BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC146631.5 - phase: 0 /pseudo
(359 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AVT1_YEAST (P47082) Vacuolar amino acid transporter 1 126 1e-28
VIAA_MOUSE (O35633) Vesicular inhibitory amino acid transporter ... 88 4e-17
VIAA_RAT (O35458) Vesicular inhibitory amino acid transporter (G... 87 7e-17
VIAA_MACFA (Q95KE2) Vesicular inhibitory amino acid transporter ... 87 7e-17
VIAA_HUMAN (Q9H598) Vesicular inhibitory amino acid transporter ... 87 7e-17
UN47_CAEEL (P34579) Vesicular GABA transporter (Uncoordinated pr... 86 2e-16
S361_HUMAN (Q7Z2H8) Proton-coupled amino acid transporter 1 (Pro... 70 1e-11
S361_RAT (Q924A5) Proton-coupled amino acid transporter 1 (Proto... 65 3e-10
S361_MOUSE (Q8K4D3) Proton-coupled amino acid transporter 1 (Pro... 64 5e-10
AVT4_YEAST (P50944) Vacuolar amino acid transporter 4 61 4e-09
YMJ2_CAEEL (P34479) Hypothetical protein F59B2.2 in chromosome III 53 1e-06
AVT7_YEAST (P40501) Vacuolar amino acid transporter 7 52 2e-06
YAN9_SCHPO (Q10074) Hypothetical protein C3H1.09c in chromosome I 50 9e-06
MTR_NEUCR (P38680) N amino acid transport system protein (Methyl... 49 2e-05
TYRP_HAEIN (P44727) Tyrosine-specific transport protein 1 (Tyros... 47 7e-05
AVT3_YEAST (P36062) Vacuolar amino acid transporter 3 47 7e-05
YSPK_CAEEL (Q19425) Hypothetical protein F13H10.3 in chromosome IV 46 1e-04
S383_RAT (Q9JHZ9) System N amino acid transporter 1 (SN1) (N-sys... 45 2e-04
S383_MOUSE (Q9DCP2) System N amino acid transporter 1 (SN1) (N-s... 44 6e-04
AVT6_YEAST (P40074) Vacuolar amino acid transporter 6 41 0.005
>AVT1_YEAST (P47082) Vacuolar amino acid transporter 1
Length = 602
Score = 126 bits (316), Expect = 1e-28
Identities = 85/258 (32%), Positives = 132/258 (50%), Gaps = 21/258 (8%)
Query: 94 QTVFNGINVMAGVGLLSTPYTVKQAGWM-GLVLMLIFASVCCYTATLMRHCFESREGLTS 152
QT+FN INV+ G+GLL+ P +K AGW+ GL ++ IFA TA L+ C ++ L S
Sbjct: 212 QTIFNSINVLIGIGLLALPLGLKYAGWVIGLTMLAIFALATFCTAELLSRCLDTDPTLIS 271
Query: 153 YPDIGEAAFGRYGRIFVSIILYTELYSYCVEFITLEGDNLTGLFPGTSLDIGGLHLDSMH 212
Y D+G AAFG GR +S + +L V + L GD+L LFP S
Sbjct: 272 YADLGYAAFGTKGRALISALFTLDLLGSGVSLVILFGDSLNALFPQYSTT---------- 321
Query: 213 LFGVLTALVILPTVWLKDLRVISYLSVGGI---AATILII-----ISVFSVGTTVGFHHT 264
F +++ ++ P V++ L V+S +S+ GI T+L+I S G+ V T
Sbjct: 322 FFKIVSFFIVTPPVFI-PLSVLSNISLLGILSTTGTVLVICCCGLYKSSSPGSLVNPMET 380
Query: 265 GR-VVNWSGIPFAIGVYGFCFAGHSVFPNIYQSMADKKQYTKALITCFVLCILIYGSVAV 323
++ + +IG+ C+ GH+VFPN+ M ++ L T + + + AV
Sbjct: 381 SMWPIDLKHLCLSIGLLSACWGGHAVFPNLKTDMRHPDKFKDCLKTTYKITSVTDIGTAV 440
Query: 324 MGFLSFGDDTLSQITLNM 341
+GFL FG+ +IT N+
Sbjct: 441 IGFLMFGNLVKDEITKNV 458
>VIAA_MOUSE (O35633) Vesicular inhibitory amino acid transporter
(GABA and glycine transporter) (Vesicular GABA
transporter) (mVIAAT) (mVGAT)
Length = 525
Score = 87.8 bits (216), Expect = 4e-17
Identities = 65/278 (23%), Positives = 122/278 (43%), Gaps = 24/278 (8%)
Query: 97 FNGINVMAGVGLLSTPYTVKQAGWMGLVLMLIFASVCCYTATLMRHCF--ESREG----- 149
+N N + G+ +L PY + G++GL L++ A VCCYT ++ C E+ +G
Sbjct: 123 WNVTNAIQGMFVLGLPYAILHGGYLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVVRV 182
Query: 150 LTSYPDIGEAA----FGRYGRIFVSIILYTELYSYCVEFITLEGDNLTGLFPGTSLDIGG 205
SY I A F G V++ EL C+ ++ + G+ + FPG +
Sbjct: 183 RDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLPV---- 238
Query: 206 LHLDSMHLFGVLTALVILPTVWLKDLRVISYLS----VGGIAATILIIISVFSVGTTVGF 261
S + ++ V+LP +LK+L+ +S S + IL+I S +
Sbjct: 239 ----SQKSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAW 294
Query: 262 HHTGRVVNWSGIPFAIGVYGFCFAGHSVFPNIYQSMADKKQYTKALITCFVLCILIYGSV 321
++ P +IG+ F + P++ +M ++ + + ++ G
Sbjct: 295 EKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLF 354
Query: 322 AVMGFLSFGDDTLSQITLNMPAGAFASKVALWTTTNML 359
A++ +L++ D+T IT N+P G+ + V L+ L
Sbjct: 355 ALVAYLTWADETKEVITDNLP-GSIRAVVNLFLVAKAL 391
>VIAA_RAT (O35458) Vesicular inhibitory amino acid transporter (GABA
and glycine transporter) (Vesicular GABA transporter)
(rGVAT)
Length = 525
Score = 87.0 bits (214), Expect = 7e-17
Identities = 61/261 (23%), Positives = 115/261 (43%), Gaps = 23/261 (8%)
Query: 97 FNGINVMAGVGLLSTPYTVKQAGWMGLVLMLIFASVCCYTATLMRHCF--ESREG----- 149
+N N + G+ +L PY + G++GL L++ A VCCYT ++ C E+ +G
Sbjct: 123 WNVTNAIQGMFVLGLPYAILHGGYLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVVRV 182
Query: 150 LTSYPDIGEAA----FGRYGRIFVSIILYTELYSYCVEFITLEGDNLTGLFPGTSLDIGG 205
SY I A F G V++ EL C+ ++ + G+ + FPG +
Sbjct: 183 RDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLPV---- 238
Query: 206 LHLDSMHLFGVLTALVILPTVWLKDLRVISYLS----VGGIAATILIIISVFSVGTTVGF 261
S + ++ V+LP +LK+L+ +S S + IL+I S +
Sbjct: 239 ----SQKSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAW 294
Query: 262 HHTGRVVNWSGIPFAIGVYGFCFAGHSVFPNIYQSMADKKQYTKALITCFVLCILIYGSV 321
++ P +IG+ F + P++ +M ++ + + ++ G
Sbjct: 295 EKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLF 354
Query: 322 AVMGFLSFGDDTLSQITLNMP 342
A++ +L++ D+T IT N+P
Sbjct: 355 ALVAYLTWADETKEVITDNLP 375
>VIAA_MACFA (Q95KE2) Vesicular inhibitory amino acid transporter
(GABA and glycine transporter) (Vesicular GABA
transporter) (QccE-21148)
Length = 525
Score = 87.0 bits (214), Expect = 7e-17
Identities = 61/261 (23%), Positives = 115/261 (43%), Gaps = 23/261 (8%)
Query: 97 FNGINVMAGVGLLSTPYTVKQAGWMGLVLMLIFASVCCYTATLMRHCF--ESREG----- 149
+N N + G+ +L PY + G++GL L++ A VCCYT ++ C E+ +G
Sbjct: 123 WNVTNAIQGMFVLGLPYAILHGGYLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVVRV 182
Query: 150 LTSYPDIGEAA----FGRYGRIFVSIILYTELYSYCVEFITLEGDNLTGLFPGTSLDIGG 205
SY I A F G V++ EL C+ ++ + G+ + FPG +
Sbjct: 183 RDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLPV---- 238
Query: 206 LHLDSMHLFGVLTALVILPTVWLKDLRVISYLS----VGGIAATILIIISVFSVGTTVGF 261
S + ++ V+LP +LK+L+ +S S + IL+I S +
Sbjct: 239 ----SQKSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAW 294
Query: 262 HHTGRVVNWSGIPFAIGVYGFCFAGHSVFPNIYQSMADKKQYTKALITCFVLCILIYGSV 321
++ P +IG+ F + P++ +M ++ + + ++ G
Sbjct: 295 EKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLF 354
Query: 322 AVMGFLSFGDDTLSQITLNMP 342
A++ +L++ D+T IT N+P
Sbjct: 355 ALVAYLTWADETKEVITDNLP 375
>VIAA_HUMAN (Q9H598) Vesicular inhibitory amino acid transporter
(GABA and glycine transporter) (Vesicular GABA
transporter) (hVIAAT)
Length = 525
Score = 87.0 bits (214), Expect = 7e-17
Identities = 61/261 (23%), Positives = 115/261 (43%), Gaps = 23/261 (8%)
Query: 97 FNGINVMAGVGLLSTPYTVKQAGWMGLVLMLIFASVCCYTATLMRHCF--ESREG----- 149
+N N + G+ +L PY + G++GL L++ A VCCYT ++ C E+ +G
Sbjct: 123 WNVTNAIQGMFVLGLPYAILHGGYLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVVRV 182
Query: 150 LTSYPDIGEAA----FGRYGRIFVSIILYTELYSYCVEFITLEGDNLTGLFPGTSLDIGG 205
SY I A F G V++ EL C+ ++ + G+ + FPG +
Sbjct: 183 RDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLPV---- 238
Query: 206 LHLDSMHLFGVLTALVILPTVWLKDLRVISYLS----VGGIAATILIIISVFSVGTTVGF 261
S + ++ V+LP +LK+L+ +S S + IL+I S +
Sbjct: 239 ----SQKSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAW 294
Query: 262 HHTGRVVNWSGIPFAIGVYGFCFAGHSVFPNIYQSMADKKQYTKALITCFVLCILIYGSV 321
++ P +IG+ F + P++ +M ++ + + ++ G
Sbjct: 295 EKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLF 354
Query: 322 AVMGFLSFGDDTLSQITLNMP 342
A++ +L++ D+T IT N+P
Sbjct: 355 ALVAYLTWADETKEVITDNLP 375
>UN47_CAEEL (P34579) Vesicular GABA transporter (Uncoordinated
protein 47) (Protein unc-47)
Length = 486
Score = 85.5 bits (210), Expect = 2e-16
Identities = 66/271 (24%), Positives = 122/271 (44%), Gaps = 23/271 (8%)
Query: 91 SYTQTVFNGINVMAGVGLLSTPYTVKQAGWMGLVLMLIFASVCCYTATLMRHCF-----E 145
S Q +N N + G+ ++ P VK GW + M+ A VC +T L+ C +
Sbjct: 90 SALQAAWNVTNAIQGMFIVGLPIAVKVGGWWSIGAMVGVAYVCYWTGVLLIECLYENGVK 149
Query: 146 SREGLTSYPDIGEAAFGRYGRIFVSIILYTELYSYCVEFITLEGDNLTGLFPGTSLDIGG 205
R+ D + FG++ V TEL S C+ ++ L D L FP S+D G
Sbjct: 150 KRKTYREIADFYKPGFGKW----VLAAQLTELLSTCIIYLVLAADLLQSCFP--SVDKAG 203
Query: 206 LHLDSMHLFGVLTALVILPTVWLKDLRVISYLS----VGGIAATILIIISVFSVGTTVGF 261
+ ++T+ +L +L DL+++S LS + + +++++ S + F
Sbjct: 204 --------WMMITSASLLTCSFLDDLQIVSRLSFFNAISHLIVNLIMVLYCLSFVSQWSF 255
Query: 262 HHTGRVVNWSGIPFAIGVYGFCFAGHSVFPNIYQSMADKKQYTKALITCFVLCILIYGSV 321
+N + +P +G+ F + H PN+ +M + Q+ L + +
Sbjct: 256 STITFSLNINTLPTIVGMVVFGYTSHIFLPNLEGNMKNPAQFNVMLKWSHIAAAVFKVVF 315
Query: 322 AVMGFLSFGDDTLSQITLNMPAGAFASKVAL 352
++GFL+FG+ T +I+ ++P +F V L
Sbjct: 316 GMLGFLTFGELTQEEISNSLPNQSFKILVNL 346
>S361_HUMAN (Q7Z2H8) Proton-coupled amino acid transporter 1
(Proton/amino acid transporter 1) (Solute carrier family
36 member 1)
Length = 476
Score = 69.7 bits (169), Expect = 1e-11
Identities = 68/282 (24%), Positives = 112/282 (39%), Gaps = 32/282 (11%)
Query: 91 SYTQTVFNGINVMAGVGLLSTPYTVKQAGW-MGLVLMLIFASVCCYTATLMRHCFES--R 147
++ QT+ + + G GLL P VK AG MG + +LI V + ++ C R
Sbjct: 48 TWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCR 107
Query: 148 EGLTSYPDIGEAAF--------------GRYGRIFVSIILYTELYSYCVEFITLEGDNLT 193
S+ D G+ +GR V L +C + DN
Sbjct: 108 RLNKSFVDYGDTVMYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFK 167
Query: 194 GLFPGTSLDIGGLH----------LDS-MHLFGVLTALVILPTVWLKDLRVISYLSV-GG 241
+ + H +DS +++ L LV+L V++++LR +S S+
Sbjct: 168 QVIEAANGTTNNCHNNETVILTPTMDSRLYMLSFLPFLVLL--VFIRNLRALSIFSLLAN 225
Query: 242 IAATI-LIIISVFSVGTTVGFHHTGRVVNWSGIPFAIGVYGFCFAGHSVFPNIYQSMADK 300
I + L++I F V H V W P G F F G + + M D
Sbjct: 226 ITMLVSLVMIYQFIVQRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDP 285
Query: 301 KQYTKALITCFVLCILIYGSVAVMGFLSFGDDTLSQITLNMP 342
+++ L V+ ++Y S+ +G+L FG + ITLN+P
Sbjct: 286 RKFPLILYLGMVIVTILYISLGCLGYLQFGANIQGSITLNLP 327
>S361_RAT (Q924A5) Proton-coupled amino acid transporter 1
(Proton/amino acid transporter 1) (Solute carrier family
36 member 1) (Lysosomal amino acid transporter 1)
(LYAAT-1) (Neutral amino acid/proton symporter)
Length = 475
Score = 65.1 bits (157), Expect = 3e-10
Identities = 71/289 (24%), Positives = 113/289 (38%), Gaps = 34/289 (11%)
Query: 86 LGYGCSYT--QTVFNGINVMAGVGLLSTPYTVKQAGWM-GLVLMLIFASVCCYTATLMRH 142
LG S T QT+ + + G GLL P VK AG + G + +L+ V + ++
Sbjct: 40 LGENSSMTWFQTLIHLLKGNIGTGLLGLPLAVKNAGLLLGPLSLLVIGIVAVHCMGILVK 99
Query: 143 CFES----------------REGLTSYPDIGEAAFGRYGRIFVSIILYTELYSYCVEFIT 186
C GL P +GR V L +C +
Sbjct: 100 CAHHLCRRLNKPFLDYGDTVMYGLECSPSTWIRNHSHWGRRIVDFFLVVTQLGFCCVYFV 159
Query: 187 LEGDNLTGLFP---GTSLDIGGLH-------LDS-MHLFGVLTALVILPTVWLKDLRVIS 235
DN + GT+ + +DS +++ L LV+L ++++LR++S
Sbjct: 160 FLADNFKQVIEAANGTTTNCNNNETVILTPTMDSRLYMLTFLPFLVLLS--FIRNLRILS 217
Query: 236 YLSV-GGIAATI-LIIISVFSVGTTVGFHHTGRVVNWSGIPFAIGVYGFCFAGHSVFPNI 293
S+ I+ + LI+I F V H V W P G F F G V +
Sbjct: 218 IFSLLANISMFVSLIMIYQFIVQRIPDPSHLPLVAPWKTYPLFFGTAIFAFEGIGVVLPL 277
Query: 294 YQSMADKKQYTKALITCFVLCILIYGSVAVMGFLSFGDDTLSQITLNMP 342
M D +++ L + ++Y S+ +G+L FG D ITLN+P
Sbjct: 278 ENKMKDSQKFPLILYLGMAIITVLYISLGSLGYLQFGADIKGSITLNLP 326
>S361_MOUSE (Q8K4D3) Proton-coupled amino acid transporter 1
(Proton/amino acid transporter 1) (Solute carrier family
36 member 1)
Length = 475
Score = 64.3 bits (155), Expect = 5e-10
Identities = 72/289 (24%), Positives = 114/289 (38%), Gaps = 34/289 (11%)
Query: 86 LGYGCSYT--QTVFNGINVMAGVGLLSTPYTVKQAGWM-GLVLMLIFASVCCYTATLMRH 142
LG S T QT+ + + G GLL P VK AG + G + +L+ V + ++
Sbjct: 40 LGENSSMTWFQTLIHLLKGNIGTGLLGLPLAVKNAGLLLGPLSLLVIGIVAVHCMGILVK 99
Query: 143 CFES----------------REGLTSYPDIGEAAFGRYGRIFVSIILYTELYSYCVEFIT 186
C GL P +GR V L +C +
Sbjct: 100 CAHHLCRRLNKPFLDYGDTVMYGLECSPSTWVRNHSHWGRRIVDFFLIVTQLGFCCVYFV 159
Query: 187 LEGDNLTGLFP---GTSLD-------IGGLHLDS-MHLFGVLTALVILPTVWLKDLRVIS 235
DN + GT+ + I +DS +++ L LV+L ++++LRV+S
Sbjct: 160 FLADNFKQVIEAANGTTTNCNNNVTVIPTPTMDSRLYMLSFLPFLVLLS--FIRNLRVLS 217
Query: 236 YLSV-GGIAATI-LIIISVFSVGTTVGFHHTGRVVNWSGIPFAIGVYGFCFAGHSVFPNI 293
S+ I+ + LI+I F V H V W P G F F G V +
Sbjct: 218 IFSLLANISMFVSLIMIYQFIVQRIPDPSHLPLVAPWKTYPLFFGTAIFAFEGIGVVLPL 277
Query: 294 YQSMADKKQYTKALITCFVLCILIYGSVAVMGFLSFGDDTLSQITLNMP 342
M D +++ L + ++Y S+ +G+L FG + ITLN+P
Sbjct: 278 ENKMKDSQKFPLILYLGMAIITVLYISLGSLGYLQFGANIKGSITLNLP 326
>AVT4_YEAST (P50944) Vacuolar amino acid transporter 4
Length = 713
Score = 61.2 bits (147), Expect = 4e-09
Identities = 64/274 (23%), Positives = 116/274 (41%), Gaps = 25/274 (9%)
Query: 84 MPLGYGCSYTQTVFNGI-NVMAGVGLLSTPYTVKQAGWMGLVLMLIFASVCCYTATLMRH 142
+P G + T+ VF + G G+L P G V ML F + Y +
Sbjct: 290 LPSAKGTTSTKKVFLILLKSFIGTGVLFLPNAFHNGGLFFSVSMLAFFGIYSYWCYYILV 349
Query: 143 CFESREGLTSYPDIGEAAFGRYGRIFVSIILYTELYSYCVEFITLEGDNLTGLFPGTSLD 202
+S G++S+ DIG +G + RI + L + ++ NL F
Sbjct: 350 QAKSSCGVSSFGDIGLKLYGPWMRIIILFSLVITQVGFSGAYMIFTAKNLQA-FLDNVFH 408
Query: 203 IGGLHLDSMHLFGVLTALVILPTVWLKDLRVISYLSVGGIAATI-----LIIISVFS--- 254
+G L L + +F ++ +P L +R IS LS+ + A L+I+ +F+
Sbjct: 409 VGVLPLSYLMVF---QTIIFIP---LSFIRNISKLSLPSLLANFFIMAGLVIVIIFTAKR 462
Query: 255 -----VGT-TVGFHHTGRVVNWSGIPFAIGVYGFCFAGHSVFPNIYQSMADKKQYTKALI 308
+GT +G + W+ IG F F G + + SM + +++ L
Sbjct: 463 LFFDLMGTPAMGVVYGLNADRWT---LFIGTAIFAFEGIGLIIPVQDSMRNPEKFPLVLA 519
Query: 309 TCFVLCILIYGSVAVMGFLSFGDDTLSQITLNMP 342
+ +++ S+A +G+L++G + + I LN+P
Sbjct: 520 LVILTATILFISIATLGYLAYGSNVQTVILLNLP 553
>YMJ2_CAEEL (P34479) Hypothetical protein F59B2.2 in chromosome III
Length = 460
Score = 53.1 bits (126), Expect = 1e-06
Identities = 62/299 (20%), Positives = 107/299 (35%), Gaps = 53/299 (17%)
Query: 93 TQTVFNGINVMAGVGLLSTPYTVKQAG-WMGLVLMLIFASVCCYTATLMRHCFESREGLT 151
T+ V M G S PY K G W+ V+ + A + Y ++ + + L
Sbjct: 40 TRAVLTLSKSMFNAGCFSLPYAWKLGGLWVSFVMSFVIAGLNWYGNHIL---VRASQHLA 96
Query: 152 SYPDIGEAAFGRYGR-------------------IFVSIILYTELYSYCVEFITLEGDNL 192
D +G + + FV++ + C I DNL
Sbjct: 97 KKSDRSALDYGHFAKKVCDYSDIRFLRNNSKAVMYFVNVTILFYQLGMCSVAILFISDNL 156
Query: 193 TGLFPGTSLDIGGLHLDSMHLFGVLTALVILPTVWLKDLRVISYLSVGGIAATILIIISV 252
L +GG M L ++ IL T ++R++S+ + L+
Sbjct: 157 VNLVGD---HLGGTRHQQMILMATVSLFFILLTNMFTEMRIVSFFA--------LVSSVF 205
Query: 253 FSVGTTVGFHHTGRVVN-WSGIPFA---------IGVYGFCFAGHSVFPNIYQSMADKKQ 302
F +G V +T + N W +P A IG+ + F G ++ I + +
Sbjct: 206 FVIGAAVIMQYTVQQPNQWDKLPAATNFTGTITMIGMSMYAFEGQTMILPIENKLDNPAA 265
Query: 303 YTK---ALITCFVLCILIYGSVAVMGFLSFGDDTLSQITLNMPAGAFASKVALWTTTNM 358
+ L T ++C ++ G+ FGD IT N+P K L++T N+
Sbjct: 266 FLAPFGVLSTTMIICTAFMTALGFFGYTGFGDSIAPTITTNVP------KEGLYSTVNV 318
>AVT7_YEAST (P40501) Vacuolar amino acid transporter 7
Length = 490
Score = 52.0 bits (123), Expect = 2e-06
Identities = 56/259 (21%), Positives = 110/259 (41%), Gaps = 28/259 (10%)
Query: 98 NGINVMAGVGLLSTPYTVKQAGWM-GLVLMLIFASVCCYTATLMRHCFES--REGLTSYP 154
N + + G G L+ PY+ K G + G++L L+ A ++ C ++ +S+
Sbjct: 13 NLVKTIVGAGTLAIPYSFKSDGVLVGVILTLLAAVTSGLGLFVLSKCSKTLINPRNSSFF 72
Query: 155 DIGEAAFGRYGRIFVSIILYTELYSYCVEFITLEGDNLTGLFPGTSLDIGGLHLDSMHLF 214
+ + IF + + + + + ++ L GD GLF G + +
Sbjct: 73 TLCMLTYPTLAPIF-DLAMIVQCFGVGLSYLVLIGDLFPGLFGG-----------ERNYW 120
Query: 215 GVLTALVILPTVWLKDLRVISYLSVGGIAATILIIISVFS-------VGTTVGFHHTG-- 265
+ +A++I+P +K L + Y S+ G+ A I I VFS G
Sbjct: 121 IIASAVIIIPLCLVKKLDQLKYSSILGLFALAYISILVFSHFVFELGKGELTNILRNDIC 180
Query: 266 --RVVNWSGIPFAIGVYGFCFAGH-SVFPNIYQSMADK-KQYTKALITCFVLCILIYGSV 321
++ ++ G+ + F F G ++FP I + + + T + L ++ V
Sbjct: 181 WWKIHDFKGLLSTFSIIIFAFTGSMNLFPMINELKDNSMENITFVINNSISLSTALFLIV 240
Query: 322 AVMGFLSFGDDTLSQITLN 340
+ G+L+FG++TL + LN
Sbjct: 241 GLSGYLTFGNETLGNLMLN 259
>YAN9_SCHPO (Q10074) Hypothetical protein C3H1.09c in chromosome I
Length = 656
Score = 50.1 bits (118), Expect = 9e-06
Identities = 60/254 (23%), Positives = 101/254 (39%), Gaps = 25/254 (9%)
Query: 105 GVGLLSTPYTVKQAGWMGLVLMLIFASVCCYTATLMRH-CF----ESREGLT-SYPDIGE 158
G G+L P K G L+F+S ++ H CF ++R + S+ DIG
Sbjct: 290 GTGVLFLPKAFKLGG-------LVFSSATLLIVGVLSHICFLLLIQTRMKVPGSFGDIGG 342
Query: 159 AAFGRYGRIFVSIILYTELYSYCVEFITLEGDNLTGLFPGTSLDIGGLHLDSMHLFGVLT 218
+G + R + + + +I+ L S HL +F +
Sbjct: 343 TLYGPHMRFAILASIVVSQIGFSSAYISFVASTLQACVKVISTTHREYHLA---VFIFIQ 399
Query: 219 ALVILPTVWLKDLRVISYLSVGGIAATILIIISV----FSVGTTVGFHHTGRVVNWSGIP 274
LV +P L +R IS LS + A + I++ + F T+ V ++
Sbjct: 400 FLVFVP---LSLVRKISKLSATALIADVFILLGILYLYFWDVITLATKGIADVAMFNKTD 456
Query: 275 FA--IGVYGFCFAGHSVFPNIYQSMADKKQYTKALITCFVLCILIYGSVAVMGFLSFGDD 332
F+ IGV F + G + I + MA K K L L++ S+ ++ + +FG
Sbjct: 457 FSLFIGVAIFTYEGICLILPIQEQMAKPKNLPKLLTGVMAAISLLFISIGLLSYAAFGSK 516
Query: 333 TLSQITLNMPAGAF 346
+ + LNMP F
Sbjct: 517 VKTVVILNMPESTF 530
>MTR_NEUCR (P38680) N amino acid transport system protein
(Methyltryptophan resistance protein)
Length = 470
Score = 49.3 bits (116), Expect = 2e-05
Identities = 58/264 (21%), Positives = 111/264 (41%), Gaps = 32/264 (12%)
Query: 106 VGLLSTPYTVKQAGWM-GLVLMLIFASVCCYTATLMRHCFESREGLTSYPDIGEAAFGRY 164
+G LS P G + G++L + +C YTA ++ + Y D+G FGR+
Sbjct: 69 LGSLSLPGAFATLGMVPGVILSVGMGLICIYTAHVIGQTKLKHPEIAHYADVGRVMFGRW 128
Query: 165 GRIFVSIILYTELYSYCVEFITLEGDN-LTGLFPGTSLDIGGLHLDSMHLFGVLTALVI- 222
G +S + + ++ I + G + LTG ++ G S+ +FG+++A+++
Sbjct: 129 GYEIIS-------FMFVLQLIFIVGSHVLTGTIMWGTITDNGNGTCSL-VFGIVSAIILF 180
Query: 223 ---LPTVWLKDLRVISYLSVGGIAATILIIISVFSVGTTVGFHHTG--RVVNWSGIP--- 274
+P + ++ ++ Y+ I A ILI + + ++ H G V WS P
Sbjct: 181 LLAIPPSF-AEVAILGYIDFVSICAAILITMIATGIRSS---HQEGGLAAVPWSCWPKED 236
Query: 275 -------FAIGVYGFCFAGHSVFPNIYQSMADKKQYTKALITCFVLCILIYGSVAVMGFL 327
A+ F ++ + M Y K+++ ++ I IY + +
Sbjct: 237 LSLAEGFIAVSNIVFAYSFAMCQFSFMDEMHTPSDYKKSIVALGLIEIFIYTVTGGVVYA 296
Query: 328 SFGDDTLSQITLNMPAGAFASKVA 351
G + S L+ AG +KVA
Sbjct: 297 FVGPEVQSPALLS--AGPLLAKVA 318
>TYRP_HAEIN (P44727) Tyrosine-specific transport protein 1 (Tyrosine
permease 1)
Length = 400
Score = 47.0 bits (110), Expect = 7e-05
Identities = 44/180 (24%), Positives = 79/180 (43%), Gaps = 22/180 (12%)
Query: 103 MAGVGLLSTPYTVKQAGW-MGLVLMLIFASVCCYTATLMRHCFESREGLTSYPDIGEAAF 161
M G G+L+ P T G+ LVL+L ++ ++A L +++ E + E F
Sbjct: 15 MIGAGMLAMPLTSAGIGFGFTLVLLLGLWALLTFSALLFVELYQTAESDAGIGTLAEQYF 74
Query: 162 GRYGRIFVSIILYTELYSYCVEFITLEGDNLTGLFP----------------GTSLDIGG 205
G+ GRI + +L LY+ +I+ G L L P G+ + IG
Sbjct: 75 GKTGRIIATAVLIIFLYALIAAYISGGGSLLKDLLPESFGDKVSVLLFTVIFGSFIVIGT 134
Query: 206 LHLDSMH---LFGVLTALVILPTVWLKDLRVISYLSVGGIAATILIIISVFSVGTTVGFH 262
+D ++ F +L A ++ ++ L +++ + ++ A I+ VF T GFH
Sbjct: 135 HSVDKINRVLFFVMLAAFAVVLSLMLPEIKFDNLMATPIDKALIISASPVFF--TAFGFH 192
>AVT3_YEAST (P36062) Vacuolar amino acid transporter 3
Length = 692
Score = 47.0 bits (110), Expect = 7e-05
Identities = 53/253 (20%), Positives = 99/253 (38%), Gaps = 27/253 (10%)
Query: 105 GVGLLSTPYTVKQAGWMGLVLMLIFASVCCYTATLMRHCFESREGLTSYPDIGEAAFGR- 163
G G+L P GW L L+ ++ Y + + + G+ Y D+G +G
Sbjct: 312 GTGVLFLPKAFHNGGWGFSALCLLSCALISYGCFVSLITTKDKVGVDGYGDMGRILYGPK 371
Query: 164 -----YGRIFVSIILYTELYS-YCVEFITLEGDNLTGLFPGTSLDIGGLHLDSMHLFGVL 217
I +S I ++ Y+ + + + +N L PG+ S+ +
Sbjct: 372 MKFAILSSIALSQIGFSAAYTVFTATNLQVFSENFFHLKPGSI---------SLATYIFA 422
Query: 218 TALVILPTVWLKDLRVISYLSVGGIAATILIII--------SVFSVGTTVGFHHTGRVVN 269
L+ +P L R I+ LS + A + I++ S++ + T + N
Sbjct: 423 QVLIFVP---LSLTRNIAKLSGTALIADLFILLGLVYVYVYSIYYIAVNGVASDTMLMFN 479
Query: 270 WSGIPFAIGVYGFCFAGHSVFPNIYQSMADKKQYTKALITCFVLCILIYGSVAVMGFLSF 329
+ IG F F G + I +SM K + +L + +I+ S ++ + +F
Sbjct: 480 KADWSLFIGTAIFTFEGIGLLIPIQESMKHPKHFRPSLSAVMCIVAVIFISCGLLCYAAF 539
Query: 330 GDDTLSQITLNMP 342
G D + + LN P
Sbjct: 540 GSDVKTVVLLNFP 552
>YSPK_CAEEL (Q19425) Hypothetical protein F13H10.3 in chromosome IV
Length = 615
Score = 46.2 bits (108), Expect = 1e-04
Identities = 25/78 (32%), Positives = 46/78 (58%), Gaps = 7/78 (8%)
Query: 95 TVFNGINVMAGVGLLSTPYTVKQAGW-MGLVLMLIFASVCCYTATLMRHCFESREGLT-- 151
T+F+ N M G LL+ P+ ++QAG +G+++ML A++C YTA ++ + + L+
Sbjct: 168 TIFSIWNTMMGTSLLAMPWALQQAGLVLGIIIMLSMAAICFYTAYIVIESPKRLQDLSVD 227
Query: 152 ----SYPDIGEAAFGRYG 165
+ D+ ++ FGR G
Sbjct: 228 PLLAEFSDVCKSLFGRIG 245
>S383_RAT (Q9JHZ9) System N amino acid transporter 1 (SN1) (N-system
amino acid transporter 1) (Solute carrier family 38,
member 3)
Length = 504
Score = 45.4 bits (106), Expect = 2e-04
Identities = 55/290 (18%), Positives = 107/290 (35%), Gaps = 46/290 (15%)
Query: 91 SYTQTVFNGINVMAGVGLLSTPYTVKQAGWMGLVLMLIFASVCCYTATLMRHCFESREGL 150
S+ +VFN N + G G+L Y + G++L L + ++ H G+
Sbjct: 66 SFGMSVFNLSNAIMGSGILGLAYAMANT---GIILFLFLLTAVALLSSYSIHLLLKSSGI 122
Query: 151 T---SYPDIGEAAFGRYGRIFVSIILYTE---LYSYCVEFITLEGDNLTGLFPGTSLDIG 204
+Y +G AFG G++ ++ + + S + I E + F
Sbjct: 123 VGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEKPTP 182
Query: 205 GLHLDSMHLFGVLTALVILPTVWLKDLRVISYLSVGGIAATILIIISVF----------- 253
++D +L +++ ++ILP ++ L + Y S ++ + +I+V
Sbjct: 183 VWYMDGNYLVILVSVIIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFQVPCPLA 242
Query: 254 --SVGTTVGFHHTGRVVNWSGI----------------------PFAIGVYGFCFAGHSV 289
V T F H V S + + I + F F H
Sbjct: 243 HNLVNATGNFSHMVVVEEKSQLQSEPDTAEAFCTPSYFTLNSQTAYTIPIMAFAFVCHPE 302
Query: 290 FPNIYQSMADKKQYTKALITCFVLCIL--IYGSVAVMGFLSFGDDTLSQI 337
IY + D + I+ + ++ +Y A+ G+L+F D S++
Sbjct: 303 VLPIYTELKDPSKRKMQHISNLSIAVMYVMYFLAALFGYLTFYDGVESEL 352
>S383_MOUSE (Q9DCP2) System N amino acid transporter 1 (SN1)
(N-system amino acid transporter 1) (Solute carrier
family 38, member 3) (mNAT)
Length = 505
Score = 43.9 bits (102), Expect = 6e-04
Identities = 55/291 (18%), Positives = 108/291 (36%), Gaps = 47/291 (16%)
Query: 91 SYTQTVFNGINVMAGVGLLSTPYTVKQAGWMGLVLMLIFASVCCYTATLMRHCFESREGL 150
S+ +VFN N + G G+L Y + G++L L + ++ H G+
Sbjct: 66 SFGMSVFNLSNAIMGSGILGLAYAMANT---GIILFLFLLTAVALLSSYSIHLLLKSSGI 122
Query: 151 T---SYPDIGEAAFGRYGRIFVSIILYTE---LYSYCVEFITLEGDNLTGLFPGTSLDIG 204
+Y +G AFG G++ ++ + + S + I E + F
Sbjct: 123 VGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEKPAS 182
Query: 205 GLHLDSMHLFGVLTALVILPTVWLKDLRVISYLSVGGIAATILIIISV----FSVGTTVG 260
++D +L +++ +ILP ++ L + Y S ++ + +I+V F V +
Sbjct: 183 VWYMDGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFQVPCPLA 242
Query: 261 FHHTGRVVNWS------------GIP--------------------FAIGVYGFCFAGHS 288
+ N+S G P + I + F F H
Sbjct: 243 HNLANATGNFSHMVVAEEKAQLQGEPDTAAEAFCTPSYFTLNSQTAYTIPIMAFAFVCHP 302
Query: 289 VFPNIYQSMADKKQYTKALITCFVLCIL--IYGSVAVMGFLSFGDDTLSQI 337
IY + D + I+ + ++ +Y A+ G+L+F D S++
Sbjct: 303 EVLPIYTELKDPSKRKMQHISNLSIAVMYVMYFLAALFGYLTFYDGVESEL 353
>AVT6_YEAST (P40074) Vacuolar amino acid transporter 6
Length = 448
Score = 40.8 bits (94), Expect = 0.005
Identities = 43/262 (16%), Positives = 108/262 (40%), Gaps = 27/262 (10%)
Query: 100 INVMAGVGLLSTPYTVKQAGWMGLVLMLIFASVCCYTATLMRHCFESREGLTSYPDIGEA 159
++ G G+L+ PY K G + V+M++ C + + + + Y G A
Sbjct: 13 LHTACGAGILAMPYAFKPFGLIPGVIMIVLCGACAMQSLFI------QARVAKYVPQGRA 66
Query: 160 AFGRYGR-------IFVSIILYTELYSYCVEFITLEGDNLTGLFPGTSLDIGGLHLDSMH 212
+F R I + + + + V ++ + GD + + + + L+ +
Sbjct: 67 SFSALTRLINPNLGIVFDLAIAIKCFGVGVSYMIVVGDLMPQIMSVWTRNAWLLNRNVQ- 125
Query: 213 LFGVLTALVILPTVWLK---DLRVISYLSVGGIAATILIIISVFSVGTTVGFHHTGRV-- 267
++ + P +LK LR S +++ +A ++++ + + GR+
Sbjct: 126 -ISLIMLFFVAPLSFLKKLNSLRYASMVAISSVAYLCVLVLLHYVAPSDEILRLKGRISY 184
Query: 268 -----VNWSGIPFAIGVYGFCF-AGHSVFPNIYQSMADKKQYT-KALITCFVLCILIYGS 320
+ + + ++ F + H++F I + + + ++ K + L +++Y +
Sbjct: 185 LLPPQSHDLNVLNTLPIFVFAYTCHHNMFSIINEQRSSRFEHVMKIPLIAISLALILYIA 244
Query: 321 VAVMGFLSFGDDTLSQITLNMP 342
+ G+L+FGD+ + I + P
Sbjct: 245 IGCAGYLTFGDNIIGNIIMLYP 266
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.325 0.140 0.433
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,315,304
Number of Sequences: 164201
Number of extensions: 1740625
Number of successful extensions: 4920
Number of sequences better than 10.0: 39
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 4879
Number of HSP's gapped (non-prelim): 39
length of query: 359
length of database: 59,974,054
effective HSP length: 111
effective length of query: 248
effective length of database: 41,747,743
effective search space: 10353440264
effective search space used: 10353440264
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 66 (30.0 bits)
Medicago: description of AC146631.5