BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC146866.2 + phase: 0 
         (504 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

SUT_SPIOL (Q03411) Sucrose transport protein (Sucrose permease) ...   515  e-145
SUT1_SCHPO (O14091) General alpha-glucoside permease                  144  4e-34
MATP_HUMAN (Q9UMX9) Membrane-associated transporter protein (AIM...   120  6e-27
MATP_MOUSE (P58355) Membrane-associated transporter protein (AIM...   120  1e-26
PRST_MOUSE (Q8K0H7) Prostein                                          112  2e-24
PRST_HUMAN (Q96JT2) Prostein                                          110  8e-24
PRST_MACFA (Q95KI5) Prostein (QmoA-10594/QtrA-11310)                  110  1e-23
PAST_MOUSE (Q8BIV7) Proton-associated sugar transporter A (PAST-...   110  1e-23
PAST_RAT (Q8K4S3) Proton-associated sugar transporter A (PAST-A)      109  1e-23
PAST_HUMAN (Q9Y2W3) Proton-associated sugar transporter A (PAST-...    54  1e-06
YD74_SYNY3 (P74168) Hypothetical symporter sll1374                     48  7e-05
LACY_LACDE (P22733) Lactose permease (Lactose-proton symporter) ...    42  0.005
LACY_STRTR (P23936) Lactose permease (Lactose-proton symporter) ...    40  0.011
YICJ_ECOLI (P31435) Hypothetical symporter yicJ                        40  0.014
YNAJ_BACSU (P94488) Hypothetical symporter ynaJ                        40  0.018
YAGG_ECOLI (P75683) Hypothetical symporter yagG                        38  0.053
YJMB_BACSU (O34961) Hypothetical symporter yjmB                        38  0.070
UIDB_ECOLI (P30868) Glucuronide carrier protein (Glucuronide per...    37  0.16
RAFP_PEDPE (P43466) Raffinose carrier protein (Raffinose permease)     37  0.16
MELB_ENTAE (O07366) Melibiose carrier protein (Thiomethylgalacto...    37  0.16

>SUT_SPIOL (Q03411) Sucrose transport protein (Sucrose permease)
           (Sucrose-proton symporter)
          Length = 525

 Score =  515 bits (1326), Expect = e-145
 Identities = 270/503 (53%), Positives = 333/503 (65%), Gaps = 17/503 (3%)

Query: 8   NPHRSRTRSSTSTSTSRPVQPVQPRTPLRQLLRVASVASGIQFGWALQLSLLTPYVQQLG 67
           N   ++   S+      P  P +    L++L  VASVA+G+QFGWALQLSLLTPYVQ LG
Sbjct: 8   NGENNKIAGSSLHLEKNPTTPPEAEATLKKLGLVASVAAGVQFGWALQLSLLTPYVQLLG 67

Query: 68  IPHKWASIIWLCGPVSGLFVQPLVGHLSDRCSSRFGRRRPFILVGAASIVVAVVIIGYAA 127
           IPH WA+ IWLCGP+SG+ VQPLVG+ SDRC+SRFGRRRPFI  GAA + VAV +IG+AA
Sbjct: 68  IPHTWAAYIWLCGPISGMIVQPLVGYYSDRCTSRFGRRRPFIAAGAALVAVAVGLIGFAA 127

Query: 128 DIGYLIGDDITQNYRPFAIVVFVIGFWILDVANNVTQGPCRALLADLTCNDARRTRVANA 187
           DIG   GD      +P AI VFV+GFWILDVANN  QGPCRALLAD+      +TR ANA
Sbjct: 128 DIGAASGDPTGNVAKPRAIAVFVVGFWILDVANNTLQGPCRALLADMAAGSQTKTRYANA 187

Query: 188 YFSLFMAVGNILGYATGSYSGWYKIFTFTLTPACSISCANLKSAFFLDVAFIVVTTY--L 245
           +FS FMA+GNI GYA GSYS  Y +F FT T AC + CANLKS FF+ +  ++V T   L
Sbjct: 188 FFSFFMALGNIGGYAAGSYSRLYTVFPFTKTAACDVYCANLKSCFFISITLLIVLTILAL 247

Query: 246 SIVSAHEVPLSSSGAGE--------SGSAEEAFMWELFGTFKYFSMPVWIVLSVTALTWI 297
           S+V   ++ +      E        SG A   F  +L G  K    P+ I+L VTAL WI
Sbjct: 248 SVVKERQITIDEIQEEEDLKNRNNSSGCARLPFFGQLIGALKDLPKPMLILLLVTALNWI 307

Query: 298 GWFPFNLFDTDWMGREIYGGDPEGGLIYDTGVRMGALGLLLNSVVLAVTSLLMERLCRK- 356
            WFPF LFDTDWMG+E+YGG    G +YD GV  GALGL++NSVVL V SL +E L R  
Sbjct: 308 AWFPFLLFDTDWMGKEVYGGTVGEGKLYDQGVHAGALGLMINSVVLGVMSLSIEGLARMV 367

Query: 357 RGAGFVWGISNIFMAICFIAMLVLTYAA------NSIGYVSKGQPPPTGIVIAALAIFTI 410
            GA  +WGI NI +A+C    +++T +A      + I   +   PPP G+   ALAIF +
Sbjct: 368 GGAKRLWGIVNIILAVCLAMTVLVTKSAEHFRDSHHIMGSAVPPPPPAGVKGGALAIFAV 427

Query: 411 LGFPMAITYSVPYALISTHIEPLGLGQGLSMGVLNLAIVVPQIVVSLGSGPWDQLFGGGN 470
           LG P+AIT+S+P+AL S      G GQGLS+GVLNLAIVVPQ+ VS+ SGPWD +FGGGN
Sbjct: 428 LGIPLAITFSIPFALASIFSASSGSGQGLSLGVLNLAIVVPQMFVSVTSGPWDAMFGGGN 487

Query: 471 SPAFAVAAVAALLSGLLALLAIP 493
            PAF V AVAA  S +L+   +P
Sbjct: 488 LPAFVVGAVAATASAVLSFTLLP 510


>SUT1_SCHPO (O14091) General alpha-glucoside permease
          Length = 553

 Score =  144 bits (364), Expect = 4e-34
 Identities = 99/332 (29%), Positives = 165/332 (48%), Gaps = 21/332 (6%)

Query: 17  STSTSTSRPVQPVQPRTPLRQLLRVASVASGIQFGWALQLSLLTPYVQQLGIPHKWASII 76
           S+    S P +   P      L+ +     G+Q  W+++L   TPY+  LG+  +W SII
Sbjct: 15  SSENEASSPFKESIPSRSSLYLIALTVSLLGVQLTWSVELGYGTPYLFSLGLRKEWTSII 74

Query: 77  WLCGPVSGLFVQPLVGHLSDRCSSRFGRRRPFILVGAASIVVAVVIIGYAADIG-YLIGD 135
           W+ GP++G+ +QP+ G LSDR +SR GRRRPF+L  +     ++ ++G+A DI  ++  +
Sbjct: 75  WIAGPLTGILIQPIAGILSDRVNSRIGRRRPFMLCASLLGTFSLFLMGWAPDICLFIFSN 134

Query: 136 DITQNYRPFAIVVFVIGFWILDVANNVTQGPCRALLADLTCNDARRTRVANAYFSLFMAV 195
           ++    +   IV+  I  ++LDVA NV     R+L+ D   +D +    AN++    + V
Sbjct: 135 EVLM--KRVTIVLATISIYLLDVAVNVVMASTRSLIVDSVRSDQQHE--ANSWAGRMIGV 190

Query: 196 GNILGYATGSYSGWYKIFTFTLTPACSISCANLKSAFFLDVAFIVVTTYLSIVSAHEVPL 255
           GN+LGY  G Y   Y+IF+F       + C     +  L V   + T ++S      V  
Sbjct: 191 GNVLGYLLG-YLPLYRIFSFLNFTQLQVFCVLASISLVLTVT--ITTIFVSERRFPPVEH 247

Query: 256 SSSGAGESGSAEEAFMWELFGTFK--YFSMPVWI--VLSVTALTWIGWFPFNLFDTDWMG 311
             S AGE        ++E F T +    ++P  +  +  V    + GWFPF  + T ++G
Sbjct: 248 EKSVAGE--------IFEFFTTMRQSITALPFTLKRICFVQFFAYFGWFPFLFYITTYVG 299

Query: 312 REIYGGDPEG-GLIYDTGVRMGALGLLLNSVV 342
                  P+G    +D   R G+  LLL +++
Sbjct: 300 ILYLRHAPKGHEEDWDMATRQGSFALLLFAII 331



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 21/56 (37%), Positives = 31/56 (54%), Gaps = 2/56 (3%)

Query: 404 ALAIFTILGFPMAITYSVPYALISTHIEPLGL--GQGLSMGVLNLAIVVPQIVVSL 457
           A A+  I G   A T  +PY+L S+ I  LGL    G  +GV N+ I  PQ++ ++
Sbjct: 451 AQAMVAICGLSWACTLWIPYSLFSSEIGKLGLRESSGKMIGVHNVFISAPQVLSTI 506


>MATP_HUMAN (Q9UMX9) Membrane-associated transporter protein (AIM-1
           protein) (Melanoma antigen AIM1)
          Length = 530

 Score =  120 bits (302), Expect = 6e-27
 Identities = 130/494 (26%), Positives = 199/494 (39%), Gaps = 90/494 (18%)

Query: 31  PRTPLRQLLRVASVASGIQFGWALQLSLLTPYVQQLGIPHKWASIIWLCGPVSGLFVQPL 90
           P+ P  +L+  +    G +F +A++ + +TP +  +G+P    SI+W   P+ G  +QP+
Sbjct: 28  PKRPTSRLIMHSMAMFGREFCYAVEAAYVTPVLLSVGLPSSLYSIVWFLSPILGFLLQPV 87

Query: 91  VGHLSDRCSSRFGRRRPFIL-VGAASIVVAVVIIGYAADIGYLIGDDITQNYRPFAIVVF 149
           VG  SD C SR+GRRRP+IL +G   +V   + +  A  +  LI +   +    +AI V 
Sbjct: 88  VGSASDHCRSRWGRRRPYILTLGVMMLVGMALYLNGATVVAALIAN--PRRKLVWAISVT 145

Query: 150 VIGFWILDVANNVTQGPCRALLADLTCNDARRTRVANAYFSLFMAVGNILGYATGSYSGW 209
           +IG  + D A +   GP +A L D+  +  +   +   Y +LF   G  LGY  G+   W
Sbjct: 146 MIGVVLFDFAADFIDGPIKAYLFDVCSHQDKEKGL--HYHALFTGFGGALGYLLGAID-W 202

Query: 210 YKIFTFTLTPACSISCANLKSAFFLDVAFIVVTTYLSIVSAHEV-------------PLS 256
             +    L            SA  L + F V    +S     EV             PLS
Sbjct: 203 AHLELGRLL-GTEFQVMFFFSALVLTLCFTVHLCSISEAPLTEVAKGIPPQQTPQDPPLS 261

Query: 257 SSGAGESGSAEE--------------------AFMWELFGTFKYF------SMPVWIVLS 290
           S G  E GS E+                    A       T K          P +  L 
Sbjct: 262 SDGMYEYGSIEKVKNGYVNPELAMQGAKNKNHAEQTRRAMTLKSLLRALVNMPPHYRYLC 321

Query: 291 VTALTWIGWFPF---NLFDTDWMGREIYGGDPEGG------LIYDTGVRMGALGLLLNSV 341
           ++ L  IGW  F    LF TD+MG+ +Y GDP         LIY+ GV +G  G  +NSV
Sbjct: 322 ISHL--IGWTAFLSNMLFFTDFMGQIVYRGDPYSAHNSTEFLIYERGVEVGCWGFCINSV 379

Query: 342 VLAVTSLLMERLCRKRGAGFVWGISNIFMAICFIAMLVLTYAANSIGYVSKGQPPPTGIV 401
             ++ S   + L    G             + F   L+       IG            V
Sbjct: 380 FSSLYSYFQKVLVSYIG----------LKGLYFTGYLLFGLGTGFIGLFPN--------V 421

Query: 402 IAALAIFTILGFPMAITYSVPYALISTHIE---------PLG------LGQGLSMGVLNL 446
            + L + ++ G   +  Y+VP+ LI+ +           P G       G+G+    L  
Sbjct: 422 YSTLVLCSLFGVMSSTLYTVPFNLITEYHREEEKERQQAPGGDPDNSVRGKGMDCATLTC 481

Query: 447 AIVVPQIVVSLGSG 460
            + + QI+V  G G
Sbjct: 482 MVQLAQILVGGGLG 495


>MATP_MOUSE (P58355) Membrane-associated transporter protein (AIM-1
           protein) (Melanoma antigen AIM1) (Underwhite protein)
          Length = 530

 Score =  120 bits (300), Expect = 1e-26
 Identities = 131/534 (24%), Positives = 213/534 (39%), Gaps = 122/534 (22%)

Query: 4   PTTTNPHRSRTRSSTSTSTSRPVQPVQPRTPLRQLLRVASVASGIQFGWALQLSLLTPYV 63
           PT T+ ++S        S        QP+    +L+  +    G +F +A++ + +TP +
Sbjct: 7   PTDTHTYQSLAEDCPFGSVE------QPKRSTGRLVMHSMAMFGREFCYAVEAAYVTPVL 60

Query: 64  QQLGIPHKWASIIWLCGPVSGLFVQPLVGHLSDRCSSRFGRRRPFILVGAASIVVAVVII 123
             +G+P    S++WL  P+ G  +QP+VG  SD C +R+GRRRP+IL  A  +++ + + 
Sbjct: 61  LSVGLPKSLYSMVWLLSPILGFLLQPVVGSASDHCRARWGRRRPYILTLAIMMLLGMAL- 119

Query: 124 GYAADIGYLIGDDITQ----NYRP---FAIVVFVIGFWILDVANNVTQGPCRALLADLTC 176
                  YL GD +      N R    +AI + ++G  + D + +   GP +A L D+  
Sbjct: 120 -------YLNGDAVVSALVANPRQKLIWAISITMVGVVLFDFSADFIDGPIKAYLFDVCS 172

Query: 177 NDARRTRVANAYFSLFMAVGNILGYATGSYSGWYKIFTFTLTPACSISCANLKSAFFLDV 236
           +  +   +   Y +LF   G  LGY  G+   W  +    L           +  FF   
Sbjct: 173 HQDKEKGL--HYHALFTGFGGALGYILGAID-WVHLDLGRLLG------TEFQVMFFFSA 223

Query: 237 AFIVVTTYLSIVSAHEVP------------------LSSSGAGESGSAEEA--------- 269
             +++     + S  E P                  LS+SG  E GS E+          
Sbjct: 224 LVLILCFITHLCSIPEAPLRDAATDPPSQQDPQGSSLSASGMHEYGSIEKVKNGGADTEQ 283

Query: 270 ------------------FMWELFGTFKYFSMPV-WIVLSVTALTWIGWFPF---NLFDT 307
                              M  L       +MP  +  L V+ L  IGW  F    LF T
Sbjct: 284 PVQEWKNKKPSGQSQRTMSMKSLLRAL--VNMPSHYRCLCVSHL--IGWTAFLSNMLFFT 339

Query: 308 DWMGREIYGGDPEGG------LIYDTGVRMGALGLLLNSVVLAVTSLLMERLCRKRGAGF 361
           D+MG+ +Y GDP G       LIY+ GV +G  GL +NSV  +V S   + +    G   
Sbjct: 340 DFMGQIVYHGDPYGAHNSTEFLIYERGVEVGCWGLCINSVFSSVYSYFQKAMVSYIG--- 396

Query: 362 VWGISNIFMAICFIAMLVLTYAANSIGYVSKGQPPPTGIVIAALAIFTILGFPMAITYSV 421
                     + F+  L+       IG            V + L + ++ G   +  Y+V
Sbjct: 397 -------LKGLYFMGYLLFGLGTGFIGLFPN--------VYSTLVLCSMFGVMSSTLYTV 441

Query: 422 PYALISTH---------------IEPLGLGQGLSMGVLNLAIVVPQIVVSLGSG 460
           P+ LI+ +                +  G G+G+    L   + + QI+V  G G
Sbjct: 442 PFNLIAEYHREEEKEKGQEAPGGPDNQGRGKGVDCAALTCMVQLAQILVGGGLG 495


>PRST_MOUSE (Q8K0H7) Prostein
          Length = 553

 Score =  112 bits (281), Expect = 2e-24
 Identities = 105/410 (25%), Positives = 178/410 (42%), Gaps = 40/410 (9%)

Query: 37  QLLRVASVASGIQFGWALQLSLLTPYVQQLGIPHKWASIIWLCGPVSGLFVQPLVGHLSD 96
           QLL V  +  G++   A  ++ + P + ++G+  K+ +++   GPV GL   PL+G  SD
Sbjct: 17  QLLLVNLLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLVSVPLLGSASD 76

Query: 97  RCSSRFGRRRPFILVGAASIVVAVVIIGYAADIGYLIGDDITQNYRPFAIVVFVIGFWIL 156
           +   R+GRRRPFI   +  +++++ +I  A  +  L+  D     RP  + + ++G  +L
Sbjct: 77  QWRGRYGRRRPFIWALSLGVLLSLFLIPRAGWLAGLLYPDT----RPLELALLILGVGLL 132

Query: 157 DVANNVTQGPCRALLADLTCNDARRTRVANAYFSLFMAVGNILGYATGSYSGWYKIFTFT 216
           D    V   P  ALL+DL   D    R A + ++  +++G  LGY   +      +    
Sbjct: 133 DFCGQVCFTPLEALLSDL-FRDPDHCRQAFSVYAFMISLGGCLGYLLPAIDWDTSVLAPY 191

Query: 217 LTPACSISCANLKSAFFLDVAFIVVTTYLSIVSAHEVP---LSSSGAGESGSAEEAFMWE 273
           L          L   F + +A  +  T  +++   E     L S+ +           + 
Sbjct: 192 LGTQEECLFGLLTLIFLICMAATLFVTEEAVLGPPEPAEGLLVSAVSRRCCPCHVGLAFR 251

Query: 274 LFGTF------KYFSMPVWI--VLSVTALTWIGWFPFNLFDTDWMGREIYGGDP------ 319
             GT           MP  +  +      +W+    F LF TD++G  +Y G P      
Sbjct: 252 NLGTLFPRLQQLCCRMPRTLRRLFVAELCSWMALMTFTLFYTDFVGEGLYQGVPRAEPGT 311

Query: 320 EGGLIYDTGVRMGALGLLLNSVVLAVTSLLMERLCRKRGAGFVWGISNIFMAICFIAMLV 379
           E    YD G+RMG+LGL L   +  V SL+M+RL +K G   V+    +   + F     
Sbjct: 312 EARRHYDEGIRMGSLGLFLQCAISLVFSLVMDRLVQKFGTRSVY----LASVMTFPVAAA 367

Query: 380 LTYAANSIGYVSKGQPPPTGIVIAALAIFTILGFPMAITYSVPYALISTH 429
            T  ++S+            +V+ A A  T  GF  +    +PY L S +
Sbjct: 368 ATCLSHSV------------VVVTASAALT--GFTFSALQILPYTLASLY 403


>PRST_HUMAN (Q96JT2) Prostein
          Length = 553

 Score =  110 bits (275), Expect = 8e-24
 Identities = 110/413 (26%), Positives = 182/413 (43%), Gaps = 46/413 (11%)

Query: 37  QLLRVASVASGIQFGWALQLSLLTPYVQQLGIPHKWASIIWLCGPVSGLFVQPLVGHLSD 96
           QLL V  +  G++   A  ++ + P + ++G+  K+ +++   GPV GL   PL+G  SD
Sbjct: 17  QLLLVNLLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLVCVPLLGSASD 76

Query: 97  RCSSRFGRRRPFILVGAASIVVAVVIIGYAADIGYLIGDDITQNYRPFAIVVFVIGFWIL 156
               R+GRRRPFI   +  I++++ +I  A   G+L G  +  + RP  + + ++G  +L
Sbjct: 77  HWRGRYGRRRPFIWALSLGILLSLFLIPRA---GWLAG-LLCPDPRPLELALLILGVGLL 132

Query: 157 DVANNVTQGPCRALLADLTCNDARRTRVANAYFSLFMAVGNILGY----------ATGSY 206
           D    V   P  ALL+DL   D    R A + ++  +++G  LGY          A   Y
Sbjct: 133 DFCGQVCFTPLEALLSDL-FRDPDHCRQAYSVYAFMISLGGCLGYLLPAIDWDTSALAPY 191

Query: 207 SGWYKIFTFTLTPACSISC--ANLKSAFFLDVAFIVVTTYLSI--VSAHEVPLSSSGAGE 262
            G  +   F L     ++C  A L  A    +        LS   +S H  P  +  A  
Sbjct: 192 LGTQEECLFGLLTLIFLTCVAATLLVAEEAALGPTEPAEGLSAPSLSPHCCPCRARLAFR 251

Query: 263 SGSAEEAFMWELFGTFKYFSMPVWIVLSVTALTWIGWFPFNLFDTDWMGREIYGGDP--- 319
           +  A    + +L          +++       +W+    F LF TD++G  +Y G P   
Sbjct: 252 NLGALLPRLHQLCCRMPRTLRRLFV---AELCSWMALMTFTLFYTDFVGEGLYQGVPRAE 308

Query: 320 ---EGGLIYDTGVRMGALGLLLNSVVLAVTSLLMERLCRKRGAGFVWGISNIFMAICFIA 376
              E    YD GVRMG+LGL L   +  V SL+M+RL ++ G   V+        +  +A
Sbjct: 309 PGTEARRHYDEGVRMGSLGLFLQCAISLVFSLVMDRLVQRFGTRAVY--------LASVA 360

Query: 377 MLVLTYAANSIGYVSKGQPPPTGIVIAALAIFTILGFPMAITYSVPYALISTH 429
              +   A  + +          +V A+ A   + GF  +    +PY L S +
Sbjct: 361 AFPVAAGATCLSH-------SVAVVTASAA---LTGFTFSALQILPYTLASLY 403


>PRST_MACFA (Q95KI5) Prostein (QmoA-10594/QtrA-11310)
          Length = 553

 Score =  110 bits (274), Expect = 1e-23
 Identities = 108/426 (25%), Positives = 178/426 (41%), Gaps = 72/426 (16%)

Query: 37  QLLRVASVASGIQFGWALQLSLLTPYVQQLGIPHKWASIIWLCGPVSGLFVQPLVGHLSD 96
           QLL +  +  G++   A  ++ + P + ++G+  K+ +++   GPV GL   PL+G  SD
Sbjct: 17  QLLLINLLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLVSVPLLGSASD 76

Query: 97  RCSSRFGRRRPFILVGAASIVVAVVIIGYAADIGYLIGDDITQNYRPFAIVVFVIGFWIL 156
               R+GRRRPFI   +  I++++ +I  A   G+L G  +  + RP  + + ++G  +L
Sbjct: 77  HWRGRYGRRRPFIWALSLGILLSLFLIPRA---GWLAG-LLCPDPRPLELALLILGVGLL 132

Query: 157 DVANNVTQGPCRALLADLTCNDARRTRVANAYFSLFMAVGNILGYATGSYSGWYKIFTFT 216
           D    V   P  ALL+DL   D    R A + ++  +++G  LGY   +   W    T  
Sbjct: 133 DFCGQVCFTPLEALLSDL-FRDPDHCRQAYSVYAFMISLGGCLGYLLPAID-W---DTSA 187

Query: 217 LTPACSISCANLKSAFFLDVAFIVVTTYLSIVSAHEVPLSSSGAGESGSAEEAFMWELFG 276
           L P         +  F L     +     +++ A E  L  +   E  SA          
Sbjct: 188 LAPYLG---TQEECLFGLLTLIFLTCVAATLLVAEEAALGPAEPAEGLSAP--------- 235

Query: 277 TFKYFSMPVWIVLSVTAL---------------------------TWIGWFPFNLFDTDW 309
           +      P W  L+   L                           +W+    F LF TD+
Sbjct: 236 SLPSHCCPCWARLAFRNLGALLPRLHQLCCRMPRTLRRLFVAELCSWMALMTFTLFYTDF 295

Query: 310 MGREIYGGDPEGGL------IYDTGVRMGALGLLLNSVVLAVTSLLMERLCRKRGAGFVW 363
           +G  +Y G P   L       YD GVRMG+LGL L   +  V SL+M+RL ++ G   V+
Sbjct: 296 VGEGLYQGVPRAELGTEARRHYDEGVRMGSLGLFLQCAISLVFSLVMDRLVQRFGTRAVY 355

Query: 364 GISNIFMAICFIAMLVLTYAANSIGYVSKGQPPPTGIVIAALAIFTILGFPMAITYSVPY 423
                   +  +A   +   A  + +          +V A+ A   + GF  +    +PY
Sbjct: 356 --------LASVAAFPVAAGATCLSH-------SVAVVTASAA---LTGFTFSALQILPY 397

Query: 424 ALISTH 429
            L S +
Sbjct: 398 TLASLY 403


>PAST_MOUSE (Q8BIV7) Proton-associated sugar transporter A (PAST-A)
           (Deleted in neuroblastoma 5 protein homolog) (DNb-5
           homolog)
          Length = 751

 Score =  110 bits (274), Expect = 1e-23
 Identities = 70/231 (30%), Positives = 116/231 (49%), Gaps = 11/231 (4%)

Query: 29  VQPRTPLRQLLRVASVASGIQFGWALQLSLLTPYVQQLGIPHKWASIIWLCGPVSGLFVQ 88
           + P+    +LL    +  GI+F +A++ + +TP + Q+G+P +  S++W   P+ G  +Q
Sbjct: 78  LHPQRSFWELLFNGCILFGIEFSYAMETAYVTPVLLQMGLPDQLYSLVWFISPILGFLLQ 137

Query: 89  PLVGHLSDRCSSRFGRRRPFILVGAASIVVAVVIIGYAADIGYLIGDDITQNYRPFAIVV 148
           PL+G  SDRC+SRFGRRRPFILV A   ++ + ++    DIG  + D  T +   + I++
Sbjct: 138 PLLGAWSDRCTSRFGRRRPFILVLAIGALLGLSLLLNGRDIGMALADTATNH--KWGILL 195

Query: 149 FVIGFWILDVANNVTQGPCRALLADLTCNDARRTRVANAYFSLFMAVGNILGYATGSYSG 208
            V G  ++D + +    P  A + D+ C    + R  N + +L   +G   GY  G    
Sbjct: 196 TVCGVVLMDFSADSADNPSHAXMMDV-CGPVDQDRGLNIH-ALMAGLGGGFGYVVGGIH- 252

Query: 209 WYKIFTFTLTPACSISCANLKSAFFLDVAFIVVTTYLSIVSAHEVPLSSSG 259
           W K      T         L+  +      + VTT L+++S  E PL   G
Sbjct: 253 WDK------TSFGRALGGQLRVIYVFTAITLSVTTVLTLISIPERPLRPLG 297



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 51/220 (23%), Positives = 88/220 (39%), Gaps = 40/220 (18%)

Query: 296 WIGWFPFN---LFDTDWMGREIYGGDP------EGGLIYDTGVRMGALGLLLNSVVLAVT 346
           ++GW  F    LF TD+MG  ++ GDP      E    Y++GV MG  G+ + +   A  
Sbjct: 534 FLGWLSFEGMLLFYTDFMGEVVFQGDPKAPHTSEAYQKYNSGVTMGCWGMCIYAFSAAFY 593

Query: 347 SLLMERLCRKRGAGFVWGISNIFMAICFIAMLVLTYAANSIGYVSKGQPPPTGIVIAALA 406
           S ++E+L                  +    +  + Y A  +G    G    +  +   L+
Sbjct: 594 SAILEKLEE---------------CLSVRTLYFIAYLAFGLG---TGLATLSRNLYVVLS 635

Query: 407 IFTILGFPMAITYSVPYALISTHIEPLGL----------GQGLSMGVLNLAIVVPQIVVS 456
           + T  G   +   ++PY+L+  + +              G G+ + +L+    + QI+VS
Sbjct: 636 LCTTYGILFSTLCTLPYSLLCDYYQSKKFAGSSADGTRRGMGVDISLLSCQYFLAQILVS 695

Query: 457 LGSGPWDQLFGGGNSPAF---AVAAVAALLSGLLALLAIP 493
           L  GP     G  N   +    V+ +  L S L     IP
Sbjct: 696 LVLGPLTSAVGSANGVMYFSSLVSFLGCLYSSLCVTYEIP 735


>PAST_RAT (Q8K4S3) Proton-associated sugar transporter A (PAST-A)
          Length = 751

 Score =  109 bits (273), Expect = 1e-23
 Identities = 70/233 (30%), Positives = 116/233 (49%), Gaps = 11/233 (4%)

Query: 27  QPVQPRTPLRQLLRVASVASGIQFGWALQLSLLTPYVQQLGIPHKWASIIWLCGPVSGLF 86
           + + P+    +LL    +  GI+F +A++ + +TP + Q+G+P +  S++W   P+ G  
Sbjct: 76  EDLHPQRSFWELLFNGCILFGIEFSYAMETAYVTPVLLQMGLPDQLYSLVWFISPILGFL 135

Query: 87  VQPLVGHLSDRCSSRFGRRRPFILVGAASIVVAVVIIGYAADIGYLIGDDITQNYRPFAI 146
           +QPL+G  SDRC+SRFGRRRPFILV A   ++ + ++    DIG  + D  T +   + I
Sbjct: 136 LQPLLGAWSDRCTSRFGRRRPFILVLAIGALLGLSLLLNGRDIGMALADTATNH--KWGI 193

Query: 147 VVFVIGFWILDVANNVTQGPCRALLADLTCNDARRTRVANAYFSLFMAVGNILGYATGSY 206
           ++ V G  ++D + +    P  A + D+ C    + R  N + +L   +G   GY  G  
Sbjct: 194 LLTVCGVVLMDFSADSADNPSHAYMMDV-CGPVDQDRGLNIH-ALMAGLGGGFGYVVGGI 251

Query: 207 SGWYKIFTFTLTPACSISCANLKSAFFLDVAFIVVTTYLSIVSAHEVPLSSSG 259
             W K      T         L+  +      + VTT  ++VS  E PL   G
Sbjct: 252 H-WDK------TSFGRALGGQLRVIYIFTAITLSVTTVFTLVSIPERPLRPLG 297



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 51/220 (23%), Positives = 89/220 (40%), Gaps = 40/220 (18%)

Query: 296 WIGWFPFN---LFDTDWMGREIYGGDP------EGGLIYDTGVRMGALGLLLNSVVLAVT 346
           ++GW  F    LF TD+MG  ++ GDP      E    Y++GV MG  G+ + +   A  
Sbjct: 534 FLGWLSFEGMLLFYTDFMGEVVFQGDPKAPHASEAYQKYNSGVTMGCWGMCIYAFSAAFY 593

Query: 347 SLLMERLCRKRGAGFVWGISNIFMAICFIAMLVLTYAANSIGYVSKGQPPPTGIVIAALA 406
           S ++E+L                     +++  L + A  +  +  G    +  +   L+
Sbjct: 594 SAILEKLEE------------------CLSVRTLYFIAYLLFGLGTGLATLSRNLYVVLS 635

Query: 407 IFTILGFPMAITYSVPYALISTHIEPLGL----------GQGLSMGVLNLAIVVPQIVVS 456
           + T  G   +   ++PY+L+  + +              G G+ + +L+    + QI+VS
Sbjct: 636 LCTHYGILFSTLCTLPYSLLCDYYQSKKFAGSSADGTRRGMGVDISLLSCQYFLAQILVS 695

Query: 457 LGSGPWDQLFGGGNSP---AFAVAAVAALLSGLLALLAIP 493
           L  GP     G  N     A  V+ +  L S L     IP
Sbjct: 696 LVLGPLTSAVGSANGVMYFASLVSFLGCLYSSLCVTYEIP 735


>PAST_HUMAN (Q9Y2W3) Proton-associated sugar transporter A (PAST-A)
           (Deleted in neuroblastoma 5 protein) (DNb-5) (Fragment)
          Length = 509

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 54/228 (23%), Positives = 94/228 (40%), Gaps = 56/228 (24%)

Query: 296 WIGWFPFN---LFDTDWMGREIYGGDP------EGGLIYDTGVRMGALGLLLNSVVLAVT 346
           ++GW  F    LF TD+MG  ++ GDP      E    Y++GV MG  G+ + +   A  
Sbjct: 292 FLGWLSFEGMLLFYTDFMGEVVFQGDPKAPHTSEAYQKYNSGVTMGCWGMCIYAFSAAFY 351

Query: 347 SLLMERLCRKRGAGFVWGISNIFMAICFIAMLVLTYAANSIGYVSKGQPPPTGIVIAALA 406
           S ++E+L               F+++    +  + Y A  +G         TG+   +  
Sbjct: 352 SAILEKL-------------EEFLSV--RTLYFIAYLAFGLG---------TGLATLSRN 387

Query: 407 IFTILGFPMAITYSV--------PYALISTHIEPLGL----------GQGLSMGVLNLAI 448
           ++ +L   + ITY +        PY+L+  + +              G G+ + +L+   
Sbjct: 388 LYVVLS--LCITYGILFSTLCTLPYSLLCDYYQSKKFAGSSADGTRRGMGVDISLLSCQY 445

Query: 449 VVPQIVVSLGSGPWDQLFGGGNSPAF---AVAAVAALLSGLLALLAIP 493
            + QI+VSL  GP     G  N   +    V+ +  L S L  +  IP
Sbjct: 446 FLAQILVSLVLGPLTSAVGSANGVMYFSSLVSFLGCLYSSLFVIYEIP 493


>YD74_SYNY3 (P74168) Hypothetical symporter sll1374
          Length = 544

 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 45/157 (28%), Positives = 70/157 (43%), Gaps = 15/157 (9%)

Query: 50  FGWALQLSLLTPYV-----QQLGIPHKWASIIWLCGPVSGLFVQPLVGHLSDRCSSRFGR 104
           FG A+  ++L  Y+        GIP   A  + + G +      P++G LSDR  SR+GR
Sbjct: 23  FGPAITANILVFYLLFFLTDVAGIPAALAGSVLMIGKIFDAINDPIIGLLSDRTRSRWGR 82

Query: 105 RRPFILVGAASIVVAVVIIGYAAD--IGYLIGDDITQNYRPFAIVVFVIGFWILDVANNV 162
           R P++L G          + Y A   I +   D +T  +  F  + +V      ++    
Sbjct: 83  RLPWMLGGMIPFA-----LFYTAQWLIPHFSDDRLTNQWGLF--IYYVAIAMAFNLCYTT 135

Query: 163 TQGPCRALLADLTCNDARRTRVANAYFSLFMAVGNIL 199
              P  AL  +LT N   RTR+ N++   F   G+IL
Sbjct: 136 VNLPYTALTPELTQNYNERTRL-NSFRFAFSIGGSIL 171


>LACY_LACDE (P22733) Lactose permease (Lactose-proton symporter)
           (Lactose transport protein)
          Length = 627

 Score = 41.6 bits (96), Expect = 0.005
 Identities = 41/190 (21%), Positives = 84/190 (43%), Gaps = 13/190 (6%)

Query: 82  VSGLFVQPLVGHLSDRCSSRFGRRRPFILVGAASIVVAVVIIGYAADIGYLIGDDITQNY 141
           +  + + PL+G+  DR  SR+G+ +P+++ G   I+ ++ ++    D G      I Q+ 
Sbjct: 58  IGEVLLDPLIGNAIDRTESRWGKFKPWVVGG--GIISSLALLALFTDFG-----GINQSK 110

Query: 142 RPFAIVVFVIGFWILDVANNVTQGPCRALLADLTCNDARRTRVANAYFSLFMAVGNILGY 201
               +V+F I + I+D+  +       A++  L+ +   R +      S F  VG+ +G 
Sbjct: 111 PVVYLVIFGIVYLIMDIFYSFKDTGFWAMIPALSLDSREREKT-----STFARVGSTIGA 165

Query: 202 ATGSYSGWYKIFTFTLTPACSISCANLKSAFFLDVAFIVVTTYLSI-VSAHEVPLSSSGA 260
                     I  F+ + A           F L VA + + T +++ +  HEV  +   +
Sbjct: 166 NLVGVVITPIILFFSASKANPNGDKQGWFFFALIVAIVGILTSITVGLGTHEVKSALRES 225

Query: 261 GESGSAEEAF 270
            E  + ++ F
Sbjct: 226 NEKTTLKQVF 235


>LACY_STRTR (P23936) Lactose permease (Lactose-proton symporter)
           (Lactose transport protein)
          Length = 634

 Score = 40.4 bits (93), Expect = 0.011
 Identities = 41/191 (21%), Positives = 91/191 (47%), Gaps = 21/191 (10%)

Query: 85  LFVQPLVGHLSDRCSSRFGRRRPFILVGAASIVVAVVIIGYAADIGYLIGDDITQNYRPF 144
           +F+ PL+G++ D  ++++G+ +P+++ G   I+ ++ ++    D+G L          PF
Sbjct: 68  VFIDPLIGNMIDNTNTKYGKFKPWVVGG--GIISSITLLLLFTDLGGL------NKTNPF 119

Query: 145 A-IVVFVIGFWILDVANNVTQGPCRALLADLTCNDARRTRVANAYFSLFMAVGNILGYAT 203
             +V+F I + ++DV  ++      +++  L+ +   R ++A      F  +G+ +G   
Sbjct: 120 LYLVLFGIIYLVMDVFYSIKDIGFWSMIPALSLDSHEREKMAT-----FARIGSTIGANI 174

Query: 204 GSYSGWYKIFTFTLTPACSISCANLKSAFF---LDVAFIVVTTYLSI-VSAHEVPLSSSG 259
              +    +  F++T   + S +  KS +F     VA I V T +++ +   EV      
Sbjct: 175 VGVAIMPIVLFFSMT---NNSGSGDKSGWFWFAFIVALIGVITSIAVGIGTREVESKIRD 231

Query: 260 AGESGSAEEAF 270
             E  S ++ F
Sbjct: 232 NNEKTSLKQVF 242


>YICJ_ECOLI (P31435) Hypothetical symporter yicJ
          Length = 460

 Score = 40.0 bits (92), Expect = 0.014
 Identities = 35/143 (24%), Positives = 64/143 (44%), Gaps = 11/143 (7%)

Query: 54  LQLSLLTPYVQQLGIPHKWASIIWLCGPVSGLFVQPLVGHLSDRCSSRFGRRRPFILVGA 113
           + L ++  Y    GIP  +   ++L          P +G L+DR  SR+G+ RP++L GA
Sbjct: 28  VMLYMMFFYTDIFGIPAGFVGTMFLVARALDAISDPCMGLLADRTRSRWGKFRPWVLFGA 87

Query: 114 ASIVVAVVIIGYAADIGYLIGDDITQNYRPFAIVVFVIGFWILDVANNVTQGPCRALLAD 173
               + V ++ Y+         D++ N +   ++   I + +L +   V   P  AL   
Sbjct: 88  LPFGI-VCVLAYST-------PDLSMNGK---MIYAAITYTLLTLLYTVVNIPYCALGGV 136

Query: 174 LTCNDARRTRVANAYFSLFMAVG 196
           +T +  +R  + +  F L  A G
Sbjct: 137 ITNDPTQRISLQSWRFVLATAGG 159


>YNAJ_BACSU (P94488) Hypothetical symporter ynaJ
          Length = 463

 Score = 39.7 bits (91), Expect = 0.018
 Identities = 26/84 (30%), Positives = 40/84 (46%), Gaps = 3/84 (3%)

Query: 58  LLTPYVQQLGIPHKWASIIWLCGPVSGLFVQPLVGHLSDRCSSRFGRRRPFILVGAASIV 117
           LL  Y    G+    A  ++L   +      P +G + DR +SRF R RP++L GA   V
Sbjct: 35  LLFFYTDVFGLSAAAAGTMFLVVRIIDALADPFIGTIVDRTNSRFARFRPYLLFGAFPFV 94

Query: 118 VAVVIIGYA---ADIGYLIGDDIT 138
           +  ++       +D+G LI   IT
Sbjct: 95  ILAILCFTTPDFSDMGKLIYAYIT 118


>YAGG_ECOLI (P75683) Hypothetical symporter yagG
          Length = 460

 Score = 38.1 bits (87), Expect = 0.053
 Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 1/80 (1%)

Query: 50  FGWALQLSLLTP-YVQQLGIPHKWASIIWLCGPVSGLFVQPLVGHLSDRCSSRFGRRRPF 108
           F W   + LL   Y    G+       ++L   V      PL+G L DR  +R G+ RPF
Sbjct: 21  FVWQATMFLLAYFYTDVFGLSAGIMGTLFLVSRVLDAVTDPLMGLLVDRTRTRHGQFRPF 80

Query: 109 ILVGAASIVVAVVIIGYAAD 128
           +L GA    +  V+  Y  D
Sbjct: 81  LLWGAIPFGIVCVLTFYTPD 100


>YJMB_BACSU (O34961) Hypothetical symporter yjmB
          Length = 459

 Score = 37.7 bits (86), Expect = 0.070
 Identities = 37/149 (24%), Positives = 68/149 (44%), Gaps = 24/149 (16%)

Query: 55  QLSLLTPYVQQLGIPHKWASIIWLCGPVSGLFVQPLVGHLSD--RCSSRFGRRRPFILVG 112
           Q+ LL  +    GIP   A  I+L   +      P+VG   D  +   + G+ RP++L+G
Sbjct: 41  QIYLLKYFTDVAGIPAAMAGGIFLVSKLFAAITDPIVGSSIDYRKNIGKRGKFRPYLLIG 100

Query: 113 AASIVVAVVIIGYAADI---GYLIGDDITQNYRPFAIVVFVIGFWILDVANNVTQGPCRA 169
           +  + V  V+I  + ++   G LI       Y   + +++ IG+  +++       P  +
Sbjct: 101 SIVLAVLTVLIFLSPNVSTTGKLI-------YAYASYMIWGIGYSFVNI-------PYGS 146

Query: 170 LLADLTCNDARRTRVANAYFSLFMAVGNI 198
           L A +T N   RT +     S F  +G++
Sbjct: 147 LGAAMTQNSEDRTSI-----STFRQIGSL 170


>UIDB_ECOLI (P30868) Glucuronide carrier protein (Glucuronide
           permease)
          Length = 457

 Score = 36.6 bits (83), Expect = 0.16
 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 1/83 (1%)

Query: 41  VASVASGIQFGWALQLSLLTPYVQQLGIPHKWASIIWLCGPVSGLFVQPLVGHLSDRCSS 100
           +  VA+   F     L LL+ Y    G+    A  + L   V   F     G + D  ++
Sbjct: 15  LGDVANNFAFAMGA-LFLLSYYTDVAGVGAAAAGTMLLLVRVFDAFADVFAGRVVDSVNT 73

Query: 101 RFGRRRPFILVGAASIVVAVVII 123
           R+G+ RPF+L G A +++  V++
Sbjct: 74  RWGKFRPFLLFGTAPLMIFSVLV 96



 Score = 32.0 bits (71), Expect = 3.8
 Identities = 30/116 (25%), Positives = 57/116 (48%), Gaps = 12/116 (10%)

Query: 331 MGALGLLLNSVVLAVTSLLMERLCRKRGAGFVWGISNIFMAICFIAMLVLTYAANSI--G 388
           +GAL +L+++  ++ +SL   R        +V   + +F  +  +  LV T A+  +  G
Sbjct: 235 IGALCVLISTFAVSASSLFYVR--------YVLNDTGLFTVLVLVQNLVGTVASAPLVPG 286

Query: 389 YVSKGQPPPTGIVIAALAIFTILGFPMAITYSVPYALISTHIEPLGLGQGLSMGVL 444
            V++     T ++ A L     L F     +S+P AL++  I    +GQG++M V+
Sbjct: 287 MVARIGKKNTFLIGALLGTCGYLLFFWVSVWSLPVALVALAI--ASIGQGVTMTVM 340


>RAFP_PEDPE (P43466) Raffinose carrier protein (Raffinose permease)
          Length = 641

 Score = 36.6 bits (83), Expect = 0.16
 Identities = 27/116 (23%), Positives = 54/116 (46%), Gaps = 12/116 (10%)

Query: 85  LFVQPLVGHLSDRCSSRFGRRRPFILVGAASIVVAVVIIGYAADIGYLIGDDITQNYRPF 144
           LF+ P +G+  DR  +  G  RP+++VG    V +++++    ++G L   +        
Sbjct: 70  LFIDPFIGNAIDRTKNSPGHFRPWVVVGGT--VSSIILLLLFTNLGGLYAKNAM-----I 122

Query: 145 AIVVFVIGFWILDVANNVTQGPCRALLADLTCNDARRTRVANAYFSLFMAVGNILG 200
            +VVF I +  +D+  +       ++L  LT +   R + A      F  +G+ +G
Sbjct: 123 YLVVFAILYITMDIFYSFKDVGFWSMLPSLTTDSREREKTAT-----FARLGSTIG 173


>MELB_ENTAE (O07366) Melibiose carrier protein
           (Thiomethylgalactoside permease II) (Melibiose permease)
           (Na+ (Li+)/melibiose symporter) (Melibiose transporter)
          Length = 471

 Score = 36.6 bits (83), Expect = 0.16
 Identities = 45/220 (20%), Positives = 91/220 (40%), Gaps = 44/220 (20%)

Query: 58  LLTPYVQQLGIPHKWASIIWLCGPVSGLFVQPLVGHLSDRCSSRFGRRRPFILVGAA--S 115
           L+  Y   +G+       ++L   +      P++G + +   SR+G+ +P+IL+G    S
Sbjct: 29  LMYYYTDIVGLSVGVVGTLFLVARILDAIADPIMGWIVNCTRSRWGKFKPWILIGTITNS 88

Query: 116 IVVAVVIIGYAADIGYLIGDD-ITQNYRPFAIVVFVIGFWILDVANNVTQGPCRALLADL 174
           +V+ ++   +    G L+    +T     F   +  + FW              +L+  +
Sbjct: 89  VVLYMLFSAHHFSGGALLAWVWLTYLLWGFTYTIMDVPFW--------------SLVPTI 134

Query: 175 TCNDARRTRVAN-----AYFSLFMAVGNILGYAT---GSYSGW-YKIFTFTLTPACSISC 225
           T +   R ++       A  + F+  G  L + +   G+  G+ +++FT  L        
Sbjct: 135 TLDKREREQLVPYPRFFASLAGFVTAGVTLPFVSAVGGADRGFGFQMFTLVL-------- 186

Query: 226 ANLKSAFFLDVAFIVVTTYLSIVSAHEVPLSSSGAGESGS 265
                     +AF V++T +++ + HEV  S SG  E  S
Sbjct: 187 ----------IAFFVISTLVTLRNVHEVYSSDSGVSEDSS 216


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.325    0.140    0.437 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,904,816
Number of Sequences: 164201
Number of extensions: 2534945
Number of successful extensions: 8656
Number of sequences better than 10.0: 41
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 8598
Number of HSP's gapped (non-prelim): 54
length of query: 504
length of database: 59,974,054
effective HSP length: 115
effective length of query: 389
effective length of database: 41,090,939
effective search space: 15984375271
effective search space used: 15984375271
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 68 (30.8 bits)