BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC146784.6 - phase: 0
(617 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
RN13_MOUSE (O54965) RING finger protein 13 44 0.002
RN13_HUMAN (O43567) RING finger protein 13 42 0.006
SBN1_HUMAN (Q9NY15) Stabilin 1 precursor (FEEL-1 protein) (MS-1 ... 41 0.011
DLL4_HUMAN (Q9NR61) Delta-like protein 4 precursor (Drosophila D... 40 0.014
SBN2_MOUSE (Q8R4U0) Stabilin 2 precursor [Contains: Short form s... 40 0.018
RN13_CHICK (Q90972) RING finger protein 13 (C-RZF) 40 0.018
SBN2_RAT (Q8CFM6) Stabilin 2 precursor (Hyaluronan receptor for ... 40 0.024
C122_HUMAN (Q9BZQ6) Putative alpha-mannosidase C1orf22 (EC 3.2.1.-) 40 0.024
SBN1_MOUSE (Q8R4Y4) Stabilin 1 precursor (FEEL-1 protein) 39 0.031
LDLR_CRIGR (P35950) Low-density lipoprotein receptor precursor (... 39 0.040
YLK2_CAEEL (P41950) Hypothetical protein D1044.2 precursor 38 0.090
LDLR_RAT (P35952) Low-density lipoprotein receptor precursor (LD... 37 0.12
LDLR_MOUSE (P35951) Low-density lipoprotein receptor precursor (... 37 0.12
EFL3_RAT (O88281) Multiple EGF-like-domain protein 3 precursor (... 37 0.12
DLL3_HUMAN (Q9NYJ7) Delta-like protein 3 precursor (Drosophila D... 37 0.12
TSP1_MOUSE (P35441) Thrombospondin 1 precursor 37 0.15
SEN2_HUMAN (Q8NCE0) tRNA-splicing endonuclease subunit SEN2 (EC ... 37 0.15
LI12_CAEEL (P14585) Lin-12 protein precursor 37 0.20
PRKD_MOUSE (P97313) DNA-dependent protein kinase catalytic subun... 36 0.26
NTC4_MOUSE (P31695) Neurogenic locus notch homolog protein 4 pre... 36 0.26
>RN13_MOUSE (O54965) RING finger protein 13
Length = 381
Score = 43.5 bits (101), Expect = 0.002
Identities = 32/92 (34%), Positives = 48/92 (51%), Gaps = 8/92 (8%)
Query: 94 VLVDRGDCYFTLKAWNAQNGGAAAILVADDREETLITMDTPEEGNVVND-DYIEKINIPS 152
VL+ R DC F +K NAQ G A +V + + LI+M + ND D ++KI+IPS
Sbjct: 95 VLIRRLDCNFDIKVLNAQRAGYKAAIVHNVDSDDLISMGS-------NDIDTLKKIDIPS 147
Query: 153 ALISKSLGDRIKKALSDGEMVHINLDWREALP 184
I +S + +K + + HI L +LP
Sbjct: 148 VFIGESSANSLKDEFTYEKGGHIILVPELSLP 179
>RN13_HUMAN (O43567) RING finger protein 13
Length = 381
Score = 41.6 bits (96), Expect = 0.006
Identities = 30/92 (32%), Positives = 48/92 (51%), Gaps = 8/92 (8%)
Query: 94 VLVDRGDCYFTLKAWNAQNGGAAAILVADDREETLITMDTPEEGNVVND-DYIEKINIPS 152
VL+ R DC F +K NAQ G A +V + + LI+M + ND + ++KI+IPS
Sbjct: 95 VLIRRLDCNFDIKVLNAQRAGYKAAIVHNVDSDDLISMGS-------NDIEVLKKIDIPS 147
Query: 153 ALISKSLGDRIKKALSDGEMVHINLDWREALP 184
I +S + +K + + H+ L +LP
Sbjct: 148 VFIGESSANSLKDEFTYEKGGHLILVPEFSLP 179
>SBN1_HUMAN (Q9NY15) Stabilin 1 precursor (FEEL-1 protein) (MS-1
antigen)
Length = 2570
Score = 40.8 bits (94), Expect = 0.011
Identities = 30/104 (28%), Positives = 44/104 (41%), Gaps = 22/104 (21%)
Query: 415 ETNECLENNGGCWKEKSSNITACRDTFRG-RVCVCPVVNNIKFVGDGYTHCEASGTLSCE 473
E + C +GGC S C G R C C ++GDG E + SC
Sbjct: 1455 EVDPCAHGHGGC-----SPHANCTKVAPGQRTCTC----QDGYMGDGELCQEIN---SCL 1502
Query: 474 FNNGGCWKASHGGRLYSAC--HDDYRKGCECPSGFRGDGVRSCE 515
++GGC +++ C + C C G+ GDG+R+CE
Sbjct: 1503 IHHGGC-------HIHAECIPTGPQQVSCSCREGYSGDGIRTCE 1539
Score = 38.5 bits (88), Expect = 0.053
Identities = 35/104 (33%), Positives = 41/104 (38%), Gaps = 19/104 (18%)
Query: 417 NEC-LENNGGCWKEKSSNITACRDTFRGRV-CVCPVVNNIKFVGDGYTHCEASGTLSCEF 474
+EC L+ GGC + C G+ C C + F GDGY + S C
Sbjct: 906 DECELDVRGGCHTD-----ALCSYVGPGQSRCTC----KLGFAGDGY---QCSPIDPCRA 953
Query: 475 NNGGCWKASHGGRLYSACHDDYRKGCECPSGFRGDGVRSCEDCF 518
NGGC HG A R C CP GF GDG D F
Sbjct: 954 GNGGC----HGLATCRAVGGGQRV-CTCPPGFGGDGFSCYGDIF 992
Score = 33.9 bits (76), Expect = 1.3
Identities = 28/109 (25%), Positives = 47/109 (42%), Gaps = 20/109 (18%)
Query: 408 ICLTPDMETNECLENNGGCWKEKSSNITACRDTFRGRVCVCPVVNNIKFVGDGYTHCEAS 467
+C D+ C + +GGC S C C C + GDG++ C A
Sbjct: 2088 VCTVADL----CQDGHGGC-----SEHANCSQVGTMVTCTCLP----DYEGDGWS-CRAR 2133
Query: 468 GTLSCEFNNGGCWKASHGGRLYSACHDDYRKGCECPSGFRGDGVRSCED 516
+ + + GGC + H L + + + CEC +G+ GDG++ E+
Sbjct: 2134 NPCT-DGHRGGC--SEHANCLSTGLNT---RRCECHAGYVGDGLQCLEE 2176
>DLL4_HUMAN (Q9NR61) Delta-like protein 4 precursor (Drosophila
Delta homolog 4) (UNQ1895/PRO4341)
Length = 685
Score = 40.4 bits (93), Expect = 0.014
Identities = 36/112 (32%), Positives = 45/112 (40%), Gaps = 42/112 (37%)
Query: 413 DMETNECLEN---NGGCWKEKSSNITACRDTFRGRVCVCPVVNNIKFVGDGY--THCEAS 467
++E +EC N NGG +C+D G C+CP GY HCE S
Sbjct: 322 ELELSECDSNPCRNGG----------SCKDQEDGYHCLCP---------PGYYGLHCEHS 362
Query: 468 GTLSCE----FNNGGCWKASHGGRLYSACHDDYRKGCECPSGFRGDGVRSCE 515
TLSC FN G C + + G CECP F G +CE
Sbjct: 363 -TLSCADSPCFNGGSCRERNQGANY----------ACECPPNFTGS---NCE 400
>SBN2_MOUSE (Q8R4U0) Stabilin 2 precursor [Contains: Short form
stabilin 2]
Length = 2559
Score = 40.0 bits (92), Expect = 0.018
Identities = 38/126 (30%), Positives = 51/126 (40%), Gaps = 29/126 (23%)
Query: 388 SRPAVLKAMCAGFQETTEPSICLTPDMETNECLENNGGCWKEKSSNITACRDTFRGRVCV 447
SR V KA G + +CL E N CLEN+GGC + T VC
Sbjct: 1502 SRVCVCKAGYTG-----DGIVCL----EINPCLENHGGCDRHAECTQTGPNQA----VCN 1548
Query: 448 CPVVNNIKFVGDGYTHCEASGTLSCEFNNGGCWKASHGGRLYSACH--DDYRKGCECPSG 505
C K+ GDG C C NNGGC ++ C+ + ++ C C
Sbjct: 1549 CLP----KYTGDGKV-CTLINV--CLTNNGGC-------SPFAFCNHTEQDQRTCTCKPD 1594
Query: 506 FRGDGV 511
+ GDG+
Sbjct: 1595 YTGDGI 1600
Score = 37.0 bits (84), Expect = 0.15
Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 14/71 (19%)
Query: 446 CVCPVVNNIKFVGDGYTHCEASGTLSCEFNNGGCWKASHGGRLYSACHDDYRKGCECPSG 505
CVC N+ + GDG T C+ NNGGC K + + C C G
Sbjct: 2075 CVC----NLNYEGDGITCTVVD---FCKQNNGGCAKVA------KCSQKGTQVSCSCQKG 2121
Query: 506 FRGDGVRSCED 516
++GDG SC +
Sbjct: 2122 YKGDG-HSCTE 2131
Score = 34.3 bits (77), Expect = 0.99
Identities = 38/156 (24%), Positives = 57/156 (36%), Gaps = 37/156 (23%)
Query: 389 RPAVLKAMCAGFQETTEPSICLTPDMETNECLENN---------GGCWKEKSSNITACRD 439
R + A CAGF P P N C N G C E+ N TAC
Sbjct: 1336 RTIITSACCAGF---FGPQCQACPGKGQNVCSGNGFCLDGVNGTGTCECEQGFNGTACET 1392
Query: 440 TFRGRVCV-----CPVVN---NIKFVGDGYTHCEAS-------GTLSCEFNNGGCWKASH 484
G+ + C V+ N GDG C+ ++ + NG C +++
Sbjct: 1393 CTEGKYGIHCDQACSCVHGRCNQGPSGDGSCDCDVGWRGVKCDSEITTDNCNGTCHTSAN 1452
Query: 485 GGRLYSACHDDYRKGCECPSGFRGDG-----VRSCE 515
D + C+C +GF+G+G + +CE
Sbjct: 1453 -----CLLDPDGKASCKCAAGFQGNGTVCTAINACE 1483
Score = 33.9 bits (76), Expect = 1.3
Identities = 31/103 (30%), Positives = 43/103 (41%), Gaps = 29/103 (28%)
Query: 419 CLENNGGCWKEKSSNITACRDTFRGRVCVCPVVNNIKFVGDGYTHCE----ASGTLSCEF 474
C +NNGGC K + C C C + GDG++ E A+G
Sbjct: 2094 CKQNNGGCAK-----VAKCSQKGTQVSCSC----QKGYKGDGHSCTEIDPCANGV----- 2139
Query: 475 NNGGCWKASHGGRLYSACH--DDYRKGCECPSGFRGDGVRSCE 515
NGGC + ++ C ++ CEC S + GDG R CE
Sbjct: 2140 -NGGCHE-------HATCRMTGPGKQKCECKSHYVGDG-RDCE 2173
Score = 31.6 bits (70), Expect = 6.4
Identities = 43/172 (25%), Positives = 59/172 (34%), Gaps = 38/172 (22%)
Query: 374 PTLVINNRQYRGKLSRPAVLKAMCAGFQETTE--PSIC---LTPDMET------NECLEN 422
PT + N+ + G SR LK CA + + T P C PD N C
Sbjct: 701 PTAIFTNKCFYG--SRAWNLKIGCARYCDVTVEIPRCCKGFFGPDCNPCPGGFMNPC-SG 757
Query: 423 NGGCWKEKSSNITA-CRDTFRGRVC---------------VCPVVNNI---KFVGDGY-- 461
NG C N T C D F+G C C V+ I + DG
Sbjct: 758 NGQCIDGLGGNGTCICEDGFQGSRCQFCSKPNRYGPQCNRTCQCVHGICDNRLDSDGSCL 817
Query: 462 --THCEASGTLSCEFNNGGCWKASHGGRLYSAC-HDDYRKGCECPSGFRGDG 510
T E + C+ C +++ C + + C C G+ GDG
Sbjct: 818 PGTCREGTAGRFCDKQTSACGPYMQFCHIHATCEYSNETASCVCNDGYEGDG 869
Score = 31.2 bits (69), Expect = 8.4
Identities = 39/169 (23%), Positives = 63/169 (37%), Gaps = 46/169 (27%)
Query: 414 METNECL-ENNGGCWKEKS-------SNITACRDTFRGRVCVC-PVVNNIKFVGDGYTHC 464
+E N CL ++GGC + N C+ FRG C P+++ ++ + C
Sbjct: 917 VEINSCLLPSSGGCHDNATCLYVGPGQNECECKKGFRGNGIDCEPIISCLEQI----EKC 972
Query: 465 EASGTLSCEFNNGGCWKASHGGRLYSACHDDYRKGCECPSGFRGDGVRSCEDCFNIFRIL 524
T C++ G W C C G+ G+GV C+ +L
Sbjct: 973 HPLAT--CQYTLSGVWS------------------CVCQEGYEGNGVL----CYG--NVL 1006
Query: 525 TMLQILMNA-------KKSRLASVHNANAKIPLGVMSASAIAVCSTHEK 566
L L A + L S+ +A + + + V S AI +EK
Sbjct: 1007 MELSFLSEAAVFYQWINNASLQSMLSATSNLTVLVPSLQAIKDMDQNEK 1055
>RN13_CHICK (Q90972) RING finger protein 13 (C-RZF)
Length = 381
Score = 40.0 bits (92), Expect = 0.018
Identities = 28/92 (30%), Positives = 49/92 (52%), Gaps = 8/92 (8%)
Query: 94 VLVDRGDCYFTLKAWNAQNGGAAAILVADDREETLITMDTPEEGNVVND-DYIEKINIPS 152
VL+ R +C F +K NAQ G A +V + + LI+M + ND + ++KI+IPS
Sbjct: 95 VLIRRLECNFDIKVLNAQRAGYKAAIVHNVDSDDLISMGS-------NDIEILKKIDIPS 147
Query: 153 ALISKSLGDRIKKALSDGEMVHINLDWREALP 184
I ++ + +K+ + + H+ L +LP
Sbjct: 148 VFIGEASANSLKEEFTYEKGGHVVLIPEFSLP 179
>SBN2_RAT (Q8CFM6) Stabilin 2 precursor (Hyaluronan receptor for
endocytosis) [Contains: 175 kDa stabilin 2 (175 kDa
hyaluronan receptor for endocytosis)] (Fragment)
Length = 1431
Score = 39.7 bits (91), Expect = 0.024
Identities = 38/129 (29%), Positives = 54/129 (41%), Gaps = 27/129 (20%)
Query: 386 KLSRPAVLKAMC-AGFQETTEPSICLTPDMETNECLENNGGCWKEKSSNITACRDTFRGR 444
K + P +C AG+ T + +CL E N CLEN+GGC + T
Sbjct: 353 KRTTPGNRVCVCKAGY--TGDGIVCL----EINPCLENHGGCDRNAECTQTGPNQA---- 402
Query: 445 VCVCPVVNNIKFVGDGYTHCEASGTLSCEFNNGGCWKASHGGRLYSACH--DDYRKGCEC 502
VC C K+ GDG C C NNGGC ++ C+ + ++ C C
Sbjct: 403 VCNCLP----KYTGDGKV-CSLINV--CLTNNGGC-------SPFAFCNYTEQDQRICTC 448
Query: 503 PSGFRGDGV 511
+ GDG+
Sbjct: 449 KPDYTGDGI 457
Score = 36.6 bits (83), Expect = 0.20
Identities = 22/70 (31%), Positives = 29/70 (41%), Gaps = 13/70 (18%)
Query: 446 CVCPVVNNIKFVGDGYTHCEASGTLSCEFNNGGCWKASHGGRLYSACHDDYRKGCECPSG 505
CVC N+ + GDG T C+ NNGGC K + + C C G
Sbjct: 932 CVC----NLNYEGDGITCTVVD---FCKQNNGGCAKVA------KCSQKGTQVSCSCKKG 978
Query: 506 FRGDGVRSCE 515
++GDG E
Sbjct: 979 YKGDGYSCIE 988
Score = 34.7 bits (78), Expect = 0.76
Identities = 30/99 (30%), Positives = 40/99 (40%), Gaps = 21/99 (21%)
Query: 419 CLENNGGCWKEKSSNITACRDTFRGRVCVCPVVNNIKFVGDGYTHCEASGTLSCEFNNGG 478
C +NNGGC K + C C C + GDGY+ E + NGG
Sbjct: 951 CKQNNGGCAK-----VAKCSQKGTQVSCSCKK----GYKGDGYSCIEIDPC--ADGVNGG 999
Query: 479 CWKASHGGRLYSACH--DDYRKGCECPSGFRGDGVRSCE 515
C + ++ C + CEC S + GDGV CE
Sbjct: 1000 CHE-------HATCRMTGPGKHKCECKSHYVGDGV-DCE 1030
Score = 32.7 bits (73), Expect = 2.9
Identities = 38/156 (24%), Positives = 56/156 (35%), Gaps = 37/156 (23%)
Query: 389 RPAVLKAMCAGFQETTEPSICLTPDMETNECLENN---------GGCWKEKSSNITACRD 439
R + +A CAGF P P N C N G C N TAC
Sbjct: 193 RTIITRACCAGF---FGPQCQACPGRGQNVCSGNGFCLDGVNGTGTCQCGLGFNGTACET 249
Query: 440 TFRGRVCV-----CPVVNNIKF---VGDGYTHCEASGT-LSCEFN------NGGCWKASH 484
G+ + C V+ +GDG C+ + C+ NG C +++
Sbjct: 250 CTEGKYGIHCDQACSCVHGRCSQGPLGDGSCDCDVGWRGVKCDMEITTDNCNGTCHTSAN 309
Query: 485 GGRLYSACHDDYRKGCECPSGFRGDG-----VRSCE 515
D + C+C +GFRG+G + +CE
Sbjct: 310 -----CLLDPDGKASCKCAAGFRGNGTVCTAINACE 340
Score = 31.2 bits (69), Expect = 8.4
Identities = 20/75 (26%), Positives = 28/75 (36%), Gaps = 23/75 (30%)
Query: 437 CRDTFRGRVCVCPVVNNIKFVGDGYTHCEASGTLSCEFNNGGCWKASHGGRLYSACHDDY 496
C FRG VC +N +CE +NGGC + R
Sbjct: 322 CAAGFRGNGTVCTAIN------------------ACETSNGGCSTKADCKRTTPG----- 358
Query: 497 RKGCECPSGFRGDGV 511
+ C C +G+ GDG+
Sbjct: 359 NRVCVCKAGYTGDGI 373
>C122_HUMAN (Q9BZQ6) Putative alpha-mannosidase C1orf22 (EC 3.2.1.-)
Length = 889
Score = 39.7 bits (91), Expect = 0.024
Identities = 34/118 (28%), Positives = 51/118 (42%), Gaps = 5/118 (4%)
Query: 95 LVDRGDCYFTLKAWNAQNGGAAAILVADDREETLITMDTPEEGNVVNDDY-IEKINIPSA 153
L+ RG C F KA N QN GA +V DD E + + DT + D + I IP
Sbjct: 665 LIQRGQCMFAEKARNIQNAGAIGGIVIDDNEGS--SSDTAPLFQMAGDGKDTDDIKIPML 722
Query: 154 LISKSLGDRIKKALSDGEMVHINLDWREALPHPDDRVEYELWTNSNDECGPKCDNQIN 211
+ G I A+ + E V + L + D +E E +S ++ + QI+
Sbjct: 723 FLFSKEGSIILDAIREYEEVEVLLS--DKAKDRDPEMENEEQPSSENDSQNQSGEQIS 778
>SBN1_MOUSE (Q8R4Y4) Stabilin 1 precursor (FEEL-1 protein)
Length = 2571
Score = 39.3 bits (90), Expect = 0.031
Identities = 29/104 (27%), Positives = 43/104 (40%), Gaps = 22/104 (21%)
Query: 415 ETNECLENNGGCWKEKSSNITACRDTFRG-RVCVCPVVNNIKFVGDGYTHCEASGTLSCE 473
E + C +GGC S C G R C C + GDG E + SC
Sbjct: 1456 EVDPCASGHGGC-----SPYANCTKVAPGQRTCTC----QDGYTGDGELCQEIN---SCL 1503
Query: 474 FNNGGCWKASHGGRLYSAC--HDDYRKGCECPSGFRGDGVRSCE 515
+NGGC +++ C + C C G+ GDG+++C+
Sbjct: 1504 VHNGGC-------HVHAECIPTGPQQVSCSCREGYSGDGIQTCK 1540
Score = 35.4 bits (80), Expect = 0.44
Identities = 35/105 (33%), Positives = 41/105 (38%), Gaps = 23/105 (21%)
Query: 408 ICLTPDMETNEC-LENNGGCWKEKSSNITACRDTFRGRV-CVCPVVNNIKFVGDGYTHCE 465
IC+ D EC L+ GGC + C G+ C C + F G+GY E
Sbjct: 902 ICVAID----ECGLDTRGGCHAD-----ALCSYVGPGQSRCTC----KLGFAGNGY---E 945
Query: 466 ASGTLSCEFNNGGCWKASHGGRLYSACHDDYRKGCECPSGFRGDG 510
S C NGGC HG A R C CP F GDG
Sbjct: 946 CSPIDPCRVGNGGC----HGLATCKAVGGGQRV-CTCPPHFGGDG 985
Score = 32.0 bits (71), Expect = 4.9
Identities = 28/109 (25%), Positives = 49/109 (44%), Gaps = 20/109 (18%)
Query: 408 ICLTPDMETNECLENNGGCWKEKSSNITACRDTFRGRVCVCPVVNNIKFVGDGYTHCEAS 467
+C D+ C + +GGC K + + G V C + + + GDG++ C A
Sbjct: 2088 VCTVADL----CQKGHGGCSKHANCSQV-------GTVVTCTCLPD--YEGDGWS-CRAR 2133
Query: 468 GTLSCEFNNGGCWKASHGGRLYSACHDDYRKGCECPSGFRGDGVRSCED 516
+ + GGC + H L + + + CEC G+ GDG++ E+
Sbjct: 2134 DPC-LDGHRGGC--SEHADCLNTGPNT---RRCECHVGYVGDGLQCLEE 2176
>LDLR_CRIGR (P35950) Low-density lipoprotein receptor precursor (LDL
receptor)
Length = 854
Score = 38.9 bits (89), Expect = 0.040
Identities = 34/117 (29%), Positives = 49/117 (41%), Gaps = 22/117 (18%)
Query: 393 LKAMCAGFQETTEPSICLTPDMETNECLENNGGCWKEKSSNITACRDTFRGRVCVCPVVN 452
L +C ++ + S D TNECL+NNGGC S++ C+D G C+CP N
Sbjct: 293 LDKVCDSMRDCRDWSDEPIKDCRTNECLDNNGGC-----SHV--CKDLKIGYECLCP--N 343
Query: 453 NIKFVGDGYTHCEASGTLSCEFNNGGCWKASHGGRLYSACHDDYRKGCECPSGFRGD 509
+ V CE + C + +L Y+ CEC +GF D
Sbjct: 344 GFQLVDQ--HRCE---------DIDECQEPDTCDQLCVNLEGSYK--CECRAGFHMD 387
>YLK2_CAEEL (P41950) Hypothetical protein D1044.2 precursor
Length = 1090
Score = 37.7 bits (86), Expect = 0.090
Identities = 44/156 (28%), Positives = 62/156 (39%), Gaps = 25/156 (16%)
Query: 448 CPVVNNIKFVGDGYTHCEASGTLSCEFNNGGCWKASHGGRLYSACHDDYRKGCECPSGFR 507
C +N K GDGY +CE C+ N+ C K + + R C C GF
Sbjct: 393 CQCLNGYK--GDGYNNCEDVD--ECKTNSTICHKNA------ICTNTPGRYFCMCKEGFS 442
Query: 508 GDGVRSCEDCFNIFRILTMLQILMNAKKSRLASVHNANAKIPLGVMSASAIAVCSTHEKM 567
GDG C F +F+ T Q L K S++ N K PL + T EK+
Sbjct: 443 GDGQNDCSQSF-LFQYDTHHQ-LPRKKNSKM----EWNLKKPLKIFG-------ETTEKL 489
Query: 568 TRVLSGGYAFYKYRIQ--RYMDTEIRAIMAQYMPLD 601
T +G A + R D ++ I + P+D
Sbjct: 490 TVTSTGLIAINEVNRDNGRLEDMQLVGIAPFFGPID 525
Score = 32.0 bits (71), Expect = 4.9
Identities = 11/28 (39%), Positives = 19/28 (67%), Gaps = 1/28 (3%)
Query: 489 YSACHDDYRKGCECPSGFRGDGVRSCED 516
Y C + ++ C+C +G++GDG +CED
Sbjct: 383 YDRCGEPIQR-CQCLNGYKGDGYNNCED 409
>LDLR_RAT (P35952) Low-density lipoprotein receptor precursor (LDL
receptor)
Length = 879
Score = 37.4 bits (85), Expect = 0.12
Identities = 31/97 (31%), Positives = 46/97 (46%), Gaps = 22/97 (22%)
Query: 413 DMETNECLENNGGCWKEKSSNITACRDTFRGRVCVCPVVNNIKFVGDGYTHCEASGTLSC 472
+ +TNECL+NNGGC S+I C+D G C+CP + + V DG+ CE
Sbjct: 313 ECKTNECLDNNGGC-----SHI--CKDLKIGYECLCP--SGFRLV-DGH-QCE------- 354
Query: 473 EFNNGGCWKASHGGRLYSACHDDYRKGCECPSGFRGD 509
+ C + +L ++ CEC +GF D
Sbjct: 355 --DIDECQEPDTCSQLCVNLEGSFK--CECRAGFHMD 387
>LDLR_MOUSE (P35951) Low-density lipoprotein receptor precursor (LDL
receptor)
Length = 864
Score = 37.4 bits (85), Expect = 0.12
Identities = 18/37 (48%), Positives = 24/37 (64%), Gaps = 7/37 (18%)
Query: 413 DMETNECLENNGGCWKEKSSNITACRDTFRGRVCVCP 449
+ +TNECL+NNGGC S+I C+D G C+CP
Sbjct: 313 ECKTNECLDNNGGC-----SHI--CKDLKIGSECLCP 342
Score = 32.0 bits (71), Expect = 4.9
Identities = 25/69 (36%), Positives = 29/69 (41%), Gaps = 10/69 (14%)
Query: 469 TLSCEFNNGGCWKASHGGRLYSACHD-DYRKGCECPSGFRGDGVRSCEDCFNIFRILTML 527
T C NNGGC SH C D C CPSGFR + CED T
Sbjct: 316 TNECLDNNGGC---SH------ICKDLKIGSECLCPSGFRLVDLHRCEDIDECQEPDTCS 366
Query: 528 QILMNAKKS 536
Q+ +N + S
Sbjct: 367 QLCVNLEGS 375
>EFL3_RAT (O88281) Multiple EGF-like-domain protein 3 precursor
(Multiple epidermal growth factor-like domains 6)
Length = 1574
Score = 37.4 bits (85), Expect = 0.12
Identities = 31/111 (27%), Positives = 42/111 (36%), Gaps = 23/111 (20%)
Query: 397 CAGFQETTEPSICLTPDMETNECLENNGGCWKEKSSNITACRDTFRGRVCVCPVVNNIKF 456
C G+ + CL+ + +EC NGGC C +T G C CP +
Sbjct: 108 CPGWSQKPGQEGCLS---DVDECASANGGC-------EGPCCNTVGGFYCRCP--PGYQL 155
Query: 457 VGDGYTHCEASGTLSCEFNNGGCWKASHGGRLYSACHDDYRKGCECPSGFR 507
GDG T + C +NGGC + + CEC GFR
Sbjct: 156 QGDGKTCQDVD---ECRAHNGGC--------QHRCVNTPGSYLCECKPGFR 195
Score = 32.7 bits (73), Expect = 2.9
Identities = 27/87 (31%), Positives = 33/87 (37%), Gaps = 12/87 (13%)
Query: 437 CRDTFRGRVCVCPVVNNIKFVGDGYTHCEASGTLSCEFNNGGCWKASHGGRLYSACHDDY 496
C +T CVC + G E SCE NGGC SHG H
Sbjct: 303 CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEAGNGGC---SHG-----CSHTST 354
Query: 497 RKGCECPSGFRGD-GVRSC---EDCFN 519
C CP G+ D ++C +DC N
Sbjct: 355 GPLCTCPRGYELDEDQKTCIDIDDCAN 381
>DLL3_HUMAN (Q9NYJ7) Delta-like protein 3 precursor (Drosophila
Delta homolog 3)
Length = 618
Score = 37.4 bits (85), Expect = 0.12
Identities = 35/113 (30%), Positives = 44/113 (37%), Gaps = 20/113 (17%)
Query: 407 SICLTP---DMETNECL-ENNGGCWKEKSSNITACRDTFRGRVCVCPVVNNIKFVGDGYT 462
S CL+P T CL G C +N +C +T R C CP F G
Sbjct: 255 SSCLSPRGPSSATTGCLVPGPGPCDGNPCANGGSCSETPRSFECTCPR----GFYG---L 307
Query: 463 HCEASGTLSCEFNNGGCWKASHGGRLYSACHDDYRKGCECPSGFRGDGVRSCE 515
CE SG + G C+ +GG D C CP GF+G +CE
Sbjct: 308 RCEVSGVTCAD---GPCF---NGGLCVGGADPDSAYICHCPPGFQGS---NCE 351
>TSP1_MOUSE (P35441) Thrombospondin 1 precursor
Length = 1170
Score = 37.0 bits (84), Expect = 0.15
Identities = 42/169 (24%), Positives = 62/169 (35%), Gaps = 19/169 (11%)
Query: 363 GKESRGDVTILPTLVINNRQYRGKLSRPAVLKAMCAGFQETTEPSICLTPDMETN----- 417
GK+ GDVT + G LS P A C + + + P N
Sbjct: 528 GKDCVGDVTENQVCNKQDCPIDGCLSNPCFAGAKCTSYPDGSWKCGACPPGYSGNGIQCK 587
Query: 418 ---ECLENNGGCWKEKSSNITACRDTFRGRVCV-CPV-VNNIKFVGDGYTHCEASGTLSC 472
EC E C+ + C++T G C+ CP + G G H A+ + C
Sbjct: 588 DVDECKEVPDACFNHNGEH--RCKNTDPGYNCLPCPPRFTGSQPFGRGVEHAMANKQV-C 644
Query: 473 EFNNGGCWKASHGGRLYSAC-----HDDYRKGCECPSGFRGDGVRSCED 516
+ N C +H + C + D CEC G+ G+G+ ED
Sbjct: 645 KPRNP-CTDGTHDCNKNAKCNYLGHYSDPMYRCECKPGYAGNGIICGED 692
>SEN2_HUMAN (Q8NCE0) tRNA-splicing endonuclease subunit SEN2 (EC
3.1.27.9) (tRNA-intron endonuclease SEN2) (HsSen2
protein)
Length = 465
Score = 37.0 bits (84), Expect = 0.15
Identities = 37/152 (24%), Positives = 69/152 (45%), Gaps = 15/152 (9%)
Query: 262 APDPEQDFNKGYDGKDVVVQNLRQACFFKVANESGRPWQWWDYVTDFSIRCPMKEKKYTE 321
A D EQ + KGY GK ++ R F +++ +W D T+ I K +++
Sbjct: 54 AEDIEQLYGKGYFGKGILS---RSRPSFTISDPK-LVAKWKDMKTNMPI-ITSKRYQHSV 108
Query: 322 ECSDEVIKSLGVDLKKIKDCVGDPLADVENPVLKAEQEAQIGKESRGDVTILPTLVINNR 381
E + E+++ G D ++ + D +E+P +K +EAQ+ + L + +++N
Sbjct: 109 EWAAELMRRQGQDESTVRRILKDYTKPLEHPPVKRNEEAQVHDK-------LNSGMVSNM 161
Query: 382 QYRGKLSRPAVL---KAMCAGFQETTEPSICL 410
+ RP+V+ G + EP CL
Sbjct: 162 EGTAGGERPSVVNGDSGKSGGVGDPREPLGCL 193
>LI12_CAEEL (P14585) Lin-12 protein precursor
Length = 1429
Score = 36.6 bits (83), Expect = 0.20
Identities = 31/112 (27%), Positives = 42/112 (36%), Gaps = 24/112 (21%)
Query: 413 DMETNECLENNGGCWKEKSSNITACRDTFRGRVCVCPVVNNIKFVGDGYTHCEASG-TLS 471
+++ NEC EN C N + C +T +CVCP G C G T +
Sbjct: 150 ELDVNECEENKNAC-----GNRSTCMNTLGTYICVCP-------QGFLPPDCLKPGNTST 197
Query: 472 CEFNNGGCW---KASHGGRLYSACH-----DDYRKGCECPSGFRGDGVRSCE 515
EF C+ A H C D C+CP G+ G +CE
Sbjct: 198 VEFKQPVCFLEISADHPDGRSMYCQNGGFCDKASSKCQCPPGYHGS---TCE 246
>PRKD_MOUSE (P97313) DNA-dependent protein kinase catalytic subunit
(EC 2.7.1.37) (DNA-PKcs) (P460)
Length = 4128
Score = 36.2 bits (82), Expect = 0.26
Identities = 38/143 (26%), Positives = 64/143 (44%), Gaps = 24/143 (16%)
Query: 123 DREETLITMDTPEEGNVVNDDYIEKINIPSALISKSLG--------------DRIKKALS 168
D+EE + T EE + D+Y + I P + S+S +RIK L
Sbjct: 3507 DKEEAIAVQHTVEE---IADNYPQAIIYPFIISSESYSFKNTSSGHNNKAFVERIKSKLD 3563
Query: 169 DGEMVHINLDWREALPHPDDRVEYELW-TNSNDECGPKCDNQINFVKSFK---GAAQLLE 224
GE++H ++ + L +PD + ++ W +++ DE G N+ N K ++ A L
Sbjct: 3564 HGEVIHSFINALDQLSNPD--LLFKDWVSDTKDELGKNPVNKKNIEKLYERMYAALGDLR 3621
Query: 225 KKGFTQFTPHYITWYCPKEFLLS 247
G F +I + KEF+ S
Sbjct: 3622 APGLGPFRRRFIQAF-GKEFVKS 3643
>NTC4_MOUSE (P31695) Neurogenic locus notch homolog protein 4
precursor (Notch 4) [Contains: Transforming protein
Int-3]
Length = 1964
Score = 36.2 bits (82), Expect = 0.26
Identities = 31/112 (27%), Positives = 43/112 (37%), Gaps = 15/112 (13%)
Query: 408 ICLTPDMETN-ECLENNGGCWKEKSSNITACRDTFRGRVCVCPVVNNIKFVGDGYTHCEA 466
+CL P T +C N C + + N C D C+CP + CEA
Sbjct: 258 LCLCPPGFTGLDCEMNPDDCVRHQCQNGATCLDGLDTYTCLCPKTWKGWDCSEDIDECEA 317
Query: 467 SGTLSCEFNNGGCWKASHGGRLYSACHDDYRKGCECPSGFRGDGV-RSCEDC 517
G C NGG + + G + H C C SG+ G G + +DC
Sbjct: 318 RGPPRC--RNGGTCQNTAG-----SFH------CVCVSGWGGAGCEENLDDC 356
Score = 31.6 bits (70), Expect = 6.4
Identities = 30/112 (26%), Positives = 42/112 (36%), Gaps = 26/112 (23%)
Query: 411 TPDMETNECLENNGGCWKEKSSNITACRDTFRGRVCVCPVVNNIKFVGDGYTHCEASGTL 470
T + + NEC G C + T+C +T C+CPV
Sbjct: 187 TCERDINECFLEPGPCPQG-----TSCHNTLGSYQCLCPV---------------GQEGP 226
Query: 471 SCEFNNGGCWKAS--HGG--RLYSACHDDYRKGCECPSGFRG-DGVRSCEDC 517
C+ G C S +GG +L H + C CP GF G D + +DC
Sbjct: 227 QCKLRKGACPPGSCLNGGTCQLVPEGHSTFHL-CLCPPGFTGLDCEMNPDDC 277
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.321 0.138 0.437
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,354,786
Number of Sequences: 164201
Number of extensions: 3614080
Number of successful extensions: 8065
Number of sequences better than 10.0: 90
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 84
Number of HSP's that attempted gapping in prelim test: 7732
Number of HSP's gapped (non-prelim): 382
length of query: 617
length of database: 59,974,054
effective HSP length: 116
effective length of query: 501
effective length of database: 40,926,738
effective search space: 20504295738
effective search space used: 20504295738
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)
Medicago: description of AC146784.6