BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC146574.12 - phase: 0 /pseudo
         (951 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

YQD3_CAEEL (Q09263) Hypothetical protein C32D5.3 in chromosome II      81  2e-14
Y143_HUMAN (Q14156) Hypothetical protein KIAA0143 (Fragment)           76  5e-13
REST_HUMAN (P30622) Restin (Cytoplasmic linker protein-170 alpha...    35  1.2
FSHR_RAT (P20395) Follicle stimulating hormone receptor precurso...    33  4.7
FSHR_MOUSE (P35378) Follicle stimulating hormone receptor precur...    33  4.7
YE38_SCHPO (O13892) Hypothetical protein C20G4.08 in chromosome I      32  6.1
PS12_MOUSE (Q80ZC9) Psoriasis susceptibility 1 candidate gene 2 ...    32  6.1
IF2P_YEAST (P39730) Eukaryotic translation initiation factor 5B ...    32  8.0

>YQD3_CAEEL (Q09263) Hypothetical protein C32D5.3 in chromosome II
          Length = 859

 Score = 80.9 bits (198), Expect = 2e-14
 Identities = 91/373 (24%), Positives = 161/373 (42%), Gaps = 39/373 (10%)

Query: 32  RYKKLIAEILPRNKVAELNDRKIGKLCEYASKNPLRIPKITENLEQRCYKDLRNESFGSV 91
           RY++L+  I PR     L    + KL  YA  +P ++ +I E L  R  +DL  +    V
Sbjct: 13  RYRRLVDSIYPRAVTDGLLYSNMQKLTFYAISHPEKLERIGEYLVMRMVRDLSRQRPVQV 72

Query: 92  KVILCIYRKLLSSCRE--QIPLFASSLLGIIRTLLEQTRADEVRILGCNTLVDFI-IFQT 148
           K+ +    +LL +C     +P F+ + L +++ LLE   A ++  L  ++ V F  I ++
Sbjct: 73  KIAVEAMDQLLQACHSSPSLPQFSENHLRMVQRLLESNNA-KMEQLATDSFVTFSNIEES 131

Query: 149 DGTYMFNLEGFIPKLCQLAQ-----EVGDDERALLLRSAGLQTLSSMV-KFMGEHSHLSM 202
             +Y    + FI K  Q+         GDD R  L R AGL+ L  +V K + +  H ++
Sbjct: 132 SPSYHRQYDFFIDKFSQMCHANPQAAYGDDFR--LARCAGLRGLRGVVWKSVTDDLHPNI 189

Query: 203 ----DFDKIISAILENYVDLQSKSNLAKVEKLNSQSQNQLVQEFPKEEAHVSSMLNVATG 258
                 DKI+ +IL N   LQ   +  K       S +Q+    PK +       N    
Sbjct: 190 WEQQHMDKIVPSILFN---LQEPDDSGK-----GFSSSQI----PKFD-------NTFAD 230

Query: 259 FEIESKLDTAKNPAYWSKVCLYNIAKLAKEATTVRRVLEPLFHYFDTENHWSSEKGVAYC 318
                ++D    P   S  CL  +   A    ++R V+EP+  + D    W+     ++ 
Sbjct: 231 STQSHRVDDEATPKVLSDRCLRELMGKASFG-SLRAVIEPVLKHMDLHKRWTPPP--SFA 287

Query: 319 VLMYLQFLLAESGNNSHLMLSILVKHLDHKNVAKQPILQIDIINITTQVAQNVKQQASVA 378
           + ++   + +    NS+ ++  L+ HLD    +     +I I  + + +           
Sbjct: 288 IHVFRAIIYSIQSQNSYFVIQELINHLD-SMCSADASTRIGIATVLSSIVSIAGTSIGPL 346

Query: 379 VIGAISDLIKHLR 391
           ++   + L+KHLR
Sbjct: 347 LLSIFNSLLKHLR 359


>Y143_HUMAN (Q14156) Hypothetical protein KIAA0143 (Fragment)
          Length = 885

 Score = 75.9 bits (185), Expect = 5e-13
 Identities = 93/412 (22%), Positives = 170/412 (40%), Gaps = 56/412 (13%)

Query: 15  LCIFCPSLRARSRQPVKRYKKLIAEILPRNKVAELNDRKIGKLCEYASKNPLRIPKITEN 74
           +C  C +LR R       YK+L+  I P +    L    + KL  YA   P ++ +I   
Sbjct: 69  VCCCCSALRPR-------YKRLVDNIFPEDPKDGLVKTDMEKLTFYAVSAPEKLDRIGSY 121

Query: 75  LEQRCYKDLRNESFGSVKVILCIYRKLLSSCREQ-IPLFASSLLGIIRTLLEQTRADEVR 133
           L +R  +D+     G V + +    +LL +C  Q I  F  S L ++  LLE +   +++
Sbjct: 122 LAERLSRDVVRHRSGYVLIAMEALDQLLMACHSQSIKPFVESFLHMVAKLLE-SGEPKLQ 180

Query: 134 ILGCNTLVDFIIFQTD-GTYMFNLEGFIPKLCQLAQEV-GDDERALLLRSAGLQTLSSMV 191
           +LG N+ V F   + D  +Y    + F+ +   +      D E    +R AG++ +  +V
Sbjct: 181 VLGTNSFVKFANIEEDTPSYHRRYDFFVSRFSAMCHSCHSDPEIRTEIRIAGIRGIQGVV 240

Query: 192 -KFMGEHSHLSM----DFDKIISAILENYVDLQSKSNLAKVEKLNSQSQNQLVQEFPKEE 246
            K + +    ++      DKI+ ++L          N+ K+E+++S+             
Sbjct: 241 RKTVNDELRATIWEPQHMDKIVPSLL---------FNMQKIEEVDSRIGPP--------- 282

Query: 247 AHVSSMLNVATGFEIESKLDTAKNPAYWSKVCLYNIAKLAKEATTVRRVLEPLFHYFDTE 306
                           S  D  +NPA  ++ C   +   A     +   + P+F + D  
Sbjct: 283 -------------SSPSATDKEENPAVLAENCFRELLGRATFG-NMNNAVRPVFAHLDHH 328

Query: 307 NHWSSEKGVAYCVLMYLQFLLAESGNNSHLMLSILVKHLDHKNVAKQPILQIDIINITTQ 366
             W   +   +C  + +  + A+    SH ++  ++ HLD +     P ++  II +  +
Sbjct: 329 KLWDPNEFAVHCFKIIMYSIQAQ---YSHHVIQEILGHLDARK-KDAPRVRAGIIQVLLE 384

Query: 367 -VAQNVKQQASVAVIGAISDLIKHLRRCLQNSAEATDI-GNDAHTLNTKLQS 416
            VA   K      V+   + L+KHLR  L    EA D+ G    ++N    S
Sbjct: 385 AVAIAAKGSIGPTVLEVFNTLLKHLR--LSVEFEANDLQGGSVGSVNLNTSS 434


>REST_HUMAN (P30622) Restin (Cytoplasmic linker protein-170 alpha-2)
            (CLIP-170) (Reed-Sternberg intermediate filament
            associated protein)
          Length = 1427

 Score = 34.7 bits (78), Expect = 1.2
 Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 7/93 (7%)

Query: 158  GFIPKLCQLAQEVGDDERALLLRSAGLQTLSSMVKFMGEHSHLSMDFDKIISAILENYVD 217
            G + +L +L ++  D  +A       +Q +  M K   E +  S++  K  +A L+N +D
Sbjct: 1056 GLLQELEELRKQA-DKAKAAQTAEDAMQIMEQMTKEKTE-TLASLEDTKQTNAKLQNELD 1113

Query: 218  LQSKSNLAKVEKLNSQS-----QNQLVQEFPKE 245
               ++NL  VE+LN        +NQ ++EF KE
Sbjct: 1114 TLKENNLKNVEELNKSKELLTVENQKMEEFRKE 1146


>FSHR_RAT (P20395) Follicle stimulating hormone receptor precursor
           (FSH-R) (Follitropin receptor)
          Length = 692

 Score = 32.7 bits (73), Expect = 4.7
 Identities = 20/70 (28%), Positives = 34/70 (48%)

Query: 436 FDLMAVVLENVSSSTIVARTTISAVYQTAKLITSVPNVLYHNKAFPDALFHQLLLAMAHP 495
           ++++ V++  +S   I   TT+  V  T++   +VP  L  N AF D      LL +A  
Sbjct: 361 YNILRVLIWFISILAITGNTTVLVVLTTSQYKLTVPRFLMCNLAFADLCIGIYLLLIASV 420

Query: 496 DRETQIGAHS 505
           D  T+   H+
Sbjct: 421 DIHTKSQYHN 430


>FSHR_MOUSE (P35378) Follicle stimulating hormone receptor precursor
           (FSH-R) (Follitropin receptor)
          Length = 692

 Score = 32.7 bits (73), Expect = 4.7
 Identities = 20/70 (28%), Positives = 34/70 (48%)

Query: 436 FDLMAVVLENVSSSTIVARTTISAVYQTAKLITSVPNVLYHNKAFPDALFHQLLLAMAHP 495
           ++++ V++  +S   I   TT+  V  T++   +VP  L  N AF D      LL +A  
Sbjct: 361 YNILRVLIWFISILAITGNTTVLVVLTTSQYKLTVPRFLMCNLAFADLCIGIYLLLIASV 420

Query: 496 DRETQIGAHS 505
           D  T+   H+
Sbjct: 421 DIHTKSQYHN 430


>YE38_SCHPO (O13892) Hypothetical protein C20G4.08 in chromosome I
          Length = 1076

 Score = 32.3 bits (72), Expect = 6.1
 Identities = 35/148 (23%), Positives = 66/148 (43%), Gaps = 14/148 (9%)

Query: 123 LLEQTRADEVRILGCNTLVDFIIFQTDGTYMFNLEGFIPKLCQLAQEVGDDERALLLRSA 182
           LLE   A+E       ++V   + +  G     LE  + K  Q+A +   +E A  +R+A
Sbjct: 751 LLEYKAANEKHTEAILSVVSSTLTENTGKI---LESVVEKSMQVALK---EEIANSVRNA 804

Query: 183 GLQTLSSMVKFMGE-----HSHLSMDFDKIISAILENYVDLQSKSNLAKVEKLNSQSQNQ 237
               L  +  F+        + +  DFDK  S++ +    +Q   N+A  +K +    N+
Sbjct: 805 LKNNLEKIESFLENSIAELQNSVREDFDKQTSSLAQLRYSIQ---NVAHAQKESEVKYNE 861

Query: 238 LVQEFPKEEAHVSSMLNVATGFEIESKL 265
           L ++    E +V ++L      +IE+K+
Sbjct: 862 LNEQVKTLEGYVETVLEKFNDLKIENKV 889


>PS12_MOUSE (Q80ZC9) Psoriasis susceptibility 1 candidate gene 2
           protein homolog precursor (SPR1 protein)
          Length = 134

 Score = 32.3 bits (72), Expect = 6.1
 Identities = 14/29 (48%), Positives = 16/29 (54%)

Query: 794 PDDAYPSGPPLFMETPRPGSPLAQIEFPD 822
           P D +P  PPLF E P PGS     + PD
Sbjct: 48  PGDPWPGAPPLFDEPPPPGSNRPWRDLPD 76


>IF2P_YEAST (P39730) Eukaryotic translation initiation factor 5B
           (eIF-5B) (Translation initiation factor IF-2)
          Length = 1002

 Score = 32.0 bits (71), Expect = 8.0
 Identities = 16/59 (27%), Positives = 35/59 (59%)

Query: 523 KKISKKVESDGLSIQHESLSGEDPLNGKPVEEKPIHHSLISMILVELLCWWAFSNQLVK 581
           +++ K   + G++++ E  SG+ P+ G+ V+E    +SL+S   ++ L   AF +Q+ +
Sbjct: 928 QEVKKGQTAAGVAVRLEDPSGQQPIWGRHVDENDTLYSLVSRRSIDTLKDKAFRDQVAR 986


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.323    0.137    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 98,331,183
Number of Sequences: 164201
Number of extensions: 3860639
Number of successful extensions: 13629
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 13618
Number of HSP's gapped (non-prelim): 12
length of query: 951
length of database: 59,974,054
effective HSP length: 120
effective length of query: 831
effective length of database: 40,269,934
effective search space: 33464315154
effective search space used: 33464315154
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 71 (32.0 bits)