BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC146807.6 + phase: 0
(374 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ANK1_HUMAN (P16157) Ankyrin 1 (Erythrocyte ankyrin) (Ankyrin R) 56 2e-07
ANK1_MOUSE (Q02357) Ankyrin 1 (Erythrocyte ankyrin) 53 1e-06
PA26_HUMAN (O60733) 85 kDa calcium-independent phospholipase A2 ... 52 2e-06
BAR1_RAT (Q9QZH2) BRCA1-associated RING domain protein 1 (BARD-1) 52 2e-06
HT16_HYDAT (P53356) Tyrosine-protein kinase HTK16 (EC 2.7.1.112) 52 2e-06
YMV8_YEAST (Q04749) Hypothetical 47.1 kDa protein in NCA1-HMS1 i... 51 4e-06
PA26_MOUSE (P97819) 85 kDa calcium-independent phospholipase A2 ... 51 4e-06
ANK2_HUMAN (Q01484) Ankyrin 2 (Brain ankyrin) (Ankyrin B) (Ankyr... 51 4e-06
RFXK_MOUSE (Q9Z205) DNA-binding protein RFXANK (Regulatory facto... 51 5e-06
LCTA_LATMA (Q9XZC0) Alpha-latrocrustotoxin (Alpha-LCT) (Crusta1) 50 7e-06
RIK4_HUMAN (P57078) Serine/threonine-protein kinase RIPK4 (EC 2.... 50 9e-06
PSDA_HUMAN (O75832) 26S proteasome non-ATPase regulatory subunit... 50 9e-06
PPGA_MOUSE (Q923M0) Protein phosphatase 1 regulatory inhibitor s... 50 9e-06
PPGA_HUMAN (Q96I34) Protein phosphatase 1 regulatory inhibitor s... 50 1e-05
PA26_RAT (P97570) 85 kDa calcium-independent phospholipase A2 (E... 50 1e-05
AN28_HUMAN (O15084) Ankyrin repeat domain protein 28 (Fragment) 50 1e-05
ANK3_HUMAN (Q12955) Ankyrin 3 (ANK-3) (Ankyrin G) 49 2e-05
PSDA_MOUSE (Q9Z2X2) 26S proteasome non-ATPase regulatory subunit... 49 2e-05
LATA_LATMA (P23631) Alpha-latrotoxin precursor (Alpha-LTX) 49 3e-05
ASB8_MOUSE (Q91ZT9) Ankyrin repeat and SOCS box protein 8 (ASB-8) 49 3e-05
>ANK1_HUMAN (P16157) Ankyrin 1 (Erythrocyte ankyrin) (Ankyrin R)
Length = 1880
Score = 55.8 bits (133), Expect = 2e-07
Identities = 39/103 (37%), Positives = 54/103 (51%), Gaps = 10/103 (9%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
VN A T LH AA G+ + V+LLL+ NAN + AT AG TPLH AA
Sbjct: 462 VNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATT----------AGHTPLHIAAR 511
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVARMWGRHWLEPLL 134
G+++ LL K A++ + G+ PL VA +G+ + LL
Sbjct: 512 EGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELL 554
Score = 51.2 bits (121), Expect = 4e-06
Identities = 30/84 (35%), Positives = 44/84 (51%), Gaps = 10/84 (11%)
Query: 39 GITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCC 98
G++ +HMAA + DCV+LLL +A T + TPLH AA G+ +
Sbjct: 304 GLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDH----------LTPLHVAAHCGHHRVA 353
Query: 99 QILLSKGATRMALNCNGWLPLDVA 122
++LL KGA + NG+ PL +A
Sbjct: 354 KVLLDKGAKPNSRALNGFTPLHIA 377
Score = 47.8 bits (112), Expect = 5e-05
Identities = 34/91 (37%), Positives = 43/91 (46%), Gaps = 10/91 (10%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
VN T GIT LH+A+ G V+LLLD A T TPLH AA
Sbjct: 231 VNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDE----------LTPLHCAAR 280
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVA 122
G+++ +ILL GA A NG P+ +A
Sbjct: 281 NGHVRISEILLDHGAPIQAKTKNGLSPIHMA 311
Score = 47.0 bits (110), Expect = 8e-05
Identities = 32/90 (35%), Positives = 43/90 (47%), Gaps = 10/90 (11%)
Query: 33 NKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACG 92
N AG T LH+AA G+ + V LL+ A+ + T G TPLH AA
Sbjct: 496 NLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKK----------GFTPLHVAAKY 545
Query: 93 GNLKCCQILLSKGATRMALNCNGWLPLDVA 122
G ++ ++LL + A A NG PL VA
Sbjct: 546 GKVRVAELLLERDAHPNAAGKNGLTPLHVA 575
Score = 46.6 bits (109), Expect = 1e-04
Identities = 30/94 (31%), Positives = 43/94 (44%), Gaps = 10/94 (10%)
Query: 33 NKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACG 92
N + G+T LH+AA G+ + V LLL AN + +G TPLH A
Sbjct: 628 NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGN----------KSGLTPLHLVAQE 677
Query: 93 GNLKCCQILLSKGATRMALNCNGWLPLDVARMWG 126
G++ +L+ G A G+ PL VA +G
Sbjct: 678 GHVPVADVLIKHGVMVDATTRMGYTPLHVASHYG 711
Score = 45.8 bits (107), Expect = 2e-04
Identities = 32/92 (34%), Positives = 46/92 (49%), Gaps = 10/92 (10%)
Query: 35 TADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGN 94
T G TALH+AAL G + V+ L++ AN +A + G TPL+ AA +
Sbjct: 73 TTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQ----------KGFTPLYMAAQENH 122
Query: 95 LKCCQILLSKGATRMALNCNGWLPLDVARMWG 126
L+ + LL GA + +G+ PL VA G
Sbjct: 123 LEVVKFLLENGANQNVATEDGFTPLAVALQQG 154
Score = 45.4 bits (106), Expect = 2e-04
Identities = 34/101 (33%), Positives = 48/101 (46%), Gaps = 11/101 (10%)
Query: 34 KTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGG 93
KT D +T LH AA NG+ ++LLD A A T + G +P+H AA G
Sbjct: 267 KTKDE-LTPLHCAARNGHVRISEILLDHGAPIQAKTKN----------GLSPIHMAAQGD 315
Query: 94 NLKCCQILLSKGATRMALNCNGWLPLDVARMWGRHWLEPLL 134
+L C ++LL A + + PL VA G H + +L
Sbjct: 316 HLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVL 356
Score = 44.3 bits (103), Expect = 5e-04
Identities = 29/84 (34%), Positives = 43/84 (50%), Gaps = 10/84 (11%)
Query: 39 GITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCC 98
G T LH+AA G +LLL+ +A+ +AA + G TPLH A NL
Sbjct: 535 GFTPLHVAAKYGKVRVAELLLERDAHPNAAGKN----------GLTPLHVAVHHNNLDIV 584
Query: 99 QILLSKGATRMALNCNGWLPLDVA 122
++LL +G + + NG+ PL +A
Sbjct: 585 KLLLPRGGSPHSPAWNGYTPLHIA 608
Score = 43.1 bits (100), Expect = 0.001
Identities = 30/95 (31%), Positives = 45/95 (46%), Gaps = 10/95 (10%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
V+ T G T LH+A+ G V+ LL A+ +A T G +PLH AA
Sbjct: 693 VDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTK----------LGYSPLHQAAQ 742
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVARMWG 126
G+ +LL GA+ ++ +G PL +A+ G
Sbjct: 743 QGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLG 777
Score = 40.0 bits (92), Expect = 0.010
Identities = 30/94 (31%), Positives = 42/94 (43%), Gaps = 10/94 (10%)
Query: 33 NKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACG 92
N A G T LH+A + ++LLL A+ A T +G TPLH A+
Sbjct: 364 NSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTE----------SGLTPLHVASFM 413
Query: 93 GNLKCCQILLSKGATRMALNCNGWLPLDVARMWG 126
G+L + LL +GA+ N PL +A G
Sbjct: 414 GHLPIVKNLLQRGASPNVSNVKVETPLHMAARAG 447
Score = 38.9 bits (89), Expect = 0.021
Identities = 29/102 (28%), Positives = 44/102 (42%), Gaps = 10/102 (9%)
Query: 33 NKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACG 92
N G+T LH+A + D V+LLL + + ++ G TPLH AA
Sbjct: 562 NAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWN----------GYTPLHIAAKQ 611
Query: 93 GNLKCCQILLSKGATRMALNCNGWLPLDVARMWGRHWLEPLL 134
++ + LL G + A + G PL +A G + LL
Sbjct: 612 NQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALL 653
Score = 38.5 bits (88), Expect = 0.028
Identities = 39/147 (26%), Positives = 55/147 (36%), Gaps = 52/147 (35%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAAT---------------------- 69
VN + G T L+MAA + + V+ LL+ AN + AT
Sbjct: 103 VNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHL 162
Query: 70 YHYGT-----------------------------SMDLIG-AGSTPLHYAACGGNLKCCQ 99
+YGT + D++ G TPLH AA NL Q
Sbjct: 163 INYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQ 222
Query: 100 ILLSKGATRMALNCNGWLPLDVARMWG 126
+LL++GA+ NG PL +A G
Sbjct: 223 LLLNRGASVNFTPQNGITPLHIASRRG 249
Score = 38.5 bits (88), Expect = 0.028
Identities = 34/128 (26%), Positives = 52/128 (40%), Gaps = 17/128 (13%)
Query: 39 GITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCC 98
G T LH+AA + + LL +A+A + G TPLH AA G+ +
Sbjct: 601 GYTPLHIAAKQNQVEVARSLLQYGGSANAESVQ----------GVTPLHLAAQEGHAEMV 650
Query: 99 QILLSKGATRMALNCNGWLPLDVARMWGRHWLEPLLAPSSDTIVSSFPTSNYLLLPLMSV 158
+LLSK A N +G PL + G P +D ++ + +
Sbjct: 651 ALLLSKQANGNLGNKSGLTPLHLVAQEGH-------VPVADVLIKHGVMVDATTRMGYTP 703
Query: 159 LNIAREYG 166
L++A YG
Sbjct: 704 LHVASHYG 711
Score = 34.3 bits (77), Expect = 0.53
Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 10/103 (9%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
++ ++G+T LH+A+ G+ V+ LL A+ + + TPLH AA
Sbjct: 396 IDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKV----------ETPLHMAAR 445
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVARMWGRHWLEPLL 134
G+ + + LL A A + PL A G + LL
Sbjct: 446 AGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLL 488
>ANK1_MOUSE (Q02357) Ankyrin 1 (Erythrocyte ankyrin)
Length = 1862
Score = 53.1 bits (126), Expect = 1e-06
Identities = 31/84 (36%), Positives = 44/84 (51%), Gaps = 10/84 (11%)
Query: 39 GITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCC 98
G++ +HMAA + DCV+LLL NA T + TPLH AA G+ +
Sbjct: 301 GLSPIHMAAQGDHLDCVRLLLQYNAEIDDITLDH----------LTPLHVAAHCGHHRVA 350
Query: 99 QILLSKGATRMALNCNGWLPLDVA 122
++LL KGA + NG+ PL +A
Sbjct: 351 KVLLDKGAKPNSRALNGFTPLHIA 374
Score = 49.7 bits (117), Expect = 1e-05
Identities = 37/102 (36%), Positives = 50/102 (48%), Gaps = 10/102 (9%)
Query: 33 NKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACG 92
N A T LH AA G+ V+LLL+ A+ + AT AG TPLH AA
Sbjct: 460 NAKAKDDQTPLHCAARIGHTGMVKLLLENGASPNLAT----------TAGHTPLHTAARE 509
Query: 93 GNLKCCQILLSKGATRMALNCNGWLPLDVARMWGRHWLEPLL 134
G++ LL K A++ + G+ PL VA +G+ L LL
Sbjct: 510 GHVDTALALLEKEASQACMTKKGFTPLHVAAKYGKVRLAELL 551
Score = 47.8 bits (112), Expect = 5e-05
Identities = 34/91 (37%), Positives = 43/91 (46%), Gaps = 10/91 (10%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
VN T GIT LH+A+ G V+LLLD A T TPLH AA
Sbjct: 228 VNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETRTKDE----------LTPLHCAAR 277
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVA 122
G+++ +ILL GA A NG P+ +A
Sbjct: 278 NGHVRISEILLDHGAPIQAKTKNGLSPIHMA 308
Score = 47.4 bits (111), Expect = 6e-05
Identities = 30/94 (31%), Positives = 44/94 (45%), Gaps = 10/94 (10%)
Query: 33 NKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACG 92
N + G+T LH+AA G+ + V LLL AN + +G TPLH +
Sbjct: 625 NAESVQGVTPLHLAAQEGHTEMVALLLSKQANGNLGNK----------SGLTPLHLVSQE 674
Query: 93 GNLKCCQILLSKGATRMALNCNGWLPLDVARMWG 126
G++ +L+ G T A G+ PL VA +G
Sbjct: 675 GHVLVADVLIKHGVTVDATTRMGYTPLHVASHYG 708
Score = 45.8 bits (107), Expect = 2e-04
Identities = 32/92 (34%), Positives = 46/92 (49%), Gaps = 10/92 (10%)
Query: 35 TADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGN 94
T G TALH+AAL G + V+ L++ AN +A + G TPL+ AA +
Sbjct: 70 TTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQ----------KGFTPLYMAAQENH 119
Query: 95 LKCCQILLSKGATRMALNCNGWLPLDVARMWG 126
L+ + LL GA + +G+ PL VA G
Sbjct: 120 LEVVKFLLENGANQNVATEDGFTPLAVALQQG 151
Score = 45.1 bits (105), Expect = 3e-04
Identities = 31/95 (32%), Positives = 45/95 (46%), Gaps = 10/95 (10%)
Query: 40 ITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCCQ 99
+T LH AA NG+ ++LLD A A T + G +P+H AA G +L C +
Sbjct: 269 LTPLHCAARNGHVRISEILLDHGAPIQAKTKN----------GLSPIHMAAQGDHLDCVR 318
Query: 100 ILLSKGATRMALNCNGWLPLDVARMWGRHWLEPLL 134
+LL A + + PL VA G H + +L
Sbjct: 319 LLLQYNAEIDDITLDHLTPLHVAAHCGHHRVAKVL 353
Score = 45.1 bits (105), Expect = 3e-04
Identities = 31/95 (32%), Positives = 45/95 (46%), Gaps = 10/95 (10%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
V+ T G T LH+A+ G V+ LL A+ +A T G +PLH AA
Sbjct: 690 VDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTK----------LGYSPLHQAAQ 739
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVARMWG 126
G+ +LL GA+ ++ NG PL +A+ G
Sbjct: 740 QGHTDIVTLLLKNGASPNEVSSNGTTPLAIAKRLG 774
Score = 45.1 bits (105), Expect = 3e-04
Identities = 32/90 (35%), Positives = 40/90 (43%), Gaps = 10/90 (11%)
Query: 33 NKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACG 92
N AG T LH AA G+ D LL+ A+ + T G TPLH AA
Sbjct: 493 NLATTAGHTPLHTAAREGHVDTALALLEKEASQACMTKK----------GFTPLHVAAKY 542
Query: 93 GNLKCCQILLSKGATRMALNCNGWLPLDVA 122
G ++ ++LL A A NG PL VA
Sbjct: 543 GKVRLAELLLEHDAHPNAAGKNGLTPLHVA 572
Score = 43.9 bits (102), Expect = 7e-04
Identities = 29/84 (34%), Positives = 43/84 (50%), Gaps = 10/84 (11%)
Query: 39 GITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCC 98
G T LH+AA G +LLL+ +A+ +AA + G TPLH A NL
Sbjct: 532 GFTPLHVAAKYGKVRLAELLLEHDAHPNAAGKN----------GLTPLHVAVHHNNLDIV 581
Query: 99 QILLSKGATRMALNCNGWLPLDVA 122
++LL +G + + NG+ PL +A
Sbjct: 582 KLLLPRGGSPHSPAWNGYTPLHIA 605
Score = 40.4 bits (93), Expect = 0.007
Identities = 30/94 (31%), Positives = 42/94 (43%), Gaps = 10/94 (10%)
Query: 33 NKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACG 92
N A G T LH+A + ++LLL A+ A T +G TPLH A+
Sbjct: 361 NSRALNGFTPLHIACKKNHIRVMELLLKTGASIDAVTE----------SGLTPLHVASFM 410
Query: 93 GNLKCCQILLSKGATRMALNCNGWLPLDVARMWG 126
G+L + LL +GA+ N PL +A G
Sbjct: 411 GHLPIVKNLLQRGASPNVSNVKVETPLHMAARAG 444
Score = 39.3 bits (90), Expect = 0.016
Identities = 29/102 (28%), Positives = 44/102 (42%), Gaps = 10/102 (9%)
Query: 33 NKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACG 92
N G+T LH+A + D V+LLL + + ++ G TPLH AA
Sbjct: 559 NAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWN----------GYTPLHIAAKQ 608
Query: 93 GNLKCCQILLSKGATRMALNCNGWLPLDVARMWGRHWLEPLL 134
++ + LL G + A + G PL +A G + LL
Sbjct: 609 NQIEVARSLLQYGGSANAESVQGVTPLHLAAQEGHTEMVALL 650
Score = 38.9 bits (89), Expect = 0.021
Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 10/103 (9%)
Query: 39 GITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCC 98
G T LH+AA + + LL +A+A + G TPLH AA G+ +
Sbjct: 598 GYTPLHIAAKQNQIEVARSLLQYGGSANAESVQ----------GVTPLHLAAQEGHTEMV 647
Query: 99 QILLSKGATRMALNCNGWLPLDVARMWGRHWLEPLLAPSSDTI 141
+LLSK A N +G PL + G + +L T+
Sbjct: 648 ALLLSKQANGNLGNKSGLTPLHLVSQEGHVLVADVLIKHGVTV 690
Score = 38.5 bits (88), Expect = 0.028
Identities = 39/147 (26%), Positives = 55/147 (36%), Gaps = 52/147 (35%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAAT---------------------- 69
VN + G T L+MAA + + V+ LL+ AN + AT
Sbjct: 100 VNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHL 159
Query: 70 YHYGT-----------------------------SMDLIG-AGSTPLHYAACGGNLKCCQ 99
+YGT + D++ G TPLH AA NL Q
Sbjct: 160 INYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQ 219
Query: 100 ILLSKGATRMALNCNGWLPLDVARMWG 126
+LL++GA+ NG PL +A G
Sbjct: 220 LLLNRGASVNFTPQNGITPLHIASRRG 246
Score = 35.8 bits (81), Expect = 0.18
Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 10/103 (9%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
++ ++G+T LH+A+ G+ V+ LL A+ + + TPLH AA
Sbjct: 393 IDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKV----------ETPLHMAAR 442
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVARMWGRHWLEPLL 134
G+ + + LL A A + PL A G + LL
Sbjct: 443 AGHTEVAKYLLQNKAKANAKAKDDQTPLHCAARIGHTGMVKLL 485
Score = 35.4 bits (80), Expect = 0.24
Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 10/86 (11%)
Query: 41 TALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCCQI 100
T LHMAA G+ + + LL A A+A TPLH AA G+ ++
Sbjct: 435 TPLHMAARAGHTEVAKYLLQNKAKANAKAKD----------DQTPLHCAARIGHTGMVKL 484
Query: 101 LLSKGATRMALNCNGWLPLDVARMWG 126
LL GA+ G PL A G
Sbjct: 485 LLENGASPNLATTAGHTPLHTAAREG 510
>PA26_HUMAN (O60733) 85 kDa calcium-independent phospholipase A2 (EC
3.1.1.4) (iPLA2) (CaI-PLA2) (Group VI phospholipase A2)
(GVI PLA2)
Length = 806
Score = 52.4 bits (124), Expect = 2e-06
Identities = 36/96 (37%), Positives = 46/96 (47%), Gaps = 10/96 (10%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
VN T+ AG TALH+A + FDC +LL ANA A H G+TPLH A
Sbjct: 310 VNSTSSAGNTALHVAVMRNRFDCAIVLLTHGANADARGEH----------GNTPLHLAMS 359
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVARMWGR 127
N++ + L+ GA N G P +A GR
Sbjct: 360 KDNVEMIKALIVFGAEVDTPNDFGETPTFLASKIGR 395
Score = 30.4 bits (67), Expect = 7.6
Identities = 59/254 (23%), Positives = 99/254 (38%), Gaps = 53/254 (20%)
Query: 2 LTIKYCFNNLCILYSCYSFTSCRCSELSKFVNKTADAGITALHMAALNGYFDCVQLLLDL 61
L I+ CF++ I+ SC C+E + G T LH+A G + +L++L
Sbjct: 129 LGIRECFHHSRII-SC-----ANCAE--------NEEGCTPLHLACRKGDGE---ILVEL 171
Query: 62 NANASAATYHYGTSMDLIG-AGSTPLHYAACGGNLKCCQILLSKGATRM-ALNCNGWLPL 119
+ T MD+ G T HYA G N + Q+L + +N G PL
Sbjct: 172 -------VQYCHTQMDVTDYKGETVFHYAVQGDNSQVLQLLGRNAVAGLNQVNNQGLTPL 224
Query: 120 DVARMWGRHWLEPLL----------APSSDTIVSSFPTSNYLLLPLMSVLNIAR------ 163
+A G+ + +L P+ I S+ S ++ ++ ++
Sbjct: 225 HLACQLGKQEMVRVLLLCNARCNIMGPNGYPIHSAMKFSQKGCAEMIISMDSSQIHSKDP 284
Query: 164 EYGLHSPTTSSNEIDFCAVCLERPCTV-----AAEGCMHELCVR----CALYLCSTANVS 214
YG SP + + + L+R C V A +H +R CA+ L T +
Sbjct: 285 RYGA-SPLHWAKNAEMARMLLKRGCNVNSTSSAGNTALHVAVMRNRFDCAIVLL-THGAN 342
Query: 215 SEMHGPPGSVPCPL 228
++ G G+ P L
Sbjct: 343 ADARGEHGNTPLHL 356
>BAR1_RAT (Q9QZH2) BRCA1-associated RING domain protein 1 (BARD-1)
Length = 768
Score = 52.4 bits (124), Expect = 2e-06
Identities = 32/83 (38%), Positives = 44/83 (52%), Gaps = 10/83 (12%)
Query: 38 AGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKC 97
AG T LH A +G+ V+LLL NA + YH +PLH AA G++
Sbjct: 450 AGWTPLHEACSHGHLKIVELLLQHNALVNTTGYH----------NDSPLHDAAKNGHIDI 499
Query: 98 CQILLSKGATRMALNCNGWLPLD 120
++LLS GA+R A+N G P+D
Sbjct: 500 VKVLLSHGASRNAVNIFGERPVD 522
>HT16_HYDAT (P53356) Tyrosine-protein kinase HTK16 (EC 2.7.1.112)
Length = 757
Score = 52.0 bits (123), Expect = 2e-06
Identities = 37/122 (30%), Positives = 61/122 (49%), Gaps = 25/122 (20%)
Query: 26 SELSKFVNKTADAGITALHMAALNGYFDCVQLLLDLNANASA------------ATYHYG 73
S + + VN + +G+TALH++ NG D V +LL+ A+ASA Y++
Sbjct: 139 SVIKENVNARSISGLTALHISCSNGDNDIVAMLLNAGADASAIDANGRTPVQVVCFYNHA 198
Query: 74 TSMDLI-------------GAGSTPLHYAACGGNLKCCQILLSKGATRMALNCNGWLPLD 120
+++ L+ G PLH AA G+L+C ++LLS A+ + +G P D
Sbjct: 199 STLHLLISKGSADFLKRSPNNGWVPLHEAAMRGSLECVKVLLSFNASMYPRSLDGDTPRD 258
Query: 121 VA 122
+A
Sbjct: 259 LA 260
>YMV8_YEAST (Q04749) Hypothetical 47.1 kDa protein in NCA1-HMS1
intergenic region
Length = 426
Score = 51.2 bits (121), Expect = 4e-06
Identities = 29/100 (29%), Positives = 50/100 (50%), Gaps = 13/100 (13%)
Query: 27 ELSKFVNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPL 86
+ +F+N + G +H+A +N Y+ C+ LL+ + A+ MD G TPL
Sbjct: 97 QFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGVGADLWV--------MDT--NGDTPL 146
Query: 87 HYAACGGNLKCCQILLSKGATRMALNC---NGWLPLDVAR 123
H G++ C ++LL++G + N W P+DVA+
Sbjct: 147 HVCLEYGSISCMKMLLNEGEVSLDDNVRDKGNWKPIDVAQ 186
Score = 35.8 bits (81), Expect = 0.18
Identities = 24/88 (27%), Positives = 37/88 (41%), Gaps = 9/88 (10%)
Query: 39 GITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCC 98
G T +H+A + G+ + LLL H G + G P+H A +C
Sbjct: 75 GNTCVHLALMKGHEQTLHLLLQ---QFPRFINHRGEN------GRAPIHIACMNDYYQCL 125
Query: 99 QILLSKGATRMALNCNGWLPLDVARMWG 126
+L+ GA ++ NG PL V +G
Sbjct: 126 SLLIGVGADLWVMDTNGDTPLHVCLEYG 153
>PA26_MOUSE (P97819) 85 kDa calcium-independent phospholipase A2 (EC
3.1.1.4) (iPLA2) (CaI-PLA2) (Group VI phospholipase A2)
(GVI PLA2)
Length = 752
Score = 51.2 bits (121), Expect = 4e-06
Identities = 33/91 (36%), Positives = 45/91 (49%), Gaps = 10/91 (10%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
V+ T+ +G TALH+A + FDCV +LL ANA A H G+TPLH A
Sbjct: 310 VDSTSSSGNTALHVAVMRNRFDCVMVLLTYGANAGARGEH----------GNTPLHLAMS 359
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVA 122
N++ + L+ GA N G P +A
Sbjct: 360 KDNMEMVKALIVFGAEVDTPNDFGETPALIA 390
Score = 32.7 bits (73), Expect = 1.5
Identities = 19/78 (24%), Positives = 38/78 (48%), Gaps = 11/78 (14%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
+N+ + G+T LH+A G + V++LL NA +++G G P+H A
Sbjct: 213 LNQVNNQGLTPLHLACKMGKQEMVRVLLLCNARC-----------NIMGPGGFPIHTAMK 261
Query: 92 GGNLKCCQILLSKGATRM 109
C ++++S + ++
Sbjct: 262 FSQKGCAEMIISMDSNQI 279
>ANK2_HUMAN (Q01484) Ankyrin 2 (Brain ankyrin) (Ankyrin B) (Ankyrin,
nonerythroid)
Length = 3924
Score = 51.2 bits (121), Expect = 4e-06
Identities = 35/91 (38%), Positives = 47/91 (51%), Gaps = 10/91 (10%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
V+ TA GIT LH+A+ G + V+LLLD A T G TPLH AA
Sbjct: 259 VDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRD----------GLTPLHCAAR 308
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVA 122
G+ + ++LL +GA +A NG PL +A
Sbjct: 309 SGHDQVVELLLERGAPLLARTKNGLSPLHMA 339
Score = 50.1 bits (118), Expect = 9e-06
Identities = 34/84 (40%), Positives = 42/84 (49%), Gaps = 10/84 (11%)
Query: 39 GITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCC 98
G T LH+AA G D +LLL A A +A + G TPLH AA N K
Sbjct: 563 GFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKN----------GLTPLHVAAHYDNQKVA 612
Query: 99 QILLSKGATRMALNCNGWLPLDVA 122
+LL KGA+ A NG+ PL +A
Sbjct: 613 LLLLEKGASPHATAKNGYTPLHIA 636
Score = 48.9 bits (115), Expect = 2e-05
Identities = 30/87 (34%), Positives = 45/87 (51%), Gaps = 10/87 (11%)
Query: 40 ITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCCQ 99
+TALH+AA G++ +LLLD AN +A + G TPLH A +K +
Sbjct: 366 LTALHVAAHCGHYRVTKLLLDKRANPNARALN----------GFTPLHIACKKNRIKVME 415
Query: 100 ILLSKGATRMALNCNGWLPLDVARMWG 126
+L+ GA+ A+ +G P+ VA G
Sbjct: 416 LLVKYGASIQAITESGLTPIHVAAFMG 442
Score = 48.5 bits (114), Expect = 3e-05
Identities = 41/126 (32%), Positives = 51/126 (39%), Gaps = 24/126 (19%)
Query: 33 NKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIG------------ 80
N G+T LH+A+ G+ D V LLLD AN +T TS+ L
Sbjct: 656 NIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILT 715
Query: 81 -----------AGSTPLHYAACGGNLKCCQILLSKGATRMALNCNGWLPLDVARMWGR-H 128
G TPL A GN+K LL +GA A NG+ PL A G H
Sbjct: 716 KHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTH 775
Query: 129 WLEPLL 134
+ LL
Sbjct: 776 IINVLL 781
Score = 46.6 bits (109), Expect = 1e-04
Identities = 29/91 (31%), Positives = 46/91 (49%), Gaps = 10/91 (10%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
+N G+ ALH+AA G+ VQ LL ++ +AT G+T LH A+
Sbjct: 57 INTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKK----------GNTALHIASL 106
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVA 122
G + ++L+ +GA A + NG+ PL +A
Sbjct: 107 AGQAEVVKVLVKEGANINAQSQNGFTPLYMA 137
Score = 45.8 bits (107), Expect = 2e-04
Identities = 33/104 (31%), Positives = 47/104 (44%), Gaps = 12/104 (11%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGA-GSTPLHYAA 90
VN+T ++G T LH+AA G N N + + G ++D G TPLH A+
Sbjct: 226 VNRTTESGFTPLHIAAHYG-----------NVNVATLLLNRGAAVDFTARNGITPLHVAS 274
Query: 91 CGGNLKCCQILLSKGATRMALNCNGWLPLDVARMWGRHWLEPLL 134
GN ++LL +G A +G PL A G + LL
Sbjct: 275 KRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELL 318
Score = 45.8 bits (107), Expect = 2e-04
Identities = 31/86 (36%), Positives = 41/86 (47%), Gaps = 10/86 (11%)
Query: 41 TALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCCQI 100
T LH+A+ G + VQLLL A+ AAT + G TPLH +A G + +
Sbjct: 499 TPLHIASRLGKTEIVQLLLQHMAHPDAATTN----------GYTPLHISAREGQVDVASV 548
Query: 101 LLSKGATRMALNCNGWLPLDVARMWG 126
LL GA G+ PL VA +G
Sbjct: 549 LLEAGAAHSLATKKGFTPLHVAAKYG 574
Score = 43.5 bits (101), Expect = 9e-04
Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 10/84 (11%)
Query: 39 GITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCC 98
G++ LHMAA + +CV+ LL A T Y T LH AA G+ +
Sbjct: 332 GLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDY----------LTALHVAAHCGHYRVT 381
Query: 99 QILLSKGATRMALNCNGWLPLDVA 122
++LL K A A NG+ PL +A
Sbjct: 382 KLLLDKRANPNARALNGFTPLHIA 405
Score = 40.8 bits (94), Expect = 0.006
Identities = 34/101 (33%), Positives = 49/101 (47%), Gaps = 11/101 (10%)
Query: 34 KTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGG 93
KT D G+T LH AA +G+ V+LLL+ A A T + G +PLH AA G
Sbjct: 295 KTRD-GLTPLHCAARSGHDQVVELLLERGAPLLARTKN----------GLSPLHMAAQGD 343
Query: 94 NLKCCQILLSKGATRMALNCNGWLPLDVARMWGRHWLEPLL 134
+++C + LL A + + L VA G + + LL
Sbjct: 344 HVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLL 384
Score = 39.7 bits (91), Expect = 0.013
Identities = 29/103 (28%), Positives = 44/103 (42%), Gaps = 10/103 (9%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
+ ++G+T +H+AA G+ + V LLL A+ G T LH AA
Sbjct: 424 IQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIR----------GETALHMAAR 473
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVARMWGRHWLEPLL 134
G ++ + LL GA A PL +A G+ + LL
Sbjct: 474 AGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLL 516
Score = 39.7 bits (91), Expect = 0.013
Identities = 32/102 (31%), Positives = 44/102 (42%), Gaps = 12/102 (11%)
Query: 28 LSKFVNKTADA--GITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTP 85
L K N A A G T LH+A ++LL+ A+ A T +G TP
Sbjct: 385 LDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAIT----------ESGLTP 434
Query: 86 LHYAACGGNLKCCQILLSKGATRMALNCNGWLPLDVARMWGR 127
+H AA G+L +LL GA+ N G L +A G+
Sbjct: 435 IHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQ 476
Score = 38.9 bits (89), Expect = 0.021
Identities = 40/143 (27%), Positives = 60/143 (40%), Gaps = 15/143 (10%)
Query: 39 GITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCC 98
G T L +A G V LL AN +A T + G TPLH AA G+
Sbjct: 728 GYTPLIVACHYGNVKMVNFLLKQGANVNAKTKN----------GYTPLHQAAQQGHTHII 777
Query: 99 QILLSKGATRMALNCNGWLPLDVARMWGRHWLEPLLAPSSDTIVSSFPT---SNYLLLP- 154
+LL GA A NG L +A+ G + L ++ + ++ T + L +P
Sbjct: 778 NVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPE 837
Query: 155 -LMSVLNIAREYGLHSPTTSSNE 176
+ VL+++ E G + T E
Sbjct: 838 TMTEVLDVSDEEGDDTMTGDGGE 860
Score = 38.5 bits (88), Expect = 0.028
Identities = 30/89 (33%), Positives = 39/89 (43%), Gaps = 10/89 (11%)
Query: 39 GITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCC 98
G TALHMAA G + V+ LL A A TPLH A+ G +
Sbjct: 464 GETALHMAARAGQVEVVRCLLRNGALVDARAREE----------QTPLHIASRLGKTEIV 513
Query: 99 QILLSKGATRMALNCNGWLPLDVARMWGR 127
Q+LL A A NG+ PL ++ G+
Sbjct: 514 QLLLQHMAHPDAATTNGYTPLHISAREGQ 542
Score = 37.7 bits (86), Expect = 0.048
Identities = 34/97 (35%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 40 ITALHMAALNGYFDCVQLLL--DLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKC 97
+ ALH+AA LLL D NA+ + T+ +G TPLH AA GN+
Sbjct: 193 LPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTE----SGFTPLHIAAHYGNVNV 248
Query: 98 CQILLSKGATRMALNCNGWLPLDVARMWGRHWLEPLL 134
+LL++GA NG PL VA G + LL
Sbjct: 249 ATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLL 285
Score = 36.6 bits (83), Expect = 0.11
Identities = 28/81 (34%), Positives = 38/81 (46%), Gaps = 13/81 (16%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
+N + G T L+MAA + D V+ LL+ AN S AT G TPL A
Sbjct: 123 INAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATED----------GFTPLAVALQ 172
Query: 92 GGNLKCCQILL---SKGATRM 109
G+ + ILL +KG R+
Sbjct: 173 QGHNQAVAILLENDTKGKVRL 193
>RFXK_MOUSE (Q9Z205) DNA-binding protein RFXANK (Regulatory factor X
subunit B) (RFX-B) (Regulatory factor X-associated
ankyrin-containing protein) (Ankyrin repeat-containing
adapter protein Tvl-1)
Length = 269
Score = 50.8 bits (120), Expect = 5e-06
Identities = 28/82 (34%), Positives = 47/82 (57%), Gaps = 10/82 (12%)
Query: 41 TALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCCQI 100
+AL +A++ GY D V+LLLD + + + ++ G TPL YA G ++KC +
Sbjct: 168 SALSLASMGGYTDIVRLLLDRDVDINIYDWN----------GGTPLLYAVRGNHVKCVEA 217
Query: 101 LLSKGATRMALNCNGWLPLDVA 122
LL++GA +G+ P+D+A
Sbjct: 218 LLARGADLTTEADSGYTPMDLA 239
>LCTA_LATMA (Q9XZC0) Alpha-latrocrustotoxin (Alpha-LCT) (Crusta1)
Length = 1395
Score = 50.4 bits (119), Expect = 7e-06
Identities = 34/113 (30%), Positives = 54/113 (47%), Gaps = 10/113 (8%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
V++ G TALH+A +N + Q L+ AN +A T GSTPLH+AA
Sbjct: 742 VDQETANGFTALHLAIMNPNTETPQFLIAKGANINAKT----------NDGSTPLHFAAA 791
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVARMWGRHWLEPLLAPSSDTIVSS 144
G Q+L+ KGA A N +P+ A + G + +L +++++
Sbjct: 792 LGKTNIFQLLMDKGANIKAENLINQMPIHEAVVNGHLAIVKMLIEQDSSLMNA 844
Score = 38.1 bits (87), Expect = 0.036
Identities = 26/93 (27%), Positives = 40/93 (42%), Gaps = 10/93 (10%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
+N +++G+T LH+A L ++L+ N MD G TPLHYA+
Sbjct: 605 INIKSNSGLTPLHLAVLQNNLSAAKVLVKSNKKVKL------NEMD--NNGMTPLHYASM 656
Query: 92 GGNLKCCQILLSKGA--TRMALNCNGWLPLDVA 122
GNL+ + S+ W PL +A
Sbjct: 657 LGNLEFVKYFTSEQGIDVNAKTKVKNWTPLHLA 689
Score = 36.2 bits (82), Expect = 0.14
Identities = 31/96 (32%), Positives = 40/96 (41%), Gaps = 19/96 (19%)
Query: 34 KTADAGITALHMAALNGYFDCVQLLL-----DLNANASAATYHYGTSMDLIGAGSTPLHY 88
KT T LH+A L FD Q LL D++ A A TPLH
Sbjct: 677 KTKVKNWTPLHLAILFKKFDVAQSLLQVRNIDISTRADQAI--------------TPLHL 722
Query: 89 AACGGNLKCCQILLSKGATRMALNCNGWLPLDVARM 124
AA GN + + +L+ GA NG+ L +A M
Sbjct: 723 AAATGNSQIVKTILNSGAVVDQETANGFTALHLAIM 758
>RIK4_HUMAN (P57078) Serine/threonine-protein kinase RIPK4 (EC
2.7.1.37) (Receptor-interacting serine-threonine kinase
4) (Ankyrin repeat domain protein 3)
(PKC-delta-interacting protein kinase)
Length = 832
Score = 50.1 bits (118), Expect = 9e-06
Identities = 46/166 (27%), Positives = 69/166 (40%), Gaps = 20/166 (12%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
VN + TALH AA NG +LLL+ NA+ + + G TP+H A
Sbjct: 545 VNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFE----------GRTPMHVACQ 594
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVARMWGRHWLEPLLAPSSDTIVSSFPTSNYL 151
G +ILL +G + WLPL A G + LLA V N
Sbjct: 595 HGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSV------NAQ 648
Query: 152 LLPLMSVLNIAREYGLHSPT----TSSNEIDFCAVCLERPCTVAAE 193
L + L++A + G + ++++ C++ + P VAAE
Sbjct: 649 TLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAE 694
Score = 45.8 bits (107), Expect = 2e-04
Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 10/121 (8%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
VN G T LH+AA G++ ++L+DL ++ + + TPLH AA
Sbjct: 645 VNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSL----------LAQTPLHVAAE 694
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVARMWGRHWLEPLLAPSSDTIVSSFPTSNYL 151
G+ ++LL +GA + A+ +G+ L +A G LL +++ P +
Sbjct: 695 TGHTSTARLLLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTA 754
Query: 152 L 152
L
Sbjct: 755 L 755
Score = 35.4 bits (80), Expect = 0.24
Identities = 39/147 (26%), Positives = 64/147 (43%), Gaps = 21/147 (14%)
Query: 27 ELSKFVNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGS-TP 85
E + VN+ G T +H+A +G + V++LL G + L G + P
Sbjct: 573 EKNASVNEVDFEGRTPMHVACQHGQENIVRILL-----------RRGVDVSLQGKDAWLP 621
Query: 86 LHYAACGGNLKCCQILLSK-GATRMALNCNGWLPLDVARMWGRHWLEPLLAPSSDTIVSS 144
LHYAA G+L ++L + G + A +G PL +A G + + +L +
Sbjct: 622 LHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDV--- 678
Query: 145 FPTSNYLLLPLMSVLNIAREYGLHSPT 171
N L + L++A E G H+ T
Sbjct: 679 ----NVCSLLAQTPLHVAAETG-HTST 700
Score = 35.0 bits (79), Expect = 0.31
Identities = 31/119 (26%), Positives = 51/119 (42%), Gaps = 23/119 (19%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSM------------DLI 79
V+ D+G + LH+A G +C + LL NAN + + T + +L+
Sbjct: 479 VDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELL 538
Query: 80 GAGS-----------TPLHYAACGGNLKCCQILLSKGATRMALNCNGWLPLDVARMWGR 127
A T LH+AA G+ ++LL K A+ ++ G P+ VA G+
Sbjct: 539 LARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQ 597
Score = 33.9 bits (76), Expect = 0.69
Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 22/90 (24%)
Query: 39 GITALHMAALNGYFDCVQLLLDLNANA-------------SAATYHYGTSMDLIGA---- 81
G TALH+AA NG+ V+LL++ A+ +AA H +L+ A
Sbjct: 718 GYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVSADVID 777
Query: 82 -----GSTPLHYAACGGNLKCCQILLSKGA 106
G + LH AA G + + + LL GA
Sbjct: 778 LFDEQGLSALHLAAQGRHAQTVETLLRHGA 807
Score = 32.3 bits (72), Expect = 2.0
Identities = 26/84 (30%), Positives = 37/84 (43%), Gaps = 10/84 (11%)
Query: 27 ELSKFVNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPL 86
+L VN + T LH+AA G+ +LLL A A T G T L
Sbjct: 673 DLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAMT----------SDGYTAL 722
Query: 87 HYAACGGNLKCCQILLSKGATRMA 110
H AA G+L ++L+ + A +A
Sbjct: 723 HLAARNGHLATVKLLVEEKADVLA 746
>PSDA_HUMAN (O75832) 26S proteasome non-ATPase regulatory subunit 10
(26S proteasome regulatory subunit p28) (Gankyrin)
Length = 226
Score = 50.1 bits (118), Expect = 9e-06
Identities = 41/132 (31%), Positives = 54/132 (40%), Gaps = 14/132 (10%)
Query: 7 CFNNLCILYSCYSFTSCRCSEL----SKFVNKTADAGITALHMAALNGYFDCVQLLLDLN 62
C +NL + YS E +T TALH A G+ + V+ LL L
Sbjct: 4 CVSNLMVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLG 63
Query: 63 ANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCCQILLSKGATRMALNCNGWLPLDVA 122
+ D AG +PLH AA G + + LL KGA A+N NG PL A
Sbjct: 64 VPVN----------DKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYA 113
Query: 123 RMWGRHWLEPLL 134
RH + +L
Sbjct: 114 ASKNRHEIAVML 125
Score = 37.0 bits (84), Expect = 0.081
Identities = 31/115 (26%), Positives = 46/115 (39%), Gaps = 23/115 (20%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGA---------- 81
VN G T LH AA + +LL+ AN A ++ T+M A
Sbjct: 99 VNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHIL 158
Query: 82 -------------GSTPLHYAACGGNLKCCQILLSKGATRMALNCNGWLPLDVAR 123
G+TPLH A ++ ++L+S+GA+ N PL VA+
Sbjct: 159 LYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAK 213
>PPGA_MOUSE (Q923M0) Protein phosphatase 1 regulatory inhibitor
subunit 16A (Myosin phosphatase targeting subunit 3)
(Mypt3)
Length = 524
Score = 50.1 bits (118), Expect = 9e-06
Identities = 29/89 (32%), Positives = 47/89 (52%), Gaps = 10/89 (11%)
Query: 33 NKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACG 92
N + G+TALH ++ + + Q LLD A+ +A T PLH AA
Sbjct: 98 NLANEDGLTALHQCCIDDFQEMAQQLLDAGADVNARDSECWT----------PLHAAATC 147
Query: 93 GNLKCCQILLSKGATRMALNCNGWLPLDV 121
G+L ++L+S+GA +A+N +G +P D+
Sbjct: 148 GHLHLVELLISRGADLLAVNSDGNMPYDL 176
Score = 45.1 bits (105), Expect = 3e-04
Identities = 25/64 (39%), Positives = 37/64 (57%), Gaps = 1/64 (1%)
Query: 77 DLIGAGSTPLHYAACGGNLKCCQILLSKGATRMALNCNGWLPLDVARMWGR-HWLEPLLA 135
D + G+T LH AA G + +LL +GA+ A + +GW PL A WG+ H +E L+A
Sbjct: 227 DPLDHGATLLHIAAANGFSEVATLLLEQGASLSAKDHDGWEPLHAAAYWGQVHLVELLVA 286
Query: 136 PSSD 139
+D
Sbjct: 287 HGAD 290
Score = 43.1 bits (100), Expect = 0.001
Identities = 29/85 (34%), Positives = 41/85 (48%), Gaps = 10/85 (11%)
Query: 37 DAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLK 96
D G T LH+AA NG+ + LLL+ A+ SA + G PLH AA G +
Sbjct: 230 DHGATLLHIAAANGFSEVATLLLEQGASLSAKDHD----------GWEPLHAAAYWGQVH 279
Query: 97 CCQILLSKGATRMALNCNGWLPLDV 121
++L++ GA + PLDV
Sbjct: 280 LVELLVAHGADLNGKSLVDETPLDV 304
>PPGA_HUMAN (Q96I34) Protein phosphatase 1 regulatory inhibitor
subunit 16A
Length = 528
Score = 49.7 bits (117), Expect = 1e-05
Identities = 28/83 (33%), Positives = 45/83 (53%), Gaps = 10/83 (12%)
Query: 39 GITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCC 98
G+TALH ++ + + VQ LL+ AN +A T PLH AA G+L
Sbjct: 104 GLTALHQCCIDDFREMVQQLLEAGANINACDSECWT----------PLHAAATCGHLHLV 153
Query: 99 QILLSKGATRMALNCNGWLPLDV 121
++L++ GA +A+N +G +P D+
Sbjct: 154 ELLIASGANLLAVNTDGNMPYDL 176
Score = 43.9 bits (102), Expect = 7e-04
Identities = 30/85 (35%), Positives = 41/85 (47%), Gaps = 10/85 (11%)
Query: 37 DAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLK 96
D G T LH+AA NG+ + LLL+ A+ SA G PLH AA G +
Sbjct: 230 DHGATLLHVAAANGFSEAAALLLEHRASLSAKDQD----------GWEPLHAAAYWGQVP 279
Query: 97 CCQILLSKGATRMALNCNGWLPLDV 121
++L++ GA A + PLDV
Sbjct: 280 LVELLVAHGADLNAKSLMDETPLDV 304
Score = 37.7 bits (86), Expect = 0.048
Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 5/99 (5%)
Query: 36 ADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNL 95
AD GIT + A + +++L D+ + A + + G+T LH AA G
Sbjct: 191 ADRGITQDSIEAARAVPE-LRMLDDIRSRLQAGADLHAP----LDHGATLLHVAAANGFS 245
Query: 96 KCCQILLSKGATRMALNCNGWLPLDVARMWGRHWLEPLL 134
+ +LL A+ A + +GW PL A WG+ L LL
Sbjct: 246 EAAALLLEHRASLSAKDQDGWEPLHAAAYWGQVPLVELL 284
>PA26_RAT (P97570) 85 kDa calcium-independent phospholipase A2 (EC
3.1.1.4) (iPLA2) (CaI-PLA2) (Group VI phospholipase A2)
(GVI PLA2)
Length = 751
Score = 49.7 bits (117), Expect = 1e-05
Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 10/91 (10%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
V+ T+ +G TALH+A FDCV +LL ANA A H G+TPLH A
Sbjct: 309 VDSTSASGNTALHVAVTRNRFDCVMVLLTYGANAGARGEH----------GNTPLHLAMS 358
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVA 122
N++ + L+ GA N G P +A
Sbjct: 359 KDNMEMVKALIVFGAEVDTPNDFGETPAFIA 389
Score = 32.7 bits (73), Expect = 1.5
Identities = 19/78 (24%), Positives = 38/78 (48%), Gaps = 11/78 (14%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
+N+ + G+T LH+A G + V++LL NA +++G G P+H A
Sbjct: 212 LNQVNNQGLTPLHLACQMGKQEMVRVLLLCNARC-----------NIMGPGGFPIHTAMK 260
Query: 92 GGNLKCCQILLSKGATRM 109
C ++++S + ++
Sbjct: 261 FSQKGCAEMIISMDSNQI 278
>AN28_HUMAN (O15084) Ankyrin repeat domain protein 28 (Fragment)
Length = 1059
Score = 49.7 bits (117), Expect = 1e-05
Identities = 54/184 (29%), Positives = 80/184 (43%), Gaps = 26/184 (14%)
Query: 35 TADA-GITALHMAALNGYFDCVQLLLD-------------------LNANASAATYHYGT 74
TAD G TALH A NG+ CV+LLL+ +N N AA T
Sbjct: 757 TADNHGYTALHWACYNGHETCVELLLEQEVFQKTEGNAFSPLHCAVINDNEGAAEMLIDT 816
Query: 75 -SMDLIGA----GSTPLHYAACGGNLKCCQILLSKGATRMALNCNGWLPLDVARMWGR-H 128
++ A G TPLH AA +++C Q+LLS A +++ G PL +A G+ +
Sbjct: 817 LGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTN 876
Query: 129 WLEPLLAPSSDTIVSSFPTSNYLLLPLMSVLNIAREYGLHSPTTSSNEIDFCAVCLERPC 188
+E L++ +S + + N L S + + T N I+ L+ P
Sbjct: 877 TVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINATNAALQTPL 936
Query: 189 TVAA 192
VAA
Sbjct: 937 HVAA 940
Score = 47.0 bits (110), Expect = 8e-05
Identities = 28/68 (41%), Positives = 39/68 (57%), Gaps = 10/68 (14%)
Query: 39 GITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCC 98
G+ LH+AAL+G+ DC + LL ++ + T D G T LH AA GGNL+C
Sbjct: 378 GMFPLHLAALSGFSDCCRKLL-------SSGFDIDTPDDF---GRTCLHAAAAGGNLECL 427
Query: 99 QILLSKGA 106
+LL+ GA
Sbjct: 428 NLLLNTGA 435
Score = 46.2 bits (108), Expect = 1e-04
Identities = 30/86 (34%), Positives = 40/86 (45%), Gaps = 10/86 (11%)
Query: 37 DAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLK 96
D G T LH AA G +C+ LLL+ A+ + G +PLHYAA N +
Sbjct: 409 DFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKF----------GRSPLHYAAANCNYQ 458
Query: 97 CCQILLSKGATRMALNCNGWLPLDVA 122
C L+ GA+ L+ G PL A
Sbjct: 459 CLFALVGSGASVNDLDERGCTPLHYA 484
Score = 43.9 bits (102), Expect = 7e-04
Identities = 41/126 (32%), Positives = 54/126 (42%), Gaps = 27/126 (21%)
Query: 24 RCSE----LSKFVNKTADAGITALHMAALNGYFDCVQLLLDLNANASA------ATYHYG 73
+C+E L VN + AG TALH AA +G+ + V+LLL AN +A H+
Sbjct: 127 KCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWA 186
Query: 74 TSMD-------LIGAGS----------TPLHYAACGGNLKCCQILLSKGATRMALNCNGW 116
M L+ G+ TPLH AA G + + LL G N G
Sbjct: 187 AYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGN 246
Query: 117 LPLDVA 122
PL VA
Sbjct: 247 TPLHVA 252
Score = 43.9 bits (102), Expect = 7e-04
Identities = 27/86 (31%), Positives = 38/86 (43%), Gaps = 10/86 (11%)
Query: 29 SKFVNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHY 88
+ VN T G T LH AA + +C+QLLL NA ++ G TPL
Sbjct: 819 ASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVD----------STGKTPLMM 868
Query: 89 AACGGNLKCCQILLSKGATRMALNCN 114
AA G ++L+S + + L N
Sbjct: 869 AAENGQTNTVEMLVSSASAELTLQDN 894
Score = 43.9 bits (102), Expect = 7e-04
Identities = 37/138 (26%), Positives = 59/138 (41%), Gaps = 15/138 (10%)
Query: 8 FNNLCILYSCYSFTSCRCSEL---SKFVNKTADAGITALHMAALNGYFD-CVQLLLDLNA 63
+ N + +CY+ +EL VN+ + G T LH AA + + C++LL+ A
Sbjct: 244 YGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGA 303
Query: 64 NASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCCQILLSKGATRMALNCNGWLPLDVAR 123
+ + + G TPLH A G Q ++ GA + NG PL +A
Sbjct: 304 DVNMKSKD----------GKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAA 353
Query: 124 MWGRHWL-EPLLAPSSDT 140
+G L L+ +DT
Sbjct: 354 RYGHELLINTLITSGADT 371
Score = 41.6 bits (96), Expect = 0.003
Identities = 28/88 (31%), Positives = 39/88 (43%), Gaps = 10/88 (11%)
Query: 39 GITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCC 98
G T L ++ LNG+ DCV LL+ AN A G T LH A G+ +C
Sbjct: 659 GQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKW----------GRTALHRGAVTGHEECV 708
Query: 99 QILLSKGATRMALNCNGWLPLDVARMWG 126
LL GA + + G P+ ++ G
Sbjct: 709 DALLQHGAKCLLRDSRGRTPIHLSAACG 736
Score = 40.8 bits (94), Expect = 0.006
Identities = 37/114 (32%), Positives = 48/114 (41%), Gaps = 27/114 (23%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLL-------LDLNANASAATYHYG----------- 73
VN G T L MAA NG + V++L L L N+ H
Sbjct: 855 VNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALL 914
Query: 74 -----TSMDLIGAGS----TPLHYAACGGNLKCCQILLSKGATRMALNCNGWLP 118
T +LI A + TPLH AA G Q LL KGA+ +A++ NG+ P
Sbjct: 915 ILEKITDRNLINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTP 968
Score = 40.0 bits (92), Expect = 0.010
Identities = 29/95 (30%), Positives = 41/95 (42%), Gaps = 10/95 (10%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
VN + G T LHM AL+G F Q ++ A + G+TPLH AA
Sbjct: 305 VNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKN----------GNTPLHIAAR 354
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVARMWG 126
G+ L++ GA +G PL +A + G
Sbjct: 355 YGHELLINTLITSGADTAKRGIHGMFPLHLAALSG 389
Score = 38.9 bits (89), Expect = 0.021
Identities = 26/87 (29%), Positives = 37/87 (41%), Gaps = 18/87 (20%)
Query: 41 TALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCCQI 100
T +H AA NG+ +C++LL+ +A G G TPL + G+ C
Sbjct: 625 TPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGN-------GQTPLMLSVLNGHTDCVYS 677
Query: 101 LLSKGATRMALNCNGWLPLDVARMWGR 127
LL+KGA +D WGR
Sbjct: 678 LLNKGAN-----------VDAKDKWGR 693
Score = 37.7 bits (86), Expect = 0.048
Identities = 25/74 (33%), Positives = 39/74 (51%), Gaps = 18/74 (24%)
Query: 38 AGITALHMAALNGYFDC----VQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGG 93
A I+ LH+AA +G+ VQ LLDL+ S+ G TPL AA G
Sbjct: 555 ATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSS--------------GRTPLDLAAFKG 600
Query: 94 NLKCCQILLSKGAT 107
+++C +L+++GA+
Sbjct: 601 HVECVDVLINQGAS 614
Score = 37.7 bits (86), Expect = 0.048
Identities = 23/66 (34%), Positives = 35/66 (52%), Gaps = 10/66 (15%)
Query: 41 TALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCCQI 100
T LH+AA N C + L+ L +N + + AG T LH+AA G+ + ++
Sbjct: 115 TPLHIAAANKAVKCAEALVPLLSNVNVSD----------RAGRTALHHAAFSGHGEMVKL 164
Query: 101 LLSKGA 106
LLS+GA
Sbjct: 165 LLSRGA 170
Score = 35.8 bits (81), Expect = 0.18
Identities = 30/104 (28%), Positives = 44/104 (41%), Gaps = 11/104 (10%)
Query: 33 NKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACG 92
NK G + LH AA N + C+ L+ A+ + DL G TPLHYAA
Sbjct: 438 NKKDKFGRSPLHYAAANCNYQCLFALVGSGASVN----------DLDERGCTPLHYAATS 487
Query: 93 G-NLKCCQILLSKGATRMALNCNGWLPLDVARMWGRHWLEPLLA 135
+ KC + LL A + G+ + + +G L+A
Sbjct: 488 DTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIA 531
Score = 31.2 bits (69), Expect = 4.5
Identities = 21/71 (29%), Positives = 33/71 (45%), Gaps = 10/71 (14%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
VN +T LH A + + VQ+LL +A+ +A ++ TPLH AA
Sbjct: 73 VNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNW----------QTPLHIAAA 122
Query: 92 GGNLKCCQILL 102
+KC + L+
Sbjct: 123 NKAVKCAEALV 133
Score = 31.2 bits (69), Expect = 4.5
Identities = 36/126 (28%), Positives = 54/126 (42%), Gaps = 22/126 (17%)
Query: 15 YSCYSFTSCRCSELSKFVNKTADAGI------TALHMAALNGYFDCVQLL-----LDLNA 63
Y+ S T +C E + A+ GI A+H +A G+ C+QL+ LD+
Sbjct: 483 YAATSDTDGKCLEY--LLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLM 540
Query: 64 NASAATYHYGTSMDLIG---AGSTPLHYAACGGNLKCCQILLSKGATRMALNCNGWLPLD 120
S GT M A +PLH AA G+ + ++L+ N +G PLD
Sbjct: 541 ETS------GTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLD 594
Query: 121 VARMWG 126
+A G
Sbjct: 595 LAAFKG 600
>ANK3_HUMAN (Q12955) Ankyrin 3 (ANK-3) (Ankyrin G)
Length = 4377
Score = 49.3 bits (116), Expect = 2e-05
Identities = 30/87 (34%), Positives = 45/87 (51%), Gaps = 10/87 (11%)
Query: 40 ITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCCQ 99
+TALH+AA G++ ++LLD AN +A + G TPLH A +K +
Sbjct: 368 LTALHVAAHCGHYKVAKVLLDKKANPNAKALN----------GFTPLHIACKKNRIKVME 417
Query: 100 ILLSKGATRMALNCNGWLPLDVARMWG 126
+LL GA+ A+ +G P+ VA G
Sbjct: 418 LLLKHGASIQAVTESGLTPIHVAAFMG 444
Score = 48.9 bits (115), Expect = 2e-05
Identities = 33/90 (36%), Positives = 42/90 (46%), Gaps = 10/90 (11%)
Query: 33 NKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACG 92
N +G T LH++A G+ D LLD A+ S T G TPLH AA
Sbjct: 526 NAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITT----------KKGFTPLHVAAKY 575
Query: 93 GNLKCCQILLSKGATRMALNCNGWLPLDVA 122
G L+ +LL K A+ A +G PL VA
Sbjct: 576 GKLEVANLLLQKSASPDAAGKSGLTPLHVA 605
Score = 48.9 bits (115), Expect = 2e-05
Identities = 35/88 (39%), Positives = 44/88 (49%), Gaps = 10/88 (11%)
Query: 35 TADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGN 94
T G T LH+AA G + LLL +A+ AA G S G TPLH AA N
Sbjct: 561 TTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAA----GKS------GLTPLHVAAHYDN 610
Query: 95 LKCCQILLSKGATRMALNCNGWLPLDVA 122
K +LL +GA+ A NG+ PL +A
Sbjct: 611 QKVALLLLDQGASPHAAAKNGYTPLHIA 638
Score = 48.5 bits (114), Expect = 3e-05
Identities = 31/84 (36%), Positives = 40/84 (46%), Gaps = 10/84 (11%)
Query: 39 GITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCC 98
G++ LHMA + +CVQLLL N T Y T LH AA G+ K
Sbjct: 334 GLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDY----------LTALHVAAHCGHYKVA 383
Query: 99 QILLSKGATRMALNCNGWLPLDVA 122
++LL K A A NG+ PL +A
Sbjct: 384 KVLLDKKANPNAKALNGFTPLHIA 407
Score = 48.5 bits (114), Expect = 3e-05
Identities = 30/91 (32%), Positives = 46/91 (49%), Gaps = 10/91 (10%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
+N G+ ALH+A+ G+ + V LL AN AAT G+T LH A+
Sbjct: 67 INICNQNGLNALHLASKEGHVEVVSELLQREANVDAAT----------KKGNTALHIASL 116
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVA 122
G + ++L++ GA A + NG+ PL +A
Sbjct: 117 AGQAEVVKVLVTNGANVNAQSQNGFTPLYMA 147
Score = 48.5 bits (114), Expect = 3e-05
Identities = 31/94 (32%), Positives = 46/94 (47%), Gaps = 10/94 (10%)
Query: 33 NKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACG 92
N GI ++H+AA G+ D V LLL NAN + + +G TPLH AA
Sbjct: 658 NAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSN----------KSGLTPLHLAAQE 707
Query: 93 GNLKCCQILLSKGATRMALNCNGWLPLDVARMWG 126
+ ++L+++GA A G+ PL V +G
Sbjct: 708 DRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYG 741
Score = 47.0 bits (110), Expect = 8e-05
Identities = 33/103 (32%), Positives = 52/103 (50%), Gaps = 10/103 (9%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
V+ G TALH+A+L G + V++L+ AN +A + + G TPL+ AA
Sbjct: 100 VDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQN----------GFTPLYMAAQ 149
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVARMWGRHWLEPLL 134
+L+ + LL GA++ +G+ PL VA G + LL
Sbjct: 150 ENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLL 192
Score = 45.1 bits (105), Expect = 3e-04
Identities = 40/136 (29%), Positives = 58/136 (42%), Gaps = 19/136 (13%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
VN + +G+T LH+AA + ++L++ A+ A T G TPLH
Sbjct: 690 VNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQT----------KMGYTPLHVGCH 739
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVARMWGR-HWLEPLLAPSSDTIVSSFPTSNY 150
GN+K LL A A NG+ PL A G H + LL ++ + N
Sbjct: 740 YGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNA--------SPNE 791
Query: 151 LLLPLMSVLNIAREYG 166
L + + L IAR G
Sbjct: 792 LTVNGNTALGIARRLG 807
Score = 45.1 bits (105), Expect = 3e-04
Identities = 34/98 (34%), Positives = 46/98 (46%), Gaps = 10/98 (10%)
Query: 41 TALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCCQI 100
T LH++A G D VQ LL A+ +AAT +G TPLH +A G+
Sbjct: 501 TPLHISARLGKADIVQQLLQQGASPNAATT----------SGYTPLHLSAREGHEDVAAF 550
Query: 101 LLSKGATRMALNCNGWLPLDVARMWGRHWLEPLLAPSS 138
LL GA+ G+ PL VA +G+ + LL S
Sbjct: 551 LLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKS 588
Score = 44.7 bits (104), Expect = 4e-04
Identities = 32/91 (35%), Positives = 45/91 (49%), Gaps = 10/91 (10%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
V+ TA IT LH+A+ G + V+LLLD A A T G TPLH A
Sbjct: 261 VDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRD----------GLTPLHCGAR 310
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVA 122
G+ + ++LL + A ++ NG PL +A
Sbjct: 311 SGHEQVVEMLLDRAAPILSKTKNGLSPLHMA 341
Score = 41.2 bits (95), Expect = 0.004
Identities = 31/94 (32%), Positives = 42/94 (43%), Gaps = 10/94 (10%)
Query: 33 NKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACG 92
N T G TALHMAA +G + V+ L+ A A TPLH +A
Sbjct: 460 NTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKD----------DQTPLHISARL 509
Query: 93 GNLKCCQILLSKGATRMALNCNGWLPLDVARMWG 126
G Q LL +GA+ A +G+ PL ++ G
Sbjct: 510 GKADIVQQLLQQGASPNAATTSGYTPLHLSAREG 543
Score = 40.4 bits (93), Expect = 0.007
Identities = 36/147 (24%), Positives = 55/147 (36%), Gaps = 24/147 (16%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
V+ G T LH+ G V LL +A +A T + G TPLH AA
Sbjct: 723 VDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKN----------GYTPLHQAAQ 772
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVARMWGRHWLEPLLAPSSDTIVSSFPTSNYL 151
G+ +LL A+ L NG L +AR G +S T +
Sbjct: 773 QGHTHIINVLLQNNASPNELTVNGNTALGIARRLG--------------YISVVDTLKIV 818
Query: 152 LLPLMSVLNIAREYGLHSPTTSSNEID 178
M+ + ++ ++ P T + +D
Sbjct: 819 TEETMTTTTVTEKHKMNVPETMNEVLD 845
Score = 38.9 bits (89), Expect = 0.021
Identities = 32/106 (30%), Positives = 47/106 (44%), Gaps = 10/106 (9%)
Query: 38 AGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKC 97
+G T LH+AA G + LLL+ AA + D+ TPLH A+ GN
Sbjct: 234 SGFTPLHIAAHYGNINVATLLLN-----RAAAVDFTARNDI-----TPLHVASKRGNANM 283
Query: 98 CQILLSKGATRMALNCNGWLPLDVARMWGRHWLEPLLAPSSDTIVS 143
++LL +GA A +G PL G + +L + I+S
Sbjct: 284 VKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILS 329
Score = 36.2 bits (82), Expect = 0.14
Identities = 25/97 (25%), Positives = 43/97 (43%), Gaps = 12/97 (12%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGA-GSTPLHYAA 90
+ ++G+T +H+AA G+ + V L+ H+G S + G T LH AA
Sbjct: 426 IQAVTESGLTPIHVAAFMGHVNIVSQLM-----------HHGASPNTTNVRGETALHMAA 474
Query: 91 CGGNLKCCQILLSKGATRMALNCNGWLPLDVARMWGR 127
G + + L+ GA A + PL ++ G+
Sbjct: 475 RSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGK 511
Score = 33.1 bits (74), Expect = 1.2
Identities = 28/89 (31%), Positives = 37/89 (41%), Gaps = 10/89 (11%)
Query: 38 AGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKC 97
+G+T LH+AA LLLD A+ AA + G TPLH AA +
Sbjct: 597 SGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKN----------GYTPLHIAAKKNQMDI 646
Query: 98 CQILLSKGATRMALNCNGWLPLDVARMWG 126
LL GA A+ G + +A G
Sbjct: 647 ATTLLEYGADANAVTRQGIASVHLAAQEG 675
>PSDA_MOUSE (Q9Z2X2) 26S proteasome non-ATPase regulatory subunit 10
(26S proteasome regulatory subunit p28) (Gankyrin)
Length = 231
Score = 48.9 bits (115), Expect = 2e-05
Identities = 41/132 (31%), Positives = 54/132 (40%), Gaps = 14/132 (10%)
Query: 7 CFNNLCILYSCYSFTSCRCSEL----SKFVNKTADAGITALHMAALNGYFDCVQLLLDLN 62
C +N+ I YS E +T TALH A G+ + V+ LL L
Sbjct: 4 CVSNIMICNLAYSGKLDELKERILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLG 63
Query: 63 ANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCCQILLSKGATRMALNCNGWLPLDVA 122
+ D AG +PLH AA G + + LL KGA A+N NG PL A
Sbjct: 64 VPVN----------DKDDAGWSPLHIAASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYA 113
Query: 123 RMWGRHWLEPLL 134
RH + +L
Sbjct: 114 ASKNRHEIAVML 125
Score = 38.9 bits (89), Expect = 0.021
Identities = 30/91 (32%), Positives = 39/91 (41%), Gaps = 10/91 (10%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
VN G T LH AA + +LL+ AN A ++ T+M H AA
Sbjct: 99 VNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYDATAM----------HRAAA 148
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVA 122
GNLK ILL A+ + G PL +A
Sbjct: 149 KGNLKMVHILLFYKASTNIQDTEGNTPLHLA 179
>LATA_LATMA (P23631) Alpha-latrotoxin precursor (Alpha-LTX)
Length = 1401
Score = 48.5 bits (114), Expect = 3e-05
Identities = 30/95 (31%), Positives = 46/95 (47%), Gaps = 10/95 (10%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
+ + D T LH+AA++ Y + +Q+LLD +N A T +G+TPLH A
Sbjct: 756 IEQKTDEKYTPLHLAAMSKYPELIQILLDQGSNFEAKT----------NSGATPLHLATF 805
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVARMWG 126
G + ILL+ + NG +P+ A M G
Sbjct: 806 KGKSQAALILLNNEVNWRDTDENGQMPIHGAAMTG 840
Score = 43.1 bits (100), Expect = 0.001
Identities = 31/96 (32%), Positives = 42/96 (43%), Gaps = 10/96 (10%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
VN A GIT LH+A + G + L+ D+ N T TPLH AA
Sbjct: 723 VNLKALGGITPLHLAVIQGRKQILSLMFDIGVNIEQKT----------DEKYTPLHLAAM 772
Query: 92 GGNLKCCQILLSKGATRMALNCNGWLPLDVARMWGR 127
+ QILL +G+ A +G PL +A G+
Sbjct: 773 SKYPELIQILLDQGSNFEAKTNSGATPLHLATFKGK 808
Score = 38.9 bits (89), Expect = 0.021
Identities = 41/152 (26%), Positives = 65/152 (41%), Gaps = 14/152 (9%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAAC 91
+N+ G T +H+AA +G V LL+ + ++ TYH+ TPLH AA
Sbjct: 519 LNQPDKKGYTPIHVAADSGNAGIVNLLIQRGVSINSKTYHF---------LQTPLHLAAQ 569
Query: 92 GGNLKCCQILLSKGATRM-ALNCNGWLPLDVARMWGRHWLEPLLAPSSDTIVSSFPTSNY 150
G + Q L+ + + +G+ PL A G LE L S + + SN
Sbjct: 570 RGFVTTFQRLMESPEININERDKDGFTPLHYAIRGGERILEAFLNQISIDVNAK---SNT 626
Query: 151 LLLPLMSVLNIAREYGLHSPTTSSNEIDFCAV 182
L P + I ++ + S S ++D AV
Sbjct: 627 GLTPFHLAI-IKNDWPVASTLLGSKKVDINAV 657
Score = 32.7 bits (73), Expect = 1.5
Identities = 30/120 (25%), Positives = 47/120 (39%), Gaps = 28/120 (23%)
Query: 32 VNKTADAGITALHMAALNGYFDCVQLLLDL---NANASA-----ATYHY----------- 72
+N + ITALH AA+ GY + + L++L NAN + + HY
Sbjct: 654 INAVDENNITALHYAAILGYLETTKQLINLKEINANVVSSPGLLSALHYAILYKHDDVAS 713
Query: 73 --------GTSMDLIGAGSTPLHYAACGGNLKCCQILLSKGATRMALNCNGWLPLDVARM 124
++ +G G TPLH A G + ++ G + PL +A M
Sbjct: 714 FLMRSSNVNVNLKALG-GITPLHLAVIQGRKQILSLMFDIGVNIEQKTDEKYTPLHLAAM 772
Score = 30.4 bits (67), Expect = 7.6
Identities = 23/86 (26%), Positives = 38/86 (43%), Gaps = 11/86 (12%)
Query: 35 TADAGITALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGS-TPLHYAACGG 93
T + G +H AA+ G D Q ++ ++A T +D+ S TPL+ AA
Sbjct: 825 TDENGQMPIHGAAMTGLLDVAQAIISIDA----------TVVDIEDKNSDTPLNLAAQNS 874
Query: 94 NLKCCQILLSKGATRMALNCNGWLPL 119
++ + + +GA N G PL
Sbjct: 875 HIDVIKYFIDQGADINTRNKKGLAPL 900
>ASB8_MOUSE (Q91ZT9) Ankyrin repeat and SOCS box protein 8 (ASB-8)
Length = 288
Score = 48.5 bits (114), Expect = 3e-05
Identities = 36/106 (33%), Positives = 45/106 (41%), Gaps = 22/106 (20%)
Query: 43 LHMAALNGYFDCVQLLLDLNANASA------ATYHYGTSMD----------------LIG 80
LH A + DCV+LLL+ A +A HY D L G
Sbjct: 57 LHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAERDEACVEVLLEYGANPNALDG 116
Query: 81 AGSTPLHYAACGGNLKCCQILLSKGATRMALNCNGWLPLDVARMWG 126
TPLH+AA N +C + LL GA+ AL+ N PL A M G
Sbjct: 117 NRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKG 162
Score = 46.2 bits (108), Expect = 1e-04
Identities = 28/79 (35%), Positives = 38/79 (47%), Gaps = 10/79 (12%)
Query: 41 TALHMAALNGYFDCVQLLLDLNANASAATYHYGTSMDLIGAGSTPLHYAACGGNLKCCQI 100
T LH AA +CV+ LL+ A+ +A Y+ TPL +AA GNL+ I
Sbjct: 120 TPLHWAAFKNNAECVRALLESGASVNALDYN----------NDTPLSWAAMKGNLESVSI 169
Query: 101 LLSKGATRMALNCNGWLPL 119
LL GA +N G P+
Sbjct: 170 LLDYGAEVRVINLKGQTPI 188
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.321 0.134 0.434
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,812,334
Number of Sequences: 164201
Number of extensions: 1967536
Number of successful extensions: 5975
Number of sequences better than 10.0: 264
Number of HSP's better than 10.0 without gapping: 152
Number of HSP's successfully gapped in prelim test: 112
Number of HSP's that attempted gapping in prelim test: 4842
Number of HSP's gapped (non-prelim): 822
length of query: 374
length of database: 59,974,054
effective HSP length: 112
effective length of query: 262
effective length of database: 41,583,542
effective search space: 10894888004
effective search space used: 10894888004
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Medicago: description of AC146807.6