BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC148360.3 - phase: 0 
         (301 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

NPM_HUMAN (P06748) Nucleophosmin (NPM) (Nucleolar phosphoprotein...    45  2e-04
NPM_RAT (P13084) Nucleophosmin (NPM) (Nucleolar phosphoprotein B...    44  6e-04
HIR3_HUMAN (Q9BW71) HIRA-interacting protein 3                         42  0.001
HMG1_HUMAN (P09429) High mobility group protein 1 (HMG-1)              42  0.002
HMG1_BOVIN (P10103) High mobility group protein 1 (HMG-1)              42  0.002
NPM_MOUSE (Q61937) Nucleophosmin (NPM) (Nucleolar phosphoprotein...    42  0.002
HMG1_PIG (P12682) High mobility group protein 1 (HMG-1)                42  0.002
ATRX_PONPY (Q7YQM3) Transcriptional regulator ATRX (X-linked hel...    41  0.004
ATRX_PANTR (Q7YQM4) Transcriptional regulator ATRX (X-linked hel...    41  0.004
ATRX_HUMAN (P46100) Transcriptional regulator ATRX (X-linked hel...    41  0.004
SPL1_HUMAN (Q14515) SPARC-like protein 1 precursor (High endothe...    40  0.005
ATRX_CAEEL (Q9U7E0) Transcriptional regulator ATRX homolog (X-li...    40  0.007
WRN_HUMAN (Q14191) Werner syndrome helicase                            40  0.009
RIO1_YEAST (Q12196) RIO1 protein                                       40  0.009
HMG1_RAT (P63159) High mobility group protein 1 (HMG-1) (Amphote...    39  0.012
HMG1_MOUSE (P63158) High mobility group protein 1 (HMG-1)              39  0.012
HMG1_CRIGR (P07156) High mobility group protein 1 (HMG-1) (Fragm...    39  0.012
NUCL_XENLA (P20397) Nucleolin (Protein C23)                            39  0.016
NUCL_CHICK (P15771) Nucleolin (Protein C23)                            39  0.016
Z265_RAT (O35986) Zinc finger protein 265 (Zinc finger, splicing)      39  0.021

>NPM_HUMAN (P06748) Nucleophosmin (NPM) (Nucleolar phosphoprotein
           B23) (Numatrin) (Nucleolar protein NO38)
          Length = 294

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 59/224 (26%), Positives = 89/224 (39%), Gaps = 30/224 (13%)

Query: 80  CNLKKVEADWILRIDIVEKADRLELEEHDSEGQCNSECKTVERACQEVMGYSDTDVAEYL 139
           C LK  + D+  ++D  E   +L L           E   VE    E M Y  + +   L
Sbjct: 21  CELK-ADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEA---EAMNYEGSPIKVTL 76

Query: 140 YSSKPDID---SLTNYLCKD---LSKACNTKPPPVPKDRTPGEPFVAKSSKEAEMEKLLK 193
            + K  +    SL  +       L   C + P  +           A+S  E E +  L 
Sbjct: 77  ATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAESEDEEEEDVKLL 136

Query: 194 SMEGMPGAPGMKMYSRDDLMKKNFGAENEDDDEDE---DEEEDEADFPSKLGKILKSKEN 250
           S+ G   APG    S+    K    A+ +DDD+DE   DE++D+ DF           ++
Sbjct: 137 SISGKRSAPGGG--SKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDF-----------DD 183

Query: 251 EKGDWKQKIRKGIVDTSTTLKKHATKVSNHIQRWWKGKKTTSSK 294
           E+ + K  ++K I DT     K+A K SN   +  K   T  SK
Sbjct: 184 EEAEEKAPVKKSIRDTPA---KNAQK-SNQNGKDSKPSSTPRSK 223


>NPM_RAT (P13084) Nucleophosmin (NPM) (Nucleolar phosphoprotein B23)
           (Numatrin) (Nucleolar protein NO38)
          Length = 292

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 54/227 (23%), Positives = 87/227 (37%), Gaps = 30/227 (13%)

Query: 80  CNLKKVEADWILRIDIVEKADRLELEEHDSEGQCNSECKTVERACQEVMGYSDTDVAEYL 139
           C LK  + D+  ++D  E   +L L           E   VE    E M Y  + +   L
Sbjct: 21  CELK-ADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEA---EAMNYEGSPIKVTL 76

Query: 140 YSSKPDID---SLTNYLCKD---LSKACNTKPPPVPKDRTPGEPFVAKSSKEAEMEKLLK 193
            + K  +    SL  +       L   C + P  +           A+S  E E +  L 
Sbjct: 77  ATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAESEDEDEEDVKLL 136

Query: 194 SMEGMPGAPGMKMYSRDDLMKKNFGAENEDDDEDEDEEEDEADFPSKLGKILKSKENEKG 253
            M G   APG      + + +K    + +DD++DED+E+DE D            + E+ 
Sbjct: 137 GMSGKRSAPG----GGNKVPQKKVKLDEDDDEDDEDDEDDEDDDDDDF-------DEEET 185

Query: 254 DWKQKIRKGIVDTSTTLKKHATKVSNHIQRWWKGKKTTSSKKNSKSE 300
           + K  ++K + DT     K+A K + +      GK    S   SK +
Sbjct: 186 EEKVPVKKSVRDTPA---KNAQKSNQN------GKDLKPSTPRSKGQ 223


>HIR3_HUMAN (Q9BW71) HIRA-interacting protein 3
          Length = 556

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 30/106 (28%), Positives = 52/106 (48%), Gaps = 22/106 (20%)

Query: 163 TKPPPVPKDRTPGEPFVAKS-----SKEAEME---KLLKSMEGMPGAPGMKMYSRDDLMK 214
           T+  PV K + PG+  V++      S+E+E E   +  K +EG  G   +K   ++   +
Sbjct: 171 TRKKPVVKKQAPGKASVSRKQAREESEESEAEPVQRTAKKVEGNKGTKSLKESEQES--E 228

Query: 215 KNFGAENEDDDEDEDEEEDEADFPSKLGKILKSKENEKGDWKQKIR 260
           +   A+ ++  E+E EEE+            K ++ EKGDWK + R
Sbjct: 229 EEILAQKKEQREEEVEEEE------------KEEDEEKGDWKPRTR 262


>HMG1_HUMAN (P09429) High mobility group protein 1 (HMG-1)
          Length = 214

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 23/66 (34%), Positives = 34/66 (50%)

Query: 171 DRTPGEPFVAKSSKEAEMEKLLKSMEGMPGAPGMKMYSRDDLMKKNFGAENEDDDEDEDE 230
           D+ P E   AK  ++ E +      +G P A    +   +   KK    E+E+D+EDE+E
Sbjct: 139 DKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEE 198

Query: 231 EEDEAD 236
           EEDE D
Sbjct: 199 EEDEED 204


>HMG1_BOVIN (P10103) High mobility group protein 1 (HMG-1)
          Length = 214

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 23/66 (34%), Positives = 34/66 (50%)

Query: 171 DRTPGEPFVAKSSKEAEMEKLLKSMEGMPGAPGMKMYSRDDLMKKNFGAENEDDDEDEDE 230
           D+ P E   AK  ++ E +      +G P A    +   +   KK    E+E+D+EDE+E
Sbjct: 139 DKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEE 198

Query: 231 EEDEAD 236
           EEDE D
Sbjct: 199 EEDEED 204


>NPM_MOUSE (Q61937) Nucleophosmin (NPM) (Nucleolar phosphoprotein
           B23) (Numatrin) (Nucleolar protein NO38)
          Length = 292

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 54/227 (23%), Positives = 87/227 (37%), Gaps = 30/227 (13%)

Query: 80  CNLKKVEADWILRIDIVEKADRLELEEHDSEGQCNSECKTVERACQEVMGYSDTDVAEYL 139
           C LK  + D+  ++D  E   +L L           E   VE    E M Y  + +   L
Sbjct: 21  CELK-ADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEA---EAMNYEGSPIKVTL 76

Query: 140 YSSKPDID---SLTNYLCKD---LSKACNTKPPPVPKDRTPGEPFVAKSSKEAEMEKLLK 193
            + K  +    SL  +       L   C + P  +           A+S  E E +  L 
Sbjct: 77  ATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAESEDEDEEDVKLL 136

Query: 194 SMEGMPGAPGMKMYSRDDLMKKNFGAENEDDDEDEDEEEDEADFPSKLGKILKSKENEKG 253
            M G   APG    ++    K     ++EDDDED++++ED+ D            + E+ 
Sbjct: 137 GMSGKRSAPGGG--NKVPQKKVKLDEDDEDDDEDDEDDEDDDD---------DDFDEEET 185

Query: 254 DWKQKIRKGIVDTSTTLKKHATKVSNHIQRWWKGKKTTSSKKNSKSE 300
           + K  ++K + DT     K+A K + +      GK    S   SK +
Sbjct: 186 EEKVPVKKSVRDTPA---KNAQKSNQN------GKDLKPSTPRSKGQ 223


>HMG1_PIG (P12682) High mobility group protein 1 (HMG-1)
          Length = 214

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 23/66 (34%), Positives = 34/66 (50%)

Query: 171 DRTPGEPFVAKSSKEAEMEKLLKSMEGMPGAPGMKMYSRDDLMKKNFGAENEDDDEDEDE 230
           D+ P E   AK  ++ E +      +G P A    +   +   KK    E+E+D+EDE+E
Sbjct: 139 DKHPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEE 198

Query: 231 EEDEAD 236
           EEDE D
Sbjct: 199 EEDEED 204


>ATRX_PONPY (Q7YQM3) Transcriptional regulator ATRX (X-linked helicase
            II) (X-linked nuclear protein) (XNP)
          Length = 2492

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 45/199 (22%), Positives = 91/199 (45%), Gaps = 35/199 (17%)

Query: 109  SEGQCNSECKTVERACQEVMGYSDTDVAEYLYSSKPDIDSLTNYLCKDLSKACNTKPPPV 168
            S+G+   E KT  +  +EV G +   V+        D D   + + +++S++ + + P  
Sbjct: 1348 SDGESGEEKKTKPKEHKEVKGRNRRKVSS---EDSEDSDFQESGVSEEVSESEDEQRP-- 1402

Query: 169  PKDRTPGEPFVAKSSKEAEMEKLLKSMEGMPGAPGMKMYSRDDLMKKNFGAENEDDDEDE 228
               RT       +S+K+AE+E+  +S +       +K+        K+   E E++ E+E
Sbjct: 1403 ---RT-------RSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEE 1452

Query: 229  DEEEDEADFPSKLGKILKSKENEKGDWK------QKIRKGIVDTSTTLKKHATKVSNHIQ 282
            +EEE+E +         + +E+E  D K      +KIRK + D      K  T+  N ++
Sbjct: 1453 EEEEEEEE---------EEEEDENDDSKSPGKGRKKIRKILKD-----DKLRTETQNALK 1498

Query: 283  RWWKGKKTTSSKKNSKSEL 301
               + +K  + ++  + +L
Sbjct: 1499 EEEERRKRIAEREREREKL 1517


>ATRX_PANTR (Q7YQM4) Transcriptional regulator ATRX (X-linked helicase
            II) (X-linked nuclear protein) (XNP)
          Length = 2492

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 45/199 (22%), Positives = 91/199 (45%), Gaps = 35/199 (17%)

Query: 109  SEGQCNSECKTVERACQEVMGYSDTDVAEYLYSSKPDIDSLTNYLCKDLSKACNTKPPPV 168
            S+G+   E KT  +  +EV G +   V+        D D   + + +++S++ + + P  
Sbjct: 1348 SDGESGEEKKTKPKEHKEVKGRNRRKVSS---EDSEDSDFQESGVSEEVSESEDEQRP-- 1402

Query: 169  PKDRTPGEPFVAKSSKEAEMEKLLKSMEGMPGAPGMKMYSRDDLMKKNFGAENEDDDEDE 228
               RT       +S+K+AE+E+  +S +       +K+        K+   E E++ E+E
Sbjct: 1403 ---RT-------RSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEE 1452

Query: 229  DEEEDEADFPSKLGKILKSKENEKGDWK------QKIRKGIVDTSTTLKKHATKVSNHIQ 282
            +EEE+E +         + +E+E  D K      +KIRK + D      K  T+  N ++
Sbjct: 1453 EEEEEEEE---------EEEEDENDDSKSPGKGRKKIRKILKD-----DKLRTETQNALK 1498

Query: 283  RWWKGKKTTSSKKNSKSEL 301
               + +K  + ++  + +L
Sbjct: 1499 EEEERRKRIAEREREREKL 1517


>ATRX_HUMAN (P46100) Transcriptional regulator ATRX (X-linked helicase
            II) (X-linked nuclear protein) (XNP) (Znf-HX)
          Length = 2492

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 45/199 (22%), Positives = 91/199 (45%), Gaps = 35/199 (17%)

Query: 109  SEGQCNSECKTVERACQEVMGYSDTDVAEYLYSSKPDIDSLTNYLCKDLSKACNTKPPPV 168
            S+G+   E KT  +  +EV G +   V+        D D   + + +++S++ + + P  
Sbjct: 1348 SDGESGEEKKTKPKEHKEVKGRNRRKVSS---EDSEDSDFQESGVSEEVSESEDEQRP-- 1402

Query: 169  PKDRTPGEPFVAKSSKEAEMEKLLKSMEGMPGAPGMKMYSRDDLMKKNFGAENEDDDEDE 228
               RT       +S+K+AE+E+  +S +       +K+        K+   E E++ E+E
Sbjct: 1403 ---RT-------RSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEE 1452

Query: 229  DEEEDEADFPSKLGKILKSKENEKGDWK------QKIRKGIVDTSTTLKKHATKVSNHIQ 282
            +EEE+E +         + +E+E  D K      +KIRK + D      K  T+  N ++
Sbjct: 1453 EEEEEEEE---------EEEEDENDDSKSPGKGRKKIRKILKD-----DKLRTETQNALK 1498

Query: 283  RWWKGKKTTSSKKNSKSEL 301
               + +K  + ++  + +L
Sbjct: 1499 EEEERRKRIAEREREREKL 1517


>SPL1_HUMAN (Q14515) SPARC-like protein 1 precursor (High
           endothelial venule protein) (Hevin) (MAST 9)
          Length = 664

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 34/197 (17%), Positives = 87/197 (43%), Gaps = 11/197 (5%)

Query: 86  EADWILRIDIVEKADRLELEEHDSEGQCNSECKTVERACQEVMGYSDTDVAEYLYSSKPD 145
           + D  + ++       L+++E  SE Q     +  +     V  ++D++  E +   + +
Sbjct: 104 DGDLSVNLEYAPSEGTLDIKEDMSEPQEKKLSENTDFLAPGVSSFTDSNQQESITKREEN 163

Query: 146 IDSLTNYLCKDLSKACNTKPPPVPKDRTPGEPFVAKSSKEAEMEKLLKSMEGMPGAPGMK 205
            +   NY    L+++         +     +P ++   +E E E       G  G     
Sbjct: 164 QEQPRNYSHHQLNRSSKHSQGLRDQGNQEQDPNISNGEEEEEKEP------GEVGTHNDN 217

Query: 206 MYSRDDLMKKNFGAENEDDDEDEDEEEDEADFPSKLGKILKSKENEKGDWKQKIRKGIVD 265
              + +L +++  ++ E+D+   D+  +E+D P+++ K ++  E ++G+ +Q+       
Sbjct: 218 QERKTELPREHANSKQEEDNTQSDDILEESDQPTQVSK-MQEDEFDQGNQEQEDN----S 272

Query: 266 TSTTLKKHATKVSNHIQ 282
            +   +++A+ V+ HIQ
Sbjct: 273 NAEMEEENASNVNKHIQ 289


>ATRX_CAEEL (Q9U7E0) Transcriptional regulator ATRX homolog
           (X-linked nuclear protein-1)
          Length = 1359

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 28/122 (22%), Positives = 54/122 (43%), Gaps = 1/122 (0%)

Query: 180 AKSSKEAEMEKLLKSMEGMPGAPGMKMYSRDDLMKKNFGAENEDDDEDEDEEEDEADFPS 239
           AKS  E++     +  +       +    ++   KK   + +ED+D DE+ E+       
Sbjct: 86  AKSESESDESDEEEDRKKSKSKKKVDQKKKEKSKKKRTTSSSEDEDSDEEREQKSKKKSK 145

Query: 240 KLGKILKSKENEKGDWKQKIRKGIVDTSTTLKKHATKVSNHIQRWWKGKKTTSS-KKNSK 298
           K  K   S+ +E+ + ++K++K   +   ++KK A       +     KK+    KK +K
Sbjct: 146 KTKKQTSSESSEESEEERKVKKSKKNKEKSVKKRAETSEESDEDEKPSKKSKKGLKKKAK 205

Query: 299 SE 300
           SE
Sbjct: 206 SE 207



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 37/137 (27%), Positives = 59/137 (43%), Gaps = 24/137 (17%)

Query: 164 KPPPVPKDRTPGEPFVAKSSKEAEMEKLLKSMEGMPGAPGMKMYSRDDLMKKNFGAENED 223
           KPPP    + P +   A SS+E + ++     E  P     K   R         A++E 
Sbjct: 48  KPPP---KKRPAKKRKASSSEEDDDDE-----EESPRKSSKKSRKR---------AKSES 90

Query: 224 DDEDEDEEEDEADFPSKLGKILKSKENEKGDWKQKIRKGIVDTSTTLKKHATKVSNHIQR 283
           + ++ DEEED     SK  K +  K+ EK   K+       + S   ++  +K  +    
Sbjct: 91  ESDESDEEEDRKKSKSK--KKVDQKKKEKSKKKRTTSSSEDEDSDEEREQKSKKKSK--- 145

Query: 284 WWKGKKTTSSKKNSKSE 300
             K KK TSS+ + +SE
Sbjct: 146 --KTKKQTSSESSEESE 160



 Score = 34.3 bits (77), Expect = 0.39
 Identities = 34/136 (25%), Positives = 57/136 (41%), Gaps = 18/136 (13%)

Query: 181 KSSKEAEMEKLLKSMEGMPGAPGMKMYSRDDLMKKNFGAENEDDDEDEDEEEDEAD---- 236
           K SK+   + + K  E    AP  K   +    K +    +E +  DE+EEE E+     
Sbjct: 219 KKSKKKSKKVVKKESESEDEAPEKKKTEKRKRSKTSSEESSESEKSDEEEEEKESSPKPK 278

Query: 237 --FPSKLGKILKSKENEKGDWK---QKIRKGIV--------DTSTTLKKHATKVSNHIQR 283
              P  + K+   +E+E+ D +   QK ++G V        +     +  A+ V   + +
Sbjct: 279 KKKPLAVKKLSSDEESEESDVEVLPQKKKRGAVTLISDSEDEKDQKSESEASDVEEKVSK 338

Query: 284 WWKGKKTTSSKKNSKS 299
             K KK  SS+  S S
Sbjct: 339 -KKAKKQESSESGSDS 353



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 48/207 (23%), Positives = 80/207 (38%), Gaps = 19/207 (9%)

Query: 103 ELEEHDSEGQCNSECKTVERACQEVMG-YSDTDVAEYLYSSKPDIDSLTNYLCKDLSKAC 161
           E ++ + E    S  K+ +RA  E     SD +       SK  +D       K   K+ 
Sbjct: 66  EDDDDEEESPRKSSKKSRKRAKSESESDESDEEEDRKKSKSKKKVDQ------KKKEKSK 119

Query: 162 NTKPPPVPKDRTPGEPFVAKSSKEAEMEKLLKSMEGMPGAPGMKMYSRDDLMKKNFGAEN 221
             +     +D    E    KS K+++  K   S E    +   +   +    K+    + 
Sbjct: 120 KKRTTSSSEDEDSDEEREQKSKKKSKKTKKQTSSESSEESEEERKVKKSKKNKEKSVKKR 179

Query: 222 EDDDEDEDEEEDEADFPSKLGKI-LKSKENEKGDWKQKIRKGIVDTSTTLKKHATKVSNH 280
            +  E+ DE+E     PSK  K  LK K   + + + +  K +  +    KK   K S  
Sbjct: 180 AETSEESDEDEK----PSKKSKKGLKKKAKSESESESEDEKEVKKSKKKSKKVVKKESES 235

Query: 281 IQRWWKGKKT-------TSSKKNSKSE 300
                + KKT       TSS+++S+SE
Sbjct: 236 EDEAPEKKKTEKRKRSKTSSEESSESE 262


>WRN_HUMAN (Q14191) Werner syndrome helicase
          Length = 1432

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 36/161 (22%), Positives = 75/161 (46%), Gaps = 24/161 (14%)

Query: 83  KKVEADWILRIDIVEKADRLELEEHDSEGQCNSECKTVERACQEVMGYSDTDVAEYLYSS 142
           + +E   ++ +DI E    L++ E  S+ +  S+     ++ + +    + +   Y+  S
Sbjct: 385 ENMERACLMSLDITEH--ELQILEQQSQEEYLSDI--AYKSTEHLSPNDNENDTSYVIES 440

Query: 143 KPDIDSLTNYLCKDLSKACNTKPPPVPKDRTPGEPFVAKSSKEAEMEKLLKSMEGMPGAP 202
             D++     + K LS          P D      +V +S ++ EME +LKS+E +    
Sbjct: 441 DEDLEM---EMLKHLS----------PNDNENDTSYVIESDEDLEME-MLKSLENLNSGT 486

Query: 203 GMKMYSRDDLMKKNFGAENEDDDEDED------EEEDEADF 237
               +S+   M++N G   ++++ED++      EE+D+ DF
Sbjct: 487 VEPTHSKCLKMERNLGLPTKEEEEDDENEANEGEEDDDKDF 527


>RIO1_YEAST (Q12196) RIO1 protein
          Length = 484

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 29/86 (33%), Positives = 45/86 (51%), Gaps = 11/86 (12%)

Query: 210 DDLMKKNFGAENEDDDEDEDEEEDEADFPSKLGKILKSKENEKGDWKQKIRKGIVDTSTT 269
           DD    + G+E +D++E E  ++DE        K+LK K++E  D K+  ++   D    
Sbjct: 410 DDEEDGSSGSEEDDEEEGEYYDDDEP-------KVLKGKKHEDKDLKKLRKQEAKDAKR- 461

Query: 270 LKKHATKVSNHIQRWWKGKKTTSSKK 295
            +K  TKV  HI++  K  K T SKK
Sbjct: 462 -EKRKTKVKKHIKK--KLVKKTKSKK 484


>HMG1_RAT (P63159) High mobility group protein 1 (HMG-1)
           (Amphoterin) (Heparin-binding protein p30)
          Length = 214

 Score = 39.3 bits (90), Expect = 0.012
 Identities = 21/66 (31%), Positives = 34/66 (50%)

Query: 171 DRTPGEPFVAKSSKEAEMEKLLKSMEGMPGAPGMKMYSRDDLMKKNFGAENEDDDEDEDE 230
           D+ P E   AK  ++ E +      +G P A    +   +   KK    ++E+D+EDE+E
Sbjct: 139 DKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEE 198

Query: 231 EEDEAD 236
           EE+E D
Sbjct: 199 EEEEED 204


>HMG1_MOUSE (P63158) High mobility group protein 1 (HMG-1)
          Length = 214

 Score = 39.3 bits (90), Expect = 0.012
 Identities = 21/66 (31%), Positives = 34/66 (50%)

Query: 171 DRTPGEPFVAKSSKEAEMEKLLKSMEGMPGAPGMKMYSRDDLMKKNFGAENEDDDEDEDE 230
           D+ P E   AK  ++ E +      +G P A    +   +   KK    ++E+D+EDE+E
Sbjct: 139 DKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEE 198

Query: 231 EEDEAD 236
           EE+E D
Sbjct: 199 EEEEED 204


>HMG1_CRIGR (P07156) High mobility group protein 1 (HMG-1)
           (Fragment)
          Length = 180

 Score = 39.3 bits (90), Expect = 0.012
 Identities = 21/66 (31%), Positives = 34/66 (50%)

Query: 171 DRTPGEPFVAKSSKEAEMEKLLKSMEGMPGAPGMKMYSRDDLMKKNFGAENEDDDEDEDE 230
           D+ P E   AK  ++ E +      +G P A    +   +   KK    ++E+D+EDE+E
Sbjct: 105 DKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEE 164

Query: 231 EEDEAD 236
           EE+E D
Sbjct: 165 EEEEED 170


>NUCL_XENLA (P20397) Nucleolin (Protein C23)
          Length = 650

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 6/85 (7%)

Query: 168 VPKDRTPGEPFVAKSSKEAEMEKLLKSMEGMPGAPGMKMYSRDDLMKKNFGAENEDDDED 227
           V K  TP +    K  +  E +      E M  AP +K        K    AE +D++ED
Sbjct: 137 VAKKPTPAKKPAGKKQESEEEDDEESEDEPMEVAPALKG------KKTAQAAEEDDEEED 190

Query: 228 EDEEEDEADFPSKLGKILKSKENEK 252
           +D+EED+ D   + G   + KE  K
Sbjct: 191 DDDEEDDDDEEEQQGSAKRKKEMPK 215



 Score = 34.7 bits (78), Expect = 0.30
 Identities = 24/96 (25%), Positives = 41/96 (42%), Gaps = 4/96 (4%)

Query: 159 KACNTKPPPVPKDRTPGEPFVAKSSKEAEMEKLLKSMEGMPGAPGMKMYSRDDLMKKNFG 218
           KA   KP P  K     +    +  +E+E E     ME  P   G K     +   +   
Sbjct: 135 KAVAKKPTPAKKPAGKKQESEEEDDEESEDEP----MEVAPALKGKKTAQAAEEDDEEED 190

Query: 219 AENEDDDEDEDEEEDEADFPSKLGKILKSKENEKGD 254
            ++E+DD+DE+E++  A    ++ K +   +  K D
Sbjct: 191 DDDEEDDDDEEEQQGSAKRKKEMPKTIPEAKKTKTD 226



 Score = 31.2 bits (69), Expect = 3.3
 Identities = 27/113 (23%), Positives = 44/113 (38%), Gaps = 11/113 (9%)

Query: 168 VPKDRTPGEPFVAKSSKEAEMEKLLKSMEGMPGAPGMKMYSRDDLMKKNFGAENEDDDED 227
           VP  +TP +       K A   K        PG  G          KK    E EDD ++
Sbjct: 45  VPVKKTPAK-------KTATPAKATPGKAATPGKKGATPAKNGKQAKKQESEEEEDDSDE 97

Query: 228 EDEEE----DEADFPSKLGKILKSKENEKGDWKQKIRKGIVDTSTTLKKHATK 276
           E E++    ++      + K  +S+E++  + + +  K +    T  KK A K
Sbjct: 98  EAEDQKPIKNKPVAKKAVAKKEESEEDDDDEDESEEEKAVAKKPTPAKKPAGK 150



 Score = 30.4 bits (67), Expect = 5.6
 Identities = 26/77 (33%), Positives = 41/77 (52%), Gaps = 17/77 (22%)

Query: 182 SSKEAEMEKLLKSMEGMPGAPGMKMYSRDDLMKKNFGAENEDDDEDEDEEEDE---ADFP 238
           S +EAE +K +K+          K  ++  + KK    E+E+DD+DEDE E+E   A  P
Sbjct: 95  SDEEAEDQKPIKN----------KPVAKKAVAKKE---ESEEDDDDEDESEEEKAVAKKP 141

Query: 239 SKLGKIL-KSKENEKGD 254
           +   K   K +E+E+ D
Sbjct: 142 TPAKKPAGKKQESEEED 158


>NUCL_CHICK (P15771) Nucleolin (Protein C23)
          Length = 694

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 22/73 (30%), Positives = 39/73 (53%)

Query: 167 PVPKDRTPGEPFVAKSSKEAEMEKLLKSMEGMPGAPGMKMYSRDDLMKKNFGAENEDDDE 226
           P  K  TP +  VA  +K+A      K+     GA   K   +++  +++   E++++DE
Sbjct: 71  PAKKAVTPAKKAVATPAKKAVAPSPKKAAVVGKGAKNGKNAKKEESEEEDEDDEDDEEDE 130

Query: 227 DEDEEEDEADFPS 239
           DE+EE DE + P+
Sbjct: 131 DEEEESDEEEEPA 143



 Score = 37.7 bits (86), Expect = 0.035
 Identities = 58/239 (24%), Positives = 89/239 (36%), Gaps = 29/239 (12%)

Query: 24  AKKPVGIARKEDVPYIKCQVCEILAKQLYQQVQSKKAEISPKKISEYQIIEIAENVCNLK 83
           AKK    A+K   P  K       AK+       K    SPKK +   + + A+N  N K
Sbjct: 58  AKKAATPAKKAATPAKKAVTP---AKKAVATPAKKAVAPSPKKAAV--VGKGAKNGKNAK 112

Query: 84  KVEADWILRIDIVEKADRLELEEHDSEGQCNSECKTVERACQEVMGYSDTDVAEYLYSSK 143
           K E++     D  ++ D  E EE D E +     K   +     +      V      S+
Sbjct: 113 KEESEEEDEDDEDDEEDEDEEEESDEEEEPAVPVKPAAKKSAAAVPAKKPAVVPAKQESE 172

Query: 144 P----DIDSLTNYLCKDLSKACNTKPPPVPKDRTPGEPFVAKSSKEAEMEKLLKSMEGMP 199
                D +       +   +A +T P PV K  TP +   AK+  E+E E+         
Sbjct: 173 EEEEEDDEEEDEEDDESEDEAMDTTPAPVKKP-TPAKATPAKAKAESEDEE--------- 222

Query: 200 GAPGMKMYSRDDLMKKNFGAENEDDDEDEDEEEDEADFPSKLGKILKSKENEKGDWKQK 258
                     D+  +     + +D++EDE+E EDE       GK  K   N+     +K
Sbjct: 223 ----------DEEDEDEDEEDEDDEEEDEEESEDEKPVKEAPGKRKKEMANKSAPEAKK 271


>Z265_RAT (O35986) Zinc finger protein 265 (Zinc finger, splicing)
          Length = 332

 Score = 38.5 bits (88), Expect = 0.021
 Identities = 53/248 (21%), Positives = 95/248 (37%), Gaps = 42/248 (16%)

Query: 81  NLKKVEADWILRIDIVEKADRLELEEHDSEGQCNSECKTVERACQEVMGYSDTDVAEYLY 140
           N +  + DWI      +K   +      S  +C  E KT E    +  G   T++ + L 
Sbjct: 5   NFRVSDGDWICPD---KKCGNVNFARRTSCNRCGRE-KTTEAKMMKAGG---TEIGKTLA 57

Query: 141 SSKPDIDSLTNYLCKDLSKA----------CNTKPPPVPKDRT---------PGEPFVAK 181
                + S  ++ CK  S            CNT      ++RT             ++ +
Sbjct: 58  EKSRGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIER 117

Query: 182 SSKEAEMEKL---LKSMEGMPGAPGMKMYSRDDLMKKNFGAENEDDDED-------EDEE 231
              + E ++     K   G    P   +   +D   K    E ED+DED       EDE+
Sbjct: 118 EESDGEYDEFGRKKKKYRGKAVGPASILKEVED---KESEGEEEDEDEDLSKYKLDEDED 174

Query: 232 EDEADFPSKLGKILKSKENEKGDWKQKIRKGIVDTSTTLKKHATKVSNHIQRWWKGKKTT 291
           ED+AD  SK    L + E E  + K+  R+    + ++  + +++ S+      + +  +
Sbjct: 175 EDDADL-SKYN--LDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRS 231

Query: 292 SSKKNSKS 299
            S  +S+S
Sbjct: 232 RSSSSSQS 239


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.311    0.129    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,065,513
Number of Sequences: 164201
Number of extensions: 1652156
Number of successful extensions: 16528
Number of sequences better than 10.0: 424
Number of HSP's better than 10.0 without gapping: 199
Number of HSP's successfully gapped in prelim test: 235
Number of HSP's that attempted gapping in prelim test: 12340
Number of HSP's gapped (non-prelim): 1600
length of query: 301
length of database: 59,974,054
effective HSP length: 110
effective length of query: 191
effective length of database: 41,911,944
effective search space: 8005181304
effective search space used: 8005181304
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)