BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC146866.3 + phase: 0 
         (482 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

TT12_ARATH (Q9LYT3) TRANSPARENT TESTA 12 protein                      219  2e-56
YAO6_SCHPO (Q10085) Hypothetical protein C11D3.06 in chromosome I     200  6e-51
YD38_YEAST (Q05497) Hypothetical 77.8 kDa protein in MRPS28-HXT7...   157  4e-38
YHJ2_YEAST (P38767) Hypothetical 64.2 kDa protein in SLT2-PUT2 i...   132  3e-30
NORM_VIBPA (O82855) Multidrug resistance protein norM (Na(+)/dru...   110  1e-23
NORM_BACSU (O31855) Probable multidrug resistance protein norM (...   107  5e-23
NORM_VIBVU (Q8D9N8) Probable multidrug resistance protein norM (...   106  1e-22
NORM_BACHD (Q9KEJ2) Probable multidrug resistance protein norM (...   106  1e-22
NORM_HAEIN (P45272) Probable multidrug resistance protein norM (...   105  3e-22
NORM_VIBCH (Q9KRU4) Probable multidrug resistance protein norM (...   102  2e-21
NOM1_PSEAE (Q9I3Y3) Probable multidrug resistance protein norM 1...    94  6e-19
NORM_PASMU (Q9CMZ9) Probable multidrug resistance protein norM (...    91  5e-18
NORM_LISIN (Q92AG2) Probable multidrug resistance protein norM (...    91  9e-18
NORM_LISMO (Q8Y654) Probable multidrug resistance protein norM (...    89  3e-17
NOM2_PSEAE (Q9HTR0) Probable multidrug resistance protein norM 2...    87  1e-16
NORM_SYNY3 (Q55364) Probable multidrug resistance protein norM (...    85  5e-16
NORM_ECOLI (P37340) Multidrug resistance protein norM (Na(+)/dru...    83  1e-15
NORM_ECOL6 (Q8FH68) Multidrug resistance protein norM (Na(+)/dru...    83  1e-15
NORM_ECO57 (P58164) Multidrug resistance protein norM (Na(+)/dru...    83  1e-15
NORM_THEMA (Q9WZS2) Probable multidrug resistance protein norM (...    81  5e-15

>TT12_ARATH (Q9LYT3) TRANSPARENT TESTA 12 protein
          Length = 507

 Score =  219 bits (557), Expect = 2e-56
 Identities = 118/425 (27%), Positives = 226/425 (52%)

Query: 2   ISMIFLGYLGEMELAGGSLSIGFANITGYSVISGLAMGMEPICGQAYGAKQWKILGLTLQ 61
           ++++F G+LG ++LAG S++        Y ++ G+A  ++ +CGQAYGA+Q+  +G+  Q
Sbjct: 75  VTVMFTGHLGSLQLAGASIATVGIQGLAYGIMLGMASAVQTVCGQAYGARQYSSMGIICQ 134

Query: 62  RTVLLLLSTSIPISFIWINMKRILLFSGQDLEISSMAQSFILFLVPDLFLLSILHPLRIY 121
           R ++L L+ ++ ++F++     IL   GQ + I+   Q F   ++P ++  ++  P++ +
Sbjct: 135 RAMVLHLAAAVFLTFLYWYSGPILKTMGQSVAIAHEGQIFARGMIPQIYAFALACPMQRF 194

Query: 122 LRTQGITLPLTYCSAVSVLLHIPLNFLLVVHFQMGIAGVSIAMVLTNLNLVILLSSFLYF 181
           L+ Q I  PL Y S    LLH  L +L+      G+ G ++ +  +   LV +   ++  
Sbjct: 195 LQAQNIVNPLAYMSLGVFLLHTLLTWLVTNVLDFGLLGAALILSFSWWLLVAVNGMYILM 254

Query: 182 SSVYKKSWISPSLDCIKGWSSLLSLAIPTCVSVCLEWWWYEFMIMMCGLLVNPKATIASM 241
           S   K++W   S    +G      L + + V +CLE W+ + ++++ GLL NP  ++ ++
Sbjct: 255 SPNCKETWTGFSTRAFRGIWPYFKLTVASAVMLCLEIWYNQGLVIISGLLSNPTISLDAI 314

Query: 242 GILIQTTSLVYVFPSSLSLGVSTRIGNELGANRPQKARISMIVSLFLAMVLGLGAMLFTT 301
            I +   +    F   LS  +S R+ NELGA  P+ A +S++V     +++     +   
Sbjct: 315 SICMYYLNWDMQFMLGLSAAISVRVSNELGAGNPRVAMLSVVVVNITTVLISSVLCVIVL 374

Query: 302 LMRNQWGKFFTNDREILELTSIVLPIVGLCELGNCPQTTGCGVLRGSARPTIGANINLGS 361
           + R    K FT+D E++   S + P++ +    N  Q    GV  GS    + A +NL +
Sbjct: 375 VFRVGLSKAFTSDAEVIAAVSDLFPLLAVSIFLNGIQPILSGVAIGSGWQAVVAYVNLVT 434

Query: 362 FYLVGMPVAIFLGFVAKLGFPGLWIGLLAAQGSCAMLMLVVLCRTDWNLQVQRAKELTKS 421
           +Y++G+P+   LGF   LG  G+W G++A      + ++V+  +T+W  +V+ A +  K+
Sbjct: 435 YYVIGLPIGCVLGFKTSLGVAGIWWGMIAGVILQTLTLIVLTLKTNWTSEVENAAQRVKT 494

Query: 422 STTSD 426
           S T +
Sbjct: 495 SATEN 499


>YAO6_SCHPO (Q10085) Hypothetical protein C11D3.06 in chromosome I
          Length = 455

 Score =  200 bits (509), Expect = 6e-51
 Identities = 121/413 (29%), Positives = 217/413 (52%), Gaps = 4/413 (0%)

Query: 3   SMIFLGYLGEMELAGGSLSIGFANITGYSVISGLAMGMEPICGQAYGAKQWKILGLTLQR 62
           S+I  G LG  EL+  + +  FA  TG+ +  G     + +    +GA + + LG+ LQ 
Sbjct: 32  SVIVTGRLGPSELSVAAFAYMFAMSTGWLIALGGTTAFDTLGSNLWGAGKKQELGILLQT 91

Query: 63  TVLLLLSTSIPISFIWINMKRILLFSGQDLEISSMAQSFILFLVPDLFLLSILHPLRIYL 122
             ++L    +PI  +W   K IL+F  Q  E++  +Q F+ +L+P          L+ +L
Sbjct: 92  GFIVLSILYLPICLVWWYSKPILIFLHQTPELAEASQKFLRYLIPGGLGYVCFELLKKFL 151

Query: 123 RTQGITLPLTYCSAVSVLLHIPLNFLLVVHFQMGIAGVSIAMVLTNLNLVILLSSFLYFS 182
           +TQ IT   +Y   V+  L++ LNFLLV ++ +G+ G  +A  L+     ILL+ +  + 
Sbjct: 152 QTQEITRAGSYILLVTSPLNVALNFLLVHYYGLGLKGAPLATGLSYWLSFILLTQYAKYV 211

Query: 183 SVYKKSWISPSLDCIKGWSSLLSLAIPTCVSVCLEWWWYEFMIMMCGLLVNPKATIASMG 242
               ++W   +  C++ +   + L++   V V  EWW +E + ++ G L      +A+  
Sbjct: 212 KG-AEAWNGWNKRCLENFGPFVKLSLLGIVMVGTEWWAFEIVALVAGKL--GAVPLAAQS 268

Query: 243 ILIQTTSLVYVFPSSLSLGVSTRIGNELGANRPQKARISMIVSLFLAMVLGLGAMLFTTL 302
           +++ T  L+   P  L +  S R+   LGA  P  A ++  V+  + + +G   M+    
Sbjct: 269 VIMTTDQLLNTIPFGLGIITSNRVAYYLGAGLPDNASLTAKVAAIVGVAVGSVIMITMIA 328

Query: 303 MRNQWGKFFTNDREILELTSIVLPIVGLCELGNCPQTTGCGVLRGSARPTIGANINLGSF 362
           +RN +G+ FTND ++++L ++V+P+V   ++ +    T  G LRG+ R  +GA +N+ ++
Sbjct: 329 VRNIYGRIFTNDPDVIQLVALVMPLVAAFQISDSLNGTMGGALRGTGRQKVGAIVNITAY 388

Query: 363 YLVGMPVAIFLGFVAKLGFPGLWIGLLAAQGSCAMLMLVVLCRTDWNLQVQRA 415
           YL  +P+ I+L F  K G  GLWIG + A     +L L ++  TDW  Q ++A
Sbjct: 389 YLFALPLGIYLAFHGK-GLVGLWIGQVIALSIVGILELKIVMATDWISQSRKA 440


>YD38_YEAST (Q05497) Hypothetical 77.8 kDa protein in MRPS28-HXT7
           intergenic region
          Length = 695

 Score =  157 bits (398), Expect = 4e-38
 Identities = 115/433 (26%), Positives = 211/433 (48%), Gaps = 10/433 (2%)

Query: 1   MISMIFLGYLGEMELAGGSLSIGFANITGYSVISGLAMGMEPICGQAYGAKQWKILGLTL 60
           M+  + +G+LG+ ELA  SL+   +NIT  ++  G+A  ++ +C QAYG+ ++  +G+ L
Sbjct: 251 MVCSLTVGHLGKNELAAVSLASMTSNIT-LAIFEGIATSLDTLCPQAYGSGRFYSVGVHL 309

Query: 61  QRTVLLLLSTSIPISFIWINMKRILLFSGQDLEISSMAQSFILFLVPDLFLLSILHPLRI 120
           QR +   L   IP + +W   + +L +   + E+ ++   F+  L+           L+ 
Sbjct: 310 QRCIAFSLVIYIPFAVMWWYSEPLLSYIIPEKELINLTSRFLRVLILGAPAYIFFENLKR 369

Query: 121 YLRTQGITLPLTYCSAVSVLLHIPLNFLLVVHFQMGIA--GVSIAMVLTN-LNLVILLSS 177
           +L+ QGI     Y   +   L++ +++ LV +  +G+   G +IA+VL   L   +LL  
Sbjct: 370 FLQAQGIFDAGIYVLTICAPLNVLVSYTLVWNKYIGVGFIGAAIAVVLNFWLMFFLLLFY 429

Query: 178 FLYFSSVYKKSWISPSLDCIKGWSSLLSLAIPTCVSVCLEWWWYEFMIMMCGLLVNPKAT 237
            LY     +K W   S      W+ L  LA    + +  E   YE + +         + 
Sbjct: 430 ALYIDG--RKCWGGFSRKAFTHWNDLGHLAFSGIIMLEAEELSYELLTLFSAYY--GVSY 485

Query: 238 IASMGILIQTTSLVYVFPSSLSLGVSTRIGNELGANRPQKARISMIVSLFLAMVLGLGAM 297
           +A+   +    +L+Y+ P ++ +  STRI N +GA R   A IS  V L  + + G    
Sbjct: 486 LAAQSAVSTMAALLYMIPFAIGISTSTRIANFIGAKRTDFAHISSQVGLSFSFIAGFINC 545

Query: 298 LFTTLMRNQWGKFFTNDREILELTSIVLPIVGLCELGNCPQTTGCGVLRGSARPTIGANI 357
                 RN     ++ D E+++L + VLP+VG+ +  +         LRG    ++G+ +
Sbjct: 546 CILVFGRNLIANIYSKDPEVIKLIAQVLPLVGIVQNFDSLNAVAGSCLRGQGMQSLGSIV 605

Query: 358 NLGSFYLVGMPVAIFLGFVAKLGFPGLWIGLLAAQGSCAMLMLVVLCRTDWNLQVQRAKE 417
           NL ++YL G+P+A+ L +   +   GLWIG+ +A     ++    +   DW+ ++    E
Sbjct: 606 NLMAYYLFGIPLALILSWFFDMKLYGLWIGIGSAMLLIGLVEAYYVLFPDWD-KIMTYAE 664

Query: 418 LTKSSTTSDDVDA 430
           + K  T  D+VD+
Sbjct: 665 ILK-ETEDDEVDS 676


>YHJ2_YEAST (P38767) Hypothetical 64.2 kDa protein in SLT2-PUT2
           intergenic region
          Length = 581

 Score =  132 bits (331), Expect = 3e-30
 Identities = 98/364 (26%), Positives = 175/364 (47%), Gaps = 22/364 (6%)

Query: 1   MISMIFLGYLGEMELAGGSLSIGFANITGYSVISGLAMGMEPICGQAYGAKQWKILGLTL 60
           + S+  + +LG  EL G +L    ANITG + I GL   ++ +C QAYGAK + ++G+ +
Sbjct: 187 LASIFSVSHLGTKELGGVTLGSMTANITGLAAIQGLCTCLDTLCAQAYGAKNYHLVGVLV 246

Query: 61  QRTVLLLLSTSIPISFIW-INMKRILLFSGQDLEISSMAQSFI---LFLVPDLFLLSILH 116
           QR  ++ +   +P+ ++W +  ++IL     + E+ ++A +++    F VP   L     
Sbjct: 247 QRCAVITILAFLPMMYVWFVWSEKILALMIPERELCALAANYLRVTAFGVPGFILFEC-- 304

Query: 117 PLRIYLRTQGITLPLTYCSAVSVLLHIPLNFLLVVHFQMGIA--GVSIAMVLTNLNLVIL 174
             + +L+ QGI    T    V   L+  +N+LLV + ++GI   G  +++V   +N  ++
Sbjct: 305 -GKRFLQCQGIFHASTIVLFVCAPLNALMNYLLVWNDKIGIGYLGAPLSVV---INYWLM 360

Query: 175 LSSFLYFSSVYK------KSW--ISPSLDCIKGWSSLLSLAIPTCVSVCLEWWWYEFMIM 226
               L ++   K      K W  I P     K W  +++LAIP  V V  E+  +E + +
Sbjct: 361 TLGLLIYAMTTKHKERPLKCWNGIIPKEQAFKNWRKMINLAIPGVVMVEAEFLGFEVLTI 420

Query: 227 MCGLLVNPKATIASMGILIQTTSLVYVFPSSLSLGVSTRIGNELGANRPQKARISMIVSL 286
               L      + +  I+    SL Y  P S+S+  STR+ N +GA+      I+  VSL
Sbjct: 421 FASHLGTD--ALGAQSIVATIASLAYQVPFSISVSTSTRVANFIGASLYDSCMITCRVSL 478

Query: 287 FLAMVLGLGAMLFTTLMRNQWGKFFTNDREILELTSIVLPIVGLCELGNCPQTTGCGVLR 346
            L+ V     M      + Q    F+ +  ++++    LP++   +L +    +  G LR
Sbjct: 479 LLSFVCSSMNMFVICRYKEQIASLFSTESAVVKMVVDTLPLLAFMQLFDAFNASTAGCLR 538

Query: 347 GSAR 350
           G  R
Sbjct: 539 GQGR 542


>NORM_VIBPA (O82855) Multidrug resistance protein norM (Na(+)/drug
           antiporter) (Multidrug-efflux transporter)
          Length = 456

 Score =  110 bits (274), Expect = 1e-23
 Identities = 94/392 (23%), Positives = 168/392 (41%), Gaps = 38/392 (9%)

Query: 35  GLAMGMEPICGQAYGAKQWKILGLTLQRTVLLLLSTSIPISFIWINMKRILLFSGQDLEI 94
           GL M + P+  Q  G+ + + +   +Q+ V+L L  SIPI  + +  + IL     +  +
Sbjct: 63  GLLMALVPVVAQLNGSARREKIPFEIQQGVVLALLISIPIIGVLLQTQFILQLMDVEAVM 122

Query: 95  SSMAQSFI---LFLVPDLFLLSILHPLRIYLRTQGITLPLTYCSAVSVLLHIPLNFLLVV 151
           +     +I   +F VP   L   L   R +     +T P      + +LL+IPLN++ V 
Sbjct: 123 AGKTVGYIHAVIFAVPAFLLFQTL---RSFTDGMSLTKPAMVIGFIGLLLNIPLNWIFVY 179

Query: 152 HF----QMGIAGVSIAMVLTNLNLVILLSSFLYFSS----------VYKKSWISPSLDCI 197
                 ++G  G  +A  +    +  LL +++  SS           +K  W        
Sbjct: 180 GKFGAPELGGVGCGVATTIVYWVMFALLLAYVMTSSRLKSINVFGEYHKPQW-------- 231

Query: 198 KGWSSLLSLAIPTCVSVCLEWWWYEFMIMMCGLLVNPKATI--ASMGILIQTTSLVYVFP 255
           K    L  L  P   ++  E      +  +  LLV+P   I  A+  + I  +SLV++ P
Sbjct: 232 KAQVRLFKLGFPVAAALFFE----VTLFAVVALLVSPLGPIIVAAHQVAINFSSLVFMLP 287

Query: 256 SSLSLGVSTRIGNELGANRPQKARISMIVSLFLAMVLGLGAMLFTTLMRNQWGKFFTNDR 315
            S+   VS R+G+ LG      AR++  V + + + L     + T L R    + +TN+ 
Sbjct: 288 MSVGAAVSIRVGHRLGEENVDGARVASRVGIMVGLALATITAIITVLSRELIAELYTNNP 347

Query: 316 EILELTSIVLPIVGLCELGNCPQTTGCGVLRGSARPTIGANINLGSFYLVGMPVAIFLG- 374
           E++ L   +L    + +  +  Q    G LRG        N    +++++G+P    LG 
Sbjct: 348 EVISLAMQLLLFAAVYQCTDAVQVIAAGALRGYKDMRAIFNRTFIAYWILGLPTGYILGR 407

Query: 375 ---FVAKLGFPGLWIGLLAAQGSCAMLMLVVL 403
               V  +G  G W+G +    + A+++ V L
Sbjct: 408 TDWIVEPMGAQGFWLGFIIGLTAAALMLGVRL 439


>NORM_BACSU (O31855) Probable multidrug resistance protein norM
           (Na(+)/drug antiporter) (Multidrug-efflux transporter)
          Length = 452

 Score =  107 bits (268), Expect = 5e-23
 Identities = 104/416 (25%), Positives = 185/416 (44%), Gaps = 36/416 (8%)

Query: 2   ISMIFLGYLGEMELAGGSLSIGFANITG-YSVISGLAMGMEPICGQAYGAKQWKILGLTL 60
           +  +  G +   +LAG  ++IG +  T  Y+ ++G+ M + PI  Q  GA++ + +  T+
Sbjct: 34  LDTVMSGKVSPADLAG--VAIGSSLWTPVYTGLAGILMAVTPIVAQLLGAEKKQKIPFTV 91

Query: 61  QRTVLLLLSTSIPISFI-WINMKRILLFSGQDLEISSMAQSFILFLVPDLFLLSILHPLR 119
            + V +    SI +  I +  +  IL     D+ +  +A+ F+ FL   +F L +   LR
Sbjct: 92  LQAVYVAALLSIAVLVIGYAAVDLILGRLNLDIHVHQIAKHFLGFLSLGIFPLFVYTVLR 151

Query: 120 IYLRTQGITLPLTYCSAVSVLLHIPLNFLLVVHF--------QMGIAGVSIAMVLTNLNL 171
            ++ + G     T  + +  L  +P+NF+L   F         +G  G  +A  LT   +
Sbjct: 152 SFIDSLG----KTRVTMMITLSSLPINFVLNYVFIFGKFGMPALGGVGAGLASALTYWCI 207

Query: 172 VIL----------LSSFLYFSSVYKKSWISPSLDCIKGWSSLLSLAIPTCVSVCLEWWWY 221
            I+           S +  F ++YK SW        K   +LL + +P   +V  E   +
Sbjct: 208 CIISFFIIHKNAPFSEYGIFLTMYKFSW--------KACKNLLKIGLPIGFAVFFETSIF 259

Query: 222 EFMIMMCGLLVNPKATIASMGILIQTTSLVYVFPSSLSLGVSTRIGNELGANRPQKARIS 281
             + ++         TIAS    +   SL+Y+ P S+S+ ++  +G E GA R + AR  
Sbjct: 260 AAVTLLMSHFHT--VTIASHQAAMNFASLLYMLPLSVSMALTIVVGFEAGAARFKDARSY 317

Query: 282 MIVSLFLAMVLGLGAMLFTTLMRNQWGKFFTNDREILELTSIVLPIVGLCELGNCPQTTG 341
            ++ + +A+   L       L R Q    +T+D ++L LT   L      +L +      
Sbjct: 318 SLIGIMMAIGFSLFTAACILLFREQIAGMYTSDPDVLRLTQHFLIYALFFQLSDAVAAPI 377

Query: 342 CGVLRGSARPTIGANINLGSFYLVGMPVAIFLGFVAKLGFPGLWIGLLAAQGSCAM 397
            G LRG             S++++G+PV   +G    LG  G WIGL+A   + A+
Sbjct: 378 QGALRGYKDVNYTLAAAFVSYWVIGLPVGYMVGTFTSLGAFGYWIGLIAGLAAGAV 433


>NORM_VIBVU (Q8D9N8) Probable multidrug resistance protein norM
           (Na(+)/drug antiporter) (Multidrug-efflux transporter)
          Length = 483

 Score =  106 bits (265), Expect = 1e-22
 Identities = 94/390 (24%), Positives = 171/390 (43%), Gaps = 34/390 (8%)

Query: 35  GLAMGMEPICGQAYGAKQWKILGLTLQRTVLLLLSTSIPISFIWINMKRILLFSGQDLEI 94
           GL M + P+  Q  GA + + +   +Q+  ++ L  SIPI  +    + IL +   D  +
Sbjct: 90  GLLMALVPVVAQLNGAGKREQVPFEIQQGAVMALLISIPIIGVLFQTQWILGYMNVDAVM 149

Query: 95  SSMAQSFI---LFLVPDLFLLSILHPLRIYLRTQGITL--PLTYCSAVSVLLHIPLNFLL 149
           ++    +I   +F VP   L   L  L     T G++L  P      + +LL+IPLN++ 
Sbjct: 150 ATKTIGYIHAVMFAVPAFLLFQTLRSL-----TDGLSLTKPAMVIGFIGLLLNIPLNWMF 204

Query: 150 VVHFQMG---IAGVSIAMVLTNLNLVILLSSFLYFSSVYKKSWIS-------PSLDCIKG 199
           V + ++G   + GV   +    +  ++ L    Y ++ ++   +        P L+    
Sbjct: 205 V-YGKLGAPALGGVGCGVATAIVYWIMFLLLLFYVTTSHRLRQVQLFTTFHPPQLNA--- 260

Query: 200 WSSLLSLAIPTCVSVCLEWWWYEFMIMMCGLLVNP--KATIASMGILIQTTSLVYVFPSS 257
              L  L  P   ++  E      +  +  LLV P     +A+  + I  +SLV++ P S
Sbjct: 261 QVKLFKLGFPVAAALFFE----VTLFAVVALLVAPLGSTVVAAHQVAINFSSLVFMLPMS 316

Query: 258 LSLGVSTRIGNELGANRPQKARISMIVSLFLAMVLGLGAMLFTTLMRNQWGKFFTNDREI 317
           +    S R+G+ LG    + ARI+  V + + +   +   L T ++R Q    +T++R +
Sbjct: 317 IGAATSIRVGHMLGEKSTEGARIASHVGILVGLSTAVFTALLTVILREQIALLYTDNRVV 376

Query: 318 LELTSIVLPIVGLCELGNCPQTTGCGVLRGSARPTIGANINLGSFYLVGMPVAIFLG--- 374
           + L   +L    + +  +  Q    G LRG        N    +++L+G+P    LG   
Sbjct: 377 ITLAMQLLIFTAIYQCTDAIQVIAAGALRGYKDMRAIFNRTFIAYWLLGLPTGYVLGLTD 436

Query: 375 -FVAKLGFPGLWIGLLAAQGSCAMLMLVVL 403
             V  +G  G WIG +    S A ++ V L
Sbjct: 437 WIVEPMGAQGFWIGFIVGLSSAAAMLGVRL 466


>NORM_BACHD (Q9KEJ2) Probable multidrug resistance protein norM
           (Na(+)/drug antiporter) (Multidrug-efflux transporter)
          Length = 458

 Score =  106 bits (265), Expect = 1e-22
 Identities = 98/426 (23%), Positives = 193/426 (45%), Gaps = 28/426 (6%)

Query: 5   IFLGYLGEMELAGGSLSIGFANITGYSVISGLAMGMEPICGQAYGAKQWKILGLTLQRTV 64
           +  G  G  +LAG ++      +  ++ ++G+ + + PI  Q+ GA++   +     + +
Sbjct: 37  VMSGQAGANDLAGVAIGSSLW-VPVFTGLNGVLLALTPIIAQSIGAEKRDDVPYVFLQGL 95

Query: 65  LLLLSTSIPISFIW-INMKRILLFSGQDLEISSMAQSFILFLVPDLFLLSILHPLRIYLR 123
            L ++ SI +  I  + +  IL     + E+  +A+ +++ L   +  L I   +R  + 
Sbjct: 96  YLSIAISIAVILIGAVVLDPILSAMSLEDEVGRIAKEYLIGLAFGIVPLFIYTTIRCLID 155

Query: 124 TQGITLPLTYCSAVSVLLHIPLNFLLVVHF----QMGIAGVSIAMVLTN-------LNLV 172
           + G T    + + +S+ ++I  N++L+       ++G  G   A  +T        + +V
Sbjct: 156 SLGETRVTMFITLLSLPINIFFNYVLIFGKLGFPRLGGVGAGYASAITYWFILAVAIVVV 215

Query: 173 ILLSSFLYFSSVYKKSWISPSLDCIKGWSSLLSLAIPTCVSVCLEWWWYEFMIMMCGLLV 232
           + +  F  F    K   +S     +K W  +L L +P   ++  E   +  + ++     
Sbjct: 216 VKVRPFTDFQLFKKLYHVS-----LKKWKEILLLGLPIGFTIFFETSIFAAVTLLMSTF- 269

Query: 233 NPKATIASMGILIQTTSLVYVFPSSLSLGVSTRIGNELGANRPQKARISMIVSLFLAMVL 292
              ATIA+    +   S +Y+ P S++  ++  +G E+GA R + AR    + +  A+++
Sbjct: 270 -DTATIAAHQAAVNFASFLYMIPLSIAFTLTIAVGYEVGAKRVEDARQYSRLGITFALIM 328

Query: 293 GLGAMLFTTLMRNQWGKFFTNDREILELTSIVLPIVGLCELGNCPQTTGCGVLRGSARPT 352
           GL A +   ++R      +TND ++  L    L      +L +   T   GVLRG     
Sbjct: 329 GLVAGVIIYVLRAPVASLYTNDSQVAWLIQQFLIYSIFFQLSDALATPIQGVLRGHKDVN 388

Query: 353 IGANINLGSFYLVGMPVAIFLGFVAKLGFPGLWIGLLAAQGSCAMLMLVVLCRTDWNL-Q 411
           +   + L SF+++G+P    L   + LG  G WIGL+    SCA+ +        W L Q
Sbjct: 389 VPFVMALVSFWIIGLPTGYLLANFSPLGPYGYWIGLITGLASCAIAL-------SWRLKQ 441

Query: 412 VQRAKE 417
           +QR  E
Sbjct: 442 MQRKFE 447


>NORM_HAEIN (P45272) Probable multidrug resistance protein norM
           (Na(+)/drug antiporter) (Multidrug-efflux transporter)
          Length = 464

 Score =  105 bits (261), Expect = 3e-22
 Identities = 84/376 (22%), Positives = 166/376 (43%), Gaps = 13/376 (3%)

Query: 35  GLAMGMEPICGQAYGAKQWKILGLTLQRTVLLLLSTSIPISFIWINMKRILLFSGQDLEI 94
           GL + + P      G+ Q   +   +++ + L+L  SIP+  +    +  L +   + ++
Sbjct: 68  GLLLALPPTISYLNGSGQHHRIAHQVRQGIWLVLGVSIPLGLLIYFCEIPLQYMQMESKM 127

Query: 95  SSMAQSFILFLVPDLFLLSILHPLRIYLRTQGITLPLTYCSAVSVLLHIPLNFLLVV-HF 153
           S +A+ ++  ++  L    +L   R        T P    + + +L++IPLN++ +   F
Sbjct: 128 SDLARDYLHAMLWGLPAYLMLINFRCLNDGIEKTKPAMVITFLGLLINIPLNYIFIYGKF 187

Query: 154 QM---GIAGVSIAMVLTNLNLVILLSSFLYFSSVYKKSWISPSLDCI---KGWSSLLSLA 207
            M   G  G  IA  + N  + +++  + Y ++  +   +   L  +   K    LL L 
Sbjct: 188 GMPAFGAVGCGIATAIVNWAMCLMMIFYSYTNTQERSLKVFSQLIEMPNPKTLKKLLRLG 247

Query: 208 IPTCVSVCLEWWWYEFMIMMCGLLVNPKATIASMGILIQTTSLVYVFPSSLSLGVSTRIG 267
           +P  +++C E   Y    +M   L      +AS  I + T+S +++FP S+ +  +  +G
Sbjct: 248 LPIAIAICCEVALYALTSLMLSPL--GATIVASHQITLNTSSFIFMFPMSIGMATTILVG 305

Query: 268 NELGANRPQKARISMIVSLFLAMVLGLGAMLFTTLMRNQWGKFFTNDREILELTSIVLPI 327
             LGA  PQ A+     +L L + + +   L T   R +    F  D  ++ + + +L  
Sbjct: 306 QALGAGSPQNAKKIGYAALLLGLTVTIVTALITIFFRYEIASIFVTDEIVIAMAANLLLF 365

Query: 328 VGLCELGNCPQTTGCGVLRGSARPTIGANINLGSFYLVGMPVAIFLG----FVAKLGFPG 383
             L +  +  Q    G+LRG     +   I L S++++G+P+   LG     V  +   G
Sbjct: 366 AALYQFSDTIQMVVGGILRGYKDTKVILYITLFSYWVIGVPLGYTLGRTDWLVPHIDAKG 425

Query: 384 LWIGLLAAQGSCAMLM 399
            WI  + +    A L+
Sbjct: 426 FWIAFVVSLTFAAFLL 441


>NORM_VIBCH (Q9KRU4) Probable multidrug resistance protein norM
           (Na(+)/drug antiporter) (Multidrug-efflux transporter)
          Length = 461

 Score =  102 bits (254), Expect = 2e-21
 Identities = 94/416 (22%), Positives = 181/416 (42%), Gaps = 28/416 (6%)

Query: 2   ISMIFLGYLGEMELAGGSLSIGFANITGYSVISG--LAMGMEPICGQAYGAKQWKILGLT 59
           +  I  G +  +++A  S++   A+I   S++ G  L M + P+  Q  GA +   +   
Sbjct: 35  VDTIMAGGVSAIDMAAVSIA---ASIWLPSILFGVGLLMALVPVVAQLNGAGRQHKIPFE 91

Query: 60  LQRTVLLLLSTSIPISFIWINMKRILLFSGQDLEISSMAQSF---ILFLVPDLFLLSILH 116
           + + ++L L  S+PI  +    + I+ F   +  +++    +   ++F VP   L   L 
Sbjct: 92  VHQGLILALLVSVPIIAVLFQTQFIIRFMDVEEAMATKTVGYMHAVIFAVPAYLLFQAL- 150

Query: 117 PLRIYLRTQGITLPLTYCSAVSVLLHIPLNFLLVVHF----QMGIAGVSIAMVLTNLNLV 172
             R +     +T P      + +LL+IPLN++ V       ++G  G  +A  +    ++
Sbjct: 151 --RSFTDGMSLTKPAMVIGFIGLLLNIPLNWIFVYGKFGAPELGGVGCGVATAIVYWIML 208

Query: 173 ILLSSFLYFSS--VYKKSWISPSLDCIKGWSSLLSLAIPTCVSVCLEWWWYEFMIMMCGL 230
           +LL  ++  S    + K + +      K    L  L  P   ++  E      +  +  L
Sbjct: 209 LLLLFYIVTSKRLAHVKVFETFHKPQPKELIRLFRLGFPVAAALFFE----VTLFAVVAL 264

Query: 231 LVNP--KATIASMGILIQTTSLVYVFPSSLSLGVSTRIGNELGANRPQKARISMIVSLFL 288
           LV P     +A+  + +  +SLV++FP S+   VS R+G++LG    + A I+  V L  
Sbjct: 265 LVAPLGSTVVAAHQVALNFSSLVFMFPMSIGAAVSIRVGHKLGEQDTKGAAIAANVGLMT 324

Query: 289 AMVLGLGAMLFTTLMRNQWGKFFTNDREILELTSIVLPIVGLCELGNCPQTTGCGVLRGS 348
            +       L T L R Q    +T ++ ++ L   +L    + +  +  Q    G LRG 
Sbjct: 325 GLATACITALLTVLFREQIALLYTENQVVVALAMQLLLFAAIYQCMDAVQVVAAGSLRGY 384

Query: 349 ARPTIGANINLGSFYLVGMPVAIFLGFV-----AKLGFPGLWIGLLAAQGSCAMLM 399
              T   +    S++++G+P    LG         LG  G W+G +    + A+++
Sbjct: 385 KDMTAIFHRTFISYWVLGLPTGYILGMTNWLTEQPLGAKGFWLGFIIGLSAAALML 440


>NOM1_PSEAE (Q9I3Y3) Probable multidrug resistance protein norM 1
           (Na(+)/drug antiporter) (Multidrug-efflux transporter)
          Length = 477

 Score = 94.4 bits (233), Expect = 6e-19
 Identities = 76/307 (24%), Positives = 140/307 (44%), Gaps = 18/307 (5%)

Query: 113 SILHPLRIYLRTQGITLPLTYCSAVSVLLHIPLNFLLVV-HFQMGIAGVSIAMVLTNLNL 171
           ++ H LR Y    G T P        +LL+IP+N+ L+  HF M   G       T   +
Sbjct: 152 ALYHVLRCYTNGLGRTRPSMVLGIGGLLLNIPINYALIYGHFGMPKMGGPGCGWATGSVM 211

Query: 172 VILLSSFLYF---SSVYKKS-----WISPSLDCIKGWSSLLSLAIPTCVSVCLEWWWYEF 223
             +    L++   +S+Y+ S     W  P    I     L+++ +P  ++V  E   +  
Sbjct: 212 WFMFLGMLFWVNKASIYRASQLFSRWEWPDRATI---GPLVAVGLPIGIAVFAESSIFSV 268

Query: 224 MIMMCGLLVNPKATIASMGILIQTTSLVYVFPSSLSLGVSTRIGNELGANRPQKARISMI 283
           + ++ G L   +  +A   I +  ++LV++ P SL + V+ R+G+ LGA  P+ AR +  
Sbjct: 269 IALLIGGL--DENVVAGHQIALNFSALVFMIPYSLGMAVTVRVGHNLGAGLPRDARFAAG 326

Query: 284 VSLFLAMVLGLGAMLFTTLMRNQWGKFFTNDREILELTSIVLPIVGLCELGNCPQTTGCG 343
           V +  A+     +     L+R Q    ++ D  ++ + + ++    L +  +  Q T  G
Sbjct: 327 VGMAAALGYACVSASLMLLLREQIAAMYSPDPAVIAIAASLIVFSALFQFSDALQVTAAG 386

Query: 344 VLRGSARPTIGANINLGSFYLVGMPVAIFLG----FVAKLGFPGLWIGLLAAQGSCAMLM 399
            LRG     +   + L +++ +G+PV   LG    F    G  GLW GL+      A+++
Sbjct: 387 ALRGYQDTRVTMIMTLFAYWGIGLPVGYSLGLTDWFQEPTGPRGLWQGLVVGLTGAAIML 446

Query: 400 LVVLCRT 406
            + L R+
Sbjct: 447 CIRLARS 453


>NORM_PASMU (Q9CMZ9) Probable multidrug resistance protein norM
           (Na(+)/drug antiporter) (Multidrug-efflux transporter)
          Length = 464

 Score = 91.3 bits (225), Expect = 5e-18
 Identities = 79/384 (20%), Positives = 167/384 (42%), Gaps = 25/384 (6%)

Query: 35  GLAMGMEPICGQAYGAKQWKILGLTLQRTVLLLLSTSIPISFIWINMKRILLFSGQDLEI 94
           GL + + P      G+ +   +   +++ + ++L + +P+  +      +  +   +  +
Sbjct: 68  GLLLALPPTISYLNGSGKRDQIAHQVRQGIWIILFSCLPLGILIYYSNLVFDYMQVEDHL 127

Query: 95  SSMAQSFILFLVPDLFLLSILHPLRIYLRTQGITLPLTYCSAVSVLLHIPLNFLLVVHFQ 154
             +   ++  ++  L    ++   R        T P    + + + L+IPLN++ + + +
Sbjct: 128 KEITIGYLHAMIWGLPAYLLMINFRCLNDGIAKTKPAMVITFLGLGLNIPLNYIFI-YGK 186

Query: 155 MGI-----AGVSIAMVLTNLNLVILLSSFLYFS------SVYKKSWISPSLDCIKGWSSL 203
           +GI      G  IA  + N  + IL+ ++   +       V+ K    P+   +K    L
Sbjct: 187 LGIPAFGAVGCGIATAIVNWFMCILMIAYCKNARNQRDLKVFAKILEKPNFTTLK---KL 243

Query: 204 LSLAIPTCVSVCLEWWWYEFMIMMCGLLVNPKAT--IASMGILIQTTSLVYVFPSSLSLG 261
           L+L  P  V++  E      +  +  LL++P  T  +AS  I + T+S +++ P SL + 
Sbjct: 244 LNLGFPIAVALFCE----VALFALTALLLSPLGTDIVASHQIALNTSSFLFMLPMSLGMA 299

Query: 262 VSTRIGNELGANRPQKARISMIVSLFLAMVLGLGAMLFTTLMRNQWGKFFTNDREILELT 321
            +  +G  LG     KA+     +L + +++ +     T + R +  + F  DR+++ + 
Sbjct: 300 ATILVGQRLGEGAADKAKQVSYSALIVGLLIAVITATLTVIFRVEIAEIFVKDRDVIAMA 359

Query: 322 SIVLPIVGLCELGNCPQTTGCGVLRGSARPTIGANINLGSFYLVGMPVAIFLG----FVA 377
             +L I  L +  +  Q    G LRG         I L  +++VGMP+   L      + 
Sbjct: 360 GTLLLIAALYQFSDTVQVVAGGALRGYKDTKAILYITLFCYWVVGMPMGYTLARTDLLMP 419

Query: 378 KLGFPGLWIGLLAAQGSCAMLMLV 401
            LG  G WIG + +    A L+++
Sbjct: 420 ALGAEGFWIGFVVSLTIAATLLMI 443


>NORM_LISIN (Q92AG2) Probable multidrug resistance protein norM
           (Na(+)/drug antiporter) (Multidrug-efflux transporter)
          Length = 456

 Score = 90.5 bits (223), Expect = 9e-18
 Identities = 98/394 (24%), Positives = 180/394 (44%), Gaps = 20/394 (5%)

Query: 31  SVISGLAMGMEPICGQAYGAKQWKILGLTLQRTVLLLLSTSIPISFI-WINMKRILLFSG 89
           +  SGL M + PI  Q  GAK+ K +  T+   + + L  +  +  I ++ +  IL    
Sbjct: 62  AAFSGLLMAITPIIAQLIGAKKEKQVKNTVHNGLYIALFLAFILILINFLVVPTILTHMP 121

Query: 90  QDLEISSMAQSF---ILFLVPDLFLLSILHPLRIYLRTQGITLPLTYCSAVSVLLHIPLN 146
              E++ +A+ F   I   +P  F+ +IL      L    +T+ +T C+   V  +I LN
Sbjct: 122 VTAEVAHIARHFLNGICIGIPAFFISAILRSFIDSLGLTRVTMLITLCT---VPFNIFLN 178

Query: 147 FLLVV-HF---QMGIAGVSIAMVLTNLNLVILLSSFLYFSSVYKKSWISPSLDCIK--GW 200
           +  +  +F   +MG AG   A  +T   +V++    +   +  +K  I   L  ++    
Sbjct: 179 YCFIFGNFGFPEMGGAGSGYATGITYWLVVLVSVILIQTQTRLRKFGIFKGLTALRFSKV 238

Query: 201 SSLLSLAIPTCVSVCLEWWWYEFMIMMCGLLVNPKATIASMGILIQTTSLVYVFPSSLSL 260
             ++ + +P  +++  E   +  + ++ G       TIA+        +L+Y FP S++ 
Sbjct: 239 KEIIGIGVPNGLTILFETSIFSAVTILMGAFGTE--TIAAHQSANSVCTLLYAFPLSVAS 296

Query: 261 GVSTRIGNELGANRPQKARISMIVSLFLAMVLGL--GAMLFTTLMRNQWGKFFTNDREIL 318
            ++   G E GA R + A+    + +  A+++G   GA+LF    R+    F+TND E+ 
Sbjct: 297 TLTILGGYETGAKRLKDAKQYRHIGMTAAILIGCINGAILF--FFRDIIAGFYTNDAELS 354

Query: 319 ELTSIVLPIVGLCELGNCPQTTGCGVLRGSARPTIGANINLGSFYLVGMPVAIFLGFVAK 378
           +L    L    L +  +   +   G LRG     I + I   S++L+G+PV   L F   
Sbjct: 355 DLIMHFLVYAILFQFADAVLSPVLGALRGYKDVAITSIIAFISYWLIGLPVGYGLSF-TN 413

Query: 379 LGFPGLWIGLLAAQGSCAMLMLVVLCRTDWNLQV 412
           LG  G WIGL       A ++ + + +T+  L +
Sbjct: 414 LGPFGYWIGLSTGLFVAAFILSIRVRKTERKLSL 447


>NORM_LISMO (Q8Y654) Probable multidrug resistance protein norM
           (Na(+)/drug antiporter) (Multidrug-efflux transporter)
          Length = 456

 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 98/394 (24%), Positives = 180/394 (44%), Gaps = 24/394 (6%)

Query: 31  SVISGLAMGMEPICGQAYGAKQWKILGLTLQRTVLLLLSTS---IPISFIWINMKRILLF 87
           +  SGL M + PI  Q  GAK+ K +  T+   + + L  +   I I+F+ + M  IL  
Sbjct: 62  AAFSGLLMAITPIIAQLIGAKKEKQVKNTVHNGLYIALFLAFILILINFLVVPM--ILTH 119

Query: 88  SGQDLEISSMAQSF---ILFLVPDLFLLSILHPLRIYLRTQGITLPLTYCSAVSVLLHIP 144
                E++ +A+ F   I   +P  F+ +IL      L    +T+ +T C+   V  +I 
Sbjct: 120 MPVTAEVADIARHFLNGICIGIPAFFISAILRSFIDSLGLTRVTMLITLCT---VPFNIF 176

Query: 145 LNFLLVV-HF---QMGIAGVSIAMVLTNLNLVILLSSFLYFSSVYKKSWISPSLDCIK-- 198
           LN+  +  +F   +MG AG   A  +T   +V++    +   +  +K  +   L  ++  
Sbjct: 177 LNYCFIFGNFGFPEMGGAGSGYATGITYWLVVLVSVILIQTQTRLRKFGVFKGLTALRFS 236

Query: 199 GWSSLLSLAIPTCVSVCLEWWWYEFMIMMCGLLVNPKATIASMGILIQTTSLVYVFPSSL 258
               ++ + +P  +++  E   +  + ++ G       TIA+        +L+Y FP S+
Sbjct: 237 KIKEIIGIGVPNGLTILFETSIFSAVTILMGAFGTE--TIAAHQSANSVCTLLYAFPLSV 294

Query: 259 SLGVSTRIGNELGANRPQKARISMIVSLFLAMVLGL--GAMLFTTLMRNQWGKFFTNDRE 316
           +  ++   G E GA R + A+    + +  A+++G   GA+LF    R+    F+TND  
Sbjct: 295 ASTLTILGGYETGAKRLKDAKQYRHIGMAAAILIGCVNGAILF--FFRDIIAGFYTNDPA 352

Query: 317 ILELTSIVLPIVGLCELGNCPQTTGCGVLRGSARPTIGANINLGSFYLVGMPVAIFLGFV 376
           +  L    L    L +  +   +   G LRG    T+ + +   S++L+G+PV   L F 
Sbjct: 353 LSNLIMHFLVYAILFQFADAVLSPVLGALRGYKDVTVTSIVAFISYWLIGLPVGYGLSF- 411

Query: 377 AKLGFPGLWIGLLAAQGSCAMLMLVVLCRTDWNL 410
             LG  G WIGL       A ++ + + +T+  L
Sbjct: 412 TNLGPFGYWIGLSTGLFVAAFILSIRVRKTEQKL 445


>NOM2_PSEAE (Q9HTR0) Probable multidrug resistance protein norM 2
           (Na(+)/drug antiporter) (Multidrug-efflux transporter)
          Length = 488

 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 101/421 (23%), Positives = 176/421 (40%), Gaps = 39/421 (9%)

Query: 5   IFLGYLGEMELAGGSL-SIGFANITGYSV--------ISGLAMGMEPICGQAYGAKQWKI 55
           + +G LG   LA G L ++ +A ++ + V        +  +  G +   G A  A+    
Sbjct: 35  VMMGKLGPDALAAGGLGAVSYAFVSTFCVGVVAAVGNLVAIRHGCDDAAGAAAAARSGLW 94

Query: 56  LGLTLQRTVLLLLSTSIPISFIWINMKRILLFSGQDLEISSMAQSFI---LFLVPDLFLL 112
           +G  L     LLL         W N++ +LL  GQ  +    A  F+    F +P     
Sbjct: 95  VGAALALAAGLLL---------W-NLRPLLLVFGQAPQTVDGAMQFLHSLTFALPGYMAF 144

Query: 113 SILHPLRIYLRTQGITLPLTYCSAVSVLLHIPLNFLLVVHF----QMGIAGVSIAMVLTN 168
            +L      +   G   P+   S +  L ++ LN+  +       ++G+AG+ +   L  
Sbjct: 145 MVLRGFTSAIDRAG---PVMAISVLGALANLALNYSFIEGLFGLPRLGLAGIGLVTALVM 201

Query: 169 LNLVILLSSFLYFSSVYKKSWISPSLDCIKGW--SSLLSLAIPTCVSVCLEWWWYEFMIM 226
             + +LL+ ++     Y +  +   L   +      +L L +P   +  +E   +    +
Sbjct: 202 NCMPLLLALYIRLQPAYAEYSLLRGLGRPQRAMVEEILRLGLPIGGTYAVESGMFTVATL 261

Query: 227 MCGLLVNPKATIASMGILIQTTSLVYVFPSSLSLGVSTRIGNELGANRPQKARISMIVSL 286
             G++ +    +A+  I IQ   + ++ P  LS   + RIG   GA R  +AR +  V +
Sbjct: 262 CMGIIGDH--ALAAHQIAIQAVYVAFMVPVGLSYATTYRIGQHFGAGRLLEARRAGRVGI 319

Query: 287 -FLAMVLGLGAMLFTTLMRNQWGKFFTND----REILELTSIVLPIVGLCELGNCPQTTG 341
            F A+ + L A LF  +     G F   D    RE+  +   +L I    EL +  Q   
Sbjct: 320 GFGALCMLLFAGLFWWMPEAIIGLFLDRDAPANREVAAMAVSLLAIAAWFELFDGTQNVA 379

Query: 342 CGVLRGSARPTIGANINLGSFYLVGMPVAIFLGFVAKLGFPGLWIGLLAAQGSCAMLMLV 401
            G +RG         + L  ++LVG+P+A  L F A  G  G+W G LA   +CA + L 
Sbjct: 380 MGAIRGLKDARTTFLVGLACYWLVGVPLACLLAFAAGWGAAGVWWG-LAGGLACAAIGLT 438

Query: 402 V 402
           +
Sbjct: 439 L 439


>NORM_SYNY3 (Q55364) Probable multidrug resistance protein norM
           (Na(+)/drug antiporter) (Multidrug-efflux transporter)
          Length = 461

 Score = 84.7 bits (208), Expect = 5e-16
 Identities = 92/401 (22%), Positives = 181/401 (44%), Gaps = 22/401 (5%)

Query: 2   ISMIFLGYLGEMELAGGSLS----IGFANITGYSVISGLAMGMEPICGQAYGAKQWKILG 57
           +  + +G+LG+  LA G L+    + F  +TG  +ISG++    P+  +AYGA Q + +G
Sbjct: 37  VDTVMMGWLGQDVLAAGGLATMIFMAFM-MTGVGLISGVS----PLVAEAYGAGQTRRIG 91

Query: 58  LTLQRTVLLLLSTSIPISFIWINMKRILLFSGQDLEISSMAQSFILFLVPDLFLLSILHP 117
              ++ + ++L  SIP      ++  ++ +SGQ      ++ S++  +   LF       
Sbjct: 92  QLTRQGLWIVLLLSIPGMLFITHLNGVMHWSGQADTTIILSDSYLNVMAWGLFPAIAFAT 151

Query: 118 LR----IYLRTQGITLPLTYCSAVSVLLHIPLNFLLVVHFQMGIAGVSIAMVLTNLNLVI 173
           LR       + + I L +   +  ++L +  L F       +GI G++IA +  +  + +
Sbjct: 152 LRGCIIALSQARPIMLIVIAATLFNILGNYGLGFGKWGFPALGITGLAIASISAHWIMFL 211

Query: 174 LLSSFLYFSSVYKKSWISPSLDCIKG--WSSLLSLAIPTCVSVCLEWWWYEFMIMMCGLL 231
            L  ++ +     +  +  SL  +K      LL +  P  ++  LE+  Y       G L
Sbjct: 212 SLLVYMLWHKPLHQYSLFDSLHHLKPRILQQLLWVGGPIGIAAVLEYGLYLTASFFMGAL 271

Query: 232 VNPKATIASMGILIQTTSLVYVFPSSLSLGVSTRIGNELGANRPQKARISMIVSLFLAMV 291
             P   +A+  ++ QT  ++++ P ++S   + R+G   G     + R + +VS+ LA++
Sbjct: 272 GTP--ILAAHQVVSQTVLVLFMVPLAMSYAATVRVGQWFGQQHWPQIRQAALVSIGLAVL 329

Query: 292 LGLGAMLFTTLMRNQWGKFF--TNDREILELTSIVLPIVGLCELG---NCPQTTGCGVLR 346
             L A +       Q    +   ND    E  ++ + I+ +   G   +  Q T  GVL+
Sbjct: 330 FMLTAGIALLAYPQQIIGLYLDLNDPANGEALNVGISIMKIAAFGLVLDGLQRTANGVLQ 389

Query: 347 GSARPTIGANINLGSFYLVGMPVAIFLGFVAKLGFPGLWIG 387
           G     I   +   +++ +G+  +  LGF   L   G+WIG
Sbjct: 390 GLQDTRIPMVLGTIAYWGIGLTASYLLGFYTPLSGAGVWIG 430


>NORM_ECOLI (P37340) Multidrug resistance protein norM (Na(+)/drug
           antiporter) (Multidrug-efflux transporter)
          Length = 457

 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 62/282 (21%), Positives = 126/282 (43%), Gaps = 8/282 (2%)

Query: 128 TLPLTYCSAVSVLLHIPLNFLLVV-HFQMG-IAGVSIAMVLTNLNLVILLSSFLYFSSVY 185
           T P      + +L++IP+N++ +  HF M  + GV   +    +  V+ L+   Y     
Sbjct: 157 TKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRAR 216

Query: 186 KKSWISPSLDCIKGWSSLLSLAIPTCVSVCLEWWWYEFMIMMCGLLVNPKATIASMG--I 243
               I       K   +++   I   + + L  ++   +  +  LLV+P   +   G  I
Sbjct: 217 SMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQI 276

Query: 244 LIQTTSLVYVFPSSLSLGVSTRIGNELGANRPQKARISMIVSLFLAMVLGLGAMLFTTLM 303
            +  +SL++V P SL+  V+ R+G  LG      A+ +    L + + +     +FT  +
Sbjct: 277 ALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSL 336

Query: 304 RNQWGKFFTNDREILELTSIVLPIVGLCELGNCPQTTGCGVLRGSARPTIGANINLGSFY 363
           R Q    + ++ E++ L + ++ +  + ++ +  Q  G G+LRG         I   +++
Sbjct: 337 REQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYW 396

Query: 364 LVGMPVAIFLGF----VAKLGFPGLWIGLLAAQGSCAMLMLV 401
           ++G+P    L      V  +G  G WIG +    S A++M++
Sbjct: 397 VLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMML 438


>NORM_ECOL6 (Q8FH68) Multidrug resistance protein norM (Na(+)/drug
           antiporter) (Multidrug-efflux transporter)
          Length = 457

 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 62/282 (21%), Positives = 126/282 (43%), Gaps = 8/282 (2%)

Query: 128 TLPLTYCSAVSVLLHIPLNFLLVV-HFQMG-IAGVSIAMVLTNLNLVILLSSFLYFSSVY 185
           T P      + +L++IP+N++ +  HF M  + GV   +    +  V+ L+   Y     
Sbjct: 157 TKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRAR 216

Query: 186 KKSWISPSLDCIKGWSSLLSLAIPTCVSVCLEWWWYEFMIMMCGLLVNPKATIASMG--I 243
               I       K   +++   I   + + L  ++   +  +  LLV+P   +   G  I
Sbjct: 217 SMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQI 276

Query: 244 LIQTTSLVYVFPSSLSLGVSTRIGNELGANRPQKARISMIVSLFLAMVLGLGAMLFTTLM 303
            +  +SL++V P SL+  V+ R+G  LG      A+ +    L + + +     +FT  +
Sbjct: 277 ALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSL 336

Query: 304 RNQWGKFFTNDREILELTSIVLPIVGLCELGNCPQTTGCGVLRGSARPTIGANINLGSFY 363
           R Q    + ++ E++ L + ++ +  + ++ +  Q  G G+LRG         I   +++
Sbjct: 337 REQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYW 396

Query: 364 LVGMPVAIFLGF----VAKLGFPGLWIGLLAAQGSCAMLMLV 401
           ++G+P    L      V  +G  G WIG +    S A++M++
Sbjct: 397 VLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMML 438


>NORM_ECO57 (P58164) Multidrug resistance protein norM (Na(+)/drug
           antiporter) (Multidrug-efflux transporter)
          Length = 457

 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 62/282 (21%), Positives = 126/282 (43%), Gaps = 8/282 (2%)

Query: 128 TLPLTYCSAVSVLLHIPLNFLLVV-HFQMG-IAGVSIAMVLTNLNLVILLSSFLYFSSVY 185
           T P      + +L++IP+N++ +  HF M  + GV   +    +  V+ L+   Y     
Sbjct: 157 TKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRAR 216

Query: 186 KKSWISPSLDCIKGWSSLLSLAIPTCVSVCLEWWWYEFMIMMCGLLVNPKATIASMG--I 243
               I       K   +++   I   + + L  ++   +  +  LLV+P   +   G  I
Sbjct: 217 SMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQI 276

Query: 244 LIQTTSLVYVFPSSLSLGVSTRIGNELGANRPQKARISMIVSLFLAMVLGLGAMLFTTLM 303
            +  +SL++V P SL+  V+ R+G  LG      A+ +    L + + +     +FT  +
Sbjct: 277 ALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSL 336

Query: 304 RNQWGKFFTNDREILELTSIVLPIVGLCELGNCPQTTGCGVLRGSARPTIGANINLGSFY 363
           R Q    + ++ E++ L + ++ +  + ++ +  Q  G G+LRG         I   +++
Sbjct: 337 REQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYW 396

Query: 364 LVGMPVAIFLGF----VAKLGFPGLWIGLLAAQGSCAMLMLV 401
           ++G+P    L      V  +G  G WIG +    S A++M++
Sbjct: 397 VLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMML 438


>NORM_THEMA (Q9WZS2) Probable multidrug resistance protein norM
           (Na(+)/drug antiporter) (Multidrug-efflux transporter)
          Length = 464

 Score = 81.3 bits (199), Expect = 5e-15
 Identities = 102/443 (23%), Positives = 186/443 (41%), Gaps = 45/443 (10%)

Query: 1   MISMIFLGYLGEMELAGGSLSIGFANITGYSVISGLAMGMEPICGQAYGAKQWKILGLTL 60
           M    FLG+     ++G  LS     +    +I+  +MG       A GA   K +    
Sbjct: 41  MADTAFLGHYSWKAMSGVGLSNQVFWVVQVVLIAA-SMGATVTIANAIGAGNRKAVRSLA 99

Query: 61  QRTVLLLLSTSI------PISFIWINMKRILLFSGQDLEISSMAQSFILFLVPDLFLLSI 114
             +V L + T +      P+S + IN     +F   + EI S A+ ++  ++      SI
Sbjct: 100 WNSVFLAIFTGVILTALTPLSDVLIN-----IFPNLEGEIESSAKEYLKVILSGSMGFSI 154

Query: 115 LHPLRIYLRTQGITLPLTYCSAVSVLLHIPLNFLLVVHF----QMGIAGVSIAMVLTNLN 170
           +      LR  G T      + ++  L+I L++ ++       +MG+ G ++A +L+   
Sbjct: 155 MAVFSAMLRGAGDTRTPMIVTGLTNFLNIFLDYAMIFGKFGFPEMGVRGAAVATILSRFV 214

Query: 171 LVILLSSFLYFSSVY--KKSWISPSLDCIKGWSS---LLSLAIPTCVSVCLEWWWYEFMI 225
              +L+  ++    +  +K  + P       WSS   +L +  PT +    E + +   +
Sbjct: 215 GAGILTYVIFKREEFQLRKGLVPPK------WSSQKEILRVGFPTAI----ENFVFSTGV 264

Query: 226 MMCG--LLVNPKATIASMGILIQTTSLVYVFPSSLSLGVSTRIGNELGANRPQKA----R 279
           +M    LL+      A   I I   SL ++    +S+ ++T +G   G    +      R
Sbjct: 265 LMFANILLIAGAEAYAGHRIGINVESLSFMPAFGISVAITTLVGRYNGMGNKEHVLGVIR 324

Query: 280 ISMIVSLFLAMVLGLGAMLFTTLMRNQWGKFFTNDREILELTSIVLPIVGLCELGNCPQT 339
              I+SL   + +G+   LF   +     + FT+D +I+E++ + + I+GL +      +
Sbjct: 325 QGWILSLLFQVTVGIIIFLFPEPLI----RIFTSDPQIIEISKLPVKIIGLFQFFLAIDS 380

Query: 340 TGCGVLRGSARPTIGANINLGSFYLVGMPVAIFLGFVAKLGFPGLWIGLLAAQGSCAMLM 399
           T  G LRG+        I   S +   +PVA  +    +LG  G WIG++A     + L 
Sbjct: 381 TMNGALRGTGNTLPPMIITFISIWTARLPVAFVMVKYFQLGLLGAWIGMIADIIFRSTLK 440

Query: 400 LVVLCRTDWN----LQVQRAKEL 418
           L+      W     L  +R KEL
Sbjct: 441 LLFFLSGKWEKRAVLTRERVKEL 463


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.326    0.141    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,875,489
Number of Sequences: 164201
Number of extensions: 2050188
Number of successful extensions: 6986
Number of sequences better than 10.0: 51
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 6912
Number of HSP's gapped (non-prelim): 62
length of query: 482
length of database: 59,974,054
effective HSP length: 114
effective length of query: 368
effective length of database: 41,255,140
effective search space: 15181891520
effective search space used: 15181891520
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 68 (30.8 bits)