BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC146819.3 + phase: 0 
         (380 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

ADHX_PEA (P80572) Alcohol dehydrogenase class III (EC 1.1.1.1) (...   737  0.0
ADHX_ORYSA (P93436) Alcohol dehydrogenase class III (EC 1.1.1.1)...   712  0.0
ADHX_MAIZE (P93629) Alcohol dehydrogenase class III (EC 1.1.1.1)...   701  0.0
ADHX_ARATH (Q96533) Alcohol dehydrogenase class III (EC 1.1.1.1)...   699  0.0
ADHX_SPAAU (P79896) Alcohol dehydrogenase class III (EC 1.1.1.1)...   540  e-153
ADHX_RAT (P12711) Alcohol dehydrogenase class III (EC 1.1.1.1) (...   530  e-150
ADHH_GADMO (P81600) Alcohol dehydrogenase class III H chain (EC ...   527  e-149
ADHX_HUMAN (P11766) Alcohol dehydrogenase class III chi chain (E...   526  e-149
ADHX_MOUSE (P28474) Alcohol dehydrogenase class III (EC 1.1.1.1)...   525  e-149
ADHX_HORSE (P19854) Alcohol dehydrogenase class III chain (EC 1....   521  e-147
ADHX_UROHA (P80467) Alcohol dehydrogenase class III (EC 1.1.1.1)...   520  e-147
ADHX_DROME (P46415) Alcohol dehydrogenase class III (EC 1.1.1.1)...   517  e-146
ADHL_GADMO (P81601) Alcohol dehydrogenase class III L chain (EC ...   516  e-146
ADHX_RABIT (O19053) Alcohol dehydrogenase class III chain (EC 1....   515  e-146
ADHX_OCTVU (P81431) Alcohol dehydrogenase class III (EC 1.1.1.1)...   508  e-144
ADHX_MYXGL (P80360) Alcohol dehydrogenase class III (EC 1.1.1.1)...   492  e-139
ADH3_ECOLI (P25437) Alcohol dehydrogenase class III (EC 1.1.1.1)...   485  e-137
ADH_FRAAN (P17648) Alcohol dehydrogenase (EC 1.1.1.1)                 482  e-136
ADHX_CAEEL (Q17335) Alcohol dehydrogenase class III (EC 1.1.1.1)...   482  e-136
ADH3_SYNY3 (P73138) Probable alcohol dehydrogenase class III (EC...   482  e-136

>ADHX_PEA (P80572) Alcohol dehydrogenase class III (EC 1.1.1.1)
           (Glutathione-dependent formaldehyde dehydrogenase) (EC
           1.2.1.1) (FDH) (FALDH) (GSH-FDH)
          Length = 378

 Score =  737 bits (1902), Expect = 0.0
 Identities = 356/377 (94%), Positives = 367/377 (96%)

Query: 4   STEGQVITCKAAVAWEPNKPLTIEDVEVAPPQANEVRIQILFTALCHTDAYTWSGKDPEG 63
           +T+GQVITCKAAVAWEPNKPLTIEDVEVAPPQANEVRIQILFTALCHTDAYT  GKDPEG
Sbjct: 1   ATQGQVITCKAAVAWEPNKPLTIEDVEVAPPQANEVRIQILFTALCHTDAYTLGGKDPEG 60

Query: 64  LFPCILGHEAAGIVESVGEGVTDVKPGDHVIPCYQAECGECKFCKSGKTNLCGKVRAATG 123
           LFPCILGHEAAGIVESVGEGVTDVKPGDHVIP YQAECGECKFCKS KTNLCGKVRAATG
Sbjct: 61  LFPCILGHEAAGIVESVGEGVTDVKPGDHVIPSYQAECGECKFCKSPKTNLCGKVRAATG 120

Query: 124 VGVMMNDRKPRFSIKGKPIYHFMGTSTFSQYTVVHDVSVAKIHPDAALDKVCLLGCGVPT 183
           VGVMM DRK RFS+KGKPIYHFMGTSTFSQYTVVHDVSVAKIHPDA LDKVCLLGCGVPT
Sbjct: 121 VGVMMADRKSRFSVKGKPIYHFMGTSTFSQYTVVHDVSVAKIHPDAPLDKVCLLGCGVPT 180

Query: 184 GLGAVWNTAKVEPGSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDSNKFDTAKNFGVT 243
           GLGAVWNTAKVEPGSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDSNK+DTAKNFGVT
Sbjct: 181 GLGAVWNTAKVEPGSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDSNKYDTAKNFGVT 240

Query: 244 EFINPKDHEKPIQQVISDLTDGGVDYSFECIGNVSVMRSALECTHKGWGTSVVVGVAASG 303
           EFINPKDHEKPIQQVI DLTDGGVDYSFEC+GNVSVMRSALEC HKGWGTSV+VGVAASG
Sbjct: 241 EFINPKDHEKPIQQVIIDLTDGGVDYSFECLGNVSVMRSALECCHKGWGTSVIVGVAASG 300

Query: 304 QEISTRPFQLVTGRVWKGTAFGGFKSRSQVPWLVEKYLKKEIKVDEYVTHNLTLAEINEA 363
           QEISTRPFQLVTGRVWKGTAFGGFKSRSQVPWLVEKYLKKEIKVDEY+THNLTL EIN+A
Sbjct: 301 QEISTRPFQLVTGRVWKGTAFGGFKSRSQVPWLVEKYLKKEIKVDEYITHNLTLLEINKA 360

Query: 364 FDLMHEGKCLRCVLALH 380
           FDL+HEG+CLRCVLA+H
Sbjct: 361 FDLLHEGQCLRCVLAVH 377


>ADHX_ORYSA (P93436) Alcohol dehydrogenase class III (EC 1.1.1.1)
           (Glutathione-dependent formaldehyde dehydrogenase) (EC
           1.2.1.1) (FDH) (FALDH) (GSH-FDH)
          Length = 381

 Score =  712 bits (1838), Expect = 0.0
 Identities = 343/378 (90%), Positives = 359/378 (94%)

Query: 1   MASSTEGQVITCKAAVAWEPNKPLTIEDVEVAPPQANEVRIQILFTALCHTDAYTWSGKD 60
           MASST+GQVITCKAAVAWE NKP+TIEDV+VAPPQA EVR++ILFTA CHTD YTWSGKD
Sbjct: 1   MASSTQGQVITCKAAVAWEANKPMTIEDVQVAPPQAGEVRVKILFTAFCHTDHYTWSGKD 60

Query: 61  PEGLFPCILGHEAAGIVESVGEGVTDVKPGDHVIPCYQAECGECKFCKSGKTNLCGKVRA 120
           PEGLFPCILGHEAAGIVESVGEGVT+V+PGDHVIPCYQAEC ECKFCKSGKTNLCGKVRA
Sbjct: 61  PEGLFPCILGHEAAGIVESVGEGVTEVQPGDHVIPCYQAECRECKFCKSGKTNLCGKVRA 120

Query: 121 ATGVGVMMNDRKPRFSIKGKPIYHFMGTSTFSQYTVVHDVSVAKIHPDAALDKVCLLGCG 180
           ATGVGVMMNDRK RFSI GKPIYHFMGTSTFSQYTVVHDVSVAKI+P A LDKVCLLGCG
Sbjct: 121 ATGVGVMMNDRKSRFSINGKPIYHFMGTSTFSQYTVVHDVSVAKINPQAPLDKVCLLGCG 180

Query: 181 VPTGLGAVWNTAKVEPGSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDSNKFDTAKNF 240
           V TGLGAVWNTAKVE GSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDS KFD AKNF
Sbjct: 181 VSTGLGAVWNTAKVEAGSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDSKKFDVAKNF 240

Query: 241 GVTEFINPKDHEKPIQQVISDLTDGGVDYSFECIGNVSVMRSALECTHKGWGTSVVVGVA 300
           GVTEF+NPKDH+KPIQQVI DLTDGGVDYSFECIGNVSVMRSALEC HKGWGTSV+VGVA
Sbjct: 241 GVTEFVNPKDHDKPIQQVIVDLTDGGVDYSFECIGNVSVMRSALECCHKGWGTSVIVGVA 300

Query: 301 ASGQEISTRPFQLVTGRVWKGTAFGGFKSRSQVPWLVEKYLKKEIKVDEYVTHNLTLAEI 360
           ASGQEISTRPFQLVTGRVWKGTAFGGFKSRSQVPWLVEKYL KEIKVDEYVTH++ L +I
Sbjct: 301 ASGQEISTRPFQLVTGRVWKGTAFGGFKSRSQVPWLVEKYLNKEIKVDEYVTHSMNLTDI 360

Query: 361 NEAFDLMHEGKCLRCVLA 378
           N+AFDL+HEG CLRCVLA
Sbjct: 361 NKAFDLLHEGGCLRCVLA 378


>ADHX_MAIZE (P93629) Alcohol dehydrogenase class III (EC 1.1.1.1)
           (Glutathione-dependent formaldehyde dehydrogenase) (EC
           1.2.1.1) (FDH) (FALDH) (GSH-FDH)
          Length = 381

 Score =  701 bits (1810), Expect = 0.0
 Identities = 330/379 (87%), Positives = 361/379 (95%)

Query: 1   MASSTEGQVITCKAAVAWEPNKPLTIEDVEVAPPQANEVRIQILFTALCHTDAYTWSGKD 60
           MAS T+GQVITCKAAVA+EPNKPL IEDV+VAPPQA EVR++ILFTALCHTD YTWSGKD
Sbjct: 1   MASPTQGQVITCKAAVAYEPNKPLVIEDVQVAPPQAGEVRVKILFTALCHTDHYTWSGKD 60

Query: 61  PEGLFPCILGHEAAGIVESVGEGVTDVKPGDHVIPCYQAECGECKFCKSGKTNLCGKVRA 120
           PEGLFPCILGHEAAGIVESVGEGVTDV+PGDHVIPCYQAEC ECKFCKSGKTNLCGKVR+
Sbjct: 61  PEGLFPCILGHEAAGIVESVGEGVTDVQPGDHVIPCYQAECKECKFCKSGKTNLCGKVRS 120

Query: 121 ATGVGVMMNDRKPRFSIKGKPIYHFMGTSTFSQYTVVHDVSVAKIHPDAALDKVCLLGCG 180
           ATGVGVMMND K RFS+ GKPIYHFMGTSTFSQYTVVHDVSVAKI+P A LDKVCLLGCG
Sbjct: 121 ATGVGVMMNDMKSRFSVNGKPIYHFMGTSTFSQYTVVHDVSVAKINPQAPLDKVCLLGCG 180

Query: 181 VPTGLGAVWNTAKVEPGSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDSNKFDTAKNF 240
           VPTGLGAVWNTAKVE GS+VA+FGLGTVGLAVAEGAK+AGASR+IGIDID+ KFD AKNF
Sbjct: 181 VPTGLGAVWNTAKVESGSVVAVFGLGTVGLAVAEGAKAAGASRVIGIDIDNKKFDVAKNF 240

Query: 241 GVTEFINPKDHEKPIQQVISDLTDGGVDYSFECIGNVSVMRSALECTHKGWGTSVVVGVA 300
           GVTEF+NPK+H+KPIQQV+ DLTDGGVDYSFECIGNVS+MR+ALEC+ KGWGTSV+VGVA
Sbjct: 241 GVTEFVNPKEHDKPIQQVLVDLTDGGVDYSFECIGNVSIMRAALECSDKGWGTSVIVGVA 300

Query: 301 ASGQEISTRPFQLVTGRVWKGTAFGGFKSRSQVPWLVEKYLKKEIKVDEYVTHNLTLAEI 360
           ASGQEISTRPFQLVTGRVWKGTAFGGFKSR+QVPWLV+KY+KKEIKVDEY+THN+ LA+I
Sbjct: 301 ASGQEISTRPFQLVTGRVWKGTAFGGFKSRTQVPWLVDKYMKKEIKVDEYITHNMNLADI 360

Query: 361 NEAFDLMHEGKCLRCVLAL 379
           N+AF L+HEG CLRCVLA+
Sbjct: 361 NDAFHLLHEGGCLRCVLAM 379


>ADHX_ARATH (Q96533) Alcohol dehydrogenase class III (EC 1.1.1.1)
           (Glutathione-dependent formaldehyde dehydrogenase) (EC
           1.2.1.1) (FDH) (FALDH) (GSH-FDH)
          Length = 379

 Score =  699 bits (1803), Expect = 0.0
 Identities = 332/374 (88%), Positives = 356/374 (94%)

Query: 4   STEGQVITCKAAVAWEPNKPLTIEDVEVAPPQANEVRIQILFTALCHTDAYTWSGKDPEG 63
           +T+GQVITCKAAVA+EPNKPL IEDV+VAPPQA EVRI+IL+TALCHTDAYTWSGKDPEG
Sbjct: 2   ATQGQVITCKAAVAYEPNKPLVIEDVQVAPPQAGEVRIKILYTALCHTDAYTWSGKDPEG 61

Query: 64  LFPCILGHEAAGIVESVGEGVTDVKPGDHVIPCYQAECGECKFCKSGKTNLCGKVRAATG 123
           LFPCILGHEAAGIVESVGEGVT+V+ GDHVIPCYQAEC ECKFCKSGKTNLCGKVR+ATG
Sbjct: 62  LFPCILGHEAAGIVESVGEGVTEVQAGDHVIPCYQAECRECKFCKSGKTNLCGKVRSATG 121

Query: 124 VGVMMNDRKPRFSIKGKPIYHFMGTSTFSQYTVVHDVSVAKIHPDAALDKVCLLGCGVPT 183
           VG+MMNDRK RFS+ GKPIYHFMGTSTFSQYTVVHDVSVAKI P A LDKVCLLGCGVPT
Sbjct: 122 VGIMMNDRKSRFSVNGKPIYHFMGTSTFSQYTVVHDVSVAKIDPTAPLDKVCLLGCGVPT 181

Query: 184 GLGAVWNTAKVEPGSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDSNKFDTAKNFGVT 243
           GLGAVWNTAKVEPGS VAIFGLGTVGLAVAEGAK+AGASRIIGIDIDS K++TAK FGV 
Sbjct: 182 GLGAVWNTAKVEPGSNVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETAKKFGVN 241

Query: 244 EFINPKDHEKPIQQVISDLTDGGVDYSFECIGNVSVMRSALECTHKGWGTSVVVGVAASG 303
           EF+NPKDH+KPIQ+VI DLTDGGVDYSFECIGNVSVMR+ALEC HKGWGTSV+VGVAASG
Sbjct: 242 EFVNPKDHDKPIQEVIVDLTDGGVDYSFECIGNVSVMRAALECCHKGWGTSVIVGVAASG 301

Query: 304 QEISTRPFQLVTGRVWKGTAFGGFKSRSQVPWLVEKYLKKEIKVDEYVTHNLTLAEINEA 363
           QEISTRPFQLVTGRVWKGTAFGGFKSR+QVPWLVEKY+ KEIKVDEY+THNLTL EIN+A
Sbjct: 302 QEISTRPFQLVTGRVWKGTAFGGFKSRTQVPWLVEKYMNKEIKVDEYITHNLTLGEINKA 361

Query: 364 FDLMHEGKCLRCVL 377
           FDL+HEG CLRCVL
Sbjct: 362 FDLLHEGTCLRCVL 375


>ADHX_SPAAU (P79896) Alcohol dehydrogenase class III (EC 1.1.1.1)
           (Glutathione-dependent formaldehyde dehydrogenase) (EC
           1.2.1.1) (FDH) (FALDH)
          Length = 376

 Score =  540 bits (1391), Expect = e-153
 Identities = 257/373 (68%), Positives = 303/373 (80%), Gaps = 1/373 (0%)

Query: 5   TEGQVITCKAAVAWEPNKPLTIEDVEVAPPQANEVRIQILFTALCHTDAYTWSGKDPEGL 64
           T G+VI CKAAVAWEP KPL+IE+VEVAPP A+EVRI++  T +CHTDAYT SG DPEGL
Sbjct: 3   TAGKVIKCKAAVAWEPGKPLSIEEVEVAPPNAHEVRIKLFATGVCHTDAYTLSGSDPEGL 62

Query: 65  FPCILGHEAAGIVESVGEGVTDVKPGDHVIPCYQAECGECKFCKSGKTNLCGKVRAATGV 124
           FP ILGHE AG VESVGEGVT  KPGD VIP Y  +CGECKFCK+ KTNLC K+R   G 
Sbjct: 63  FPVILGHEGAGTVESVGEGVTKFKPGDTVIPLYVPQCGECKFCKNPKTNLCQKIRITQGQ 122

Query: 125 GVMMNDRKPRFSIKGKPIYHFMGTSTFSQYTVVHDVSVAKIHPDAALDKVCLLGCGVPTG 184
           G ++ D+  RF+ KGK ++HFMGTSTFS+YTVV D+S+AK++  A +DKVCLLGCG+ TG
Sbjct: 123 G-LLPDKTSRFTCKGKQVFHFMGTSTFSEYTVVADISLAKVNEKAPMDKVCLLGCGISTG 181

Query: 185 LGAVWNTAKVEPGSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDSNKFDTAKNFGVTE 244
            GA  NTAKVEPGS  A+FGLG VGLAV  G K AGA+RIIGID++  KF+TAK FG TE
Sbjct: 182 YGAALNTAKVEPGSTCAVFGLGAVGLAVIMGCKVAGATRIIGIDLNPAKFETAKEFGATE 241

Query: 245 FINPKDHEKPIQQVISDLTDGGVDYSFECIGNVSVMRSALECTHKGWGTSVVVGVAASGQ 304
           F+NPKDH KPIQ+V+ ++TDGGVDYSFECIGNV +MR+ALE  HKGWG SV++GVA +GQ
Sbjct: 242 FVNPKDHSKPIQEVLVEMTDGGVDYSFECIGNVQIMRAALEACHKGWGESVIIGVAGAGQ 301

Query: 305 EISTRPFQLVTGRVWKGTAFGGFKSRSQVPWLVEKYLKKEIKVDEYVTHNLTLAEINEAF 364
           EISTRPFQLVTGRVWKGTAFGG+KS   VP LVE Y+ K++KVDE+VTH L   +INE F
Sbjct: 302 EISTRPFQLVTGRVWKGTAFGGWKSVESVPKLVEDYMSKKLKVDEFVTHTLPFEKINEGF 361

Query: 365 DLMHEGKCLRCVL 377
           +LMH GK +R VL
Sbjct: 362 ELMHAGKSIRTVL 374


>ADHX_RAT (P12711) Alcohol dehydrogenase class III (EC 1.1.1.1)
           (Alcohol dehydrogenase 2) (Glutathione-dependent
           formaldehyde dehydrogenase) (EC 1.2.1.1) (FDH) (FALDH)
           (Alcohol dehydrogenase-B2)
          Length = 373

 Score =  530 bits (1364), Expect = e-150
 Identities = 264/372 (70%), Positives = 299/372 (79%), Gaps = 1/372 (0%)

Query: 8   QVITCKAAVAWEPNKPLTIEDVEVAPPQANEVRIQILFTALCHTDAYTWSGKDPEGLFPC 67
           QVI CKAAVAWE  KPL+IE++EVAPPQA+EVRI+I+ TA+CHTDAYT SG DPEG FP 
Sbjct: 3   QVIRCKAAVAWEAGKPLSIEEIEVAPPQAHEVRIKIIATAVCHTDAYTLSGADPEGCFPV 62

Query: 68  ILGHEAAGIVESVGEGVTDVKPGDHVIPCYQAECGECKFCKSGKTNLCGKVRAATGVGVM 127
           ILGHE AGIVESVGEGVT +K GD VIP Y  +CGECKFC + KTNLC K+R   G G +
Sbjct: 63  ILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKG-L 121

Query: 128 MNDRKPRFSIKGKPIYHFMGTSTFSQYTVVHDVSVAKIHPDAALDKVCLLGCGVPTGLGA 187
           M D   RF+ KGKPI HFMGTSTFS+YTVV D+SVAKI P A LDKVCLLGCG+ TG GA
Sbjct: 122 MPDGTSRFTCKGKPILHFMGTSTFSEYTVVADISVAKIDPSAPLDKVCLLGCGISTGYGA 181

Query: 188 VWNTAKVEPGSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDSNKFDTAKNFGVTEFIN 247
             NTAKVEPGS  A+FGLG VGLAV  G K AGASRIIGIDI+ +KF  AK FG TE IN
Sbjct: 182 AVNTAKVEPGSTCAVFGLGGVGLAVIMGCKVAGASRIIGIDINKDKFAKAKEFGATECIN 241

Query: 248 PKDHEKPIQQVISDLTDGGVDYSFECIGNVSVMRSALECTHKGWGTSVVVGVAASGQEIS 307
           P+D  K IQ+V+ ++TDGGVD+SFECIGNV VMRSALE  HKGWG SVVVGVAASG+EIS
Sbjct: 242 PQDFSKSIQEVLIEMTDGGVDFSFECIGNVKVMRSALEAAHKGWGVSVVVGVAASGEEIS 301

Query: 308 TRPFQLVTGRVWKGTAFGGFKSRSQVPWLVEKYLKKEIKVDEYVTHNLTLAEINEAFDLM 367
           TRPFQLVTGR WKGTAFGG+KS   VP LV +Y+ K+IKVDE+VT NL+  +IN+AFDLM
Sbjct: 302 TRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTGNLSFDQINKAFDLM 361

Query: 368 HEGKCLRCVLAL 379
           H G  +R VL L
Sbjct: 362 HSGNSIRTVLKL 373


>ADHH_GADMO (P81600) Alcohol dehydrogenase class III H chain (EC
           1.1.1.1) (Glutathione-dependent formaldehyde
           dehydrogenase) (EC 1.2.1.1) (FDH)
          Length = 375

 Score =  527 bits (1357), Expect = e-149
 Identities = 251/374 (67%), Positives = 295/374 (78%), Gaps = 1/374 (0%)

Query: 4   STEGQVITCKAAVAWEPNKPLTIEDVEVAPPQANEVRIQILFTALCHTDAYTWSGKDPEG 63
           +T GQVI CKAAVAWE  KPL++E+VEVAPP+A EVRI+++ T +CHTDAYT SG DPEG
Sbjct: 1   ATAGQVIKCKAAVAWEAGKPLSLEEVEVAPPRAGEVRIKVVATGVCHTDAYTLSGSDPEG 60

Query: 64  LFPCILGHEAAGIVESVGEGVTDVKPGDHVIPCYQAECGECKFCKSGKTNLCGKVRAATG 123
            FP ILGHE AG+VESVGEGVT  K GD VIP Y  +CGECKFCK+ KTNLC K+R   G
Sbjct: 61  AFPVILGHEGAGLVESVGEGVTKFKAGDTVIPLYVPQCGECKFCKNPKTNLCQKIRVTQG 120

Query: 124 VGVMMNDRKPRFSIKGKPIYHFMGTSTFSQYTVVHDVSVAKIHPDAALDKVCLLGCGVPT 183
            G +M D   RF+ KGK ++HFMGTSTFS+YTVV D+S+A + P A LDKVCLLGCG+ T
Sbjct: 121 RG-LMPDNTSRFTCKGKQLFHFMGTSTFSEYTVVADISLANVDPKAPLDKVCLLGCGIST 179

Query: 184 GLGAVWNTAKVEPGSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDSNKFDTAKNFGVT 243
           G GA  NTAKVEPGS  A+FGLG VGLA   G K AGA+RIIG+DI+  KF  A  FG T
Sbjct: 180 GYGAALNTAKVEPGSTCAVFGLGAVGLAAIMGCKVAGATRIIGVDINPEKFGKAAEFGAT 239

Query: 244 EFINPKDHEKPIQQVISDLTDGGVDYSFECIGNVSVMRSALECTHKGWGTSVVVGVAASG 303
           E +NPKDH +P+Q+V+ ++TDGGVDYSFECIGNV +MRSALE  HKGWG SV++GVA +G
Sbjct: 240 ECLNPKDHARPVQEVLVEMTDGGVDYSFECIGNVEIMRSALEACHKGWGESVIIGVAGAG 299

Query: 304 QEISTRPFQLVTGRVWKGTAFGGFKSRSQVPWLVEKYLKKEIKVDEYVTHNLTLAEINEA 363
           QEI+TRPFQLVTGRVWK TAFGG+KS   VP LVE Y+ K++KVDE+VTH L    INE 
Sbjct: 300 QEIATRPFQLVTGRVWKATAFGGWKSVESVPKLVEDYMNKKLKVDEFVTHTLPFDSINEG 359

Query: 364 FDLMHEGKCLRCVL 377
           FDLMH GK +RCVL
Sbjct: 360 FDLMHAGKSIRCVL 373


>ADHX_HUMAN (P11766) Alcohol dehydrogenase class III chi chain (EC
           1.1.1.1) (Glutathione-dependent formaldehyde
           dehydrogenase) (EC 1.2.1.1) (FDH)
          Length = 373

 Score =  526 bits (1356), Expect = e-149
 Identities = 258/372 (69%), Positives = 302/372 (80%), Gaps = 1/372 (0%)

Query: 8   QVITCKAAVAWEPNKPLTIEDVEVAPPQANEVRIQILFTALCHTDAYTWSGKDPEGLFPC 67
           +VI CKAAVAWE  KPL+IE++EVAPP+A+EVRI+I+ TA+CHTDAYT SG DPEG FP 
Sbjct: 3   EVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGCFPV 62

Query: 68  ILGHEAAGIVESVGEGVTDVKPGDHVIPCYQAECGECKFCKSGKTNLCGKVRAATGVGVM 127
           ILGHE AGIVESVGEGVT +K GD VIP Y  +CGECKFC + KTNLC K+R   G G +
Sbjct: 63  ILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKG-L 121

Query: 128 MNDRKPRFSIKGKPIYHFMGTSTFSQYTVVHDVSVAKIHPDAALDKVCLLGCGVPTGLGA 187
           M D   RF+ KGK I H+MGTSTFS+YTVV D+SVAKI P A LDKVCLLGCG+ TG GA
Sbjct: 122 MPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYGA 181

Query: 188 VWNTAKVEPGSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDSNKFDTAKNFGVTEFIN 247
             NTAK+EPGS+ A+FGLG VGLAV  G K AGASRIIG+DI+ +KF  AK FG TE IN
Sbjct: 182 AVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECIN 241

Query: 248 PKDHEKPIQQVISDLTDGGVDYSFECIGNVSVMRSALECTHKGWGTSVVVGVAASGQEIS 307
           P+D  KPIQ+V+ ++TDGGVDYSFECIGNV VMR+ALE  HKGWG SVVVGVAASG+EI+
Sbjct: 242 PQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEEIA 301

Query: 308 TRPFQLVTGRVWKGTAFGGFKSRSQVPWLVEKYLKKEIKVDEYVTHNLTLAEINEAFDLM 367
           TRPFQLVTGR WKGTAFGG+KS   VP LV +Y+ K+IKVDE+VTHNL+  EIN+AF+LM
Sbjct: 302 TRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFELM 361

Query: 368 HEGKCLRCVLAL 379
           H GK +R V+ +
Sbjct: 362 HSGKSIRTVVKI 373


>ADHX_MOUSE (P28474) Alcohol dehydrogenase class III (EC 1.1.1.1)
           (Alcohol dehydrogenase 2) (Glutathione-dependent
           formaldehyde dehydrogenase) (EC 1.2.1.1) (FDH) (FALDH)
           (Alcohol dehydrogenase-B2) (ADH-B2)
          Length = 373

 Score =  525 bits (1353), Expect = e-149
 Identities = 260/372 (69%), Positives = 300/372 (79%), Gaps = 1/372 (0%)

Query: 8   QVITCKAAVAWEPNKPLTIEDVEVAPPQANEVRIQILFTALCHTDAYTWSGKDPEGLFPC 67
           QVI CKAAVAWE  KPL+IE++EVAPP+A+EVRI+IL TA+CHTDAYT SG+DPEG FP 
Sbjct: 3   QVIRCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKILATAVCHTDAYTLSGRDPEGCFPV 62

Query: 68  ILGHEAAGIVESVGEGVTDVKPGDHVIPCYQAECGECKFCKSGKTNLCGKVRAATGVGVM 127
           ILGHE AGIVESVGEGVT +K GD VIP Y  +CGECKFC + KTNLC K+R   G G +
Sbjct: 63  ILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKG-L 121

Query: 128 MNDRKPRFSIKGKPIYHFMGTSTFSQYTVVHDVSVAKIHPDAALDKVCLLGCGVPTGLGA 187
           M D   RF+ KGK ++HFMGTSTFS+YTVV D+SVAKI P A LDKVCLLGCG+ TG GA
Sbjct: 122 MPDGTSRFTCKGKSVFHFMGTSTFSEYTVVADISVAKIDPSAPLDKVCLLGCGISTGYGA 181

Query: 188 VWNTAKVEPGSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDSNKFDTAKNFGVTEFIN 247
             NTAKVEPGS  A+FGLG VGLAV  G K AGASRIIGIDI+ +KF  AK FG +E I+
Sbjct: 182 AVNTAKVEPGSTCAVFGLGGVGLAVIMGCKVAGASRIIGIDINKDKFAKAKEFGASECIS 241

Query: 248 PKDHEKPIQQVISDLTDGGVDYSFECIGNVSVMRSALECTHKGWGTSVVVGVAASGQEIS 307
           P+D  K IQ+V+ ++TDGGVDYSFECIGNV VMRSALE  HKGWG SVVVGVAASG+EIS
Sbjct: 242 PQDFSKSIQEVLVEMTDGGVDYSFECIGNVKVMRSALEAAHKGWGVSVVVGVAASGEEIS 301

Query: 308 TRPFQLVTGRVWKGTAFGGFKSRSQVPWLVEKYLKKEIKVDEYVTHNLTLAEINEAFDLM 367
           TRPFQLVTGR WKGTAFGG+KS   VP LV +Y+ K+IKVDE+VT NL+  +IN+AFDLM
Sbjct: 302 TRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTGNLSFDQINQAFDLM 361

Query: 368 HEGKCLRCVLAL 379
           H G  +R VL +
Sbjct: 362 HSGDSIRTVLKM 373


>ADHX_HORSE (P19854) Alcohol dehydrogenase class III chain (EC
           1.1.1.1) (Glutathione-dependent formaldehyde
           dehydrogenase) (EC 1.2.1.1) (FDH) (FALDH)
          Length = 373

 Score =  521 bits (1342), Expect = e-147
 Identities = 258/372 (69%), Positives = 301/372 (80%), Gaps = 1/372 (0%)

Query: 8   QVITCKAAVAWEPNKPLTIEDVEVAPPQANEVRIQILFTALCHTDAYTWSGKDPEGLFPC 67
           +VI CKAAVAWE  KP++IE+VEVAPP+A+EVRI+I+ TA+CHTDAYT SG DPEG FP 
Sbjct: 3   EVIKCKAAVAWEAGKPVSIEEVEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGSFPV 62

Query: 68  ILGHEAAGIVESVGEGVTDVKPGDHVIPCYQAECGECKFCKSGKTNLCGKVRAATGVGVM 127
           ILGHE AGIVESVGEGVT +K GD VIP Y  +CGECKFC + +TNLC K+R   G G +
Sbjct: 63  ILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPQTNLCQKIRTTQGKG-L 121

Query: 128 MNDRKPRFSIKGKPIYHFMGTSTFSQYTVVHDVSVAKIHPDAALDKVCLLGCGVPTGLGA 187
           M D   RF+ KGK I H+MGTSTFS+YTVV D+SVAKI P A LDKVCLLGCGV TG GA
Sbjct: 122 MPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGVSTGYGA 181

Query: 188 VWNTAKVEPGSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDSNKFDTAKNFGVTEFIN 247
             NTAKVEPGS  AIFGLG VGLAV  G K AGASRIIG+DI+ +KF  AK FG +E IN
Sbjct: 182 AVNTAKVEPGSTCAIFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFAKAKEFGASECIN 241

Query: 248 PKDHEKPIQQVISDLTDGGVDYSFECIGNVSVMRSALECTHKGWGTSVVVGVAASGQEIS 307
           P+D  KPIQ+V+ ++TDGGVDYSFECIGNV VMR+ALE  HKGWG SVVVGVAASG+EI+
Sbjct: 242 PQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEEIA 301

Query: 308 TRPFQLVTGRVWKGTAFGGFKSRSQVPWLVEKYLKKEIKVDEYVTHNLTLAEINEAFDLM 367
           TRPFQLVTGR WKGTAFGG+KS   +P LV +Y+ K+IKVDE+VTH+L+  +INEAF+LM
Sbjct: 302 TRPFQLVTGRTWKGTAFGGWKSVESIPKLVSEYMSKKIKVDEFVTHSLSFDQINEAFELM 361

Query: 368 HEGKCLRCVLAL 379
           H GK +R V+ L
Sbjct: 362 HAGKSIRTVVKL 373


>ADHX_UROHA (P80467) Alcohol dehydrogenase class III (EC 1.1.1.1)
           (Glutathione-dependent formaldehyde dehydrogenase) (EC
           1.2.1.1) (FDH)
          Length = 373

 Score =  520 bits (1340), Expect = e-147
 Identities = 255/369 (69%), Positives = 297/369 (80%), Gaps = 1/369 (0%)

Query: 9   VITCKAAVAWEPNKPLTIEDVEVAPPQANEVRIQILFTALCHTDAYTWSGKDPEGLFPCI 68
           VI CKAAVAWE  KPL+IE++EVAPP+A+EVR++I+ TA+CHTDAYT SG DPEG FP I
Sbjct: 4   VIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRVKIIATAVCHTDAYTLSGADPEGSFPVI 63

Query: 69  LGHEAAGIVESVGEGVTDVKPGDHVIPCYQAECGECKFCKSGKTNLCGKVRAATGVGVMM 128
           LGHE AGIVESVGEGVT  KPGD VIP Y  +CGECKFC + KTNLC K+R   G GVM 
Sbjct: 64  LGHEGAGIVESVGEGVTKFKPGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKGVMP 123

Query: 129 NDRKPRFSIKGKPIYHFMGTSTFSQYTVVHDVSVAKIHPDAALDKVCLLGCGVPTGLGAV 188
            D   RF+ KGK + HFMGTSTFS+YTVV D+S+ KI+  A LDKVCLLGCGV TG GA 
Sbjct: 124 -DGTSRFTCKGKQVLHFMGTSTFSEYTVVADISLTKINASAPLDKVCLLGCGVSTGYGAA 182

Query: 189 WNTAKVEPGSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDSNKFDTAKNFGVTEFINP 248
            NTAKVEPGS  A+FGLG VGLAV  G K AGASRIIGID++ +KF  AK FG TE I+P
Sbjct: 183 LNTAKVEPGSTCAVFGLGGVGLAVIMGCKVAGASRIIGIDLNKDKFAKAKEFGATECISP 242

Query: 249 KDHEKPIQQVISDLTDGGVDYSFECIGNVSVMRSALECTHKGWGTSVVVGVAASGQEIST 308
            D +KPIQ+V+ ++TDGGVDYSFECIGNV VMR+ALE  HKGWG SV+VGVAA+GQEI+T
Sbjct: 243 ADFKKPIQEVLIEMTDGGVDYSFECIGNVGVMRAALEACHKGWGVSVIVGVAAAGQEIAT 302

Query: 309 RPFQLVTGRVWKGTAFGGFKSRSQVPWLVEKYLKKEIKVDEYVTHNLTLAEINEAFDLMH 368
           RPFQLVTGR WKGTAFGG+KS   VP LV++Y+ K++KVDE+VTH L   +INEAF+LMH
Sbjct: 303 RPFQLVTGRTWKGTAFGGWKSVESVPKLVDEYMSKKMKVDEFVTHTLPFEQINEAFELMH 362

Query: 369 EGKCLRCVL 377
            GK +R VL
Sbjct: 363 AGKSIRSVL 371


>ADHX_DROME (P46415) Alcohol dehydrogenase class III (EC 1.1.1.1)
           (Glutathione-dependent formaldehyde dehydrogenase) (EC
           1.2.1.1) (FDH) (FALDH) (Octanol dehydrogenase) (EC
           1.1.1.73)
          Length = 378

 Score =  517 bits (1332), Expect = e-146
 Identities = 251/377 (66%), Positives = 302/377 (79%), Gaps = 3/377 (0%)

Query: 3   SSTEGQVITCKAAVAWEPNKPLTIEDVEVAPPQANEVRIQILFTALCHTDAYTWSGKDPE 62
           S+TEG+VITCKAAVAWE  KPL IED+EVAPP+A+EVRI+I  T +CHTDA+T SG DPE
Sbjct: 1   SATEGKVITCKAAVAWEAKKPLVIEDIEVAPPKAHEVRIKITATGVCHTDAFTLSGADPE 60

Query: 63  GLFPCILGHEAAGIVESVGEGVTDVKPGDHVIPCYQAECGECKFCKSGKTNLCGKVRAAT 122
           GLFP +LGHE AGIVESVGEGVT+ K GDHVI  Y  +C ECKFCKSGKTNLC K+R   
Sbjct: 61  GLFPVVLGHEGAGIVESVGEGVTNFKAGDHVIALYIPQCNECKFCKSGKTNLCQKIRLTQ 120

Query: 123 GVGVMMNDRKPRFSIKGKPIYHFMGTSTFSQYTVVHDVSVAKIHPDAALDKVCLLGCGVP 182
           G GV M +   R S KG+ ++HFMGTSTF++YTVV D+S+ KI+  A L+KVCLLGCG+ 
Sbjct: 121 GAGV-MPEGTSRLSCKGQQLFHFMGTSTFAEYTVVADISLTKINEKAPLEKVCLLGCGIS 179

Query: 183 TGLGAVWNTAKVEPGSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDSNKFDTAKNFGV 242
           TG GA  NTAKVE GS  A++GLG VGLAV  G K AGA +I GIDI+ +KF+ AK FG 
Sbjct: 180 TGYGAALNTAKVEAGSTCAVWGLGAVGLAVGLGCKKAGAGKIYGIDINPDKFELAKKFGF 239

Query: 243 TEFINPKD--HEKPIQQVISDLTDGGVDYSFECIGNVSVMRSALECTHKGWGTSVVVGVA 300
           T+F+NPKD   +  IQ  + DLTDGG DY+FECIGNV+ MRSALE THKGWGTSVV+GVA
Sbjct: 240 TDFVNPKDVADKGSIQNYLIDLTDGGFDYTFECIGNVNTMRSALEATHKGWGTSVVIGVA 299

Query: 301 ASGQEISTRPFQLVTGRVWKGTAFGGFKSRSQVPWLVEKYLKKEIKVDEYVTHNLTLAEI 360
            +GQEISTRPFQLV GRVWKG+AFGG++S S VP LVE YLKK++ VDE++TH L L++I
Sbjct: 300 GAGQEISTRPFQLVVGRVWKGSAFGGWRSVSDVPKLVEDYLKKDLLVDEFITHELPLSQI 359

Query: 361 NEAFDLMHEGKCLRCVL 377
           NEAFDLMH+G+ +R ++
Sbjct: 360 NEAFDLMHKGESIRSII 376


>ADHL_GADMO (P81601) Alcohol dehydrogenase class III L chain (EC
           1.1.1.1) (Glutathione-dependent formaldehyde
           dehydrogenase) (EC 1.2.1.1) (FDH)
          Length = 375

 Score =  516 bits (1330), Expect = e-146
 Identities = 244/374 (65%), Positives = 299/374 (79%), Gaps = 1/374 (0%)

Query: 4   STEGQVITCKAAVAWEPNKPLTIEDVEVAPPQANEVRIQILFTALCHTDAYTWSGKDPEG 63
           +T G+ I C+AAVAWE  KPL++E+VEVAPPQA EVRI+I+ T +CHTDAYT SG DPEG
Sbjct: 1   ATVGKTIRCRAAVAWEAGKPLSMEEVEVAPPQAGEVRIKIVATGICHTDAYTLSGSDPEG 60

Query: 64  LFPCILGHEAAGIVESVGEGVTDVKPGDHVIPCYQAECGECKFCKSGKTNLCGKVRAATG 123
           +FP +LGHE AGIVESVGEGVT  K GD VIP Y  +CGECKFCK+ KTNLC K+R   G
Sbjct: 61  VFPSVLGHEGAGIVESVGEGVTKFKSGDAVIPLYVPQCGECKFCKNPKTNLCQKIRLTQG 120

Query: 124 VGVMMNDRKPRFSIKGKPIYHFMGTSTFSQYTVVHDVSVAKIHPDAALDKVCLLGCGVPT 183
            G+M N    RFS  G+ ++HFMG+STFS+YTVV ++S+AK+H  A LDKVCLLGC + T
Sbjct: 121 KGLMPNGTS-RFSCNGQVLFHFMGSSTFSEYTVVAEISLAKVHEKAPLDKVCLLGCAIST 179

Query: 184 GLGAVWNTAKVEPGSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDSNKFDTAKNFGVT 243
           G GA  NTAKVE GS  A+FGLG +GLAV  G ++AGASRII ID++ +KF  AK FG T
Sbjct: 180 GYGAALNTAKVEAGSTCAVFGLGALGLAVIMGCQAAGASRIIAIDVNPDKFRIAKEFGAT 239

Query: 244 EFINPKDHEKPIQQVISDLTDGGVDYSFECIGNVSVMRSALECTHKGWGTSVVVGVAASG 303
           + +NPKDH KP++QV+ ++TDGGVDYSFEC+GN++VMR+ALE  HKGWGTSV++GVAA+G
Sbjct: 240 DLVNPKDHSKPVEQVLVEMTDGGVDYSFECVGNIAVMRAALEACHKGWGTSVIIGVAAAG 299

Query: 304 QEISTRPFQLVTGRVWKGTAFGGFKSRSQVPWLVEKYLKKEIKVDEYVTHNLTLAEINEA 363
           QEISTRPFQLVTGR WKGTAFGG+KS   VP LVE+Y+ K++KVDE+VTH L   +I+E 
Sbjct: 300 QEISTRPFQLVTGRTWKGTAFGGYKSVESVPKLVEEYMNKKVKVDEFVTHTLPFEKIHEG 359

Query: 364 FDLMHEGKCLRCVL 377
           FDLM  GK +R VL
Sbjct: 360 FDLMGAGKSIRTVL 373


>ADHX_RABIT (O19053) Alcohol dehydrogenase class III chain (EC
           1.1.1.1) (Glutathione-dependent formaldehyde
           dehydrogenase) (EC 1.2.1.1) (FDH) (FALDH)
          Length = 373

 Score =  515 bits (1327), Expect = e-146
 Identities = 253/372 (68%), Positives = 296/372 (79%), Gaps = 1/372 (0%)

Query: 8   QVITCKAAVAWEPNKPLTIEDVEVAPPQANEVRIQILFTALCHTDAYTWSGKDPEGLFPC 67
           +VI CKAAVAWE  KPL+IE++EVAPP+A+EVRI+I  TA+CHTDAYT SG DPEG FP 
Sbjct: 3   KVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIFATAVCHTDAYTLSGADPEGCFPV 62

Query: 68  ILGHEAAGIVESVGEGVTDVKPGDHVIPCYQAECGECKFCKSGKTNLCGKVRAATGVGVM 127
           ILGHE AGIVESVGEGVT++K GD VIP Y  +CGECKFC + KTNLC K+R   G G +
Sbjct: 63  ILGHEGAGIVESVGEGVTNLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKG-L 121

Query: 128 MNDRKPRFSIKGKPIYHFMGTSTFSQYTVVHDVSVAKIHPDAALDKVCLLGCGVPTGLGA 187
           M D   RF+ KGK I H+MGTSTFS+YTVV D+SVAKI P A LDKVCLLGCG+ TG GA
Sbjct: 122 MPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPSAPLDKVCLLGCGISTGYGA 181

Query: 188 VWNTAKVEPGSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDSNKFDTAKNFGVTEFIN 247
             NTAKVEPGS  A+FGLG VGLA   G K+AGASRII +DI+ +KF  AK FG TE IN
Sbjct: 182 ALNTAKVEPGSTCAVFGLGGVGLAAIMGCKAAGASRIIAVDINKDKFARAKEFGATECIN 241

Query: 248 PKDHEKPIQQVISDLTDGGVDYSFECIGNVSVMRSALECTHKGWGTSVVVGVAASGQEIS 307
           P+D  KPIQ+V+ + TDGGVDYSFECIGNV VMR+ALE  HKGWG SVVVGVA +G+EIS
Sbjct: 242 PQDFSKPIQEVLVEKTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAGAGEEIS 301

Query: 308 TRPFQLVTGRVWKGTAFGGFKSRSQVPWLVEKYLKKEIKVDEYVTHNLTLAEINEAFDLM 367
           TRPFQLVTGR WKGTAFGG+KS   VP LV +Y+ K+I VDE+VT+ L+  +INEAF+LM
Sbjct: 302 TRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKINVDEFVTNTLSFDQINEAFELM 361

Query: 368 HEGKCLRCVLAL 379
           H GK +R V+ +
Sbjct: 362 HSGKSIRTVVKI 373


>ADHX_OCTVU (P81431) Alcohol dehydrogenase class III (EC 1.1.1.1)
           (Glutathione-dependent formaldehyde dehydrogenase) (EC
           1.2.1.1) (FDH)
          Length = 378

 Score =  508 bits (1309), Expect = e-144
 Identities = 243/371 (65%), Positives = 299/371 (80%), Gaps = 1/371 (0%)

Query: 7   GQVITCKAAVAWEPNKPLTIEDVEVAPPQANEVRIQILFTALCHTDAYTWSGKDPEGLFP 66
           G+ I C AA+AWE  KPL+IE+VEVAPP++ EVRI+IL + +CHTDAYT  G DPEG+FP
Sbjct: 5   GKPIKCMAAIAWEAKKPLSIEEVEVAPPKSGEVRIKILHSGVCHTDAYTLEGIDPEGIFP 64

Query: 67  CILGHEAAGIVESVGEGVTDVKPGDHVIPCYQAECGECKFCKSGKTNLCGKVRAATGVGV 126
            ILGHE AGIVES+GEGVT VKPGD VIP Y  +C ECKFC + KTNLC K+R   G GV
Sbjct: 65  VILGHEGAGIVESIGEGVTSVKPGDTVIPLYVPQCYECKFCLNPKTNLCQKIRVTQGKGV 124

Query: 127 MMNDRKPRFSIKGKPIYHFMGTSTFSQYTVVHDVSVAKIHPDAALDKVCLLGCGVPTGLG 186
           M  D   RF+ KGK ++HFMG STFS++TVV ++S+AK++P AALDKVCLLGCG+ TG G
Sbjct: 125 MP-DGTTRFTCKGKEVFHFMGCSTFSEFTVVAEISIAKVNPKAALDKVCLLGCGISTGYG 183

Query: 187 AVWNTAKVEPGSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDSNKFDTAKNFGVTEFI 246
           A  NTA VE GS  A++GLG VGLAVA G K+AGA+RIIGIDI+ +KF+  K FG+TEF+
Sbjct: 184 AALNTAAVEKGSNCAVWGLGAVGLAVAMGCKAAGAARIIGIDINESKFEIGKKFGITEFV 243

Query: 247 NPKDHEKPIQQVISDLTDGGVDYSFECIGNVSVMRSALECTHKGWGTSVVVGVAASGQEI 306
           NPK   K +Q+V+ ++TD GVD++FECIGNV VMR+ALE  HKGWGTSV+VGVAA G+EI
Sbjct: 244 NPKKFCKSVQKVLGEMTDVGVDFTFECIGNVGVMRAALESCHKGWGTSVIVGVAAHGEEI 303

Query: 307 STRPFQLVTGRVWKGTAFGGFKSRSQVPWLVEKYLKKEIKVDEYVTHNLTLAEINEAFDL 366
           STRPFQLVTGRVWKGTAFGGFKSR  VP LV+ Y+ K++ +DE+V+H L+  +INEAFDL
Sbjct: 304 STRPFQLVTGRVWKGTAFGGFKSRDSVPKLVDDYMNKKLLLDEFVSHKLSFKKINEAFDL 363

Query: 367 MHEGKCLRCVL 377
           MH+G+ +R VL
Sbjct: 364 MHKGESIRAVL 374


>ADHX_MYXGL (P80360) Alcohol dehydrogenase class III (EC 1.1.1.1)
           (Glutathione-dependent formaldehyde dehydrogenase) (EC
           1.2.1.1) (FDH) (FALDH)
          Length = 376

 Score =  492 bits (1267), Expect = e-139
 Identities = 238/377 (63%), Positives = 289/377 (76%), Gaps = 1/377 (0%)

Query: 3   SSTEGQVITCKAAVAWEPNKPLTIEDVEVAPPQANEVRIQILFTALCHTDAYTWSGKDPE 62
           S  +GQVI CKAAVAWE  KPL++E++EVAPP+A+EVR+++L TA+CHTDAYT SG DPE
Sbjct: 1   SKMDGQVIHCKAAVAWEAKKPLSLEEIEVAPPKAHEVRMKVLATAVCHTDAYTLSGVDPE 60

Query: 63  GLFPCILGHEAAGIVESVGEGVTDVKPGDHVIPCYQAECGECKFCKSGKTNLCGKVRAAT 122
           G FP +LGHE AGIVESVGEGVT  KPGD VIP Y  +CGECKFC + KTNLC K+R   
Sbjct: 61  GSFPVVLGHEGAGIVESVGEGVTKFKPGDSVIPLYIPQCGECKFCLNPKTNLCQKIRVTQ 120

Query: 123 GVGVMMNDRKPRFSIKGKPIYHFMGTSTFSQYTVVHDVSVAKIHPDAALDKVCLLGCGVP 182
           G G MM D   R + +GK +YHFMG STFS+Y VV D+S+ ++ P+A  D+VCLLGCGV 
Sbjct: 121 GKG-MMPDGTSRLTCRGKSLYHFMGASTFSEYAVVADISLCRVAPEAPPDRVCLLGCGVS 179

Query: 183 TGLGAVWNTAKVEPGSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDSNKFDTAKNFGV 242
           TG GA  NTAKVEPGS  AIFGLG VGLA   G + AGASRII ID + +KF+ A+ FG 
Sbjct: 180 TGYGAPLNTAKVEPGSTCAIFGLGAVGLAAIMGCRVAGASRIIAIDRNPDKFEKARIFGA 239

Query: 243 TEFINPKDHEKPIQQVISDLTDGGVDYSFECIGNVSVMRSALECTHKGWGTSVVVGVAAS 302
           T+ + P   +KPI QV+ ++TDGG+DY+FEC+GNV +MR+ALE  HKGWG SV++GVA  
Sbjct: 240 TDCVVPDASDKPISQVLGEMTDGGLDYTFECVGNVGIMRAALESCHKGWGVSVILGVAGG 299

Query: 303 GQEISTRPFQLVTGRVWKGTAFGGFKSRSQVPWLVEKYLKKEIKVDEYVTHNLTLAEINE 362
           GQEISTRPFQLVTGR WKG AFGG+KS   VP LV+ Y+  +I VDE+V+H+L    INE
Sbjct: 300 GQEISTRPFQLVTGRTWKGAAFGGWKSVESVPKLVDDYMAGKIMVDEFVSHSLPFDSINE 359

Query: 363 AFDLMHEGKCLRCVLAL 379
           AFDLMH GK +R VL L
Sbjct: 360 AFDLMHAGKSIRTVLQL 376


>ADH3_ECOLI (P25437) Alcohol dehydrogenase class III (EC 1.1.1.1)
           (Glutathione-dependent formaldehyde dehydrogenase) (EC
           1.2.1.1) (FDH) (FALDH)
          Length = 369

 Score =  485 bits (1248), Expect = e-137
 Identities = 228/365 (62%), Positives = 289/365 (78%), Gaps = 1/365 (0%)

Query: 13  KAAVAWEPNKPLTIEDVEVAPPQANEVRIQILFTALCHTDAYTWSGKDPEGLFPCILGHE 72
           +AAVA+ P KPL I +++VAPP+  EV I++  T +CHTDA+T SG DPEG+FP +LGHE
Sbjct: 4   RAAVAFAPGKPLEIVEIDVAPPKKGEVLIKVTHTGVCHTDAFTLSGDDPEGVFPVVLGHE 63

Query: 73  AAGIVESVGEGVTDVKPGDHVIPCYQAECGECKFCKSGKTNLCGKVRAATGVGVMMNDRK 132
            AG+V  VGEGVT VKPGDHVIP Y AECGEC+FC+SGKTNLC  VR   G G +M D  
Sbjct: 64  GAGVVVEVGEGVTSVKPGDHVIPLYTAECGECEFCRSGKTNLCVAVRETQGKG-LMPDGT 122

Query: 133 PRFSIKGKPIYHFMGTSTFSQYTVVHDVSVAKIHPDAALDKVCLLGCGVPTGLGAVWNTA 192
            RFS  G+P+YH+MG STFS+YTVV +VS+AKI+P+A  + VCLLGCGV TG+GAV NTA
Sbjct: 123 TRFSYNGQPLYHYMGCSTFSEYTVVAEVSLAKINPEANHEHVCLLGCGVTTGIGAVHNTA 182

Query: 193 KVEPGSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDSNKFDTAKNFGVTEFINPKDHE 252
           KV+PG  VA+FGLG +GLAV +GA+ A A RII ID +  KFD A+ FG T+ INP D++
Sbjct: 183 KVQPGDSVAVFGLGAIGLAVVQGARQAKAGRIIAIDTNPKKFDLARRFGATDCINPNDYD 242

Query: 253 KPIQQVISDLTDGGVDYSFECIGNVSVMRSALECTHKGWGTSVVVGVAASGQEISTRPFQ 312
           KPI+ V+ D+   G+D++FECIGNV+VMR+ALE  H+GWG SV++GVA +GQEISTRPFQ
Sbjct: 243 KPIKDVLLDINKWGIDHTFECIGNVNVMRAALESAHRGWGQSVIIGVAVAGQEISTRPFQ 302

Query: 313 LVTGRVWKGTAFGGFKSRSQVPWLVEKYLKKEIKVDEYVTHNLTLAEINEAFDLMHEGKC 372
           LVTGRVWKG+AFGG K RSQ+P +VE  +K +I ++ +VTH ++L EIN+AFDLMHEGK 
Sbjct: 303 LVTGRVWKGSAFGGVKGRSQLPGMVEDAMKGDIDLEPFVTHTMSLDEINDAFDLMHEGKS 362

Query: 373 LRCVL 377
           +R V+
Sbjct: 363 IRTVI 367


>ADH_FRAAN (P17648) Alcohol dehydrogenase (EC 1.1.1.1)
          Length = 380

 Score =  482 bits (1241), Expect = e-136
 Identities = 224/377 (59%), Positives = 285/377 (75%)

Query: 3   SSTEGQVITCKAAVAWEPNKPLTIEDVEVAPPQANEVRIQILFTALCHTDAYTWSGKDPE 62
           SSTEG+VI C+AAVAWE  KPL IE+VEVAPPQAN VR++IL+T+LCHTD Y W  K   
Sbjct: 2   SSTEGKVICCRAAVAWEAGKPLVIEEVEVAPPQANVVRVKILYTSLCHTDVYFWEAKGQN 61

Query: 63  GLFPCILGHEAAGIVESVGEGVTDVKPGDHVIPCYQAECGECKFCKSGKTNLCGKVRAAT 122
            LFP I GHEA GIVESVGEGVTD+K GDHV+P +  EC EC  CKS ++N+C  +R  T
Sbjct: 62  PLFPRIYGHEAGGIVESVGEGVTDLKAGDHVLPVFTGECKECDHCKSEESNMCDLLRINT 121

Query: 123 GVGVMMNDRKPRFSIKGKPIYHFMGTSTFSQYTVVHDVSVAKIHPDAALDKVCLLGCGVP 182
             GVM+ND K RFSIKGKPIYHF+GTSTFS YTV H   +AKI+P + LDKVC+L CG+ 
Sbjct: 122 DRGVMLNDGKSRFSIKGKPIYHFVGTSTFSVYTVTHVGCLAKINPQSPLDKVCILSCGIS 181

Query: 183 TGLGAVWNTAKVEPGSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDSNKFDTAKNFGV 242
           TGLGA  N  K + GS VA+FGLG VGLA AEGA+ AGASRIIG+D++SN+F+ AK FG+
Sbjct: 182 TGLGATLNVRKPKKGSTVAVFGLGAVGLAAAEGARMAGASRIIGVDLNSNRFEEAKKFGI 241

Query: 243 TEFINPKDHEKPIQQVISDLTDGGVDYSFECIGNVSVMRSALECTHKGWGTSVVVGVAAS 302
           TEF+NPKDH+KP+Q+VI++LT+GGVD S EC GN+  M  A EC H GWG +V+VGV   
Sbjct: 242 TEFVNPKDHKKPVQEVIAELTNGGVDRSIECTGNIQAMIPAFECVHDGWGVAVLVGVPHK 301

Query: 303 GQEISTRPFQLVTGRVWKGTAFGGFKSRSQVPWLVEKYLKKEIKVDEYVTHNLTLAEINE 362
               +T P   +  R  KGT FG +K R+ +P +VEKY+ KE++VD+++TH L  ++IN+
Sbjct: 302 DAVFTTHPMNFLNERTLKGTFFGNYKPRTDIPSVVEKYMNKELEVDKFITHQLPFSQINK 361

Query: 363 AFDLMHEGKCLRCVLAL 379
           AFD M +G+ +RC++ +
Sbjct: 362 AFDYMLKGEGIRCIITM 378


>ADHX_CAEEL (Q17335) Alcohol dehydrogenase class III (EC 1.1.1.1)
           (Glutathione-dependent formaldehyde dehydrogenase) (EC
           1.2.1.1) (FDH) (FALDH)
          Length = 384

 Score =  482 bits (1241), Expect = e-136
 Identities = 231/380 (60%), Positives = 290/380 (75%), Gaps = 5/380 (1%)

Query: 3   SSTEGQVITCKAAVAWEPNKPLTIEDVEVAPPQANEVRIQILFTALCHTDAYTWSGKDPE 62
           SST GQVI CKAAVAW    PL+IE ++VAPP+A+EVR++IL+TA+CHTDAYT  G DPE
Sbjct: 2   SSTAGQVINCKAAVAWSAKAPLSIETIQVAPPKAHEVRVKILYTAVCHTDAYTLDGHDPE 61

Query: 63  GLFPCILGHEAAGIVESVGEGVTDVKPGDHVIPCYQAECGECKFCKSGKTNLCGKVRAAT 122
           GLFP +LGHE +GIVESVGEGVT   PGDHV+P Y  +C EC++CK+ KTNLC K+R + 
Sbjct: 62  GLFPVVLGHEGSGIVESVGEGVTGFAPGDHVVPLYVPQCKECEYCKNPKTNLCQKIRISQ 121

Query: 123 GVGVMMNDRKPRFSIKGKPIYHFMGTSTFSQYTVVHDVSVAKIHPDAALDKVCLLGCGVP 182
           G G  M D   RF+  GK ++HFMG STFS+YTVV D+S+ K++P+A L+KV LLGCG+ 
Sbjct: 122 GNG-FMPDGSSRFTCNGKQLFHFMGCSTFSEYTVVADISLCKVNPEAPLEKVSLLGCGIS 180

Query: 183 TGLGAVWNTAKVEPGSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDSNKFDTAKNFGV 242
           TG GAV NT KVE GS VA++GLG VGLAV  GAK+AGA +I+GID+  +KF++AK FG 
Sbjct: 181 TGYGAVLNTCKVEEGSTVAVWGLGAVGLAVIMGAKAAGAKKIVGIDLIESKFESAKFFGA 240

Query: 243 TEFINPKDHEKP----IQQVISDLTDGGVDYSFECIGNVSVMRSALECTHKGWGTSVVVG 298
           TE INPK  E P     Q  + +  DGG DY+FECIGNV  MR ALE  HKGWG S ++G
Sbjct: 241 TECINPKSVELPEGKSFQAWLVEQFDGGFDYTFECIGNVHTMRQALEAAHKGWGVSCIIG 300

Query: 299 VAASGQEISTRPFQLVTGRVWKGTAFGGFKSRSQVPWLVEKYLKKEIKVDEYVTHNLTLA 358
           VA +GQEI+TRPFQLVTGR WKGTAFGG+KS   VP LV+ Y+ K++ +DE++TH   + 
Sbjct: 301 VAGAGQEIATRPFQLVTGRTWKGTAFGGWKSVESVPRLVDDYMNKKLLIDEFITHRWNID 360

Query: 359 EINEAFDLMHEGKCLRCVLA 378
           +IN AFD++H+G+ LR VLA
Sbjct: 361 DINTAFDVLHKGESLRSVLA 380


>ADH3_SYNY3 (P73138) Probable alcohol dehydrogenase class III (EC
           1.1.1.1) (Glutathione-dependent formaldehyde
           dehydrogenase) (EC 1.2.1.1) (FDH) (FALDH)
          Length = 369

 Score =  482 bits (1240), Expect = e-136
 Identities = 233/365 (63%), Positives = 287/365 (77%), Gaps = 1/365 (0%)

Query: 13  KAAVAWEPNKPLTIEDVEVAPPQANEVRIQILFTALCHTDAYTWSGKDPEGLFPCILGHE 72
           +AAVA+E  KPL I +++VAPPQ  EV ++I  T +CHTDA+T SG DPEGLFP +LGHE
Sbjct: 4   RAAVAFEVGKPLQIVEIDVAPPQQGEVLVKITHTGVCHTDAFTLSGDDPEGLFPVVLGHE 63

Query: 73  AAGIVESVGEGVTDVKPGDHVIPCYQAECGECKFCKSGKTNLCGKVRAATGVGVMMNDRK 132
            AGIV  VGEGVT V+ GDHVIP Y AECG+C FC+SGKTNLC  VRA  G GVM  D  
Sbjct: 64  GAGIVVEVGEGVTSVQLGDHVIPLYTAECGKCLFCRSGKTNLCVAVRATQGKGVMP-DGT 122

Query: 133 PRFSIKGKPIYHFMGTSTFSQYTVVHDVSVAKIHPDAALDKVCLLGCGVPTGLGAVWNTA 192
            RFS  G+ +YH+MG STFS+YTVV +VS+AKI+P+A  + VCLLGCGV TG+GAV NTA
Sbjct: 123 SRFSYNGQSLYHYMGCSTFSEYTVVAEVSLAKINPEANHEHVCLLGCGVTTGIGAVHNTA 182

Query: 193 KVEPGSIVAIFGLGTVGLAVAEGAKSAGASRIIGIDIDSNKFDTAKNFGVTEFINPKDHE 252
           KV+PG  VA+FGLG +GLAV +GA+ A A RII ID +  KF+ AK  G T+ INPKDH+
Sbjct: 183 KVQPGDSVAVFGLGGIGLAVVQGARQAKAGRIIAIDTNPAKFELAKQMGATDCINPKDHD 242

Query: 253 KPIQQVISDLTDGGVDYSFECIGNVSVMRSALECTHKGWGTSVVVGVAASGQEISTRPFQ 312
           +PIQQVI ++T  GVD+SFECIGNV VMRSALEC H+GWG SV++GVA +GQEISTRPFQ
Sbjct: 243 QPIQQVIVEMTGWGVDHSFECIGNVEVMRSALECAHRGWGQSVIIGVAGAGQEISTRPFQ 302

Query: 313 LVTGRVWKGTAFGGFKSRSQVPWLVEKYLKKEIKVDEYVTHNLTLAEINEAFDLMHEGKC 372
           LVTGR W GTAFGG K RSQ+P +VE+ ++ EI++  +VTH + L +IN+AFDLMH+GK 
Sbjct: 303 LVTGRKWMGTAFGGVKGRSQLPGMVEQSMRGEIQLAPFVTHTMELKDINQAFDLMHDGKS 362

Query: 373 LRCVL 377
           +R V+
Sbjct: 363 IRSVI 367


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.319    0.136    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,777,291
Number of Sequences: 164201
Number of extensions: 1967932
Number of successful extensions: 6034
Number of sequences better than 10.0: 274
Number of HSP's better than 10.0 without gapping: 221
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 5457
Number of HSP's gapped (non-prelim): 313
length of query: 380
length of database: 59,974,054
effective HSP length: 112
effective length of query: 268
effective length of database: 41,583,542
effective search space: 11144389256
effective search space used: 11144389256
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)