BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC146590.14 - phase: 1 /pseudo
(299 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ANX4_FRAAN (P51074) Annexin-like protein RJ4 177 3e-44
ANXD_CANFA (Q29471) Annexin A13 (Annexin XIII) (Annexin, intesti... 109 9e-24
ANXD_HUMAN (P27216) Annexin A13 (Annexin XIII) (Annexin, intesti... 107 3e-23
ANXB_RABIT (P33477) Annexin A11 (Annexin XI) (Calcyclin-associat... 96 1e-19
ANX3_MOUSE (O35639) Annexin A3 (Annexin III) (Lipocortin III) (P... 96 1e-19
ANX1_RABIT (P51662) Annexin A1 (Annexin I) (Lipocortin I) (Calpa... 94 3e-19
AN12_COLLI (Q92040) Annexin I, isoform P37 (Lipocortin I) (Calpa... 94 3e-19
ANXB_BOVIN (P27214) Annexin A11 (Annexin XI) (Calcyclin-associat... 94 5e-19
ANX1_BOVIN (P46193) Annexin A1 (Annexin I) (Lipocortin I) (Calpa... 94 5e-19
ANX2_CHICK (P17785) Annexin A2 (Annexin II) (Lipocortin II) (Cal... 93 7e-19
ANXB_MOUSE (P97384) Annexin A11 (Annexin XI) (Calcyclin-associat... 92 2e-18
ANXB_HUMAN (P50995) Annexin A11 (Annexin XI) (Calcyclin-associat... 92 2e-18
ANX1_CAVCU (P14087) Annexin A1 (Annexin I) (Lipocortin I) (Calpa... 92 2e-18
ANX3_RAT (P14669) Annexin A3 (Annexin III) (Lipocortin III) (Pla... 91 5e-18
ANX3_HUMAN (P12429) Annexin A3 (Annexin III) (Lipocortin III) (P... 90 8e-18
ANX2_XENLA (P24801) Annexin II type II (Lipocortin II) (Calpacti... 90 8e-18
ANX1_HORSE (Q8HZM6) Annexin A1 (Annexin I) (Lipocortin I) (Calpa... 90 8e-18
AN11_COLLI (P14950) Annexin I, isoform P35 (Lipocortin I) (Calpa... 89 1e-17
ANX1_HUMAN (P04083) Annexin A1 (Annexin I) (Lipocortin I) (Calpa... 89 1e-17
ANX1_MOUSE (P10107) Annexin A1 (Annexin I) (Lipocortin I) (Calpa... 89 2e-17
>ANX4_FRAAN (P51074) Annexin-like protein RJ4
Length = 314
Score = 177 bits (449), Expect = 3e-44
Identities = 118/309 (38%), Positives = 171/309 (55%), Gaps = 35/309 (11%)
Query: 2 GVDEKSLIAVLGKWDPLERETYRKKTSHFFIEDHERQFQRWNDHCVRLLKHEFVR-FKNA 60
G +EK++I++LG + +R+ R + ED ++ L+ E F+ A
Sbjct: 27 GTNEKAIISILGHRNAGQRKEIRAAYEQLYQED-----------LLKPLESELSGDFEKA 75
Query: 61 VVLWSMHPWERDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEED 120
V W++ P +RDA LA A+KK + Y V+IEI+C S EELL R+AY + HS+EED
Sbjct: 76 VYRWTLDPADRDAVLANVAIKKSTDVYNVIIEISCIHSPEELLAVRRAYQLRYKHSVEED 135
Query: 121 VASHIHGNDRKLLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRI 180
+A+H G+ RKLLVALV+AYRY+G ++ A SEA L +AIK+ +E+IRI
Sbjct: 136 LAAHTTGDIRKLLVALVTAYRYDGHEINAKLANSEADILHDAIKD----KAFNHEEIIRI 191
Query: 181 LATRSKLXLQAVYTAL*RDFWEES*RGIINK*TLFKE-----------TVQCLCTPQVYF 229
L+TRSK L A + D +GI L +E ++CL P+ YF
Sbjct: 192 LSTRSKTQLMATFNKYRDD------QGISISKNLLEEGANDFQKALHTAIRCLNDPKKYF 245
Query: 230 SKVLDAALKNDVNKNIKKSLTRVIVTRADIDMKEIKAEYNNLYGVSLPQKIEETAKGNYK 289
KVL A+K + +LTRVIVTRA+ D+++IK Y V L Q + + G+YK
Sbjct: 246 EKVLRNAIKRVGTD--EDALTRVIVTRAERDLRDIKEVYYKKNSVPLEQAVAKDTSGDYK 303
Query: 290 DFLLTLIAR 298
FLLTL+ +
Sbjct: 304 AFLLTLLGK 312
>ANXD_CANFA (Q29471) Annexin A13 (Annexin XIII) (Annexin,
intestine-specific) (ISA)
Length = 315
Score = 109 bits (272), Expect = 9e-24
Identities = 92/302 (30%), Positives = 149/302 (48%), Gaps = 24/302 (7%)
Query: 2 GVDEKSLIAVLGKWDPLERETYRKKTSHFFIEDHERQFQRWNDHCVRLLKHEFVRFKNAV 61
G DE ++I +L ER+ ++K + +D E F+ +D L F K A+
Sbjct: 30 GTDEAAIIEILSSRTSDERQQIKQKYKATYGKDLEEVFK--SD-----LSGNFE--KTAL 80
Query: 62 VLWSMHPWERDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEEDV 121
L P E DAR ++A+K VLIEI CTR+++E++ ++AY LFD S+E DV
Sbjct: 81 ALLD-RPSEYDARQLQKAMKGLGTDEAVLIEILCTRTNKEIMAIKEAYQRLFDRSLESDV 139
Query: 122 ASHIHGNDRKLLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRIL 181
+ GN + +LV+L+ A R EG V D A +AK L +A + +EV L
Sbjct: 140 KADTSGNLKAILVSLLQANRDEGDDVDKDLAGQDAKDLYDAGDGRWGTDELAFNEV---L 196
Query: 182 ATRSKLXLQAVYTAL-------*RDFWEES*RGIINK*TLFKETVQCLCTPQVYFSKVLD 234
A RS L+A + A + E G + K + V+C + YF+ L
Sbjct: 197 AKRSHKQLRATFQAYQILIDKDIEEAIEAETSGDLQK--AYLTLVRCARDQEGYFADRLY 254
Query: 235 AALKNDVNKNIKKSLTRVIVTRADIDMKEIKAEYNNLYGVSLPQKIEETAKGNYKDFLLT 294
++K +++L +IVTRA++D++ IKA++ Y SL + G+++ L+
Sbjct: 255 KSMKG--TGTDEETLIHIIVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFQKLLVA 312
Query: 295 LI 296
L+
Sbjct: 313 LL 314
Score = 41.6 bits (96), Expect = 0.002
Identities = 34/131 (25%), Positives = 58/131 (43%), Gaps = 15/131 (11%)
Query: 70 ERDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEEDVASHIHGND 129
+ DA+ +A K +IEI +R+S+E ++ Y + + +EE S + GN
Sbjct: 16 DHDAKKLNKACKGMGTDEAAIIEILSSRTSDERQQIKQKYKATYGKDLEEVFKSDLSGNF 75
Query: 130 RKLLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRILATRSKLXL 189
K +AL+ D ++ +A+ L A+K V +I IL TR+ +
Sbjct: 76 EKTALALL-----------DRPSEYDARQLQKAMKGLGTDEAV----LIEILCTRTNKEI 120
Query: 190 QAVYTAL*RDF 200
A+ A R F
Sbjct: 121 MAIKEAYQRLF 131
>ANXD_HUMAN (P27216) Annexin A13 (Annexin XIII) (Annexin,
intestine-specific) (ISA)
Length = 315
Score = 107 bits (268), Expect = 3e-23
Identities = 87/303 (28%), Positives = 148/303 (48%), Gaps = 26/303 (8%)
Query: 2 GVDEKSLIAVLGKWDPLERETYRKKTSHFFIEDHERQFQRWNDHCVRLLKHEFV-RFKNA 60
G +E ++I +L ER+ ++K + ++ E +LK E F+
Sbjct: 30 GTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEE-----------VLKSELSGNFEKT 78
Query: 61 VVLWSMHPWERDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEED 120
+ P E AR ++A+K VLIE CTR+++E++ ++AY LFD S+E D
Sbjct: 79 ALALLDRPSEYAARQLQKAMKGLGTDESVLIEFLCTRTNKEIIAIKEAYQRLFDRSLESD 138
Query: 121 VASHIHGNDRKLLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRI 180
V GN +K+LV+L+ A R EG V D A +AK L +A + + +EV
Sbjct: 139 VKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEV--- 195
Query: 181 LATRSKLXLQAVYTAL-------*RDFWEES*RGIINK*TLFKETVQCLCTPQVYFSKVL 233
LA RS L+A + A + EE G + K + V+C + YF++ L
Sbjct: 196 LAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQK--AYLTLVRCAQDCEDYFAERL 253
Query: 234 DAALKNDVNKNIKKSLTRVIVTRADIDMKEIKAEYNNLYGVSLPQKIEETAKGNYKDFLL 293
++K +++L R++VTRA++D++ IKA++ Y SL + G+++ L+
Sbjct: 254 YKSMKGAGTD--EETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLV 311
Query: 294 TLI 296
L+
Sbjct: 312 ALL 314
Score = 42.4 bits (98), Expect = 0.001
Identities = 42/184 (22%), Positives = 76/184 (40%), Gaps = 44/184 (23%)
Query: 70 ERDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEEDVASHIHGND 129
+RDA+ +A K + +IEI R+S+E ++ Y + + +EE + S + GN
Sbjct: 16 DRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGNF 75
Query: 130 RKLLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRILATRSKLXL 189
K +AL+ D ++ A+ L A+K ++ +I L TR+ +
Sbjct: 76 EKTALALL-----------DRPSEYAARQLQKAMKGLG----TDESVLIEFLCTRTNKEI 120
Query: 190 QAVYTAL*RDFWEES*RGIINK*TLFKETVQCLCTPQVYFSKVLDAALKNDVNKNIKKSL 249
A+ KE Q L F + L++ +K D + N+KK L
Sbjct: 121 IAI-----------------------KEAYQRL------FDRSLESDVKGDTSGNLKKIL 151
Query: 250 TRVI 253
++
Sbjct: 152 VSLL 155
>ANXB_RABIT (P33477) Annexin A11 (Annexin XI) (Calcyclin-associated
annexin 50) (CAP-50)
Length = 503
Score = 95.9 bits (237), Expect = 1e-19
Identities = 79/300 (26%), Positives = 142/300 (47%), Gaps = 22/300 (7%)
Query: 2 GVDEKSLIAVLGKWDPLERETYRKKTSHFFIEDHERQFQRWNDHCVRLLKHEFV-RFKNA 60
G DE+++I LG +R+ + +D ++ LK E F+
Sbjct: 215 GTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKD-----------LIKDLKSELSGNFEKT 263
Query: 61 VVLWSMHPWERDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEED 120
++ P DA KEA+K LIEI +RS+E + KAY + F ++EE
Sbjct: 264 ILALMKTPILFDAYEIKEAIKGAGTDEACLIEILASRSNEHIRELNKAYKTEFKKTLEEA 323
Query: 121 VASHIHGNDRKLLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRI 180
+ S G+ ++LL++L R E T V + + + L A +N+ ++ + +
Sbjct: 324 IRSDTSGHFQRLLISLSQGNRDESTNVDMSLVQRDVQELYAA---GENRLGTDESKFNAV 380
Query: 181 LATRSKLXLQAVYTAL*RDFWEES*RGIINK*TLFKE-----TVQCLCTPQVYFSKVLDA 235
L +RS+ L AV+ R + + I + + E V+CL +F++ L+
Sbjct: 381 LCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEQGMLAVVKCLKNTPAFFAERLNR 440
Query: 236 ALKNDVNKNIKKSLTRVIVTRADIDMKEIKAEYNNLYGVSLPQKIEETAKGNYKDFLLTL 295
A++ K+ ++L R++V+R++ID+ +I+AEY +YG SL I G+Y+ LL +
Sbjct: 441 AMRGAGTKD--RTLIRIMVSRSEIDLLDIRAEYKRMYGKSLYHDISGDTSGDYRKILLKI 498
Score = 32.0 bits (71), Expect = 1.9
Identities = 40/206 (19%), Positives = 84/206 (40%), Gaps = 48/206 (23%)
Query: 71 RDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEEDVASHIHGNDR 130
RDA + ++A+K +I+ +RS+++ ++ + + + +D+ S + GN
Sbjct: 202 RDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFE 261
Query: 131 KLLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRILATRSKLXLQ 190
K ++AL+ T + D A + AIK A ++ +I ILA+RS ++
Sbjct: 262 KTILALMK------TPILFD-----AYEIKEAIKGAG----TDEACLIEILASRSNEHIR 306
Query: 191 AVYTAL*RDFWEES*RGIINK*TLFKETVQCLCTPQVYFSKVLDAALKNDVNKNIKKSLT 250
+ A + F K L+ A+++D + + ++ L
Sbjct: 307 ELNKAY-----------------------------KTEFKKTLEEAIRSDTSGHFQRLLI 337
Query: 251 RVIVTRAD----IDMKEIKAEYNNLY 272
+ D +DM ++ + LY
Sbjct: 338 SLSQGNRDESTNVDMSLVQRDVQELY 363
>ANX3_MOUSE (O35639) Annexin A3 (Annexin III) (Lipocortin III)
(Placental anticoagulant protein III) (PAP-III)
(35-alpha calcimedin)
Length = 323
Score = 95.5 bits (236), Expect = 1e-19
Identities = 83/299 (27%), Positives = 146/299 (48%), Gaps = 20/299 (6%)
Query: 2 GVDEKSLIAVLGKWDPLERETYRKKTSHFFIEDHERQFQRWNDHCVRLLKHEFVRFKNAV 61
G DEK+LI +L + +R+ K+ + +E++ + +D L H F++ +
Sbjct: 35 GTDEKTLINILTERSNAQRQLIVKQ----YQAAYEQELK--DDLKGDLSGH----FEHVM 84
Query: 62 VLWSMHPWERDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEEDV 121
V P DA K+++K LIEI TRSS ++ +AY++++ S+ +D+
Sbjct: 85 VALVTAPALFDANELKKSMKGTGTDEDALIEILTTRSSRQMKEISQAYYTVYKKSLGDDI 144
Query: 122 ASHIHGNDRKLLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRIL 181
+S G+ RK L+ L R E KV + AK +A+ L NA +NK ++D+ +L
Sbjct: 145 SSETSGDFRKALLTLADGRRDESLKVDEHLAKKDAQILYNA---GENKWGTDEDKFTEVL 201
Query: 182 ATRSKLXLQAV---YTAL*RDFWEES*RGIINK--*TLFKETVQCLCTPQVYFSKVLDAA 236
RS L+ Y + + E+S +G ++ L V C + ++ L A
Sbjct: 202 CLRSFPQLKLTFDEYRNISQKDIEDSIKGELSGHFEDLLLAIVHCARNTPAFLAERLHQA 261
Query: 237 LKNDVNKNIKKSLTRVIVTRADIDMKEIKAEYNNLYGVSLPQKIEETAKGNYKDFLLTL 295
LK +L R++V+R++ID+ +I+ E+ YG SL I+ G+Y+ LL +
Sbjct: 262 LKGAGTDEF--TLNRIMVSRSEIDLLDIRHEFKKHYGYSLYSAIQSDTSGDYRTVLLKI 318
Score = 41.6 bits (96), Expect = 0.002
Identities = 55/242 (22%), Positives = 100/242 (40%), Gaps = 37/242 (15%)
Query: 72 DARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEEDVASHIHGNDRK 131
DA ++A++ LI I RS+ + K Y + ++ +++D+ + G+
Sbjct: 23 DAEAIRKAIRGLGTDEKTLINILTERSNAQRQLIVKQYQAAYEQELKDDLKGDLSGHFEH 82
Query: 132 LLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRILATRS----KL 187
++VALV+A A +N +K + ++D +I IL TRS K
Sbjct: 83 VMVALVTA---------------PALFDANELKKSMKGTGTDEDALIEILTTRSSRQMKE 127
Query: 188 XLQAVYTAL*RDFWEES*RGIINK*TL--FKETVQCLCTPQVYFSKVLDAAL-KNDV--- 241
QA YT + ++ I+ T F++ + L + S +D L K D
Sbjct: 128 ISQAYYTVYKKSLGDD-----ISSETSGDFRKALLTLADGRRDESLKVDEHLAKKDAQIL 182
Query: 242 -----NK--NIKKSLTRVIVTRADIDMKEIKAEYNNLYGVSLPQKIEETAKGNYKDFLLT 294
NK + T V+ R+ +K EY N+ + I+ G+++D LL
Sbjct: 183 YNAGENKWGTDEDKFTEVLCLRSFPQLKLTFDEYRNISQKDIEDSIKGELSGHFEDLLLA 242
Query: 295 LI 296
++
Sbjct: 243 IV 244
>ANX1_RABIT (P51662) Annexin A1 (Annexin I) (Lipocortin I)
(Calpactin II) (Chromobindin 9) (P35) (Phospholipase A2
inhibitory protein)
Length = 346
Score = 94.4 bits (233), Expect = 3e-19
Identities = 82/302 (27%), Positives = 142/302 (46%), Gaps = 26/302 (8%)
Query: 2 GVDEKSLIAVLGKWDPLERETYRKKTSHFFIEDHERQFQRWNDHCVRLLKHEFVRFKNAV 61
GVDE ++I +L K + +R+ + ++++ + +LK V
Sbjct: 59 GVDEATIIDILTKRNNAQRQQIKAA----YLQEKGKPLDE-------VLKKALTGHLEEV 107
Query: 62 VLWSMH-PWERDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEED 120
VL + P + DA + A+K LIEI +R+++E+ + Y + +D
Sbjct: 108 VLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRNNKEIREINRVYREELKRDLAKD 167
Query: 121 VASHIHGNDRKLLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRI 180
+AS G+ +K L++L R E V +D A ++A+ L A + + + + I
Sbjct: 168 IASDTSGDFQKALLSLAKGDRSEDFGVNEDLADTDARALYEAGERRKGADV---NVFTTI 224
Query: 181 LATRSKLXLQAVYTAL*RDFWEE-------S*RGIINK*TLFKETVQCLCTPQVYFSKVL 233
L TRS L L+ V+ + + +G I K VQC YF++ L
Sbjct: 225 LTTRSYLHLRRVFQKYSKYSQHDMNKVLDLELKGDIEK--CLTAIVQCATCKPAYFAEKL 282
Query: 234 DAALKNDVNKNIKKSLTRVIVTRADIDMKEIKAEYNNLYGVSLPQKIEETAKGNYKDFLL 293
A+K ++ K+L R++V+R+++DM +IKA Y YGVSL Q I + KG+Y+ L+
Sbjct: 283 YQAMKGAGTRH--KALIRIMVSRSEVDMNDIKAFYQKKYGVSLCQAILDETKGDYEKILV 340
Query: 294 TL 295
L
Sbjct: 341 AL 342
>AN12_COLLI (Q92040) Annexin I, isoform P37 (Lipocortin I)
(Calpactin II) (Chromobindin 9) (Phospholipase A2
inhibitory protein)
Length = 343
Score = 94.4 bits (233), Expect = 3e-19
Identities = 80/301 (26%), Positives = 141/301 (46%), Gaps = 24/301 (7%)
Query: 2 GVDEKSLIAVLGKWDPLERETYRKKTSHFFIEDHERQFQRWNDHCVRLLKHEFVRFKNAV 61
GVDE ++I ++ K +R +R K ++ + + + + R+LK ++ V
Sbjct: 55 GVDEATIIDIMTKRTNAQR--HRIKAAY-----QKAKGKSLEEAMKRVLKSHL---EDVV 104
Query: 62 VLWSMHPWERDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEEDV 121
V P + DA + +K LIEI +RS++E+ A + Y + + +D+
Sbjct: 105 VALLKTPAQFDAEELRACMKGLGTDEDTLIEILASRSNKEIREASRYYKEVLKRDLTQDI 164
Query: 122 ASHIHGNDRKLLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRIL 181
S G+ +K LV L R E V DD A ++A+ L A + K + + + +L
Sbjct: 165 ISDTSGHFQKALVVLAKGDRCEDPHVNDDLADNDARALYEA---GEQKKGTDVNVFVTVL 221
Query: 182 ATRSKLXLQAVYTAL*R-------DFWEES*RGIINK*TLFKETVQCLCTPQVYFSKVLD 234
RS L+ V+ + + +G I K V+C + +F++ L
Sbjct: 222 TARSYPHLRRVFQKYTKYSKHDMNKVVDMELKGDIEK--CLTALVKCATSKPAFFAEKLH 279
Query: 235 AALKNDVNKNIKKSLTRVIVTRADIDMKEIKAEYNNLYGVSLPQKIEETAKGNYKDFLLT 294
A+K ++ K L R++V+R ++DM EIK Y +YG+SL Q I + KG+Y+ L+
Sbjct: 280 LAMKGFGTRH--KDLIRIMVSRHEVDMNEIKCYYKKMYGISLCQAIMDDLKGDYETILVA 337
Query: 295 L 295
L
Sbjct: 338 L 338
>ANXB_BOVIN (P27214) Annexin A11 (Annexin XI) (Calcyclin-associated
annexin 50) (CAP-50)
Length = 503
Score = 93.6 bits (231), Expect = 5e-19
Identities = 79/300 (26%), Positives = 141/300 (46%), Gaps = 22/300 (7%)
Query: 2 GVDEKSLIAVLGKWDPLERETYRKKTSHFFIEDHERQFQRWNDHCVRLLKHEFV-RFKNA 60
G DE+++I LG +R+ + +D ++ LK E F+
Sbjct: 215 GTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKD-----------LIKDLKSELSGNFEKT 263
Query: 61 VVLWSMHPWERDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEED 120
++ P DA KEA+K LIEI +RS+E + + Y + F ++EE
Sbjct: 264 ILALMKTPVLFDAYEIKEAIKGAGTDEACLIEILASRSNEHIRELNRVYKTEFKKTLEEA 323
Query: 121 VASHIHGNDRKLLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRI 180
+ S G+ ++LL++L R E T V + + + L A +N+ ++ + I
Sbjct: 324 IRSDTSGHFQRLLISLSQGNRDESTNVDMTLVQRDVQELYAA---GENRLGTDESKFNAI 380
Query: 181 LATRSKLXLQAVYTAL*RDFWEES*RGIINK*TLFKE-----TVQCLCTPQVYFSKVLDA 235
L +RS+ L AV+ R + + I + + E V+CL +F++ L+
Sbjct: 381 LCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEQGMLAVVKCLKNTPAFFAERLNK 440
Query: 236 ALKNDVNKNIKKSLTRVIVTRADIDMKEIKAEYNNLYGVSLPQKIEETAKGNYKDFLLTL 295
A++ K+ ++L R++V+R++ID+ +I+AEY LYG SL I G+Y+ LL +
Sbjct: 441 AMRGAGTKD--RTLIRIMVSRSEIDLLDIRAEYKRLYGKSLYHDITGDTSGDYRKILLKI 498
Score = 31.2 bits (69), Expect = 3.2
Identities = 29/115 (25%), Positives = 55/115 (47%), Gaps = 15/115 (13%)
Query: 71 RDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEEDVASHIHGNDR 130
RDA + ++A+K +I+ +RS+++ ++ + + + +D+ S + GN
Sbjct: 202 RDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFE 261
Query: 131 KLLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRILATRS 185
K ++AL+ T V D A + AIK A ++ +I ILA+RS
Sbjct: 262 KTILALMK------TPVLFD-----AYEIKEAIKGAG----TDEACLIEILASRS 301
>ANX1_BOVIN (P46193) Annexin A1 (Annexin I) (Lipocortin I)
(Calpactin II) (Chromobindin 9) (P35) (Phospholipase A2
inhibitory protein)
Length = 346
Score = 93.6 bits (231), Expect = 5e-19
Identities = 82/305 (26%), Positives = 143/305 (46%), Gaps = 26/305 (8%)
Query: 2 GVDEKSLIAVLGKWDPLERETYRKKTSHFFIEDHERQFQRWNDHCVRLLKHEFVRFKNAV 61
GVDE ++I +L K + +R+ + ++++ + +LK + V
Sbjct: 59 GVDEATIIEILTKRNNAQRQQIKAA----YLQEKGKPLDE-------VLKKALLGHLEEV 107
Query: 62 VLWSMH-PWERDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEED 120
VL + P + DA + A+K L EI +R++ E+ + + + +D
Sbjct: 108 VLALLKTPAQFDAEELRAAMKGLGTDEDTLNEILASRTNREIREINRVHREELKRDLAKD 167
Query: 121 VASHIHGNDRKLLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRI 180
+AS G+ K L+AL R E V DD A S+A+ L A + + + + I
Sbjct: 168 IASDTSGDYEKALLALAKGDRSEELAVNDDLADSDARALYEAGERRKGTDV---NVFTTI 224
Query: 181 LATRSKLXLQAVYTAL*R-------DFWEES*RGIINK*TLFKETVQCLCTPQVYFSKVL 233
L TRS L+ V+ + + +G I K V+C + ++F++ L
Sbjct: 225 LTTRSYPHLRRVFQKYSKYSKHDMNKVLDLELKGDIEK--CLTVIVKCATSQPMFFAEKL 282
Query: 234 DAALKNDVNKNIKKSLTRVIVTRADIDMKEIKAEYNNLYGVSLPQKIEETAKGNYKDFLL 293
A+K ++ K+L R++V+R++IDM +IKA Y LYG+SL Q I + KG+Y+ L+
Sbjct: 283 HQAMKGIGTRH--KTLIRIMVSRSEIDMNDIKACYQKLYGISLCQAILDETKGDYEKILV 340
Query: 294 TLIAR 298
L R
Sbjct: 341 ALCGR 345
>ANX2_CHICK (P17785) Annexin A2 (Annexin II) (Lipocortin II)
(Calpactin I heavy chain) (Chromobindin 8) (P36)
(Protein I) (Placental anticoagulant protein IV)
(PAP-IV)
Length = 338
Score = 93.2 bits (230), Expect = 7e-19
Identities = 86/301 (28%), Positives = 141/301 (46%), Gaps = 23/301 (7%)
Query: 2 GVDEKSLIAVLGKWDPLERETYRKKTSHFFIEDHERQFQRWNDHCVRLLKHEFVRFKNAV 61
GVDE ++I +L R +++ F + +R LK AV
Sbjct: 49 GVDEVTIINIL-----TNRSNEQRQDIAFAYQ------RRTKKELSAALKSALSGHLEAV 97
Query: 62 VLWSMH-PWERDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEED 120
+L + P + DA K A+K LIEI C+R+++EL + Y ++ +E+D
Sbjct: 98 ILGLLKTPSQYDASELKAAMKGLGTDEDTLIEIICSRTNQELNEINRVYREMYKTELEKD 157
Query: 121 VASHIHGNDRKLLVALVSAYRYEGTKVKD-DTAKSEAKTLSNAIKNAQNKPIVEDDEVIR 179
+ S G+ RKL+VAL R E T V D + +A+ L +A + + + I
Sbjct: 158 IISDTSGDFRKLMVALAKGKRCEDTSVIDYELIDQDARELYDAGVKRKGTDV---PKWIN 214
Query: 180 ILATRSKLXLQAVYTAL*R----DFWEES*RGII-NK*TLFKETVQCLCTPQVYFSKVLD 234
I+ RS LQ V+ D E + + + F VQC+ Q+YF+ L
Sbjct: 215 IMTERSVPHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQNKQLYFADRLY 274
Query: 235 AALKNDVNKNIKKSLTRVIVTRADIDMKEIKAEYNNLYGVSLPQKIEETAKGNYKDFLLT 294
++K ++ K L R++V+R ++DM +IK+E+ YG SL I++ KG+Y+ LL
Sbjct: 275 DSMKGKGTRD--KVLIRIMVSRCEVDMLKIKSEFKRKYGKSLYYFIQQDTKGDYQRALLN 332
Query: 295 L 295
L
Sbjct: 333 L 333
>ANXB_MOUSE (P97384) Annexin A11 (Annexin XI) (Calcyclin-associated
annexin 50) (CAP-50)
Length = 503
Score = 92.0 bits (227), Expect = 2e-18
Identities = 77/300 (25%), Positives = 141/300 (46%), Gaps = 22/300 (7%)
Query: 2 GVDEKSLIAVLGKWDPLERETYRKKTSHFFIEDHERQFQRWNDHCVRLLKHEFV-RFKNA 60
G DE+++I LG +R+ + +D ++ LK E F+
Sbjct: 215 GTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKD-----------LIKDLKSELSGNFEKT 263
Query: 61 VVLWSMHPWERDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEED 120
++ P D KEA+K LIEI +RS+E + +AY + F ++EE
Sbjct: 264 ILALMKTPVLFDVYEIKEAIKGAGTDEACLIEIFASRSNEHIRELSRAYKTEFQKTLEEA 323
Query: 121 VASHIHGNDRKLLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRI 180
+ S G+ ++LL++L R E T V + + + L A +N+ ++ + I
Sbjct: 324 IRSDTSGHFQRLLISLSQGNRDESTNVDMSLVQRDVQELYAA---GENRLGTDESKFNAI 380
Query: 181 LATRSKLXLQAVYTAL*RDFWEES*RGIINK*TLFKE-----TVQCLCTPQVYFSKVLDA 235
L +RS+ L AV+ R + + I + + E V+CL +F++ L+
Sbjct: 381 LCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEQGMLAVVKCLKNTPAFFAERLNK 440
Query: 236 ALKNDVNKNIKKSLTRVIVTRADIDMKEIKAEYNNLYGVSLPQKIEETAKGNYKDFLLTL 295
A++ K+ ++L R++V+R+++D+ +I+AEY +YG SL I G+Y+ LL +
Sbjct: 441 AMRGAGTKD--RTLIRIMVSRSELDLLDIRAEYKRMYGKSLYHDITGDTSGDYRKILLKI 498
Score = 30.0 bits (66), Expect = 7.2
Identities = 39/206 (18%), Positives = 83/206 (39%), Gaps = 48/206 (23%)
Query: 71 RDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEEDVASHIHGNDR 130
RDA + ++A+K +I+ +RS+++ ++ + + + +D+ S + GN
Sbjct: 202 RDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFE 261
Query: 131 KLLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRILATRSKLXLQ 190
K ++AL+ T V D + + AIK A ++ +I I A+RS ++
Sbjct: 262 KTILALMK------TPVLFDVYE-----IKEAIKGAG----TDEACLIEIFASRSNEHIR 306
Query: 191 AVYTAL*RDFWEES*RGIINK*TLFKETVQCLCTPQVYFSKVLDAALKNDVNKNIKKSLT 250
+ A + F K L+ A+++D + + ++ L
Sbjct: 307 ELSRAY-----------------------------KTEFQKTLEEAIRSDTSGHFQRLLI 337
Query: 251 RVIVTRAD----IDMKEIKAEYNNLY 272
+ D +DM ++ + LY
Sbjct: 338 SLSQGNRDESTNVDMSLVQRDVQELY 363
>ANXB_HUMAN (P50995) Annexin A11 (Annexin XI) (Calcyclin-associated
annexin 50) (CAP-50) (56 kDa autoantigen)
Length = 505
Score = 91.7 bits (226), Expect = 2e-18
Identities = 77/300 (25%), Positives = 142/300 (46%), Gaps = 22/300 (7%)
Query: 2 GVDEKSLIAVLGKWDPLERETYRKKTSHFFIEDHERQFQRWNDHCVRLLKHEFV-RFKNA 60
G DE+++I LG +R+ + +D ++ LK E F+
Sbjct: 217 GTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKD-----------LIKDLKSELSGNFEKT 265
Query: 61 VVLWSMHPWERDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEED 120
++ P D KEA+K LIEI +RS+E + +AY + F ++EE
Sbjct: 266 ILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEA 325
Query: 121 VASHIHGNDRKLLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRI 180
+ S G+ ++LL++L R E T V A+ +A+ L A +N+ ++ + +
Sbjct: 326 IRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAA---GENRLGTDESKFNAV 382
Query: 181 LATRSKLXLQAVYTAL*RDFWEES*RGIINK*TLFKE-----TVQCLCTPQVYFSKVLDA 235
L +RS+ L AV+ R + + I + + E V+CL +F++ L+
Sbjct: 383 LCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNK 442
Query: 236 ALKNDVNKNIKKSLTRVIVTRADIDMKEIKAEYNNLYGVSLPQKIEETAKGNYKDFLLTL 295
A++ K+ ++L R++V+R++ D+ +I++EY +YG SL I G+Y+ LL +
Sbjct: 443 AMRGAGTKD--RTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKI 500
>ANX1_CAVCU (P14087) Annexin A1 (Annexin I) (Lipocortin I)
(Calpactin II) (Chromobindin 9) (P35) (Phospholipase A2
inhibitory protein) (Lipocortin-like 33 kDa protein)
Length = 346
Score = 91.7 bits (226), Expect = 2e-18
Identities = 77/300 (25%), Positives = 138/300 (45%), Gaps = 22/300 (7%)
Query: 2 GVDEKSLIAVLGKWDPLERETYRKKTSHFFIEDHERQFQRWNDHCVRLLKHEFVRFKNAV 61
GVDE ++I +L K + +R+ + ++++ + LK V
Sbjct: 59 GVDEATIIDILTKRNNAQRQQIKAA----YLQEKGKPLDE-------ALKKALTGHLEEV 107
Query: 62 VLWSMH-PWERDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEED 120
VL + P + DA + A+K LIEI +R + E+ + Y + +D
Sbjct: 108 VLALLKTPAQLDADELRAAMKGLGTDEDTLIEILVSRKNREIKEINRVYRDELKRDLAKD 167
Query: 121 VASHIHGNDRKLLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRI 180
+ S G+ +K L++L R E V DD A S+A+ L A + + + + I I
Sbjct: 168 ITSDTSGDFQKALLSLAKGDRCEDLSVNDDLADSDARALYEAGERRKGTDV---NVFITI 224
Query: 181 LATRSKLXLQAVYTAL*RDFWEES*RGIINK*-----TLFKETVQCLCTPQVYFSKVLDA 235
L TRS L+ V+ + + + + + V+C + +F++ L
Sbjct: 225 LTTRSYSHLRRVFQKYTKYSQHDMNKALDLELKGDIENCLTAIVKCATSTPAFFAEKLHL 284
Query: 236 ALKNDVNKNIKKSLTRVIVTRADIDMKEIKAEYNNLYGVSLPQKIEETAKGNYKDFLLTL 295
A+K ++ K+L R++V+R++IDM +IK Y +YG+SL Q I + KG+Y+ L+ L
Sbjct: 285 AMKGAGTRH--KALIRIMVSRSEIDMNDIKVYYQKMYGISLCQAILDETKGDYEKILVAL 342
>ANX3_RAT (P14669) Annexin A3 (Annexin III) (Lipocortin III)
(Placental anticoagulant protein III) (PAP-III)
(35-alpha calcimedin)
Length = 324
Score = 90.5 bits (223), Expect = 5e-18
Identities = 81/299 (27%), Positives = 143/299 (47%), Gaps = 20/299 (6%)
Query: 2 GVDEKSLIAVLGKWDPLERETYRKKTSHFFIEDHERQFQRWNDHCVRLLKHEFVRFKNAV 61
G DEK+LI +L + +R+ K E +E+ + D L H F++ +
Sbjct: 36 GTDEKTLINILTERSNAQRQLIVKHIQ----EAYEQALKA--DLKGDLSGH----FEHVM 85
Query: 62 VLWSMHPWERDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEEDV 121
V P DA+ K++++ LIEI TR+S ++ +AY++ + ++ +D+
Sbjct: 86 VALITAPAVFDAKQLKKSMRGMGTDEDTLIEILTTRTSRQMKEISQAYYTAYKKNLRDDI 145
Query: 122 ASHIHGNDRKLLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRIL 181
+S G+ RK L+ L R E KV + AK +A+TL +A + K ++D+ IL
Sbjct: 146 SSETSGDFRKALLTLADGGRDESLKVDEHLAKKDAQTLYDA---GEKKWGTDEDKFTEIL 202
Query: 182 ATRSKLXLQAV---YTAL*RDFWEES*RGIINK--*TLFKETVQCLCTPQVYFSKVLDAA 236
RS L+ Y + + E+S +G ++ L V+C + + L A
Sbjct: 203 CLRSFPQLKLTFDEYRNISQKDIEDSIKGELSGHFEDLLLAVVRCTRNTPAFLAGRLHQA 262
Query: 237 LKNDVNKNIKKSLTRVIVTRADIDMKEIKAEYNNLYGVSLPQKIEETAKGNYKDFLLTL 295
LK +L R++V+R++ID+ +I+ E+ YG SL I+ G+Y+ LL +
Sbjct: 263 LKGAGTDEF--TLNRIMVSRSEIDLLDIRREFKKHYGCSLYSAIQSDTSGDYRTVLLKI 319
Score = 33.9 bits (76), Expect = 0.50
Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 2/81 (2%)
Query: 219 VQCLCTPQVYFSKVLDAALKNDVNKNIKKSLTRVIVTRADIDMKEIKAEYNNLYGVSLPQ 278
V + P V+ +K L +++ + +L ++ TR MKEI Y Y +L
Sbjct: 86 VALITAPAVFDAKQLKKSMRGMGTD--EDTLIEILTTRTSRQMKEISQAYYTAYKKNLRD 143
Query: 279 KIEETAKGNYKDFLLTLIARG 299
I G+++ LLTL G
Sbjct: 144 DISSETSGDFRKALLTLADGG 164
>ANX3_HUMAN (P12429) Annexin A3 (Annexin III) (Lipocortin III)
(Placental anticoagulant protein III) (PAP-III)
(35-alpha calcimedin) (Inositol 1,2-cyclic phosphate
2-phosphohydrolase)
Length = 323
Score = 89.7 bits (221), Expect = 8e-18
Identities = 78/303 (25%), Positives = 144/303 (46%), Gaps = 28/303 (9%)
Query: 2 GVDEKSLIAVLGKWDPLERETYRKKTSHFFIEDHERQFQRWNDHCVRLLKHEFVRFKNAV 61
G DEK LI++L + +R+ K+ + ++ + +D L H F++ +
Sbjct: 35 GTDEKMLISILTERSNAQRQLIVKEYQAAYGKELK------DDLKGDLSGH----FEHLM 84
Query: 62 VLWSMHPWERDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEEDV 121
V P DA+ K+++K + LIEI TR+S ++ +AY++++ S+ +D+
Sbjct: 85 VALVTPPAVFDAKQLKKSMKGAGTNEDALIEILTTRTSRQMKDISQAYYTVYKKSLGDDI 144
Query: 122 ASHIHGNDRKLLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRIL 181
+S G+ RK L+ L R E KV + AK +A+ L K +N+ ++D+ IL
Sbjct: 145 SSETSGDFRKALLTLADGRRDESLKVDEHLAKQDAQIL---YKAGENRWGTDEDKFTEIL 201
Query: 182 ATRSKLXLQAVYTAL*RDFWEES*RGIINK---------*TLFKETVQCLCTPQVYFSKV 232
RS L+ + ++ S + I++ L V C+ + ++
Sbjct: 202 CLRSFPQLKLTFD----EYRNISQKDIVDSIKGELSGHFEDLLLAIVNCVRNTPAFLAER 257
Query: 233 LDAALKNDVNKNIKKSLTRVIVTRADIDMKEIKAEYNNLYGVSLPQKIEETAKGNYKDFL 292
L ALK +L R++V+R++ID+ +I+ E+ YG SL I+ G+Y+ L
Sbjct: 258 LHRALKGIGTDEF--TLNRIMVSRSEIDLLDIRTEFKKHYGYSLYSAIKSDTSGDYEITL 315
Query: 293 LTL 295
L +
Sbjct: 316 LKI 318
Score = 40.4 bits (93), Expect = 0.005
Identities = 52/242 (21%), Positives = 100/242 (40%), Gaps = 37/242 (15%)
Query: 72 DARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEEDVASHIHGNDRK 131
DA ++A++ +LI I RS+ + K Y + + +++D+ + G+
Sbjct: 23 DAEAIQKAIRGIGTDEKMLISILTERSNAQRQLIVKEYQAAYGKELKDDLKGDLSGHFEH 82
Query: 132 LLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRILATRSKLXL-- 189
L+VALV+ A +AK L ++K A +D +I IL TR+ +
Sbjct: 83 LMVALVT-----------PPAVFDAKQLKKSMKGAG----TNEDALIEILTTRTSRQMKD 127
Query: 190 --QAVYTAL*RDFWEES*RGIINK*TL--FKETVQCLCTPQVYFSKVLDAALKNDVNKNI 245
QA YT + ++ I+ T F++ + L + S +D L + +
Sbjct: 128 ISQAYYTVYKKSLGDD-----ISSETSGDFRKALLTLADGRRDESLKVDEHLAKQDAQIL 182
Query: 246 KKS-----------LTRVIVTRADIDMKEIKAEYNNLYGVSLPQKIEETAKGNYKDFLLT 294
K+ T ++ R+ +K EY N+ + I+ G+++D LL
Sbjct: 183 YKAGENRWGTDEDKFTEILCLRSFPQLKLTFDEYRNISQKDIVDSIKGELSGHFEDLLLA 242
Query: 295 LI 296
++
Sbjct: 243 IV 244
>ANX2_XENLA (P24801) Annexin II type II (Lipocortin II) (Calpactin I
heavy chain) (Chromobindin 8) (P36) (Protein I)
(Placental anticoagulant protein IV) (PAP-IV)
Length = 339
Score = 89.7 bits (221), Expect = 8e-18
Identities = 74/230 (32%), Positives = 114/230 (49%), Gaps = 11/230 (4%)
Query: 72 DARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEEDVASHIHGNDRK 131
DA K ++K LIEI C+R+++ELL + AY LF +E+D+ S G+ RK
Sbjct: 110 DASELKASMKGLGTDEDTLIEIICSRTNKELLDIQNAYRELFKTELEKDIMSDTSGDFRK 169
Query: 132 LLVALVSAYRYE-GTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRILATRSKLXLQ 190
L+VAL R E G V + +A+ L A + + + I I+ RS LQ
Sbjct: 170 LMVALAKGRRQEDGNMVDYEKIDQDARELYEAGVKRKGTDVT---KWITIMTERSHPHLQ 226
Query: 191 AV---YTAL*RDFWEES*RGII--NK*TLFKETVQCLCTPQVYFSKVLDAALKNDVNKNI 245
V Y + EES + + + F VQC+ +YF+ L ++K K+
Sbjct: 227 KVFERYKSYSPYDIEESIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYESMKGKGTKD- 285
Query: 246 KKSLTRVIVTRADIDMKEIKAEYNNLYGVSLPQKIEETAKGNYKDFLLTL 295
K L R++V+R ++DM +I+ E+ YG SL I + KG+Y+ LL L
Sbjct: 286 -KILIRIMVSRRNLDMLKIRQEFKKKYGKSLHYFIGQDTKGDYQRALLNL 334
Score = 30.4 bits (67), Expect = 5.5
Identities = 24/115 (20%), Positives = 50/115 (42%), Gaps = 3/115 (2%)
Query: 70 ERDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEEDVASHIHGND 129
E+DA + A+K + +I I RS+E+ A+H + + + GN
Sbjct: 36 EKDAAAIETAIKTKGVDELTIINILTNRSNEQRQDIAFAFHRRTKKDLPSALKGALSGNL 95
Query: 130 RKLLVALVSAY-RYEGTKVKDDT--AKSEAKTLSNAIKNAQNKPIVEDDEVIRIL 181
+++ L+ +Y+ +++K ++ TL I + NK +++ R L
Sbjct: 96 ETVMLGLIKTRPQYDASELKASMKGLGTDEDTLIEIICSRTNKELLDIQNAYREL 150
>ANX1_HORSE (Q8HZM6) Annexin A1 (Annexin I) (Lipocortin I)
(Calpactin II)
Length = 345
Score = 89.7 bits (221), Expect = 8e-18
Identities = 78/307 (25%), Positives = 141/307 (45%), Gaps = 30/307 (9%)
Query: 2 GVDEKSLIAVLGKWDPLERETYRKKTSHFFIEDHERQFQRWNDHCVRLLKHEFVRFKNAV 61
GVDE ++I +L K + +R+ + ++++ + L K ++
Sbjct: 58 GVDEATIIEILTKRNNAQRQQIKAA----YLQEKGKPLDE------ALKKALTGHLEDVA 107
Query: 62 VLWSMHPWERDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEEDV 121
+ P DA + A+K LIEI +R+++E+ + Y + +D+
Sbjct: 108 LALLKTPARFDADELRAAMKGLGTDEDTLIEILTSRTNKEIREINRVYREELKRDLAKDI 167
Query: 122 ASHIHGNDRKLLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRIL 181
S G+ +K L++L R E V DD A S+A+ L A + + + + IL
Sbjct: 168 TSDTSGDFQKALLSLAKGDRSEDFGVNDDLADSDARALYEAGERRKGTDV---NVFNTIL 224
Query: 182 ATRSKLXLQAVYTAL*RDFWEES*RGIINK*----------TLFKETVQCLCTPQVYFSK 231
TRS L+ V+ + + + +NK F V+C + ++F++
Sbjct: 225 TTRSYPHLRRVF-----QMYTKYSKHDMNKVLDLEMKGDVENCFTAIVKCATSKPMFFAE 279
Query: 232 VLDAALKNDVNKNIKKSLTRVIVTRADIDMKEIKAEYNNLYGVSLPQKIEETAKGNYKDF 291
L A+K ++ K L R++V+R+++DM +IKA Y LYG+SL Q I + KG+Y+
Sbjct: 280 KLHNAMKGAGTRD--KILIRIMVSRSEVDMNDIKACYQKLYGISLCQAILDETKGDYEKI 337
Query: 292 LLTLIAR 298
L+ L R
Sbjct: 338 LVALCGR 344
>AN11_COLLI (P14950) Annexin I, isoform P35 (Lipocortin I)
(Calpactin II) (Chromobindin 9) (Phospholipase A2
inhibitory protein)
Length = 341
Score = 89.4 bits (220), Expect = 1e-17
Identities = 78/300 (26%), Positives = 141/300 (47%), Gaps = 23/300 (7%)
Query: 2 GVDEKSLIAVLGKWDPLERETYRKKTSHFFIEDHERQFQRWNDHCVRLLKHEFVRFKNAV 61
GVDE ++I ++ +R R K ++ H+ + + + R+LK ++ V
Sbjct: 54 GVDEATIIDIMTTRTNAQRP--RIKAAY-----HKAKGKSLEEAMKRVLKSHL---EDVV 103
Query: 62 VLWSMHPWERDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEEDV 121
V P + DA + +K LIEI +R+++E+ A + Y + + +D+
Sbjct: 104 VALLKTPAQFDAEELRACMKGHGTDEDTLIEILASRNNKEIREACRYYKEVLKRDLTQDI 163
Query: 122 ASHIHGNDRKLLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRIL 181
S G+ +K LV+L A R E V D+ A+ +A+ L A + K + + + +L
Sbjct: 164 ISDTSGDFQKALVSLAKADRCENPHVNDELAEKDARALYEA---GEQKKGTDINVFVTVL 220
Query: 182 ATRSKLXLQAV--YTAL*RDFWEES----*RGIINK*TLFKETVQCLCTPQVYFSKVLDA 235
RS + YT + ++ +G I K V+C + +F++ L
Sbjct: 221 TARSYPHSEVFQKYTKYSKHDMNKAVDMEMKGDIEK--CLTALVKCATSKPAFFAEKLHM 278
Query: 236 ALKNDVNKNIKKSLTRVIVTRADIDMKEIKAEYNNLYGVSLPQKIEETAKGNYKDFLLTL 295
A+K ++ + L R++V+R ++DM EIK Y +YG+SL Q I + KG Y+ L+ L
Sbjct: 279 AMKGFGTQH--RDLIRIMVSRHEVDMNEIKGYYKKMYGISLCQAIMDELKGGYETILVAL 336
>ANX1_HUMAN (P04083) Annexin A1 (Annexin I) (Lipocortin I)
(Calpactin II) (Chromobindin 9) (P35) (Phospholipase A2
inhibitory protein)
Length = 345
Score = 89.0 bits (219), Expect = 1e-17
Identities = 80/302 (26%), Positives = 136/302 (44%), Gaps = 26/302 (8%)
Query: 2 GVDEKSLIAVLGKWDPLERETYRKKTSHFFIEDHERQFQRWNDHCVRLLKHEFVRFKNAV 61
GVDE ++I +L K + +R+ + Q LK V
Sbjct: 58 GVDEATIIDILTKRNNAQRQQIKAA-----------YLQETGKPLDETLKKALTGHLEEV 106
Query: 62 VLWSMH-PWERDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEED 120
VL + P + DA + A+K LIEI +R+++E+ + Y + +D
Sbjct: 107 VLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKD 166
Query: 121 VASHIHGNDRKLLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRI 180
+ S G+ R L++L R E V +D A S+A+ L A + + + + I
Sbjct: 167 ITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDV---NVFNTI 223
Query: 181 LATRSKLXLQAVYTAL*R-------DFWEES*RGIINK*TLFKETVQCLCTPQVYFSKVL 233
L TRS L+ V+ + + +G I K V+C + +F++ L
Sbjct: 224 LTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEK--CLTAIVKCATSKPAFFAEKL 281
Query: 234 DAALKNDVNKNIKKSLTRVIVTRADIDMKEIKAEYNNLYGVSLPQKIEETAKGNYKDFLL 293
A+K ++ K+L R++V+R++IDM +IKA Y +YG+SL Q I + KG+Y+ L+
Sbjct: 282 HQAMKGVGTRH--KALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILV 339
Query: 294 TL 295
L
Sbjct: 340 AL 341
>ANX1_MOUSE (P10107) Annexin A1 (Annexin I) (Lipocortin I)
(Calpactin II) (Chromobindin 9) (P35) (Phospholipase A2
inhibitory protein)
Length = 345
Score = 88.6 bits (218), Expect = 2e-17
Identities = 79/302 (26%), Positives = 139/302 (45%), Gaps = 26/302 (8%)
Query: 2 GVDEKSLIAVLGKWDPLERETYRKKTSHFFIEDHERQFQRWNDHCVRLLKHEFVRFKNAV 61
GVDE ++I +L K +R+ + +++++ + +L+ V
Sbjct: 58 GVDEATIIDILTKRTNAQRQQIKAA----YLQENGKPLDE-------VLRKALTGHLEEV 106
Query: 62 VLWSMH-PWERDARLAKEALKKGSISYGVLIEIACTRSSEELLGARKAYHSLFDHSIEED 120
VL + P + DA + A+K LIEI TRS+E++ + Y + +D
Sbjct: 107 VLAMLKTPAQFDADELRGAMKGLGTDEDTLIEILTTRSNEQIREINRVYREELKRDLAKD 166
Query: 121 VASHIHGNDRKLLVALVSAYRYEGTKVKDDTAKSEAKTLSNAIKNAQNKPIVEDDEVIRI 180
+ S G+ RK L+AL R + V D A ++A+ L A + + + + I
Sbjct: 167 ITSDTSGDFRKALLALAKGDRCQDLSVNQDLADTDARALYEAGERRKGTDV---NVFTTI 223
Query: 181 LATRSKLXLQAVYTAL*RDFWEE-------S*RGIINK*TLFKETVQCLCTPQVYFSKVL 233
L +RS L+ V+ + + +G I K V+C + +F++ L
Sbjct: 224 LTSRSFPHLRRVFQNYGKYSQHDMNKALDLELKGDIEK--CLTTIVKCATSTPAFFAEKL 281
Query: 234 DAALKNDVNKNIKKSLTRVIVTRADIDMKEIKAEYNNLYGVSLPQKIEETAKGNYKDFLL 293
A+K ++ K+L R++V+R++IDM EIK Y YG+SL Q I + KG+Y+ L+
Sbjct: 282 YEAMKGAGTRH--KALIRIMVSRSEIDMNEIKVFYQKKYGISLCQAILDETKGDYEKILV 339
Query: 294 TL 295
L
Sbjct: 340 AL 341
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.324 0.138 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,865,646
Number of Sequences: 164201
Number of extensions: 1208378
Number of successful extensions: 4371
Number of sequences better than 10.0: 73
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 4070
Number of HSP's gapped (non-prelim): 165
length of query: 299
length of database: 59,974,054
effective HSP length: 110
effective length of query: 189
effective length of database: 41,911,944
effective search space: 7921357416
effective search space used: 7921357416
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Medicago: description of AC146590.14