BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC146856.6 - phase: 0 /pseudo
(335 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CBP_MOUSE (P45481) CREB-binding protein (EC 2.3.1.48) 55 2e-07
CBP_HUMAN (Q92793) CREB-binding protein (EC 2.3.1.48) 54 6e-07
P300_HUMAN (Q09472) E1A-associated protein p300 (EC 2.3.1.48) 53 1e-06
YLJ8_CAEEL (P34371) Hypothetical protein C50C3.8 in chromosome III 50 8e-06
CBP1_CAEEL (P34545) Protein cbp-1 46 1e-04
BTB9_HUMAN (Q96Q07) BTB/POZ domain containing protein 9 44 4e-04
BTB9_MOUSE (Q8C726) BTB/POZ domain containing protein 9 43 0.001
YNV5_CAEEL (P34568) Hypothetical protein T16H12.5 in chromosome III 42 0.002
SPOP_MOUSE (Q6ZWS8) Speckle-type POZ protein (PDX-1 C-terminal i... 40 0.008
SPOP_HUMAN (O43791) Speckle-type POZ protein 40 0.008
BTB2_HUMAN (Q9BX70) BTB/POZ domain containing protein 2 38 0.031
BTB3_MOUSE (P58545) BTB/POZ domain containing protein 3 35 0.26
BTB3_HUMAN (Q9Y2F9) BTB/POZ domain containing protein 3 35 0.26
BTB1_HUMAN (Q9H0C5) BTB/POZ domain containing protein 1 (Hepatit... 35 0.26
BTB1_MOUSE (P58544) BTB/POZ domain containing protein 1 (Glucose... 34 0.45
PR18_HUMAN (Q99633) Pre-mRNA splicing factor 18 (PRP18 homolog) ... 33 0.77
PR18_RAT (Q9JKB8) Pre-mRNA splicing factor 18 (PRP18 homolog) (P... 33 1.3
ZY28_HUMAN (Q9HCC9) Zinc finger FYVE domain containing protein 28 32 1.7
PR18_MOUSE (Q8BM39) Pre-mRNA splicing factor 18 (PRP18 homolog) 32 1.7
TS13_MOUSE (Q01755) Testis-specific protein PBS13 32 2.2
>CBP_MOUSE (P45481) CREB-binding protein (EC 2.3.1.48)
Length = 2441
Score = 55.1 bits (131), Expect = 2e-07
Identities = 33/107 (30%), Positives = 53/107 (48%), Gaps = 14/107 (13%)
Query: 229 DEENSKKERIRKMNEREVYLQLYDAMEALVHICRDGCRTIGPHDKDFKANQPCRYTSCKG 288
DE +S+ E K + L + +++LVH C+ CR N C SC+
Sbjct: 1752 DEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQ--CR-----------NANCSLPSCQK 1798
Query: 289 LELLVRHFAGCKLRVPGGCGHCKRMWQLLELHSRLCADPDFCRVPLC 335
++ +V+H GCK + GGC CK++ L H++ C + + C VP C
Sbjct: 1799 MKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQE-NKCPVPFC 1844
>CBP_HUMAN (Q92793) CREB-binding protein (EC 2.3.1.48)
Length = 2442
Score = 53.9 bits (128), Expect = 6e-07
Identities = 32/107 (29%), Positives = 53/107 (48%), Gaps = 14/107 (13%)
Query: 229 DEENSKKERIRKMNEREVYLQLYDAMEALVHICRDGCRTIGPHDKDFKANQPCRYTSCKG 288
DE +S+ E K + + + +++LVH C+ CR N C SC+
Sbjct: 1751 DEGSSQGEPQSKSPQESRRVSIQRCIQSLVHACQ--CR-----------NANCSLPSCQK 1797
Query: 289 LELLVRHFAGCKLRVPGGCGHCKRMWQLLELHSRLCADPDFCRVPLC 335
++ +V+H GCK + GGC CK++ L H++ C + + C VP C
Sbjct: 1798 MKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQE-NKCPVPFC 1843
>P300_HUMAN (Q09472) E1A-associated protein p300 (EC 2.3.1.48)
Length = 2414
Score = 52.8 bits (125), Expect = 1e-06
Identities = 31/107 (28%), Positives = 52/107 (47%), Gaps = 14/107 (13%)
Query: 229 DEENSKKERIRKMNEREVYLQLYDAMEALVHICRDGCRTIGPHDKDFKANQPCRYTSCKG 288
DE N+++ + L + +++LVH C+ CR N C SC+
Sbjct: 1714 DESNNQQAAATQSPGDSRRLSIQRCIQSLVHACQ--CR-----------NANCSLPSCQK 1760
Query: 289 LELLVRHFAGCKLRVPGGCGHCKRMWQLLELHSRLCADPDFCRVPLC 335
++ +V+H GCK + GGC CK++ L H++ C + + C VP C
Sbjct: 1761 MKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQE-NKCPVPFC 1806
>YLJ8_CAEEL (P34371) Hypothetical protein C50C3.8 in chromosome III
Length = 410
Score = 50.1 bits (118), Expect = 8e-06
Identities = 33/126 (26%), Positives = 64/126 (50%), Gaps = 7/126 (5%)
Query: 109 ISIFGVPHDAVRVFIRYLYSSCYEKEEMKEFVLHLLVLSHVYAVPHLKRECEQKLELGLL 168
I I +D+VR + ++Y+ E E + + +L ++ Y V LK +CE+ + +
Sbjct: 261 IHIEDAKYDSVRAMVEFMYTGATESLESQGNIDEILAIADKYEVLMLKDQCERLIAQTI- 319
Query: 169 TMDNLVDVFQLALLCD---APRLSLICHRKILKNFRTVSESEGWKAMKQSHPVLEKEILE 225
NL +V Q+A+ D A L R + + R V +++ W ++K+S L E+LE
Sbjct: 320 ---NLKNVTQIAMFSDTYTADYLKSAVIRFLTTHHRVVIKTQDWISLKKSRHELANELLE 376
Query: 226 SMIDEE 231
+++ +
Sbjct: 377 AVLSTD 382
>CBP1_CAEEL (P34545) Protein cbp-1
Length = 2056
Score = 46.2 bits (108), Expect = 1e-04
Identities = 28/89 (31%), Positives = 41/89 (45%), Gaps = 14/89 (15%)
Query: 247 YLQLYDAMEALVHICRDGCRTIGPHDKDFKANQPCRYTSCKGLELLVRHFAGCKLRVPGG 306
Y + + +LVH C+ CR CR SC ++ +V+H CK R+ G
Sbjct: 1554 YESIQRCIASLVHACQ--CRDAN-----------CRRMSCHKMKRVVQHTKMCKKRINGT 1600
Query: 307 CGHCKRMWQLLELHSRLCADPDFCRVPLC 335
C CK++ L H++ C D C VP C
Sbjct: 1601 CPVCKQLIALCCYHAKHCT-RDACTVPFC 1628
>BTB9_HUMAN (Q96Q07) BTB/POZ domain containing protein 9
Length = 612
Score = 44.3 bits (103), Expect = 4e-04
Identities = 39/154 (25%), Positives = 73/154 (47%), Gaps = 16/154 (10%)
Query: 117 DAVRVFIRYLYSS-CYEKEEMKEFVLHLLVLSHVYAVPHLKRECEQKLELGLLTMDNLVD 175
+A + ++Y+Y+ +E +E +L L L+H Y P L+ + L +L + N+
Sbjct: 86 EAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYL-CTILNIQNVCM 144
Query: 176 VFQLALLCDAPRLSLICHRKILKNFRTVSESEGWKA----------MKQSHPVLEKEILE 225
F +A L P+L+ +C + +N + V SEG+ + ++ S EK+I
Sbjct: 145 TFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEKDIFL 204
Query: 226 SMID--EENSKKERIRKMNEREVYLQLYDAMEAL 257
++++ + NSK+ M + V L L E L
Sbjct: 205 ALLNWCKHNSKENHAEIM--QAVRLPLMSLTELL 236
>BTB9_MOUSE (Q8C726) BTB/POZ domain containing protein 9
Length = 612
Score = 42.7 bits (99), Expect = 0.001
Identities = 26/100 (26%), Positives = 53/100 (53%), Gaps = 2/100 (2%)
Query: 117 DAVRVFIRYLYSS-CYEKEEMKEFVLHLLVLSHVYAVPHLKRECEQKLELGLLTMDNLVD 175
+A + +RY+Y+ +E +E +L L L+H Y P L+ + L +L + N+
Sbjct: 86 EAFTMLLRYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYL-CTILNIQNVCM 144
Query: 176 VFQLALLCDAPRLSLICHRKILKNFRTVSESEGWKAMKQS 215
F +A L P+L+ +C + +N + V S+G+ ++ ++
Sbjct: 145 TFDVASLYSLPKLTCMCCMFMDRNAQEVLASDGFLSLSKT 184
>YNV5_CAEEL (P34568) Hypothetical protein T16H12.5 in chromosome III
Length = 451
Score = 42.4 bits (98), Expect = 0.002
Identities = 29/115 (25%), Positives = 55/115 (47%), Gaps = 3/115 (2%)
Query: 117 DAVRVFIRYLYSSCYEKEEMKEFVLHLLVLSHVYAVPHLKRECEQKLELGLLTMDNLVDV 176
+ +R + Y+Y+ + + +++ L+ + Y + LK CEQ L LT DN
Sbjct: 320 EVMRELLVYMYTG--QTKYIEQMAQSLIAAADKYQLDRLKVMCEQAL-CYQLTTDNASLT 376
Query: 177 FQLALLCDAPRLSLICHRKILKNFRTVSESEGWKAMKQSHPVLEKEILESMIDEE 231
LA + A +L I N V ++EGW+ + + HP L +E+ ++ ++
Sbjct: 377 LMLADMYSASQLRAHSINFINVNANEVMDTEGWEDLVRDHPKLLEEVFRALATQQ 431
>SPOP_MOUSE (Q6ZWS8) Speckle-type POZ protein (PDX-1 C-terminal
interacting factor 1) (PCIF1)
Length = 374
Score = 40.0 bits (92), Expect = 0.008
Identities = 33/132 (25%), Positives = 58/132 (43%), Gaps = 3/132 (2%)
Query: 96 MLKQANRSNRWRSISIFGVPHDAVRVFIRYLYSSCYEKEEMKEFVLHLLVLSHVYAVPHL 155
M + ++ + I V + + + ++Y+ + + + LL + YA+ L
Sbjct: 228 MFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTG--KAPNLDKMADDLLAAADKYALERL 285
Query: 156 KRECEQKLELGLLTMDNLVDVFQLALLCDAPRLSLICHRKILKNFRTVSESEGWKAMKQS 215
K CE L L+++N ++ LA L A +L I + V E+ GWK+M S
Sbjct: 286 KVMCEDAL-CSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVS 344
Query: 216 HPVLEKEILESM 227
HP L E S+
Sbjct: 345 HPHLVAEAYRSL 356
>SPOP_HUMAN (O43791) Speckle-type POZ protein
Length = 374
Score = 40.0 bits (92), Expect = 0.008
Identities = 33/132 (25%), Positives = 58/132 (43%), Gaps = 3/132 (2%)
Query: 96 MLKQANRSNRWRSISIFGVPHDAVRVFIRYLYSSCYEKEEMKEFVLHLLVLSHVYAVPHL 155
M + ++ + I V + + + ++Y+ + + + LL + YA+ L
Sbjct: 228 MFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTG--KAPNLDKMADDLLAAADKYALERL 285
Query: 156 KRECEQKLELGLLTMDNLVDVFQLALLCDAPRLSLICHRKILKNFRTVSESEGWKAMKQS 215
K CE L L+++N ++ LA L A +L I + V E+ GWK+M S
Sbjct: 286 KVMCEDAL-CSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVS 344
Query: 216 HPVLEKEILESM 227
HP L E S+
Sbjct: 345 HPHLVAEAYRSL 356
>BTB2_HUMAN (Q9BX70) BTB/POZ domain containing protein 2
Length = 525
Score = 38.1 bits (87), Expect = 0.031
Identities = 29/92 (31%), Positives = 44/92 (47%), Gaps = 3/92 (3%)
Query: 118 AVRVFIRYLYSSCYEKEEMKEFVLHLLVLSHVYAVPHLKRECEQKLELGLLTMDNLVDVF 177
A +++LYS E + E V+ L + YAVP L+ C + L+ L DN +
Sbjct: 170 AFLALLKFLYSD--EVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRA-DNAFMLL 226
Query: 178 QLALLCDAPRLSLICHRKILKNFRTVSESEGW 209
A L D P+L+ +C I KN +EG+
Sbjct: 227 TQARLFDEPQLASLCLENIDKNTADAITAEGF 258
>BTB3_MOUSE (P58545) BTB/POZ domain containing protein 3
Length = 532
Score = 35.0 bits (79), Expect = 0.26
Identities = 40/148 (27%), Positives = 60/148 (40%), Gaps = 14/148 (9%)
Query: 109 ISIFGVPHDAVRVFIRYLYSSCYEKEEMKEFVLHLLVLSHVYAVPHLKRECEQKLELGLL 168
I I V A ++Y+Y C E + + VL L + Y VPHL R C LE L
Sbjct: 174 IRIPDVEPAAFLAMLKYIY--CDEIDLAADTVLATLYAAKKYIVPHLARACVNFLETS-L 230
Query: 169 TMDNLVDVFQLALLCDAPRLSLICHRKILKNFRTVSESEGWKAMKQSHPVLEKEILESMI 228
+ N + + L + P L+ C I +SEG+ ++ + LES++
Sbjct: 231 SAKNACVLLSQSCLFEEPDLTQRCWEVIDAQAELALKSEGFCD-------IDFQTLESIL 283
Query: 229 DEENSKKERI----RKMNEREVYLQLYD 252
E + I +N EV Q D
Sbjct: 284 RRETLNAKEIVVFEAALNWAEVECQRQD 311
>BTB3_HUMAN (Q9Y2F9) BTB/POZ domain containing protein 3
Length = 522
Score = 35.0 bits (79), Expect = 0.26
Identities = 40/148 (27%), Positives = 60/148 (40%), Gaps = 14/148 (9%)
Query: 109 ISIFGVPHDAVRVFIRYLYSSCYEKEEMKEFVLHLLVLSHVYAVPHLKRECEQKLELGLL 168
I I V A ++Y+Y C E + + VL L + Y VPHL R C LE L
Sbjct: 164 IRIPDVEPAAFLAMLKYIY--CDEIDLAADTVLATLYAAKKYIVPHLARACVNFLETS-L 220
Query: 169 TMDNLVDVFQLALLCDAPRLSLICHRKILKNFRTVSESEGWKAMKQSHPVLEKEILESMI 228
+ N + + L + P L+ C I +SEG+ ++ + LES++
Sbjct: 221 SAKNACVLLSQSCLFEEPDLTQRCWEVIDAQAELALKSEGFCD-------IDFQTLESIL 273
Query: 229 DEENSKKERI----RKMNEREVYLQLYD 252
E + I +N EV Q D
Sbjct: 274 RRETLNAKEIVVFEAALNWAEVECQRQD 301
>BTB1_HUMAN (Q9H0C5) BTB/POZ domain containing protein 1 (Hepatitis
C virus NS5A-transactivated protein 8) (NS5ATP8)
Length = 482
Score = 35.0 bits (79), Expect = 0.26
Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 3/92 (3%)
Query: 118 AVRVFIRYLYSSCYEKEEMKEFVLHLLVLSHVYAVPHLKRECEQKLELGLLTMDNLVDVF 177
A +R+LYS E + E V+ L + YAVP L+ C + L L DN +
Sbjct: 128 AFLALLRFLYSD--EVQIGPETVMTTLYTAKKYAVPALEAHCVEFLTKHLRA-DNAFMLL 184
Query: 178 QLALLCDAPRLSLICHRKILKNFRTVSESEGW 209
A L D P+L+ +C I K+ +EG+
Sbjct: 185 TQARLFDEPQLASLCLDTIDKSTMDAISAEGF 216
>BTB1_MOUSE (P58544) BTB/POZ domain containing protein 1 (Glucose
signal repressing protein)
Length = 488
Score = 34.3 bits (77), Expect = 0.45
Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 3/92 (3%)
Query: 118 AVRVFIRYLYSSCYEKEEMKEFVLHLLVLSHVYAVPHLKRECEQKLELGLLTMDNLVDVF 177
A +R+LYS E + E V+ L + YAVP L+ C + L L DN +
Sbjct: 134 AFLALLRFLYSD--EVQIGPETVMTTLYTAKKYAVPALEAHCVEFLTKHLRA-DNAFMLL 190
Query: 178 QLALLCDAPRLSLICHRKILKNFRTVSESEGW 209
A L D P+L+ +C I K+ +EG+
Sbjct: 191 TQARLFDEPQLASLCLDTIDKSTVDAISAEGF 222
>PR18_HUMAN (Q99633) Pre-mRNA splicing factor 18 (PRP18 homolog)
(hPRP18)
Length = 342
Score = 33.5 bits (75), Expect = 0.77
Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 5/63 (7%)
Query: 200 FRTVSESEGWKAMKQSHPVLEKEILESMIDEENSKKERIRKMNEREVYLQL-----YDAM 254
++ + E K + S+PVLE E+ E + S++E IR++ ER ++L YDA
Sbjct: 47 YKIQPKEEDQKPLTSSNPVLELELAEEKLPMTLSRQEVIRRLRERGEPIRLFGETDYDAF 106
Query: 255 EAL 257
+ L
Sbjct: 107 QRL 109
>PR18_RAT (Q9JKB8) Pre-mRNA splicing factor 18 (PRP18 homolog)
(Potassium channel regulatory factor)
Length = 342
Score = 32.7 bits (73), Expect = 1.3
Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 5/63 (7%)
Query: 200 FRTVSESEGWKAMKQSHPVLEKEILESMIDEENSKKERIRKMNEREVYLQL-----YDAM 254
++ + + K + S+PVLE E+ E + S++E IR++ ER ++L YDA
Sbjct: 47 YKVQPKEDDQKPLTSSNPVLELELAEEKLPMTLSRQEVIRRLRERGEPMRLFGETDYDAF 106
Query: 255 EAL 257
+ L
Sbjct: 107 QRL 109
>ZY28_HUMAN (Q9HCC9) Zinc finger FYVE domain containing protein 28
Length = 887
Score = 32.3 bits (72), Expect = 1.7
Identities = 24/85 (28%), Positives = 45/85 (52%), Gaps = 10/85 (11%)
Query: 160 EQKLELGLLTMDNLVDVFQLALLCDAPRLSLICHRKI-----LKNFRTVSESEGWKAMKQ 214
E+ L+ G LT D ++D ++ AL+ PRL+++C + L R V + + +
Sbjct: 203 ERALDFGYLTQD-MIDDYEPALMFSIPRLAIVCGLVVYADGPLNLDRKVEDMS--ELFRP 259
Query: 215 SHPVLEK--EILESMIDEENSKKER 237
H +L K ++L+++ +EE ER
Sbjct: 260 FHTLLRKIRDLLQTLTEEELHTLER 284
>PR18_MOUSE (Q8BM39) Pre-mRNA splicing factor 18 (PRP18 homolog)
Length = 342
Score = 32.3 bits (72), Expect = 1.7
Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 5/63 (7%)
Query: 200 FRTVSESEGWKAMKQSHPVLEKEILESMIDEENSKKERIRKMNEREVYLQL-----YDAM 254
++ + + K + S+PVLE E+ E + S++E IR++ ER ++L YDA
Sbjct: 47 YKIQPKEDDQKPLTSSNPVLELELAEEKLPMTLSRQEVIRRLRERGEPIRLFGETDYDAF 106
Query: 255 EAL 257
+ L
Sbjct: 107 QRL 109
>TS13_MOUSE (Q01755) Testis-specific protein PBS13
Length = 566
Score = 32.0 bits (71), Expect = 2.2
Identities = 24/99 (24%), Positives = 50/99 (50%), Gaps = 6/99 (6%)
Query: 165 LGLLTMDNLVDVFQLALLCDAPRLSLICHRK----ILKNFRTVSESEGWKAMKQSHPVLE 220
L LLT D + F L+ D PRL + ++ IL + V+ S + S ++
Sbjct: 360 LNLLTWDPENEEFPETLVADRPRLQELESQQSQLTILASVLLVASSFSDSGLFSSPQFVD 419
Query: 221 K--EILESMIDEENSKKERIRKMNEREVYLQLYDAMEAL 257
K +I +S++++ NS+ E + + +V +++ +E++
Sbjct: 420 KLKQITKSLVEDFNSRPEEVMQSVSEQVVEEVHQGLESM 458
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.342 0.149 0.512
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,201,680
Number of Sequences: 164201
Number of extensions: 1402978
Number of successful extensions: 5587
Number of sequences better than 10.0: 34
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 5568
Number of HSP's gapped (non-prelim): 36
length of query: 335
length of database: 59,974,054
effective HSP length: 111
effective length of query: 224
effective length of database: 41,747,743
effective search space: 9351494432
effective search space used: 9351494432
T: 11
A: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 39 (22.0 bits)
S2: 66 (30.0 bits)
Medicago: description of AC146856.6