BLAST2 result
BLASTP 2.2.2 [Dec-14-2001]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= AC146585.12 + phase: 0 /pseudo
(942 letters)
Database: sprot
164,201 sequences; 59,974,054 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AKH_DAUCA (P37142) Bifunctional aspartokinase/homoserine dehydro... 1301 0.0
AKH1_MAIZE (P49079) Bifunctional aspartokinase/homoserine dehydr... 1243 0.0
AKH2_MAIZE (P49080) Bifunctional aspartokinase/homoserine dehydr... 1201 0.0
AK1H_SERMA (P27725) Bifunctional aspartokinase/homoserine dehydr... 507 e-143
AK1H_ECOLI (P00561) Bifunctional aspartokinase/homoserine dehydr... 502 e-141
AKH_HAEIN (P44505) Bifunctional aspartokinase/homoserine dehydro... 489 e-137
AKH_BUCAI (P57290) Bifunctional aspartokinase/homoserine dehydro... 466 e-130
AKH_BUCAP (Q8K9U9) Bifunctional aspartokinase/homoserine dehydro... 462 e-129
AKH_BUCBP (Q89AR4) Bifunctional aspartokinase/homoserine dehydro... 407 e-113
DHOM_SCHPO (O94671) Probable homoserine dehydrogenase (EC 1.1.1.... 281 6e-75
AK_METJA (Q57991) Probable aspartokinase (EC 2.7.2.4) (Aspartate... 269 3e-71
DHOM_YEAST (P31116) Homoserine dehydrogenase (EC 1.1.1.3) (HDH) 252 4e-66
AK2H_ECOLI (P00562) Bifunctional aspartokinase/homoserine dehydr... 216 2e-55
AK_SCHPO (O60163) Probable aspartokinase (EC 2.7.2.4) (Aspartate... 176 3e-43
AK3_ECOLI (P08660) Lysine-sensitive aspartokinase III (EC 2.7.2.... 174 1e-42
AK_YEAST (P10869) Aspartokinase (EC 2.7.2.4) (Aspartate kinase) 169 2e-41
AK_THETH (P61489) Aspartokinase (EC 2.7.2.4) (Aspartate kinase) ... 142 4e-33
AK_THET2 (P61488) Aspartokinase (EC 2.7.2.4) (Aspartate kinase) ... 142 4e-33
AK2_BACSU (P08495) Aspartokinase 2 (EC 2.7.2.4) (Aspartokinase I... 141 7e-33
AK3_BACSU (P94417) Probable aspartokinase (EC 2.7.2.4) (Aspartat... 141 9e-33
>AKH_DAUCA (P37142) Bifunctional aspartokinase/homoserine
dehydrogenase, chloroplast precursor (AK-HD) (AK-HSDH)
[Includes: Aspartokinase (EC 2.7.2.4); Homoserine
dehydrogenase (EC 1.1.1.3)] (Fragment)
Length = 921
Score = 1301 bits (3367), Expect = 0.0
Identities = 677/947 (71%), Positives = 783/947 (82%), Gaps = 35/947 (3%)
Query: 4 SLSSSLSHFSRISVT---SLQHDYNNKIPADSQCRHFLLSRRFHSLRK-GITLPRRRESP 59
SLSS++S S ++ S + NK + L + SL K GI L R R+
Sbjct: 1 SLSSAISPSSYAAIAAAYSARTPIFNKKKTAAVLSPLSLFHQSPSLSKTGIFLHRGRKES 60
Query: 60 SSG--ICASLTDV--SVNVAVEEKELSKGDSWSVHKFGGTCMGSSQRIKNVGDIVLNDDS 115
SS I AS+T S++ +VE+ L +G WS+HKFGGTC+GSS+RI+NV +IV+ DDS
Sbjct: 61 SSKFYIAASVTTAVPSLDDSVEKVHLPRGAMWSIHKFGGTCVGSSERIRNVAEIVVEDDS 120
Query: 116 ERKLVVVSAMSKVTDMMYDLINKAQSRDESYISSLDAVLEKHSATAHDILDGETLAIFLS 175
ERKLVVVSAMSKVTDMMYDLI KAQSRD+SY S+LDAV+EKH TA D+LD + LA FL+
Sbjct: 121 ERKLVVVSAMSKVTDMMYDLIYKAQSRDDSYESALDAVMEKHKLTAFDLLDEDDLARFLT 180
Query: 176 KLHEDISNLKAMLRAIYIAGHVTESFTDFVVGHGELWSAQMLSLVIRKNGIDCKWMDTRE 235
+L D+ LKAMLRAIYIAGH TESF+DFVVGHGELWSAQ+LS VIRKNG DC WMDTR+
Sbjct: 181 RLQHDVITLKAMLRAIYIAGHATESFSDFVVGHGELWSAQLLSFVIRKNGGDCNWMDTRD 240
Query: 236 VLIVNPTSSNQVDPDYLESERRLEKWYSLNPCKVIIATGFIASTPENIPTTLKRDGSDFS 295
VL+VNP SNQVDPDYLESE+RLEKW+S N C+ I+ATGFIASTP+NIPTTLKRDGSDFS
Sbjct: 241 VLVVNPAGSNQVDPDYLESEKRLEKWFSSNQCQTIVATGFIASTPQNIPTTLKRDGSDFS 300
Query: 296 AAIMGSLFRARQVTIWTDVDGVYSADPRKVSEAVILKTLSYQEAWEMSYFGANVLHPRTI 355
AAIMG+L RA QVTIWTDV+GVYSADPRKVSEAV+LKTLSYQEAWEMSYFGANVLHPRTI
Sbjct: 301 AAIMGALLRAGQVTIWTDVNGVYSADPRKVSEAVVLKTLSYQEAWEMSYFGANVLHPRTI 360
Query: 356 IPVMRYGIPILIRNIFNLSAPGTKICHPVVSDYEDKSNLQNYVKGFATIDNLALVNVEGT 415
PVMRY IPI+IRNIFNLSAPGT IC V + ED L+++VKGFATIDNLAL+NVEGT
Sbjct: 361 NPVMRYDIPIVIRNIFNLSAPGTMICRESVGETEDGLKLESHVKGFATIDNLALINVEGT 420
Query: 416 GMAGVPGTASAIFAAVKDVGANVIMISQASSEHSVCFAVPEKEVKAVAEALQSRFRQALD 475
GMAGVPGTA+AIF AVKDVGANVIMISQASSEHS+CFAVPE EVKAVA+AL++RFRQALD
Sbjct: 421 GMAGVPGTATAIFGAVKDVGANVIMISQASSEHSICFAVPESEVKAVAKALEARFRQALD 480
Query: 476 NGRLSQVAVIPNCSILAAVGQKMASTPGVSATLFNALAKANINVRAIAQGCSEYNITVVI 535
GRLSQVA PNCSILA VGQKMASTPGVSATLFNALAKANINVRAIAQGC+EYNITVV+
Sbjct: 481 AGRLSQVANNPNCSILATVGQKMASTPGVSATLFNALAKANINVRAIAQGCTEYNITVVL 540
Query: 536 KREDSIKALRAVHSRFYLSRTTIAMGIIGPGLIGSTLLDQLRDQAKHSHLYISYLLHTRR 595
RED ++AL+AVHSRFYLSRTTIA+GI+GPGLIG+TLLDQLRDQA
Sbjct: 541 SREDCVRALKAVHSRFYLSRTTIAVGIVGPGLIGATLLDQLRDQA--------------A 586
Query: 596 LLEICGKLMQQFIQCRLQF*KKNLTLICV*WA*LAQSQCFSVMSKWKELREERGEVANLE 655
+L+ K I R+ + T++ S+ +S+W+E+++E+G+ A LE
Sbjct: 587 ILKENSK-----IDLRVMGITGSRTMLL--------SETGIDLSRWREVQKEKGQTAGLE 633
Query: 656 KFAQHVHGNNFIPNTALVDCTADSIIAGHYYEWLCKGIHVITPNKKANSGPLEQYLRLRA 715
KF QHV GN+FIP+T +VDCTADS +A HY++WLC+GIHVITPNKKANSGPL+QYL+LRA
Sbjct: 634 KFVQHVRGNHFIPSTVIVDCTADSEVASHYHDWLCRGIHVITPNKKANSGPLDQYLKLRA 693
Query: 716 LQRQSYTHYFYEATVGAGLPIVSTLRGLLETGDKILQIEGIFSGTLSYIFNNFKDGRAFS 775
LQR+SYTHYFYEATV AGLPI++TL+GLLETGDKIL+IEGIFSGTLSYIFNNFK FS
Sbjct: 694 LQRRSYTHYFYEATVVAGLPIITTLQGLLETGDKILRIEGIFSGTLSYIFNNFKSTTPFS 753
Query: 776 EVVGEAKEAGYTEPDPRDDLSGTDVARKVIILARESGLKLELSNIPIESLVPEPLRACAS 835
EVV EAK AGYTEPDPRDDL+GTDVARKVIILAR SGLKLELS+IP++SLVPEPLR AS
Sbjct: 754 EVVSEAKAAGYTEPDPRDDLAGTDVARKVIILARGSGLKLELSDIPVQSLVPEPLRGIAS 813
Query: 836 AQEFMQQLPKFDQEFAKKQEDADNAGEVLRYVGVVDVTNKKGVVELRKYKKDHPFAQLSG 895
A+EF+ QLP+FD + +K+EDA+NAGEVLRYVGVVD N+KGVVEL++YKK+HPFAQLSG
Sbjct: 814 AEEFLLQLPQFDSDMTRKREDAENAGEVLRYVGVVDAVNQKGVVELKRYKKEHPFAQLSG 873
Query: 896 SDNIIAFTTRRYKNQPLIVRGPGAGAQVTAGGIFSDILRLASYLGAP 942
SDNI AFTT RY QP I+RGPGAGA+VTAGG+FSDILRLASYLGAP
Sbjct: 874 SDNINAFTTERYNKQPPIIRGPGAGAEVTAGGVFSDILRLASYLGAP 920
>AKH1_MAIZE (P49079) Bifunctional aspartokinase/homoserine
dehydrogenase 1, chloroplast precursor (AK-HD 1)
(AK-HSDH 1) [Includes: Aspartokinase (EC 2.7.2.4);
Homoserine dehydrogenase (EC 1.1.1.3)]
Length = 920
Score = 1243 bits (3215), Expect = 0.0
Identities = 638/873 (73%), Positives = 727/873 (83%), Gaps = 30/873 (3%)
Query: 70 VSVNVAVEEKELSKGDSWSVHKFGGTCMGSSQRIKNVGDIVLNDDSERKLVVVSAMSKVT 129
VSV A +L KGD WSVHKFGGTCMG+S+RI NV DIVL D SERKLVVVSAMSKVT
Sbjct: 77 VSVEQAEAIADLPKGDMWSVHKFGGTCMGTSERIHNVADIVLRDPSERKLVVVSAMSKVT 136
Query: 130 DMMYDLINKAQSRDESYISSLDAVLEKHSATAHDILDGETLAIFLSKLHEDISNLKAMLR 189
DMMY+L+NKAQSRD+SYI+ LD V +KH TA D+L GE LA FLS+LH DISNLKAMLR
Sbjct: 137 DMMYNLVNKAQSRDDSYIAVLDEVFDKHMTTAKDLLAGEDLARFLSQLHADISNLKAMLR 196
Query: 190 AIYIAGHVTESFTDFVVGHGELWSAQMLSLVIRKNGIDCKWMDTREVLIVNPTSSNQVDP 249
AIYIAGH TESF+DFVVGHGELWSAQMLS I+K+G C WMDTREVL+VNP+ +NQVDP
Sbjct: 197 AIYIAGHATESFSDFVVGHGELWSAQMLSYAIQKSGTPCSWMDTREVLVVNPSGANQVDP 256
Query: 250 DYLESERRLEKWYSLNPCKVIIATGFIASTPENIPTTLKRDGSDFSAAIMGSLFRARQVT 309
DYLESE+RLEKW+S P + IIATGFIASTPENIPTTLKRDGSDFSAAI+GSL +ARQVT
Sbjct: 257 DYLESEKRLEKWFSRCPAETIIATGFIASTPENIPTTLKRDGSDFSAAIIGSLVKARQVT 316
Query: 310 IWTDVDGVYSADPRKVSEAVILKTLSYQEAWEMSYFGANVLHPRTIIPVMRYGIPILIRN 369
IWTDVDGV+SADPRKVSEAVIL TLSYQEAWEMSYFGANVLHPRTIIPVM+Y IPI+IRN
Sbjct: 317 IWTDVDGVFSADPRKVSEAVILSTLSYQEAWEMSYFGANVLHPRTIIPVMKYNIPIVIRN 376
Query: 370 IFNLSAPGTKICHPVVSDYEDKSNLQNYVKGFATIDNLALVNVEGTGMAGVPGTASAIFA 429
IFN SAPGT IC ++ D L+ VK FATID LALVNVEGTGMAGVPGTA+AIF
Sbjct: 377 IFNTSAPGTMICQQPANENGD---LEACVKAFATIDKLALVNVEGTGMAGVPGTANAIFG 433
Query: 430 AVKDVGANVIMISQASSEHSVCFAVPEKEVKAVAEALQSRFRQALDNGRLSQVAVIPNCS 489
AVKDVGANVIMISQASSEHSVCFAVPEKEV V+ AL +RFR+AL GRLS+V VI NCS
Sbjct: 434 AVKDVGANVIMISQASSEHSVCFAVPEKEVALVSAALHARFREALAAGRLSKVEVIHNCS 493
Query: 490 ILAAVGQKMASTPGVSATLFNALAKANINVRAIAQGCSEYNITVVIKREDSIKALRAVHS 549
ILA VG +MASTPGVSATLF+ALAKANINVRAIAQGCSEYNIT+V+K+ED ++ALRA HS
Sbjct: 494 ILATVGLRMASTPGVSATLFDALAKANINVRAIAQGCSEYNITIVLKQEDCVRALRAAHS 553
Query: 550 RFYLSRTTIAMGIIGPGLIGSTLLDQLRDQAKHSHLYISYLLHTRRLLEICGKLMQQFIQ 609
RF+LS+TT+A+GIIGPGLIG TLL+QL+DQA ++ L R++ I G
Sbjct: 554 RFFLSKTTLAVGIIGPGLIGRTLLNQLKDQAAVLKENMNIDL---RVMGIAGSRT----- 605
Query: 610 CRLQF*KKNLTLICV*WA*LAQSQCFSVMSKWKELREERGEVANLEKFAQHVHGNNFIPN 669
+ S +++WKE + E ANL+KF H+ N+F PN
Sbjct: 606 -------------------MLLSDIGVDLTQWKEKLQTEAEPANLDKFVHHLSENHFFPN 646
Query: 670 TALVDCTADSIIAGHYYEWLCKGIHVITPNKKANSGPLEQYLRLRALQRQSYTHYFYEAT 729
LVDCTAD+ +A HYY+WL KGIHVITPNKKANSGPL++YL+LR LQR SYTHYFYEAT
Sbjct: 647 RVLVDCTADTSVASHYYDWLKKGIHVITPNKKANSGPLDRYLKLRTLQRASYTHYFYEAT 706
Query: 730 VGAGLPIVSTLRGLLETGDKILQIEGIFSGTLSYIFNNFKDGRAFSEVVGEAKEAGYTEP 789
VGAGLPI+STLRGLLETGDKIL+IEGIFSGTLSYIFNNF+ R FS+VV EAK+AGYTEP
Sbjct: 707 VGAGLPIISTLRGLLETGDKILRIEGIFSGTLSYIFNNFEGARTFSDVVAEAKKAGYTEP 766
Query: 790 DPRDDLSGTDVARKVIILARESGLKLELSNIPIESLVPEPLRACASAQEFMQQLPKFDQE 849
DPRDDLSGTDVARKVIILARESGL LELS+IP+ SLVPE L++C SA E+MQ+LP FD++
Sbjct: 767 DPRDDLSGTDVARKVIILARESGLGLELSDIPVRSLVPEALKSCTSADEYMQKLPSFDED 826
Query: 850 FAKKQEDADNAGEVLRYVGVVDVTNKKGVVELRKYKKDHPFAQLSGSDNIIAFTTRRYKN 909
+A+++++A+ AGEVLRYVGVVDV +KKG VELR YK+DHPFAQLSGSDNIIAFTT RYK+
Sbjct: 827 WARERKNAEAAGEVLRYVGVVDVVSKKGQVELRAYKRDHPFAQLSGSDNIIAFTTSRYKD 886
Query: 910 QPLIVRGPGAGAQVTAGGIFSDILRLASYLGAP 942
QPLIVRGPGAGA+VTAGG+F DILRL+SYLGAP
Sbjct: 887 QPLIVRGPGAGAEVTAGGVFCDILRLSSYLGAP 919
>AKH2_MAIZE (P49080) Bifunctional aspartokinase/homoserine
dehydrogenase 2, chloroplast precursor (AK-HD 2)
(AK-HSDH 2) [Includes: Aspartokinase (EC 2.7.2.4);
Homoserine dehydrogenase (EC 1.1.1.3)]
Length = 917
Score = 1201 bits (3108), Expect = 0.0
Identities = 611/880 (69%), Positives = 715/880 (80%), Gaps = 34/880 (3%)
Query: 67 LTDVSVNVAVEEKE----LSKGDSWSVHKFGGTCMGSSQRIKNVGDIVLNDDSERKLVVV 122
L + ++VE+ E L KGD WSVHKFGGTCMG+ +RI+ V +IVL D SERKL++V
Sbjct: 67 LRPAAAAISVEQDEVNTYLPKGDMWSVHKFGGTCMGTPKRIQCVANIVLGDSSERKLIIV 126
Query: 123 SAMSKVTDMMYDLINKAQSRDESYISSLDAVLEKHSATAHDILDGETLAIFLSKLHEDIS 182
SAMSKVTDMMY+L+ KAQSRD+SY +L V EKH A D+LDGE LA FLS+LH D+S
Sbjct: 127 SAMSKVTDMMYNLVQKAQSRDDSYAIALAEVFEKHMTAAKDLLDGEDLARFLSQLHSDVS 186
Query: 183 NLKAMLRAIYIAGHVTESFTDFVVGHGELWSAQMLSLVIRKNGIDCKWMDTREVLIVNPT 242
NL+AMLRAIYIAGH TESF+DFVVGHGELWSAQMLS I+K+G C WMDTREVL+V P+
Sbjct: 187 NLRAMLRAIYIAGHATESFSDFVVGHGELWSAQMLSYAIKKSGAPCSWMDTREVLVVTPS 246
Query: 243 SSNQVDPDYLESERRLEKWYSLNPCKVIIATGFIASTPENIPTTLKRDGSDFSAAIMGSL 302
NQVDPDYLE E+RL+KW+S P ++I+ATGFIAST NIPTTLKRDGSDFSAAI+GSL
Sbjct: 247 GCNQVDPDYLECEKRLQKWFSRQPAEIIVATGFIASTAGNIPTTLKRDGSDFSAAIVGSL 306
Query: 303 FRARQVTIWTDVDGVYSADPRKVSEAVILKTLSYQEAWEMSYFGANVLHPRTIIPVMRYG 362
RARQVTIWTDVDGV+SADPRKVSEAVIL TLSYQEAWEMSYFGANVLHPRTIIPVM+
Sbjct: 307 VRARQVTIWTDVDGVFSADPRKVSEAVILSTLSYQEAWEMSYFGANVLHPRTIIPVMKDN 366
Query: 363 IPILIRNIFNLSAPGTKICHPVVSDYEDKSNLQNYVKGFATIDNLALVNVEGTGMAGVPG 422
IPI+IRN+FNLSAPGT IC ++ D L VK FAT+DNLALVNVEGTGMAGVPG
Sbjct: 367 IPIVIRNMFNLSAPGTMICKQPANENGD---LDACVKSFATVDNLALVNVEGTGMAGVPG 423
Query: 423 TASAIFAAVKDVGANVIMISQASSEHSVCFAVPEKEVKAVAEALQSRFRQALDNGRLSQV 482
TASAIF+AVKDVGANVIMISQASSEHSVCFAVPEKEV V+ L RFR+AL GRLS+V
Sbjct: 424 TASAIFSAVKDVGANVIMISQASSEHSVCFAVPEKEVAVVSAELHDRFREALAAGRLSKV 483
Query: 483 AVIPNCSILAAVGQKMASTPGVSATLFNALAKANINVRAIAQGCSEYNITVVIKREDSIK 542
VI CSILAAVG +MASTPGVSA LF+ALAKANINVRAIAQGCSEYNITVV+K++D ++
Sbjct: 484 EVINGCSILAAVGLRMASTPGVSAILFDALAKANINVRAIAQGCSEYNITVVLKQQDCVR 543
Query: 543 ALRAVHSRFYLSRTTIAMGIIGPGLIGSTLLDQLRDQAKHSHLYISYLLHTRRLLEICGK 602
ALRA HSRF+LS+TT+A+GIIGPGLIG LL+QL++Q ++ L R++ I G
Sbjct: 544 ALRAAHSRFFLSKTTLAVGIIGPGLIGGALLNQLKNQTAVLKENMNIDL---RVIGITGS 600
Query: 603 LMQQFIQCRLQF*KKNLTLICV*WA*LAQSQCFSVMSKWKELREERGEVANLEKFAQHVH 662
+ +++WK+L ++ E A++ F H+
Sbjct: 601 STMLLSDTGID------------------------LTQWKQLLQKEAEPADIGSFVHHLS 636
Query: 663 GNNFIPNTALVDCTADSIIAGHYYEWLCKGIHVITPNKKANSGPLEQYLRLRALQRQSYT 722
N+ PN LVDCTAD+ +A HYY+WL KGIHVITPNKKANSGPL+QYL+LR +QR SYT
Sbjct: 637 DNHVFPNKVLVDCTADTSVASHYYDWLKKGIHVITPNKKANSGPLDQYLKLRTMQRASYT 696
Query: 723 HYFYEATVGAGLPIVSTLRGLLETGDKILQIEGIFSGTLSYIFNNFKDGRAFSEVVGEAK 782
HYFYEATVGAGLPI+STLRGLLETGDKIL+IEGIFSGTLSYIFNNF+ RAFS+VV EA+
Sbjct: 697 HYFYEATVGAGLPIISTLRGLLETGDKILRIEGIFSGTLSYIFNNFEGTRAFSDVVAEAR 756
Query: 783 EAGYTEPDPRDDLSGTDVARKVIILARESGLKLELSNIPIESLVPEPLRACASAQEFMQQ 842
EAGYTEPDPRDDLSGTDVARKV++LARESGL+LELS+IP++SLVPE L +C+SA EFMQ+
Sbjct: 757 EAGYTEPDPRDDLSGTDVARKVVVLARESGLRLELSDIPVKSLVPETLASCSSADEFMQK 816
Query: 843 LPKFDQEFAKKQEDADNAGEVLRYVGVVDVTNKKGVVELRKYKKDHPFAQLSGSDNIIAF 902
LP FD+++A+++ DA+ AGEVLRYVG +D N+ G VELR+Y++DHPFAQLSGSDNIIAF
Sbjct: 817 LPSFDEDWARQRSDAEAAGEVLRYVGALDAVNRSGQVELRRYRRDHPFAQLSGSDNIIAF 876
Query: 903 TTRRYKNQPLIVRGPGAGAQVTAGGIFSDILRLASYLGAP 942
TT RYK QPLIVRGPGAGA+VTAGG+F DILRLASYLGAP
Sbjct: 877 TTSRYKEQPLIVRGPGAGAEVTAGGVFCDILRLASYLGAP 916
>AK1H_SERMA (P27725) Bifunctional aspartokinase/homoserine
dehydrogenase I (AKI-HDI) [Includes: Aspartokinase I (EC
2.7.2.4); Homoserine dehydrogenase I (EC 1.1.1.3)]
Length = 819
Score = 507 bits (1305), Expect = e-143
Identities = 303/864 (35%), Positives = 475/864 (54%), Gaps = 65/864 (7%)
Query: 89 VHKFGGTCMGSSQRIKNVGDIVLNDDSERKLV-VVSAMSKVTDMMYDLINKAQSRDESYI 147
V KFGGT + +++R V DI+ ++ + ++ V+SA +K+T+ + +I+K + +
Sbjct: 3 VLKFGGTSVANAERFLRVADIMESNARQGQVATVLSAPAKITNHLVAMIDKTVAGQDILP 62
Query: 148 SSLDAVLEKHSATAHDILDGETLAI-------FLSKLHEDISNLKAMLRAIYIAGHVTES 200
+ DA E+ A D+L G A+ + ++ + LK +L + + G +S
Sbjct: 63 NMSDA--ERIFA---DLLSGLAQALPGFEYDRLKGVVDQEFAQLKQVLHGVSLLGQCPDS 117
Query: 201 FTDFVVGHGELWSAQMLSLVIRKNGIDCKWMDTREVLIVNPTSSNQVDPDYLES-----E 255
++ GE S ++ V R G V ++NP YLES E
Sbjct: 118 VNAAIICRGEKLSIAIMEGVFRAKGYP--------VTVINPVEKLLAQGHYLESTVDIAE 169
Query: 256 RRLEKWYSLNPCK-VIIATGFIASTPENIPTTLKRDGSDFSAAIMGSLFRARQVTIWTDV 314
L + P +++ GF A + L R+GSD+SAA++ + RA IWTDV
Sbjct: 170 STLRIAAAAIPADHIVLMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDV 229
Query: 315 DGVYSADPRKVSEAVILKTLSYQEAWEMSYFGANVLHPRTIIPVMRYGIPILIRNIFNLS 374
DGVY+ DPR V +A +LK++SYQEA E+SYFGA VLHPRTI P+ ++ IP LI+N N
Sbjct: 230 DGVYTCDPRTVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTSNPQ 289
Query: 375 APGTKICHPVVSDYEDKSNLQNYVKGFATIDNLALVNVEGTGMAGVPGTASAIFAAVKDV 434
APGT I +D ++ VKG ++N+A++NV G GM G+ G A+ +FA +
Sbjct: 290 APGTLIG-------KDSTDADMPVKGITNLNNMAMINVSGPGMKGMVGMAARVFAVMSRA 342
Query: 435 GANVIMISQASSEHSVCFAVPEKEVKAVAEALQSRFRQALDNGRLSQVAVIPNCSILAAV 494
G +V++I+Q+SSE+S+ F VP+ E++ AL+ F L +G L + V+ +I++ V
Sbjct: 343 GISVVLITQSSSEYSISFCVPQGELQRARRALEEEFYLELKDGVLDPLDVMERLAIISVV 402
Query: 495 GQKMASTPGVSATLFNALAKANINVRAIAQGCSEYNITVVIKREDSIKALRAVHSRFYLS 554
G M + G+SA F+ALA+ANIN+ AIAQG SE +I+VV+ + + +R H + +
Sbjct: 403 GDGMRTLRGISARFFSALARANINIVAIAQGSSERSISVVVSNDSATTGVRVSHQMLFNT 462
Query: 555 RTTIAMGIIGPGLIGSTLLDQLRDQAKHSHLYISYLLHTRRLLEICGKLMQQFIQCRLQF 614
I + +IG G +G L++Q+ Q +L L +CG + + +
Sbjct: 463 DQVIEVFVIGVGGVGGALIEQIYRQQ-------PWLKQKHIDLRVCGIANSRVMLTNVH- 514
Query: 615 *KKNLTLICV*WA*LAQSQCFSVMSKWKELREERGEVANLEKFAQHVHGNNFIPNTALVD 674
+ W++ E NL + + V + + N +VD
Sbjct: 515 --------------------GIALDSWRDALAGAQEPFNLGRLIRLVKEYHLL-NPVIVD 553
Query: 675 CTADSIIAGHYYEWLCKGIHVITPNKKANSGPLEQYLRLRALQRQSYTHYFYEATVGAGL 734
CT+ +A Y ++L G HV+TPNKKAN+ + Y +LRA S+ + Y+ VGAGL
Sbjct: 554 CTSSQAVADQYVDFLADGFHVVTPNKKANTSSMNYYQQLRAAAAGSHRKFLYDTNVGAGL 613
Query: 735 PIVSTLRGLLETGDKILQIEGIFSGTLSYIFNNFKDGRAFSEVVGEAKEAGYTEPDPRDD 794
P++ L+ LL GD++++ GI SG+LS+IF +G + S +A+ GYTEPDPRDD
Sbjct: 614 PVIENLQNLLNAGDELVRFSGILSGSLSFIFGKLDEGLSLSAATLQARANGYTEPDPRDD 673
Query: 795 LSGTDVARKVIILARESGLKLELSNIPIESLVPEPLRACASAQEFMQQLPKFDQEFAKKQ 854
LSG DVARK++ILARE+G KLELS+I +E ++P A F+ +LP+ D+EFA+
Sbjct: 674 LSGMDVARKLLILAREAGYKLELSDIEVEPVLPPSFDASGDVDTFLARLPELDKEFARNV 733
Query: 855 EDADNAGEVLRYVGVVDVTNKKGVVELRKYKKDHPFAQLSGSDNIIAFTTRRYKNQPLIV 914
+A G+VLRYVG++D K V + + P ++ +N +AF +R Y+ PL++
Sbjct: 734 ANAAEQGKVLRYVGLIDEGRCK--VRIEAVDGNDPLYKVKNGENALAFYSRYYQPLPLVL 791
Query: 915 RGPGAGAQVTAGGIFSDILRLASY 938
RG GAG VTA G+F+D+LR S+
Sbjct: 792 RGYGAGNDVTAAGVFADLLRTLSW 815
>AK1H_ECOLI (P00561) Bifunctional aspartokinase/homoserine
dehydrogenase I (AKI-HDI) [Includes: Aspartokinase I (EC
2.7.2.4); Homoserine dehydrogenase I (EC 1.1.1.3)]
Length = 820
Score = 502 bits (1293), Expect = e-141
Identities = 309/857 (36%), Positives = 481/857 (56%), Gaps = 50/857 (5%)
Query: 89 VHKFGGTCMGSSQRIKNVGDIVLNDDSERKLV-VVSAMSKVTDMMYDLINKAQSRDESY- 146
V KFGGT + +++R V DI+ ++ + ++ V+SA +K+T+ + +I K S ++
Sbjct: 3 VLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTISGQDALP 62
Query: 147 -ISSLDAVLEKHSATAHDILDGETLAIFLSKLHEDISNLKAMLRAIYIAGHVTESFTDFV 205
IS + + + G LA + + ++ + +K +L I + G +S +
Sbjct: 63 NISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIKHVLHGISLLGQCPDSINAAL 122
Query: 206 VGHGELWSAQMLSLVIRKNGIDCKWMDTREVLI-VNPTSSNQVDPDYLESERRLEKWYSL 264
+ GE S +++ V+ G + +D E L+ V + VD ES RR+ S
Sbjct: 123 ICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHYLESTVD--IAESTRRIAA--SR 178
Query: 265 NPCK-VIIATGFIASTPENIPTTLKRDGSDFSAAIMGSLFRARQVTIWTDVDGVYSADPR 323
P +++ GF A + L R+GSD+SAA++ + RA IWTDVDGVY+ DPR
Sbjct: 179 IPADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPR 238
Query: 324 KVSEAVILKTLSYQEAWEMSYFGANVLHPRTIIPVMRYGIPILIRNIFNLSAPGTKICHP 383
+V +A +LK++SYQEA E+SYFGA VLHPRTI P+ ++ IP LI+N N APGT
Sbjct: 239 QVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTGNPQAPGT----- 293
Query: 384 VVSDYEDKSNLQNYVKGFATIDNLALVNVEGTGMAGVPGTASAIFAAVKDVGANVIMISQ 443
++ D+ L VKG + ++N+A+ +V G GM G+ G A+ +FAA+ +V++I+Q
Sbjct: 294 LIGASRDEDELP--VKGISNLNNMAMFSVSGPGMKGMVGMAARVFAAMSRARISVVLITQ 351
Query: 444 ASSEHSVCFAVPEKEVKAVAEALQSRFRQALDNGRLSQVAVIPNCSILAAVGQKMASTPG 503
+SSE+S+ F VP+ + A+Q F L G L +AV +I++ VG M + G
Sbjct: 352 SSSEYSISFCVPQSDCVRAERAMQEEFYLELKEGLLEPLAVTERLAIISVVGDGMRTLRG 411
Query: 504 VSATLFNALAKANINVRAIAQGCSEYNITVVIKREDSIKALRAVHSRFYLSRTTIAMGII 563
+SA F ALA+ANIN+ AIAQG SE +I+VV+ +D+ +R H + + I + +I
Sbjct: 412 ISAKFFAALARANINIVAIAQGSSERSISVVVNNDDATTGVRVTHQMLFNTDQVIEVFVI 471
Query: 564 GPGLIGSTLLDQLRDQAKHSHLYISYLLHTRRLLEICGKLMQQFIQCRLQF*KKNLTLIC 623
G G +G LL+QL+ Q S+L + L +CG + + + L L
Sbjct: 472 GVGGVGGALLEQLKRQQ-------SWLKNKHIDLRVCGVANSKALLTNVH----GLNL-- 518
Query: 624 V*WA*LAQSQCFSVMSKWKELREERGEVANLEKFAQHVHGNNFIPNTALVDCTADSIIAG 683
W+E + E NL + + V + + N +VDCT+ +A
Sbjct: 519 ---------------ENWQEELAQAKEPFNLGRLIRLVKEYHLL-NPVIVDCTSSQAVAD 562
Query: 684 HYYEWLCKGIHVITPNKKANSGPLEQYLRLRALQRQSYTHYFYEATVGAGLPIVSTLRGL 743
Y ++L +G HV+TPNKKAN+ ++ Y +LR +S + Y+ VGAGLP++ L+ L
Sbjct: 563 QYADFLREGFHVVTPNKKANTSSMDYYHQLRYAAEKSRRKFLYDTNVGAGLPVIENLQNL 622
Query: 744 LETGDKILQIEGIFSGTLSYIFNNFKDGRAFSEVVGEAKEAGYTEPDPRDDLSGTDVARK 803
L GD++++ GI SG+LSYIF +G +FSE A+E GYTEPDPRDDLSG DVARK
Sbjct: 623 LNAGDELMKFSGILSGSLSYIFGKLDEGMSFSEATTLAREMGYTEPDPRDDLSGMDVARK 682
Query: 804 VIILARESGLKLELSNIPIESLVPEPLRACASAQEFMQQLPKFDQEFAKKQEDADNAGEV 863
++ILARE+G +LEL++I IE ++P A FM L + D FA + A + G+V
Sbjct: 683 LLILARETGRELELADIEIEPVLPAEFNAEGDVAAFMANLSQLDDLFAARVAKARDEGKV 742
Query: 864 LRYVGVVDVTNKKGV--VELRKYKKDHPFAQLSGSDNIIAFTTRRYKNQPLIVRGPGAGA 921
LRYVG +D + GV V++ + + P ++ +N +AF + Y+ PL++RG GAG
Sbjct: 743 LRYVGNID---EDGVCRVKIAEVDGNDPLFKVKNGENALAFYSHYYQPLPLVLRGYGAGN 799
Query: 922 QVTAGGIFSDILRLASY 938
VTA G+F+D+LR S+
Sbjct: 800 DVTAAGVFADLLRTLSW 816
>AKH_HAEIN (P44505) Bifunctional aspartokinase/homoserine
dehydrogenase (AK-HD) [Includes: Aspartokinase (EC
2.7.2.4); Homoserine dehydrogenase (EC 1.1.1.3)]
Length = 815
Score = 489 bits (1259), Expect = e-137
Identities = 311/862 (36%), Positives = 467/862 (54%), Gaps = 69/862 (8%)
Query: 89 VHKFGGTCMGSSQRIKNVGDIVLNDDSERKLV-VVSAMSKVTDMMYDLINKA---QSRDE 144
V KFGGT + + +R ++ E + V+SA +K+T+ + L KA QS D
Sbjct: 3 VLKFGGTSLANPERFSQAAKLIEQAHLEEQAAGVLSAPAKITNHLVALSEKAALNQSTDT 62
Query: 145 SYISSLDAVLE----KHSATAHDILDGETLAIFLSKLHEDISNLKAMLRAIYIAGHVTES 200
+ +++ H+ L+G I + +K +L I AG V ++
Sbjct: 63 HFNEAIEIFYNIINGLHTENNQFDLNGTKALI-----DAEFVQIKGLLEEIRQAGKVEDA 117
Query: 201 FTDFVVGHGELWSAQMLSLVIRKNGIDCKWMDTR--EVLIVNPTSSNQVDPDYLESERRL 258
+ GE S M+ W + R V IV+P YLES +
Sbjct: 118 VKATIDCRGEKLSIAMMKA----------WFEARGYSVHIVDPVKQLLAKGGYLESSVEI 167
Query: 259 EKWY------SLNPCKVIIATGFIASTPENIPTTLKRDGSDFSAAIMGSLFRARQVTIWT 312
E+ ++ KV++ GF A + L R+GSD+SAA + + A IWT
Sbjct: 168 EESTKRVDAANIAKDKVVLMAGFTAGNEKGELVLLGRNGSDYSAACLAACLGASVCEIWT 227
Query: 313 DVDGVYSADPRKVSEAVILKTLSYQEAWEMSYFGANVLHPRTIIPVMRYGIPILIRNIFN 372
DVDGVY+ DPR V +A +L TLSY+EA E+SYFGA V+HPRTI P++ IP +I+N N
Sbjct: 228 DVDGVYTCDPRLVPDARLLPTLSYREAMELSYFGAKVIHPRTIGPLLPQNIPCVIKNTGN 287
Query: 373 LSAPGTKICHPVVSDYEDKSNLQNYVKGFATIDNLALVNVEGTGMAGVPGTASAIFAAVK 432
SAPG+ I V S+ +LQ VKG +DNLA+ NV G GM G+ G AS +F+A+
Sbjct: 288 PSAPGSIIDGNVKSE-----SLQ--VKGITNLDNLAMFNVSGPGMQGMVGMASRVFSAMS 340
Query: 433 DVGANVIMISQASSEHSVCFAVPEKEVKAVAEALQSRFRQALDNGRLSQVAVIPNCSILA 492
G +VI+I+Q+SSE+S+ F VP K + L++ F L+ +L + VI + SI++
Sbjct: 341 GAGISVILITQSSSEYSISFCVPVKSAEVAKTVLETEFANELNEHQLEPIEVIKDLSIIS 400
Query: 493 AVGQKMASTPGVSATLFNALAKANINVRAIAQGCSEYNITVVIKREDSIKALRAVHSRFY 552
VG M G++A F+ALA+ANI++ AIAQG SE +I+ V+ + +I+A++A H +
Sbjct: 401 VVGDGMKQAKGIAARFFSALAQANISIVAIAQGSSERSISAVVPQNKAIEAVKATHQALF 460
Query: 553 LSRTTIAMGIIGPGLIGSTLLDQLRDQAKHSHLYISYLLHTRRLLEICGKLMQQFIQCRL 612
++ + M ++G G +G L++Q++ Q + YL + +C R+
Sbjct: 461 NNKKVVDMFLVGVGGVGGELIEQVKRQKE-------YLAKKNVEIRVCAIANSN----RM 509
Query: 613 QF*KKNLTLICV*WA*LAQSQCFSVMSKWKELREERGEVANLEKFAQHVHGNNFIPNTAL 672
+ L L WK E + ++ + + ++ + N
Sbjct: 510 LLDENGLNL-----------------EDWKNDLENATQPSDFDVLLSFIKLHHVV-NPVF 551
Query: 673 VDCTADSIIAGHYYEWLCKGIHVITPNKKANSGPLEQYLRLRALQRQSYTHYFYEATVGA 732
VDCT+ +AG Y L +G HV+TPNKKAN+ L Y LR + S + YE VGA
Sbjct: 552 VDCTSAESVAGLYARALKEGFHVVTPNKKANTRELVYYNELRQNAQASQHKFLYETNVGA 611
Query: 733 GLPIVSTLRGLLETGDKILQIEGIFSGTLSYIFNNFKDGRAFSEVVGEAKEAGYTEPDPR 792
GLP++ L+ LL GD++ EGI SG+LS+IF ++G + SEV A+E G+TEPDPR
Sbjct: 612 GLPVIENLQNLLAAGDELEYFEGILSGSLSFIFGKLEEGLSLSEVTALAREKGFTEPDPR 671
Query: 793 DDLSGTDVARKVIILARESGLKLELSNIPIESLVPEPLRACASAQEFMQQLPKFDQEFAK 852
DDLSG DVARK++ILARE+G++LELS++ +E ++P+ SA EFM LP+ D+EF
Sbjct: 672 DDLSGQDVARKLLILAREAGIELELSDVEVEGVLPKGFSDGKSADEFMAMLPQLDEEFKT 731
Query: 853 KQEDADNAGEVLRYVGVVDVTNKKGVVELRKYKKDHPFAQLSGSDNIIAFTTRRYKNQPL 912
+ A G+VLRYVG ++ K V + ++P ++ +N +AF TR Y+ PL
Sbjct: 732 RVATAKAEGKVLRYVG--KISEGKCKVSIVAVDLNNPLYKVKDGENALAFYTRYYQPIPL 789
Query: 913 IVRGPGAGAQVTAGGIFSDILR 934
++RG GAG VTA GIF+DILR
Sbjct: 790 LLRGYGAGNAVTAAGIFADILR 811
>AKH_BUCAI (P57290) Bifunctional aspartokinase/homoserine
dehydrogenase (AK-HD) [Includes: Aspartokinase (EC
2.7.2.4); Homoserine dehydrogenase (EC 1.1.1.3)]
Length = 816
Score = 466 bits (1198), Expect = e-130
Identities = 281/873 (32%), Positives = 477/873 (54%), Gaps = 87/873 (9%)
Query: 91 KFGGTCMGSSQRIKNVGDIVL-NDDSERKLVVVSAMSKVTDMMYDLINKAQSRDES---- 145
KFGGT + ++++ +V I+ N +++ VV+SA +K+T+ + +I ++
Sbjct: 5 KFGGTSLANAEKFLSVSSIIEENTQTDQIAVVLSAPAKITNYLVKIIENTIKNNQILETV 64
Query: 146 ------YISSLDAVLEKHSATAHDILDGETLAIFLSKLHEDISNLKAMLRAIYIAGHVTE 199
++ ++ L S H ++ + ++ + LK +++ I + +
Sbjct: 65 HLAENIFMQLINNFLNIQSNFPHKEIE--------KIIKKEFNELKNIIQGILLLKQCPD 116
Query: 200 SFTDFVVGHGELWSAQMLSLVIRKNGIDCKWMDTREVLIVNPTSS------NQVDP--DY 251
+ ++ GE+ S ++ +++ + V I+NP + N +D D
Sbjct: 117 NIRAIIISRGEILSVFIMKSILQSKNYN--------VTIINPVKNLVAIGDNYLDSTVDI 168
Query: 252 LESERRLEKWYSLNPCKVIIATGFIASTPENIPTTLKRDGSDFSAAIMGSLFRARQVTIW 311
ES++ ++ ++N +I+ GFIA + L R+GSD+SAA++ + A IW
Sbjct: 169 SESKKNIQNM-NINQSNIILMAGFIAGNKDKKLVVLGRNGSDYSAAVLAACLDANCCEIW 227
Query: 312 TDVDGVYSADPRKVSEAVILKTLSYQEAWEMSYFGANVLHPRTIIPVMRYGIPILIRNIF 371
TDVDGV+++DPRKV A +LK++SYQEA E+SYFGA VLHPRTI P+ ++ IP LI+N
Sbjct: 228 TDVDGVFTSDPRKVPNARLLKSISYQEAMELSYFGAKVLHPRTIEPIAQFKIPCLIKNTN 287
Query: 372 NLSAPGTKICHPVVSDYEDKSNLQNYVKGFATIDNLALVNVEGTGMAGVPGTASAIFAAV 431
N+ + GT IC E + ++++KG +D +A+ N+ G + V S IF +
Sbjct: 288 NVKSIGTLIC-------EQNCSEKDFLKGVTHLDEIAMFNISGPHIKDVGSVISRIFTMM 340
Query: 432 KDVGANVIMISQASSEHSVCFAVPEKEVKAVAEALQSRFRQALDNGRLSQVAVIPNCSIL 491
+++I+Q+SSE+ + F V E ++ + F+ L +G L+ + N SIL
Sbjct: 341 SRGNIKILLITQSSSENKINFCVYEHDIYKILYLFNKEFQLELKDGLLNPFKIKKNLSIL 400
Query: 492 AAVGQKMASTPGVSATLFNALAKANINVRAIAQGCSEYNITVVIKREDSIKALRAVHSRF 551
+ VG + +++ +F+ L INV AI+QG S+++I++VIK+E+ +KA++ VH+
Sbjct: 401 SIVGSNIYKKHNIASKIFSVLGALKINVIAISQGSSKHSISLVIKKENILKAVQHVHNTL 460
Query: 552 YLSRTTIAMGIIGPGLIGSTLLDQLRDQAKHSHLYISYLLHTRRLLEICGKLMQQFIQCR 611
+ ++ TI M +IG G IGSTLL+Q+ Q +QF+
Sbjct: 461 FFNKKTIHMFLIGIGGIGSTLLNQILKQ-------------------------KQFLD-- 493
Query: 612 LQF*KKNLTL-ICV*WA*LAQSQCFSV------MSKWKELREERGEVANLEKFAQHVHGN 664
KKN+ + IC +A S+ + +S WK ++ + NLE + N
Sbjct: 494 ----KKNIEIKICA----IANSKKILLLDNTNDLSNWKNDFKKSTQKFNLELLNNLIKNN 545
Query: 665 NFIPNTALVDCTADSIIAGHYYEWLCKGIHVITPNKKANSGPLEQYLRLRALQRQSYTHY 724
+F N+ +VDCT+ +++ Y ++ HV+T NKKAN+ Y ++R Q+ +
Sbjct: 546 HF-SNSVIVDCTSSQLLSEQYVNFIDNNFHVVTSNKKANTSEWNYYKKIRKSVAQTGKKF 604
Query: 725 FYEATVGAGLPIVSTLRGLLETGDKILQIEGIFSGTLSYIFNNFKDGRAFSEVVGEAKEA 784
YE VGAGLP++ TL+ L ++GD ++ +GI SG+LS+IF ++G S+ EAKE
Sbjct: 605 LYETNVGAGLPVIETLQNLFKSGDNLICFKGILSGSLSFIFGRLEEGILLSQATREAKEL 664
Query: 785 GYTEPDPRDDLSGTDVARKVIILARESGLKLELSNIPIESLVPEPLRACASAQEFMQQLP 844
G+TEP+P DDLSG DVARK++ILARESG +EL +I IE L+P + +F+ +L
Sbjct: 665 GFTEPNPCDDLSGIDVARKLLILARESGYNIELKDIKIEPLLPNNFKIYEDTDKFLLKLK 724
Query: 845 KFDQEFAKKQEDADNAGEVLRYVGVVDVTNKKGVVELRKYKKDHPFAQLSGSDNIIAFTT 904
+ D F+ K + A N G VLR+V ++ ++ ++L + ++P ++ +N +AF T
Sbjct: 725 ELDVYFSNKIKQALNVGNVLRFVATIE-QKRQFFIKLEEVNINNPLYKVKNGENALAFYT 783
Query: 905 RRYKNQPLIVRGPGAGAQVTAGGIFSDILRLAS 937
Y+ PL++RG GAG VTA G+FSD+LR S
Sbjct: 784 NYYQPIPLVLRGYGAGNNVTASGVFSDLLRTLS 816
>AKH_BUCAP (Q8K9U9) Bifunctional aspartokinase/homoserine
dehydrogenase (AK-HD) [Includes: Aspartokinase (EC
2.7.2.4); Homoserine dehydrogenase (EC 1.1.1.3)]
Length = 814
Score = 462 bits (1190), Expect = e-129
Identities = 275/859 (32%), Positives = 472/859 (54%), Gaps = 65/859 (7%)
Query: 91 KFGGTCMGSSQRIKNVGDIVLNDDSERKL-VVVSAMSKVTDMMYDLINKAQSRDESYISS 149
KFGGT + ++++ V DI+ + + ++ VV+SA +K+T+ + +I D+ +
Sbjct: 5 KFGGTSLANAKKFLCVADIIEKKNKKEQIAVVLSAPAKITNYLATIIEN--KIDDEVLKK 62
Query: 150 LDAVLEKHSATAHDILDGETLAIF---LSKLHEDISNLKAMLRAIYIAGHVTESFTDFVV 206
++ DI + L + S + + + LK ++ I + E ++
Sbjct: 63 INLAKNIFIELIQDIKRIQPLFPYENTKSTIEIEFNKLKKIINGILLIKQCPEGIKPIII 122
Query: 207 GHGELWSAQMLSLVIRKNGIDCKWMDTREVLIVNPTSS-----NQVDP--DYLESERRLE 259
GE+ S ++ +++ EV I+NP ++ N +D D ES++R++
Sbjct: 123 SRGEILSVDIMKNILQSRN--------HEVTILNPVTNLLSIGNYLDSTIDIKESKKRIK 174
Query: 260 KWYSLNPCKVIIATGFIASTPENIPTTLKRDGSDFSAAIMGSLFRARQVTIWTDVDGVYS 319
K +++ +I+ GFIA E L R+GSD+SAAI+ S A+ IWTDVDGV +
Sbjct: 175 K-INIDQKNIILMAGFIAGNKEGELVVLGRNGSDYSAAILASCLNAKCCEIWTDVDGVLT 233
Query: 320 ADPRKVSEAVILKTLSYQEAWEMSYFGANVLHPRTIIPVMRYGIPILIRNIFNLSAPGTK 379
ADPR VS +L +SYQEA E+SYFGA VLHPRTI P+ ++ IP +I+N N + GT
Sbjct: 234 ADPRIVSNTYLLDYISYQEAMELSYFGAKVLHPRTIEPISQFQIPCVIKNTNNTESKGTW 293
Query: 380 ICHPVVSDYEDKSNLQNYVKGFATIDNLALVNVEGTGMAGVPGTASAIFAAVKDVGANVI 439
I ++ + N +KG +DN+ + N+ G+ + T + IF + +I
Sbjct: 294 I-------GKENNPSDNSLKGVTYLDNIIMFNISGSCLKDSGNTIARIFTILSRESMKII 346
Query: 440 MISQASSEHSVCFAVPEKEVKAVAEALQSRFRQALDNGRLSQVAVIPNCSILAAVGQKMA 499
+I Q+SSE+ + F EK++ + L+ F + G L+ ++ N +IL+ +G ++
Sbjct: 347 LIIQSSSENQINFCTFEKDIDYILLILKKEFTLEIKEGLLNDFNIVKNLTILSVIGSNIS 406
Query: 500 STPGVSATLFNALAKANINVRAIAQGCSEYNITVVIKREDSIKALRAVHSRFYLSRTTIA 559
+++ +F++L + INV AIA G S+++I++VIK+E+ ++ ++ +H+ + +T I
Sbjct: 407 EKNNIASKIFSSLGSSKINVLAIAHGSSKHSISIVIKKENLLQGIQNIHNTLFFKKTIIN 466
Query: 560 MGIIGPGLIGSTLLDQLRDQAK---HSHLYISYLLHTRRLLEICGKLMQQFIQCRLQF*K 616
+ +IG G +G LL Q+ Q K ++ I + R++ KL+ F K
Sbjct: 467 VFLIGIGGVGKALLKQILKQEKFLDQKNIKIQF-----RMIANSKKLL---------FLK 512
Query: 617 KNLTLICV*WA*LAQSQCFSVMSKWKELREERGEVANLEKFAQHVHGNNFIPNTALVDCT 676
++ L + W+E ++ E NL + N N+ ++DCT
Sbjct: 513 NSINL-----------------NNWEENFKKSKEKFNL-TILNELLKNTCDSNSVIIDCT 554
Query: 677 ADSIIAGHYYEWLCKGIHVITPNKKANSGPLEQYLRLRALQRQSYTHYFYEATVGAGLPI 736
+D I++ Y ++ KG H+IT NKKAN+ L+ Y +R + + YE VGAGLP+
Sbjct: 555 SDYILSKQYISFIKKGFHIITSNKKANTDSLKYYSEIRTTALKENKKFLYETNVGAGLPV 614
Query: 737 VSTLRGLLETGDKILQIEGIFSGTLSYIFNNFKDGRAFSEVVGEAKEAGYTEPDPRDDLS 796
++TL+ L TGD ++ +GI SG+LS+IF ++G SE EAK+ G+TEP+P DDLS
Sbjct: 615 INTLQSLFSTGDCLISFKGILSGSLSFIFGKLEEGVLLSEATKEAKKLGFTEPNPFDDLS 674
Query: 797 GTDVARKVIILARESGLKLELSNIPIESLVPEPLRACASAQEFMQQLPKFDQEFAKKQED 856
G DVARK+++LARE G +EL +I IE ++PE + +++EF+ +L + D F+++
Sbjct: 675 GIDVARKLLVLAREIGYSIELKDISIEPILPERFKKYQNSEEFLFKLKELDSFFSERVNK 734
Query: 857 ADNAGEVLRYVGVVDVTNKKGVVELRKYKKDHPFAQLSGSDNIIAFTTRRYKNQPLIVRG 916
A + G VLR++G ++ N K V++ + ++P ++ +N + F T Y+ PL++RG
Sbjct: 735 ARDIGNVLRFIGSIE-KNGKCSVKIEEINSNNPLYKVKNGENALTFYTNYYQPIPLVLRG 793
Query: 917 PGAGAQVTAGGIFSDILRL 935
GAG VTA G+FSD+LR+
Sbjct: 794 YGAGNDVTASGVFSDLLRI 812
>AKH_BUCBP (Q89AR4) Bifunctional aspartokinase/homoserine
dehydrogenase (AK-HD) [Includes: Aspartokinase (EC
2.7.2.4); Homoserine dehydrogenase (EC 1.1.1.3)]
Length = 816
Score = 407 bits (1046), Expect = e-113
Identities = 260/865 (30%), Positives = 450/865 (51%), Gaps = 75/865 (8%)
Query: 91 KFGGTCMGSSQRIKNVGDIVLND-DSERKLVVVSAMSKVTDMMYDLINKAQSRDESYISS 149
KFGGT + +S+ +V I+ N+ ++E+ +V+SA T+++ IN+ + +++ I
Sbjct: 5 KFGGTSLSNSELFFHVATIIENNLNNEQIAIVLSAPGNTTNLLEIAINQTIN-NKNIIPI 63
Query: 150 LDAVLEKHSATAHDILDGETLAIFLSKLHEDISN----LKAMLRAIYIAGHVTESFTDFV 205
+ + + +DI E ++ K+ +I N LK +L+ I + + +
Sbjct: 64 VQKIEKNFLKLINDIYQVEQKLLY-EKIKNNIENKLLELKNLLQGINLLRQCPDKIRAKI 122
Query: 206 VGHGELWSAQMLSLVIRKNGIDCKWMD------TREVLIVNPTSSNQVDPDYLESERRLE 259
+ GE S +++ ++ G + +D T+E +N T + ++ + S ++
Sbjct: 123 ISSGEYLSISIMNSILISRGYNTTIIDPVKKLLTKEDTYLNATVNIKISKFRILS-MKIP 181
Query: 260 KWYSLNPCKVIIATGFIASTPENIPTTLKRDGSDFSAAIMGSLFRARQVTIWTDVDGVYS 319
K + +I+ GF A + TL R+GSD+SA I+ + IWTDV+GVY+
Sbjct: 182 KHH------IILMPGFTAGNKQGELVTLGRNGSDYSATILSVCLNSTMCEIWTDVNGVYT 235
Query: 320 ADPRKVSEAVILKTLSYQEAWEMSYFGANVLHPRTIIPVMRYGIPILIRNIFNLSAPGTK 379
DP+ VS+A +L +LSY+EA E+SY GA +LHP TI P+ ++ IP I+N N S+ GTK
Sbjct: 236 CDPKLVSDAKLLTSLSYREAIELSYLGAKILHPNTIYPIQKFKIPCTIKNTHNPSSIGTK 295
Query: 380 I-CHPVVSDYEDKSNLQNYVKGFATIDNLALVNVEGTGMAGVPGTASAIFAAVKDVGANV 438
I C+ V + +N + G ++N+ + ++ + IF+ + +
Sbjct: 296 ISCNHVKN--------KNLITGVTYLENVHMFSISCLYSKNIETIIPKIFSCMSLSKIWI 347
Query: 439 IMISQASSEHSVCFAVPEKEVKAVAEALQSRFRQALDNGRLSQVAVIPNCSILAAVGQKM 498
I+ Q SS++++ F + + L L + L + V ++++ + +
Sbjct: 348 ILTIQTSSQNTISFCILKTMTNTALHVLHKALYLELKHKLLKPIKVEKKLTLISVISSDI 407
Query: 499 ASTPGVSATLFNALAKANINVRAIAQGCSEYNITVVIKREDSIKALRAVHSRFYLSRTTI 558
+ ++ +F+ L NIN AI++G S+ +I++V+K +D I +RA+H + T
Sbjct: 408 LNNTKITEKVFSILKHVNINTLAISKGASKNSISIVVKHDDGILGVRALHKGIFNKNCTA 467
Query: 559 AMGIIGPGLIGSTLLDQLRDQAKHSHLYISYLLHTRRLLEICGKLMQQFIQCRLQF*KKN 618
+ +IG G +G T L Q+ +Q ++L L+ICG
Sbjct: 468 EIFLIGIGRVGQTFLKQIIEQK-------NWLKSKNIDLKICG----------------- 503
Query: 619 LTLICV*WA*LAQSQCFSVM------SKWKELREERGEVANLEKFAQHVHGNNFIPNTAL 672
+A S+ F + WK + N + + N ++ N +
Sbjct: 504 ----------IANSKNFILNLDGINPKNWKRDLNLSKKSFNFKHLLNSIQ-NYYLINPII 552
Query: 673 VDCTADSIIAGHYYEWLCKGIHVITPNKKANSGPLEQYLRLRALQRQSYTHYFYEATVGA 732
VDCT+D IA Y ++ G H++TPNKKAN+ + Y +R ++ +FYE VGA
Sbjct: 553 VDCTSDKNIANQYISFINCGFHIVTPNKKANTTNWKYYEDIRLAAQKEKKKFFYETNVGA 612
Query: 733 GLPIVSTLRGLLETGDKILQIEGIFSGTLSYIFNNFKDGRAFSEVVGEAKEAGYTEPDPR 792
GLP++ L+ LL TGD ++ +GI SG+LS+IF +D + SE +A+ G+TEP+P+
Sbjct: 613 GLPVIENLKNLLRTGDTLIHFKGILSGSLSFIFGKLEDNISLSEATKQAQSLGFTEPNPK 672
Query: 793 DDLSGTDVARKVIILARESGLKLELSNIPIESLVPEPLRACASAQEFMQQLPKFDQEFAK 852
DDLSG DVARK++ILARE G KLEL +I IE L+P+ ++ +F+ +L + DQ F
Sbjct: 673 DDLSGIDVARKLLILAREVGYKLELKDIKIEPLLPKEFNNISNTTDFITKLKELDQIFCN 732
Query: 853 KQEDADNAGEVLRYVGVVDVTNKKGVVELRKYKKDH--PFAQLSGSDNIIAFTTRRYKNQ 910
+ + A G+ LR+VG++ N+KG +++ + DH P + +N +AF ++ Y+
Sbjct: 733 RVKKARKLGKRLRFVGII---NQKGNCQVKIDEVDHNDPLYNIKNGENALAFYSKYYQPI 789
Query: 911 PLIVRGPGAGAQVTAGGIFSDILRL 935
PL++RG GAG VTA GIFSD+LR+
Sbjct: 790 PLVLRGYGAGNNVTASGIFSDVLRI 814
>DHOM_SCHPO (O94671) Probable homoserine dehydrogenase (EC 1.1.1.3)
(HDH)
Length = 376
Score = 281 bits (719), Expect = 6e-75
Identities = 167/394 (42%), Positives = 240/394 (60%), Gaps = 33/394 (8%)
Query: 554 SRTTIAMGIIGPGLIGSTLLDQLRDQAKHSHLYISYLLHTRRLLEICGKLMQQFIQCRLQ 613
SRT + + I+G G IG LL+Q++ +++ + + + + G + + Q
Sbjct: 4 SRTNVNVAIVGTGNIGGELLNQIKGFNENASTNGTTSFNVVAISSMEGHYVSKDYQ---- 59
Query: 614 F*KKNLTLICV*WA*LAQSQCFSVMSKWKELREERGEVANLEKFAQHVHGNNFIPNTALV 673
NL S+WK L + +L+ + + +P LV
Sbjct: 60 --PINL-------------------SEWKNLTSQNQGAYSLDALVDFL-AKSPLP-AILV 96
Query: 674 DCTADSIIAGHYYEWLCKGIHVITPNKKANSGPLEQYLRLRALQRQSYTHYFYEATVGAG 733
D TA IA Y ++L K I++ TPNKKA S + Y + ++S +EA+VGAG
Sbjct: 97 DNTASEAIAQSYPKFLSKKINIATPNKKAFSASNDVYQNIIKASKESGALLMHEASVGAG 156
Query: 734 LPIVSTLRGLLETGDKILQIEGIFSGTLSYIFN----NFKDGRA-FSEVVGEAKEAGYTE 788
LPI+STL+ L+ TGD+I++IEGIFSGTLSYIFN N K G A FS++V AK+ GYTE
Sbjct: 157 LPIISTLKELIATGDEIIKIEGIFSGTLSYIFNVWSPNGKKGTASFSDIVKIAKQNGYTE 216
Query: 789 PDPRDDLSGTDVARKVIILARESGLKLE-LSNIPIESLVPEPLRACASAQEFMQQLPKFD 847
PDPRDDL+G DVARKV IL+R +G+ +E S+ P++SL+PEPL++ +A+EF+ LP FD
Sbjct: 217 PDPRDDLNGMDVARKVTILSRIAGVHVESASSFPVKSLIPEPLKSAVNAEEFLAGLPNFD 276
Query: 848 QEFAKKQEDADNAGEVLRYVGVVDVTNKKGVVELRKYKKDHPFAQLSGSDNIIAFTTRRY 907
EFA +E+A+ G+V+R+VG DV NK +V+L KY HPFA L SDNII+FTT+RY
Sbjct: 277 SEFASMREEAEKEGKVVRFVGEADVANKTTLVKLEKYDASHPFANLQSSDNIISFTTKRY 336
Query: 908 KNQPLIVRGPGAGAQVTAGGIFSDILRLASYLGA 941
+PL+V G GAGA VTA G+ D++++ S + A
Sbjct: 337 HTRPLVVIGAGAGAAVTAAGVLGDMIKIMSQVRA 370
>AK_METJA (Q57991) Probable aspartokinase (EC 2.7.2.4) (Aspartate
kinase)
Length = 473
Score = 269 bits (687), Expect = 3e-71
Identities = 172/474 (36%), Positives = 261/474 (54%), Gaps = 19/474 (4%)
Query: 88 SVHKFGGTCMGSSQRIKNVGDIVLNDDSERK--LVVVSAMSKVTDMMYDLINKAQS-RDE 144
+V KFGGT +GS +RI++V IV E +VVVSAMS+VT+ + ++ +A RD
Sbjct: 3 TVMKFGGTSVGSGERIRHVAKIVTKRKKEDDDVVVVVSAMSEVTNALVEISQQALDVRDI 62
Query: 145 SYISS-LDAVLEKHSATAHDILDGETLAIFLSKLHED-ISNLKAMLRAIYIAGHVTESFT 202
+ + + + EKH + + E + + K+ + I L+ +L + G +T
Sbjct: 63 AKVGDFIKFIREKHYKAIEEAIKSEEIKEEVKKIIDSRIEELEKVLIGVAYLGELTPKSR 122
Query: 203 DFVVGHGELWSAQMLSLVIRKNGIDCKWMDTREVLIVNPTSSNQVDPDYLESERRLEKWY 262
D+++ GE S+ +LS IR G ++ E I+ + LE + RL
Sbjct: 123 DYILSFGERLSSPILSGAIRDLGEKSIALEGGEAGIITDNNFGSARVKRLEVKERLLPL- 181
Query: 263 SLNPCKVIIATGFIASTPENIPTTLKRDGSDFSAAIMGSLFRARQVTIWTDVDGVYSADP 322
L + + TGFI +T E TTL R GSD+SAA++G A + IWTDV GVY+ DP
Sbjct: 182 -LKEGIIPVVTGFIGTTEEGYITTLGRGGSDYSAALIGYGLDADIIEIWTDVSGVYTTDP 240
Query: 323 RKVSEAVILKTLSYQEAWEMSYFGANVLHPRTIIPVMRYGIPILIRNIFNLSAPGTKICH 382
R V A + LSY EA E++YFGA VLHPRTI P M GIPIL++N F + GT I +
Sbjct: 241 RLVPTARRIPKLSYIEAMELAYFGAKVLHPRTIEPAMEKGIPILVKNTFEPESEGTLITN 300
Query: 383 PVVSDYEDKSNLQNYVKGFATIDNLALVNVEGTGMAGVPGTASAIFAAVKDVGANVIMIS 442
D + VK +TI N+AL+N+ G GM GV GTA+ IF A+ + NVI+IS
Sbjct: 301 -------DMEMSDSIVKAISTIKNVALINIFGAGMVGVSGTAARIFKALGEEEVNVILIS 353
Query: 443 QASSEHSVCFAVPEKEVKAVAEALQSRF-----RQALDNGRLSQVAVIPNCSILAAVGQK 497
Q SSE ++ V E++V +AL+ F + L+N + V+V + +++ VG
Sbjct: 354 QGSSETNISLVVSEEDVDKALKALKREFGDFGKKSFLNNNLIRDVSVDKDVCVISVVGAG 413
Query: 498 MASTPGVSATLFNALAKANINVRAIAQGCSEYNITVVIKREDSIKALRAVHSRF 551
M G++ +F A++++ N++ IAQG SE NI+ VI +D + +R +H +F
Sbjct: 414 MRGAKGIAGKIFTAVSESGANIKMIAQGSSEVNISFVIDEKDLLNCVRKLHEKF 467
Score = 55.5 bits (132), Expect = 7e-07
Identities = 42/158 (26%), Positives = 74/158 (46%), Gaps = 30/158 (18%)
Query: 482 VAVIPNCSILAAVGQKMASTPGVSATLFNALAKANINVRAIAQGCSEYNITVVIKREDSI 541
++ I N +++ G M G +A +F AL + +NV I+QG SE NI++V+ ED
Sbjct: 312 ISTIKNVALINIFGAGMVGVSGTAARIFKALGEEEVNVILISQGSSETNISLVVSEEDVD 371
Query: 542 KALRAVHSRF-------YLSRTTI----------AMGIIGPGLIGS--------TLLDQL 576
KAL+A+ F +L+ I + ++G G+ G+ T + +
Sbjct: 372 KALKALKREFGDFGKKSFLNNNLIRDVSVDKDVCVISVVGAGMRGAKGIAGKIFTAVSES 431
Query: 577 RDQAK-----HSHLYISYLLHTRRLLEICGKLMQQFIQ 609
K S + IS+++ + LL KL ++FI+
Sbjct: 432 GANIKMIAQGSSEVNISFVIDEKDLLNCVRKLHEKFIE 469
>DHOM_YEAST (P31116) Homoserine dehydrogenase (EC 1.1.1.3) (HDH)
Length = 359
Score = 252 bits (643), Expect = 4e-66
Identities = 152/393 (38%), Positives = 226/393 (56%), Gaps = 40/393 (10%)
Query: 553 LSRTTIAMGIIGPGLIGSTLLDQLRDQAKHSHLYISYLLHTRRLLEICGKLMQQFIQCRL 612
+S + + +IG G++GS LDQL + L R L + + F
Sbjct: 1 MSTKVVNVAVIGAGVVGSAFLDQLLAMKSTITYNLVLLAEAERSL-----ISKDFSP--- 52
Query: 613 QF*KKNLTLICV*WA*LAQSQCFSVMSKWKE-LREERGEVANLEKFAQHVHGNNFIPNTA 671
+V S WK L + L+ H+ +
Sbjct: 53 ----------------------LNVGSDWKAALAASTTKTLPLDDLIAHLKTSP--KPVI 88
Query: 672 LVDCTADSIIAGHYYEWLCKGIHVITPNKKANSGPLEQYLRLRALQRQSYTHYFYEATVG 731
LVD T+ + IAG Y +++ GI + TPNKKA S L + L + + + ++EATVG
Sbjct: 89 LVDNTSSAYIAGFYTKFVENGISIATPNKKAFSSDLATWKALFS-NKPTNGFVYHEATVG 147
Query: 732 AGLPIVSTLRGLLETGDKILQIEGIFSGTLSYIFNNFKDGRA----FSEVVGEAKEAGYT 787
AGLPI+S LR +++TGD++ +IEGIFSGTLSYIFN F +A FS+VV AK+ GYT
Sbjct: 148 AGLPIISFLREIIQTGDEVEKIEGIFSGTLSYIFNEFSTSQANDVKFSDVVKVAKKLGYT 207
Query: 788 EPDPRDDLSGTDVARKVIILARESGLKLEL-SNIPIESLVPEPLRACASAQEFMQQLPKF 846
EPDPRDDL+G DVARKV I+ R SG+++E ++ P++SL+P+PL + SA EF+++L +
Sbjct: 208 EPDPRDDLNGLDVARKVTIVGRISGVEVESPTSFPVQSLIPKPLESVKSADEFLEKLSDY 267
Query: 847 DQEFAKKQEDADNAGEVLRYVGVVDVTNKKGVVELRKYKKDHPFAQLSGSDNIIAFTTRR 906
D++ + +++A +VLR++G VDV K V + KY HPFA L GSDN+I+ T+R
Sbjct: 268 DKDLTQLKKEAATENKVLRFIGKVDVATKSVSVGIEKYDYSHPFASLKGSDNVISIKTKR 327
Query: 907 YKNQPLIVRGPGAGAQVTAGGIFSDILRLASYL 939
Y N P++++G GAGA VTA G+ D++++A L
Sbjct: 328 YTN-PVVIQGAGAGAAVTAAGVLGDVIKIAQRL 359
>AK2H_ECOLI (P00562) Bifunctional aspartokinase/homoserine
dehydrogenase II (AKII-HDII) [Includes: Aspartokinase II
(EC 2.7.2.4); Homoserine dehydrogenase II (EC 1.1.1.3)]
Length = 809
Score = 216 bits (551), Expect = 2e-55
Identities = 118/268 (44%), Positives = 163/268 (60%), Gaps = 2/268 (0%)
Query: 672 LVDCTADSIIAGHYYEWLCKGIHVITPNKKANSGPLEQYLRLRALQRQSYTHYFYEATVG 731
++D TA +A Y ++ G HVI+ NK A + +Y ++ ++ H+ Y ATVG
Sbjct: 544 VLDVTASQQLADQYLDFASHGFHVISANKLAGASDSNKYRQIHDAFEKTGRHWLYNATVG 603
Query: 732 AGLPIVSTLRGLLETGDKILQIEGIFSGTLSYIFNNFKDGRAFSEVVGEAKEAGYTEPDP 791
AGLPI T+R L+++GD IL I GIFSGTLS++F F F+E+V +A + G TEPDP
Sbjct: 604 AGLPINHTVRDLIDSGDTILSISGIFSGTLSWLFLQFDGSVPFTELVDQAWQQGLTEPDP 663
Query: 792 RDDLSGTDVARKVIILARESGLKLELSNIPIESLVPEPLRACASAQEFMQQLPKFDQEFA 851
RDDLSG DV RK++ILARE+G +E + +ESLVP S F + + +++
Sbjct: 664 RDDLSGKDVMRKLVILAREAGYNIEPDQVRVESLVPAHCEG-GSIDHFFENGDELNEQMV 722
Query: 852 KKQEDADNAGEVLRYVGVVDVTNKKGVVELRKYKKDHPFAQLSGSDNIIAFTTRRYKNQP 911
++ E A G VLRYV D N K V + ++DHP A L DN+ A +R Y++ P
Sbjct: 723 QRLEAAREMGLVLRYVARFD-ANGKARVGVEAVREDHPLASLLPCDNVFAIESRWYRDNP 781
Query: 912 LIVRGPGAGAQVTAGGIFSDILRLASYL 939
L++RGPGAG VTAG I SDI RLA L
Sbjct: 782 LVIRGPGAGRDVTAGAIQSDINRLAQLL 809
Score = 142 bits (357), Expect = 5e-33
Identities = 93/293 (31%), Positives = 147/293 (49%), Gaps = 9/293 (3%)
Query: 89 VHKFGGTCMGSSQRIKNVGDIVLNDDSERKLVVVSAMSKVTDMMYDLINKAQSRDESYIS 148
+HKFGG+ + + V I+ ++VVSA T+ + + + +Q+ D
Sbjct: 13 LHKFGGSSLADVKCYLRVAGIMAEYSQPDDMMVVSAAGSTTNQLINWLKLSQT-DRLSAH 71
Query: 149 SLDAVLEKHSATA-HDILDGETLAIFLSKLHEDISNLKAMLRAIYIAGHVTESFTDFVVG 207
+ L ++ +L E +S D+ L A+L + + ++ VVG
Sbjct: 72 QVQQTLRRYQCDLISGLLPAEEADSLISAFVSDLERLAALLDS-----GINDAVYAEVVG 126
Query: 208 HGELWSAQMLSLVIRKNGIDCKWMDTREVLIVNPTSSNQVDPDYLESERRLEKWYSLNPC 267
HGE+WSA+++S V+ + G+ W+D RE L + QVD S L++ +P
Sbjct: 127 HGEVWSARLMSAVLNQQGLPAAWLDAREFLRAERAAQPQVDEGL--SYPLLQQLLVQHPG 184
Query: 268 KVIIATGFIASTPENIPTTLKRDGSDFSAAIMGSLFRARQVTIWTDVDGVYSADPRKVSE 327
K ++ TGFI+ L R+GSD+SA +G+L +VTIW+DV GVYSADPRKV +
Sbjct: 185 KRLVVTGFISRNNAGETVLLGRNGSDYSATQIGALAGVSRVTIWSDVAGVYSADPRKVKD 244
Query: 328 AVILKTLSYQEAWEMSYFGANVLHPRTIIPVMRYGIPILIRNIFNLSAPGTKI 380
A +L L EA E++ A VLH RT+ PV I + +R + T+I
Sbjct: 245 ACLLPLLRLDEASELARLAAPVLHARTLQPVSGSEIDLQLRCSYTPDQGSTRI 297
>AK_SCHPO (O60163) Probable aspartokinase (EC 2.7.2.4) (Aspartate
kinase)
Length = 519
Score = 176 bits (446), Expect = 3e-43
Identities = 140/503 (27%), Positives = 237/503 (46%), Gaps = 51/503 (10%)
Query: 78 EKELSKGDSWSVHKFGGTCMGSSQRIKNVGDIVLNDDSERKLVVVSAMSKVTDMMYDLIN 137
E + SKG W V KFGGT +G IK D+ S +++ +V + ++ TD
Sbjct: 8 ENDPSKG--WVVQKFGGTSVGKFP-IKIAVDVAKEYLSTKRVALVCS-ARSTD------T 57
Query: 138 KAQSRDESYISSLDAVLEKHSATAHDIL----------------DGETLAIFLSKLHEDI 181
KA+ I + +A L + HD++ D + H D
Sbjct: 58 KAEGTTTRLIRATEAALRPAVGSVHDLVRIIETDHVQAARDFIQDVGIQDELIDAFHADC 117
Query: 182 SNLKAMLRAIYIAGHVTESFTDFVVGHGELWSAQMLSLVIRKNGIDCKWMDTREVLIVNP 241
L+ L AI + V+ D V+G GE S + ++ V++ GID +++D ++
Sbjct: 118 VELEQYLNAIRVLSEVSPRTRDLVIGMGERLSCRFMAAVLKDQGIDSEFIDMSHIIDEQR 177
Query: 242 TSSNQVDPDYLESERRLEKWYSLNPCKVIIATGFIASTPENIPTTLKRDGSDFSAAIMGS 301
N Y +L + KV + TGF P + + + R +DF AA++
Sbjct: 178 EWRNLDASFYAYLASQLASKVTAVGNKVPVVTGFFGMVPGGLLSQIGRGYTDFCAALLAV 237
Query: 302 LFRARQVTIWTDVDGVYSADPRKVSEAVILKTLSYQEAWEMSYFGANVLHPRTIIPVMRY 361
A ++ IW +VDG+++ADPRKV A +L ++ +EA E++Y+G+ V+HP T+ V+
Sbjct: 238 GLNADELQIWKEVDGIFTADPRKVPTARLLPLITPEEAAELTYYGSEVIHPFTMSQVVHA 297
Query: 362 GIPILIRNIFNLSAPGTKICHPVVSDY--------------EDKSNLQNYVKGFATI-DN 406
IPI I+N+ N GT I +S + + ++L N TI D
Sbjct: 298 RIPIRIKNVGNPRGKGTVIFPDTISRHGSATPPHPPKIMPDDISASLANKGATAVTIKDT 357
Query: 407 LALVNVEGTGMAGVPGTASAIFAAVKDVGANVIMISQASSEHSVCFAVPEKEVKAVAEAL 466
+ ++N++ G ++IFA + V +I+ +SE V A+ E E+
Sbjct: 358 IMVINIQSNRKISAHGFLASIFAILDKYKLAVDLIT--TSEVHVSMALYE-------ESD 408
Query: 467 QSRFRQA-LDNGRLSQVAVIPNCSILAAVGQKMASTPGVSATLFNALAKANINVRAIAQG 525
+A ++ RL + ++ +IL+ VG+ M +T G + +F LA+A IN+ I+QG
Sbjct: 409 DGNMHEAFVELRRLGTLDILHGLAILSLVGKHMRNTTGYAGRMFCKLAEAQINIEMISQG 468
Query: 526 CSEYNITVVIKREDSIKALRAVH 548
SE NI+ VI + ++KAL +H
Sbjct: 469 ASEINISCVIDEKMAVKALNVIH 491
>AK3_ECOLI (P08660) Lysine-sensitive aspartokinase III (EC 2.7.2.4)
(Aspartate kinase III)
Length = 449
Score = 174 bits (440), Expect = 1e-42
Identities = 130/466 (27%), Positives = 225/466 (47%), Gaps = 25/466 (5%)
Query: 89 VHKFGGTCMGSSQRIKNVGDIVLNDDSERKLVVVSAMSKVTDMMYDLINKAQSRDESYIS 148
V KFGGT + + DIVL+D + R LVV+SA + +T+++ L + +
Sbjct: 6 VSKFGGTSVADFDAMNRSADIVLSDANVR-LVVLSASAGITNLLVALAEGLEPGER--FE 62
Query: 149 SLDAVLEKHSATAHDILDGETLAIFLSKLHEDISNLKAMLRAIYIAGHVTESFTDFVVGH 208
LDA+ A + + + +L E N+ + A +A + + TD +V H
Sbjct: 63 KLDAIRNIQFAILERLRYPNVIREEIERLLE---NITVLAEAAALA--TSPALTDELVSH 117
Query: 209 GELWSAQMLSLVIRKNGIDCKWMDTREVLIVNPTSSNQVDPDY--LESERRLEKWYSLNP 266
GEL S + ++R+ + +W D R+V+ N + +PD L L+ LN
Sbjct: 118 GELMSTLLFVEILRERDVQAQWFDVRKVMRTNDRFG-RAEPDIAALAELAALQLLPRLNE 176
Query: 267 CKVIIATGFIASTPENIPTTLKRDGSDFSAAIMGSLFRARQVTIWTDVDGVYSADPRKVS 326
++I GFI S + TTL R GSD++AA++ A +V IWTDV G+Y+ DPR VS
Sbjct: 177 -GLVITQGFIGSENKGRTTTLGRGGSDYTAALLAEALHASRVDIWTDVPGIYTTDPRVVS 235
Query: 327 EAVILKTLSYQEAWEMSYFGANVLHPRTIIPVMRYGIPILIRNIFNLSAPGTKICHPVVS 386
A + +++ EA EM+ FGA VLHP T++P +R IP+ + + + A GT +C
Sbjct: 236 AAKRIDEIAFAEAAEMATFGAKVLHPATLLPAVRSDIPVFVGSSKDPRAGGTLVC----- 290
Query: 387 DYEDKSNLQNYVKGFATIDNLALVNVEGTGMAGVPGTASAIFAAVKDVGANVIMISQASS 446
+K+ + A N L+ + M G + +F + +V +I+ +S
Sbjct: 291 ---NKTENPPLFRALALRRNQTLLTLHSLNMLHSRGFLAEVFGILARHNISVDLIT--TS 345
Query: 447 EHSVCFAVPEKEVKAVAEALQSRFRQALDNGRLSQVAVIPNCSILAAVGQKMASTPGVSA 506
E SV + + + L ++ ++ L +V V +++A +G ++ GV
Sbjct: 346 EVSVALTLDTTGSTSTGDTLLTQ-SLLMELSALCRVEVEEGLALVALIGNDLSKACGVGK 404
Query: 507 TLFNALAKANINVRAIAQGCSEYNITVVIKREDSIKALRAVHSRFY 552
+F L N+R I G S +N+ ++ ED+ + ++ +HS +
Sbjct: 405 EVFGVLEP--FNIRMICYGASSHNLCFLVPGEDAEQVVQKLHSNLF 448
>AK_YEAST (P10869) Aspartokinase (EC 2.7.2.4) (Aspartate kinase)
Length = 527
Score = 169 bits (429), Expect = 2e-41
Identities = 137/508 (26%), Positives = 242/508 (46%), Gaps = 44/508 (8%)
Query: 82 SKGDSWSVHKFGGTCMGSSQRIKNVGDIVLN----DDSERKLVVV----SAMSKVTDMMY 133
S +W V KFGGT +G ++ V DIV + D + VV S+ +K
Sbjct: 9 SSHSNWVVQKFGGTSVGKFP-VQIVDDIVKHYSKPDGPNNNVAVVCSARSSYTKAEGTTS 67
Query: 134 DLINKAQ--SRDESYISSLDAVLEKHSATAHD-ILDGETLAIFLSKLHEDISNLKAMLRA 190
L+ S++ + ++ + + H A IL+ A + ++++ +K L A
Sbjct: 68 RLLKCCDLASQESEFQDIIEVIRQDHIDNADRFILNPALQAKLVDDTNKELELVKKYLNA 127
Query: 191 IYIAGHVTESFTDFVVGHGELWSAQMLSLVIRKNGIDCKWMDTREVLIVNPTSSNQVDPD 250
+ G V+ D V+ GE S ++ + G K++D + + + S++ +D
Sbjct: 128 SKVLGEVSSRTVDLVMSCGEKLSCLFMTALCNDRGCKAKYVDLSHI-VPSDFSASALDNS 186
Query: 251 YLES-----ERRLEKWYSLNPCKVIIATGFIASTPENIPTTLKRDGSDFSAAIMGSLFRA 305
+ + +L + S V + TGF P + + R +D AA++ A
Sbjct: 187 FYTFLVQALKEKLAPFVSAKERIVPVFTGFFGLVPTGLLNGVGRGYTDLCAALIAVAVNA 246
Query: 306 RQVTIWTDVDGVYSADPRKVSEAVILKTLSYQEAWEMSYFGANVLHPRTIIPVMRYGIPI 365
++ +W +VDG+++ADPRKV EA +L +++ +EA E++Y+G+ V+HP T+ V+R IPI
Sbjct: 247 DELQVWKEVDGIFTADPRKVPEARLLDSVTPEEASELTYYGSEVIHPFTMEQVIRAKIPI 306
Query: 366 LIRNIFNLSAPGTKIC-------------HP---VVSDYEDKSNLQNYVKGFATIDNLAL 409
I+N+ N GT I HP + S + +K + T +++ +
Sbjct: 307 RIKNVQNPLGNGTIIYPDNVAKKGESTPPHPPENLSSSFYEKR--KRGATAITTKNDIFV 364
Query: 410 VNVEGTGMAGVPGTASAIFAAVKDVGANVIMISQASSEHSVCFAVPEKEVKAVAEALQSR 469
+N+ G + IF + V +IS + S+ +P+ A++L+S
Sbjct: 365 INIHSNKKTLSHGFLAQIFTILDKYKLVVDLISTSEVHVSMALPIPD------ADSLKS- 417
Query: 470 FRQALDNGR-LSQVAVIPNCSILAAVGQKMASTPGVSATLFNALAKANINVRAIAQGCSE 528
RQA + R L V + SI++ VG+ M G++ T+F LA+ IN+ I+QG +E
Sbjct: 418 LRQAEEKLRILGSVDITKKLSIVSLVGKHMKQYIGIAGTMFTTLAEEGINIEMISQGANE 477
Query: 529 YNITVVIKREDSIKALRAVHSRFYLSRT 556
NI+ VI DSIKAL+ +H++ RT
Sbjct: 478 INISCVINESDSIKALQCIHAKLLSERT 505
>AK_THETH (P61489) Aspartokinase (EC 2.7.2.4) (Aspartate kinase)
[Contains: Aspartokinase alpha subunit (ASK-alpha);
Aspartokinase beta subunit (ASK-beta)]
Length = 405
Score = 142 bits (358), Expect = 4e-33
Identities = 121/415 (29%), Positives = 192/415 (46%), Gaps = 29/415 (6%)
Query: 147 ISSLDAVLEKHSATAHDILDGETLAIFLSKLHEDISNLKAMLRAIYIAGHVTESFTDFVV 206
+ L+ + + AH G LA+ +S + L A+ + + E D +
Sbjct: 13 VGDLERIHKVAQRIAHYREKGHRLAVVVSAMGHTTDELIALAKRVNPRPPFRE--LDLLT 70
Query: 207 GHGELWSAQMLSLVIRKNGIDCKWMDTREVLIVNPTSSNQVDPDYLE-SERRLEKWYSLN 265
GE S +LS+ + GI K ++ I T D LE + R+ + +L+
Sbjct: 71 TTGEQVSVALLSMQLWAMGIPAKGFVQHQIGIT--TDGRYGDARILEVNPARIRE--ALD 126
Query: 266 PCKVIIATGFIASTPENIPTTLKRDGSDFSAAIMGSLFRARQVTIWTDVDGVYSADPRKV 325
V + GF+ +TPE TTL R GSD +A + + A++ I+TD +GVY+ DP +
Sbjct: 127 QGFVAVIAGFMGTTPEGEITTLGRGGSDTTAVAIAAALGAKECEIYTDTEGVYTTDPHLI 186
Query: 326 SEAVILKTLSYQEAWEMSYFGANVLHPRTIIPVMRYGIPILIRNIFNLSAPGTKICHPVV 385
EA L + Y + EM+ GA VLHPR + RYG+ + +R+ F+ + PGT +
Sbjct: 187 PEARKLSVIGYDQMLEMAALGARVLHPRAVYYAKRYGVVLHVRSSFSYN-PGTLV----- 240
Query: 386 SDYEDKSNLQNYVKGFATIDNLALVNVEGTGMAGVPGTASAIFAAVKDVGANVIMISQA- 444
E + V G A +L + G+ PG A+ +F A+ + G V MI Q
Sbjct: 241 --KEVAMEMDKAVTGVAL--DLDHAQIGLIGIPDQPGIAAKVFQALAERGIAVDMIIQGV 296
Query: 445 ----SSEHSVCFAVPEKEVKAVAEALQSRFRQALDNGRLSQVAVIPNCSILAAVGQKMAS 500
S + F V + + EAL+ + + + P+ + ++ VG +AS
Sbjct: 297 PGHDPSRQQMAFTVKKDFAQEALEALEPVLAEI-----GGEAILRPDIAKVSIVGVGLAS 351
Query: 501 TPGVSATLFNALAKANINVRAIAQGCSEYNITVVIKREDSIKALRAVHSRFYLSR 555
TP V A +F A+A N+ IA SE I+V+I E + ALRAVH F L +
Sbjct: 352 TPEVPAKMFQAVASTGANIEMIA--TSEVRISVIIPAEYAEAALRAVHQAFELDK 404
>AK_THET2 (P61488) Aspartokinase (EC 2.7.2.4) (Aspartate kinase)
[Contains: Aspartokinase alpha subunit (ASK-alpha);
Aspartokinase beta subunit (ASK-beta)]
Length = 405
Score = 142 bits (358), Expect = 4e-33
Identities = 133/474 (28%), Positives = 207/474 (43%), Gaps = 81/474 (17%)
Query: 89 VHKFGGTCMGSSQRIKNVGDIVLN--DDSERKLVVVSAMSKVTDMMYDLINKAQSRDESY 146
V K+GGT +G +RI V + + + R VVVSAM TD + L + R
Sbjct: 5 VQKYGGTSVGDLERIHKVAQRIAHYREKGHRLAVVVSAMGHTTDELIALAKRVNPRPP-- 62
Query: 147 ISSLDAVLEKHSATAHDILDGETLAIFLSKLHEDISNLKAMLRAIYIAGHVTESFTDFVV 206
LD + GE +++ L + ++ G + F +
Sbjct: 63 FRELDLL----------TTTGEQVSVALLSMQ------------LWAMGIPAKGFVQHQI 100
Query: 207 GHGELWSAQMLSLVIRKNGIDCKWMDTREVLIVNPTSSNQVDPDYLESERRLEKWYSLNP 266
G I +G ++ D R +L VNP + LE+ +
Sbjct: 101 G-------------ITTDG---RYGDAR-ILEVNPARIREA----------LEQGF---- 129
Query: 267 CKVIIATGFIASTPENIPTTLKRDGSDFSAAIMGSLFRARQVTIWTDVDGVYSADPRKVS 326
V + GF+ +TPE TTL R GSD +A + + A++ I+TD +GVY+ DP +
Sbjct: 130 --VAVIAGFMGTTPEGEITTLGRGGSDTTAVAIAAALGAKECEIYTDTEGVYTTDPHLIP 187
Query: 327 EAVILKTLSYQEAWEMSYFGANVLHPRTIIPVMRYGIPILIRNIFNLSAPGTKICHPVVS 386
EA L + Y + EM+ GA VLHPR + RYG+ + +R+ F+ + PGT +
Sbjct: 188 EARKLSVIGYDQMLEMAALGARVLHPRAVYYAKRYGVVLHVRSSFSYN-PGTLV------ 240
Query: 387 DYEDKSNLQNYVKGFATIDNLALVNVEGTGMAGVPGTASAIFAAVKDVGANVIMISQA-- 444
E + V G A +L + G+ PG A+ +F A+ + G V MI Q
Sbjct: 241 -KEVAMEMDKAVTGVAL--DLDHAQIGLIGIPDQPGIAAKVFQALAERGIAVDMIIQGVP 297
Query: 445 ---SSEHSVCFAVPEKEVKAVAEALQSRFRQALDNGRLSQVAVIPNCSILAAVGQKMAST 501
S + F V + + EAL+ + + + P+ + ++ VG +AST
Sbjct: 298 GHDPSRQQMAFTVKKDFAQEALEALEPVLAEI-----GGEAILRPDIAKVSIVGVGLAST 352
Query: 502 PGVSATLFNALAKANINVRAIAQGCSEYNITVVIKREDSIKALRAVHSRFYLSR 555
P V A +F A+A N+ IA SE I+V+I E + ALRAVH F L +
Sbjct: 353 PEVPAKMFQAVASTGANIEMIA--TSEVRISVIIPAEYAEAALRAVHQAFELDK 404
>AK2_BACSU (P08495) Aspartokinase 2 (EC 2.7.2.4) (Aspartokinase II)
(Aspartate kinase 2) [Contains: Aspartokinase II alpha
subunit; Aspartokinase II beta subunit]
Length = 408
Score = 141 bits (356), Expect = 7e-33
Identities = 132/475 (27%), Positives = 218/475 (45%), Gaps = 84/475 (17%)
Query: 89 VHKFGGTCMGSSQRIKNVGD--IVLNDDSERKLVVVSAMSKVTDMMYDLINKAQSRDESY 146
V KFGGT +GS ++I+N + I + +VVVSAM +S DE
Sbjct: 5 VQKFGGTSVGSVEKIQNAANRAIAEKQKGHQVVVVVSAMG-------------KSTDE-L 50
Query: 147 ISSLDAVLEKHSATAHDIL--DGETLAIFLSKLHEDISNLKAMLRAIYIAGHVTESFTDF 204
+S A+ ++ S D+L GE + I L + A+ G+ S+T
Sbjct: 51 VSLAKAISDQPSKREMDMLLATGEQVTISLLSM------------ALQEKGYDAVSYTG- 97
Query: 205 VVGHGELWSAQMLSLVIRKNGIDCKWMDTREVLIVNPTSSNQVDPDYLESERRLEKWYSL 264
W A + + I N +D L + LEK
Sbjct: 98 -------WQAGIRTEAIHGNA-----------------RITDIDTSVLADQ--LEKG--- 128
Query: 265 NPCKVIIATGFIASTPENIPTTLKRDGSDFSAAIMGSLFRARQVTIWTDVDGVYSADPRK 324
K++I GF T + TTL R GSD +A + + +A + I+TDV GV++ DPR
Sbjct: 129 ---KIVIVAGFQGMTEDCEITTLGRGGSDTTAVALAAALKADKCDIYTDVPGVFTTDPRY 185
Query: 325 VSEAVILKTLSYQEAWEMSYFGANVLHPRTIIPVMRYGIPILIRNIFNLSAPGTKICHPV 384
V A L+ +SY E E++ GA VLHPR + Y +P+ +R+ A GT I
Sbjct: 186 VKSARKLEGISYDEMLELANLGAGVLHPRAVEFAKNYQVPLEVRSSTETEA-GTLI---- 240
Query: 385 VSDYEDKSNLQN--YVKGFATIDNLALVNVEGTGMAGVPGTASAIFA--AVKDVGANVIM 440
E++S+++ V+G A D + V + G+ T S IF A +++ ++I+
Sbjct: 241 ----EEESSMEQNLIVRGIAFEDQITRVTI--YGLTSGLTTLSTIFTTLAKRNINVDIII 294
Query: 441 ISQASSEHSVCFAVPEKEVKAVAEALQSRFRQALDNGRLSQVAVIPNCSILAAVGQKMAS 500
+QA + + F+V ++ L+ ++ AL+ ++ + + SI VG M S
Sbjct: 295 QTQAEDKTGISFSVKTEDADQTVAVLE-EYKDALEFEKIETESKLAKVSI---VGSGMVS 350
Query: 501 TPGVSATLFNALAKANINVRAIAQGCSEYNITVVIKREDSIKALRAVHSRFYLSR 555
PGV+A +F LA+ NI ++ ++ SE ++ V+ D +KA+ ++H F LS+
Sbjct: 351 NPGVAAEMFAVLAQKNILIKMVS--TSEIKVSTVVSENDMVKAVESLHDAFELSK 403
>AK3_BACSU (P94417) Probable aspartokinase (EC 2.7.2.4) (Aspartate
kinase)
Length = 454
Score = 141 bits (355), Expect = 9e-33
Identities = 119/475 (25%), Positives = 226/475 (47%), Gaps = 40/475 (8%)
Query: 89 VHKFGGTCMGSSQRIKNVGDIVLNDDSERKLVVVSAM-------SKVTDMMYDLINKAQS 141
V KFGG+ + S ++ V IV +D + RK VVVSA +KVTD++ + +
Sbjct: 3 VVKFGGSSLASGAQLDKVFHIVTSDPA-RKAVVVSAPGKHYAEDTKVTDLLIACAEQYLA 61
Query: 142 RDESYISSLDAVLEKHSATAHDILDGETLAIFLSKLHEDISNLKAMLRAIYIAGHVT--E 199
S +AV+E+++ A+++ G+++ + K+ +D+ L + G + E
Sbjct: 62 TG-SAPELAEAVVERYALIANELQLGQSI---IEKIRDDLFTL--------LEGDKSNPE 109
Query: 200 SFTDFVVGHGELWSAQMLSLVIRKNGIDCKWMDTRE--VLIVNPTSSNQVDPDYLESERR 257
+ D V GE +A++++ R G+ ++++ ++ + + N + QV P+ ++ R
Sbjct: 110 QYLDAVKASGEDNNAKLIAAYFRYKGVKAEYVNPKDAGLFVTNEPGNAQVLPESYQNLYR 169
Query: 258 LEKWYSLNPCKVIIATGFIASTPENIPTTLKRDGSDFSAAIMGSLFRARQVTIWTDVDGV 317
L + L II GF + + T R GSD + +I+ + +A +TDVD V
Sbjct: 170 LRERDGL-----IIFPGFFGFSKDGDVITFSRSGSDITGSILANGLQADLYENFTDVDAV 224
Query: 318 YSADPRKVSEAVILKTLSYQEAWEMSYFGANVLHPRTIIPVMRYGIPILIRNIFNLSAPG 377
YS +P V + L+Y+E E+SY G +V H +IP R GIP+ I+N N SA G
Sbjct: 225 YSVNPSFVENPKEISELTYREMRELSYAGFSVFHDEALIPAFRAGIPVQIKNTNNPSAEG 284
Query: 378 TKICHPVVSDYEDKSNLQNYVKGFATIDNLALVNVEGTGMAGVPGTASAIFAAVKDVGAN 437
T++ + N V G A+ + + M G +++ G
Sbjct: 285 TRV-------VSKRDNTNGPVVGIASDTGFCSIYISKYLMNREIGFGRRALQILEEHGLT 337
Query: 438 VIMISQASSEHSVCFAVPEKEVKAVAEALQSRFRQALDNGRLSQVAVIPNCSILAAVGQK 497
+ + ++ + + ++ A E +S ++ ++ +V V + +++ VG+
Sbjct: 338 YEHVPSGIDDMTI--ILRQGQMDAATE--RSVIKRIEEDLHADEVIVEHHLALIMVVGEA 393
Query: 498 MASTPGVSATLFNALAKANINVRAIAQGCSEYNITVVIKREDSIKALRAVHSRFY 552
M G +A AL++A +N+ I QG SE ++ +K + KA++A++ F+
Sbjct: 394 MRHNVGTTARAAKALSEAQVNIEMINQGSSEVSMMFGVKEAEERKAVQALYQEFF 448
Database: sprot
Posted date: Nov 25, 2004 10:54 AM
Number of letters in database: 59,974,054
Number of sequences in database: 164,201
Lambda K H
0.321 0.135 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 105,171,582
Number of Sequences: 164201
Number of extensions: 4384299
Number of successful extensions: 11717
Number of sequences better than 10.0: 180
Number of HSP's better than 10.0 without gapping: 135
Number of HSP's successfully gapped in prelim test: 45
Number of HSP's that attempted gapping in prelim test: 11387
Number of HSP's gapped (non-prelim): 224
length of query: 942
length of database: 59,974,054
effective HSP length: 120
effective length of query: 822
effective length of database: 40,269,934
effective search space: 33101885748
effective search space used: 33101885748
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 71 (32.0 bits)
Medicago: description of AC146585.12