BLASTP 2.2.2 [Dec-14-2001]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= AC146571.3 + phase: 0 
         (444 letters)

Database: sprot 
           164,201 sequences; 59,974,054 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

RLUD_XANAC (Q8PHN2) Ribosomal large subunit pseudouridine syntha...    59  3e-08
Y209_MYCPN (P75485) Hypothetical pseudouridine synthase MG209 ho...    58  6e-08
RLUD_XYLFT (Q87AR7) Ribosomal large subunit pseudouridine syntha...    56  2e-07
RLUC_BUCBP (Q89AH2) Ribosomal large subunit pseudouridine syntha...    55  4e-07
YG3X_YEAST (P53294) Hypothetical 46.8 kDa protein in CLC1-PDS2 i...    55  5e-07
RLUC_BUCAP (Q8K9J8) Ribosomal large subunit pseudouridine syntha...    54  6e-07
RLUC_BUCAI (P57430) Ribosomal large subunit pseudouridine syntha...    54  6e-07
RLUC_HAEDU (P59835) Ribosomal large subunit pseudouridine syntha...    50  9e-06
RLUC_PASMU (Q9CM51) Ribosomal large subunit pseudouridine syntha...    49  2e-05
RLUD_RALSO (Q8XYX8) Ribosomal large subunit pseudouridine syntha...    49  3e-05
Y042_HAEIN (P43930) Hypothetical pseudouridine synthase HI0042 (...    47  8e-05
RIB2_YEAST (Q12362) DRAP deaminase                                     46  2e-04
YA32_SCHPO (Q09709) Hypothetical protein C18B11.02c in chromosome I    45  3e-04
RLUC_ECOL6 (Q8FIP7) Ribosomal large subunit pseudouridine syntha...    45  3e-04
YLP4_ZYMMO (O66114) Hypothetical pseudouridine synthase in lpd 3...    45  4e-04
Y347_HELPJ (Q9ZMA1) Hypothetical pseudouridine synthase JHP0321 ...    45  5e-04
TRUC_ERWCA (Q47417) tRNA pseudouridine synthase C (EC 4.2.1.70) ...    44  6e-04
Y347_HELPY (O25114) Hypothetical pseudouridine synthase HP0347 (...    44  8e-04
RLUC_VIBPA (Q87N15) Ribosomal large subunit pseudouridine syntha...    44  8e-04
TRUC_PASMU (Q9CNF3) tRNA pseudouridine synthase C (EC 4.2.1.70) ...    43  0.002

>RLUD_XANAC (Q8PHN2) Ribosomal large subunit pseudouridine synthase
           D (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil
           hydrolyase)
          Length = 331

 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 52/186 (27%), Positives = 85/186 (44%), Gaps = 21/186 (11%)

Query: 188 IIAVEESYVVLDKPAGTSVGETTGNIEESCVT---FATRALGLTTPLITTHQIDNCTEGC 244
           ++  +E  +V+DKPAG  V    GN + + V    F   AL         H++D  T G 
Sbjct: 92  VLYEDEQVLVIDKPAGLVVHPGAGNPDRTLVNALLFRDPALASVPRAGVVHRLDKDTSGV 151

Query: 245 VVLARNKEYCSVFHCKIREKKVKKIYLALAASPLPIGIIKHYMRPTNTAPRLISEDCIKG 304
           +V+AR  +  +    ++  ++V + YLA+    L  G   +   P +  PR    D +K 
Sbjct: 152 MVVARTVQAQTALVEQLSAREVHRQYLAVVVGALVSGGTAN--APIDRHPR----DRLK- 204

Query: 305 WHICQLEVMDCRKIPWPAIVVQDEYCGWPSQDYAYECKINLLTGRTHQIRAQFAACKAPI 364
                + V D  +       +++ +        A EC++   TGRTHQIR   A  K+PI
Sbjct: 205 -----MAVRDDGRDAVTHYRLRERF----RAHTALECRLE--TGRTHQIRVHMAHLKSPI 253

Query: 365 IGDTMY 370
           +GD +Y
Sbjct: 254 VGDPLY 259


>Y209_MYCPN (P75485) Hypothetical pseudouridine synthase MG209
           homolog (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil
           hydrolyase) (H10_orf309)
          Length = 309

 Score = 57.8 bits (138), Expect = 6e-08
 Identities = 62/276 (22%), Positives = 108/276 (38%), Gaps = 42/276 (15%)

Query: 106 FALVSPEPPPTATAEQIRIFEQVTEPLVLQKRSSLKGKTIREAQKTFRVTDANQFVEPGT 165
           F++ + +   T  A  + +       L++    S+ GK         ++T     V+P  
Sbjct: 5   FSVTTAQRLDTFLATLLNLSRVKVAKLIVDGLVSVNGK---------KITKNGWLVQPED 55

Query: 166 YLRVHVHPKRFPRC----YEIDWRSRIIAVEESYVVLDKPAGTSVGETTGNIEESCVTFA 221
            + V+   + F +        D+   I+  +E  +V++KP G     T+ N  ES +  A
Sbjct: 56  RVHVNWSEELFEKVPVEVQPYDFPLDILYEDEQIMVVNKPNGLISHPTSFNESESLLGAA 115

Query: 222 TRALGLTTPLITTHQIDNCTEGCVVLARNKEYCSVFHCKIREKKVKKIYLALAASPLPIG 281
                   P+   H++D  T G ++LA+N+        +++++ +K+ YLAL   PL   
Sbjct: 116 LFHCN-HQPVFLVHRLDRDTSGVIMLAKNQSSLLHLQKQLQQRVMKRYYLALVHFPL--- 171

Query: 282 IIKHYMRPTNTAPRLISEDCIKGWHICQLEVMDCRKIPW-------PAIVVQDEYCGWPS 334
                             D + G     LE +   K+ W        A     ++     
Sbjct: 172 ------------------DSLSGTISAPLERVGNNKVMWKVGNSSNKAKNAFTKFTVLNQ 213

Query: 335 QDYAYECKINLLTGRTHQIRAQFAACKAPIIGDTMY 370
            + A   K  LLTGRTHQIR      K P+  D +Y
Sbjct: 214 NEKAALIKCELLTGRTHQIRVHLQFIKHPVYNDPLY 249


>RLUD_XYLFT (Q87AR7) Ribosomal large subunit pseudouridine synthase
           D (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil
           hydrolyase)
          Length = 331

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 50/186 (26%), Positives = 82/186 (43%), Gaps = 21/186 (11%)

Query: 188 IIAVEESYVVLDKPAGTSVGETTGNIEESCVTFATR---ALGLTTPLITTHQIDNCTEGC 244
           I+  +E   V++KPAG  V    GN + + V        AL         H++D  T G 
Sbjct: 92  ILYEDEHVFVINKPAGLVVHPGAGNPDGTLVNALLHRDPALAAVPRAGVVHRLDKDTSGV 151

Query: 245 VVLARNKEYCSVFHCKIREKKVKKIYLALAASPLPIGIIKHYMRPTNTAPRLISEDCIKG 304
           +V+AR  +  +    ++  ++V + YLA+  S L  G   +     +   RL        
Sbjct: 152 MVVARTLQAQTALVEQLSSRQVHRQYLAVVVSALVSGGTVNAAIERHPRDRL-------- 203

Query: 305 WHICQLEVMDCRKIPWPAIVVQDEYCGWPSQDYAYECKINLLTGRTHQIRAQFAACKAPI 364
               ++EV D  K       +++ +        A EC+++  TGRTHQIR   A  + PI
Sbjct: 204 ----RMEVSDTGKEAVTHYRLRERF----RAHTALECRLD--TGRTHQIRVHMAHLRHPI 253

Query: 365 IGDTMY 370
           +GD +Y
Sbjct: 254 VGDRLY 259


>RLUC_BUCBP (Q89AH2) Ribosomal large subunit pseudouridine synthase
           C (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil
           hydrolyase)
          Length = 315

 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 50/188 (26%), Positives = 83/188 (43%), Gaps = 21/188 (11%)

Query: 186 SRIIAVEESY-VVLDKPAGTSVGETTGNIEESCVTFATRALGLTTPLITTHQIDNCTEGC 244
           + +I  E++Y ++L+KP+G SV   +G I    +            L   H++D  T G 
Sbjct: 92  NNMILYEDNYFLILNKPSGMSVHSGSG-INYGMIENLRILRPYNRYLDLVHRLDRDTSGV 150

Query: 245 VVLARNKEYCSVFHCKIREKKVKKIYLALAASPLPIGIIKHYMRPTNTAPRLISEDCIKG 304
           +++A+ +      H ++REKK+KK Y+AL     P  I+K   +P      L+     K 
Sbjct: 151 LIIAKKRSILRNLHEQLREKKIKKKYVALVHGVWP-DILKSISKP------LLKTSSRKN 203

Query: 305 WHICQLEVMDCRKIPWPAIVVQDEYCGWPSQDYAYECKINL--LTGRTHQIRAQFAACKA 362
            +I +++      I    I           + Y     I++  +TGRTHQIR        
Sbjct: 204 KNIVKIDPKGKESITHFNI----------KKKYTKNTLISITPITGRTHQIRVHLLHLNY 253

Query: 363 PIIGDTMY 370
           PI+ D  Y
Sbjct: 254 PIVLDAKY 261


>YG3X_YEAST (P53294) Hypothetical 46.8 kDa protein in CLC1-PDS2
           intergenic region
          Length = 404

 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 50/191 (26%), Positives = 87/191 (45%), Gaps = 15/191 (7%)

Query: 188 IIAVEESYVVLDKPAGTSVGETTGNIEESCVTFATRALGLTTPLITTHQIDNCTEGCVVL 247
           I+  +ES +V+DKP+G  V   TG   ++ +T   +  G+    +  +++D  T G ++L
Sbjct: 121 IVFEDESILVIDKPSGIPV-HPTGQFYQNTITELLKLHGVDA--LPCYRLDKITSGLLIL 177

Query: 248 ARNKEYCSVFHCKIREKKVKKIYLALAASPLPIG-IIKHYMRPTNTAPRLISEDCIKGWH 306
           A+N +        IR + + KIYLA      P   +I        T     S+  ++   
Sbjct: 178 AKNSQSAGEIQKSIRSRDMIKIYLARVKGRFPHSELILDNENAAETTFEDTSKVTVEMTP 237

Query: 307 ICQLEVMDCRKIPWPAIVVQDEYCG-WPSQDYAY------ECKINLLTGRTHQIRAQFAA 359
           I  ++    R+ P      +D     +P + +++       CK   +TGRTHQIR   A 
Sbjct: 238 IYSIDPK--RQFPVGLSTSKDAITKFYPIRYFSHADETVVACK--PITGRTHQIRIHLAR 293

Query: 360 CKAPIIGDTMY 370
              PI+ D++Y
Sbjct: 294 LGHPIVNDSVY 304


>RLUC_BUCAP (Q8K9J8) Ribosomal large subunit pseudouridine synthase
           C (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil
           hydrolyase)
          Length = 314

 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 55/193 (28%), Positives = 87/193 (44%), Gaps = 37/193 (19%)

Query: 189 IAVEESYV-VLDKPAGTSVGETTGNIEESCVTFATRALGLTTPLITTHQIDNCTEGCVVL 247
           I  E++Y+ +++KP+G +V   +G I    + +  +   L   L   H+ID  T G ++L
Sbjct: 94  ILYEDNYLLIINKPSGIAVHGGSG-INLGVIEYFRKIRPLEKFLELVHRIDRDTSGVLML 152

Query: 248 ARNKEYCSVFHCKIREKKVKKIYLALAASPLPIGIIKHYMRPTNTAPRLISEDCIKGWHI 307
           A+ +      H +IREKKV+K Y+AL     P+ +            R +SE  +K  H+
Sbjct: 153 AKKRRSLLSLHKQIREKKVQKKYIALVHGLWPLSL------------RKVSEPLLK-THL 199

Query: 308 CQLEVMDCRKIPWPAIVVQDEYCGWPSQDYAYECKINLL----------TGRTHQIRAQF 357
                    K     I++  E  G P++ Y ++ K   L          TGRTHQIR   
Sbjct: 200 ---------KNKQRKILINKE--GKPAETY-FKIKKQYLFTTLVSITPKTGRTHQIRVHT 247

Query: 358 AACKAPIIGDTMY 370
                PI+ D  Y
Sbjct: 248 LHAGHPILFDKRY 260


>RLUC_BUCAI (P57430) Ribosomal large subunit pseudouridine synthase
           C (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil
           hydrolyase)
          Length = 314

 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 55/205 (26%), Positives = 90/205 (43%), Gaps = 36/205 (17%)

Query: 176 FPRCYEIDWRSRIIAVEESYVVLDKPAGTSVGETTGNIEESCVTFATRALGLTTPLITTH 235
           FP  +  +  +RI+  +   ++++KP+G +V   +G +    + +  +   L   L   H
Sbjct: 82  FPLNHSTNLLNRILYEDSHLLIINKPSGIAVHGGSG-LNFGVIEYFRKLRPLNKFLELVH 140

Query: 236 QIDNCTEGCVVLARNKEYCSVFHCKIREKKVKKIYLALAASPLPIGIIKHYMRPTNTAPR 295
           +ID  T G ++LA+ +      H ++REKK+KK Y+AL     P  I K           
Sbjct: 141 RIDRDTSGVLILAKKRTSLVSLHEQLREKKIKKEYIALVHGLWPDHIKK----------- 189

Query: 296 LISEDCIKGWHICQLEVMDCRKIPWPAIVVQDEYCGWPSQDYAYECK----------INL 345
            ISE  +K      ++  + +K      +V  +  G PS+ Y ++ K          I  
Sbjct: 190 -ISEPLLK------IQFKNKQK------MVLIDKKGKPSETY-FQIKKKFSSSTLLSIIP 235

Query: 346 LTGRTHQIRAQFAACKAPIIGDTMY 370
            TGRTHQIR        PI  D  Y
Sbjct: 236 KTGRTHQIRVHALHAGHPIFFDKRY 260


>RLUC_HAEDU (P59835) Ribosomal large subunit pseudouridine synthase
           C (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil
           hydrolyase)
          Length = 320

 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 61/205 (29%), Positives = 91/205 (43%), Gaps = 31/205 (15%)

Query: 188 IIAVEESYVVLDKPAGTSV----GETTGNIEESCVTFATRALGLTTPLIT-THQIDNCTE 242
           I+  ++  +VL+KP+G  V    G + G IE      A RAL      +   H+ID  T 
Sbjct: 98  ILYEDDVMLVLNKPSGIGVHGGSGLSFGVIE------ALRALRPQARFLELVHRIDRDTS 151

Query: 243 GCVVLARNKEYCSVFHCKIREKKVKKIYLALAAS--PLPIGIIKHYMRPTNTAPRLISED 300
           G +++A+ +      H ++REK V+K YLAL        I +IK        AP L+  +
Sbjct: 152 GILLVAKKRSALRALHEQLREKVVQKDYLALVRGQWQAHINVIK--------AP-LLKNE 202

Query: 301 CIKGWHICQLEVMDCRKIPWPAIVVQDEYCGWPSQDYAYECKINLLTGRTHQIRAQFAAC 360
              G  I  ++V +  K       +++ Y        A   K + +TGRTHQIR      
Sbjct: 203 LQSGERI--VKVSEQGKPSETRFSIEERY------PNATLIKASPITGRTHQIRVHTQYA 254

Query: 361 KAPIIGDTMYMPAAI-AEMINPGLN 384
             PI  D  Y   A  A++   GLN
Sbjct: 255 GHPIACDDRYGDQAFDAKLKQAGLN 279


>RLUC_PASMU (Q9CM51) Ribosomal large subunit pseudouridine synthase
           C (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil
           hydrolyase)
          Length = 326

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 52/187 (27%), Positives = 85/187 (44%), Gaps = 22/187 (11%)

Query: 187 RIIAVEESYVVLDKPAGTSVGETTG---NIEESCVTFATRALGLTTPLITTHQIDNCTEG 243
           +I+  +E  +VL+KP+G +V   +G    + E+  T    A  L       H++D  T G
Sbjct: 100 QILFEDECLLVLNKPSGIAVHGGSGLSFGVIEALRTLRPDARFLEL----VHRLDRDTSG 155

Query: 244 CVVLARNKEYCSVFHCKIREKKVKKIYLALAASPLPIGIIKHYMRPTNTAPRLISEDCIK 303
            +++A+ +      H ++REK V+K YLAL       G  + + +    AP L+  +   
Sbjct: 156 ILLVAKKRSALRSLHEQLREKTVQKDYLALVR-----GQWQSHCKVVK-AP-LLKNELSS 208

Query: 304 GWHICQLEVMDCRKIPWPAIVVQDEYCGWPSQDYAYECKINLLTGRTHQIRAQFAACKAP 363
           G  I  + V +  K       +++ Y      +YA   K + +TGRTHQIR        P
Sbjct: 209 GERI--VRVSEQGKPSETRFSIEERY------EYATLVKASPVTGRTHQIRVHTQYAGHP 260

Query: 364 IIGDTMY 370
           I  D  Y
Sbjct: 261 IALDDKY 267


>RLUD_RALSO (Q8XYX8) Ribosomal large subunit pseudouridine synthase
           D (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil
           hydrolyase)
          Length = 358

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 50/193 (25%), Positives = 86/193 (43%), Gaps = 29/193 (15%)

Query: 188 IIAVEESYVVLDKPAGTSV----GETTGNIEESCVTFATRALGLTTPLITTHQIDNCTEG 243
           ++  +++ +V++KPAG  V    G  +G +    +    +A GL    I  H++D  T G
Sbjct: 118 VVYEDDTLLVINKPAGLVVHPAAGNWSGTVLNGLLHRYPQAAGLPRAGIV-HRLDKETSG 176

Query: 244 CVVLARNKEYCSVFHCKIREKKVKKIYLALAASPLP-IGIIKHYM-RPTNTAPRLISEDC 301
            +V+AR     +    +++ + VK+ YLAL     P  G I   + R      R+   + 
Sbjct: 177 LMVVARTLPAQTDLVRQLQARTVKRTYLALVWGETPEAGTIDAPIGRDPRDRTRMAIIET 236

Query: 302 IKG----WHICQLEVMDCRKIPWPAIVVQDEYCGWPSQDYAYECKINLLTGRTHQIRAQF 357
             G     H   L+V+D  +                +Q    +C++   TGRTHQIR  F
Sbjct: 237 ASGKPARTHFKTLDVVDLGR----------------AQVSLVQCQLE--TGRTHQIRVHF 278

Query: 358 AACKAPIIGDTMY 370
            +   P++GD +Y
Sbjct: 279 ESEGHPLLGDPVY 291


>Y042_HAEIN (P43930) Hypothetical pseudouridine synthase HI0042 (EC
           4.2.1.70) (Pseudouridylate synthase) (Uracil hydrolyase)
          Length = 224

 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 52/199 (26%), Positives = 82/199 (41%), Gaps = 53/199 (26%)

Query: 188 IIAVEESYVVLDKPAGTSVGETTGNIEESCVTFATRALGLTTPLI-TTHQIDNCTEGCVV 246
           ++     +++++K  G SV +     EE  +T    A  L  P +   H++D  T G ++
Sbjct: 5   VVYQHSDFIIINKSEGISVHKDQ---EEQGLTELV-AKQLNVPKVWLVHRLDKVTSGLLI 60

Query: 247 LARNKEYCSVFHCKIREKKVKKIYLALAASPLPIGIIKHYMRPTNTAPR----LISEDCI 302
           LA N E  + F     E K+ K YLAL+                N  P+    LI  D  
Sbjct: 61  LALNAESAAEFSRLFSEHKIHKTYLALS----------------NQKPKKKQGLIIGDMK 104

Query: 303 KG----WHICQLEVMDCRKIPWPAIVVQDEYCGWPSQDYAYECKINLL-------TGRTH 351
           K     W +CQ +         PAI          ++  +  C+ NL        TG+TH
Sbjct: 105 KAREGAWKLCQTKDN-------PAI----------TRFESVSCEPNLRLFILKPQTGKTH 147

Query: 352 QIRAQFAACKAPIIGDTMY 370
           Q+R    +  +PI+GD +Y
Sbjct: 148 QLRVAMKSLGSPILGDGLY 166


>RIB2_YEAST (Q12362) DRAP deaminase
          Length = 591

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 64/261 (24%), Positives = 105/261 (39%), Gaps = 27/261 (10%)

Query: 136 KRSSLKGKTIREAQKTFRVTDAN--QFVEPGTYLRVHVHPKRFPRCYE-IDWRSRIIAVE 192
           +  S   KTI E +       AN    +  G  +   VH    P   + ID    I+  +
Sbjct: 112 REPSYYSKTIAEGKVYLNDEPANLDTIIRDGDLITHKVHRHEPPVTSKPID----IVFED 167

Query: 193 ESYVVLDKPAGTSVGETTGNIEESCVT-FATRALGLTTPLITTHQIDNCTEGCVVLARNK 251
           E  +V+DKP+   V   TG    + +T    R LG +      +++D  T G + LA+  
Sbjct: 168 EDILVIDKPSSIPV-HPTGRYRFNTITKMLERQLGYSVH--PCNRLDKPTSGLMFLAKTP 224

Query: 252 EYCSVFHCKIREKKVKKIYLALAASPLPIGIIKHYMRPTNTAPRLISEDCIKGWHICQLE 311
                   +++ ++V K Y+A      PIGI++      +  P++          +C++ 
Sbjct: 225 LGADRMGDQMKAREVTKEYVARVKGEFPIGIVEVDKPVRSVNPKVALNA------VCEMS 278

Query: 312 VMDCRKIPWPAIVVQDEYCGWPSQDYAYECKINLLTGRTHQIRAQFAACKAPIIGDTMYM 371
             + +      +  +  Y G   Q    +CK   LTGRTHQIR        PI  D +Y 
Sbjct: 279 DENAKHAK--TVFQRVSYDG---QTSIVKCKP--LTGRTHQIRVHLQYLGFPIANDPIY- 330

Query: 372 PAAIAEMINPGLNPFGKYNKD 392
             +  ++  P L   G  N D
Sbjct: 331 --SNPDIWGPDLGRGGLQNYD 349


>YA32_SCHPO (Q09709) Hypothetical protein C18B11.02c in chromosome I
          Length = 394

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 56/243 (23%), Positives = 90/243 (36%), Gaps = 34/243 (13%)

Query: 136 KRSSLKGKTIREAQKTF--RVTDANQFVEPGTYLRVHVHPKRFPRCYEIDWRSRIIAVEE 193
           + S    K IR  Q     ++ + +  +E G  +  H H    P     D    I+  +E
Sbjct: 56  RESGYYEKAIRNGQVKVNNQIGNVDTLIENGYIVSHHAHRHEPPVS---DQPVGIVHEDE 112

Query: 194 SYVVLDKPAGTSVGETTGNIEESCVTFATRALGLTTPLITTHQIDNCTEGCVVLARNKEY 253
           SYVV+DKPAG  V   TG    + V          + L   +++D  T G +  +++ + 
Sbjct: 113 SYVVIDKPAGVPV-HPTGRYNHNTVLHILMKENKCSLLYPCNRLDRLTSGLMFFSKSPKA 171

Query: 254 CSVFHCKIREKKVKKIYLALAASPLPIGIIKHYMRPTNTAPRLISEDCIKGWHICQLEVM 313
                  +  K +KK Y+A                      R+I E    G  IC   ++
Sbjct: 172 AEEMRVHMISKSLKKEYVA----------------------RVIGEFPNSGEVICDAPLL 209

Query: 314 D-CRKIPWPAIVVQDEYCGWPSQDYAYECKINL-----LTGRTHQIRAQFAACKAPIIGD 367
                +    I    +      +  A++   +L     LTGRTHQ+R        PI  D
Sbjct: 210 TVAPTLGLNRIHPDGKEASTVFKRIAFDGHTSLVLCKPLTGRTHQLRVHLQYLGYPIAND 269

Query: 368 TMY 370
            +Y
Sbjct: 270 PIY 272


>RLUC_ECOL6 (Q8FIP7) Ribosomal large subunit pseudouridine synthase
           C (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil
           hydrolyase)
          Length = 319

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 55/200 (27%), Positives = 89/200 (44%), Gaps = 27/200 (13%)

Query: 177 PRCYEIDWRSRIIAVEESYV-VLDKPAGTSV----GETTGNIEESCVTFATRALGLTTPL 231
           P   ++   + +I  E+ ++ VL+KP+GT+V    G + G IE        RAL      
Sbjct: 83  PHLQKVAALADVILYEDDHILVLNKPSGTAVHGGSGLSFGVIE------GLRALRPEARF 136

Query: 232 IT-THQIDNCTEGCVVLARNKEYCSVFHCKIREKKVKKIYLALAASPLPIGIIKHYMRPT 290
           +   H++D  T G +++A+ +      H ++REK ++K YLAL       G  + Y++  
Sbjct: 137 LELVHRLDRDTSGVLLVAKKRSALRSLHEQLREKGMQKDYLALVR-----GQWQSYVKSV 191

Query: 291 NTAPRLISEDCIKGWHICQLEVMDCRKIPWPAIVVQDEYCGWPSQDYAYECKINLLTGRT 350
             AP L+      G  I  + V    K       V++ Y       +A   + + +TGRT
Sbjct: 192 Q-AP-LLKNILQSGERI--VRVSQEGKPSETRFKVEERYA------FATLVRCSPVTGRT 241

Query: 351 HQIRAQFAACKAPIIGDTMY 370
           HQIR        PI  D  Y
Sbjct: 242 HQIRVHTQYAGHPIAFDDRY 261


>YLP4_ZYMMO (O66114) Hypothetical pseudouridine synthase in lpd
           3'region (EC 4.2.1.70) (Pseudouridylate synthase)
           (Uracil hydrolyase) (ORF4)
          Length = 219

 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 48/188 (25%), Positives = 74/188 (38%), Gaps = 22/188 (11%)

Query: 187 RIIAVEESYVVLDKPAG---TSVGETTGNIEESCVTFATRALGLTTPLITTHQIDNCTEG 243
           R++ ++   +++DKPAG   TSV + + ++E      A+   G        H++D  T G
Sbjct: 7   RVLFIDAEAMIIDKPAGLPVTSVRDGSLSLENY---LASLCFGFKRWPSIVHRLDRDTSG 63

Query: 244 CVVLARNKEYCSVFHCKIREKKVKKIYLALAASPLPIGIIKHYMRPTNTAPRLISEDCIK 303
           C++LARN +          + +VKK Y A+         +      T   P L       
Sbjct: 64  CLLLARNPKMHRRLSEAFSQGQVKKCYWAILEG------VPEKNEGTIDLPLLKISSPKS 117

Query: 304 GWHICQLEVMDCRKIPWPAIVVQDEYCGWPSQDYAYECKINLLTGRTHQIRAQFA-ACKA 362
           GW I   +        W  +       G     +  E      TGRTHQ+R   A     
Sbjct: 118 GWRIVADDKGKRAVTHWEILAKNK---GRSLVAFRPE------TGRTHQLRVHAATGLGL 168

Query: 363 PIIGDTMY 370
           PI+GD  Y
Sbjct: 169 PIVGDPFY 176


>Y347_HELPJ (Q9ZMA1) Hypothetical pseudouridine synthase JHP0321 (EC
           4.2.1.70) (Pseudouridylate synthase) (Uracil hydrolyase)
          Length = 293

 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 50/186 (26%), Positives = 77/186 (40%), Gaps = 14/186 (7%)

Query: 185 RSRIIAVEESYVVLDKPAGTSVGETTGNIEESCVTFATRALGLTTPLITTHQIDNCTEGC 244
           + +++   + + V DKPA            ES +       G        H++D  T G 
Sbjct: 68  QEKLVFEAKDFGVFDKPAQIYTHPKGYFYHESLLDCIQSHFGKNAH--PAHRLDYETSGL 125

Query: 245 VVLARNKEYCSVFHCKIREKKVKKIYLALAASPLPIGIIKHYMRPTNTAPRLISEDCIKG 304
           V+  +  +          +KKVKK YLALA   +   II +  +P  T P+ I +D    
Sbjct: 126 VLAGKTLQSTKDLKALFMQKKVKKTYLALAHGLVDKSIIIN--KPILT-PQNIQKDLRIR 182

Query: 305 WHICQLEVMDCRKIPWPAIVVQDEYCGWPSQDYAYECKINLLTGRTHQIRAQFAACKAPI 364
             I  L          P+I + +     P  D +   KI  LTGRTHQIR   ++    I
Sbjct: 183 SQISPLGK--------PSITLVEPLSYNPFLDISL-LKITPLTGRTHQIRLHLSSVDHRI 233

Query: 365 IGDTMY 370
           +G+ +Y
Sbjct: 234 VGEGLY 239


>TRUC_ERWCA (Q47417) tRNA pseudouridine synthase C (EC 4.2.1.70)
           (Pseudouridylate synthase) (Uracil hydrolyase)
          Length = 376

 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 45/192 (23%), Positives = 82/192 (42%), Gaps = 23/192 (11%)

Query: 188 IIAVEESYVVLDKPAGTSVGETTGNIEESCVTFATRALGLTTPLITTHQIDNCTEGCVVL 247
           II  +E  V ++KP+G  V  +  + +E  V   T    +   + T H++D  T G ++L
Sbjct: 118 IIYQDEHLVAVNKPSGWLVHRSWLDRKEKVVVMQTVRDQIGQHVYTVHRLDRPTSGVLLL 177

Query: 248 ARNKEYCSVFHCKIREKKVKKIYLALAASPLPIGIIKHYMRPTNTAPRLISEDCIKGWHI 307
           A + E       +    +++K Y A         +++ Y+         ++E+  K    
Sbjct: 178 ALSSEVARALSQQFESHQMQKTYHA---------VVRGYVLDDGVIDYALTEELDK---- 224

Query: 308 CQLEVMDCRKIPWPAI-----VVQDE----YCGWPSQDYAYECKINLLTGRTHQIRAQFA 358
              +  +  K P PA+     + Q E       +P+  Y+   ++   TGR HQ+R   +
Sbjct: 225 IADKFTNPDKAPQPAVTHYRSLAQAEMPVAIGRYPTARYSL-MELKPQTGRKHQLRRHMS 283

Query: 359 ACKAPIIGDTMY 370
               PIIGDT +
Sbjct: 284 HIHHPIIGDTAH 295


>Y347_HELPY (O25114) Hypothetical pseudouridine synthase HP0347 (EC
           4.2.1.70) (Pseudouridylate synthase) (Uracil hydrolyase)
          Length = 298

 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 40/136 (29%), Positives = 64/136 (46%), Gaps = 12/136 (8%)

Query: 235 HQIDNCTEGCVVLARNKEYCSVFHCKIREKKVKKIYLALAASPLPIGIIKHYMRPTNTAP 294
           H++D  T G V+  +  +          +KKVKK YLALA      G+++  M+     P
Sbjct: 116 HRLDYETSGLVLAGKTLQSVKDLKALFMQKKVKKTYLALAH-----GLVEKSMKIDK--P 168

Query: 295 RLISEDCIKGWHICQLEVMDCRKIPWPAIVVQDEYCGWPSQDYAYECKINLLTGRTHQIR 354
            L  ++  K  HI + ++    K    +I + +     P  D +   KI  LTGRTHQIR
Sbjct: 169 ILTPQNIQKDLHI-RSKISPLGK---QSITLVEPLSYNPFLDISL-LKITPLTGRTHQIR 223

Query: 355 AQFAACKAPIIGDTMY 370
              ++    I+G+ +Y
Sbjct: 224 LHLSSVDHRIVGEGLY 239


>RLUC_VIBPA (Q87N15) Ribosomal large subunit pseudouridine synthase
           C (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil
           hydrolyase)
          Length = 315

 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 48/188 (25%), Positives = 79/188 (41%), Gaps = 29/188 (15%)

Query: 188 IIAVEESYVVLDKPAGTSV----GETTGNIEESCVTFATRALGLTTPLIT-THQIDNCTE 242
           II  ++  ++L+KP+GT+V    G   G IE      A RAL      +   H+ID  T 
Sbjct: 96  IIYEDDHMLILNKPSGTAVHGGSGLKFGAIE------ALRALRPQARFLELVHRIDRDTS 149

Query: 243 GCVVLARNKEYCSVFHCKIREKKVKKIYLALAASPLPIGIIKHYMRPTNTAPRLISEDCI 302
           G +++A+ +        + REK VKK Y AL             M    ++ ++++   +
Sbjct: 150 GILLVAKKRSALRHLQAQFREKTVKKFYFALV------------MGQWKSSCKVVNAPLL 197

Query: 303 KGWHICQLEVMDCRKIPWPAIVVQDEYCGWPSQDYAYECKINLLTGRTHQIRAQFAACKA 362
           K      + V    K       + +++      + A   + + +TGRTHQIR        
Sbjct: 198 KNEVNSIVRVNPNGKPSETRFKILEKF------EQATLIQASPITGRTHQIRVHTQYTGH 251

Query: 363 PIIGDTMY 370
           PI  D  Y
Sbjct: 252 PIAWDDRY 259


>TRUC_PASMU (Q9CNF3) tRNA pseudouridine synthase C (EC 4.2.1.70)
           (Pseudouridylate synthase) (Uracil hydrolyase)
          Length = 243

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 44/186 (23%), Positives = 82/186 (43%), Gaps = 12/186 (6%)

Query: 189 IAVEESYVV-LDKPAGTSVGETTGNIEESCVTFATRALGLTTPLITTHQIDNCTEGCVVL 247
           I  ++ Y++ ++KPAG  V  +  +  E+     T    +   +   H++D  T G ++ 
Sbjct: 5   ILYQDPYLIAVNKPAGMLVHRSWLDRHETQFVMQTLRDQIGQHVYPIHRLDRPTSGVLLF 64

Query: 248 ARNKEYCSVFHCKIREKKVKKIYLALAASPL-PIGIIKHYMRP--TNTAPRLISEDCIKG 304
           A + E  ++   +   K+V+K YLA+    L   G I + ++      A +   +D  K 
Sbjct: 65  ALSSEVANLLCLQFENKQVQKSYLAIVRGYLVGEGRIDYPLKVQLDKIADKFAQDD--KA 122

Query: 305 WHICQLEVMDCRKIPWPAIVVQDEYCGWPSQDYAYECKINLLTGRTHQIRAQFAACKAPI 364
                 + +   K+  P  V +     +P+  Y+   ++   TGR HQ+R        PI
Sbjct: 123 PQEAVTDYLGLAKVEMPYCVKK-----YPTTRYSL-VRLIPHTGRKHQLRRHMKHLFHPI 176

Query: 365 IGDTMY 370
           +GDT Y
Sbjct: 177 LGDTQY 182


  Database: sprot
    Posted date:  Nov 25, 2004 10:54 AM
  Number of letters in database: 59,974,054
  Number of sequences in database:  164,201
  
Lambda     K      H
   0.321    0.137    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,959,767
Number of Sequences: 164201
Number of extensions: 2377204
Number of successful extensions: 4712
Number of sequences better than 10.0: 99
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 4538
Number of HSP's gapped (non-prelim): 160
length of query: 444
length of database: 59,974,054
effective HSP length: 113
effective length of query: 331
effective length of database: 41,419,341
effective search space: 13709801871
effective search space used: 13709801871
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)