SSNISDELLSSIATERLPLTRLVLQYCIGIVQVL-----GICCNIRHLNLSKCSMVKLEM 117
I+DE L +I L L C I + C +R L +++CS + ++
Sbjct: 234 ---ITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLT-DV 289
Query: 118 NFEV-----PKLEVLNLSY-TNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVEN 171
F +LE ++L + D L +S C L LSL +C T G+ H+
Sbjct: 290 GFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNG 349
Query: 172 C---TQLRKISLDGC 183
QL I LD C
Sbjct: 350 ACAHDQLEVIELDNC 364
Score = 37.0 bits (84), Expect = 0.039
Identities = 21/82 (25%), Positives = 39/82 (46%), Gaps = 1/82 (1%)
Query: 124 LEVLNLS-YTNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCTQLRKISLDG 182
+EVL+L+ T D +SK C L L L +C T + + E C L ++++
Sbjct: 119 IEVLSLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISW 178
Query: 183 CHKVHANIVSSMVSSRPSLRQI 204
C +V + + ++V L+ +
Sbjct: 179 CDQVTKDGIQALVRGCGGLKAL 200
Score = 35.8 bits (81), Expect = 0.087
Identities = 21/73 (28%), Positives = 33/73 (44%), Gaps = 1/73 (1%)
Query: 133 NVDDEALYMISKSCCGLL-KLSLENCNDFTKKGVNHVVENCTQLRKISLDGCHKVHANIV 191
+++ + ISK C G L KLSL C + +NC + +SL+GC K
Sbjct: 76 DIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLSLNGCTKTTDATC 135
Query: 192 SSMVSSRPSLRQI 204
+S+ LR +
Sbjct: 136 TSLSKFCSKLRHL 148
Score = 33.1 bits (74), Expect = 0.56
Identities = 39/180 (21%), Positives = 76/180 (41%), Gaps = 25/180 (13%)
Query: 4 CFDITFDGIAKALRERPTLRSLSFSKTNGPVKVRYESAYTTSHFISSLSLKC--LASLDL 61
C IT +G+ R L+SL S + T +++L C L L++
Sbjct: 231 CLQITDEGLITICRGCHKLQSLCASGCSN----------ITDAILNALGQNCPRLRILEV 280
Query: 62 LS-SNISDELLSSIATERLPLTRLVLQYCIGI-----VQVLGICCNIRHLNLSKCSMVKL 115
S ++D +++A L ++ L+ C+ I +Q+ C ++ L+LS C ++
Sbjct: 281 ARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITD 340
Query: 116 EMNFEV-------PKLEVLNLSYTNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHV 168
+ + +LEV+ L + +A KSC ++ L +C T+ G+ +
Sbjct: 341 DGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLKSCPSFERIELYDCQQITRAGIKRL 400
Score = 33.1 bits (74), Expect = 0.56
Identities = 18/71 (25%), Positives = 32/71 (44%)
Query: 134 VDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCTQLRKISLDGCHKVHANIVSS 193
V D AL +++C + LSL C T + + C++LR + L C + + +
Sbjct: 104 VGDNALRTFAQNCRNIEVLSLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKA 163
Query: 194 MVSSRPSLRQI 204
+ P L Q+
Sbjct: 164 LSEGCPLLEQL 174
>FXLK_HUMAN (Q96IG2) F-box/LRR-repeat protein 20 (F-box and
leucine-rich repeat protein 20) (F-box/LRR-repeat
protein 2-like)
Length = 436
Score = 50.1 bits (118), Expect = 4e-06
Identities = 34/136 (25%), Positives = 60/136 (44%), Gaps = 33/136 (24%)
Query: 99 CCNIRHLNLSKCSMVKLEMNFEV-----PKLEVLNLSY---------------------- 131
C +RHL+L+ C+ + M+ + P LE LN+S+
Sbjct: 142 CSKLRHLDLASCTSIT-NMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKAL 200
Query: 132 -----TNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCTQLRKISLDGCHKV 186
T ++DEAL I C L+ L+L+ C T +G+ + C +L+ + GC +
Sbjct: 201 FLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNI 260
Query: 187 HANIVSSMVSSRPSLR 202
I++++ + P LR
Sbjct: 261 TDAILNALGQNCPRLR 276
Score = 42.0 bits (97), Expect = 0.001
Identities = 44/184 (23%), Positives = 77/184 (40%), Gaps = 18/184 (9%)
Query: 14 KALRER-PTLRSLSFSKTNGPVKVRYESAYTTSHFISSLSLKCLASLDLLSSNISDELLS 72
KAL E P L L+ S + K ++ + +L LK L+ DE L
Sbjct: 162 KALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLE-------DEALK 214
Query: 73 SIATERLPLTRLVLQYCI-----GIVQVLGICCNIRHLNLSKCSMVK----LEMNFEVPK 123
I L L LQ C+ G++ + C ++ L S CS + + P+
Sbjct: 215 YIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPR 274
Query: 124 LEVLNLSY-TNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCTQLRKISLDG 182
L +L ++ + + D ++++C L K+ LE C T + + +C +L+ +SL
Sbjct: 275 LRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSH 334
Query: 183 CHKV 186
C +
Sbjct: 335 CELI 338
Score = 38.9 bits (89), Expect = 0.010
Identities = 22/82 (26%), Positives = 39/82 (46%), Gaps = 1/82 (1%)
Query: 124 LEVLNLS-YTNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCTQLRKISLDG 182
+EVLNL+ T D +SK C L L L +C T + + E C L ++++
Sbjct: 119 IEVLNLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISW 178
Query: 183 CHKVHANIVSSMVSSRPSLRQI 204
C +V + + ++V L+ +
Sbjct: 179 CDQVTKDGIQALVRGCGGLKAL 200
Score = 38.1 bits (87), Expect = 0.017
Identities = 50/195 (25%), Positives = 78/195 (39%), Gaps = 24/195 (12%)
Query: 4 CFDITFDGIAKALRERPTLRSLSFSKTNGPVKVRYESA-YTTSHFISSLSLKCLASLDLL 62
C +T DGI +R L++L G ++ E+ Y +H ++L L
Sbjct: 179 CDQVTKDGIQALVRGCGGLKALFLK---GCTQLEDEALKYIGAHCPELVTLNLQTCLQ-- 233
Query: 63 SSNISDELLSSIATERLPLTRLVLQYCIGIVQVL-----GICCNIRHLNLSKCSMVKLEM 117
I+DE L +I L L C I + C +R L +++CS + ++
Sbjct: 234 ---ITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLT-DV 289
Query: 118 NFEV-----PKLEVLNLSY-TNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVEN 171
F +LE ++L + D L +S C L LSL +C T G+ H+
Sbjct: 290 GFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNG 349
Query: 172 C---TQLRKISLDGC 183
QL I LD C
Sbjct: 350 ACAHDQLEVIELDNC 364
Score = 34.7 bits (78), Expect = 0.19
Identities = 40/180 (22%), Positives = 77/180 (42%), Gaps = 25/180 (13%)
Query: 4 CFDITFDGIAKALRERPTLRSLSFSKTNGPVKVRYESAYTTSHFISSLSLKC--LASLDL 61
C IT +G+ R L+SL S + T +++L C L L++
Sbjct: 231 CLQITDEGLITICRGCHKLQSLCASGCSN----------ITDAILNALGQNCPRLRILEV 280
Query: 62 LS-SNISDELLSSIATERLPLTRLVLQYCIGI-----VQVLGICCNIRHLNLSKCSMVKL 115
S ++D +++A L ++ L+ C+ I +Q+ C ++ L+LS C ++
Sbjct: 281 ARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITD 340
Query: 116 EMNFEV-------PKLEVLNLSYTNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHV 168
+ + +LEV+ L + +A KSC L ++ L +C T+ G+ +
Sbjct: 341 DGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRL 400
Score = 34.7 bits (78), Expect = 0.19
Identities = 20/73 (27%), Positives = 33/73 (44%), Gaps = 1/73 (1%)
Query: 133 NVDDEALYMISKSCCGLL-KLSLENCNDFTKKGVNHVVENCTQLRKISLDGCHKVHANIV 191
+++ + ISK C G L KLSL C + +NC + ++L+GC K
Sbjct: 76 DIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATC 135
Query: 192 SSMVSSRPSLRQI 204
+S+ LR +
Sbjct: 136 TSLSKFCSKLRHL 148
Score = 32.0 bits (71), Expect = 1.3
Identities = 17/71 (23%), Positives = 32/71 (44%)
Query: 134 VDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCTQLRKISLDGCHKVHANIVSS 193
V D AL +++C + L+L C T + + C++LR + L C + + +
Sbjct: 104 VGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKA 163
Query: 194 MVSSRPSLRQI 204
+ P L Q+
Sbjct: 164 LSEGCPLLEQL 174
>YKK7_CAEEL (P34284) Hypothetical F-box/LRR-repeat protein C02F5.7
in chromosome III
Length = 461
Score = 48.9 bits (115), Expect = 1e-05
Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
Query: 99 CCNIRHLNLSKCSMVK----LEMNFEVPKLEVLNL-SYTNVDDEALYMISKSCCGLLKLS 153
C N+ HL+L +C V + KL LNL + +++ D A+ I C L L+
Sbjct: 148 CPNLEHLSLYRCKRVTDASCENLGRYCHKLNYLNLENCSSITDRAMKYIGDGCPNLSYLN 207
Query: 154 LENCNDFTKKGVNHVVENCTQLRKISLDGCHKVHANIVSSMVSSRPSLRQI 204
+ C+ +GV ++ NC L + L GC + N+ S+ + +++++
Sbjct: 208 ISWCDAIQDRGVQIILSNCKSLDTLILRGCEGLTENVFGSVEAHMGAIKKL 258
Score = 45.8 bits (107), Expect = 8e-05
Identities = 34/153 (22%), Positives = 68/153 (44%), Gaps = 14/153 (9%)
Query: 58 SLDLL----SSNISDELLSSIATERLPLTRLVLQYC-----IGIVQVLGICCNIRHLNLS 108
SLD L +++ + S+ + +L L C I + + + +L +S
Sbjct: 228 SLDTLILRGCEGLTENVFGSVEAHMGAIKKLNLLQCFQLTDITVQNIANGATALEYLCMS 287
Query: 109 KCSMVK----LEMNFEVPKLEVLNLS-YTNVDDEALYMISKSCCGLLKLSLENCNDFTKK 163
C+ + + + L+VL LS T + D +++ C L +L +E+C+ +
Sbjct: 288 NCNQISDRSLVSLGQHSHNLKVLELSGCTLLGDNGFIPLARGCRQLERLDMEDCSLISDH 347
Query: 164 GVNHVVENCTQLRKISLDGCHKVHANIVSSMVS 196
+N + NCT LR++SL C + + ++ S
Sbjct: 348 TINSLANNCTALRELSLSHCELITDESIQNLAS 380
Score = 38.1 bits (87), Expect = 0.017
Identities = 33/150 (22%), Positives = 64/150 (42%), Gaps = 10/150 (6%)
Query: 66 ISDELLSSIATERLPLTRLVLQYCIGIVQ-----VLGICCNIRHLNLSKC----SMVKLE 116
I D + I + L L+L+ C G+ + V I+ LNL +C +
Sbjct: 214 IQDRGVQIILSNCKSLDTLILRGCEGLTENVFGSVEAHMGAIKKLNLLQCFQLTDITVQN 273
Query: 117 MNFEVPKLEVLNLSYTN-VDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCTQL 175
+ LE L +S N + D +L + + L L L C G + C QL
Sbjct: 274 IANGATALEYLCMSNCNQISDRSLVSLGQHSHNLKVLELSGCTLLGDNGFIPLARGCRQL 333
Query: 176 RKISLDGCHKVHANIVSSMVSSRPSLRQIT 205
++ ++ C + + ++S+ ++ +LR+++
Sbjct: 334 ERLDMEDCSLISDHTINSLANNCTALRELS 363
Score = 33.5 bits (75), Expect = 0.43
Identities = 28/101 (27%), Positives = 49/101 (47%), Gaps = 13/101 (12%)
Query: 117 MNFEVPKLEVLNLSYTNVDDEALYMISKSCCGLLKLSLENCN-------DFTKKGVNHVV 169
+N +PK EVL ++ +D +AL ++ C L+L+ N F + VV
Sbjct: 56 INRVLPK-EVLLKVFSFLDTKALCRSAQVCRSWSILALDGSNWQRVDLFTFQRDVKTAVV 114
Query: 170 ENCTQ-----LRKISLDGCHKVHANIVSSMVSSRPSLRQIT 205
EN + L+++SL GC VH + + + S P+L ++
Sbjct: 115 ENLARRCGGFLKELSLKGCENVHDSALRTFTSRCPNLEHLS 155
Score = 32.3 bits (72), Expect = 0.96
Identities = 18/69 (26%), Positives = 29/69 (41%)
Query: 133 NVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCTQLRKISLDGCHKVHANIVS 192
NV D AL + C L LSL C T ++ C +L ++L+ C + +
Sbjct: 135 NVHDSALRTFTSRCPNLEHLSLYRCKRVTDASCENLGRYCHKLNYLNLENCSSITDRAMK 194
Query: 193 SMVSSRPSL 201
+ P+L
Sbjct: 195 YIGDGCPNL 203
>FXL7_HUMAN (Q9UJT9) F-box/LRR-repeat protein 7 (F-box and
leucine-rich repeat protein 7) (F-box protein FBL6/FBL7)
Length = 491
Score = 48.1 bits (113), Expect = 2e-05
Identities = 51/222 (22%), Positives = 89/222 (39%), Gaps = 41/222 (18%)
Query: 4 CFDITFDGIAKALRERPTLRSLSFS---KTNGPVKVRYESAYTTSHFISSLSLKCLASLD 60
C++I+ + + + P L L S K R S + +S++ L D
Sbjct: 222 CYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTD 281
Query: 61 LLSSNISDELLSSIATERLPLTRLVLQYCI-----GIVQVLGICCNIRHLNLSKCSMVKL 115
+ DE L +IA LT L L+ C+ G+ ++ C +I+ L++S C V
Sbjct: 282 CFV--LEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSD 339
Query: 116 EMNFEVPKLE----VLNLSYTN-VDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVE 170
E+ KLE L++++ V D + ++K C L L+ C T GV ++ +
Sbjct: 340 FGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAK 399
Query: 171 NCTQLR--------------------------KISLDGCHKV 186
NCT+L+ ++SL C +
Sbjct: 400 NCTKLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLKSCESI 441
Score = 46.6 bits (109), Expect = 5e-05
Identities = 40/153 (26%), Positives = 68/153 (44%), Gaps = 13/153 (8%)
Query: 44 TSHFISSLSLKCLASLDLLSSN---ISDELLSSIATERLPLTRLVLQYC-----IGIVQV 95
T + L + C + +L S+ +SD L IA L L + +C +GI V
Sbjct: 312 TDEGLRYLVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYV 371
Query: 96 LGICCNIRHLNLSKCSMVKLE----MNFEVPKLEVLNLSYTN-VDDEALYMISKSCCGLL 150
C +R+LN C + + KL+ L++ V D L ++ +C L
Sbjct: 372 AKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFNLK 431
Query: 151 KLSLENCNDFTKKGVNHVVENCTQLRKISLDGC 183
+LSL++C T +G+ V NC L+ +++ C
Sbjct: 432 RLSLKSCESITGQGLQIVAANCFDLQTLNVQDC 464
Score = 39.3 bits (90), Expect = 0.008
Identities = 39/184 (21%), Positives = 68/184 (36%), Gaps = 47/184 (25%)
Query: 91 GIVQVLGICCNIRHLNLSKCSMVKLEMNFEV----PKLEVLNLSYTN------------- 133
G+ + C +R L +S C + E F+V P LE L++S +
Sbjct: 203 GLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTREASI 262
Query: 134 ----------------------VDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVEN 171
++DE L+ I+ C L L L C T +G+ ++V
Sbjct: 263 KLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVIY 322
Query: 172 CTQLRKISLDGCHKVHANIVSSMVSSRPSLR--------QITAPPTRTGAFSARKVKYFL 223
C ++++S+ C V + + LR ++T R A K++Y
Sbjct: 323 CASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLN 382
Query: 224 RQGC 227
+GC
Sbjct: 383 ARGC 386
Score = 37.7 bits (86), Expect = 0.023
Identities = 15/59 (25%), Positives = 31/59 (52%)
Query: 146 CCGLLKLSLENCNDFTKKGVNHVVENCTQLRKISLDGCHKVHANIVSSMVSSRPSLRQI 204
C L +++ C T +G+ + + C +LR++ + GC+ + V +VS P+L +
Sbjct: 185 CLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHL 243
>FXL4_HUMAN (Q9UKA2) F-box/LRR-repeat protein 4 (F-box and
leucine-rich repeat protein 4) (F-box protein FBL4/FBL5)
Length = 621
Score = 44.3 bits (103), Expect = 2e-04
Identities = 43/199 (21%), Positives = 78/199 (38%), Gaps = 36/199 (18%)
Query: 27 FSKTNGPVKVRYESAYTTSHFISSLSLKC------------LASLDLLSSNISDELLSSI 74
F K G VR E + SHF++ L+ L+S D L + +
Sbjct: 369 FLKVCGSELVRLE--LSCSHFLNETCLEVISEMCPNLQALNLSSCDKLPPQAFNHIAKLC 426
Query: 75 ATERLPLTRLVLQYCIGIVQVLGICCNIRHLNLSKCSMVKLEMNFEVPKLEVLNLSYTNV 134
+ +RL L R ++ ++ +L C ++HL+L C M++ Y
Sbjct: 427 SLKRLVLYRTKVEQT-ALLSILNFCSELQHLSLGSCVMIE---------------DY--- 467
Query: 135 DDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCTQLRKISLDGCHKVHAN--IVS 192
D MI C L L L C + T+ G+ + C L ++ L C + ++ +
Sbjct: 468 -DVIASMIGAKCKKLRTLDLWRCKNITENGIAELASGCPLLEELDLGWCPTLQSSTGCFT 526
Query: 193 SMVSSRPSLRQITAPPTRT 211
+ P+L+++ R+
Sbjct: 527 RLAHQLPNLQKLFLTANRS 545
>FX37_MOUSE (Q91W61) F-box only protein 37 (F-box/LRR-repeat protein
15)
Length = 296
Score = 42.7 bits (99), Expect = 7e-04
Identities = 41/150 (27%), Positives = 67/150 (44%), Gaps = 11/150 (7%)
Query: 66 ISDELLSSIATERLPLTRLVLQYCIGIVQ-VLGI----CCNIRHLNLSKCSMVK----LE 116
+SDE L + L + L C + + LG C ++ L+L+ C V
Sbjct: 97 LSDEDLVPVLARNPQLRSVALAGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRG 156
Query: 117 MNFEVPKLEVLNLSYTN-VDDEAL-YMISKSCCGLLKLSLENCNDFTKKGVNHVVENCTQ 174
+ P LE L+L+ + DEA+ Y+ + GL LSL + V + NC Q
Sbjct: 157 LADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDTAVQELARNCPQ 216
Query: 175 LRKISLDGCHKVHANIVSSMVSSRPSLRQI 204
L + L GC +V ++ V ++ P+LR +
Sbjct: 217 LEHLDLTGCLRVGSDGVRTLAEYCPALRSL 246
Score = 40.0 bits (92), Expect = 0.005
Identities = 35/132 (26%), Positives = 58/132 (43%), Gaps = 11/132 (8%)
Query: 66 ISDELLSSIATERLPLTRLVLQYC-----IGIVQVLGICCNIRHLNLSKCSMVKLEMNFE 120
+S L ++A L RL L +C + + + C + L+L+ C +K E
Sbjct: 123 LSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVY 182
Query: 121 VPK-----LEVLNLSYT-NVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCTQ 174
+ + L L+L+ NV D A+ ++++C L L L C GV + E C
Sbjct: 183 LAQRRGAGLRSLSLAVNANVGDTAVQELARNCPQLEHLDLTGCLRVGSDGVRTLAEYCPA 242
Query: 175 LRKISLDGCHKV 186
LR + + CH V
Sbjct: 243 LRSLRVRHCHHV 254
>GRR1_YEAST (P24814) Ubiquitin ligase complex F-box protein GRR1
Length = 1151
Score = 41.2 bits (95), Expect = 0.002
Identities = 44/215 (20%), Positives = 90/215 (41%), Gaps = 27/215 (12%)
Query: 6 DITFDGIAKALRERPTLRSLSFSKTNGPVKVRYESAYTTSHFISSLSLKC--LASLDL-L 62
++TFD + + P L+ + + N + L+ KC L +D+ L
Sbjct: 478 NVTFDSLRNFIVHSPMLKRIKITANNN----------MNDELVELLANKCPLLVEVDITL 527
Query: 63 SSNISDELLSSIATERLPLTRLVLQYCIGIV--------QVLGICCNIRHLNLSKCSMVK 114
S N++D L + T + L + + I +V+ ++R ++LS C +
Sbjct: 528 SPNVTDSSLLKLLTRLVQLREFRITHNTNITDNLFQELSKVVDDMPSLRLIDLSGCENIT 587
Query: 115 LEMNFEV----PKLEVLNLSY-TNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVV 169
+ + PKL + L + + D +L+ +SK L + +C + T GV +
Sbjct: 588 DKTIESIVNLAPKLRNVFLGKCSRITDASLFQLSKLGKNLQTVHFGHCFNITDNGVRALF 647
Query: 170 ENCTQLRKISLDGCHKVHANIVSSMVSSRPSLRQI 204
+CT+++ + C + N ++ P L++I
Sbjct: 648 HSCTRIQYVDFACCTNL-TNRTLYELADLPKLKRI 681
>POF2_SCHPO (O74783) F-box/LRR-repeat protein 2 (F-box and
leucine-rich repeat protein 2) (F-box protein pof2)
Length = 463
Score = 40.8 bits (94), Expect = 0.003
Identities = 50/213 (23%), Positives = 90/213 (41%), Gaps = 43/213 (20%)
Query: 28 SKTNGPVKVRYESAYTTSHFISSLSLKC-LASLDLLSSN--------------------- 65
S+ G ++ + SHFI+ L+L C L ++ LS N
Sbjct: 221 SRNRGLKELSMDGCTELSHFITFLNLNCELDAMRALSLNNLPDLKDSDIELITCKFSKLN 280
Query: 66 ---------ISDELLSSIATERLPLTRLVLQYC-----IGIVQVLGICCNIRHLNLSKC- 110
++D L S+ LT L L +C IG+ +L C NI +++ C
Sbjct: 281 SLFLSKCIGLTDSSLLSLTKLSQSLTTLHLGHCYEITDIGVQCLLKSCKNITYIDFGGCL 340
Query: 111 --SMVKLEMNFEVPKLEVLNL-SYTNVDDEALYMISKSCC-GLLKLSLENCNDFTKKGVN 166
S + + ++P L+ + L + D ++ ++S S L ++ L C T K V+
Sbjct: 341 RLSDIAVSAIAKLPYLQRVGLVKCICLTDLSVILLSGSFSRNLERVHLSYCIGLTAKSVS 400
Query: 167 HVVENCTQLRKISLDGCHKVHANIVSSMVSSRP 199
+++ NC L+ +S+ G + + + S SRP
Sbjct: 401 YLMYNCKTLKHLSVTGINSILCTELRSF--SRP 431
Score = 37.7 bits (86), Expect = 0.023
Identities = 21/99 (21%), Positives = 48/99 (48%), Gaps = 5/99 (5%)
Query: 93 VQVLGICCNIRHLNLSKCSMVKLEMNFEV--PKLEVLNLSYTNVDD---EALYMISKSCC 147
+ ++ + I LNLS C+ + + ++ L ++ ++++N+ L IS +C
Sbjct: 87 LMLMTLATGISRLNLSGCTRISEPLIGKLLYQNLNLVTINFSNIFSLPANILEYISDNCP 146
Query: 148 GLLKLSLENCNDFTKKGVNHVVENCTQLRKISLDGCHKV 186
L L++ NC G+ +++ C L ++ + C K+
Sbjct: 147 NLKALNIGNCGLVEDTGMVQIIKRCPYLNRLIIPNCRKL 185
Score = 35.8 bits (81), Expect = 0.087
Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 3/86 (3%)
Query: 122 PKLEVLNLSYTN-VDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCTQLRKISL 180
P L+ LN+ V+D + I K C L +L + NC T + ++ L ++ +
Sbjct: 146 PNLKALNIGNCGLVEDTGMVQIIKRCPYLNRLIIPNCRKLTDVSL-QILSEKEDLIELDI 204
Query: 181 DGCHKVH-ANIVSSMVSSRPSLRQIT 205
GC H A+ +S +VS L++++
Sbjct: 205 SGCEGFHNADTLSRLVSRNRGLKELS 230
>FXLE_MOUSE (Q8BID8) F-box/LRR-repeat protein 14 (F-box and
leucine-rich repeat protein 14)
Length = 400
Score = 40.4 bits (93), Expect = 0.004
Identities = 48/194 (24%), Positives = 84/194 (42%), Gaps = 14/194 (7%)
Query: 4 CFDITFDGIAKALRERPTLRSLSFSKTN--GPVKVRYESAYTTSHFISSLSLKCLASLDL 61
C +IT G+ L+SL+ V + + + T S L L+ L D
Sbjct: 153 CSNITNTGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEGCLGLEQLTLQDC 212
Query: 62 LSSNISDELLSSIATERLPLTRLVLQYCIGIVQV----LGICCNIRHLNLSKCSMVK--- 114
++D L I+ L L L +C GI L ++R LNL C +
Sbjct: 213 --QKLTDLSLKHISRGLTGLRLLNLSFCGGISDAGLLHLSHMGSLRSLNLRSCDNISDTG 270
Query: 115 -LEMNFEVPKLEVLNLSYTN-VDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENC 172
+ + +L L++S+ + V D++L I++ GL LSL +C+ + G+N +V
Sbjct: 271 IMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDGLKSLSLCSCH-ISDDGINRMVRQM 329
Query: 173 TQLRKISLDGCHKV 186
LR +++ C ++
Sbjct: 330 HGLRTLNIGQCVRI 343
Score = 38.9 bits (89), Expect = 0.010
Identities = 46/219 (21%), Positives = 93/219 (42%), Gaps = 24/219 (10%)
Query: 4 CFDITFDGIAKA-LRERPTLRSLSFSKTNGPVKVRYESAYTTSHFISSLSLKCLASLDLL 62
C+++T +G+ A ++E +LR+L+ S ++ S + ++ L + L
Sbjct: 100 CYNLTDNGLGHAFVQEIGSLRALNLSLCK---QITDSSLGRIAQYLKGLEVLELGGC--- 153
Query: 63 SSNISDELLSSIATERLPLTRLVLQYC-----IGIVQVLGI-------CCNIRHLNLSKC 110
SNI++ L IA L L L+ C +GI + G+ C + L L C
Sbjct: 154 -SNITNTGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEGCLGLEQLTLQDC 212
Query: 111 SMVK----LEMNFEVPKLEVLNLSYTNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVN 166
+ ++ + L +LNLS+ +A + L L+L +C++ + G+
Sbjct: 213 QKLTDLSLKHISRGLTGLRLLNLSFCGGISDAGLLHLSHMGSLRSLNLRSCDNISDTGIM 272
Query: 167 HVVENCTQLRKISLDGCHKVHANIVSSMVSSRPSLRQIT 205
H+ +L + + C KV ++ + L+ ++
Sbjct: 273 HLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDGLKSLS 311
Score = 37.4 bits (85), Expect = 0.030
Identities = 33/132 (25%), Positives = 59/132 (44%), Gaps = 18/132 (13%)
Query: 56 LASLDLLS-SNISDELLSSIATERLPLTRLVLQYCIGIVQVLGICCNIRHLNLSKCSMVK 114
L SL+L S NISD + +A L L+ L + +C + S+
Sbjct: 255 LRSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKV---------------GDQSLAY 299
Query: 115 LEMNFEVPKLEVLNLSYTNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCTQ 174
+ + L+ L+L ++ D+ + + + GL L++ C T KG+ + E+ +Q
Sbjct: 300 IAQGLD--GLKSLSLCSCHISDDGINRMVRQMHGLRTLNIGQCVRITDKGLELIAEHLSQ 357
Query: 175 LRKISLDGCHKV 186
L I L GC ++
Sbjct: 358 LTGIDLYGCTRI 369
>FXLE_HUMAN (Q8N1E6) F-box/LRR-repeat protein 14 (F-box and
leucine-rich repeat protein 14)
Length = 418
Score = 40.4 bits (93), Expect = 0.004
Identities = 48/194 (24%), Positives = 84/194 (42%), Gaps = 14/194 (7%)
Query: 4 CFDITFDGIAKALRERPTLRSLSFSKTN--GPVKVRYESAYTTSHFISSLSLKCLASLDL 61
C +IT G+ L+SL+ V + + + T S L L+ L D
Sbjct: 153 CSNITNTGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEGCLGLEQLTLQDC 212
Query: 62 LSSNISDELLSSIATERLPLTRLVLQYCIGIVQV----LGICCNIRHLNLSKCSMVK--- 114
++D L I+ L L L +C GI L ++R LNL C +
Sbjct: 213 --QKLTDLSLKHISRGLTGLRLLNLSFCGGISDAGLLHLSHMGSLRSLNLRSCDNISDTG 270
Query: 115 -LEMNFEVPKLEVLNLSYTN-VDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENC 172
+ + +L L++S+ + V D++L I++ GL LSL +C+ + G+N +V
Sbjct: 271 IMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDGLKSLSLCSCH-ISDDGINRMVRQM 329
Query: 173 TQLRKISLDGCHKV 186
LR +++ C ++
Sbjct: 330 HGLRTLNIGQCVRI 343
Score = 38.9 bits (89), Expect = 0.010
Identities = 46/219 (21%), Positives = 93/219 (42%), Gaps = 24/219 (10%)
Query: 4 CFDITFDGIAKA-LRERPTLRSLSFSKTNGPVKVRYESAYTTSHFISSLSLKCLASLDLL 62
C+++T +G+ A ++E +LR+L+ S ++ S + ++ L + L
Sbjct: 100 CYNLTDNGLGHAFVQEIGSLRALNLSLCK---QITDSSLGRIAQYLKGLEVLELGGC--- 153
Query: 63 SSNISDELLSSIATERLPLTRLVLQYC-----IGIVQVLGI-------CCNIRHLNLSKC 110
SNI++ L IA L L L+ C +GI + G+ C + L L C
Sbjct: 154 -SNITNTGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEGCLGLEQLTLQDC 212
Query: 111 SMVK----LEMNFEVPKLEVLNLSYTNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVN 166
+ ++ + L +LNLS+ +A + L L+L +C++ + G+
Sbjct: 213 QKLTDLSLKHISRGLTGLRLLNLSFCGGISDAGLLHLSHMGSLRSLNLRSCDNISDTGIM 272
Query: 167 HVVENCTQLRKISLDGCHKVHANIVSSMVSSRPSLRQIT 205
H+ +L + + C KV ++ + L+ ++
Sbjct: 273 HLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDGLKSLS 311
Score = 37.4 bits (85), Expect = 0.030
Identities = 33/132 (25%), Positives = 59/132 (44%), Gaps = 18/132 (13%)
Query: 56 LASLDLLS-SNISDELLSSIATERLPLTRLVLQYCIGIVQVLGICCNIRHLNLSKCSMVK 114
L SL+L S NISD + +A L L+ L + +C + S+
Sbjct: 255 LRSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKV---------------GDQSLAY 299
Query: 115 LEMNFEVPKLEVLNLSYTNVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCTQ 174
+ + L+ L+L ++ D+ + + + GL L++ C T KG+ + E+ +Q
Sbjct: 300 IAQGLD--GLKSLSLCSCHISDDGINRMVRQMHGLRTLNIGQCVRITDKGLELIAEHLSQ 357
Query: 175 LRKISLDGCHKV 186
L I L GC ++
Sbjct: 358 LTGIDLYGCTRI 369
>FX37_HUMAN (Q9H469) F-box only protein 37 (F-box/LRR-repeat protein
15)
Length = 296
Score = 40.4 bits (93), Expect = 0.004
Identities = 36/140 (25%), Positives = 62/140 (43%), Gaps = 11/140 (7%)
Query: 66 ISDELLSSIATERLPLTRLVLQYC-----IGIVQVLGICCNIRHLNLSKCSMVKLEMNFE 120
+S L ++A L RL L +C + + + C + L+L+ C +K E
Sbjct: 123 LSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVY 182
Query: 121 VPK-----LEVLNLSYT-NVDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCTQ 174
+ + L L+L+ NV D A+ ++++C L L L C GV + E C
Sbjct: 183 LAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPV 242
Query: 175 LRKISLDGCHKVHANIVSSM 194
LR + + CH V + +S +
Sbjct: 243 LRSLRVRHCHHVAESSLSRL 262
Score = 40.0 bits (92), Expect = 0.005
Identities = 31/112 (27%), Positives = 52/112 (45%), Gaps = 6/112 (5%)
Query: 99 CCNIRHLNLSKCSMVK----LEMNFEVPKLEVLNLSYTN-VDDEAL-YMISKSCCGLLKL 152
C ++ L+L+ C V + P LE L+L+ + DEA+ Y+ + GL L
Sbjct: 135 CPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSL 194
Query: 153 SLENCNDFTKKGVNHVVENCTQLRKISLDGCHKVHANIVSSMVSSRPSLRQI 204
SL + V + NC +L + L GC +V ++ V ++ P LR +
Sbjct: 195 SLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSL 246
Score = 30.4 bits (67), Expect = 3.6
Identities = 15/71 (21%), Positives = 33/71 (46%)
Query: 134 VDDEALYMISKSCCGLLKLSLENCNDFTKKGVNHVVENCTQLRKISLDGCHKVHANIVSS 193
+ DE L + L ++L C +++ + + E C +L+++SL C V +
Sbjct: 97 LSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRG 156
Query: 194 MVSSRPSLRQI 204
+ P+L ++
Sbjct: 157 LADRCPALEEL 167
Score = 29.3 bits (64), Expect = 8.1
Identities = 16/69 (23%), Positives = 38/69 (54%), Gaps = 1/69 (1%)
Query: 138 ALYMISKSCCGLLKLSLENCNDF-TKKGVNHVVENCTQLRKISLDGCHKVHANIVSSMVS 196
AL + + GL +L+L C+++ + + + V+ QLR ++L GC ++ + ++
Sbjct: 74 ALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAE 133
Query: 197 SRPSLRQIT 205
P L++++
Sbjct: 134 GCPRLQRLS 142
>ESA8_TRYEQ (P26337) Putative adenylate cyclase regulatory protein
Length = 630
Score = 39.3 bits (90), Expect = 0.008
Identities = 40/143 (27%), Positives = 65/143 (44%), Gaps = 15/143 (10%)
Query: 51 LSLKCLASLDLLSSNISDELLSSIATERLPLTRLVLQYCIGIVQVLGICC--NIRHLNLS 108
L+L+ L L + + ++D SSI + L L + G+ + G+C + L+L
Sbjct: 156 LTLRNLRKLRMKRTMVNDMWCSSIGLLKF-LVHLEVDGSRGVTDITGLCRLKTLEALSLD 214
Query: 109 KCSMVKLEMNFE----VPKLEVLNLSYTNVDDEALYMISKSCCGLLK-LSLENCNDFTKK 163
C + + F+ +P+L L+L TNV D+ L I G LK L +C++ T
Sbjct: 215 SC--INITKGFDKICALPQLTSLSLCQTNVTDKDLRCIHPD--GKLKVLRYSSCHEITDL 270
Query: 164 GVNHVVENCTQLRKISLDGCHKV 186
+ L K+SL GC V
Sbjct: 271 ---TAIGGMRSLEKLSLSGCWNV 290
>FXLG_HUMAN (Q8N461) F-box/LRR-repeat protein 16 (F-box and
leucine-rich repeat protein 16) (cg14134)
Length = 479
Score = 37.7 bits (86), Expect = 0.023
Identities = 26/118 (22%), Positives = 57/118 (48%), Gaps = 14/118 (11%)
Query: 88 YCIGIVQVLGICCNIRHLNLSKCSMVKLEMNFEVPKLEVLNLSYTNVDDEALYMISKSCC 147
+C+ V L IC I + LSK + + ++L + + D L ++ +
Sbjct: 171 FCLVGVSDLDICEFIDNYALSKKGV------------KAMSLKRSTITDAGLEVMLEQMQ 218
Query: 148 GLLKLSLENCNDFTKKGVNHVVENCTQLRKISLDGCHKVHANIVSSMVSSRPSLRQIT 205
G+++L L CNDFT+ G+ + ++ +S+ C V + ++++ P+L +++
Sbjct: 219 GVVRLELSGCNDFTEAGLWSSLS--ARITSLSVSDCINVADDAIAAISQLLPNLAELS 274
Score = 37.0 bits (84), Expect = 0.039
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 13/119 (10%)
Query: 1 MLHCFDITFDGIAKALRERPTLRSLSFSKTNGPVKVRYESAYTTSHFISSLSLKCLASLD 60
+L C++IT G+ + P L +LS S G KV + + +L+ L SLD
Sbjct: 301 LLSCWEITNHGVVNVVHSLPNLTALSLS---GCSKVTDDGVELVAE-----NLRKLRSLD 352
Query: 61 L-LSSNISDELLSSIATERLPLTRLVLQYCIGI----VQVLGICCNIRHLNLSKCSMVK 114
L I+D L +A + L LVL C+ I + L ++R L L C V+
Sbjct: 353 LSWCPRITDMALEYVACDLHRLEELVLDRCVRITDTGLSYLSTMSSLRSLYLRWCCQVQ 411
Score = 36.2 bits (82), Expect = 0.066
Identities = 42/171 (24%), Positives = 67/171 (38%), Gaps = 34/171 (19%)
Query: 50 SLSLKCLASLDLLSSNISDELLSSIATERLPLTRLVLQYCIGIVQV---LGICCNIRHLN 106
+LS K + ++ L S I+D L + + + RL L C + + I L+
Sbjct: 189 ALSKKGVKAMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSARITSLS 248
Query: 107 LSKCSMVKLE----MNFEVPKLEVLNLSYTNVDDEAL-YMISK----------------- 144
+S C V + ++ +P L L+L +V D AL Y ++
Sbjct: 249 VSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEIT 308
Query: 145 ---------SCCGLLKLSLENCNDFTKKGVNHVVENCTQLRKISLDGCHKV 186
S L LSL C+ T GV V EN +LR + L C ++
Sbjct: 309 NHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRI 359
>YB08_YEAST (P38285) Hypothetical 62.7 kDa protein in CNS1-CDC28
intergenic region
Length = 549
Score = 37.4 bits (85), Expect = 0.030
Identities = 27/99 (27%), Positives = 51/99 (51%), Gaps = 5/99 (5%)
Query: 99 CCNIRHLNLSKCSMVKLEMNF--EVPKLEVLNL-SYTNVDDEALYMISKSCCGLLKLSLE 155
C N++ L C + +++ + KLE L + N+DD L +S+S L L L
Sbjct: 311 CQNLKWLEFYVCPRITPPLSWFDNLHKLEKLIIPGNKNIDDNFLLRLSQSIPNLKHLVLR 370
Query: 156 NCNDFTKKGVNHVVENCTQLRKISLDGCHKVHANIVSSM 194
C++ + GV + NC +L+ ++ G H+ N+++S+
Sbjct: 371 ACDNVSDSGVVCIALNCPKLKTFNI-GRHR-RGNLITSV 407
>BRI1_LYCES (Q8GUQ5) Brassinosteroid LRR receptor kinase precursor
(EC 2.7.1.37) (tBRI1) (Altered brassinolide sensitivity
1) (Systemin receptor SR160)
Length = 1207
Score = 37.4 bits (85), Expect = 0.030
Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 9/99 (9%)
Query: 51 LSLKCLASLDLLSSNISDELLSS------IATERLPLTRLVLQYCIGIVQVLGICCNIRH 104
L L L SL L ++N+S L S+ + + + L + I + G+C N++
Sbjct: 105 LPLSNLESLVLKNANLSGSLTSAAKSQCGVTLDSIDLAENTISGPISDISSFGVCSNLKS 164
Query: 105 LNLSKCSM---VKLEMNFEVPKLEVLNLSYTNVDDEALY 140
LNLSK + K + L+VL+LSY N+ L+
Sbjct: 165 LNLSKNFLDPPGKEMLKAATFSLQVLDLSYNNISGFNLF 203
>SKP2_HUMAN (Q13309) S-phase kinase-associated protein 2 (F-box
protein Skp2) (Cyclin A/CDK2-associated protein p45)
(p45skp2) (F-box/LRR-repeat protein 1)
Length = 424
Score = 37.0 bits (84), Expect = 0.039
Identities = 56/202 (27%), Positives = 78/202 (37%), Gaps = 36/202 (17%)
Query: 8 TFDGIAKALRERPTLRSLSFSKTNGPVKVRYESAYTTSHFISSLSLKCLASLDLLSSNIS 67
T D K L T R LS G + R ++ S + +DL +S I
Sbjct: 139 TLDLTGKNLHPDVTGRLLS----QGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIE 194
Query: 68 DELLSSIATERLPLTRLVLQ---YCIGIVQVLGICCNIRHLNLSKCSMVKLEMNFEVPKL 124
L I ++ L L L+ IV L N+ LNLS CS
Sbjct: 195 VSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCS------------- 241
Query: 125 EVLNLSYTNVDDEALYMISKSCCGLLKLSLENCNDFTKK----GVNHVVENCTQLRKISL 180
+ AL + SC L +L+L C DFT+K V HV E TQL +L
Sbjct: 242 --------GFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQL---NL 290
Query: 181 DGCHK-VHANIVSSMVSSRPSL 201
G K + + +S++V P+L
Sbjct: 291 SGYRKNLQKSDLSTLVRRCPNL 312
>ESA8_TRYBB (P23799) Putative adenylate cyclase regulatory protein
(Leucine repeat protein) (VSG expression site-associated
protein F14.9)
Length = 630
Score = 37.0 bits (84), Expect = 0.039
Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 15/143 (10%)
Query: 51 LSLKCLASLDLLSSNISDELLSSIATERLPLTRLVLQYCIGIVQVLGI--CCNIRHLNLS 108
L+L+ L L + + ++D SSI + L L + G+ + G+ + L+L
Sbjct: 156 LTLRNLRKLRMKRTMVNDMWCSSIGLLKF-LVHLEVDGSRGVTDITGLFRLKTLEALSLD 214
Query: 109 KCSMVKLEMNFE----VPKLEVLNLSYTNVDDEALYMISKSCCGLLK-LSLENCNDFTKK 163
C + + F+ +P+L L+L TNV D+ L I G LK L + +C++ T
Sbjct: 215 NC--INITKGFDKICALPQLTSLSLCQTNVTDKDLRCIHPD--GKLKMLDISSCHEITDL 270
Query: 164 GVNHVVENCTQLRKISLDGCHKV 186
+ L K+SL GC V
Sbjct: 271 ---TAIGGVRSLEKLSLSGCWNV 290
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.323 0.136 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,696,836
Number of Sequences: 164201
Number of extensions: 850797
Number of successful extensions: 2918
Number of sequences better than 10.0: 46
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 2790
Number of HSP's gapped (non-prelim): 116
length of query: 230
length of database: 59,974,054
effective HSP length: 107
effective length of query: 123
effective length of database: 42,404,547
effective search space: 5215759281
effective search space used: 5215759281
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 64 (29.3 bits)
Medicago: description of AC148483.19