BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC146757.7 - phase: 0
(367 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
PDK_DROME (P91622) [Pyruvate dehydrogenase [lipoamide]] kinase, ... 241 2e-63
PDK2_RAT (Q64536) [Pyruvate dehydrogenase [lipoamide]] kinase is... 237 3e-62
PDK2_MOUSE (Q9JK42) [Pyruvate dehydrogenase [lipoamide]] kinase ... 237 4e-62
PDK2_HUMAN (Q15119) [Pyruvate dehydrogenase [lipoamide]] kinase ... 236 5e-62
PDK1_RAT (Q63065) [Pyruvate dehydrogenase [lipoamide]] kinase is... 235 2e-61
PDK1_HUMAN (Q15118) [Pyruvate dehydrogenase [lipoamide]] kinase ... 230 5e-60
PDK4_HUMAN (Q16654) [Pyruvate dehydrogenase [lipoamide]] kinase ... 228 2e-59
PDK3_HUMAN (Q15120) [Pyruvate dehydrogenase [lipoamide]] kinase ... 228 2e-59
PDK4_MOUSE (O70571) [Pyruvate dehydrogenase [lipoamide]] kinase ... 227 3e-59
PDK4_SPETR (O88345) [Pyruvate dehydrogenase [lipoamide]] kinase ... 227 4e-59
PDK_ASCSU (O02623) [Pyruvate dehydrogenase [lipoamide]] kinase, ... 224 3e-58
PDK4_RAT (O54937) [Pyruvate dehydrogenase [lipoamide]] kinase is... 224 3e-58
BCKD_MOUSE (O55028) [3-methyl-2-oxobutanoate dehydrogenase [lipo... 216 7e-56
BCKD_RAT (Q00972) [3-methyl-2-oxobutanoate dehydrogenase [lipoam... 215 1e-55
BCKD_HUMAN (O14874) [3-methyl-2-oxobutanoate dehydrogenase [lipo... 214 2e-55
PDK_CAEEL (Q02332) Probable [pyruvate dehydrogenase [lipoamide]]... 209 1e-53
YIE2_YEAST (P40530) Hypothetical 45.4 kDa protein in CBR5-NOT3 i... 92 2e-18
YGF9_YEAST (P53170) Hypothetical 51.9 kDa protein in PYC1-UBC2 i... 90 1e-17
VIRA_AGRTU (P07168) Wide host range virA protein (EC 2.7.3.-) (W... 46 2e-04
VIRA_AGRT9 (P10799) Wide host range virA protein (EC 2.7.3.-) (W... 45 4e-04
>PDK_DROME (P91622) [Pyruvate dehydrogenase [lipoamide]] kinase,
mitochondrial precursor (EC 2.7.1.99) (Pyruvate
dehydrogenase kinase) (DmPDK)
Length = 413
Score = 241 bits (616), Expect = 2e-63
Identities = 142/352 (40%), Positives = 206/352 (58%), Gaps = 20/352 (5%)
Query: 26 VSLRYMMEFGSQPTDKNLLISAQFLQKELAIRIARRAIELESLPYGLSKKPAILKVRDWY 85
+S++ M+FG +K I FL+KEL +R+A E+ LP L ++ +V WY
Sbjct: 33 LSIKQFMDFGQNACEKKSYI---FLRKELPVRLANIMKEIALLPDNLLHTRSVSEVSSWY 89
Query: 86 VDSFRDIRSCPEVKDMKDE-REFTDVIKAIKVRHNNVVPTMALGVQQLKKELKTKIDSED 144
V SF D+ + + D ++F + I+ RHN+VV TMA GV ++K+ ++D+
Sbjct: 90 VKSFEDVLVYEKAEPTHDNLQKFVADLDLIRNRHNDVVQTMAQGVIEMKENEGGQVDAPT 149
Query: 145 LVEIHEFLDRFYLSRIGVRMLIGQHVELH--NPNPPPHVVGYIHTKMSPVSVARNASEDA 202
I FLDR Y+SRI +RMLI QH L NP+ +G + V R+A E+A
Sbjct: 150 ESSIQYFLDRLYMSRISIRMLINQHTLLFGGNPHAGGRHIGCLDPACDLSDVVRDAYENA 209
Query: 203 RSICMREYGSAPEINIY---GDPDFTFP----YVPAHLHLMVFELVKNSLRAVQERY-MD 254
R +C + Y ++P + I +P P YVP+HL+ M+FEL KNS+RAV E + D
Sbjct: 210 RFLCDQYYLTSPALEIQQHSSEPGDNLPIRTVYVPSHLYYMLFELFKNSMRAVVEHHGHD 269
Query: 255 SDKVSPPIRIIVADGLEDVTIKISDEGGGIPRSGLPKIFTYLYSTARNPLDEHADLGVAD 314
++ PP+++ + G ED+ +KISD+GGGIPRS ++F Y+YSTA P +DL
Sbjct: 270 NNDTLPPLKVAICKGKEDICVKISDQGGGIPRSQTDQLFKYMYSTAPQP--SKSDL---- 323
Query: 315 SVTTMAGYGYGLPISRLYARYFGGDLQIISMEGYGTDAYLHLSRLGDSQEPL 366
+AGYGYGLPISRLYARYF GD+ ++S EG+GTDA ++L L D L
Sbjct: 324 HTVPLAGYGYGLPISRLYARYFHGDIVLLSCEGFGTDAIIYLKALSDEANEL 375
>PDK2_RAT (Q64536) [Pyruvate dehydrogenase [lipoamide]] kinase
isozyme 2, mitochondrial precursor (EC 2.7.1.99)
(Pyruvate dehydrogenase kinase isoform 2) (PDK P45)
Length = 407
Score = 237 bits (605), Expect = 3e-62
Identities = 150/356 (42%), Positives = 211/356 (59%), Gaps = 28/356 (7%)
Query: 26 VSLRYMMEFGSQPTDKNLLISAQFLQKELAIRIARRAIELESLPYGLSKKPAILKVRDWY 85
+S++ ++FGS + S FL++EL +R+A E+ LP + P++ V+ WY
Sbjct: 31 LSMKQFLDFGSSNACEKT--SFTFLRQELPVRLANIMKEINLLPDRVLSTPSVQLVQSWY 88
Query: 86 VDSFRDIRSCPEVKDMKDER---EFTDVIKAIKVRHNNVVPTMALGVQQLKKELKTKIDS 142
V S DI + KD +D R +FTD + I+ RHN+VVPTMA GV + K D
Sbjct: 89 VQSLLDIMEFLD-KDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEYKDTYGD--DP 145
Query: 143 EDLVEIHEFLDRFYLSRIGVRMLIGQHVELH----NPNPPPHVVGYIHTKMSPVSVARNA 198
I FLDRFYLSRI +RMLI QH + NP P H+ G I S V ++A
Sbjct: 146 VSNQNIQYFLDRFYLSRISIRMLINQHTLIFDGSTNPAHPKHI-GSIDPNCSVSDVVKDA 204
Query: 199 SEDARSICMREYGSAPEINIY--GDPDFTFP----YVPAHLHLMVFELVKNSLRAVQERY 252
+ A+ +C + Y ++P++ I + T P YVP+HL+ M+FEL KN++RA E +
Sbjct: 205 YDMAKLLCDKYYMASPDLEIQEVNATNATQPIHMVYVPSHLYHMLFELFKNAMRATVESH 264
Query: 253 MDSDKVSPPIRIIVADGLEDVTIKISDEGGGIPRSGLPKIFTYLYSTARNPLDEHADLGV 312
+S PPI+I+VA G ED++IK+SD GGG+P + ++F+Y+YSTA P
Sbjct: 265 -ESSLTLPPIKIMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTAPTPQP------- 316
Query: 313 ADSVTTMAGYGYGLPISRLYARYFGGDLQIISMEGYGTDAYLHLSRLG-DSQEPLP 367
T +AG+GYGLPISRLYA+YF GDLQ+ SMEG+GTDA ++L L DS E LP
Sbjct: 317 GTGGTPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVERLP 372
>PDK2_MOUSE (Q9JK42) [Pyruvate dehydrogenase [lipoamide]] kinase
isozyme 2, mitochondrial precursor (EC 2.7.1.99)
(Pyruvate dehydrogenase kinase isoform 2)
Length = 407
Score = 237 bits (604), Expect = 4e-62
Identities = 148/356 (41%), Positives = 209/356 (58%), Gaps = 28/356 (7%)
Query: 26 VSLRYMMEFGSQPTDKNLLISAQFLQKELAIRIARRAIELESLPYGLSKKPAILKVRDWY 85
+S++ ++FGS + S FL++EL +R+A E+ LP + P++ V+ WY
Sbjct: 31 LSMKQFLDFGSSNACEKT--SFTFLRQELPVRLANIMKEINLLPDRVLGTPSVQLVQSWY 88
Query: 86 VDSFRDIRSCPEVKDMKDER---EFTDVIKAIKVRHNNVVPTMALGVQQLKKELKTKIDS 142
V S DI + KD +D R +FTD + I+ RHN+VVPTMA GV + K D
Sbjct: 89 VQSLLDIMEFLD-KDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEYKDTYGD--DP 145
Query: 143 EDLVEIHEFLDRFYLSRIGVRMLIGQHVELH----NPNPPPHVVGYIHTKMSPVSVARNA 198
I FLDRFYLSRI +RMLI QH + NP P H+ G I S V ++A
Sbjct: 146 VSNQNIQYFLDRFYLSRISIRMLINQHTLIFDGSTNPAHPKHI-GSIDPNCSVSDVVKDA 204
Query: 199 SEDARSICMREYGSAPEINIY------GDPDFTFPYVPAHLHLMVFELVKNSLRAVQERY 252
+ A+ +C + Y ++P++ I + YVP+HL+ M+FEL KN++RA E +
Sbjct: 205 YDMAKLLCDKYYMASPDLEIQEVNATNANQPIHMVYVPSHLYHMLFELFKNAMRATVESH 264
Query: 253 MDSDKVSPPIRIIVADGLEDVTIKISDEGGGIPRSGLPKIFTYLYSTARNPLDEHADLGV 312
+S PPI+I+VA G ED++IK+SD GGG+P + ++F+Y+YSTA P
Sbjct: 265 -ESSLTLPPIKIMVALGEEDLSIKMSDRGGGVPLRRIERLFSYMYSTAPTPQP------- 316
Query: 313 ADSVTTMAGYGYGLPISRLYARYFGGDLQIISMEGYGTDAYLHLSRLG-DSQEPLP 367
T +AG+GYGLPISRLYA+YF GDLQ+ SMEG+GTDA ++L L DS E LP
Sbjct: 317 GTGGTPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVERLP 372
>PDK2_HUMAN (Q15119) [Pyruvate dehydrogenase [lipoamide]] kinase
isozyme 2, mitochondrial precursor (EC 2.7.1.99)
(Pyruvate dehydrogenase kinase isoform 2)
Length = 407
Score = 236 bits (603), Expect = 5e-62
Identities = 146/356 (41%), Positives = 209/356 (58%), Gaps = 28/356 (7%)
Query: 26 VSLRYMMEFGSQPTDKNLLISAQFLQKELAIRIARRAIELESLPYGLSKKPAILKVRDWY 85
+S++ ++FGS + S FL++EL +R+A E+ LP + P++ V+ WY
Sbjct: 31 LSMKQFLDFGSSNACEKT--SFTFLRQELPVRLANIMKEINLLPDRVLSTPSVQLVQSWY 88
Query: 86 VDSFRDIRSCPEVKDMKDER---EFTDVIKAIKVRHNNVVPTMALGVQQLKKELKTKIDS 142
V S DI + KD +D R +FTD + I+ RHN+VVPTMA GV + K D
Sbjct: 89 VQSLLDIMEFLD-KDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEYKDTYGD--DP 145
Query: 143 EDLVEIHEFLDRFYLSRIGVRMLIGQHVELH----NPNPPPHVVGYIHTKMSPVSVARNA 198
I FLDRFYLSRI +RMLI QH + NP P H+ G I + V ++A
Sbjct: 146 VSNQNIQYFLDRFYLSRISIRMLINQHTLIFDGSTNPAHPKHI-GSIDPNCNVSEVVKDA 204
Query: 199 SEDARSICMREYGSAPEINIY------GDPDFTFPYVPAHLHLMVFELVKNSLRAVQERY 252
+ A+ +C + Y ++P++ I YVP+HL+ M+FEL KN++RA E +
Sbjct: 205 YDMAKLLCDKYYMASPDLEIQEINAANSKQPIHMVYVPSHLYHMLFELFKNAMRATVESH 264
Query: 253 MDSDKVSPPIRIIVADGLEDVTIKISDEGGGIPRSGLPKIFTYLYSTARNPLDEHADLGV 312
+S + PPI+++VA G ED++IK+SD GGG+P + ++F+Y+YSTA P
Sbjct: 265 -ESSLILPPIKVMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTAPTPQP------- 316
Query: 313 ADSVTTMAGYGYGLPISRLYARYFGGDLQIISMEGYGTDAYLHLSRLG-DSQEPLP 367
T +AG+GYGLPISRLYA+YF GDLQ+ SMEG+GTDA ++L L DS E LP
Sbjct: 317 GTGGTPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVERLP 372
>PDK1_RAT (Q63065) [Pyruvate dehydrogenase [lipoamide]] kinase
isozyme 1, mitochondrial precursor (EC 2.7.1.99)
(Pyruvate dehydrogenase kinase isoform 1) (PDK P48)
Length = 434
Score = 235 bits (599), Expect = 2e-61
Identities = 140/356 (39%), Positives = 209/356 (58%), Gaps = 27/356 (7%)
Query: 26 VSLRYMMEFGSQPTDKNLLISAQFLQKELAIRIARRAIELESLPYGLSKKPAILKVRDWY 85
+S++ ++FGS + S FL++EL +R+A E+ LP L + P++ V+ WY
Sbjct: 57 LSMKQFLDFGSVNACEKT--SFMFLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSWY 114
Query: 86 VDSFRDIRSCPE--VKDMKDEREFTDVIKAIKVRHNNVVPTMALGVQQLKKELKTKIDSE 143
+ S +++ + +D K EFTD + I+ RHN+V+PTMA GV + K+ +D
Sbjct: 115 IQSLQELLDFKDKSAEDAKTIYEFTDTVIRIRNRHNDVIPTMAQGVTEYKESFG--VDPV 172
Query: 144 DLVEIHEFLDRFYLSRIGVRMLIGQHVELH----NPNPPPHVVGYIHTKMSPVSVARNAS 199
+ FLDRFY+SRI +RML+ QH L +P+ H+ G I+ V V ++
Sbjct: 173 TSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGSPSHRKHI-GSINPNCDVVEVIKDGY 231
Query: 200 EDARSICMREYGSAPEINIY-------GDPDFTFPYVPAHLHLMVFELVKNSLRAVQERY 252
E+AR +C Y ++PE+ + G P YVP+HL+ MVFEL KN++RA E +
Sbjct: 232 ENARRLCDLYYVNSPELELEELNAKSPGQP-IQVVYVPSHLYHMVFELFKNAMRATMEHH 290
Query: 253 MDSDKVSPPIRIIVADGLEDVTIKISDEGGGIPRSGLPKIFTYLYSTARNPLDEHADLGV 312
D V PPI++ V G ED+T+K+SD GGG+P + ++F Y+YSTA P E
Sbjct: 291 ADKG-VYPPIQVHVTLGEEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVE------ 343
Query: 313 ADSVTTMAGYGYGLPISRLYARYFGGDLQIISMEGYGTDAYLHLSRLG-DSQEPLP 367
+AG+GYGLPISRLYA+YF GDL++ S+EGYGTDA +++ L +S E LP
Sbjct: 344 TSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTESIERLP 399
>PDK1_HUMAN (Q15118) [Pyruvate dehydrogenase [lipoamide]] kinase
isozyme 1, mitochondrial precursor (EC 2.7.1.99)
(Pyruvate dehydrogenase kinase isoform 1)
Length = 436
Score = 230 bits (586), Expect = 5e-60
Identities = 138/358 (38%), Positives = 210/358 (58%), Gaps = 29/358 (8%)
Query: 26 VSLRYMMEFGSQPTDKNLLISAQFLQKELAIRIARRAIELESLPYGLSKKPAILKVRDWY 85
+S++ ++FGS + S FL++EL +R+A E+ LP L + P++ V+ WY
Sbjct: 57 LSMKQFLDFGSVNACEKT--SFMFLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSWY 114
Query: 86 VDSFRDIRSCPE--VKDMKDEREFTDVIKAIKVRHNNVVPTMALGVQQLKKELKTKIDSE 143
+ S +++ + +D K +FTD + I+ RHN+V+PTMA GV + K+ +D
Sbjct: 115 IQSLQELLDFKDKSAEDAKAIYDFTDTVIRIRNRHNDVIPTMAQGVIEYKESFG--VDPV 172
Query: 144 DLVEIHEFLDRFYLSRIGVRMLIGQHVELH------NPNPPPHVVGYIHTKMSPVSVARN 197
+ FLDRFY+SRI +RML+ QH L +P+ H+ G I+ + + V ++
Sbjct: 173 TSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGSPSHRKHI-GSINPNCNVLEVIKD 231
Query: 198 ASEDARSICMREYGSAPEINIY-------GDPDFTFPYVPAHLHLMVFELVKNSLRAVQE 250
E+AR +C Y ++PE+ + G P YVP+HL+ MVFEL KN++RA E
Sbjct: 232 GYENARRLCDLYYINSPELELEELNAKSPGQP-IQVVYVPSHLYHMVFELFKNAMRATME 290
Query: 251 RYMDSDKVSPPIRIIVADGLEDVTIKISDEGGGIPRSGLPKIFTYLYSTARNPLDEHADL 310
+ + V PPI++ V G ED+T+K+SD GGG+P + ++F Y+YSTA P E
Sbjct: 291 HHANRG-VYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVE---- 345
Query: 311 GVADSVTTMAGYGYGLPISRLYARYFGGDLQIISMEGYGTDAYLHLSRLG-DSQEPLP 367
+AG+GYGLPISRLYA+YF GDL++ S+EGYGTDA +++ L DS E LP
Sbjct: 346 --TSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTDSIERLP 401
>PDK4_HUMAN (Q16654) [Pyruvate dehydrogenase [lipoamide]] kinase
isozyme 4, mitochondrial precursor (EC 2.7.1.99)
(Pyruvate dehydrogenase kinase isoform 4)
Length = 411
Score = 228 bits (581), Expect = 2e-59
Identities = 136/366 (37%), Positives = 211/366 (57%), Gaps = 22/366 (6%)
Query: 13 QEVHKWGCLKQTGVSLRYMMEFGSQPTDKNLLISAQFLQKELAIRIARRAIELESLPYGL 72
+EV + + +S++ +++FGS+ + S FL++EL +R+A E++ LP L
Sbjct: 22 REVEHFSRYSPSPLSMKQLLDFGSENACERT--SFAFLRQELPVRLANILKEIDILPTQL 79
Query: 73 SKKPAILKVRDWYVDSFRDIRSCPEVK--DMKDEREFTDVIKAIKVRHNNVVPTMALGVQ 130
++ V+ WY+ S D+ E D K +F D + ++ RH+NVVPTMA G+
Sbjct: 80 VNTSSVQLVKSWYIQSLMDLVEFHEKSPDDQKALSDFVDTLIKVRNRHHNVVPTMAQGII 139
Query: 131 QLKKELKTKIDSEDLVEIHEFLDRFYLSRIGVRMLIGQHVELHNPNPP--PHVVGYIHTK 188
+ K +D + FLDRFY++RI RML+ QH+ + + + P +G I
Sbjct: 140 EYKDACT--VDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPSHIGSIDPN 197
Query: 189 MSPVSVARNASEDARSICMREYGSAPEINI------YGDPDFTFPYVPAHLHLMVFELVK 242
V+V ++A E +R +C + Y S+PE+ + + D YVP+HLH M+FEL K
Sbjct: 198 CDVVAVVQDAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHMLFELFK 257
Query: 243 NSLRAVQERYMDSDKVSPPIRIIVADGLEDVTIKISDEGGGIPRSGLPKIFTYLYSTARN 302
N++RA E + ++P I +IV G ED+TIKISD GGG+P + ++F+Y YSTA
Sbjct: 258 NAMRATVEHQENQPSLTP-IEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTYSTAPT 316
Query: 303 PLDEHADLGVADSVTTMAGYGYGLPISRLYARYFGGDLQIISMEGYGTDAYLHLSRL-GD 361
P+ +++ +AG+GYGLPISRLYA+YF GDL + S+ GYGTDA ++L L +
Sbjct: 317 PVMDNS------RNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLKALSSE 370
Query: 362 SQEPLP 367
S E LP
Sbjct: 371 SIEKLP 376
>PDK3_HUMAN (Q15120) [Pyruvate dehydrogenase [lipoamide]] kinase
isozyme 3, mitochondrial precursor (EC 2.7.1.99)
(Pyruvate dehydrogenase kinase isoform 3)
Length = 406
Score = 228 bits (580), Expect = 2e-59
Identities = 144/370 (38%), Positives = 205/370 (54%), Gaps = 28/370 (7%)
Query: 13 QEVHKWGCLKQTGVSLRYMMEFGSQPTDKNLLISAQFLQKELAIRIARRAIELESLPYGL 72
+++ ++ + +S++ ++FG + S FL+KEL +R+A E+ LP L
Sbjct: 14 KQIERYSRFSPSPLSIKQFLDFGRDNACEKT--SYMFLRKELPVRLANTMREVNLLPDNL 71
Query: 73 SKKPAILKVRDWYVDSFRDI----RSCPEVKDMKDEREFTDVIKAIKVRHNNVVPTMALG 128
+P++ V+ WY+ SF ++ PE + D F V+ ++ RHN+VVPTMA G
Sbjct: 72 LNRPSVGLVQSWYMQSFLELLEYENKSPEDPQVLDN--FLQVLIKVRNRHNDVVPTMAQG 129
Query: 129 VQQLKKELKTKIDSEDLVEIHEFLDRFYLSRIGVRMLIGQHVELH----NPNPPPHVVGY 184
V + K+ K D I FLDRFY +RI RMLI QH L NP P H+ G
Sbjct: 130 VIEYKE--KFGFDPFISTNIQYFLDRFYTNRISFRMLINQHTLLFGGDTNPVHPKHI-GS 186
Query: 185 IHTKMSPVSVARNASEDARSICMREYGSAPEINIYG------DPDFTFPYVPAHLHLMVF 238
I + V ++A E A+ +C + Y APE+ + D YVP+HL M+F
Sbjct: 187 IDPTCNVADVVKDAYETAKMLCEQYYLVAPELEVEEFNAKAPDKPIQVVYVPSHLFHMLF 246
Query: 239 ELVKNSLRAVQERYMDSDKVSPPIRIIVADGLEDVTIKISDEGGGIPRSGLPKIFTYLYS 298
EL KNS+RA E Y D + P ++ +V G ED++IKISD GGG+P + ++F Y+YS
Sbjct: 247 ELFKNSMRATVELYEDRKEGYPAVKTLVTLGKEDLSIKISDLGGGVPLRKIDRLFNYMYS 306
Query: 299 TARNPLDEHADLGVADSVTTMAGYGYGLPISRLYARYFGGDLQIISMEGYGTDAYLHLSR 358
TA P E +AG+GYGLPISRLYARYF GDL++ SMEG GTDA ++L
Sbjct: 307 TAPRPSLE------PTRAAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLKA 360
Query: 359 L-GDSQEPLP 367
L +S E LP
Sbjct: 361 LSSESFERLP 370
>PDK4_MOUSE (O70571) [Pyruvate dehydrogenase [lipoamide]] kinase
isozyme 4, mitochondrial precursor (EC 2.7.1.99)
(Pyruvate dehydrogenase kinase isoform 4)
Length = 412
Score = 227 bits (579), Expect = 3e-59
Identities = 138/367 (37%), Positives = 211/367 (56%), Gaps = 24/367 (6%)
Query: 13 QEVHKWGCLKQTGVSLRYMMEFGSQPTDKNLLISAQFLQKELAIRIARRAIELESLPYGL 72
+EV + + +S++ +++FGS+ + S FL++EL +R+A E++ LP L
Sbjct: 22 REVELFSRYSPSPLSMKQLLDFGSENACERT--SFAFLRQELPVRLANILKEIDILPDRL 79
Query: 73 SKKPAILKVRDWYVDSFRDIRSCPEV--KDMKDEREFTDVIKAIKVRHNNVVPTMALGVQ 130
P++ V+ WY+ S D+ E +D K EF D + ++ RH+NVVPTMA G+
Sbjct: 80 VNTPSVQLVKSWYIQSLMDLVEFHEKSPEDQKALSEFVDTLVKVRNRHHNVVPTMAQGIL 139
Query: 131 QLKKELKTKIDSEDLVEIHEFLDRFYLSRIGVRMLIGQHVELHNPNPP--PHVVGYIHTK 188
+ K +D + FLDRFY++RI RML+ QH+ + + + P +G I
Sbjct: 140 EYKDTCT--VDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSKTGNPSHIGSIDPN 197
Query: 189 MSPVSVARNASEDARSICMREYGSAPEINIY-------GDPDFTFPYVPAHLHLMVFELV 241
V+V ++A E A+ +C + Y ++PE+N+ G P YVP+HLH M+FEL
Sbjct: 198 CDVVAVVQDAFECAKMLCDQYYLTSPELNLTQVNGKFPGQP-IHIVYVPSHLHHMLFELF 256
Query: 242 KNSLRAVQERYMDSDKVSPPIRIIVADGLEDVTIKISDEGGGIPRSGLPKIFTYLYSTAR 301
KN++RA E + ++P + V G ED+TIKISD GGG+P ++F+Y YSTA
Sbjct: 257 KNAMRATVEHQENRPSLTP-VEATVVLGKEDLTIKISDRGGGVPLRITDRLFSYTYSTAP 315
Query: 302 NPLDEHADLGVADSVTTMAGYGYGLPISRLYARYFGGDLQIISMEGYGTDAYLHLSRL-G 360
P+ +++ +AG+GYGLPISRLYA+YF GDL + SM GYGTDA ++L L
Sbjct: 316 TPVMDNS------RNAPLAGFGYGLPISRLYAKYFQGDLNLYSMSGYGTDAIIYLKALSS 369
Query: 361 DSQEPLP 367
+S E LP
Sbjct: 370 ESVEKLP 376
>PDK4_SPETR (O88345) [Pyruvate dehydrogenase [lipoamide]] kinase
isozyme 4, mitochondrial precursor (EC 2.7.1.99)
(Pyruvate dehydrogenase kinase isoform 4)
Length = 412
Score = 227 bits (578), Expect = 4e-59
Identities = 136/367 (37%), Positives = 214/367 (58%), Gaps = 24/367 (6%)
Query: 13 QEVHKWGCLKQTGVSLRYMMEFGSQPTDKNLLISAQFLQKELAIRIARRAIELESLPYGL 72
+EV + + +S++ +++FGS + S FL++EL +R+A E++ LP L
Sbjct: 22 REVELFSRYSPSPLSMKQLLDFGSDNACERTSFS--FLRQELPVRLANILKEIDVLPDRL 79
Query: 73 SKKPAILKVRDWYVDSFRDIRSCPEV--KDMKDEREFTDVIKAIKVRHNNVVPTMALGVQ 130
+ ++ V+ WY+ S ++ E +D K+ +F D + ++ RH+NVVPTMA G+
Sbjct: 80 TNTSSVQLVKSWYIQSLMELVEFHEKSPEDQKNLSDFVDTLIKVRNRHHNVVPTMAQGIL 139
Query: 131 QLKKELKTKIDSEDLVEIHEFLDRFYLSRIGVRMLIGQHVELHNPNPP--PHVVGYIHTK 188
+ K +D + FLDRFY++RI RML+ QH+ + + + P +G I K
Sbjct: 140 EYKDTCT--VDPVTNQSLQYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPSHIGSIDPK 197
Query: 189 MSPVSVARNASEDARSICMREYGSAPEINIY-------GDPDFTFPYVPAHLHLMVFELV 241
V+V ++A E ++ +C + Y ++PE+ + G P YVP+HLH M+FEL
Sbjct: 198 CDVVAVIQDAFESSKMLCDQYYLTSPELKLTQVNGKFPGQP-IHIVYVPSHLHHMLFELF 256
Query: 242 KNSLRAVQERYMDSDKVSPPIRIIVADGLEDVTIKISDEGGGIPRSGLPKIFTYLYSTAR 301
KN++RA ER +S P+ +IV G ED+TIKISD GGG+P ++F+Y+YSTA
Sbjct: 257 KNAMRATVER-QESWPSLTPVEVIVVLGKEDLTIKISDRGGGVPLRITDRLFSYMYSTAP 315
Query: 302 NPLDEHADLGVADSVTTMAGYGYGLPISRLYARYFGGDLQIISMEGYGTDAYLHLSRL-G 360
P+ +++ +AG+GYGLPISRLYA+YF GDL + S+ GYGTDA ++L L
Sbjct: 316 TPVMDNS------RNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLKALSS 369
Query: 361 DSQEPLP 367
+S E LP
Sbjct: 370 ESVEKLP 376
>PDK_ASCSU (O02623) [Pyruvate dehydrogenase [lipoamide]] kinase,
mitochondrial precursor (EC 2.7.1.99) (Pyruvate
dehydrogenase kinase)
Length = 399
Score = 224 bits (570), Expect = 3e-58
Identities = 139/372 (37%), Positives = 218/372 (58%), Gaps = 25/372 (6%)
Query: 7 FSKSLLQEVHKWGCLKQTGVSLRYMMEFGSQPTDKNLLISAQFLQKELAIRIARRAIELE 66
F+ ++ +++ + + + ++++ ++FG T K+ + FL+ EL +R+A E+
Sbjct: 11 FTSAIARKLEHYSQFQPSSLTIQQYLDFGQTGTMKSSFL---FLKNELLVRLANIMQEIS 67
Query: 67 SLPYGLSKKPAILKVRDWYVDSFRDIRSCPEVKDMKD-EREFTDVIKAIKVRHNNVVPTM 125
LP L K P+ V +WY +SF D+ + D +F D ++ I RH+ VV TM
Sbjct: 68 LLPPTLLKMPSRRLVSNWYCESFEDLLQFEHAQVEPDIMSKFNDQLQTILKRHSRVVETM 127
Query: 126 ALGVQQLKKELKTKIDSEDLVEIHEFLDRFYLSRIGVRMLIGQHVELHN---PNPPPHVV 182
A G+ +L++ I SE ++ FLDRFY++RI +RML QH+ + P P H+
Sbjct: 128 AEGLIELRESEGVDIASERGIQY--FLDRFYINRISIRMLQNQHLVVFGVVLPESPRHI- 184
Query: 183 GYIHTKMSPVSVARNASEDARSICMREYGSAP--EINIYGDPDFTFPY----VPAHLHLM 236
G I SV +A E+AR +C R Y +AP ++ ++ + P VP+HL+ +
Sbjct: 185 GCIDPGCDVESVVHDAYENARFLCERYYLTAPGMKLEMHNSVNPGMPISIVAVPSHLYHI 244
Query: 237 VFELVKNSLRAVQERYMDSDKVSPPIRIIVADGLEDVTIKISDEGGGIPRSGLPKIFTYL 296
+FEL KNS+RA E + +D+ PPI+++V G ED++IKISD GGG+ R+ L ++FTY+
Sbjct: 245 MFELFKNSMRATVENH-GADEDLPPIKVMVVRGAEDLSIKISDRGGGVSRTILDRLFTYM 303
Query: 297 YSTARNPLDEHADLGVADSVTTMAGYGYGLPISRLYARYFGGDLQIISMEGYGTDAYLHL 356
YSTA P + +AGYGYGLP+SRLYARYF GD+ ++SMEGYGTDA + L
Sbjct: 304 YSTAPPPPRDGTQ-------PPLAGYGYGLPLSRLYARYFHGDMYLVSMEGYGTDAMIFL 356
Query: 357 SRLG-DSQEPLP 367
+ ++ E LP
Sbjct: 357 KAIPVEASEVLP 368
>PDK4_RAT (O54937) [Pyruvate dehydrogenase [lipoamide]] kinase
isozyme 4, mitochondrial precursor (EC 2.7.1.99)
(Pyruvate dehydrogenase kinase isoform 4)
Length = 412
Score = 224 bits (570), Expect = 3e-58
Identities = 136/367 (37%), Positives = 209/367 (56%), Gaps = 24/367 (6%)
Query: 13 QEVHKWGCLKQTGVSLRYMMEFGSQPTDKNLLISAQFLQKELAIRIARRAIELESLPYGL 72
+EV + + +S++ +++FGS+ + S FL++EL +R+A E++ LP L
Sbjct: 22 REVELFSRYSPSPLSMKQLLDFGSENACERTSFS--FLRQELPVRLANILKEIDILPEHL 79
Query: 73 SKKPAILKVRDWYVDSFRDIRSCPEV--KDMKDEREFTDVIKAIKVRHNNVVPTMALGVQ 130
P++ V+ WY+ S D+ E +D K +F D + ++ RH+NVVPTMA G+
Sbjct: 80 VNTPSVQLVKSWYIQSLMDLVEFHEKSPEDQKVLSDFVDTLVKVRNRHHNVVPTMAQGIL 139
Query: 131 QLKKELKTKIDSEDLVEIHEFLDRFYLSRIGVRMLIGQHVELHNPNPP--PHVVGYIHTK 188
+ K +D + FLDRFY++RI RML+ QH+ + + + P +G I
Sbjct: 140 EYKDNCT--VDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSKTGNPSHIGSIDPN 197
Query: 189 MSPVSVARNASEDARSICMREYGSAPEINIY-------GDPDFTFPYVPAHLHLMVFELV 241
V+V +A E A+ +C + Y ++PE+ + G P YVP+HLH M+FEL
Sbjct: 198 CDVVAVVEDAFECAKMLCDQYYLTSPELKLTQVNGKFPGQP-IHIVYVPSHLHHMLFELF 256
Query: 242 KNSLRAVQERYMDSDKVSPPIRIIVADGLEDVTIKISDEGGGIPRSGLPKIFTYLYSTAR 301
KN++RA E + ++ P+ V G ED+TIKISD GGG+P ++F+Y YSTA
Sbjct: 257 KNAMRATVE-HQENRPFLTPVEATVVLGKEDLTIKISDRGGGVPLRITDRLFSYTYSTAP 315
Query: 302 NPLDEHADLGVADSVTTMAGYGYGLPISRLYARYFGGDLQIISMEGYGTDAYLHLSRL-G 360
P+ +++ +AG+GYGLPISRLYA+YF GDL + SM GYGTDA ++L L
Sbjct: 316 TPVMDNS------RNAPLAGFGYGLPISRLYAKYFQGDLNLYSMSGYGTDAIIYLKALSS 369
Query: 361 DSQEPLP 367
+S E LP
Sbjct: 370 ESIEKLP 376
>BCKD_MOUSE (O55028) [3-methyl-2-oxobutanoate dehydrogenase
[lipoamide]] kinase, mitochondrial precursor (EC
2.7.1.115) (Branched-chain alpha-ketoacid dehydrogenase
kinase) (BCKDHKIN) (BCKD-kinase)
Length = 412
Score = 216 bits (550), Expect = 7e-56
Identities = 122/342 (35%), Positives = 187/342 (54%), Gaps = 16/342 (4%)
Query: 31 MMEFGSQPTDKNLLISAQFLQKELAIRIARRAIELESLPYGLSKKPAILKVRDWYVDSFR 90
M+ G +LL S ++LQ+EL +RIA R SLP+ + P IL V + Y+ +F+
Sbjct: 75 MLYSGRSQDGSHLLKSGRYLQQELPVRIAHRIKGFRSLPFIIGCNPTILHVHELYIRAFQ 134
Query: 91 DIRSCPEVKDMKDEREFTDVIKAIKVRHNNVVPTMALGVQQLKKELKTKIDSEDLVEIHE 150
+ P +KD DE ++ +++ + H +VV +A G+++ +K I E LV
Sbjct: 135 KLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKH----IQDEKLVRY-- 188
Query: 151 FLDRFYLSRIGVRMLIGQHVELHNPNPPPHVVGYIHTKMSPVSVARNASEDARSICMREY 210
FLD+ SR+G+RML H+ LH P VG I T++SP + + AR +C +Y
Sbjct: 189 FLDKTLTSRLGIRMLATHHLALHEDKPD--FVGIICTRLSPKKIIEKWVDFARRLCEHKY 246
Query: 211 GSAPEINIYGDPDFTFPYVPAHLHLMVFELVKNSLRAVQERYMDSDKVSPPIRIIVADGL 270
G+AP + I G FP++P L ++ EL+KN++RA E ++D+ P + I +A+
Sbjct: 247 GNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVITIANND 306
Query: 271 EDVTIKISDEGGGIPRSGLPKIFTYLYSTAR--------NPLDEHADLGVADSVTTMAGY 322
D+ I+ISD GGGI L ++ Y ++TA NPL H D+ M G+
Sbjct: 307 IDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRINPLFGHLDMHSGGQSGPMHGF 366
Query: 323 GYGLPISRLYARYFGGDLQIISMEGYGTDAYLHLSRLGDSQE 364
G+GLP SR YA Y GG LQ+ S++G GTD YL L + +E
Sbjct: 367 GFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREE 408
>BCKD_RAT (Q00972) [3-methyl-2-oxobutanoate dehydrogenase
[lipoamide]] kinase, mitochondrial precursor (EC
2.7.1.115) (Branched-chain alpha-ketoacid dehydrogenase
kinase) (BCKDHKIN) (BCKD-kinase)
Length = 412
Score = 215 bits (548), Expect = 1e-55
Identities = 119/342 (34%), Positives = 187/342 (53%), Gaps = 16/342 (4%)
Query: 31 MMEFGSQPTDKNLLISAQFLQKELAIRIARRAIELESLPYGLSKKPAILKVRDWYVDSFR 90
M+ G +LL S ++LQ+EL +RIA R SLP+ + P IL V + Y+ +F+
Sbjct: 75 MLYSGRSQDGSHLLKSGRYLQQELPVRIAHRIKGFRSLPFIIGCNPTILHVHELYIRAFQ 134
Query: 91 DIRSCPEVKDMKDEREFTDVIKAIKVRHNNVVPTMALGVQQLKKELKTKIDSEDLVEIHE 150
+ P +KD DE ++ +++ + H +VV +A G+++ +K + ED +
Sbjct: 135 KLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHI------EDEKLVRY 188
Query: 151 FLDRFYLSRIGVRMLIGQHVELHNPNPPPHVVGYIHTKMSPVSVARNASEDARSICMREY 210
FLD+ SR+G+RML H+ LH P VG I T++SP + + AR +C +Y
Sbjct: 189 FLDKTLTSRLGIRMLATHHLALHEDKPD--FVGIICTRLSPKKIIEKWVDFARRLCEHKY 246
Query: 211 GSAPEINIYGDPDFTFPYVPAHLHLMVFELVKNSLRAVQERYMDSDKVSPPIRIIVADGL 270
G+AP + I G FP++P L ++ EL+KN++RA E ++D+ P + I +A+
Sbjct: 247 GNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVITIANND 306
Query: 271 EDVTIKISDEGGGIPRSGLPKIFTYLYSTAR--------NPLDEHADLGVADSVTTMAGY 322
D+ I+ISD GGGI L ++ Y ++TA +PL H D+ M G+
Sbjct: 307 VDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGGQSGPMHGF 366
Query: 323 GYGLPISRLYARYFGGDLQIISMEGYGTDAYLHLSRLGDSQE 364
G+GLP SR YA Y GG LQ+ S++G GTD YL L + +E
Sbjct: 367 GFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREE 408
>BCKD_HUMAN (O14874) [3-methyl-2-oxobutanoate dehydrogenase
[lipoamide]] kinase, mitochondrial precursor (EC
2.7.1.115) (Branched-chain alpha-ketoacid dehydrogenase
kinase) (BCKDHKIN) (BCKD-kinase)
Length = 412
Score = 214 bits (546), Expect = 2e-55
Identities = 119/342 (34%), Positives = 187/342 (53%), Gaps = 16/342 (4%)
Query: 31 MMEFGSQPTDKNLLISAQFLQKELAIRIARRAIELESLPYGLSKKPAILKVRDWYVDSFR 90
M+ G +LL SA++LQ+EL +RIA R LP+ + P IL V + Y+ +F+
Sbjct: 75 MLYAGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRCLPFIIGCNPTILHVHELYIRAFQ 134
Query: 91 DIRSCPEVKDMKDEREFTDVIKAIKVRHNNVVPTMALGVQQLKKELKTKIDSEDLVEIHE 150
+ P +KD DE ++ +++ + H +VV +A G+++ +K + ED +
Sbjct: 135 KLTDFPPIKDQADEAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHI------EDEKLVRY 188
Query: 151 FLDRFYLSRIGVRMLIGQHVELHNPNPPPHVVGYIHTKMSPVSVARNASEDARSICMREY 210
FLD+ SR+G+RML H+ LH P VG I T++SP + + AR +C +Y
Sbjct: 189 FLDKTLTSRLGIRMLATHHLALHEDKPD--FVGIICTRLSPKKIIEKWVDFARRLCEHKY 246
Query: 211 GSAPEINIYGDPDFTFPYVPAHLHLMVFELVKNSLRAVQERYMDSDKVSPPIRIIVADGL 270
G+AP + I G FP++P L ++ EL+KN++RA E ++D+ P + I +A+
Sbjct: 247 GNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVITIANND 306
Query: 271 EDVTIKISDEGGGIPRSGLPKIFTYLYSTAR--------NPLDEHADLGVADSVTTMAGY 322
D+ I+ISD GGGI L ++ Y ++TA +PL H D+ M G+
Sbjct: 307 VDLIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGAQSGPMHGF 366
Query: 323 GYGLPISRLYARYFGGDLQIISMEGYGTDAYLHLSRLGDSQE 364
G+GLP SR YA Y GG LQ+ S++G GTD YL L + +E
Sbjct: 367 GFGLPTSRAYAEYLGGSLQLQSLQGIGTDVYLRLRHIDGREE 408
>PDK_CAEEL (Q02332) Probable [pyruvate dehydrogenase [lipoamide]]
kinase, mitochondrial precursor (EC 2.7.1.99) (Pyruvate
dehydrogenase kinase)
Length = 401
Score = 209 bits (531), Expect = 1e-53
Identities = 140/374 (37%), Positives = 209/374 (55%), Gaps = 29/374 (7%)
Query: 7 FSKSLLQEVHKWGCLKQTGVSLRYMMEFGSQPTDKNLLISAQFLQKELAIRIARRAIELE 66
F SL +++ + + + ++++ ++FG T N S FL+ EL +R+A E
Sbjct: 11 FVGSLAKKLDYYSQFQPSSLTIQQYLDFGRIGTSAN---SYTFLKNELLVRLANIMQEFT 67
Query: 67 SLPYGLSKKPAILKVRDWYVDSFRDIRSCPEVKDMKDER--EFTDVIKAIKVRHNNVVPT 124
LP L + P+ V +WY +SF D+ E D E+ F D + + RH +VV T
Sbjct: 68 LLPPKLLQMPSSKMVSNWYAESFEDLLLF-EASDSSPEQVARFNDQLTVVLKRHAHVVET 126
Query: 125 MALGVQQLKKELKTKIDSEDLVEIHEFLDRFYLSRIGVRMLIGQHVELHN---PNPPPHV 181
MA G+ +L++ I SE ++ FLDRFY++RI +RML QH+ + P P HV
Sbjct: 127 MAEGLIELRESDGVDIASEKGIQY--FLDRFYINRISIRMLQNQHLVVFGNVLPESPRHV 184
Query: 182 VGYIHTKMSPVSVARNASEDARSICMREYGSAPEINIY-------GDPDFTFPYVPAHLH 234
G I SV +A E+AR +C R Y ++P + + G P + VP+HL+
Sbjct: 185 -GCIDPACDVESVVYDAFENARFLCDRYYLTSPSMKLEMHNAVEKGKP-ISIVAVPSHLY 242
Query: 235 LMVFELVKNSLRAVQERYMDSDKVSPPIRIIVADGLEDVTIKISDEGGGIPRSGLPKIFT 294
M+FEL KN++RA E Y D P I++ V G ED++IKI D GGG+ R+ L +++
Sbjct: 243 HMMFELFKNAMRATVE-YHGVDDDLPDIKVYVVKGQEDLSIKICDRGGGVSRTILERLYN 301
Query: 295 YLYSTARNPLDEHADLGVADSVTTMAGYGYGLPISRLYARYFGGDLQIISMEGYGTDAYL 354
Y+YSTA P + +AGYGYGLP+SRLYARYF GDL ++SMEG+GTDA +
Sbjct: 302 YMYSTAPPPPRDGTQ-------APLAGYGYGLPLSRLYARYFLGDLFLVSMEGHGTDACI 354
Query: 355 HLSRLG-DSQEPLP 367
+L + ++ E LP
Sbjct: 355 YLKAVPVEASEVLP 368
>YIE2_YEAST (P40530) Hypothetical 45.4 kDa protein in CBR5-NOT3
intergenic region
Length = 394
Score = 92.0 bits (227), Expect = 2e-18
Identities = 71/308 (23%), Positives = 144/308 (46%), Gaps = 26/308 (8%)
Query: 60 RRAIELESLPYGLSKKPAILKVRDWYVDSFRDIRSCPEVKDM----KDEREFTDVIKAIK 115
+R ++ LPY P I + Y+ S + + S ++ K + +FT+++
Sbjct: 90 KRLNAIQRLPYNAVINPHIERTNSLYLKSLQTLLSIAYPYELHNPPKIQAKFTELLDD-- 147
Query: 116 VRHNNVVPTMALGVQQLKKELKTKIDSEDLVEIHEFLDRFYLSRIGVRMLIGQHVELHNP 175
H + + +A G+Q+++ +I +FL+ RI +++L+ ++ L
Sbjct: 148 --HEDAIVVLAKGLQEIQS-------CYPKFQISQFLNFHLKERITMKLLVTHYLSLMAQ 198
Query: 176 NPPP---HVVGYIHTKMSPVSVARNASEDARSICMREYGSAPEINIYGDP--DFTFPYVP 230
N ++G +H + + ++ S+ IC ++ + + P D TF +P
Sbjct: 199 NKGDTNKRMIGILHRDLPIAQLIKHVSDYVNDICFVKFNTQRTPVLIHPPSQDITFTCIP 258
Query: 231 AHLHLMVFELVKNSLRAVQERYMDSDKVSPPIRIIVADGLEDVTIKISDEGGGIPRSGLP 290
L ++ E+ KN+ A + + + + I ++ D +++ ++I D GGGI
Sbjct: 259 PILEYIMTEVFKNAFEA--QIALGKEHMPIEINLLKPDD-DELYLRIRDHGGGITPEVEA 315
Query: 291 KIFTYLYST--ARNPLDEHADLGVADSVTTMAGYGYGLPISRLYARYFGGDLQIISMEGY 348
+F Y YST ++ E DL + + ++G G+GLP+ + Y FGG + + S+ G+
Sbjct: 316 LMFNYSYSTHTQQSADSESTDLP-GEQINNVSGMGFGLPMCKTYLELFGGKIDVQSLLGW 374
Query: 349 GTDAYLHL 356
GTD Y+ L
Sbjct: 375 GTDVYIKL 382
>YGF9_YEAST (P53170) Hypothetical 51.9 kDa protein in PYC1-UBC2
intergenic region
Length = 445
Score = 89.7 bits (221), Expect = 1e-17
Identities = 67/272 (24%), Positives = 127/272 (46%), Gaps = 18/272 (6%)
Query: 26 VSLRYMMEF---GSQPTDKNLLISAQFLQKELAIRIARRAIELESLPYGLSKKPAILKVR 82
VSL + ++ ++ T ++ S +F+++EL IRIA + +L+ LP+ + ++V
Sbjct: 80 VSLTQLAQYYDDSTKLTRTKIINSGKFVKEELVIRIAHKLNQLQQLPFNVVNNFHFVQVY 139
Query: 83 DWYVDSFRDIRSCPEVKDMKDEREFTDVIKAIKVRHNNV-VPTMALGVQQLKKELKTKID 141
+ Y + F R P ++ ++D +F D IK + N + +P + +G + T +D
Sbjct: 140 ESYYNIFESFRKYPTIRTLEDASQFADFIKNMLEGFNTLNLPHLIMGALEC-----TILD 194
Query: 142 SEDLVEIHEFLDRFYLSRIGVRMLIGQHV-----ELHNPNPPPHVVGYIHTKMSPVSVAR 196
++ + L +RI R+++ +HV V+G I + S
Sbjct: 195 LYPREKMDQLLSDLLRARISRRLIVEEHVVYTANYTSGKEENTLVLGDIFQECSAKKYLL 254
Query: 197 NASEDARSICMREYGS---APEINIYGDPDFTFPYVPAHLHLMVFELVKNSLRAVQERYM 253
ASE+++ Y PE I GD +F ++P HL ++ E+++N+ A + Y+
Sbjct: 255 EASEESQKFIQDMYFKDIPMPEFIIEGDTQLSFYFLPTHLKYLLGEILRNTYEATMKHYI 314
Query: 254 DSDKVSP-PIRIIVADGLEDVTIKISDEGGGI 284
P PI + V E +ISD+ GG+
Sbjct: 315 RKGLEKPEPIIVTVVSNDESYLFRISDKAGGV 346
>VIRA_AGRTU (P07168) Wide host range virA protein (EC 2.7.3.-) (WHR
virA)
Length = 829
Score = 45.8 bits (107), Expect = 2e-04
Identities = 45/147 (30%), Positives = 66/147 (44%), Gaps = 31/147 (21%)
Query: 230 PAHLHLMVFELVKNSLRAVQERYMDSDKVSP---PIRIIVADGL----EDVTIKISDEGG 282
P L ++ + KN+ +A+ +S P++ I+A G+ + V + ISD GG
Sbjct: 573 PLELQQVLINICKNASQAMTANGQIDIIISQAFLPVKKILAHGVMPPGDYVLLSISDNGG 632
Query: 283 GIPRSGLPKIFTYLYST-ARNPLDEHADLGVADSVTTMAGYGYGLPISRLYARYFGGDLQ 341
GIP + LP IF +ST ARN G G GL + F G +
Sbjct: 633 GIPEAVLPHIFEPFFSTRARN-----------------GGTGLGLASVHGHISAFAGYID 675
Query: 342 IISMEGYGT--DAYLHLSRLGDSQEPL 366
+ S G+GT D YL S S+EP+
Sbjct: 676 VSSTVGHGTRFDIYLPPS----SKEPV 698
>VIRA_AGRT9 (P10799) Wide host range virA protein (EC 2.7.3.-) (WHR
virA)
Length = 829
Score = 44.7 bits (104), Expect = 4e-04
Identities = 44/147 (29%), Positives = 66/147 (43%), Gaps = 31/147 (21%)
Query: 230 PAHLHLMVFELVKNSLRAVQERYMDSDKVSP---PIRIIVADGL----EDVTIKISDEGG 282
P L ++ + KN+ +A+ +S P++ I+A G+ + V + ISD GG
Sbjct: 573 PLELQQVLINICKNASQAMTANGQIDIIISQAFLPVKKILAHGVMPPGDYVLLSISDNGG 632
Query: 283 GIPRSGLPKIFTYLYST-ARNPLDEHADLGVADSVTTMAGYGYGLPISRLYARYFGGDLQ 341
GIP + LP IF ++T ARN G G GL + F G +
Sbjct: 633 GIPEAVLPHIFEPFFTTRARN-----------------GGTGLGLASVHGHISAFAGYID 675
Query: 342 IISMEGYGT--DAYLHLSRLGDSQEPL 366
+ S G+GT D YL S S+EP+
Sbjct: 676 VSSTVGHGTRFDIYLPPS----SKEPV 698
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.320 0.139 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,316,828
Number of Sequences: 164201
Number of extensions: 1945066
Number of successful extensions: 4687
Number of sequences better than 10.0: 96
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 62
Number of HSP's that attempted gapping in prelim test: 4544
Number of HSP's gapped (non-prelim): 101
length of query: 367
length of database: 59,974,054
effective HSP length: 112
effective length of query: 255
effective length of database: 41,583,542
effective search space: 10603803210
effective search space used: 10603803210
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Medicago: description of AC146757.7