BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC146743.7 + phase: 0
(376 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AK1H_SERMA (P27725) Bifunctional aspartokinase/homoserine dehydr... 200 4e-51
AK1H_ECOLI (P00561) Bifunctional aspartokinase/homoserine dehydr... 198 2e-50
AKH_HAEIN (P44505) Bifunctional aspartokinase/homoserine dehydro... 196 1e-49
AKH_BUCAI (P57290) Bifunctional aspartokinase/homoserine dehydro... 187 5e-47
AKH_BUCAP (Q8K9U9) Bifunctional aspartokinase/homoserine dehydro... 186 8e-47
AKH_BUCBP (Q89AR4) Bifunctional aspartokinase/homoserine dehydro... 183 5e-46
AKH2_MAIZE (P49080) Bifunctional aspartokinase/homoserine dehydr... 178 2e-44
AKH1_MAIZE (P49079) Bifunctional aspartokinase/homoserine dehydr... 178 2e-44
DHOM_YEAST (P31116) Homoserine dehydrogenase (EC 1.1.1.3) (HDH) 175 2e-43
AKH_DAUCA (P37142) Bifunctional aspartokinase/homoserine dehydro... 174 3e-43
DHOM_SCHPO (O94671) Probable homoserine dehydrogenase (EC 1.1.1.... 150 7e-36
AK2H_ECOLI (P00562) Bifunctional aspartokinase/homoserine dehydr... 145 1e-34
DHOM_BACSU (P19582) Homoserine dehydrogenase (EC 1.1.1.3) (HDH) 81 4e-15
DHOM_LACLC (P52985) Homoserine dehydrogenase (EC 1.1.1.3) (HDH) 81 5e-15
DHOM_LACLA (Q9CGD8) Homoserine dehydrogenase (EC 1.1.1.3) (HDH) 75 2e-13
DHOM_MYCLE (P46806) Homoserine dehydrogenase (EC 1.1.1.3) (HDH) 75 3e-13
DHOM_MYCTU (P63629) Homoserine dehydrogenase (EC 1.1.1.3) (HDH) 74 6e-13
DHOM_MYCBO (P63630) Homoserine dehydrogenase (EC 1.1.1.3) (HDH) 74 6e-13
DHOM_METJA (Q58997) Homoserine dehydrogenase (EC 1.1.1.3) (HDH) 74 6e-13
DHOM_PSEAE (P29365) Homoserine dehydrogenase (EC 1.1.1.3) (HDH) 73 1e-12
>AK1H_SERMA (P27725) Bifunctional aspartokinase/homoserine
dehydrogenase I (AKI-HDI) [Includes: Aspartokinase I (EC
2.7.2.4); Homoserine dehydrogenase I (EC 1.1.1.3)]
Length = 819
Score = 200 bits (509), Expect = 4e-51
Identities = 133/375 (35%), Positives = 198/375 (52%), Gaps = 35/375 (9%)
Query: 2 KTIPLILMGCGGVGSHLLQHIVSSRSLHSSQGLCLRVVGIGDSKSLVVVDDLLNKGFDDS 61
+ I + ++G GGVG L++ I + + + LRV GI +S+ ++
Sbjct: 464 QVIEVFVIGVGGVGGALIEQIYRQQPWLKQKHIDLRVCGIANSRVMLTN----------- 512
Query: 62 FLLELCRLKHGGESLSKLGDLGQCQVFVHPESEGKILEIASQLGKKTGLAFVDCTASSDT 121
HG S L Q P + G+++ + + + VDCT+S
Sbjct: 513 --------VHGIALDSWRDALAGAQ---EPFNLGRLIRLVKEYHLLNPV-IVDCTSSQ-- 558
Query: 122 IVVLKQVVDL---GCCVVMANKKPLTSTMGDFEKLLTYP----RRIRHESTVGAGLPVIS 174
V Q VD G VV NKK TS+M +++L R+ +++ VGAGLPVI
Sbjct: 559 -AVADQYVDFLADGFHVVTPNKKANTSSMNYYQQLRAAAAGSHRKFLYDTNVGAGLPVIE 617
Query: 175 SLNRIISSGDPVNRIIGSLSGTLGYVMSEVEDGKPLSQVVRAAKSLGYTEPDPRDDLGGM 234
+L ++++GD + R G LSG+L ++ ++++G LS A++ GYTEPDPRDDL GM
Sbjct: 618 NLQNLLNAGDELVRFSGILSGSLSFIFGKLDEGLSLSAATLQARANGYTEPDPRDDLSGM 677
Query: 235 DVARKALILARILGRRINMDSIQIESLYPKEMGPDVMTDDDFLSCGLLLLDKDIQERVEK 294
DVARK LILAR G ++ + I++E + P D D D L LDK+ V
Sbjct: 678 DVARKLLILAREAGYKLELSDIEVEPVLPPSF--DASGDVDTFLARLPELDKEFARNVAN 735
Query: 295 AASNGNVLRYVCVIEGPRCEVGIQELPKNSALGRLRGSDNVLEVYTRCYSNQPLVIQGAG 354
AA G VLRYV +I+ RC+V I+ + N L +++ +N L Y+R Y PLV++G G
Sbjct: 736 AAEQGKVLRYVGLIDEGRCKVRIEAVDGNDPLYKVKNGENALAFYSRYYQPLPLVLRGYG 795
Query: 355 AGNDTTAAGVLADIV 369
AGND TAAGV AD++
Sbjct: 796 AGNDVTAAGVFADLL 810
>AK1H_ECOLI (P00561) Bifunctional aspartokinase/homoserine
dehydrogenase I (AKI-HDI) [Includes: Aspartokinase I (EC
2.7.2.4); Homoserine dehydrogenase I (EC 1.1.1.3)]
Length = 820
Score = 198 bits (504), Expect = 2e-50
Identities = 133/374 (35%), Positives = 198/374 (52%), Gaps = 32/374 (8%)
Query: 2 KTIPLILMGCGGVGSHLLQHIVSSRSLHSSQGLCLRVVGIGDSKSLVVVDDLLNKGFDDS 61
+ I + ++G GGVG LL+ + +S ++ + LRV G+ +SK+L+ LN
Sbjct: 464 QVIEVFVIGVGGVGGALLEQLKRQQSWLKNKHIDLRVCGVANSKALLTNVHGLN------ 517
Query: 62 FLLELCRLKHGGESLSKLGDLGQCQVFVHPESEGKILEIASQLGKKTGLAFVDCTASSDT 121
L++ E L++ + P + G+++ + + + VDCT+S
Sbjct: 518 -------LENWQEELAQAKE---------PFNLGRLIRLVKEYHLLNPV-IVDCTSSQAV 560
Query: 122 IVVLKQVVDLGCCVVMANKKPLTSTMGDFEKLLTYP-----RRIRHESTVGAGLPVISSL 176
+ G VV NKK TS+M D+ L Y R+ +++ VGAGLPVI +L
Sbjct: 561 ADQYADFLREGFHVVTPNKKANTSSM-DYYHQLRYAAEKSRRKFLYDTNVGAGLPVIENL 619
Query: 177 NRIISSGDPVNRIIGSLSGTLGYVMSEVEDGKPLSQVVRAAKSLGYTEPDPRDDLGGMDV 236
++++GD + + G LSG+L Y+ ++++G S+ A+ +GYTEPDPRDDL GMDV
Sbjct: 620 QNLLNAGDELMKFSGILSGSLSYIFGKLDEGMSFSEATTLAREMGYTEPDPRDDLSGMDV 679
Query: 237 ARKALILARILGRRINMDSIQIESLYPKEMGPDVMTDDDFLSCGLLLLDKDIQERVEKAA 296
ARK LILAR GR + + I+IE + P E + D L LD RV KA
Sbjct: 680 ARKLLILARETGRELELADIEIEPVLPAEFNAE--GDVAAFMANLSQLDDLFAARVAKAR 737
Query: 297 SNGNVLRYVCVI-EGPRCEVGIQELPKNSALGRLRGSDNVLEVYTRCYSNQPLVIQGAGA 355
G VLRYV I E C V I E+ N L +++ +N L Y+ Y PLV++G GA
Sbjct: 738 DEGKVLRYVGNIDEDGVCRVKIAEVDGNDPLFKVKNGENALAFYSHYYQPLPLVLRGYGA 797
Query: 356 GNDTTAAGVLADIV 369
GND TAAGV AD++
Sbjct: 798 GNDVTAAGVFADLL 811
>AKH_HAEIN (P44505) Bifunctional aspartokinase/homoserine
dehydrogenase (AK-HD) [Includes: Aspartokinase (EC
2.7.2.4); Homoserine dehydrogenase (EC 1.1.1.3)]
Length = 815
Score = 196 bits (497), Expect = 1e-49
Identities = 123/372 (33%), Positives = 199/372 (53%), Gaps = 29/372 (7%)
Query: 2 KTIPLILMGCGGVGSHLLQHIVSSRSLHSSQGLCLRVVGIGDSKSLVVVDDLLNKGFDDS 61
K + + L+G GGVG L++ + + + + + +RV I +S +++ ++ LN
Sbjct: 464 KVVDMFLVGVGGVGGELIEQVKRQKEYLAKKNVEIRVCAIANSNRMLLDENGLN------ 517
Query: 62 FLLELCRLKHGGESLSKLGDLGQCQVFVHPESEGKILEIASQLGKKTGLAFVDCTASSDT 121
L K+ E+ ++ D F+ +L FVDCT++
Sbjct: 518 ----LEDWKNDLENATQPSDFDVLLSFI-------------KLHHVVNPVFVDCTSAESV 560
Query: 122 IVVLKQVVDLGCCVVMANKKPLTSTMGDFEKLLTYPRRIRH----ESTVGAGLPVISSLN 177
+ + + G VV NKK T + + +L + +H E+ VGAGLPVI +L
Sbjct: 561 AGLYARALKEGFHVVTPNKKANTRELVYYNELRQNAQASQHKFLYETNVGAGLPVIENLQ 620
Query: 178 RIISSGDPVNRIIGSLSGTLGYVMSEVEDGKPLSQVVRAAKSLGYTEPDPRDDLGGMDVA 237
++++GD + G LSG+L ++ ++E+G LS+V A+ G+TEPDPRDDL G DVA
Sbjct: 621 NLLAAGDELEYFEGILSGSLSFIFGKLEEGLSLSEVTALAREKGFTEPDPRDDLSGQDVA 680
Query: 238 RKALILARILGRRINMDSIQIESLYPKEMGPDVMTDDDFLSCGLLLLDKDIQERVEKAAS 297
RK LILAR G + + +++E + PK D + D+F++ L LD++ + RV A +
Sbjct: 681 RKLLILAREAGIELELSDVEVEGVLPKGFS-DGKSADEFMAM-LPQLDEEFKTRVATAKA 738
Query: 298 NGNVLRYVCVIEGPRCEVGIQELPKNSALGRLRGSDNVLEVYTRCYSNQPLVIQGAGAGN 357
G VLRYV I +C+V I + N+ L +++ +N L YTR Y PL+++G GAGN
Sbjct: 739 EGKVLRYVGKISEGKCKVSIVAVDLNNPLYKVKDGENALAFYTRYYQPIPLLLRGYGAGN 798
Query: 358 DTTAAGVLADIV 369
TAAG+ ADI+
Sbjct: 799 AVTAAGIFADIL 810
>AKH_BUCAI (P57290) Bifunctional aspartokinase/homoserine
dehydrogenase (AK-HD) [Includes: Aspartokinase (EC
2.7.2.4); Homoserine dehydrogenase (EC 1.1.1.3)]
Length = 816
Score = 187 bits (474), Expect = 5e-47
Identities = 125/376 (33%), Positives = 193/376 (51%), Gaps = 36/376 (9%)
Query: 2 KTIPLILMGCGGVGSHLLQHIVSSRSLHSSQGLCLRVVGIGDSKSLVVVDDLLNKGFDDS 61
KTI + L+G GG+GS LL I+ + + + +++ I +SK ++++D+
Sbjct: 465 KTIHMFLIGIGGIGSTLLNQILKQKQFLDKKNIEIKICAIANSKKILLLDNT-------- 516
Query: 62 FLLELCRLKHGGESLSKLGDLGQCQVFVHPESEGKILEIASQLGKKTGLA---FVDCTAS 118
DL + ++ LE+ + L K + VDCT+S
Sbjct: 517 ------------------NDLSNWKNDFKKSTQKFNLELLNNLIKNNHFSNSVIVDCTSS 558
Query: 119 SDTIVVLKQVVDLGCCVVMANKKPLTSTMGDFEKL----LTYPRRIRHESTVGAGLPVIS 174
+D VV +NKK TS ++K+ ++ +E+ VGAGLPVI
Sbjct: 559 QLLSEQYVNFIDNNFHVVTSNKKANTSEWNYYKKIRKSVAQTGKKFLYETNVGAGLPVIE 618
Query: 175 SLNRIISSGDPVNRIIGSLSGTLGYVMSEVEDGKPLSQVVRAAKSLGYTEPDPRDDLGGM 234
+L + SGD + G LSG+L ++ +E+G LSQ R AK LG+TEP+P DDL G+
Sbjct: 619 TLQNLFKSGDNLICFKGILSGSLSFIFGRLEEGILLSQATREAKELGFTEPNPCDDLSGI 678
Query: 235 DVARKALILARILGRRINMDSIQIESLYPKEMGPDVMTDDDFLSCGLLLLDKDIQERVEK 294
DVARK LILAR G I + I+IE L P + D D L LD ++++
Sbjct: 679 DVARKLLILARESGYNIELKDIKIEPLLPNNF--KIYEDTDKFLLKLKELDVYFSNKIKQ 736
Query: 295 AASNGNVLRYVCVIEGPR-CEVGIQELPKNSALGRLRGSDNVLEVYTRCYSNQPLVIQGA 353
A + GNVLR+V IE R + ++E+ N+ L +++ +N L YT Y PLV++G
Sbjct: 737 ALNVGNVLRFVATIEQKRQFFIKLEEVNINNPLYKVKNGENALAFYTNYYQPIPLVLRGY 796
Query: 354 GAGNDTTAAGVLADIV 369
GAGN+ TA+GV +D++
Sbjct: 797 GAGNNVTASGVFSDLL 812
>AKH_BUCAP (Q8K9U9) Bifunctional aspartokinase/homoserine
dehydrogenase (AK-HD) [Includes: Aspartokinase (EC
2.7.2.4); Homoserine dehydrogenase (EC 1.1.1.3)]
Length = 814
Score = 186 bits (472), Expect = 8e-47
Identities = 128/379 (33%), Positives = 200/379 (51%), Gaps = 42/379 (11%)
Query: 4 IPLILMGCGGVGSHLLQHIVSSRSLHSSQGLCLRVVGIGDSKSLVVVDDLLNKGFDDSFL 63
I + L+G GGVG LL+ I+ + + ++ I +SK L+ + + +N
Sbjct: 465 INVFLIGIGGVGKALLKQILKQEKFLDQKNIKIQFRMIANSKKLLFLKNSIN-------- 516
Query: 64 LELCRLKHGGESLSKLGDLGQCQVFVHPESEGKILEIASQLGKKT---GLAFVDCTASSD 120
L + E+ K E L I ++L K T +DCT+
Sbjct: 517 -----LNNWEENFKK-------------SKEKFNLTILNELLKNTCDSNSVIIDCTSD-- 556
Query: 121 TIVVLKQVVDL---GCCVVMANKKPLTSTMGDFEKLLTYP----RRIRHESTVGAGLPVI 173
++ KQ + G ++ +NKK T ++ + ++ T ++ +E+ VGAGLPVI
Sbjct: 557 -YILSKQYISFIKKGFHIITSNKKANTDSLKYYSEIRTTALKENKKFLYETNVGAGLPVI 615
Query: 174 SSLNRIISSGDPVNRIIGSLSGTLGYVMSEVEDGKPLSQVVRAAKSLGYTEPDPRDDLGG 233
++L + S+GD + G LSG+L ++ ++E+G LS+ + AK LG+TEP+P DDL G
Sbjct: 616 NTLQSLFSTGDCLISFKGILSGSLSFIFGKLEEGVLLSEATKEAKKLGFTEPNPFDDLSG 675
Query: 234 MDVARKALILARILGRRINMDSIQIESLYPKEMGPDVMTDDDFLSCGLLLLDKDIQERVE 293
+DVARK L+LAR +G I + I IE + P E ++FL L LD ERV
Sbjct: 676 IDVARKLLVLAREIGYSIELKDISIEPILP-ERFKKYQNSEEFL-FKLKELDSFFSERVN 733
Query: 294 KAASNGNVLRYVCVIE-GPRCEVGIQELPKNSALGRLRGSDNVLEVYTRCYSNQPLVIQG 352
KA GNVLR++ IE +C V I+E+ N+ L +++ +N L YT Y PLV++G
Sbjct: 734 KARDIGNVLRFIGSIEKNGKCSVKIEEINSNNPLYKVKNGENALTFYTNYYQPIPLVLRG 793
Query: 353 AGAGNDTTAAGVLADIVDI 371
GAGND TA+GV +D++ I
Sbjct: 794 YGAGNDVTASGVFSDLLRI 812
>AKH_BUCBP (Q89AR4) Bifunctional aspartokinase/homoserine
dehydrogenase (AK-HD) [Includes: Aspartokinase (EC
2.7.2.4); Homoserine dehydrogenase (EC 1.1.1.3)]
Length = 816
Score = 183 bits (465), Expect = 5e-46
Identities = 122/377 (32%), Positives = 202/377 (53%), Gaps = 36/377 (9%)
Query: 3 TIPLILMGCGGVGSHLLQHIVSSRSLHSSQGLCLRVVGIGDSKSLVVVDDLLN-KGF--D 59
T + L+G G VG L+ I+ ++ S+ + L++ GI +SK+ ++ D +N K + D
Sbjct: 466 TAEIFLIGIGRVGQTFLKQIIEQKNWLKSKNIDLKICGIANSKNFILNLDGINPKNWKRD 525
Query: 60 DSFLLELCRLKHGGESLSKLGDLGQCQVFVHPESEGKILEIASQLGKKTGLAFVDCTASS 119
+ + KH S+ Q ++P VDCT+
Sbjct: 526 LNLSKKSFNFKHLLNSI-------QNYYLINP-------------------IIVDCTSDK 559
Query: 120 DTIVVLKQVVDLGCCVVMANKKPLTSTMGDFEKLLTYPRRIR----HESTVGAGLPVISS 175
+ ++ G +V NKK T+ +E + ++ + +E+ VGAGLPVI +
Sbjct: 560 NIANQYISFINCGFHIVTPNKKANTTNWKYYEDIRLAAQKEKKKFFYETNVGAGLPVIEN 619
Query: 176 LNRIISSGDPVNRIIGSLSGTLGYVMSEVEDGKPLSQVVRAAKSLGYTEPDPRDDLGGMD 235
L ++ +GD + G LSG+L ++ ++ED LS+ + A+SLG+TEP+P+DDL G+D
Sbjct: 620 LKNLLRTGDTLIHFKGILSGSLSFIFGKLEDNISLSEATKQAQSLGFTEPNPKDDLSGID 679
Query: 236 VARKALILARILGRRINMDSIQIESLYPKEMGPDVMTDDDFLSCGLLLLDKDIQERVEKA 295
VARK LILAR +G ++ + I+IE L PKE ++ DF++ L LD+ RV+KA
Sbjct: 680 VARKLLILAREVGYKLELKDIKIEPLLPKEFN-NISNTTDFIT-KLKELDQIFCNRVKKA 737
Query: 296 ASNGNVLRYVCVI-EGPRCEVGIQELPKNSALGRLRGSDNVLEVYTRCYSNQPLVIQGAG 354
G LR+V +I + C+V I E+ N L ++ +N L Y++ Y PLV++G G
Sbjct: 738 RKLGKRLRFVGIINQKGNCQVKIDEVDHNDPLYNIKNGENALAFYSKYYQPIPLVLRGYG 797
Query: 355 AGNDTTAAGVLADIVDI 371
AGN+ TA+G+ +D++ I
Sbjct: 798 AGNNVTASGIFSDVLRI 814
>AKH2_MAIZE (P49080) Bifunctional aspartokinase/homoserine
dehydrogenase 2, chloroplast precursor (AK-HD 2)
(AK-HSDH 2) [Includes: Aspartokinase (EC 2.7.2.4);
Homoserine dehydrogenase (EC 1.1.1.3)]
Length = 917
Score = 178 bits (452), Expect = 2e-44
Identities = 123/374 (32%), Positives = 192/374 (50%), Gaps = 31/374 (8%)
Query: 3 TIPLILMGCGGVGSHLLQHIVSSRS-LHSSQGLCLRVVGIGDSKSLVVVDDLLNKGFDDS 61
T+ + ++G G +G LL + + + L + + LRV+GI S ++++ D G D
Sbjct: 558 TLAVGIIGPGLIGGALLNQLKNQTAVLKENMNIDLRVIGITGSSTMLLSDT----GID-- 611
Query: 62 FLLELCRLKHGGESLSKLGDLGQCQVFVHPESEGKILEIASQLGKKTGLAFVDCTASSDT 121
L + K + ++ D+G FVH S+ + VDCTA +
Sbjct: 612 ----LTQWKQLLQKEAEPADIGS---FVHHLSDNHVFP---------NKVLVDCTADTSV 655
Query: 122 IVVLKQVVDLGCCVVMANKKPLTSTMGDFEKLLTYPR----RIRHESTVGAGLPVISSLN 177
+ G V+ NKK + + + KL T R +E+TVGAGLP+IS+L
Sbjct: 656 ASHYYDWLKKGIHVITPNKKANSGPLDQYLKLRTMQRASYTHYFYEATVGAGLPIISTLR 715
Query: 178 RIISSGDPVNRIIGSLSGTLGYVMSEVEDGKPLSQVVRAAKSLGYTEPDPRDDLGGMDVA 237
++ +GD + RI G SGTL Y+ + E + S VV A+ GYTEPDPRDDL G DVA
Sbjct: 716 GLLETGDKILRIEGIFSGTLSYIFNNFEGTRAFSDVVAEAREAGYTEPDPRDDLSGTDVA 775
Query: 238 RKALILARILGRRINMDSIQIESLYPKEMGPDVMTDDDFLSCGLLLLDKDIQERVEKAAS 297
RK ++LAR G R+ + I ++SL P+ + + D+F+ L D+D + A +
Sbjct: 776 RKVVVLARESGLRLELSDIPVKSLVPETLA-SCSSADEFMQ-KLPSFDEDWARQRSDAEA 833
Query: 298 NGNVLRYVCVIEGPR--CEVGIQELPKNSALGRLRGSDNVLEVYTRCYSNQPLVIQGAGA 355
G VLRYV ++ +V ++ ++ +L GSDN++ T Y QPL+++G GA
Sbjct: 834 AGEVLRYVGALDAVNRSGQVELRRYRRDHPFAQLSGSDNIIAFTTSRYKEQPLIVRGPGA 893
Query: 356 GNDTTAAGVLADIV 369
G + TA GV DI+
Sbjct: 894 GAEVTAGGVFCDIL 907
>AKH1_MAIZE (P49079) Bifunctional aspartokinase/homoserine
dehydrogenase 1, chloroplast precursor (AK-HD 1)
(AK-HSDH 1) [Includes: Aspartokinase (EC 2.7.2.4);
Homoserine dehydrogenase (EC 1.1.1.3)]
Length = 920
Score = 178 bits (452), Expect = 2e-44
Identities = 124/374 (33%), Positives = 187/374 (49%), Gaps = 31/374 (8%)
Query: 3 TIPLILMGCGGVGSHLLQHIVSSRS-LHSSQGLCLRVVGIGDSKSLVVVDDLLNKGFDDS 61
T+ + ++G G +G LL + + L + + LRV+GI S+++++ D G D
Sbjct: 561 TLAVGIIGPGLIGRTLLNQLKDQAAVLKENMNIDLRVMGIAGSRTMLLSDI----GVD-- 614
Query: 62 FLLELCRLKHGGESLSKLGDLGQCQVFVHPESEGKILEIASQLGKKTGLAFVDCTASSDT 121
L E L + FVH SE VDCTA +
Sbjct: 615 -------LTQWKEKLQTEAEPANLDKFVHHLSENHFFP---------NRVLVDCTADTSV 658
Query: 122 IVVLKQVVDLGCCVVMANKKPLTSTMGDFEKLLTYPR----RIRHESTVGAGLPVISSLN 177
+ G V+ NKK + + + KL T R +E+TVGAGLP+IS+L
Sbjct: 659 ASHYYDWLKKGIHVITPNKKANSGPLDRYLKLRTLQRASYTHYFYEATVGAGLPIISTLR 718
Query: 178 RIISSGDPVNRIIGSLSGTLGYVMSEVEDGKPLSQVVRAAKSLGYTEPDPRDDLGGMDVA 237
++ +GD + RI G SGTL Y+ + E + S VV AK GYTEPDPRDDL G DVA
Sbjct: 719 GLLETGDKILRIEGIFSGTLSYIFNNFEGARTFSDVVAEAKKAGYTEPDPRDDLSGTDVA 778
Query: 238 RKALILARILGRRINMDSIQIESLYPKEMGPDVMTDDDFLSCGLLLLDKDIQERVEKAAS 297
RK +ILAR G + + I + SL P+ + + D+++ L D+D + A +
Sbjct: 779 RKVIILARESGLGLELSDIPVRSLVPEAL-KSCTSADEYMQ-KLPSFDEDWARERKNAEA 836
Query: 298 NGNVLRYVCVIE--GPRCEVGIQELPKNSALGRLRGSDNVLEVYTRCYSNQPLVIQGAGA 355
G VLRYV V++ + +V ++ ++ +L GSDN++ T Y +QPL+++G GA
Sbjct: 837 AGEVLRYVGVVDVVSKKGQVELRAYKRDHPFAQLSGSDNIIAFTTSRYKDQPLIVRGPGA 896
Query: 356 GNDTTAAGVLADIV 369
G + TA GV DI+
Sbjct: 897 GAEVTAGGVFCDIL 910
>DHOM_YEAST (P31116) Homoserine dehydrogenase (EC 1.1.1.3) (HDH)
Length = 359
Score = 175 bits (443), Expect = 2e-43
Identities = 110/269 (40%), Positives = 158/269 (57%), Gaps = 13/269 (4%)
Query: 113 VDCTASSDTIVVLKQVVDLGCCVVMANKKPLTSTMGDFEKLLTYPRR---IRHESTVGAG 169
VD T+S+ + V+ G + NKK +S + ++ L + + HE+TVGAG
Sbjct: 90 VDNTSSAYIAGFYTKFVENGISIATPNKKAFSSDLATWKALFSNKPTNGFVYHEATVGAG 149
Query: 170 LPVISSLNRIISSGDPVNRIIGSLSGTLGYVMSEVEDGKP----LSQVVRAAKSLGYTEP 225
LP+IS L II +GD V +I G SGTL Y+ +E + S VV+ AK LGYTEP
Sbjct: 150 LPIISFLREIIQTGDEVEKIEGIFSGTLSYIFNEFSTSQANDVKFSDVVKVAKKLGYTEP 209
Query: 226 DPRDDLGGMDVARKALILARILGRRI-NMDSIQIESLYPKEMGPDVMTDDDFLSCGLLLL 284
DPRDDL G+DVARK I+ RI G + + S ++SL PK + V + D+FL L
Sbjct: 210 DPRDDLNGLDVARKVTIVGRISGVEVESPTSFPVQSLIPKPL-ESVKSADEFLE-KLSDY 267
Query: 285 DKDIQERVEKAASNGNVLRYVCVIE--GPRCEVGIQELPKNSALGRLRGSDNVLEVYTRC 342
DKD+ + ++AA+ VLR++ ++ VGI++ + L+GSDNV+ + T+
Sbjct: 268 DKDLTQLKKEAATENKVLRFIGKVDVATKSVSVGIEKYDYSHPFASLKGSDNVISIKTKR 327
Query: 343 YSNQPLVIQGAGAGNDTTAAGVLADIVDI 371
Y+N P+VIQGAGAG TAAGVL D++ I
Sbjct: 328 YTN-PVVIQGAGAGAAVTAAGVLGDVIKI 355
>AKH_DAUCA (P37142) Bifunctional aspartokinase/homoserine
dehydrogenase, chloroplast precursor (AK-HD) (AK-HSDH)
[Includes: Aspartokinase (EC 2.7.2.4); Homoserine
dehydrogenase (EC 1.1.1.3)] (Fragment)
Length = 921
Score = 174 bits (442), Expect = 3e-43
Identities = 127/375 (33%), Positives = 192/375 (50%), Gaps = 33/375 (8%)
Query: 3 TIPLILMGCGGVGSHLLQHIVSSRS-LHSSQGLCLRVVGIGDSKSLVVVDDLLNKGFDDS 61
TI + ++G G +G+ LL + + L + + LRV+GI S++++ L G D S
Sbjct: 562 TIAVGIVGPGLIGATLLDQLRDQAAILKENSKIDLRVMGITGSRTML----LSETGIDLS 617
Query: 62 FLLELCRLKHGGESLSKLGDLGQCQVFVHPESEGKILEIASQLGKKTGLAFVDCTASSDT 121
E+ + K L K + F+ VDCTA S+
Sbjct: 618 RWREVQKEKGQTAGLEKFVQHVRGNHFI------------------PSTVIVDCTADSEV 659
Query: 122 IVVLKQVVDLGCCVVMANKKPLTSTMGDFEKLLTYPRRIR----HESTVGAGLPVISSLN 177
+ G V+ NKK + + + KL RR +E+TV AGLP+I++L
Sbjct: 660 ASHYHDWLCRGIHVITPNKKANSGPLDQYLKLRALQRRSYTHYFYEATVVAGLPIITTLQ 719
Query: 178 RIISSGDPVNRIIGSLSGTLGYVMSEVEDGKPLSQVVRAAKSLGYTEPDPRDDLGGMDVA 237
++ +GD + RI G SGTL Y+ + + P S+VV AK+ GYTEPDPRDDL G DVA
Sbjct: 720 GLLETGDKILRIEGIFSGTLSYIFNNFKSTTPFSEVVSEAKAAGYTEPDPRDDLAGTDVA 779
Query: 238 RKALILARILGRRINMDSIQIESLYPKEMGPDVMTDDDFLSCGLLLLDKDIQERVEKAAS 297
RK +ILAR G ++ + I ++SL P+ + + + ++FL L D D+ + E A +
Sbjct: 780 RKVIILARGSGLKLELSDIPVQSLVPEPL-RGIASAEEFL-LQLPQFDSDMTRKREDAEN 837
Query: 298 NGNVLRYVCVIEGPRCEVGIQEL---PKNSALGRLRGSDNVLEVYTRCYSNQPLVIQGAG 354
G VLRYV V++ + G+ EL K +L GSDN+ T Y+ QP +I+G G
Sbjct: 838 AGEVLRYVGVVDAVN-QKGVVELKRYKKEHPFAQLSGSDNINAFTTERYNKQPPIIRGPG 896
Query: 355 AGNDTTAAGVLADIV 369
AG + TA GV +DI+
Sbjct: 897 AGAEVTAGGVFSDIL 911
>DHOM_SCHPO (O94671) Probable homoserine dehydrogenase (EC 1.1.1.3)
(HDH)
Length = 376
Score = 150 bits (378), Expect = 7e-36
Identities = 96/271 (35%), Positives = 150/271 (54%), Gaps = 14/271 (5%)
Query: 113 VDCTASSDTIVVLKQVVDLGCCVVMANKKPLTSTMGDFEKLLTYPRR----IRHESTVGA 168
VD TAS + + + NKK +++ ++ ++ + + HE++VGA
Sbjct: 96 VDNTASEAIAQSYPKFLSKKINIATPNKKAFSASNDVYQNIIKASKESGALLMHEASVGA 155
Query: 169 GLPVISSLNRIISSGDPVNRIIGSLSGTLGYVMSEVE-DGKP----LSQVVRAAKSLGYT 223
GLP+IS+L +I++GD + +I G SGTL Y+ + +GK S +V+ AK GYT
Sbjct: 156 GLPIISTLKELIATGDEIIKIEGIFSGTLSYIFNVWSPNGKKGTASFSDIVKIAKQNGYT 215
Query: 224 EPDPRDDLGGMDVARKALILARILGRRI-NMDSIQIESLYPKEMGPDVMTDDDFLSCGLL 282
EPDPRDDL GMDVARK IL+RI G + + S ++SL P+ + + ++FL+ GL
Sbjct: 216 EPDPRDDLNGMDVARKVTILSRIAGVHVESASSFPVKSLIPEPL-KSAVNAEEFLA-GLP 273
Query: 283 LLDKDIQERVEKAASNGNVLRYV--CVIEGPRCEVGIQELPKNSALGRLRGSDNVLEVYT 340
D + E+A G V+R+V + V +++ + L+ SDN++ T
Sbjct: 274 NFDSEFASMREEAEKEGKVVRFVGEADVANKTTLVKLEKYDASHPFANLQSSDNIISFTT 333
Query: 341 RCYSNQPLVIQGAGAGNDTTAAGVLADIVDI 371
+ Y +PLV+ GAGAG TAAGVL D++ I
Sbjct: 334 KRYHTRPLVVIGAGAGAAVTAAGVLGDMIKI 364
>AK2H_ECOLI (P00562) Bifunctional aspartokinase/homoserine
dehydrogenase II (AKII-HDII) [Includes: Aspartokinase II
(EC 2.7.2.4); Homoserine dehydrogenase II (EC 1.1.1.3)]
Length = 809
Score = 145 bits (367), Expect = 1e-34
Identities = 118/373 (31%), Positives = 177/373 (46%), Gaps = 32/373 (8%)
Query: 2 KTIPLILMGCGGVGSHLLQHIVSSRS-LHSSQGLCLRVVGIGDSKSLVVVDDLLNKGFDD 60
K I L+L G G +GS L+ +S L + G + G+ DS+ ++ D G D
Sbjct: 456 KRIGLVLFGKGNIGSRWLELFAREQSTLSARTGFEFVLAGVVDSRRSLLSYD----GLDA 511
Query: 61 SFLLELCRLKHGGESLSKLGDLGQCQVFVHPESEGKILEIASQLGKKTGLAFVDCTASSD 120
S L E++ + + + HP + L +D TAS
Sbjct: 512 SRALAF----FNDEAVEQDEESLFLWMRAHPYDD---------------LVVLDVTASQQ 552
Query: 121 TIVVLKQVVDLGCCVVMANKKPLTSTMGDFEKLL-TYPRRIRH---ESTVGAGLPVISSL 176
G V+ ANK S + ++ + + RH +TVGAGLP+ ++
Sbjct: 553 LADQYLDFASHGFHVISANKLAGASDSNKYRQIHDAFEKTGRHWLYNATVGAGLPINHTV 612
Query: 177 NRIISSGDPVNRIIGSLSGTLGYVMSEVEDGKPLSQVVRAAKSLGYTEPDPRDDLGGMDV 236
+I SGD + I G SGTL ++ + + P +++V A G TEPDPRDDL G DV
Sbjct: 613 RDLIDSGDTILSISGIFSGTLSWLFLQFDGSVPFTELVDQAWQQGLTEPDPRDDLSGKDV 672
Query: 237 ARKALILARILGRRINMDSIQIESLYPKEMGPDVMTDDDFLSCGLLLLDKDIQERVEKAA 296
RK +ILAR G I D +++ESL P + + D F G L ++ +Q R+E A
Sbjct: 673 MRKLVILAREAGYNIEPDQVRVESLVPAHC--EGGSIDHFFENGDELNEQMVQ-RLEAAR 729
Query: 297 SNGNVLRYVCVIE-GPRCEVGIQELPKNSALGRLRGSDNVLEVYTRCYSNQPLVIQGAGA 355
G VLRYV + + VG++ + ++ L L DNV + +R Y + PLVI+G GA
Sbjct: 730 EMGLVLRYVARFDANGKARVGVEAVREDHPLASLLPCDNVFAIESRWYRDNPLVIRGPGA 789
Query: 356 GNDTTAAGVLADI 368
G D TA + +DI
Sbjct: 790 GRDVTAGAIQSDI 802
>DHOM_BACSU (P19582) Homoserine dehydrogenase (EC 1.1.1.3) (HDH)
Length = 433
Score = 81.3 bits (199), Expect = 4e-15
Identities = 59/217 (27%), Positives = 110/217 (50%), Gaps = 30/217 (13%)
Query: 160 IRHESTVGAGLPVISSLNRIISSGDPVNRIIGSLSGTLGYVMSE-VEDGKPLSQVVRAAK 218
I E++V G+P++ +L +SS D + +++G ++GT +++++ +++ P +V++ A+
Sbjct: 126 IYFEASVAGGIPILRTLEEGLSS-DRITKMMGIVNGTTNFILTKMIKEKSPYEEVLKEAQ 184
Query: 219 SLGYTEPDPRDDLGGMDVARKALILARILGRRINMDSIQIESLYPKEMGPDVMTDDDFLS 278
LG+ E DP D+ G+D ARK ILAR LG +N+D + K G +TD+D
Sbjct: 185 DLGFAEADPTSDVEGLDAARKMAILAR-LGFSMNVDLEDV-----KVKGISQITDED--- 235
Query: 279 CGLLLLDKDIQERVEKAASNGNVLRYVCVI--EGPRCEVGIQE--LPKNSALGRLRGSDN 334
+ + G ++ + + +G + EV +Q LP + L + N
Sbjct: 236 -------------ISFSKRLGYTMKLIGIAQRDGSKIEVSVQPTLLPDHHPLSAVHNEFN 282
Query: 335 VLEVYTRCYSNQPLVIQGAGAGNDTTAAGVLADIVDI 371
+ VY + G GAG+ TA V++D+V +
Sbjct: 283 AVYVYGEAVGE--TMFYGPGAGSMPTATSVVSDLVAV 317
>DHOM_LACLC (P52985) Homoserine dehydrogenase (EC 1.1.1.3) (HDH)
Length = 428
Score = 80.9 bits (198), Expect = 5e-15
Identities = 75/253 (29%), Positives = 115/253 (44%), Gaps = 31/253 (12%)
Query: 125 LKQVVDLGCCVVMANKKPLTSTMGDFEKLLT-YPRRIRHESTVGAGLPVISSLNRIISSG 183
+ Q ++ G VV ANK L + L + + +E+ V G+P++ +L SS
Sbjct: 91 ITQAIEAGKNVVTANKDLLAVHGVELRSLAQKHHVALYYEAAVAGGIPILRTLANSFSS- 149
Query: 184 DPVNRIIGSLSGTLGYVMSEV-EDGKPLSQVVRAAKSLGYTEPDPRDDLGGMDVARKALI 242
D + ++G L+GT ++M+++ E+G + + A+ LGY E DP +D+ G+D + K I
Sbjct: 150 DKITHLLGILNGTSNFMMTKMSEEGWTYDESLAKAQELGYAESDPTNDVDGIDASYKLAI 209
Query: 243 LARILGRRINMDSIQIESLYPKEMGPDVMTDDDFLSCGLLLLDKDIQERVEKAASNGNVL 302
L+ E + + P DD GL + K VE A G VL
Sbjct: 210 LS--------------EFAFGMTLAP-----DDIAKSGLRSIQK---TDVEIAQQFGYVL 247
Query: 303 RYVCVI----EGPRCEVGIQELPKNSALGRLRGSDNVLEVYTRCYSNQPLVIQGAGAGND 358
+ I G EV LPK+ L + G N + + + + V GAGAG
Sbjct: 248 KLTGEINEVDSGIFAEVSPTFLPKSHPLASVNGVMNAVFIESEGIGDS--VFYGAGAGQK 305
Query: 359 TTAAGVLADIVDI 371
TA VLADIV I
Sbjct: 306 PTATSVLADIVRI 318
>DHOM_LACLA (Q9CGD8) Homoserine dehydrogenase (EC 1.1.1.3) (HDH)
Length = 428
Score = 75.5 bits (184), Expect = 2e-13
Identities = 74/254 (29%), Positives = 116/254 (45%), Gaps = 33/254 (12%)
Query: 125 LKQVVDLGCCVVMANKKPLTSTMGDFEKLLTYPRRIR--HESTVGAGLPVISSLNRIISS 182
+ +V+ G VV ANK L + G + L + +E+ V G+P++ +L SS
Sbjct: 91 ITKVIKAGKNVVTANKD-LLAVHGTELRALAEKHHVALYYEAAVAGGIPILRTLANSFSS 149
Query: 183 GDPVNRIIGSLSGTLGYVMSEV-EDGKPLSQVVRAAKSLGYTEPDPRDDLGGMDVARKAL 241
D + ++G L+GT ++M+++ E+ Q + A+ LGY E DP +D+ G+D + K
Sbjct: 150 -DKITHLLGILNGTSNFMMTKMSEEAWTYDQSLAKAQELGYAESDPTNDVDGIDASYKLA 208
Query: 242 ILARILGRRINMDSIQIESLYPKEMGPDVMTDDDFLSCGLLLLDKDIQERVEKAASNGNV 301
IL+ E + + PD ++ GL + K VE A G V
Sbjct: 209 ILS--------------EFAFGMTLSPDQIS-----KSGLRTIQK---TDVEIAQQFGYV 246
Query: 302 LRYVCVI----EGPRCEVGIQELPKNSALGRLRGSDNVLEVYTRCYSNQPLVIQGAGAGN 357
L+ I G EV LPK+ L + G N + + + + + GAGAG
Sbjct: 247 LKLTGEINEVESGIFAEVSPTFLPKSHPLASVNGVMNAVFIESDGIGDS--MFYGAGAGQ 304
Query: 358 DTTAAGVLADIVDI 371
TA VLADIV I
Sbjct: 305 KPTATSVLADIVRI 318
>DHOM_MYCLE (P46806) Homoserine dehydrogenase (EC 1.1.1.3) (HDH)
Length = 441
Score = 75.1 bits (183), Expect = 3e-13
Identities = 70/241 (29%), Positives = 106/241 (43%), Gaps = 20/241 (8%)
Query: 132 GCCVVMANKKPLTSTMGDFEKLLTYPR-RIRHESTVGAGLPVISSLNRIISSGDPVNRII 190
G VV ANK L ++ G+ + + E+ V +PVI L + ++ GD V R+
Sbjct: 99 GKSVVTANKALLAASTGELAQAAESAHVDLYFEAAVAGAIPVIRPLTQSLA-GDTVLRVA 157
Query: 191 GSLSGTLGYVMSEVED-GKPLSQVVRAAKSLGYTEPDPRDDLGGMDVARKALILARI-LG 248
G ++GT Y++S ++ G + A++LGY E DP D+ G D A KA ILA I
Sbjct: 158 GIVNGTTNYILSAMDSTGADYDSALAGARALGYAEADPTADVEGHDAAAKAAILASIAFH 217
Query: 249 RRINMDSIQIESLYPKEMGPDVMTDDDFLSCGLLLLDKDIQERVEKAASNGNVLRYVCVI 308
R+ D + E + ++ P L C + LL I ER+ A V
Sbjct: 218 TRVTADDVYREGI--TKITPADFVSARALGCTIKLL--FICERITAADGQQRV------- 266
Query: 309 EGPRCEVGIQELPKNSALGRLRGSDNVLEVYTRCYSNQPLVIQGAGAGNDTTAAGVLADI 368
V +P + L + G+ N + V L+ G GAG TA+ V D+
Sbjct: 267 ---SARVYPALVPMSHPLATVSGAFNAVVVEAEAAGR--LMFYGQGAGGAPTASAVTGDL 321
Query: 369 V 369
V
Sbjct: 322 V 322
>DHOM_MYCTU (P63629) Homoserine dehydrogenase (EC 1.1.1.3) (HDH)
Length = 441
Score = 73.9 bits (180), Expect = 6e-13
Identities = 69/244 (28%), Positives = 108/244 (43%), Gaps = 20/244 (8%)
Query: 129 VDLGCCVVMANKKPLTSTMGDFEKLLTYPR-RIRHESTVGAGLPVISSLNRIISSGDPVN 187
++ G VV ANK L ++ G+ + + E+ V +PVI L + ++ GD V
Sbjct: 96 LERGKSVVTANKALLATSTGELAQAAESAHVDLYFEAAVAGAIPVIRPLTQSLA-GDTVL 154
Query: 188 RIIGSLSGTLGYVMSEVED-GKPLSQVVRAAKSLGYTEPDPRDDLGGMDVARKALILARI 246
R+ G ++GT Y++S ++ G + + A +LGY E DP D+ G D A KA ILA I
Sbjct: 155 RVAGIVNGTTNYILSAMDSTGADYASALADASALGYAEADPTADVEGYDAAAKAAILASI 214
Query: 247 -LGRRINMDSIQIESLYPKEMGPDVMTDDDFLSCGLLLLDKDIQERVEKAASNGNVLRYV 305
R+ D + E + ++ P L C + LL I ER+ + V
Sbjct: 215 AFHTRVTADDVYREGI--TKVTPADFGSAHALGCTIKLL--SICERITTDEGSQRV---- 266
Query: 306 CVIEGPRCEVGIQELPKNSALGRLRGSDNVLEVYTRCYSNQPLVIQGAGAGNDTTAAGVL 365
V +P + L + G+ N + V L+ G GAG TA+ V
Sbjct: 267 ------SARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGR--LMFYGQGAGGAPTASAVT 318
Query: 366 ADIV 369
D+V
Sbjct: 319 GDLV 322
>DHOM_MYCBO (P63630) Homoserine dehydrogenase (EC 1.1.1.3) (HDH)
Length = 441
Score = 73.9 bits (180), Expect = 6e-13
Identities = 69/244 (28%), Positives = 108/244 (43%), Gaps = 20/244 (8%)
Query: 129 VDLGCCVVMANKKPLTSTMGDFEKLLTYPR-RIRHESTVGAGLPVISSLNRIISSGDPVN 187
++ G VV ANK L ++ G+ + + E+ V +PVI L + ++ GD V
Sbjct: 96 LERGKSVVTANKALLATSTGELAQAAESAHVDLYFEAAVAGAIPVIRPLTQSLA-GDTVL 154
Query: 188 RIIGSLSGTLGYVMSEVED-GKPLSQVVRAAKSLGYTEPDPRDDLGGMDVARKALILARI 246
R+ G ++GT Y++S ++ G + + A +LGY E DP D+ G D A KA ILA I
Sbjct: 155 RVAGIVNGTTNYILSAMDSTGADYASALADASALGYAEADPTADVEGYDAAAKAAILASI 214
Query: 247 -LGRRINMDSIQIESLYPKEMGPDVMTDDDFLSCGLLLLDKDIQERVEKAASNGNVLRYV 305
R+ D + E + ++ P L C + LL I ER+ + V
Sbjct: 215 AFHTRVTADDVYREGI--TKVTPADFGSAHALGCTIKLL--SICERITTDEGSQRV---- 266
Query: 306 CVIEGPRCEVGIQELPKNSALGRLRGSDNVLEVYTRCYSNQPLVIQGAGAGNDTTAAGVL 365
V +P + L + G+ N + V L+ G GAG TA+ V
Sbjct: 267 ------SARVYPALVPLSHPLAAVNGAFNAVVVEAEAAGR--LMFYGQGAGGAPTASAVT 318
Query: 366 ADIV 369
D+V
Sbjct: 319 GDLV 322
>DHOM_METJA (Q58997) Homoserine dehydrogenase (EC 1.1.1.3) (HDH)
Length = 336
Score = 73.9 bits (180), Expect = 6e-13
Identities = 86/371 (23%), Positives = 162/371 (43%), Gaps = 48/371 (12%)
Query: 6 LILMGCGGVGSHLLQHIVSSRSLHSSQGLCLRVVGIGDSKSLVVVDDLLNKGFDDSFLLE 65
+I++G G +G + + + + +VV I DS + +D L+ LL+
Sbjct: 3 IIIVGFGAIGKGIAKVLYDKKDYLKKNYEEFKVVAITDSSGAAIDEDGLD-------LLK 55
Query: 66 LCRLKHGGESLSKLGDLGQ--CQVFVHPESEGKILEIASQLGKKTGLAFVDCTASSDTIV 123
+K + + G+ + V E + ++ + +TG A + +
Sbjct: 56 AIEVKEKTGKIKNYPEKGREMSSIDVIKEVDADVVVEVTPSNLETG-----DPAKTHILE 110
Query: 124 VLKQVVDLGCCVVMANKKPLTSTMGDF-EKLLTYPRRIRHESTVGAGLPVISSLNRIISS 182
K VV ANK PL + E+ + RHE++VG +P+I+ ++
Sbjct: 111 SFKNKKH----VVTANKGPLALCYKELIEEAKKHGVIFRHEASVGGAMPIINLAKETLA- 165
Query: 183 GDPVNRIIGSLSGTLGYVMSEVE-DGKPLSQVVRAAKSLGYTEPDPRDDLGGMDVARKAL 241
G+ + I G L+GT Y+++++E +G ++ AK LG E DP D+ G+D A K +
Sbjct: 166 GNEILSIRGILNGTTNYILTKMEKEGLDFETALKEAKELGIAETDPTQDIEGLDTAAKIV 225
Query: 242 ILAR-ILGRRINMDSIQIESLYPKEMGPDVMTDDDFLSCGLLLLDKDIQERVEKAASNGN 300
ILA I+G + ++++ + + P+ + FL A G
Sbjct: 226 ILANSIMGMNKTIKDVKVKGI--SRITPEAL----FL-----------------ANKRGY 262
Query: 301 VLRYVCVIEGPRCEVGIQELPKNSALGRLRGSDNVLEVYTRCYSNQPLVIQGAGAGNDTT 360
++ + I+ V +P +S L ++G+ NV T + +V+ G GAG T
Sbjct: 263 TIKLIGQIKDGYLIVEPMLVPIDSPL-NVKGTLNVAMFETDL--AKEVVVVGRGAGPIET 319
Query: 361 AAGVLADIVDI 371
A+ +L+D++ I
Sbjct: 320 ASAILSDLIHI 330
>DHOM_PSEAE (P29365) Homoserine dehydrogenase (EC 1.1.1.3) (HDH)
Length = 434
Score = 73.2 bits (178), Expect = 1e-12
Identities = 73/253 (28%), Positives = 117/253 (45%), Gaps = 28/253 (11%)
Query: 123 VVLKQVVDLGCCVVMANKKPLTSTMGD--FEKLLTYPRRIRHESTVGAGLPVISSLNRII 180
+VLK ++ G VV ANK L + G+ F K + E+ V G+PVI ++ +
Sbjct: 87 LVLK-AIENGKHVVTANKA-LIAVHGNEIFAKAREKGVIVAFEAAVAGGIPVIKAIREGL 144
Query: 181 SSGDPVNRIIGSLSGTLGYVMSEV-EDGKPLSQVVRAAKSLGYTEPDPRDDLGGMDVARK 239
S+ + +N + G ++GT +++SE+ E G+ V+ A++LGY E DP D+ G+D A K
Sbjct: 145 SA-NRINWLAGIINGTGNFILSEMREKGRTFPDVLAEAQALGYAEADPTFDVEGIDAAHK 203
Query: 240 ALILARI-LGRRINMDSIQIESLYPKEMGPDVMTDDDFLSCGLLLLDKDIQERVEKAASN 298
ILA I G + D E + K DV D + G + + R E
Sbjct: 204 LTILASIAFGIPLQFDKAYTEGI-SKLTSADVNYAD---ALGYRIKHLGVARRTE----- 254
Query: 299 GNVLRYVCVIEGPRCEVGIQELPKNSALGRLRGSDNVLEVYTRCYSNQPLVIQGAGAGND 358
G V +P + + + G N + V + + GAGAG +
Sbjct: 255 ----------SGFELRVHPTLIPSDRLIANVNGVMNAVMVNGDAVGS--TLYYGAGAGME 302
Query: 359 TTAAGVLADIVDI 371
TA+ V+AD+VD+
Sbjct: 303 PTASSVVADLVDV 315
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.319 0.139 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,622,334
Number of Sequences: 164201
Number of extensions: 1859699
Number of successful extensions: 4911
Number of sequences better than 10.0: 39
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 4811
Number of HSP's gapped (non-prelim): 54
length of query: 376
length of database: 59,974,054
effective HSP length: 112
effective length of query: 264
effective length of database: 41,583,542
effective search space: 10978055088
effective search space used: 10978055088
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Medicago: description of AC146743.7