BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC146747.6 + phase: 0 
         (498 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

CRK7_HUMAN (Q9NYV4) Cell division cycle 2-related protein kinase...   278  2e-74
CDL5_HUMAN (Q14004) Cell division cycle 2-like protein kinase 5 ...   267  5e-71
CDK9_SCHPO (Q96WV9) Serine/threonine-protein kinase cdk9 (EC 2.7...   261  4e-69
CDKA_HUMAN (Q15131) Cell division protein kinase 10 (EC 2.7.1.37...   244  4e-64
CDK9_CAEEL (P46551) Putative cell division protein kinase 9 homo...   244  4e-64
CTK1_YEAST (Q03957) CTD kinase alpha subunit (EC 2.7.1.-) (CTD k...   236  1e-61
CDK9_HUMAN (P50750) Cell division protein kinase 9 (EC 2.7.1.37)...   236  1e-61
CDL1_HUMAN (P21127) PITSLRE serine/threonine-protein kinase CDC2...   227  5e-59
CDL1_RAT (P46892) PITSLRE serine/threonine-protein kinase CDC2L1...   226  1e-58
CDL1_MOUSE (P24788) PITSLRE serine/threonine-protein kinase CDC2...   223  9e-58
YP62_CAEEL (Q09437) Putative serine/threonine-protein kinase B04...   223  1e-57
CDL2_HUMAN (Q9UQ88) PITSLRE serine/threonine-protein kinase CDC2...   223  1e-57
CDK2_CARAU (P43450) Cell division protein kinase 2 (EC 2.7.1.37)      223  1e-57
CDK2_CRIGR (O55076) Cell division protein kinase 2 (EC 2.7.1.37)      222  2e-57
CDK2_HUMAN (P24941) Cell division protein kinase 2 (EC 2.7.1.37)...   221  3e-57
CDK2_RAT (Q63699) Cell division protein kinase 2 (EC 2.7.1.37)        221  3e-57
CC2A_ARATH (P24100) Cell division control protein 2 homolog A (E...   221  4e-57
CC2A_ANTMA (Q38772) Cell division control protein 2 homolog A (E...   221  4e-57
CC28_CANAL (P43063) Cell division control protein 28 (EC 2.7.1.37)    221  4e-57
CC22_MEDSA (Q05006) Cell division control protein 2 homolog 2 (E...   221  4e-57

>CRK7_HUMAN (Q9NYV4) Cell division cycle 2-related protein kinase 7
            (EC 2.7.1.37) (CDC2-related protein kinase 7) (CrkRS)
          Length = 1490

 Score =  278 bits (711), Expect = 2e-74
 Identities = 155/339 (45%), Positives = 202/339 (58%), Gaps = 16/339 (4%)

Query: 26   DWTPRRANSFEKLAKIGQGTYSNVYKAKDLVTGKIVALKKVRFDNLEPESVKFMA-REIL 84
            DW  R  + F+ +  IG+GTY  VYKA+D  TG++VALKKVR DN E E     A REI 
Sbjct: 718  DWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGELVALKKVRLDN-EKEGFPITAIREIK 776

Query: 85   VLRKLDHPNVVKLEGLVTSRMSC--------SLYLVFEYMEHDLAGLSAGQGVKFTEPQV 136
            +LR+L H +VV ++ +VT +           + YLVFEYM+HDL GL     V F+E  +
Sbjct: 777  ILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHI 836

Query: 137  KCFMKQLLSGLEHCHSRGVLHRDIKGSNLLIDNEGILKIADFGLATFYNPNKKQSMTSRV 196
            K FMKQL+ GLE+CH +  LHRDIK SN+L++N G +K+ADFGLA  YN  + +  T++V
Sbjct: 837  KSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKV 896

Query: 197  VTLWYRPPELLLGATFYGVGIDLWSAGCILAELLAGKPIMPGRTEVEQLHKIFKLCGSPA 256
            +TLWYRPPELLLG   Y   ID+WS GCIL EL   KPI     E+ QL  I +LCGSP 
Sbjct: 897  ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPC 956

Query: 257  EEYWRK-HKLPNATIFKPQQPYKRCISETFKDFPPSSLPLIDSLLAIDPDRRGTASAALN 315
               W    KLP     KP++ Y+R + E F   P ++L L+D +L +DP +R TA   L 
Sbjct: 957  PAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQ 1016

Query: 316  HEFF-TTEPYACEPSSLPKYPPSKELDVKMRDEEARRQK 353
             +F    E     P  LP +    EL  K R    RRQ+
Sbjct: 1017 SDFLKDVELSKMAPPDLPHWQDCHELWSKKR----RRQR 1051


>CDL5_HUMAN (Q14004) Cell division cycle 2-like protein kinase 5 (EC
           2.7.1.37) (Cholinesterase-related cell division
           controller) (CDC2-related protein kinase 5)
          Length = 418

 Score =  267 bits (682), Expect = 5e-71
 Identities = 143/312 (45%), Positives = 191/312 (60%), Gaps = 12/312 (3%)

Query: 26  DWTPRRANSFEKLAKIGQGTYSNVYKAKDLVTGKIVALKKVRFDNLEPESVKFMA-REIL 84
           DW     + F+ +  IG+GTY  VYKA+D  TG++VALKKVR DN E E     A REI 
Sbjct: 82  DWGKLCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDN-EKEGFPITAIREIK 140

Query: 85  VLRKLDHPNVVKLEGLVTSRMSC--------SLYLVFEYMEHDLAGLSAGQGVKFTEPQV 136
           +LR+L H +++ ++ +VT +           + YLVFEYM+HDL GL     V F E  +
Sbjct: 141 ILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFYENHI 200

Query: 137 KCFMKQLLSGLEHCHSRGVLHRDIKGSNLLIDNEGILKIADFGLATFYNPNKKQSMTSRV 196
           K FM+QL+ GL++CH +  LHRDIK SN+L++N G +K+ADFGLA  Y+  + +  T++V
Sbjct: 201 KSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKV 260

Query: 197 VTLWYRPPELLLGATFYGVGIDLWSAGCILAELLAGKPIMPGRTEVEQLHKIFKLCGSPA 256
           +TLWYRPPELLLG   Y   ID+WS GCIL EL   KPI     E+ QL  I ++CGSP 
Sbjct: 261 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPC 320

Query: 257 EEYWRK-HKLPNATIFKPQQPYKRCISETFKDFPPSSLPLIDSLLAIDPDRRGTASAALN 315
              W    KLP     KP++ Y+R + E F   P ++L L D +LA+DP +R TA  AL 
Sbjct: 321 PAVWPDVIKLPYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQ 380

Query: 316 HEFF-TTEPYAC 326
            EF    EP  C
Sbjct: 381 CEFLRDVEPSKC 392


>CDK9_SCHPO (Q96WV9) Serine/threonine-protein kinase cdk9 (EC
           2.7.1.37) (Cyclin-dependent kinase cdk9)
          Length = 591

 Score =  261 bits (666), Expect = 4e-69
 Identities = 155/410 (37%), Positives = 221/410 (53%), Gaps = 42/410 (10%)

Query: 35  FEKLAKIGQGTYSNVYKAKDLVTGKIVALKKVRFDNLEPESVKFMA-REILVLRKLDHPN 93
           +  + K+G+GT+  VYK++    GK+ ALK++   + E E     A REI +L+ + H N
Sbjct: 36  YHLMEKLGEGTFGEVYKSQRRKDGKVYALKRILM-HTEKEGFPITAIREIKILKSIKHEN 94

Query: 94  VVKLEGLVTSRMSC------SLYLVFEYMEHDLAGLSAGQGVKFTEPQVKCFMKQLLSGL 147
           ++ L  +   R         S+Y+V  YM+HDL+GL     VKFTEPQ+KC+MKQL +G 
Sbjct: 95  IIPLSDMTVVRADKKHRRRGSIYMVTPYMDHDLSGLLENPSVKFTEPQIKCYMKQLFAGT 154

Query: 148 EHCHSRGVLHRDIKGSNLLIDNEGILKIADFGLATFYN------------PNKKQSMTSR 195
           ++ H + +LHRD+K +NLLIDN GILKIADFGLA                P  ++  T  
Sbjct: 155 KYLHDQLILHRDLKAANLLIDNHGILKIADFGLARVITEESYANKNPGLPPPNRREYTGC 214

Query: 196 VVTLWYRPPELLLGATFYGVGIDLWSAGCILAELLAGKPIMPGRTEVEQLHKIFKLCGSP 255
           VVT WYR PELLLG   Y   ID+WS GCI+AE+  G+PI+ G ++++QL KIF+LCGSP
Sbjct: 215 VVTRWYRSPELLLGERRYTTAIDMWSVGCIMAEMYKGRPILQGSSDLDQLDKIFRLCGSP 274

Query: 256 AEEYWRK-HKLPNATIFKPQQPYKRCISETFKDFPPSSLPLIDSLLAIDPDRRGTASAAL 314
            +       KLP     +    + R +   F  F      L  ++L ++PD R +AS AL
Sbjct: 275 TQATMPNWEKLPGCEGVRSFPSHPRTLETAFFTFGKEMTSLCGAILTLNPDERLSASMAL 334

Query: 315 NHEFFTTEPYACEPSSLPKYPPSKELDVKMRDEEARRQKALNGKA--NAVDGAKRVRARE 372
            HE+FTT PY   PS L  Y  S E D + +    R Q+  N  A     +G ++ R   
Sbjct: 335 EHEYFTTPPYPANPSELQSYSASHEYDKRRK----REQRDANSHAFEQTANGKRQFRFMT 390

Query: 373 RGRAIP-----APEANAEIQ----------TNLDRWRVVTHANAKSKSEK 407
           RG + P      P  N++ Q           N+DR R V +   + ++ K
Sbjct: 391 RGPSDPWYGIRRPNYNSQPQYQRGSYNREGGNMDRSRNVNYQPKRQQNFK 440


>CDKA_HUMAN (Q15131) Cell division protein kinase 10 (EC 2.7.1.37)
           (Serine/threonine-protein kinase PISSLRE)
          Length = 360

 Score =  244 bits (623), Expect = 4e-64
 Identities = 135/308 (43%), Positives = 183/308 (58%), Gaps = 4/308 (1%)

Query: 30  RRANSFEKLAKIGQGTYSNVYKAKDLVTGKIVALKKVRFDNLEPESVKFMAREILVLRKL 89
           R    FEKL +IG+GTY  VY+A+D  T +IVALKKVR D  +        REI +L +L
Sbjct: 34  RSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRL 93

Query: 90  DHPNVVKLEGLVTSRMSCSLYLVFEYMEHDLAGLSAGQGVKFTEPQVKCFMKQLLSGLEH 149
            HPN+V+L+ +V      S++LV  Y E DLA L       F+E QVKC + Q+L GL++
Sbjct: 94  RHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQY 153

Query: 150 CHSRGVLHRDIKGSNLLIDNEGILKIADFGLATFYNPNKKQSMTSRVVTLWYRPPELLLG 209
            H   ++HRD+K SNLL+ ++G +K ADFGLA  Y    K  MT +VVTLWYR PELLLG
Sbjct: 154 LHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVK-PMTPKVVTLWYRAPELLLG 212

Query: 210 ATFYGVGIDLWSAGCILAELLAGKPIMPGRTEVEQLHKIFKLCGSPAEEYWRK-HKLPNA 268
            T     ID+W+ GCILAELLA +P++PG +E+ Q+  I +L G+P+E  W    KLP  
Sbjct: 213 TTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLV 272

Query: 269 TIFK-PQQPYKRCISETFKDFPPSSLPLIDSLLAIDPDRRGTASAALNHEFFTTEPYACE 327
             +   +QPY   +   F     + L L+  L   DP +R TA   L   +F  +P  CE
Sbjct: 273 GQYSLRKQPYNN-LKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKEKPLPCE 331

Query: 328 PSSLPKYP 335
           P  +P +P
Sbjct: 332 PELMPTFP 339


>CDK9_CAEEL (P46551) Putative cell division protein kinase 9 homolog
           (EC 2.7.1.37)
          Length = 730

 Score =  244 bits (623), Expect = 4e-64
 Identities = 151/397 (38%), Positives = 222/397 (55%), Gaps = 19/397 (4%)

Query: 27  WTPRRANSFEKLAKIGQGTYSNVYKAKDLVTGKIVALKKVRFDNLEPESVKFMA-REILV 85
           W       +  L +IG+GTY  VYKA + +TG+ VALK+VR +N E E     A REI +
Sbjct: 303 WYKTNLTHYTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLEN-EKEGFPITAIREIKI 361

Query: 86  LRKLDHPNVVKLEGLVTSRMS--------CSLYLVFEYMEHDLAGL-SAGQGVKFTEPQV 136
           LR+L H N+V+L  +V   +S         + YLVFEY++HDL GL  + + V F + Q+
Sbjct: 362 LRQLHHKNIVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQI 421

Query: 137 KCFMKQLLSGLEHCHSRGVLHRDIKGSNLLIDNEGILKIADFGLATFYNPNKKQSMTSRV 196
               KQLL GL + H+ G LHRDIK SN+L++N+G LKIAD GLA  +   + +  T+RV
Sbjct: 422 CSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLWE-KESRLYTNRV 480

Query: 197 VTLWYRPPELLLGATFYGVGIDLWSAGCILAELLAGKPIMPGRTEVEQLHKIFKLCGSPA 256
           +TLWYRPPELLLG   YG  ID+WS GC+L EL   KP+  G  E  QL  I K+CGSP 
Sbjct: 481 ITLWYRPPELLLGDERYGPAIDVWSTGCMLGELFTRKPLFNGNNEFGQLELISKVCGSPN 540

Query: 257 EEYWRK-HKLPNATIFKPQQPYKRCISETFKD-FPPSSLPLIDSLLAIDPDRRGTASAAL 314
            + W +  +L     F+ ++ Y+R I E F+   P  ++ L+D +L ++P++R +A  AL
Sbjct: 541 VDNWPELTELVGWNTFRMKRTYQRRIREEFEHIMPREAVDLLDKMLTLNPEKRISAKEAL 600

Query: 315 NHEFF-TTEPYACEPSSLPKYPPSKELDVKMRDEEARRQKALNGKANAVDGAKRVRARER 373
           NH +  + E    +P  LP++    E+  K + + AR  +   G + +      +RA   
Sbjct: 601 NHPWIRSLEHTTVQPLKLPQHQDCHEMWSKKQKKSARLGRQAEGSSGS---GHSIRATSH 657

Query: 374 GRAIPAPEANAEIQTNLDRWRVVTHANAKSKSEKFPP 410
            RA P   +    ++N        H ++   +   PP
Sbjct: 658 PRA-PTQPSTTTTKSNGSSNHHHHHHHSHHHASSLPP 693


>CTK1_YEAST (Q03957) CTD kinase alpha subunit (EC 2.7.1.-) (CTD
           kinase 58 kDa subunit) (CTDK-I alpha subunit)
          Length = 528

 Score =  236 bits (602), Expect = 1e-61
 Identities = 138/332 (41%), Positives = 192/332 (57%), Gaps = 13/332 (3%)

Query: 30  RRANSFEKLAKIGQGTYSNVYKAKDLVTGKIVALKKVRFDNLEPESVKFMAREILVLRKL 89
           R  + + ++ ++G+GTY  VYKAK+  T K+VALKK+R             REI +L+  
Sbjct: 178 RSTSVYLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSF 237

Query: 90  DHPNVVKLEGLVTSRMSCSLYLVFEYMEHDLAGLSAGQGVKFTEPQVKCFMKQLLSGLEH 149
           DHPNV  ++ ++      ++Y++FEY ++DL+GL   + V+ +  Q K   KQLL G+E+
Sbjct: 238 DHPNVSTIKEIMVESQK-TVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEY 296

Query: 150 CHSRGVLHRDIKGSNLLIDNEGILKIADFGLATFYNPNKKQSMTSRVVTLWYRPPELLLG 209
            H   +LHRD+KGSN+LIDN+G LKI DFGLA     N +   T+RV+TLWYRPPELLLG
Sbjct: 297 LHDNKILHRDVKGSNILIDNQGNLKITDFGLAR--KMNSRADYTNRVITLWYRPPELLLG 354

Query: 210 ATFYGVGIDLWSAGCILAELLAGKPIMPGRTEVEQLHKIFKLCGSPAEEYW-RKHKLPNA 268
            T YG  +D+W  GC+L EL     I  G  E+EQ+  IFK+ G+P    W   + +P  
Sbjct: 355 TTNYGTEVDMWGCGCLLVELFNKTAIFQGSNELEQIESIFKIMGTPTINSWPTLYDMPWF 414

Query: 269 TIFKPQQ--PYKRCISETFKDFPPSS--LPLIDSLLAIDPDRRGTASAALNHEFFTTEPY 324
            +  PQQ   Y    SE FK   PSS  L L  +LL  D  +R +A+ AL  ++F  EP 
Sbjct: 415 FMIMPQQTTKYVNNFSEKFKSVLPSSKCLQLAINLLCYDQTKRFSATEALQSDYFKEEPK 474

Query: 325 ACEPSSLPKYPPSKELDVKMRDEEARRQKALN 356
             EP  L       E +VK+    AR+QK  N
Sbjct: 475 P-EPLVLDGLVSCHEYEVKL----ARKQKRPN 501


>CDK9_HUMAN (P50750) Cell division protein kinase 9 (EC 2.7.1.37)
           (Serine/threonine-protein kinase PITALRE) (C-2K)
          Length = 372

 Score =  236 bits (602), Expect = 1e-61
 Identities = 141/306 (46%), Positives = 190/306 (62%), Gaps = 18/306 (5%)

Query: 33  NSFEKLAKIGQGTYSNVYKAKDLVTGKIVALKKVRFDNLEPESVKFMA-REILVLRKLDH 91
           + +EKLAKIGQGT+  V+KA+   TG+ VALKKV  +N E E     A REI +L+ L H
Sbjct: 17  SKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMEN-EKEGFPITALREIKILQLLKH 75

Query: 92  PNVVKLEGLVTSRMS----C--SLYLVFEYMEHDLAGLSAGQGVKFTEPQVKCFMKQLLS 145
            NVV L  +  ++ S    C  S+YLVF++ EHDLAGL +   VKFT  ++K  M+ LL+
Sbjct: 76  ENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLN 135

Query: 146 GLEHCHSRGVLHRDIKGSNLLIDNEGILKIADFGLATFYNPNKKQS---MTSRVVTLWYR 202
           GL + H   +LHRD+K +N+LI  +G+LK+ADFGLA  ++  K       T+RVVTLWYR
Sbjct: 136 GLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWYR 195

Query: 203 PPELLLGATFYGVGIDLWSAGCILAELLAGKPIMPGRTEVEQLHKIFKLCGSPAEEYWRK 262
           PPELLLG   YG  IDLW AGCI+AE+    PIM   TE  QL  I +LCGS   E W  
Sbjct: 196 PPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQANTEQHQLALISQLCGSITPEVW-- 253

Query: 263 HKLPNATIFKPQQ---PYKRCISETFKDF--PPSSLPLIDSLLAIDPDRRGTASAALNHE 317
             + N  +++  +     KR + +  K +   P +L LID LL +DP +R  +  ALNH+
Sbjct: 254 PNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHD 313

Query: 318 FFTTEP 323
           FF ++P
Sbjct: 314 FFWSDP 319


>CDL1_HUMAN (P21127) PITSLRE serine/threonine-protein kinase CDC2L1
           (EC 2.7.1.37) (Galactosyltransferase associated protein
           kinase p58/GTA) (Cell division cycle 2-like 1) (CLK-1)
           (CDK11) (p58 CLK-1)
          Length = 795

 Score =  227 bits (579), Expect = 5e-59
 Identities = 130/340 (38%), Positives = 184/340 (53%), Gaps = 11/340 (3%)

Query: 2   LDPLSVNQQGWPSWLMAVAGEAIGDWTPRRANSFEKLAKIGQGTYSNVYKAKDLVTGKIV 61
           L P+ + Q+  P +L A+ G        R    F+ L +I +GTY  VY+AKD  T +IV
Sbjct: 413 LSPIELKQE-LPKYLPALQG-------CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIV 464

Query: 62  ALKKVRFDNLEPESVKFMAREILVLRKLDHPNVVKLEGLVTSRMSCSLYLVFEYMEHDLA 121
           ALK+++ +  +        REI  + K  HPN+V +  +V       +Y+V  Y+EHDL 
Sbjct: 465 ALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLK 524

Query: 122 GLSAGQGVKFTEPQVKCFMKQLLSGLEHCHSRGVLHRDIKGSNLLIDNEGILKIADFGLA 181
            L       F   +VK  M QLL G++H H   +LHRD+K SNLL+ + GILK+ DFGLA
Sbjct: 525 SLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLA 584

Query: 182 TFYNPNKKQSMTSRVVTLWYRPPELLLGATFYGVGIDLWSAGCILAELLAGKPIMPGRTE 241
             Y    K + T  VVTLWYR PELLLGA  Y   +D+WS GCI  ELL  KP+ PG++E
Sbjct: 585 REYGSPLK-AYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSE 643

Query: 242 VEQLHKIFKLCGSPAEEYWRKH-KLPNA-TIFKPQQPYKRCISETFKDFPPSSLPLIDSL 299
           ++Q++K+FK  G+P+E+ W  + +LP    +   + PY                 L++  
Sbjct: 644 IDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKF 703

Query: 300 LAIDPDRRGTASAALNHEFFTTEPYACEPSSLPKYPPSKE 339
           L   P RR +A   L HE+F   P   +PS  P +P   E
Sbjct: 704 LTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSE 743


>CDL1_RAT (P46892) PITSLRE serine/threonine-protein kinase CDC2L1
           (EC 2.7.1.37) (Galactosyltransferase associated protein
           kinase p58/GTA) (Cell division cycle 2-like 1)
          Length = 436

 Score =  226 bits (575), Expect = 1e-58
 Identities = 131/340 (38%), Positives = 183/340 (53%), Gaps = 11/340 (3%)

Query: 2   LDPLSVNQQGWPSWLMAVAGEAIGDWTPRRANSFEKLAKIGQGTYSNVYKAKDLVTGKIV 61
           L P+ + Q+  P +L A+ G        R    F+ L +I +GTY  VY+AKD  T +IV
Sbjct: 54  LSPIELKQE-LPKYLPALQG-------CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIV 105

Query: 62  ALKKVRFDNLEPESVKFMAREILVLRKLDHPNVVKLEGLVTSRMSCSLYLVFEYMEHDLA 121
           ALK+++ +  +        REI  + K  HPN+V +  +V       +Y+V  Y+EHDL 
Sbjct: 106 ALKRLKMEKEKEGFPLTSIREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLK 165

Query: 122 GLSAGQGVKFTEPQVKCFMKQLLSGLEHCHSRGVLHRDIKGSNLLIDNEGILKIADFGLA 181
            L       F   +VK  M QLLSG++H H   +LHRD+K SNLL+ + GILK+ DFGLA
Sbjct: 166 SLMETMKQPFLPGEVKTLMIQLLSGVKHLHDNWILHRDLKTSNLLLTHAGILKVGDFGLA 225

Query: 182 TFYNPNKKQSMTSRVVTLWYRPPELLLGATFYGVGIDLWSAGCILAELLAGKPIMPGRTE 241
             Y    K + T  VVTLWYR PELLLGA  Y    D+WS GCI  ELL  KP+ PG+++
Sbjct: 226 REYGSPLK-AYTPVVVTLWYRAPELLLGAKEYSTACDMWSVGCIFGELLTQKPLFPGKSD 284

Query: 242 VEQLHKIFKLCGSPAEEYWRKH-KLPNA-TIFKPQQPYKRCISETFKDFPPSSLPLIDSL 299
           ++Q++KIFK  G+P+E+ W  + +LP    +   + PY                 L++  
Sbjct: 285 IDQINKIFKDIGTPSEKIWPGYSELPAVKKMTFSELPYNNLRKRFGALLSDQGFDLMNKF 344

Query: 300 LAIDPDRRGTASAALNHEFFTTEPYACEPSSLPKYPPSKE 339
           L   P RR  A   L HE+F   P   +PS  P +P   E
Sbjct: 345 LTYYPGRRINAEDGLKHEYFRETPLPIDPSMFPTWPAKSE 384


>CDL1_MOUSE (P24788) PITSLRE serine/threonine-protein kinase CDC2L1
           (EC 2.7.1.37) (Galactosyltransferase associated protein
           kinase p58/GTA) (Cell division cycle 2-like 1)
          Length = 434

 Score =  223 bits (568), Expect = 9e-58
 Identities = 125/312 (40%), Positives = 170/312 (54%), Gaps = 3/312 (0%)

Query: 30  RRANSFEKLAKIGQGTYSNVYKAKDLVTGKIVALKKVRFDNLEPESVKFMAREILVLRKL 89
           R    F+ L +I +GTY  VY+AKD  T +IVALK+++ +  +        REI  + K 
Sbjct: 72  RSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKA 131

Query: 90  DHPNVVKLEGLVTSRMSCSLYLVFEYMEHDLAGLSAGQGVKFTEPQVKCFMKQLLSGLEH 149
            HPN+V +  +V       +Y+V  Y+EHDL  L       F   +VK  M QLLSG++H
Sbjct: 132 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLSGVKH 191

Query: 150 CHSRGVLHRDIKGSNLLIDNEGILKIADFGLATFYNPNKKQSMTSRVVTLWYRPPELLLG 209
            H   +LHRD+K SNLL+ + GILK+ DFGLA  Y    K + T  VVTLWYR PELLLG
Sbjct: 192 LHDNWILHRDLKTSNLLLTHAGILKVGDFGLAREYGSPLK-AYTPVVVTLWYRAPELLLG 250

Query: 210 ATFYGVGIDLWSAGCILAELLAGKPIMPGRTEVEQLHKIFKLCGSPAEEYWRKHK-LPNA 268
           A  Y    D+WS GCI  ELL  KP+ PG+++++Q++KIFK  GSP+E+ W  +  LP  
Sbjct: 251 AKEYSTACDMWSVGCIFGELLTQKPLFPGKSDIDQINKIFKDLGSPSEKIWPGYNDLPAV 310

Query: 269 -TIFKPQQPYKRCISETFKDFPPSSLPLIDSLLAIDPDRRGTASAALNHEFFTTEPYACE 327
             +   + PY                 L++  L   P RR  A   L HE+F   P   +
Sbjct: 311 KKMTFSEIPYNNLRKRFGALLSDQGFDLMNKFLTYYPGRRINAEDGLKHEYFRETPLPID 370

Query: 328 PSSLPKYPPSKE 339
           PS  P +P   E
Sbjct: 371 PSMFPTWPAKSE 382


>YP62_CAEEL (Q09437) Putative serine/threonine-protein kinase
           B0495.2 (EC 2.7.1.37)
          Length = 719

 Score =  223 bits (567), Expect = 1e-57
 Identities = 131/327 (40%), Positives = 192/327 (58%), Gaps = 27/327 (8%)

Query: 30  RRANSFEKLAKIGQGTYSNVYKAKDLVTGKIVALKKVRFDNLEPESVKFMA-REILVLRK 88
           R  + +E + ++ +GT+  VY+ KD  T +IVALK+++ +  E E     A REI +L K
Sbjct: 351 RNIDEYECVNRVDEGTFGVVYRGKDKRTDEIVALKRLKMEK-EKEGFPITALREINMLLK 409

Query: 89  L-DHPNVVKLEGLVTSRMSCSLYLVFEYMEHDLAGL---SAGQGVKFTEPQVKCFMKQLL 144
             +HPN+V ++ ++       +Y+  E++EHD+  L    + +  +F+  + K  ++QLL
Sbjct: 410 AGNHPNIVNVKEILLGSNMDKIYMAMEFVEHDMKSLLDTMSRRNKRFSIGEQKTLLQQLL 469

Query: 145 SGLEHCHSRGVLHRDIKGSNLLIDNEGILKIADFGLATFY-NPNKKQSMTSRVVTLWYRP 203
           SG+EH H   +LHRD+K SNLL+ ++GILKIADFGLA  Y +P KK   TS VVTLWYR 
Sbjct: 470 SGIEHMHKLWILHRDLKTSNLLMSHKGILKIADFGLAREYGDPLKK--FTSIVVTLWYRS 527

Query: 204 PELLLGATFYGVGIDLWSAGCILAELLAGKPIMPGRTEVEQLHKIFKLCGSPAEEYWRKH 263
           PELLLG   Y   +D+WS GCI+AE +  KP+ PGR E+EQ+ KIF   G+P E  W   
Sbjct: 528 PELLLGTRLYSTPVDMWSVGCIMAEFILLKPLFPGRGELEQIKKIFMEMGTPTESIW--- 584

Query: 264 KLPNAT-------IFKPQQPY----KRCISETFKDFPPSSLPLIDSLLAIDPDRRGTASA 312
             P  T       +   + PY    KR ++    +   +   L++ LL +DP  R +A+ 
Sbjct: 585 --PGVTELDGWKALTFEKYPYNQLRKRFLAGRLLN--DTGFKLLNGLLTLDPKNRFSATQ 640

Query: 313 ALNHEFFTTEPYACEPSSLPKYPPSKE 339
           AL+HE+FT EPY   P   P +P   E
Sbjct: 641 ALDHEWFTEEPYPVPPEEFPTFPAKSE 667


>CDL2_HUMAN (Q9UQ88) PITSLRE serine/threonine-protein kinase CDC2L2
           (EC 2.7.1.37) (Galactosyltransferase associated protein
           kinase p58/GTA) (Cell division cycle 2-like 2) (CDK11)
          Length = 780

 Score =  223 bits (567), Expect = 1e-57
 Identities = 128/338 (37%), Positives = 181/338 (52%), Gaps = 11/338 (3%)

Query: 4   PLSVNQQGWPSWLMAVAGEAIGDWTPRRANSFEKLAKIGQGTYSNVYKAKDLVTGKIVAL 63
           P+ + Q+  P +L A+ G        R    F+ L +I +GTY  VY+AKD  T +IVAL
Sbjct: 400 PIELKQE-LPKYLPALQG-------CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVAL 451

Query: 64  KKVRFDNLEPESVKFMAREILVLRKLDHPNVVKLEGLVTSRMSCSLYLVFEYMEHDLAGL 123
           K+++ +  +        REI  + K  HPN+V +  +V       +Y+V  Y+EHDL  L
Sbjct: 452 KRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSL 511

Query: 124 SAGQGVKFTEPQVKCFMKQLLSGLEHCHSRGVLHRDIKGSNLLIDNEGILKIADFGLATF 183
                  F   +VK  M QLL G++H H   +LHRD+K SNLL+ + GILK+ DFGLA  
Sbjct: 512 METMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLARE 571

Query: 184 YNPNKKQSMTSRVVTLWYRPPELLLGATFYGVGIDLWSAGCILAELLAGKPIMPGRTEVE 243
           Y    K + T  VVT WYR PELLLGA  Y   +D+WS GCI  ELL  KP+ PG +E++
Sbjct: 572 YGSPLK-AYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEID 630

Query: 244 QLHKIFKLCGSPAEEYWRKH-KLPNA-TIFKPQQPYKRCISETFKDFPPSSLPLIDSLLA 301
           Q++K+FK  G+P+E+ W  + +LP    +   + PY                 L++  L 
Sbjct: 631 QINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLT 690

Query: 302 IDPDRRGTASAALNHEFFTTEPYACEPSSLPKYPPSKE 339
             P RR +A   L HE+F   P   +PS  P +P   E
Sbjct: 691 YFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSE 728


>CDK2_CARAU (P43450) Cell division protein kinase 2 (EC 2.7.1.37)
          Length = 298

 Score =  223 bits (567), Expect = 1e-57
 Identities = 128/293 (43%), Positives = 178/293 (60%), Gaps = 16/293 (5%)

Query: 34  SFEKLAKIGQGTYSNVYKAKDLVTGKIVALKKVRFDNLEPESVKFMA-REILVLRKLDHP 92
           SF+K+ KIG+GTY  VYKAK+ VTG+ VALKK+R D  E E V   A REI +L++L+HP
Sbjct: 3   SFQKVEKIGEGTYGVVYKAKNKVTGETVALKKIRLDT-ETEGVPSTAIREISLLKELNHP 61

Query: 93  NVVKLEGLVTSRMSCSLYLVFEYMEHDLAGLSAGQGVK-FTEPQVKCFMKQLLSGLEHCH 151
           N+VKL  ++ +     LYLVFE++  DL        V   + P VK ++ QLL GL  CH
Sbjct: 62  NIVKLHDVIHTENK--LYLVFEFLHQDLKRFMDSSTVTGISLPLVKSYLFQLLQGLAFCH 119

Query: 152 SRGVLHRDIKGSNLLIDNEGILKIADFGLATFYNPNKKQSMTSRVVTLWYRPPELLLGAT 211
           S  VLHRD+K  NLLI+ +G +K+ADFGLA  +    + + T  VVTLWYR PE+LLG  
Sbjct: 120 SHRVLHRDLKPQNLLINAQGEIKLADFGLARAFGVPVR-TYTHEVVTLWYRAPEILLGCK 178

Query: 212 FYGVGIDLWSAGCILAELLAGKPIMPGRTEVEQLHKIFKLCGSPAEEYWRKHKLPNATI- 270
           +Y   +D+WS GCI AE++  K + PG +E++QL +IF+  G+P E  W     P  T  
Sbjct: 179 YYSTAVDIWSLGCIFAEMITRKALFPGDSEIDQLFRIFRTLGTPDESIW-----PGVTSM 233

Query: 271 --FKPQQP--YKRCISETFKDFPPSSLPLIDSLLAIDPDRRGTASAALNHEFF 319
             +KP  P   ++ +S+           L+  +L  DP++R +A  AL H FF
Sbjct: 234 PDYKPSFPKWARQDLSKVVPPLDEDGRDLLGQMLIYDPNKRISAKNALVHRFF 286


>CDK2_CRIGR (O55076) Cell division protein kinase 2 (EC 2.7.1.37)
          Length = 298

 Score =  222 bits (565), Expect = 2e-57
 Identities = 131/296 (44%), Positives = 182/296 (61%), Gaps = 22/296 (7%)

Query: 34  SFEKLAKIGQGTYSNVYKAKDLVTGKIVALKKVRFDNLEPESVKFMA-REILVLRKLDHP 92
           +F+K+ KIG+GTY  VYKAK+ +TG++VALKK+R D  E E V   A REI +L++L+HP
Sbjct: 3   NFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDT-ETEGVPSTAIREISLLKELNHP 61

Query: 93  NVVKLEGLVTSRMSCSLYLVFEYMEHDLAGL---SAGQGVKFTEPQVKCFMKQLLSGLEH 149
           N+VKL  ++ +     LYLVFE++  DL      SA  G+    P +K ++ QLL GL  
Sbjct: 62  NIVKLLDVIHTENK--LYLVFEFLHQDLKKFMDASAVTGIPL--PLIKSYLFQLLQGLAF 117

Query: 150 CHSRGVLHRDIKGSNLLIDNEGILKIADFGLATFYNPNKKQSMTSRVVTLWYRPPELLLG 209
           CHS  VLHRD+K  NLLI+ EG +K+ADFGLA  +    + + T  VVTLWYR PE+LLG
Sbjct: 118 CHSHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVPVR-TYTHEVVTLWYRAPEILLG 176

Query: 210 ATFYGVGIDLWSAGCILAELLAGKPIMPGRTEVEQLHKIFKLCGSPAEEYWRKHKLPNAT 269
             +Y   +D+WS GCI AE++  + + PG +E++QL +IF+  G+P E  W     P  T
Sbjct: 177 CKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVW-----PGVT 231

Query: 270 I---FKPQQPYKRCISETFKDFPP---SSLPLIDSLLAIDPDRRGTASAALNHEFF 319
               +KP  P K    +  K  PP       L+  +L  DP++R +A AAL H FF
Sbjct: 232 SMPDYKPSFP-KWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFF 286


>CDK2_HUMAN (P24941) Cell division protein kinase 2 (EC 2.7.1.37)
           (p33 protein kinase)
          Length = 298

 Score =  221 bits (564), Expect = 3e-57
 Identities = 130/296 (43%), Positives = 182/296 (60%), Gaps = 22/296 (7%)

Query: 34  SFEKLAKIGQGTYSNVYKAKDLVTGKIVALKKVRFDNLEPESVKFMA-REILVLRKLDHP 92
           +F+K+ KIG+GTY  VYKA++ +TG++VALKK+R D  E E V   A REI +L++L+HP
Sbjct: 3   NFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDT-ETEGVPSTAIREISLLKELNHP 61

Query: 93  NVVKLEGLVTSRMSCSLYLVFEYMEHDLAGL---SAGQGVKFTEPQVKCFMKQLLSGLEH 149
           N+VKL  ++ +     LYLVFE++  DL      SA  G+    P +K ++ QLL GL  
Sbjct: 62  NIVKLLDVIHTENK--LYLVFEFLHQDLKKFMDASALTGIPL--PLIKSYLFQLLQGLAF 117

Query: 150 CHSRGVLHRDIKGSNLLIDNEGILKIADFGLATFYNPNKKQSMTSRVVTLWYRPPELLLG 209
           CHS  VLHRD+K  NLLI+ EG +K+ADFGLA  +    + + T  VVTLWYR PE+LLG
Sbjct: 118 CHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVR-TYTHEVVTLWYRAPEILLG 176

Query: 210 ATFYGVGIDLWSAGCILAELLAGKPIMPGRTEVEQLHKIFKLCGSPAEEYWRKHKLPNAT 269
             +Y   +D+WS GCI AE++  + + PG +E++QL +IF+  G+P E  W     P  T
Sbjct: 177 CKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVW-----PGVT 231

Query: 270 I---FKPQQPYKRCISETFKDFPP---SSLPLIDSLLAIDPDRRGTASAALNHEFF 319
               +KP  P K    +  K  PP       L+  +L  DP++R +A AAL H FF
Sbjct: 232 SMPDYKPSFP-KWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFF 286


>CDK2_RAT (Q63699) Cell division protein kinase 2 (EC 2.7.1.37)
          Length = 298

 Score =  221 bits (563), Expect = 3e-57
 Identities = 129/294 (43%), Positives = 180/294 (60%), Gaps = 18/294 (6%)

Query: 34  SFEKLAKIGQGTYSNVYKAKDLVTGKIVALKKVRFDNLEPESVKFMA-REILVLRKLDHP 92
           +F+K+ KIG+GTY  VYKAK+ +TG++VALKK+R D  E E V   A REI +L++L+HP
Sbjct: 3   NFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDT-ETEGVPSTAIREISLLKELNHP 61

Query: 93  NVVKLEGLVTSRMSCSLYLVFEYMEHDLAG-LSAGQGVKFTEPQVKCFMKQLLSGLEHCH 151
           N+VKL  ++ +     LYLVFE++  DL   + A        P +K ++ QLL GL  CH
Sbjct: 62  NIVKLLDVIHTENK--LYLVFEFLHQDLKKFMDASALTGLPLPLIKSYLFQLLQGLAFCH 119

Query: 152 SRGVLHRDIKGSNLLIDNEGILKIADFGLATFYNPNKKQSMTSRVVTLWYRPPELLLGAT 211
           S  VLHRD+K  NLLI+ EG +K+ADFGLA  +    + + T  VVTLWYR PE+LLG  
Sbjct: 120 SHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVPVR-TYTHEVVTLWYRAPEILLGCK 178

Query: 212 FYGVGIDLWSAGCILAELLAGKPIMPGRTEVEQLHKIFKLCGSPAEEYWRKHKLPNATI- 270
           +Y   +D+WS GCI AE++  + + PG +E++QL +IF+  G+P E  W     P  T  
Sbjct: 179 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVW-----PGVTSM 233

Query: 271 --FKPQQPYKRCISETFKDFPP---SSLPLIDSLLAIDPDRRGTASAALNHEFF 319
             +KP  P K    +  K  PP       L+  +L  DP++R +A AAL H FF
Sbjct: 234 PDYKPSFP-KWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFF 286


>CC2A_ARATH (P24100) Cell division control protein 2 homolog A (EC
           2.7.1.37)
          Length = 294

 Score =  221 bits (562), Expect = 4e-57
 Identities = 127/292 (43%), Positives = 183/292 (62%), Gaps = 11/292 (3%)

Query: 33  NSFEKLAKIGQGTYSNVYKAKDLVTGKIVALKKVRFDNLEPESVKFMA-REILVLRKLDH 91
           + +EK+ KIG+GTY  VYKA+D VT + +ALKK+R +  E E V   A REI +L+++ H
Sbjct: 2   DQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQ-EDEGVPSTAIREISLLKEMQH 60

Query: 92  PNVVKLEGLVTSRMSCSLYLVFEYMEHDLAG-LSAGQGVKFTEPQVKCFMKQLLSGLEHC 150
            N+VKL+ +V S     LYLVFEY++ DL   + +          +K ++ Q+L G+ +C
Sbjct: 61  SNIVKLQDVVHSEKR--LYLVFEYLDLDLKKHMDSTPDFSKDLHMIKTYLYQILRGIAYC 118

Query: 151 HSRGVLHRDIKGSNLLIDNE-GILKIADFGLATFYNPNKKQSMTSRVVTLWYRPPELLLG 209
           HS  VLHRD+K  NLLID     LK+ADFGLA  +    + + T  VVTLWYR PE+LLG
Sbjct: 119 HSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVR-TFTHEVVTLWYRAPEILLG 177

Query: 210 ATFYGVGIDLWSAGCILAELLAGKPIMPGRTEVEQLHKIFKLCGSPAEEYWR-KHKLPNA 268
           +  Y   +D+WS GCI AE+++ KP+ PG +E++QL KIF++ G+P E+ WR    LP+ 
Sbjct: 178 SHHYSTPVDIWSVGCIFAEMISQKPLFPGDSEIDQLFKIFRIMGTPYEDTWRGVTSLPDY 237

Query: 269 TIFKPQQPYKRCISETF-KDFPPSSLPLIDSLLAIDPDRRGTASAALNHEFF 319
               P+  +K    ETF  +  P  + L+  +L +DP +R  A AAL HE+F
Sbjct: 238 KSAFPK--WKPTDLETFVPNLDPDGVDLLSKMLLMDPTKRINARAALEHEYF 287


>CC2A_ANTMA (Q38772) Cell division control protein 2 homolog A (EC
           2.7.1.37)
          Length = 294

 Score =  221 bits (562), Expect = 4e-57
 Identities = 127/289 (43%), Positives = 181/289 (61%), Gaps = 9/289 (3%)

Query: 35  FEKLAKIGQGTYSNVYKAKDLVTGKIVALKKVRFDNLEPESVKFMA-REILVLRKLDHPN 93
           +EK+ KIG+GTY  VYKA+D VT + +ALKK+R +  E E V   A REI +L+++ H N
Sbjct: 4   YEKVEKIGEGTYGVVYKARDRVTNETIALKKIRLEQ-EDEGVPSTAIREISLLKEMQHGN 62

Query: 94  VVKLEGLVTSRMSCSLYLVFEYMEHDLAGLSAGQGVKFTEPQ-VKCFMKQLLSGLEHCHS 152
           +V+L+ +V S     LYLVFEY++ DL            +P+ VK F+ Q+L G+ +CHS
Sbjct: 63  IVRLQDVVHSEKR--LYLVFEYLDLDLKKHMDSCPEFSQDPRLVKMFLYQILRGIAYCHS 120

Query: 153 RGVLHRDIKGSNLLIDNE-GILKIADFGLATFYNPNKKQSMTSRVVTLWYRPPELLLGAT 211
             VLHRD+K  NLLID     LK+ADFGLA  +    + + T  VVTLWYR PE+LLG+ 
Sbjct: 121 HRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIPVR-TFTHEVVTLWYRAPEILLGSR 179

Query: 212 FYGVGIDLWSAGCILAELLAGKPIMPGRTEVEQLHKIFKLCGSPAEEYW-RKHKLPNATI 270
            Y   +D+WS GCI AE++  +P+ PG +E+++L KIF++ G+P EE W     LP+   
Sbjct: 180 HYSTPVDVWSVGCIFAEMVNQRPLFPGDSEIDELFKIFRVMGTPNEETWPGVTSLPDFKS 239

Query: 271 FKPQQPYKRCISETFKDFPPSSLPLIDSLLAIDPDRRGTASAALNHEFF 319
             P+ P K  ++    +   S L L+D +L +DP +R TA  AL HE+F
Sbjct: 240 AFPKWPAKE-LAAVVPNLDASGLDLLDKMLRLDPSKRITARNALQHEYF 287


>CC28_CANAL (P43063) Cell division control protein 28 (EC 2.7.1.37)
          Length = 317

 Score =  221 bits (562), Expect = 4e-57
 Identities = 126/292 (43%), Positives = 181/292 (61%), Gaps = 9/292 (3%)

Query: 33  NSFEKLAKIGQGTYSNVYKAKDLV-TGKIVALKKVRFDNLEPESVKFMA-REILVLRKLD 90
           + +++  K+G+GTY  VYKA D     ++VALKK+R ++ E E V   A REI +L+++ 
Sbjct: 5   SDYQRQEKVGEGTYGVVYKALDTKHNNRVVALKKIRLES-EDEGVPSTAIREISLLKEMK 63

Query: 91  HPNVVKLEGLVTSRMSCSLYLVFEYMEHDLAGL--SAGQGVKFTEPQVKCFMKQLLSGLE 148
             N+V+L  ++ S  S  LYLVFE+++ DL     S  QGV      +K FM QL+ G++
Sbjct: 64  DDNIVRLYDIIHSD-SHKLYLVFEFLDLDLKKYMESIPQGVGLGANMIKRFMNQLIRGIK 122

Query: 149 HCHSRGVLHRDIKGSNLLIDNEGILKIADFGLATFYNPNKKQSMTSRVVTLWYRPPELLL 208
           HCHS  VLHRD+K  NLLID EG LK+ADFGLA  +    + + T  VVTLWYR PE+LL
Sbjct: 123 HCHSHRVLHRDLKPQNLLIDKEGNLKLADFGLARAFGVPLR-AYTHEVVTLWYRAPEILL 181

Query: 209 GATFYGVGIDLWSAGCILAELLAGKPIMPGRTEVEQLHKIFKLCGSPAEEYWRK-HKLPN 267
           G   Y  G+D+WS GCI AE+   KP+ PG +E++++ +IF++ G+P EE W   + LP+
Sbjct: 182 GGKQYSTGVDMWSVGCIFAEMCNRKPLFPGDSEIDEIFRIFRILGTPNEEIWPDVNYLPD 241

Query: 268 ATIFKPQQPYKRCISETFKDFPPSSLPLIDSLLAIDPDRRGTASAALNHEFF 319
                PQ   K+ +SE       + + L+D +L  DP RR +A  AL H +F
Sbjct: 242 FKSSFPQWK-KKPLSEAVPSLDANGIDLLDQMLVYDPSRRISAKRALIHPYF 292


>CC22_MEDSA (Q05006) Cell division control protein 2 homolog 2 (EC
           2.7.1.37)
          Length = 294

 Score =  221 bits (562), Expect = 4e-57
 Identities = 124/289 (42%), Positives = 181/289 (61%), Gaps = 9/289 (3%)

Query: 35  FEKLAKIGQGTYSNVYKAKDLVTGKIVALKKVRFDNLEPESVKFMA-REILVLRKLDHPN 93
           +EK+ KIG+GTY  VYKA+D  T + +ALKK+R +  E E V   A REI +L+++ H N
Sbjct: 4   YEKVEKIGEGTYGVVYKARDRATNETIALKKIRLEQ-EDEGVPSTAIREISLLKEMQHRN 62

Query: 94  VVKLEGLVTSRMSCSLYLVFEYMEHDLAG-LSAGQGVKFTEPQVKCFMKQLLSGLEHCHS 152
           +V+L+ +V S     LYLVFEY++ DL   + +       + Q+K F+ Q+L G+ +CHS
Sbjct: 63  IVRLQDVVHSEKR--LYLVFEYLDLDLKKFMDSSPEFAKDQRQIKMFLYQILCGIAYCHS 120

Query: 153 RGVLHRDIKGSNLLID-NEGILKIADFGLATFYNPNKKQSMTSRVVTLWYRPPELLLGAT 211
             VLHRD+K  NLLID +   +K+ADFGLA  +    + + T  VVTLWYR PE+LLG+ 
Sbjct: 121 HRVLHRDLKPQNLLIDRSSNAVKLADFGLARAFGIPVR-TFTHEVVTLWYRAPEILLGSR 179

Query: 212 FYGVGIDLWSAGCILAELLAGKPIMPGRTEVEQLHKIFKLCGSPAEEYW-RKHKLPNATI 270
            Y   +D+WS GCI AE++  +P+ PG +E+++L KIF++ G+P EE W     LP+   
Sbjct: 180 HYSTPVDVWSVGCIFAEMINQRPLFPGDSEIDELFKIFRITGTPNEETWPGVTSLPDFKS 239

Query: 271 FKPQQPYKRCISETFKDFPPSSLPLIDSLLAIDPDRRGTASAALNHEFF 319
             P+ P K   ++   +  P+ L L+ S   +DP RR TA  AL HE+F
Sbjct: 240 AFPKWPAKDLATQV-PNLEPAGLDLLSSTCRLDPTRRITARGALEHEYF 287


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.317    0.134    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,360,427
Number of Sequences: 164201
Number of extensions: 2777131
Number of successful extensions: 11172
Number of sequences better than 10.0: 1687
Number of HSP's better than 10.0 without gapping: 1551
Number of HSP's successfully gapped in prelim test: 136
Number of HSP's that attempted gapping in prelim test: 6466
Number of HSP's gapped (non-prelim): 2000
length of query: 498
length of database: 59,974,054
effective HSP length: 114
effective length of query: 384
effective length of database: 41,255,140
effective search space: 15841973760
effective search space used: 15841973760
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)