BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC147404.4 - phase: 0 
         (583 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

PT2B_ARATH (P46032) Peptide transporter PTR2-B (Histidine transp...   459  e-128
CHL1_ARATH (Q05085) Nitrate/chlorate transporter                      355  1e-97
PET1_HUMAN (P46059) Oligopeptide transporter, small intestine is...   125  3e-28
PET1_RAT (P51574) Oligopeptide transporter, small intestine isof...   120  8e-27
PET1_RABIT (P36836) Oligopeptide transporter, small intestine is...   117  1e-25
PET2_RABIT (P46029) Oligopeptide transporter, kidney isoform (Pe...   114  9e-25
PET2_RAT (Q63424) Oligopeptide transporter, kidney isoform (Pept...   112  3e-24
PET2_HUMAN (Q16348) Oligopeptide transporter, kidney isoform (Pe...   109  2e-23
OPT1_DROME (P91679) Oligopeptide transporter 1 (YIN protein)          105  2e-22
OPT1_CAEEL (Q17758) Oligopeptide transporter 1 (Di-/tri-peptide ...   102  2e-21
PTR2_SCHPO (Q9P380) Probable peptide transporter Ptr2 (Peptide p...    96  3e-19
OPT3_CAEEL (O01840) Putative oligopeptide transporter opt-3            92  5e-18
OPT2_CAEEL (Q21219) Oligopeptide transporter 2 (Di-/tri-peptide ...    91  6e-18
PTR2_YEAST (P32901) Peptide transporter PTR2 (Peptide permease P...    87  9e-17
YBGH_ECOLI (P75742) Hypothetical transporter ybgH                      69  3e-11
YJDL_ECOLI (P39276) Hypothetical transporter yjdL                      68  6e-11
YCLF_BACSU (P94408) Hypothetical transporter yclF                      64  8e-10
PT2A_ARATH (P46031) Peptide transporter PTR2-A                         64  1e-09
DTPT_LACLA (P36574) Di-/tripeptide transporter                         63  2e-09
DTPT_LACHE (O07380) Di-/tripeptide transporter                         60  2e-08

>PT2B_ARATH (P46032) Peptide transporter PTR2-B (Histidine
           transporting protein)
          Length = 585

 Score =  459 bits (1180), Expect = e-128
 Identities = 238/566 (42%), Positives = 353/566 (62%), Gaps = 11/566 (1%)

Query: 1   GKFKEETEELTLDGSVDWHGRPSIRATSGRWFAGTIILLNQGLATLAFFGVGVNLVLFLT 60
           G   +E +    DGSVD++G P ++  +G W A   IL N+    LA++G+  NL+ +LT
Sbjct: 15  GLILQEVKLYAEDGSVDFNGNPPLKEKTGNWKACPFILGNECCERLAYYGIAGNLITYLT 74

Query: 61  RVLGQDNAAAANNVSKWTGTVYIFSLVGAFLSDSYWGRYKTCAIFQGIFVTGLVSLSVTT 120
             L Q N +AA NV+ W GT Y+  L+GA L+D+YWGRY T A F GI+  G+ +L+++ 
Sbjct: 75  TKLHQGNVSAATNVTTWQGTCYLTPLIGAVLADAYWGRYWTIACFSGIYFIGMSALTLSA 134

Query: 121 YLALLRPKGCGNGKLECGEHSSLEMGMFYLSIYLIALGNGGYQPNIATFGADQFDEDHSK 180
            +  L+P  C      C   +  +  MF+  +YLIALG GG +P +++FGADQFD+  S+
Sbjct: 135 SVPALKPAECIGDF--CPSATPAQYAMFFGGLYLIALGTGGIKPCVSSFGADQFDDTDSR 192

Query: 181 ESYSKVAFFSYFYLALNLGSLFSNTILGYFEDEGLWALGFWASAGSAFLALVLFLVGTPK 240
           E   K +FF++FY ++N+G+L S+++L + ++   W LGF        LA+  F  GTP 
Sbjct: 193 ERVRKASFFNWFYFSINIGALVSSSLLVWIQENRGWGLGFGIPTVFMGLAIASFFFGTPL 252

Query: 241 YRHFKPCGNPLSRFCQVFFAASRKLGVQMTSNGDDLYVIDEKESSNNSNRKILHTHGFKF 300
           YR  KP G+P++R  QV  A+ RK  V++  +   LY   +K S+   +RKI HT   ++
Sbjct: 253 YRFQKPGGSPITRISQVVVASFRKSSVKVPEDATLLYETQDKNSAIAGSRKIEHTDDCQY 312

Query: 301 LDRAAYITSRDLEVQKGGQHNPWYLCPITQVEEVKCILRLLPIWLCTIIYSVVFTQMASL 360
           LD+AA I+    E + G   N W LC +TQVEE+K ++R+ PIW   II+S V+ QM+++
Sbjct: 313 LDKAAVISEE--ESKSGDYSNSWRLCTVTQVEELKILIRMFPIWASGIIFSAVYAQMSTM 370

Query: 361 FVEQGAAMKTTISSFKIPPASMSSFDILSVAIFIFFYRRVLDPLVGKLKKSSSKGLTELQ 420
           FV+QG AM   I SF++PPA++ +FD  SV I++  Y R + PL  K      KG TE+Q
Sbjct: 371 FVQQGRAMNCKIGSFQLPPAALGTFDTASVIIWVPLYDRFIVPLARKF-TGVDKGFTEIQ 429

Query: 421 RMGIGLVIAIIAMVTAGIVECYRLKYA------KQGDTSSLSIFWQIPQYALIGASEVFM 474
           RMGIGL ++++ M  A IVE  RL  A      + G    +S+ WQIPQY ++GA+EVF 
Sbjct: 430 RMGIGLFVSVLCMAAAAIVEIIRLHMANDLGLVESGAPVPISVLWQIPQYFILGAAEVFY 489

Query: 475 YVGQLEFFNAQTPDGLKSFGSALCMTSISLGNYVSSLIVSIVMKISTEDHMPGWIPGNLN 534
           ++GQLEFF  Q+PD ++S  SAL + + +LGNY+SSLI+++V   +T +   GWI  NLN
Sbjct: 490 FIGQLEFFYDQSPDAMRSLCSALALLTNALGNYLSSLILTLVTYFTTRNGQEGWISDNLN 549

Query: 535 RGHLDRFFFLLAVLTSLDLIAYIACA 560
            GHLD FF+LLA L+ +++  Y   A
Sbjct: 550 SGHLDYFFWLLAGLSLVNMAVYFFSA 575


>CHL1_ARATH (Q05085) Nitrate/chlorate transporter
          Length = 590

 Score =  355 bits (912), Expect = 1e-97
 Identities = 207/567 (36%), Positives = 328/567 (57%), Gaps = 16/567 (2%)

Query: 6   ETEELTLDGSVDWHGRPSIRATSGRWFAGTIILLNQGLATLAFFGVGVNLVLFLTRVLGQ 65
           +++++ LD + D+ GRP+ R+ +G W +  +IL  + +  L   G+GVNLV +LT  +  
Sbjct: 7   KSDDILLD-AWDFQGRPADRSKTGGWASAAMILCIEAVERLTTLGIGVNLVTYLTGTMHL 65

Query: 66  DNAAAANNVSKWTGTVYIFSLVGAFLSDSYWGRYKTCAIFQGIFVTGLVSLSVTTYLALL 125
            NA AAN V+ + GT ++  L+G F++D++ GRY T AIF  I  TG+  L+++T +  L
Sbjct: 66  GNATAANTVTNFLGTSFMLCLLGGFIADTFLGRYLTIAIFAAIQATGVSILTLSTIIPGL 125

Query: 126 RPKGCG-NGKLECGEHSSLEMGMFYLSIYLIALGNGGYQPNIATFGADQFDEDHSKESYS 184
           RP  C       C + S +++ + YL++YL ALG GG + +++ FG+DQFDE   KE   
Sbjct: 126 RPPRCNPTTSSHCEQASGIQLTVLYLALYLTALGTGGVKASVSGFGSDQFDETEPKERSK 185

Query: 185 KVAFFSYFYLALNLGSLFSNTILGYFEDEGLWALGFWASAGSAFLALVLFLVGTPKYRHF 244
              FF+ F+  +N+GSL + T+L Y +D+     G+   A +  LAL +FL GT +YR  
Sbjct: 186 MTYFFNRFFFCINVGSLLAVTVLVYVQDDVGRKWGYGICAFAIVLALSVFLAGTNRYRFK 245

Query: 245 KPCGNPLSRFCQVFFAASRKLGVQMTSNGDDLYVIDE---KESSNNSNRKILHTHGFKFL 301
           K  G+P+++   V  AA R   +++ ++   LY +D+    E S    +K+ HT  F+ L
Sbjct: 246 KLIGSPMTQVAAVIVAAWRNRKLELPADPSYLYDVDDIIAAEGSMKGKQKLPHTEQFRSL 305

Query: 302 DRAAYITSRDLEV-QKGGQHNPWYLCPITQVEEVKCILRLLPIWLCTIIYSVVFTQMASL 360
           D+AA    RD E        N W L  +T VEEVK I+R+LPIW   I++  V  Q+ +L
Sbjct: 306 DKAAI---RDQEAGVTSNVFNKWTLSTLTDVEEVKQIVRMLPIWATCILFWTVHAQLTTL 362

Query: 361 FVEQGAAMKTTISSFKIPPASMSSFDILSVAIFIFFYRRVLDPLVGKLKKSSSKGLTELQ 420
            V Q   +  +I SF+IPPASM+ F +  + +    Y RV   L  KL  +   GL  LQ
Sbjct: 363 SVAQSETLDRSIGSFEIPPASMAVFYVGGLLLTTAVYDRVAIRLCKKL-FNYPHGLRPLQ 421

Query: 421 RMGIGLVIAIIAMVTAGIVECYRLKYAKQG----DTSSLSIFWQIPQYALIGASEVFMYV 476
           R+G+GL    +AM  A +VE  RL+ A        T  L  +  IPQY ++G  E  +Y 
Sbjct: 422 RIGLGLFFGSMAMAVAALVELKRLRTAHAHGPTVKTLPLGFYLLIPQYLIVGIGEALIYT 481

Query: 477 GQLEFFNAQTPDGLKSFGSALCMTSISLGNYVSSLIVSIVMKISTEDHMPGWIPGNLNRG 536
           GQL+FF  + P G+K   + L +++++LG + SS++V+IV K + + H   WI  +LN+G
Sbjct: 482 GQLDFFLRECPKGMKGMSTGLLLSTLALGFFFSSVLVTIVEKFTGKAH--PWIADDLNKG 539

Query: 537 HLDRFFFLLAVLTSLDLIAYIACAKWF 563
            L  F++L+AVL +L+ + ++  +KW+
Sbjct: 540 RLYNFYWLVAVLVALNFLIFLVFSKWY 566


>PET1_HUMAN (P46059) Oligopeptide transporter, small intestine
           isoform (Peptide transporter 1) (Intestinal H(+)/peptide
           cotransporter) (Solute carrier family 15, member 1)
          Length = 708

 Score =  125 bits (314), Expect = 3e-28
 Identities = 95/412 (23%), Positives = 180/412 (43%), Gaps = 59/412 (14%)

Query: 37  ILLNQGLATLAFFGVGVNLVLFLTRVLGQDNAAAANNVSKWTGTVYIFSLVGAFLSDSYW 96
           I++N+     +++G+   L+L+ T  +  D+  +      +    Y+  ++GA ++DS+ 
Sbjct: 19  IVVNEFCERFSYYGMRAILILYFTNFISWDDNLSTAIYHTFVALCYLTPILGALIADSWL 78

Query: 97  GRYKTCAIFQGIFVTGLVSLSVTTYLALLRPKGCGNGKLECGEHSSLEMGMFYLSIYLIA 156
           G++KT      ++  G    SV++   L      G       +   + + +  + + LIA
Sbjct: 79  GKFKTIVSLSIVYTIGQAVTSVSSINDLTDHNHDGT-----PDSLPVHVVLSLIGLALIA 133

Query: 157 LGNGGYQPNIATFGADQFDEDHSKESYSKVAFFSYFYLALNLGSLFSNTI--------LG 208
           LG GG +P ++ FG DQF+E   K+   +  FFS FYLA+N GSL S  I         G
Sbjct: 134 LGTGGIKPCVSAFGGDQFEEGQEKQ---RNRFFSIFYLAINAGSLLSTIITPMLRVQQCG 190

Query: 209 YFEDEGLWALGFWASAGSAFLALVLFLVGTPKYRHFKPCGNPLSRFCQVFFAASRKLGVQ 268
               +  + L F   A    +AL++F++G+  Y+ FKP GN + +  +    A +     
Sbjct: 191 IHSKQACYPLAFGVPAALMAVALIVFVLGSGMYKKFKPQGNIMGKVAKCIGFAIKN---- 246

Query: 269 MTSNGDDLYVIDEKESSNNSNRKILHTHGFKFLDRAAYITSRDLEVQKGGQHNPWYLCPI 328
                                         +F  R+     R+  +    +     L   
Sbjct: 247 ------------------------------RFRHRSKAFPKREHWLDWAKEKYDERL--- 273

Query: 329 TQVEEVKCILRLLPIWLCTIIYSVVFTQMASLFVEQGAAMKTTISSFKIPPASMSSFDIL 388
             + ++K + R++ +++   ++  +F Q  S +  Q   M   I + +I P  M + + +
Sbjct: 274 --ISQIKMVTRVMFLYIPLPMFWALFDQQGSRWTLQATTMSGKIGALEIQPDQMQTVNAI 331

Query: 389 SVAIFIFFYRRVLDPLVGKLKKSSSKGLTELQRMGIGLVIAIIAMVTAGIVE 440
            + I +  +  VL PL+ K         T L++M +G+V+A +A V A IV+
Sbjct: 332 LIVIMVPIFDAVLYPLIAK----CGFNFTSLKKMAVGMVLASMAFVVAAIVQ 379



 Score = 40.4 bits (93), Expect = 0.013
 Identities = 21/72 (29%), Positives = 39/72 (54%)

Query: 441 CYRLKYAKQGDTSSLSIFWQIPQYALIGASEVFMYVGQLEFFNAQTPDGLKSFGSALCMT 500
           C  +K  +    +++++  QIPQY L+   EV   V  LEF  +Q P  +KS   A  + 
Sbjct: 565 CPEVKVFEDISANTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLL 624

Query: 501 SISLGNYVSSLI 512
           ++++GN +  ++
Sbjct: 625 TVAVGNIIVLIV 636


>PET1_RAT (P51574) Oligopeptide transporter, small intestine isoform
           (Peptide transporter 1) (Intestinal H(+)/peptide
           cotransporter) (Proton-coupled dipeptide cotransporter)
          Length = 710

 Score =  120 bits (302), Expect = 8e-27
 Identities = 94/412 (22%), Positives = 180/412 (42%), Gaps = 59/412 (14%)

Query: 37  ILLNQGLATLAFFGVGVNLVLFLTRVLGQDNAAAANNVSKWTGTVYIFSLVGAFLSDSYW 96
           I++N+     +++G+   LVL+    LG D+  +      +    Y+  ++GA ++DS+ 
Sbjct: 19  IVVNEFCERFSYYGMRALLVLYFRNFLGWDDDLSTAIYHTFVALCYLTPILGALIADSWL 78

Query: 97  GRYKTCAIFQGIFVTGLVSLSVTTYLALLRPKGCGNGKLECGEHSSLEMGMFYLSIYLIA 156
           G++KT      ++  G   +SV++   L      G+       +  L + +  + + LIA
Sbjct: 79  GKFKTIVSLSIVYTIGQAVISVSSINDLTDHDHDGS-----PNNLPLHVALSMIGLALIA 133

Query: 157 LGNGGYQPNIATFGADQFDEDHSKESYSKVAFFSYFYLALNLGSLFSNTI--------LG 208
           LG GG +P ++ FG DQF+E   K+   +  FFS FYLA+N GSL S  I         G
Sbjct: 134 LGTGGIKPCVSAFGGDQFEEGQEKQ---RNRFFSIFYLAINAGSLLSTIITPILRVQQCG 190

Query: 209 YFEDEGLWALGFWASAGSAFLALVLFLVGTPKYRHFKPCGNPLSRFCQVFFAASRKLGVQ 268
               +  + L F   A    +AL++F++G+  Y+ F+P GN + +  +    A +     
Sbjct: 191 IHSQQACYPLAFGVPAALMAVALIVFVLGSGMYKKFQPQGNIMGKVAKCIRFAIKN---- 246

Query: 269 MTSNGDDLYVIDEKESSNNSNRKILHTHGFKFLDRAAYITSRDLEVQKGGQHNPWYLCPI 328
                                         +F  R+     R+  +    +     L   
Sbjct: 247 ------------------------------RFRHRSKAFPKRNHWLDWAKEKYDERL--- 273

Query: 329 TQVEEVKCILRLLPIWLCTIIYSVVFTQMASLFVEQGAAMKTTISSFKIPPASMSSFDIL 388
             + ++K + +++ +++   ++  +F Q  S +  Q   M   I + +I P  M + + +
Sbjct: 274 --ISQIKIMTKVMFLYIPLPMFWALFDQQGSRWTLQATTMTGKIGTIEIQPDQMQTVNAI 331

Query: 389 SVAIFIFFYRRVLDPLVGKLKKSSSKGLTELQRMGIGLVIAIIAMVTAGIVE 440
            + I +     V+ PL+ K         T L++M +G+ +A +A V A IV+
Sbjct: 332 LIVIMVPIVDAVVYPLIAK----CGFNFTSLKKMTVGMFLASMAFVVAAIVQ 379



 Score = 40.4 bits (93), Expect = 0.013
 Identities = 21/72 (29%), Positives = 39/72 (54%)

Query: 441 CYRLKYAKQGDTSSLSIFWQIPQYALIGASEVFMYVGQLEFFNAQTPDGLKSFGSALCMT 500
           C  +K  +    +++++  QIPQY L+   EV   V  LEF  +Q P  +KS   A  + 
Sbjct: 567 CLEVKEFEDIPPNTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLL 626

Query: 501 SISLGNYVSSLI 512
           ++++GN +  ++
Sbjct: 627 TVAIGNIIVLIV 638


>PET1_RABIT (P36836) Oligopeptide transporter, small intestine
           isoform (Peptide transporter 1) (Intestinal H(+)/peptide
           cotransporter)
          Length = 707

 Score =  117 bits (292), Expect = 1e-25
 Identities = 95/413 (23%), Positives = 181/413 (43%), Gaps = 61/413 (14%)

Query: 37  ILLNQGLATLAFFGVGVNLVLFLTRVLGQDNAAAANNVSKWTGTVYIFSLVGAFLSDSYW 96
           I++N+     +++G+   L+L+    +G D+  +      +    Y+  ++GA ++D++ 
Sbjct: 19  IVVNEFCERFSYYGMRALLILYFRNFIGWDDNLSTVIYHTFVALCYLTPILGALIADAWL 78

Query: 97  GRYKTCAIFQGIFVTGLVSLSVTTYLALLRPKGCGNGKLECGEHSSLEMGMFYLSIYLIA 156
           G++KT      ++  G    S+++   L      G       +   + + +  + + LIA
Sbjct: 79  GKFKTIVWLSIVYTIGQAVTSLSSVNELTDNNHDGTP-----DSLPVHVAVCMIGLLLIA 133

Query: 157 LGNGGYQPNIATFGADQFDEDHSKESYSKVAFFSYFYLALNLGSLFSNTI--------LG 208
           LG GG +P ++ FG DQF+E   K+   +  FFS FYLA+N GSL S  I         G
Sbjct: 134 LGTGGIKPCVSAFGGDQFEEGQEKQ---RNRFFSIFYLAINAGSLLSTIITPMVRVQQCG 190

Query: 209 YFEDEGLWALGFWASAGSAFLALVLFLVGTPKYRHFKPCGNPLSRFCQ-VFFAASRKLGV 267
               +  + L F   A    ++L++F++G+  Y+ FKP GN LS+  + + FA   +   
Sbjct: 191 IHVKQACYPLAFGIPAILMAVSLIVFIIGSGMYKKFKPQGNILSKVVKCICFAIKNR--- 247

Query: 268 QMTSNGDDLYVIDEKESSNNSNRKILHTHGFKFLDRAAYITSRDLEVQKGGQHNPWYLCP 327
                                          +F  RA ++   D   +K  +        
Sbjct: 248 -------------------------FRHRSKQFPKRAHWL---DWAKEKYDER------- 272

Query: 328 ITQVEEVKCILRLLPIWLCTIIYSVVFTQMASLFVEQGAAMKTTISSFKIPPASMSSFDI 387
              + ++K + R+L +++   ++  +F Q  S +  Q   M   I   +I P  M + + 
Sbjct: 273 --LIAQIKMVTRVLFLYIPLPMFWALFDQQGSRWTLQATTMSGRIGILEIQPDQMQTVNT 330

Query: 388 LSVAIFIFFYRRVLDPLVGKLKKSSSKGLTELQRMGIGLVIAIIAMVTAGIVE 440
           + + I +     V+ PL+ K         T L++M IG+ +A +A V A I++
Sbjct: 331 ILIIILVPIMDAVVYPLIAK----CGLNFTSLKKMTIGMFLASMAFVAAAILQ 379



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 22/80 (27%), Positives = 45/80 (55%)

Query: 433 MVTAGIVECYRLKYAKQGDTSSLSIFWQIPQYALIGASEVFMYVGQLEFFNAQTPDGLKS 492
           ++T+    C ++   +    +++++ WQIPQY LI + EV   +  LEF  +Q P  +KS
Sbjct: 556 LITSQATGCPQVTEFEDIPPNTMNMAWQIPQYFLITSGEVVFSITGLEFSYSQAPSNMKS 615

Query: 493 FGSALCMTSISLGNYVSSLI 512
              A  + ++++GN +  ++
Sbjct: 616 VLQAGWLLTVAVGNIIVLIV 635


>PET2_RABIT (P46029) Oligopeptide transporter, kidney isoform
           (Peptide transporter 2) (Kidney H(+)/peptide
           cotransporter)
          Length = 729

 Score =  114 bits (284), Expect = 9e-25
 Identities = 103/411 (25%), Positives = 180/411 (43%), Gaps = 68/411 (16%)

Query: 37  ILLNQGLATLAFFGVGVNLVLFLTRVLGQDNAAAANNVSKWTGTVYIFSLVGAFLSDSYW 96
           I++N+     +++G+   L L+    L  +   + +    ++   Y   ++GA ++DS+ 
Sbjct: 49  IVVNEFCERFSYYGMKAVLTLYFLYFLHWNEDTSTSVYHAFSSLCYFTPILGAAIADSWL 108

Query: 97  GRYKTCAIFQGIFVTGLVSLSVTTYLALLRPKGCGNGKLECGEHSSLEMGMFYLSIYLIA 156
           G++KT      + V G V  S++ +  L        GK+    H+ L +    + + LIA
Sbjct: 109 GKFKTIIYLSLVNVLGHVIKSLSAFPIL-------GGKVV---HTVLSL----VGLCLIA 154

Query: 157 LGNGGYQPNIATFGADQFDEDHSKESYSKVAFFSYFYLALNLGSLFSNTILGYFE----- 211
           LG GG +P +A FG DQF+E H++E   +  +FS FYLA+N GSL S  I          
Sbjct: 155 LGTGGIKPCVAAFGGDQFEEKHAEE---RTRYFSGFYLAINAGSLISTFITPMLRGDVQC 211

Query: 212 -DEGLWALGFWASAGSAFLALVLFLVGTPKYRHFKPCGNPLSRFCQ-VFFAASRKLGVQM 269
             E  +AL F        +ALV+F +G+  Y+   P GN +++  + ++FA S       
Sbjct: 212 FGEDCYALAFGVPGLLMVIALVVFAMGSKMYKKPPPEGNIVAQVVKCIWFAISN------ 265

Query: 270 TSNGDDLYVIDEKESSNNSNRKILHTHGFKFLDRAAYITSRDLEVQKGGQHNPWYLCPIT 329
                                        +F +R+  I  R   +    +  P  L    
Sbjct: 266 -----------------------------RFKNRSEDIPKRQHWLDWAAEKYPKQL---- 292

Query: 330 QVEEVKCILRLLPIWLCTIIYSVVFTQMASLFVEQGAAMKTTISSFKIPPASMSSFDILS 389
            + +VK + R+L +++   ++  +  Q  S +  Q   M   +  F + P  M   + L 
Sbjct: 293 -IMDVKTLTRVLFLYIPLPMFWALLDQQGSRWTLQATKMNGNLGFFVLQPDQMQVLNPLL 351

Query: 390 VAIFIFFYRRVLDPLVGKLKKSSSKGLTELQRMGIGLVIAIIAMVTAGIVE 440
           V IFI  +  V+  L+ K         T L++M +G+V+A +A   A  VE
Sbjct: 352 VLIFIPLFDLVIYRLISK----CGINFTSLRKMAVGMVLACLAFAAAATVE 398



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 27/68 (39%), Positives = 41/68 (59%), Gaps = 4/68 (5%)

Query: 453 SSLSIFWQIPQYALIGASEVFMYVGQLEFFNAQTPDGLKSFGSALCMTSISLGNYVSSLI 512
           + +SI WQ+PQYAL+ A EV   V  LEF  +Q P  +KS   A  + ++++GN    +I
Sbjct: 604 NKVSIAWQLPQYALVTAGEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTVAIGN----II 659

Query: 513 VSIVMKIS 520
           V +V + S
Sbjct: 660 VLVVAQFS 667


>PET2_RAT (Q63424) Oligopeptide transporter, kidney isoform (Peptide
           transporter 2) (Kidney H(+)/peptide cotransporter)
          Length = 729

 Score =  112 bits (280), Expect = 3e-24
 Identities = 99/411 (24%), Positives = 182/411 (44%), Gaps = 68/411 (16%)

Query: 37  ILLNQGLATLAFFGVGVNLVLFLTRVLGQDNAAAANNVSKWTGTVYIFSLVGAFLSDSYW 96
           I++N+     +++G+   L L+    L  +   + +    ++   Y   ++GA ++DS+ 
Sbjct: 49  IVVNEFCERFSYYGMKAVLTLYFLYFLHWNEDTSTSVYHAFSSLCYFTPILGAAIADSWL 108

Query: 97  GRYKTCAIFQGIFVTGLVSLSVTTYLALLRPKGCGNGKLECGEHSSLEMGMFYLSIYLIA 156
           G++KT      ++V G V  S+     L        GK+    H+ L +    + + LIA
Sbjct: 109 GKFKTIIYLSLVYVLGHVFKSLGAIPIL-------GGKML---HTILSL----VGLSLIA 154

Query: 157 LGNGGYQPNIATFGADQFDEDHSKESYSKVAFFSYFYLALNLGSLFSNTILGYFEDE--- 213
           LG GG +P +A FG DQF+E+H++   ++  +FS FYLA+N GSL S  I      +   
Sbjct: 155 LGTGGIKPCVAAFGGDQFEEEHAE---ARTRYFSVFYLAINAGSLISTFITPMLRGDVKC 211

Query: 214 ---GLWALGFWASAGSAFLALVLFLVGTPKYRHFKPCGNPLSRFCQ-VFFAASRKLGVQM 269
                +AL F        LALV+F +G+  YR   P GN +++  + ++FA         
Sbjct: 212 FGQDCYALAFGVPGLLMVLALVVFAMGSKMYRKPPPEGNIVAQVIKCIWFALCN------ 265

Query: 270 TSNGDDLYVIDEKESSNNSNRKILHTHGFKFLDRAAYITSRDLEVQKGGQHNPWYLCPIT 329
                                        +F +R+  +  R   +    +  P +L    
Sbjct: 266 -----------------------------RFRNRSGDLPKRQHWLDWAAEKYPKHL---- 292

Query: 330 QVEEVKCILRLLPIWLCTIIYSVVFTQMASLFVEQGAAMKTTISSFKIPPASMSSFDILS 389
            + +VK + R+L +++   ++  +  Q  S +  Q   M   +  F + P  M   +   
Sbjct: 293 -IADVKALTRVLFLYIPLPMFWALLDQQGSRWTLQANKMNGDLGFFVLQPDQMQVLNPFL 351

Query: 390 VAIFIFFYRRVLDPLVGKLKKSSSKGLTELQRMGIGLVIAIIAMVTAGIVE 440
           V IFI  +  V+  L+ K + + S     L++M +G+++A +A   A +VE
Sbjct: 352 VLIFIPLFDLVIYRLISKCRINFS----SLRKMAVGMILACLAFAVAALVE 398



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 30/91 (32%), Positives = 52/91 (56%), Gaps = 7/91 (7%)

Query: 430 IIAMVTAGIVECYRLKYAKQGDTSSLSIFWQIPQYALIGASEVFMYVGQLEFFNAQTPDG 489
           +I  +T+  ++ ++   A+    + LSI WQ+PQY L+ A+EV   V  LEF  +Q P  
Sbjct: 584 VITNITSQGLQAWK---AEDIPVNKLSIAWQLPQYVLVTAAEVMFSVTGLEFSYSQAPSS 640

Query: 490 LKSFGSALCMTSISLGNYVSSLIVSIVMKIS 520
           +KS   A  + ++++GN    +IV +V + S
Sbjct: 641 MKSVLQAAWLLTVAVGN----IIVLVVAQFS 667


>PET2_HUMAN (Q16348) Oligopeptide transporter, kidney isoform
           (Peptide transporter 2) (Kidney H(+)/peptide
           cotransporter) (Solute carrier family 15, member 2)
          Length = 729

 Score =  109 bits (272), Expect = 2e-23
 Identities = 103/411 (25%), Positives = 180/411 (43%), Gaps = 68/411 (16%)

Query: 37  ILLNQGLATLAFFGVGVNLVLFLTRVLGQDNAAAANNVSKWTGTVYIFSLVGAFLSDSYW 96
           I++N+     +++G+   L+L+    L  +   + +    ++   Y   ++GA ++DS+ 
Sbjct: 49  IVVNEFCERFSYYGMKAVLILYFLYFLHWNEDTSTSIYHAFSSLCYFTPILGAAIADSWL 108

Query: 97  GRYKTCAIFQGIFVTGLVSLSVTTYLALLRPKGCGNGKLECGEHSSLEMGMFYLSIYLIA 156
           G++KT      ++V G V  S+     L        G++    H+ L +    + + LIA
Sbjct: 109 GKFKTIIYLSLVYVLGHVIKSLGALPIL-------GGQVV---HTVLSL----IGLSLIA 154

Query: 157 LGNGGYQPNIATFGADQFDEDHSKESYSKVAFFSYFYLALNLGSLFSNTILGYFE----- 211
           LG GG +P +A FG DQF+E H++E   +  +FS FYL++N GSL S  I          
Sbjct: 155 LGTGGIKPCVAAFGGDQFEEKHAEE---RTRYFSVFYLSINAGSLISTFITPMLRGDVQC 211

Query: 212 -DEGLWALGFWASAGSAFLALVLFLVGTPKYRHFKPCGNPLSR-FCQVFFAASRKLGVQM 269
             E  +AL F        +ALV+F +G+  Y    P GN +++ F  ++FA S +     
Sbjct: 212 FGEDCYALAFGVPGLLMVIALVVFAMGSKIYNKPPPEGNIVAQVFKCIWFAISNRF---- 267

Query: 270 TSNGDDLYVIDEKESSNNSNRKILHTHGFKFLDRAAYITSRDLEVQKGGQHNPWYLCPIT 329
                            N +  I   H   +LD AA    + L                 
Sbjct: 268 ----------------KNRSGDIPKRH--DWLDWAAEKYPKQL----------------- 292

Query: 330 QVEEVKCILRLLPIWLCTIIYSVVFTQMASLFVEQGAAMKTTISSFKIPPASMSSFDILS 389
            + +VK + R+L +++   ++  +  Q  S +  Q   M   +  F + P  M   + L 
Sbjct: 293 -IMDVKALTRVLFLYIPLPMFWALLDQQGSRWTLQAIRMNRNLGFFVLQPDQMQVLNPLL 351

Query: 390 VAIFIFFYRRVLDPLVGKLKKSSSKGLTELQRMGIGLVIAIIAMVTAGIVE 440
           V IFI  +  V+  LV K         + L++M +G+++A +A   A  VE
Sbjct: 352 VLIFIPLFDFVIYRLVSK----CGINFSSLRKMAVGMILACLAFAVAARVE 398



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 28/68 (41%), Positives = 41/68 (60%), Gaps = 4/68 (5%)

Query: 453 SSLSIFWQIPQYALIGASEVFMYVGQLEFFNAQTPDGLKSFGSALCMTSISLGNYVSSLI 512
           + +SI WQ+PQYAL+ A EV   V  LEF  +Q P  +KS   A  + +I++GN    +I
Sbjct: 604 NKMSIRWQLPQYALVTAGEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTIAVGN----II 659

Query: 513 VSIVMKIS 520
           V +V + S
Sbjct: 660 VLVVAQFS 667


>OPT1_DROME (P91679) Oligopeptide transporter 1 (YIN protein)
          Length = 737

 Score =  105 bits (263), Expect = 2e-22
 Identities = 101/412 (24%), Positives = 172/412 (41%), Gaps = 76/412 (18%)

Query: 37  ILLNQGLATLAFFGVGVNLVLFLTRVLGQDNAAAANNVSKWTGTVYIFSLVGAFLSDSYW 96
           I+ N+      ++G+   LVL+LT  LG +   A      +T  VYIF L+GA ++D + 
Sbjct: 33  IISNEFCERFNYYGMRTILVLYLTNKLGYNEETATVLFHTFTMLVYIFPLIGALIADGWL 92

Query: 97  GRYKTCAIFQGIFVTGLVSLSVTTYLALLRPKGCGNGKLECGEHSSLEMGMFYLSIYLIA 156
           G+YKT      ++  G + +S         P                   +  + + LIA
Sbjct: 93  GKYKTILYLSLVYSLGAMVVSFGAVPLSGMP----------------TKAVTVVGLLLIA 136

Query: 157 LGNGGYQPNIATFGADQFDEDHSKESYSKVAFFSYFYLALNLGSLFSNTI-------LGY 209
           +GNGG  P ++ FG +QF      +S+    FFS FY A+N GSL S T        +  
Sbjct: 137 IGNGGINPCVSPFGGEQF--SLPAQSFQLAKFFSLFYFAINAGSLISTTFTPILRADVHC 194

Query: 210 FEDEGLWALGFWASAGSAFLALVLFLVGTPKYRHFKPCGNPLSRFCQVFFAASRKLGVQM 269
           F D+  ++L F   A     ++++F+ G   YR   P GN       + F  SR +    
Sbjct: 195 FGDQDCFSLAFGVPAILMIFSVIIFMAGKRLYRCQPPAGN-------MIFGVSRCIA--- 244

Query: 270 TSNGDDLYVIDEKESSNNSNRKILHTHGFKFLDRA-AYITSRDLEVQKGGQHNPWYLCPI 328
                D +   +K   +             FLD A   + SR                  
Sbjct: 245 -----DAFKGWQKRRHSEPME--------SFLDYAKPTVGSR------------------ 273

Query: 329 TQVEEVKCILRLLPIWLCTIIYSVVFTQMASLFVEQGAAMKTTISSFKIPPASMSSFDIL 388
             V+E KC+ R+L ++L   ++  +F Q  S +  Q   M   +  F+I P  M   + L
Sbjct: 274 -MVQETKCLGRILRLFLPFPVFWALFDQQGSRWTFQATRMDGNVLGFQIKPDQMQVVNPL 332

Query: 389 SVAIFIFFYRRVLDPLVGKLKKSSSKGLTE-LQRMGIGLVIAIIA-MVTAGI 438
            +  F+  +  ++ P + +       G+   LQ++ +G ++A +   ++AG+
Sbjct: 333 LILGFLPLFDYIIYPALARC------GIRRPLQKLTLGFLLAALGFFLSAGL 378



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 35/145 (24%), Positives = 69/145 (47%), Gaps = 17/145 (11%)

Query: 433 MVTAGIVECYRLKYAKQGDTSSLSIFWQIPQYALIGASEVFMYVGQLEFFNAQTPDGLKS 492
           +VT    + Y+    +    S++SI WQ+PQ  ++ A+EV   V  LEF  +Q+P  +KS
Sbjct: 563 LVTGSARDGYQHNVIEVVAPSTVSILWQLPQIVVMTAAEVMFSVTGLEFSYSQSPPSMKS 622

Query: 493 FGSALCMTSISLGNYVSSLIVSIVMKISTEDHMPGWIPGNLNRGHLDRFFFLLAVLTSLD 552
              A  + S+++GN    ++V ++ +        G              F L A L  +D
Sbjct: 623 VLQACWLLSVAIGN----MLVVVIAEFKFTSSQSG-------------EFTLFASLMLVD 665

Query: 553 LIAYIACAKWFQNIQMACKYDNNDE 577
           ++ ++  A+ +Q       ++++D+
Sbjct: 666 MMIFLWLARSYQYKDQREDFEDDDD 690


>OPT1_CAEEL (Q17758) Oligopeptide transporter 1 (Di-/tri-peptide
           transporter CPTA)
          Length = 785

 Score =  102 bits (255), Expect = 2e-21
 Identities = 97/444 (21%), Positives = 190/444 (41%), Gaps = 59/444 (13%)

Query: 30  RWFAGTIILLNQGLAT-LAFFGVGVNLVLFLTRVLGQDNAAAANNVSKWTGTVYIFSLVG 88
           +W   T +++   L    +F+G+   L L+   +L    + +      +T   Y   L+G
Sbjct: 29  KWPKQTFLIVGNELCERFSFYGMRAVLTLYFFNILNFSQSFSTVLFHAFTVICYSSPLLG 88

Query: 89  AFLSDSYWGRYKTCAIFQGIFVTGLVSLSVTTYLALLRPKGCGNGKLECGEHSSLEMGMF 148
           + L+D Y G++ T       +  G + L+ ++    + P G  +       H  L++   
Sbjct: 89  SILADGYIGKFWTIFFISIFYACGQILLAFSS----IAPSGSSH-------HPLLDL--- 134

Query: 149 YLSIYLIALGNGGYQPNIATFGADQFDEDHSKESYSKVAFFSYFYLALNLGSLFSNTILG 208
            L + ++ LG GG +P ++ FG DQF   +++       FFS FY ++N GSL S  +  
Sbjct: 135 -LGLLIVGLGTGGIKPCVSAFGGDQFPAHYTR---MISLFFSMFYFSINAGSLISMWLTP 190

Query: 209 YFED------EGLWALGFWASAGSAFLALVLFLVGTPKYRHFKPCGNPLSRFCQVFFAAS 262
           YF        +  + L F   A    +A ++F+ G+  Y+   P  N + +       A 
Sbjct: 191 YFRSMSCFGHDSCYPLAFGIPAILMIVATLVFMAGSFWYKKVPPKENIIFKVIGTITTAL 250

Query: 263 RKLGVQMTSNGDDLYVIDEKESSNNSNRKILHTHGFKF-LDRAAYITSRDLEVQKGGQHN 321
           RK                 K SS++++++   +H  ++ LD      S + +   G    
Sbjct: 251 RK-----------------KASSSSTHQR---SHWLEYSLDGHDCALSTECKNLHGNCAQ 290

Query: 322 PWYLCPITQVEEVKCILRLLPIWLCTIIYSVVFTQMASLFVEQGAAMKTTISSFKIPPAS 381
             Y      +E++K + R++ + +   ++  ++ Q  S +V Q   M   +  F+I P  
Sbjct: 291 RRY------IEDIKRLFRVIVMMIPVPMFWALYDQQGSTWVLQAVGMDAKVFGFEILPDQ 344

Query: 382 MSSFDILSVAIFIFFYRRVLDPLVGKLKKSSSKGLTELQRMGIGLVIAIIAMVTAGIVEC 441
           M   +   +  FI  ++ ++ P + KL       +T L++M  G ++  ++    GIV+ 
Sbjct: 345 MGVLNAFLILFFIPIFQSIVYPTIEKL----GFQMTMLRKMAGGGILTAVSFFVCGIVQL 400

Query: 442 Y---RLKYAKQGDTSSLSIFWQIP 462
           +    L Y    + + L+I   IP
Sbjct: 401 FVNPTLPYIPMANEAHLTIINTIP 424



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 21/58 (36%), Positives = 33/58 (56%)

Query: 455 LSIFWQIPQYALIGASEVFMYVGQLEFFNAQTPDGLKSFGSALCMTSISLGNYVSSLI 512
           +SI WQIPQY ++ A EV   +  LEF   +    LKS   AL + + ++G+ +  +I
Sbjct: 668 VSILWQIPQYVILTAGEVLFSITGLEFAYTEASPQLKSVVQALWLFTTAIGDLIVVVI 725


>PTR2_SCHPO (Q9P380) Probable peptide transporter Ptr2 (Peptide
           permease Ptr2)
          Length = 618

 Score = 95.5 bits (236), Expect = 3e-19
 Identities = 115/473 (24%), Positives = 196/473 (41%), Gaps = 85/473 (17%)

Query: 63  LGQDNAAAANNVSKWTGTVYIFSLVGAFLSDSYWGRYKTCAIFQGIFVTGLVSLSVTTYL 122
           LG+  A   +N   +T   Y+  +  A ++D + GRY T      I+  G++ L+ T   
Sbjct: 124 LGESGADGLSNF--FTFWCYVTPVGAALIADQFLGRYNTIVCSAVIYFIGILILTCTAI- 180

Query: 123 ALLRPKGCGNGKLECGEHSSLEMGMFYLSIYLIALGNGGYQPNIATFGADQFDED----H 178
               P     GK          MG F +S+ +I LG GG + N++   A+Q  +      
Sbjct: 181 ----PSVIDAGK---------SMGGFVVSLIIIGLGTGGIKSNVSPLMAEQLPKIPPYVK 227

Query: 179 SKESYSKVAF---------FSYFYLALNLGSLFSNTILGYFEDEGLWALGFWASAGSAFL 229
           +K++ SKV           +  FY ++N+GSL           +G +   +        +
Sbjct: 228 TKKNGSKVIVDPVVTTSRAYMIFYWSINVGSLSVLATTSLESTKG-FVYAYLLPLCVFVI 286

Query: 230 ALVLFLVGTPKYRHFKPCGNPLSRFCQVFF-AASRKLGVQMTSNGDDLYVIDEKESSNNS 288
            L++  V    Y+H  P G+   R  QVFF AA  K  ++ T           K S   +
Sbjct: 287 PLIILAVSKRFYKHTPPSGSIFVRVGQVFFLAAQNKFNLEKT-----------KPSCTTT 335

Query: 289 NRKILHTHGFKFLDRAAYITSRDLEVQKGGQHNPWYLCPITQVEEVKCILRLLPIWLCTI 348
                             +T +D       Q +  +      ++E+K  LR    +L   
Sbjct: 336 ---------------VGRVTLKD-------QWDDLF------IDELKRALRACKTFLFYP 367

Query: 349 IYSVVFTQMASLFVEQGAAMKTTISSFKIPPASMSSFDILSVAIFIFFYRRVLDPLVGKL 408
           IY V + QM +  + Q   M+T   S  +      +FD +++ IFI     ++ PL+ K 
Sbjct: 368 IYWVCYGQMTNNLISQAGQMQTGNVSNDL----FQAFDSIALIIFIPICDNIIYPLLRKY 423

Query: 409 KKSSSKGLTELQRMGIGLVIAIIAMVTAGIVECYRLK----YAKQGDT---SSLSIFWQI 461
                     + R+ +G + A  +M+ A +++    +    YA   DT   + +S++ QI
Sbjct: 424 NIP----FKPILRITLGFMFATASMIYAAVLQAKIYQRGPCYANFTDTCVSNDISVWIQI 479

Query: 462 PQYALIGASEVFMYVGQLEFFNAQTPDGLKSFGSALCMTSISLGNYVSSLIVS 514
           P Y LI  SE+F  +  LEF   + P  +KS  +AL + + + G  +S  I S
Sbjct: 480 PAYVLIAFSEIFASITGLEFAFTKAPPSMKSIITALFLFTNAFGAILSICISS 532


>OPT3_CAEEL (O01840) Putative oligopeptide transporter opt-3
          Length = 701

 Score = 91.7 bits (226), Expect = 5e-18
 Identities = 93/412 (22%), Positives = 173/412 (41%), Gaps = 71/412 (17%)

Query: 37  ILLNQGLATLAFFGVGVNLVLFLTRVLGQDNAAAANNVSKWTGTVYIFSLVGAFLSDSYW 96
           +L N+     +F+G+   L ++L        + A      +T   Y+  L+G+ ++DS +
Sbjct: 20  MLGNEFCERFSFYGMKTILFIYLITEHEFSPSKATFIYHLFTCIAYLTPLIGSIMADSVF 79

Query: 97  GRYKTCAIFQGIFVTGLVSLSVTTYLALLRPKGCGNGKLECGEHSSLEMGMFYLSIYLIA 156
           GR+K       I+V G V LS+     L  P               +   + +  +++IA
Sbjct: 80  GRFKVILYGSSIYVVGHVLLSLGAVPFLSYP---------------IRSSLDFSGLFVIA 124

Query: 157 LGNGGYQPNIATFGADQFDEDHSKESYSKVAFFSYFYLALNLGSLFSNTI-------LGY 209
              G  +P ++ F ADQF ED  K+  S+  FFS+FY A+N GSLF+  I       +  
Sbjct: 125 FATGCIKPCVSAFAADQFTED-QKDLRSQ--FFSFFYFAINGGSLFAIIITPILRGRVQC 181

Query: 210 FEDEGLWALGFWASAGSAFLALVLFLVGTPKYRHFKPC-GNPLSRFCQVFFAASRKLGVQ 268
           F +   + L F        LAL+LFL+G   Y+   P   N  S+   V + + RK+   
Sbjct: 182 FGNAHCFPLAFGVPGVLMLLALILFLMGWSMYKKHPPSKENVGSKVVAVIYTSLRKM--- 238

Query: 269 MTSNGDDLYVIDEKESSNNSNRKILHTHGFKFLDRAAYITSRDLEVQKGGQHNPWYLCPI 328
                             + ++ + H     +LD AA   S+ +                
Sbjct: 239 --------------VGGASRDKPVTH-----WLDHAAPEHSQKM---------------- 263

Query: 329 TQVEEVKCILRLLPIWLCTIIYSVVFTQMASLFVEQGAAMKTTISSFKIPPASMSSFDIL 388
             ++  + +L +  I+   I +  +F Q  S +V Q   +   +  F I P  + + + +
Sbjct: 264 --IDSTRGLLNVAVIFCPLIFFWALFDQQGSTWVLQARRLDGRVGHFSILPEQIHAINPV 321

Query: 389 SVAIFIFFYRRVLDPLVGKLKKSSSKGLTELQRMGIGLVIAIIAMVTAGIVE 440
            V I +  +   + P + K+ +     +T L++M +G ++   +   AG+++
Sbjct: 322 CVLILVPIFEGWVYPALRKITR-----VTPLRKMAVGGLLTAFSFAIAGVLQ 368



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 21/60 (35%), Positives = 35/60 (58%)

Query: 453 SSLSIFWQIPQYALIGASEVFMYVGQLEFFNAQTPDGLKSFGSALCMTSISLGNYVSSLI 512
           +S+SI W +PQY +I   EV + V  LEF  +Q    +KS  +A+ + ++  GN +  +I
Sbjct: 571 NSVSILWSLPQYIIITLGEVLLSVTGLEFAYSQAAPNMKSVLTAMWLLTVFAGNLIDMMI 630


>OPT2_CAEEL (Q21219) Oligopeptide transporter 2 (Di-/tri-peptide
           transporter CPTB)
          Length = 835

 Score = 91.3 bits (225), Expect = 6e-18
 Identities = 95/415 (22%), Positives = 182/415 (42%), Gaps = 58/415 (13%)

Query: 37  ILLNQGLATLAFFGVGVNLVLFLTRVLGQDNAAAANNVSKWTGTVYIFSLVGAFLSDSYW 96
           I+ N+     +++G+   L  +L  VL   ++ +    + +T   Y   L+G+ ++D Y 
Sbjct: 51  IVSNEFCERFSYYGMRTVLTFYLLNVLKFTDSQSTIFFNGFTVLCYTTPLLGSIVADGYI 110

Query: 97  GRYKTCAIFQGIFVTGLVSLSVTTYLALLRPKGCGNGKLECGEHSSLEMGMFYLSIYLIA 156
           G++ T      ++  G V       LAL   K            SS+   M    + +IA
Sbjct: 111 GKFWTIFSVSILYAIGQV------VLALASTKNF---------QSSVHPWMDLSGLLIIA 155

Query: 157 LGNGGYQPNIATFGADQFDEDHSKESYSKVAFFSYFYLALNLGSLFSNTILGYFE----- 211
            G GG +P ++ FG DQF+    +       FFS FY ++N GS+ S  I   F      
Sbjct: 156 FGTGGIKPCVSAFGGDQFELGQER---MLSLFFSMFYFSINAGSMISTFISPIFRSQPCL 212

Query: 212 -DEGLWALGFWASAGSAFLALVLFLVGTPKYRHFKPCGNPLSRFCQVFFAASRKLGVQMT 270
             +  + + F   A    +A ++F+ G+  Y+   P  N      ++ F   R +G +M 
Sbjct: 213 GQDSCYPMAFGIPAILMIVATLVFMGGSFWYKKNPPKDNVFGEVSRLMF---RAVGNKM- 268

Query: 271 SNGDDLYVIDEKESSNNSNRKILH---THGFKFLDRAAYITSRDLEVQKGGQHNPWYLCP 327
                      K  S      +LH   TH     D A      +L+ +K  ++    LC 
Sbjct: 269 -----------KSGSTPKEHWLLHYLTTH-----DCALDAKCLELQAEKRNKN----LCQ 308

Query: 328 ITQ-VEEVKCILRLLPIWLCTIIYSVVFTQMASLFVEQGAAMKTTIS-SFKIPPASMSSF 385
             + +++V+ +LR+L ++L   ++  ++ Q  S+++ Q   M   +S +  + P  M + 
Sbjct: 309 KKKFIDDVRSLLRVLVMFLPVPMFWALYDQQGSVWLIQAIQMDCRLSDTLLLLPDQMQTL 368

Query: 386 DILSVAIFIFFYRRVLDPLVGKLKKSSSKGLTELQRMGIGLVIAIIAMVTAGIVE 440
           + + + +FI  ++ ++ P+  K  +     LT L++M  G ++A +A +  G V+
Sbjct: 369 NAVLILLFIPLFQVIIYPVAAKCVR-----LTPLRKMVTGGLLASLAFLITGFVQ 418



 Score = 40.0 bits (92), Expect = 0.017
 Identities = 22/66 (33%), Positives = 39/66 (58%), Gaps = 3/66 (4%)

Query: 452 TSSLSIFWQIPQYALIGASEVFMYVGQLEFFNAQTPDGLKSFGSALCMTSISLGNYVSSL 511
           ++S+SI WQIPQ  +I A+E+   +   EF  +Q+   +K+   AL + + + G+   S+
Sbjct: 692 SNSVSILWQIPQIVVITAAEILFSITGYEFAYSQSAPSMKALVQALWLLTTAAGD---SI 748

Query: 512 IVSIVM 517
           IV I +
Sbjct: 749 IVVITI 754


>PTR2_YEAST (P32901) Peptide transporter PTR2 (Peptide permease
           PTR2)
          Length = 601

 Score = 87.4 bits (215), Expect = 9e-17
 Identities = 97/462 (20%), Positives = 185/462 (39%), Gaps = 99/462 (21%)

Query: 82  YIFSLVGAFLSDSYWGRYKTCAIFQGIFVTGLVSLSVTTYLALLRPKGCGNGKLECGEHS 141
           Y+  + G +++D++WG+Y T      I++ G+  L +T+  ++             G   
Sbjct: 138 YVTPVFGGYVADTFWGKYNTICCGTAIYIAGIFILFITSIPSV-------------GNRD 184

Query: 142 SLEMGMFYLSIYLIALGNGGYQPNIATFGADQFDEDHSKESYSKVA-------------F 188
           S  +G F  +I LI +  G  + N++   ADQ  +        K                
Sbjct: 185 SA-IGGFIAAIILIGIATGMIKANLSVLIADQLPKRKPSIKVLKSGERVIVDSNITLQNV 243

Query: 189 FSYFYLALNLGSL--FSNTILGYFEDEGLWALGFWASAGSAF----LALVLFLVGTPKYR 242
           F +FY  +N+GSL   + T L Y +       GFWA+    F    +A+V  + G  +Y 
Sbjct: 244 FMFFYFMINVGSLSLMATTELEYHK-------GFWAAYLLPFCFFWIAVVTLIFGKKQYI 296

Query: 243 HFKPCGNPLSRFCQVFFAASRKLGVQMTSNGDDLYVIDEKESSNNSNRKILHTHGFKFLD 302
             +P G+ +        A S K+   +T N  D           N+ +  +H        
Sbjct: 297 Q-RPIGDKV-------IAKSFKVCWILTKNKFDF----------NAAKPSVHPE------ 332

Query: 303 RAAYITSRDLEVQKGGQHNPWYLCPITQVEEVKCILRLLPIWLCTIIYSVVFTQMASLFV 362
                           ++ PW       V+E+K  L    +++   IY   +  M S F+
Sbjct: 333 ----------------KNYPWN---DKFVDEIKRALAACKVFIFYPIYWTQYGTMISSFI 373

Query: 363 EQGAAMKTTISSFKIPPASMSSFDILSVAIFIFFYRRVLDPLVGKLKKSSSKGLTELQRM 422
            Q + M+       IP   + +FD +++ IFI  + + + P + +        L  + ++
Sbjct: 374 TQASMMEL----HGIPNDFLQAFDSIALIIFIPIFEKFVYPFIRRYTP-----LKPITKI 424

Query: 423 GIGLVIAIIAMVTAGIVECYRLKYAK-------QGDTSSLSIFWQIPQYALIGASEVFMY 475
             G +    AM  A +++ +  K              + + + WQIP Y LI  SE+F  
Sbjct: 425 FFGFMFGSFAMTWAAVLQSFVYKAGPWYNEPLGHNTPNHVHVCWQIPAYVLISFSEIFAS 484

Query: 476 VGQLEFFNAQTPDGLKSFGSALCMTSISLGNYVSSLIVSIVM 517
           +  LE+  ++ P  +KSF  ++ + + + G+ +   +  + +
Sbjct: 485 ITGLEYAYSKAPASMKSFIMSIFLLTNAFGSAIGCALSPVTV 526


>YBGH_ECOLI (P75742) Hypothetical transporter ybgH
          Length = 493

 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 48/197 (24%), Positives = 82/197 (41%), Gaps = 26/197 (13%)

Query: 47  AFFGVGVNLVLFLTRVLGQDNAAAANNVSKWTGTVYIFSLVGAFLSDSYWGRYKTCAIFQ 106
           +F+G+   L+L+LT  L  ++  A    S +   VY+  ++G FL+D   G      +  
Sbjct: 24  SFYGMRALLILYLTNQLKYNDTHAYELFSAYCSLVYVTPILGGFLADKVLGNRMAVMLGA 83

Query: 107 GIFVTGLVSLSVTTYLALLRPKGCGNGKLECGEHSSLEMGMFYLSIYLIALGNGGYQPNI 166
            +   G V L                        S +     YLS+ +I  G G ++ N+
Sbjct: 84  LLMAIGHVVLGA----------------------SEIHPSFLYLSLAIIVCGYGLFKSNV 121

Query: 167 ATFGADQFDEDHSKESYSKVAFFSYFYLALNLGSLFSNTILGYFEDEGLWALGFWASAGS 226
           +    + ++    +        FS  Y A N+GS+ +    GY ++E  WA+GF  +A  
Sbjct: 122 SCLLGELYEPTDPRRDGG----FSLMYAAGNVGSIIAPIACGYAQEEYSWAMGFGLAAVG 177

Query: 227 AFLALVLFLVGTPKYRH 243
               LV+FL G   + H
Sbjct: 178 MIAGLVIFLCGNRHFTH 194


>YJDL_ECOLI (P39276) Hypothetical transporter yjdL
          Length = 485

 Score = 68.2 bits (165), Expect = 6e-11
 Identities = 56/201 (27%), Positives = 96/201 (46%), Gaps = 33/201 (16%)

Query: 47  AFFGVGVNLVLFLTRVLGQDNAAAANNVSKWTGTVYIFSLVGAFLSDSYWGRYKTCAIFQ 106
           +F+G+   L+L+LT  LG D+  A +  S +   VY+  ++G +L+D   G  +T  I  
Sbjct: 23  SFYGMRALLILYLTHQLGFDDNHAISLFSAYASLVYVTPILGGWLADRLLGN-RTAVIAG 81

Query: 107 GIFVT-GLVSLSVTTYLALLRPKGCGNGKLECGEHSSLEMGMFYLSIYLIALGNGGYQPN 165
            + +T G V L + T                   +S+  +   YL++ +I  G G ++ N
Sbjct: 82  ALLMTLGHVVLGIDT-------------------NSTFSL---YLALAIIICGYGLFKSN 119

Query: 166 IATFGADQFDE-DHSKESYSKVAFFSYFYLALNLGSLFSNTILGYFEDEGLWALGFWASA 224
           I+    + +DE DH ++       FS  Y A N+GS+ +    G       W +GF  + 
Sbjct: 120 ISCLLGELYDENDHRRD-----GGFSLLYAAGNIGSIAAPIACGLAAQWYGWHVGFALAG 174

Query: 225 GSAFLALVLFLVGTPKYRHFK 245
           G  F+ L++FL G   +RHF+
Sbjct: 175 GGMFIGLLIFLSG---HRHFQ 192


>YCLF_BACSU (P94408) Hypothetical transporter yclF
          Length = 492

 Score = 64.3 bits (155), Expect = 8e-10
 Identities = 50/172 (29%), Positives = 85/172 (49%), Gaps = 27/172 (15%)

Query: 63  LGQDNAAAANNVSKWTGTVYIFSLVGAFLSDSYWGRYKTCAIFQGIFVTGLVSLSVTTYL 122
           LG D   A   +S +   VY+ +++G +L+D  +G   T   + GIF+       +  ++
Sbjct: 59  LGFDKGTAVAIMSIYGSLVYMSTIIGGWLADRVFGTANT-VFYGGIFI-------MFGHI 110

Query: 123 ALLRPKGCGNGKLECGEHSSLEMGMFYLSIYLIALGNGGYQPNIATFGADQFDEDHSKES 182
           AL  P             SS+    FY+S+ LI +G G  +PN+++   D +    +KE 
Sbjct: 111 ALAYPG------------SSIA---FYISMVLIIVGTGLLKPNVSSVVGDLY----TKED 151

Query: 183 YSKVAFFSYFYLALNLGSLFSNTILGYFEDEGLWALGFWASAGSAFLALVLF 234
             + + FS FY+ +NLG L +  I+G    +  + LGF A+A    L L++F
Sbjct: 152 PRRDSGFSIFYMGINLGGLLAPLIVGTLGQKYNYHLGFGAAAVGMLLGLIVF 203


>PT2A_ARATH (P46031) Peptide transporter PTR2-A
          Length = 610

 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 53/191 (27%), Positives = 92/191 (47%), Gaps = 15/191 (7%)

Query: 331 VEEVKCILRLLPIWLCTIIYSVVFTQMASLFVEQGAAMKTTISSFKIPPASMSSFDILSV 390
           ++E+K  LR    +L   IY V + QM +  + Q   M+T   S  +      +FD +++
Sbjct: 350 IDELKRALRACKTFLFYPIYWVCYGQMTNNLISQAGQMQTGNVSNDL----FQAFDSIAL 405

Query: 391 AIFIFFYRRVLDPLVGKLKKSSSKGLTELQRMGIGLVIAIIAMVTAGIVECYRLK----Y 446
            IFI     ++ PL+ K           + R+ +G + A  +M+ A +++    +    Y
Sbjct: 406 IIFIPICDNIIYPLLRKYNIP----FKPILRITLGFMFATASMIYAAVLQAKIYQRGPCY 461

Query: 447 AKQGDT---SSLSIFWQIPQYALIGASEVFMYVGQLEFFNAQTPDGLKSFGSALCMTSIS 503
           A   DT   + +S++ QIP Y LI  SE+F  +  LEF   + P  +KS  +AL + + +
Sbjct: 462 ANFTDTCVSNDISVWIQIPAYVLIAFSEIFASITGLEFAFTKAPPSMKSIITALFLFTNA 521

Query: 504 LGNYVSSLIVS 514
            G  +S  I S
Sbjct: 522 FGAILSICISS 532



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 41/152 (26%), Positives = 67/152 (43%), Gaps = 29/152 (19%)

Query: 63  LGQDNAAAANNVSKWTGTVYIFSLVGAFLSDSYWGRYKTCAIFQGIFVTGLVSLSVTTYL 122
           LG+  A   +N   +T   Y+  +  A ++D + GRY T      I+  G++ L+ T   
Sbjct: 124 LGETGADGLSNF--FTFWCYVTPVGAALIADQFLGRYNTIVCSAVIYFIGILILTCTAI- 180

Query: 123 ALLRPKGCGNGKLECGEHSSLEMGMFYLSIYLIALGNGGYQPNIATFGADQFDE----DH 178
               P     GK          MG F +S+ +I LG GG + N++   A+Q  +      
Sbjct: 181 ----PSVIDAGK---------SMGGFVVSLIIIGLGTGGIKSNVSPLMAEQLPKIPPYVK 227

Query: 179 SKESYSKVAF---------FSYFYLALNLGSL 201
           +K++ SKV           +  FY  +N+GSL
Sbjct: 228 TKKNGSKVIVDPVVTTSRAYMIFYWTINVGSL 259


>DTPT_LACLA (P36574) Di-/tripeptide transporter
          Length = 497

 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 103/500 (20%), Positives = 198/500 (39%), Gaps = 86/500 (17%)

Query: 47  AFFGVGVNLVLFLTRVLGQDNAA-------AANNVSKWTGTVYIFSLVGAFLSDSYWGRY 99
           +++G+   LV +L  +   DNA        A   VS +   VY+ ++VG +++D   G  
Sbjct: 31  SYYGMRAILVYYLYALTTADNAGLGLPKAQAMAIVSIYGALVYLSTIVGGWVADRLLGAS 90

Query: 100 KTCAIFQGIFVTGLVSLSVTTYLALLRPKGCGNGKLECGEHSSLEMGMFYLSIYLIALGN 159
           +T      IF+ G+  L    ++AL  P G               +   +++++LI LG 
Sbjct: 91  RT------IFLGGI--LITLGHIALATPFG---------------LSSLFVALFLIILGT 127

Query: 160 GGYQPNIATFGADQFDEDHSKESYSKVAFFSYFYLALNLGSLFSNTILGYFEDEGLWALG 219
           G  +PNI+      + +D S+        F+ F + +N+GSL +  I+G       + LG
Sbjct: 128 GMLKPNISNMVGHLYSKDDSRRDTG----FNIFVVGINMGSLIAPLIVGTVGQGVNYHLG 183

Query: 220 FWASAGSAFLALVLFLVGTPKYRHFKPCG----NPLSRFCQVFFAASRKLGVQMTSNGDD 275
           F  +A     AL  +  G  + RHF   G    NP+    +  F  +  + V +   G  
Sbjct: 184 FSLAAIGMIFALFAYWYG--RLRHFPEIGREPSNPMDSKARRNFLITLTIVVIVAIIGFF 241

Query: 276 LYVIDEKESSNNSNRKILHTHGF--KFLDRAAYITSRDLEVQKGGQHNPWYLCPITQVEE 333
           L       +  N+   +L   G     +      TS+ +E                  +E
Sbjct: 242 LLYQASPANFINNFINVLSIIGIVVPIIYFVMMFTSKKVE-----------------SDE 284

Query: 334 VKCILRLLPIWLCTIIYSVVFTQMASLFVEQGAAMKTTIS-----SFKIPPASMSSFDIL 388
            + +   +P++L  I++  +  Q +++    G +           +F I P   S + +L
Sbjct: 285 RRKLTAYIPLFLSAIVFWAIEEQSSTIIAVWGESRSNLDPTWFGITFHIDP---SWYQLL 341

Query: 389 SVAIFIFFYRRVLDPLVGKL-KKSSSKGLTELQRMGIGLV---IAIIAMVTAGIVECYRL 444
           +    +     +L P+  +L  K   +  + + + G+GL+   I+ + M   G++     
Sbjct: 342 NPLFIV-----LLSPIFVRLWNKLGERQPSTIVKFGLGLMLTGISYLIMTLPGLL----- 391

Query: 445 KYAKQGDTSSLSIFWQIPQYALIGASEVFMYVGQLEFFNAQTPDGLKSFGSALCMTSISL 504
                G +   S  W +  +A+  A E+ +    L       P   +S   A+   + S 
Sbjct: 392 ----NGTSGRASALWLVLMFAVQMAGELLVSPVGLSVSTKLAPVAFQSQMMAMWFLADST 447

Query: 505 GNYVSSLIVSIVMKISTEDH 524
              +++ I  +  K +TE H
Sbjct: 448 SQAINAQITPL-FKAATEVH 466


>DTPT_LACHE (O07380) Di-/tripeptide transporter
          Length = 497

 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 53/188 (28%), Positives = 84/188 (44%), Gaps = 36/188 (19%)

Query: 63  LGQDNAAAANNVSKWTGTVYIFSLVGAFLSDSYWGRYKTCAIFQGIFVTGLVSLSVTTYL 122
           LG     AA+ +S +   VY+ +LVG +LSD  WG  KT      +F  G+  L +  ++
Sbjct: 18  LGMSQTTAASIMSIYGSLVYLSTLVGGWLSDRVWGSRKT------VFYGGV--LIMLGHI 69

Query: 123 ALLRPKGCGNGKLECGEHSSLEMGMFYLSIYLIALGNGGYQPNIATFGADQFDEDHSKES 182
            L  P G               + + Y SI LI +G G  +PN+    +D     +S E 
Sbjct: 70  VLALPAG---------------VTVLYRSIALIVVGTGLLKPNV----SDMVGGLYSVED 110

Query: 183 YSKVAFFSYFYLALNLGSLFSNTILGY---------FEDEGLWALGFWASAGSAFLALVL 233
             + A FS F   +NLGS+ +  ++ +         F  +  +  GF  +A   F  LV 
Sbjct: 111 PRRDAGFSIFVFGINLGSIIAPWLVPWAAQGFGVHIFGSQLNFHAGFSLAAVGMFFGLVQ 170

Query: 234 FLVGTPKY 241
           +++G  KY
Sbjct: 171 YVLGGKKY 178


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.324    0.139    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,400,709
Number of Sequences: 164201
Number of extensions: 2835257
Number of successful extensions: 7385
Number of sequences better than 10.0: 33
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 7295
Number of HSP's gapped (non-prelim): 51
length of query: 583
length of database: 59,974,054
effective HSP length: 116
effective length of query: 467
effective length of database: 40,926,738
effective search space: 19112786646
effective search space used: 19112786646
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 69 (31.2 bits)